N-[4-[2-amino-5-(1-cyclohexylpyrazol-4-yl)-3-pyridinyl]-3-fluorophenyl]-6-cyano-1-cyclopropyl-5-(4-fluorophenyl)-4-oxopyridine-3-carboxamide;N-[4-[2-amino-5-(1-cyclohexylpyrazol-4-yl)-3-pyridinyl]-3-fluorophenyl]-6-cyano-5-cyclopropyl-1-(4-fluorophenyl)-2-oxopyridine-3-carboxamide;N-[4-[2-amino-5-(1-ethylpyrazol-4-yl)-3-pyridinyl]-3-fluorophenyl]-6-cyano-1-cyclopropyl-5-(4-fluorophenyl)-4-oxopyridine-3-carboxamide;N-[4-[2-amino-5-(1-ethylpyrazol-4-yl)-3-pyridinyl]-3-fluorophenyl]-6-cyano-5-cyclopropyl-1-(4-fluorophenyl)-2-oxopyridine-3-carboxamide;N-[4-[2-amino-5-[1-(1-methylpiperidin-4-yl)pyrazol-4-yl]-3-pyridinyl]-3-fluorophenyl]-6-cyano-5-cyclopropyl-1-(4-fluorophenyl)-2-oxopyridine-3-carboxamide

C172H144F10N36O10 — CID 163770927

IUPACN-[4-[2-amino-5-(1-cyclohexylpyrazol-4-yl)-3-pyridinyl]-3-fluorophenyl]-6-cyano-1-cyclopropyl-5-(4-fluorophenyl)-4-oxopyridine-3-carboxamide;N-[4-[2-amino-5-(1-cyclohexylpyrazol-4-yl)-3-pyridinyl]-3-fluorophenyl]-6-cyano-5-cyclopropyl-1-(4-fluorophenyl)-2-oxopyridine-3-carboxamide;N-[4-[2-amino-5-(1-ethylpyrazol-4-yl)-3-pyridinyl]-3-fluorophenyl]-6-cyano-1-cyclopropyl-5-(4-fluorophenyl)-4-oxopyridine-3-carboxamide;N-[4-[2-amino-5-(1-ethylpyrazol-4-yl)-3-pyridinyl]-3-fluorophenyl]-6-cyano-5-cyclopropyl-1-(4-fluorophenyl)-2-oxopyridine-3-carboxamide;N-[4-[2-amino-5-[1-(1-methylpiperidin-4-yl)pyrazol-4-yl]-3-pyridinyl]-3-fluorophenyl]-6-cyano-5-cyclopropyl-1-(4-fluorophenyl)-2-oxopyridine-3-carboxamide
SMILESCCn1cc(-c2cnc(N)c(-c3ccc(NC(=O)c4cc(C5CC5)c(C#N)n(-c5ccc(F)cc5)c4=O)cc3F)c2)cn1.CCn1cc(-c2cnc(N)c(-c3ccc(NC(=O)c4cn(C5CC5)c(C#N)c(-c5ccc(F)cc5)c4=O)cc3F)c2)cn1.CN1CCC(n2cc(-c3cnc(N)c(-c4ccc(NC(=O)c5cc(C6CC6)c(C#N)n(-c6ccc(F)cc6)c5=O)cc4F)c3)cn2)CC1.N#Cc1c(-c2ccc(F)cc2)c(=O)c(C(=O)Nc2ccc(-c3cc(-c4cnn(C5CCCCC5)c4)cnc3N)c(F)c2)cn1C1CC1.N#Cc1c(C2CC2)cc(C(=O)Nc2ccc(-c3cc(-c4cnn(C5CCCCC5)c4)cnc3N)c(F)c2)c(=O)n1-c1ccc(F)cc1
InChIInChI=1S/C36H32F2N8O2.2C36H31F2N7O2.2C32H25F2N7O2/c1-44-12-10-26(11-13-44)45-20-23(19-42-45)22-14-30(34(40)41-18-22)28-9-6-25(15-32(28)38)43-35(47)31-16-29(21-2-3-21)33(17-39)46(36(31)48)27-7-4-24(37)5-8-27;37-24-8-6-21(7-9-24)33-32(16-39)44(26-11-12-26)20-30(34(33)46)36(47)43-25-10-13-28(31(38)15-25)29-14-22(17-41-35(29)40)23-18-42-45(19-23)27-4-2-1-3-5-27;37-24-8-11-27(12-9-24)45-33(17-39)29(21-6-7-21)16-31(36(45)47)35(46)43-25-10-13-28(32(38)15-25)30-14-22(18-41-34(30)40)23-19-42-44(20-23)26-4-2-1-3-5-26;1-2-40-16-20(15-38-40)19-11-25(31(36)37-14-19)24-10-7-22(12-27(24)34)39-32(43)26-17-41(23-8-9-23)28(13-35)29(30(26)42)18-3-5-21(33)6-4-18;1-2-40-17-20(16-38-40)19-11-26(30(36)37-15-19)24-10-7-22(12-28(24)34)39-31(42)27-13-25(18-3-4-18)29(14-35)41(32(27)43)23-8-5-21(33)6-9-23/h4-9,14-16,18-21,26H,2-3,10-13H2,1H3,(H2,40,41)(H,43,47);6-10,13-15,17-20,26-27H,1-5,11-12H2,(H2,40,41)(H,43,47);8-16,18-21,26H,1-7H2,(H2,40,41)(H,43,46);3-7,10-12,14-17,23H,2,8-9H2,1H3,(H2,36,37)(H,39,43);5-13,15-18H,2-4H2,1H3,(H2,36,37)(H,39,42)
InChIKeyMGJHJSKJONUBNP-UHFFFAOYSA-N
MW3065.27 g/mol
LogP31.71
Rot. Bonds35

About N-[4-[2-amino-5-(1-cyclohexylpyrazol-4-yl)-3-pyridinyl]-3-fluorophenyl]-6-cyano-1-cyclopropyl-5-(4-fluorophenyl)-4-oxopyridine-3-carboxamide;N-[4-[2-amino-5-(1-cyclohexylpyrazol-4-yl)-3-pyridinyl]-3-fluorophenyl]-6-cyano-5-cyclopropyl-1-(4-fluorophenyl)-2-oxopyridine-3-carboxamide;N-[4-[2-amino-5-(1-ethylpyrazol-4-yl)-3-pyridinyl]-3-fluorophenyl]-6-cyano-1-cyclopropyl-5-(4-fluorophenyl)-4-oxopyridine-3-carboxamide;N-[4-[2-amino-5-(1-ethylpyrazol-4-yl)-3-pyridinyl]-3-fluorophenyl]-6-cyano-5-cyclopropyl-1-(4-fluorophenyl)-2-oxopyridine-3-carboxamide;N-[4-[2-amino-5-[1-(1-methylpiperidin-4-yl)pyrazol-4-yl]-3-pyridinyl]-3-fluorophenyl]-6-cyano-5-cyclopropyl-1-(4-fluorophenyl)-2-oxopyridine-3-carboxamide

N-[4-[2-amino-5-(1-cyclohexylpyrazol-4-yl)-3-pyridinyl]-3-fluorophenyl]-6-cyano-1-cyclopropyl-5-(4-fluorophenyl)-4-oxopyridine-3-carboxamide;N-[4-[2-amino-5-(1-cyclohexylpyrazol-4-yl)-3-pyridinyl]-3-fluorophenyl]-6-cyano-5-cyclopropyl-1-(4-fluorophenyl)-2-oxopyridine-3-carboxamide;N-[4-[2-amino-5-(1-ethylpyrazol-4-yl)-3-pyridinyl]-3-fluorophenyl]-6-cyano-1-cyclopropyl-5-(4-fluorophenyl)-4-oxopyridine-3-carboxamide;N-[4-[2-amino-5-(1-ethylpyrazol-4-yl)-3-pyridinyl]-3-fluorophenyl]-6-cyano-5-cyclopropyl-1-(4-fluorophenyl)-2-oxopyridine-3-carboxamide;N-[4-[2-amino-5-[1-(1-methylpiperidin-4-yl)pyrazol-4-yl]-3-pyridinyl]-3-fluorophenyl]-6-cyano-5-cyclopropyl-1-(4-fluorophenyl)-2-oxopyridine-3-carboxamide (PubChem CID 163770927) has the molecular formula C172H144F10N36O10 and a molecular weight of 3065.27 g/mol. Its IUPAC name is N-[4-[2-amino-5-(1-cyclohexylpyrazol-4-yl)-3-pyridinyl]-3-fluorophenyl]-6-cyano-1-cyclopropyl-5-(4-fluorophenyl)-4-oxopyridine-3-carboxamide;N-[4-[2-amino-5-(1-cyclohexylpyrazol-4-yl)-3-pyridinyl]-3-fluorophenyl]-6-cyano-5-cyclopropyl-1-(4-fluorophenyl)-2-oxopyridine-3-carboxamide;N-[4-[2-amino-5-(1-ethylpyrazol-4-yl)-3-pyridinyl]-3-fluorophenyl]-6-cyano-1-cyclopropyl-5-(4-fluorophenyl)-4-oxopyridine-3-carboxamide;N-[4-[2-amino-5-(1-ethylpyrazol-4-yl)-3-pyridinyl]-3-fluorophenyl]-6-cyano-5-cyclopropyl-1-(4-fluorophenyl)-2-oxopyridine-3-carboxamide;N-[4-[2-amino-5-[1-(1-methylpiperidin-4-yl)pyrazol-4-yl]-3-pyridinyl]-3-fluorophenyl]-6-cyano-5-cyclopropyl-1-(4-fluorophenyl)-2-oxopyridine-3-carboxamide.

Molecular Properties

Compound NameN-[4-[2-amino-5-(1-cyclohexylpyrazol-4-yl)-3-pyridinyl]-3-fluorophenyl]-6-cyano-1-cyclopropyl-5-(4-fluorophenyl)-4-oxopyridine-3-carboxamide;N-[4-[2-amino-5-(1-cyclohexylpyrazol-4-yl)-3-pyridinyl]-3-fluorophenyl]-6-cyano-5-cyclopropyl-1-(4-fluorophenyl)-2-oxopyridine-3-carboxamide;N-[4-[2-amino-5-(1-ethylpyrazol-4-yl)-3-pyridinyl]-3-fluorophenyl]-6-cyano-1-cyclopropyl-5-(4-fluorophenyl)-4-oxopyridine-3-carboxamide;N-[4-[2-amino-5-(1-ethylpyrazol-4-yl)-3-pyridinyl]-3-fluorophenyl]-6-cyano-5-cyclopropyl-1-(4-fluorophenyl)-2-oxopyridine-3-carboxamide;N-[4-[2-amino-5-[1-(1-methylpiperidin-4-yl)pyrazol-4-yl]-3-pyridinyl]-3-fluorophenyl]-6-cyano-5-cyclopropyl-1-(4-fluorophenyl)-2-oxopyridine-3-carboxamide
PubChem CID163770927
Molecular FormulaC172H144F10N36O10
Molecular Weight3065.27 g/mol
Exact Mass3063.17
IUPAC NameN-[4-[2-amino-5-(1-cyclohexylpyrazol-4-yl)-3-pyridinyl]-3-fluorophenyl]-6-cyano-1-cyclopropyl-5-(4-fluorophenyl)-4-oxopyridine-3-carboxamide;N-[4-[2-amino-5-(1-cyclohexylpyrazol-4-yl)-3-pyridinyl]-3-fluorophenyl]-6-cyano-5-cyclopropyl-1-(4-fluorophenyl)-2-oxopyridine-3-carboxamide;N-[4-[2-amino-5-(1-ethylpyrazol-4-yl)-3-pyridinyl]-3-fluorophenyl]-6-cyano-1-cyclopropyl-5-(4-fluorophenyl)-4-oxopyridine-3-carboxamide;N-[4-[2-amino-5-(1-ethylpyrazol-4-yl)-3-pyridinyl]-3-fluorophenyl]-6-cyano-5-cyclopropyl-1-(4-fluorophenyl)-2-oxopyridine-3-carboxamide;N-[4-[2-amino-5-[1-(1-methylpiperidin-4-yl)pyrazol-4-yl]-3-pyridinyl]-3-fluorophenyl]-6-cyano-5-cyclopropyl-1-(4-fluorophenyl)-2-oxopyridine-3-carboxamide
SMILESCCn1cc(-c2cnc(N)c(-c3ccc(NC(=O)c4cc(C5CC5)c(C#N)n(-c5ccc(F)cc5)c4=O)cc3F)c2)cn1.CCn1cc(-c2cnc(N)c(-c3ccc(NC(=O)c4cn(C5CC5)c(C#N)c(-c5ccc(F)cc5)c4=O)cc3F)c2)cn1.CN1CCC(n2cc(-c3cnc(N)c(-c4ccc(NC(=O)c5cc(C6CC6)c(C#N)n(-c6ccc(F)cc6)c5=O)cc4F)c3)cn2)CC1.N#Cc1c(-c2ccc(F)cc2)c(=O)c(C(=O)Nc2ccc(-c3cc(-c4cnn(C5CCCCC5)c4)cnc3N)c(F)c2)cn1C1CC1.N#Cc1c(C2CC2)cc(C(=O)Nc2ccc(-c3cc(-c4cnn(C5CCCCC5)c4)cnc3N)c(F)c2)c(=O)n1-c1ccc(F)cc1
InChIInChI=1S/C36H32F2N8O2.2C36H31F2N7O2.2C32H25F2N7O2/c1-44-12-10-26(11-13-44)45-20-23(19-42-45)22-14-30(34(40)41-18-22)28-9-6-25(15-32(28)38)43-35(47)31-16-29(21-2-3-21)33(17-39)46(36(31)48)27-7-4-24(37)5-8-27;37-24-8-6-21(7-9-24)33-32(16-39)44(26-11-12-26)20-30(34(33)46)36(47)43-25-10-13-28(31(38)15-25)29-14-22(17-41-35(29)40)23-18-42-45(19-23)27-4-2-1-3-5-27;37-24-8-11-27(12-9-24)45-33(17-39)29(21-6-7-21)16-31(36(45)47)35(46)43-25-10-13-28(32(38)15-25)30-14-22(18-41-34(30)40)23-19-42-44(20-23)26-4-2-1-3-5-26;1-2-40-16-20(15-38-40)19-11-25(31(36)37-14-19)24-10-7-22(12-27(24)34)39-32(43)26-17-41(23-8-9-23)28(13-35)29(30(26)42)18-3-5-21(33)6-4-18;1-2-40-17-20(16-38-40)19-11-26(30(36)37-15-19)24-10-7-22(12-28(24)34)39-31(42)27-13-25(18-3-4-18)29(14-35)41(32(27)43)23-8-5-21(33)6-9-23/h4-9,14-16,18-21,26H,2-3,10-13H2,1H3,(H2,40,41)(H,43,47);6-10,13-15,17-20,26-27H,1-5,11-12H2,(H2,40,41)(H,43,47);8-16,18-21,26H,1-7H2,(H2,40,41)(H,43,46);3-7,10-12,14-17,23H,2,8-9H2,1H3,(H2,36,37)(H,39,43);5-13,15-18H,2-4H2,1H3,(H2,36,37)(H,39,42)
InChIKeyMGJHJSKJONUBNP-UHFFFAOYSA-N
XLogP31.71
TPSA661.34 Ų
H-Bond Donors10
H-Bond Acceptors41
Rotatable Bonds35
Heavy Atoms228
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5003065.27
LogP ≤ 531.71
H-Bond Donors ≤ 510
H-Bond Acceptors ≤ 1041

Analyze N-[4-[2-amino-5-(1-cyclohexylpyrazol-4-yl)-3-pyridinyl]-3-fluorophenyl]-6-cyano-1-cyclopropyl-5-(4-fluorophenyl)-4-oxopyridine-3-carboxamide;N-[4-[2-amino-5-(1-cyclohexylpyrazol-4-yl)-3-pyridinyl]-3-fluorophenyl]-6-cyano-5-cyclopropyl-1-(4-fluorophenyl)-2-oxopyridine-3-carboxamide;N-[4-[2-amino-5-(1-ethylpyrazol-4-yl)-3-pyridinyl]-3-fluorophenyl]-6-cyano-1-cyclopropyl-5-(4-fluorophenyl)-4-oxopyridine-3-carboxamide;N-[4-[2-amino-5-(1-ethylpyrazol-4-yl)-3-pyridinyl]-3-fluorophenyl]-6-cyano-5-cyclopropyl-1-(4-fluorophenyl)-2-oxopyridine-3-carboxamide;N-[4-[2-amino-5-[1-(1-methylpiperidin-4-yl)pyrazol-4-yl]-3-pyridinyl]-3-fluorophenyl]-6-cyano-5-cyclopropyl-1-(4-fluorophenyl)-2-oxopyridine-3-carboxamide with MolForge

Explore ADMET properties, 3D molecular structure, drug-likeness score, and discover similar compounds using our AI-powered platform.

Launch Full Analysis

Related Compounds

N-[4-[2-amino-5-[1-(1-methylpiperidin-4-yl)pyrazol-4-yl]-3-pyridinyl]-3-fluorophenyl]-6-cyano-5-(4-fluorophenyl)-4-oxo-1-propan-2-ylpyridine-3-carboxamide
CID 146424744
N-[4-[2-amino-5-(1-piperidin-4-ylpyrazol-4-yl)-3-pyridinyl]-3-fluorophenyl]-6-cyano-1-cyclopropyl-5-(4-fluorophenyl)-4-oxopyridine-3-carboxamide
CID 146432426
N-[4-[2-amino-5-(1-piperidin-4-ylpyrazol-4-yl)-3-pyridinyl]-3-fluorophenyl]-6-cyano-5-(4-fluorophenyl)-4-oxo-1-propan-2-ylpyridine-3-carboxamide
CID 151992044
N-benzyl-6-[3-pyridin-3-yl-5-(trifluoromethyl)pyrazol-1-yl]pyridine-3-carboxamide;N-cyclohexyl-6-[3-pyridin-3-yl-5-(trifluoromethyl)pyrazol-1-yl]pyridine-3-carboxamide;N-(3,3-diphenylpropyl)-6-[3-pyridin-3-yl-5-(trifluoromethyl)pyrazol-1-yl]pyridine-3-carboxamide;N-hexyl-6-[3-pyridin-3-yl-5-(trifluoromethyl)pyrazol-1-yl]pyridine-3-carboxamide;N-(2-phenylethyl)-4-[5-pyridin-3-yl-3-(trifluoromethyl)pyrazol-1-yl]benzamide;N-(3-phenylpropyl)-4-[5-pyridin-3-yl-3-(trifluoromethyl)pyrazol-1-yl]benzamide
CID 157141744
(2S)-N-[5-(3,3-difluoropyrrolidin-1-yl)-2-pyridinyl]-2-[2-(4-methylphenyl)ethylamino]-2-phenylacetamide;(2R)-N-[5-(3,3-difluoropyrrolidin-1-yl)-2-pyridinyl]-2-[2-(4-methylphenyl)ethylamino]-2-phenylacetamide;(2R)-N-[5-(3-ethyl-2-oxoimidazolidin-1-yl)-2-pyridinyl]-2-[2-(4-methylphenyl)ethylamino]-2-phenylacetamide;(2S)-N-[5-(3-ethyl-2-oxoimidazolidin-1-yl)-2-pyridinyl]-2-[2-(4-methylphenyl)ethylamino]-2-phenylacetamide;(2R)-N-[3-fluoro-5-(1-methylpyrazol-4-yl)-2-pyridinyl]-2-[2-(4-methylphenyl)ethylamino]-2-phenylacetamide;(2S)-N-[3-fluoro-5-(1-methylpyrazol-4-yl)-2-pyridinyl]-2-[2-(4-methylphenyl)ethylamino]-2-phenylacetamide
CID 157287413
N-[5-[1-amino-1-(3-cyanophenyl)-3-cyclopropylpropyl]-2-fluorophenyl]-2-(1-aminoisoquinolin-7-yl)-5-methylpyrazole-3-carboxamide;2-[5-(1-amino-3-cyclopropyl-1-phenylpropyl)-2-fluorophenyl]-1-[2-(1-aminoisoquinolin-7-yl)-5-methylpyrazol-3-yl]ethanone;N-[5-(1-amino-3-cyclopropyl-1-pyridin-4-ylpropyl)-2-fluorophenyl]-1-(1-methylisoquinolin-7-yl)-5-(trifluoromethyl)pyrazole-3-carboxamide;1-[2-(1-aminoisoquinolin-7-yl)-5-methylpyrazol-3-yl]-2-[5-[(cyclopropylmethylamino)-phenylmethyl]-2-fluorophenyl]ethanone
CID 157407134
2,6-difluoro-N-[5-[1-methyl-3-(2-methylphenyl)pyrazol-5-yl]-2-pyridinyl]benzamide;2,6-difluoro-N-[5-[1-methyl-4-(trifluoromethyl)pyrrol-2-yl]-2-pyridinyl]benzamide;N-[5-[3-(2,6-difluorophenyl)-1-methylpyrazol-5-yl]-2-pyridinyl]-2,6-difluorobenzamide;N-[5-[3-(2,6-difluorophenyl)-1-methylpyrazol-5-yl]-2-pyridinyl]-2-fluorobenzamide;N-[5-[3-(2,6-difluorophenyl)-1-methylpyrazol-5-yl]-2-pyridinyl]-2-methylbenzamide;2-fluoro-N-[5-[1-methyl-3-(2-methylphenyl)pyrazol-5-yl]-2-pyridinyl]benzamide;2-methyl-N-[5-[1-methyl-3-(2-methylphenyl)pyrazol-5-yl]-2-pyridinyl]benzamide
CID 157943421
N-cyclopropyl-4-[3-[difluoro-(4-fluoro-2-methylindazol-5-yl)methyl]-[1,2,4]triazolo[4,3-b]pyridazin-6-yl]-2-fluorobenzamide;1-cyclopropyl-2-[4-[3-[difluoro-(4-fluoro-2-methylindazol-5-yl)methyl]-[1,2,4]triazolo[4,3-b]pyridazin-6-yl]-2-fluorophenyl]ethanone;4-[3-[difluoro-(4-fluoro-2-methylindazol-5-yl)methyl]-[1,2,4]triazolo[4,3-b]pyridazin-6-yl]-2,6-difluoro-N-methylbenzamide;4-[3-[difluoro-(4-fluoro-2-methylindazol-5-yl)methyl]-[1,2,4]triazolo[4,3-b]pyridazin-6-yl]-N-ethyl-2-fluorobenzamide;4-[3-[difluoro-(4-fluoro-2-methylindazol-5-yl)methyl]-[1,2,4]triazolo[4,3-b]pyridazin-6-yl]-2-fluoro-N,N-dimethylbenzamide;bis(4-[3-[difluoro-(4-fluoro-2-methylindazol-5-yl)methyl]-[1,2,4]triazolo[4,3-b]pyridazin-6-yl]-2-fluoro-N-methylbenzamide);4-[3-[difluoro-(4-fluoro-2-methylindazol-5-yl)methyl]-[1,2,4]triazolo[4,3-b]pyridazin-6-yl]-2-fluoro-N-propan-2-ylbenzamide
CID 159081768
2,6-difluoro-N-[5-[1-methyl-4-(trifluoromethyl)pyrrol-2-yl]pyrazin-2-yl]benzamide;2,6-difluoro-N-[5-[1-methyl-4-(trifluoromethyl)pyrrol-2-yl]-2-pyridinyl]benzamide;N-[5-[3-(2,6-difluorophenyl)-1-methylpyrazol-5-yl]-2-pyridinyl]-2,6-difluorobenzamide;N-[5-[3-(2,6-difluorophenyl)-1-methylpyrazol-5-yl]-2-pyridinyl]-2-fluorobenzamide;N-[5-[3-(2,6-difluorophenyl)-1-methylpyrazol-5-yl]-2-pyridinyl]-2-methylbenzamide
CID 159408728
N-[5-[1-amino-3-cyclopropyl-1-(3-methylphenyl)propyl]-2-fluorophenyl]-2-(1-aminoisoquinolin-7-yl)-5-methylpyrazole-3-carboxamide;N-[5-(1-amino-3-cyclopropyl-1-pyridin-4-ylpropyl)-2-fluorophenyl]-1-(1-methylisoquinolin-7-yl)-5-(trifluoromethyl)pyrazole-3-carboxamide;1-[2-(1-aminoisoquinolin-7-yl)-5-methylpyrazol-3-yl]-2-[5-[(cyclopropylmethylamino)-phenylmethyl]-2-fluorophenyl]ethanone;1-[1-[3-[2-[2-(1-aminoisoquinolin-7-yl)-5-methylpyrazol-3-yl]-2-oxoethyl]-4-fluorophenyl]-3-cyclopropylpropyl]pyridin-2-one
CID 160712043
N-[5-(1-amino-3-cyclopropyl-1-pyridin-4-ylpropyl)-2-fluorophenyl]-1-(1-methylisoquinolin-7-yl)-5-(trifluoromethyl)pyrazole-3-carboxamide;2-(1-aminoisoquinolin-7-yl)-N-[5-[3-cyclopropyl-1-(2-oxo-1-pyridinyl)propyl]-2-fluorophenyl]-5-methylpyrazole-3-carboxamide;1-[1-[3-[2-[2-(1-aminoisoquinolin-7-yl)-5-methylpyrazol-3-yl]-2-oxoethyl]-4-fluorophenyl]-3-cyclopropylpropyl]pyridin-2-one;1-[1-[3-[2-[2-(1-aminoisoquinolin-7-yl)-5-methylpyrazol-3-yl]-2-oxoethyl]-4-fluorophenyl]-3-cyclopropylpropyl]pyrimidine-2,4-dione
CID 161513998
N-[5-[3-(2,6-difluorocyclohexa-1,3-dien-1-yl)-1-methylpyrazol-5-yl]-2-pyridinyl]-2-methylbenzamide;2,6-difluoro-N-[5-[1-methyl-4-(trifluoromethyl)pyrrol-2-yl]pyrazin-2-yl]benzamide;2,6-difluoro-N-[5-[1-methyl-4-(trifluoromethyl)pyrrol-2-yl]-2-pyridinyl]benzamide;N-[5-[3-(2,6-difluorophenyl)-1-methylpyrazol-5-yl]-2-pyridinyl]-2,6-difluorobenzamide;N-[5-[3-(2,6-difluorophenyl)-1-methylpyrazol-5-yl]-2-pyridinyl]-2-fluorobenzamide;2-fluoro-N-[5-[1-methyl-3-(2-methylphenyl)pyrazol-5-yl]-2-pyridinyl]benzamide;2-methyl-N-[5-[1-methyl-3-(2-methylphenyl)pyrazol-5-yl]-2-pyridinyl]benzamide
CID 161645545

Frequently Asked Questions

What is the IUPAC name of N-[4-[2-amino-5-(1-cyclohexylpyrazol-4-yl)-3-pyridinyl]-3-fluorophenyl]-6-cyano-1-cyclopropyl-5-(4-fluorophenyl)-4-oxopyridine-3-carboxamide;N-[4-[2-amino-5-(1-cyclohexylpyrazol-4-yl)-3-pyridinyl]-3-fluorophenyl]-6-cyano-5-cyclopropyl-1-(4-fluorophenyl)-2-oxopyridine-3-carboxamide;N-[4-[2-amino-5-(1-ethylpyrazol-4-yl)-3-pyridinyl]-3-fluorophenyl]-6-cyano-1-cyclopropyl-5-(4-fluorophenyl)-4-oxopyridine-3-carboxamide;N-[4-[2-amino-5-(1-ethylpyrazol-4-yl)-3-pyridinyl]-3-fluorophenyl]-6-cyano-5-cyclopropyl-1-(4-fluorophenyl)-2-oxopyridine-3-carboxamide;N-[4-[2-amino-5-[1-(1-methylpiperidin-4-yl)pyrazol-4-yl]-3-pyridinyl]-3-fluorophenyl]-6-cyano-5-cyclopropyl-1-(4-fluorophenyl)-2-oxopyridine-3-carboxamide?
The IUPAC name of N-[4-[2-amino-5-(1-cyclohexylpyrazol-4-yl)-3-pyridinyl]-3-fluorophenyl]-6-cyano-1-cyclopropyl-5-(4-fluorophenyl)-4-oxopyridine-3-carboxamide;N-[4-[2-amino-5-(1-cyclohexylpyrazol-4-yl)-3-pyridinyl]-3-fluorophenyl]-6-cyano-5-cyclopropyl-1-(4-fluorophenyl)-2-oxopyridine-3-carboxamide;N-[4-[2-amino-5-(1-ethylpyrazol-4-yl)-3-pyridinyl]-3-fluorophenyl]-6-cyano-1-cyclopropyl-5-(4-fluorophenyl)-4-oxopyridine-3-carboxamide;N-[4-[2-amino-5-(1-ethylpyrazol-4-yl)-3-pyridinyl]-3-fluorophenyl]-6-cyano-5-cyclopropyl-1-(4-fluorophenyl)-2-oxopyridine-3-carboxamide;N-[4-[2-amino-5-[1-(1-methylpiperidin-4-yl)pyrazol-4-yl]-3-pyridinyl]-3-fluorophenyl]-6-cyano-5-cyclopropyl-1-(4-fluorophenyl)-2-oxopyridine-3-carboxamide (CID 163770927) is N-[4-[2-amino-5-(1-cyclohexylpyrazol-4-yl)-3-pyridinyl]-3-fluorophenyl]-6-cyano-1-cyclopropyl-5-(4-fluorophenyl)-4-oxopyridine-3-carboxamide;N-[4-[2-amino-5-(1-cyclohexylpyrazol-4-yl)-3-pyridinyl]-3-fluorophenyl]-6-cyano-5-cyclopropyl-1-(4-fluorophenyl)-2-oxopyridine-3-carboxamide;N-[4-[2-amino-5-(1-ethylpyrazol-4-yl)-3-pyridinyl]-3-fluorophenyl]-6-cyano-1-cyclopropyl-5-(4-fluorophenyl)-4-oxopyridine-3-carboxamide;N-[4-[2-amino-5-(1-ethylpyrazol-4-yl)-3-pyridinyl]-3-fluorophenyl]-6-cyano-5-cyclopropyl-1-(4-fluorophenyl)-2-oxopyridine-3-carboxamide;N-[4-[2-amino-5-[1-(1-methylpiperidin-4-yl)pyrazol-4-yl]-3-pyridinyl]-3-fluorophenyl]-6-cyano-5-cyclopropyl-1-(4-fluorophenyl)-2-oxopyridine-3-carboxamide.
What is the SMILES notation for N-[4-[2-amino-5-(1-cyclohexylpyrazol-4-yl)-3-pyridinyl]-3-fluorophenyl]-6-cyano-1-cyclopropyl-5-(4-fluorophenyl)-4-oxopyridine-3-carboxamide;N-[4-[2-amino-5-(1-cyclohexylpyrazol-4-yl)-3-pyridinyl]-3-fluorophenyl]-6-cyano-5-cyclopropyl-1-(4-fluorophenyl)-2-oxopyridine-3-carboxamide;N-[4-[2-amino-5-(1-ethylpyrazol-4-yl)-3-pyridinyl]-3-fluorophenyl]-6-cyano-1-cyclopropyl-5-(4-fluorophenyl)-4-oxopyridine-3-carboxamide;N-[4-[2-amino-5-(1-ethylpyrazol-4-yl)-3-pyridinyl]-3-fluorophenyl]-6-cyano-5-cyclopropyl-1-(4-fluorophenyl)-2-oxopyridine-3-carboxamide;N-[4-[2-amino-5-[1-(1-methylpiperidin-4-yl)pyrazol-4-yl]-3-pyridinyl]-3-fluorophenyl]-6-cyano-5-cyclopropyl-1-(4-fluorophenyl)-2-oxopyridine-3-carboxamide?
The canonical SMILES for N-[4-[2-amino-5-(1-cyclohexylpyrazol-4-yl)-3-pyridinyl]-3-fluorophenyl]-6-cyano-1-cyclopropyl-5-(4-fluorophenyl)-4-oxopyridine-3-carboxamide;N-[4-[2-amino-5-(1-cyclohexylpyrazol-4-yl)-3-pyridinyl]-3-fluorophenyl]-6-cyano-5-cyclopropyl-1-(4-fluorophenyl)-2-oxopyridine-3-carboxamide;N-[4-[2-amino-5-(1-ethylpyrazol-4-yl)-3-pyridinyl]-3-fluorophenyl]-6-cyano-1-cyclopropyl-5-(4-fluorophenyl)-4-oxopyridine-3-carboxamide;N-[4-[2-amino-5-(1-ethylpyrazol-4-yl)-3-pyridinyl]-3-fluorophenyl]-6-cyano-5-cyclopropyl-1-(4-fluorophenyl)-2-oxopyridine-3-carboxamide;N-[4-[2-amino-5-[1-(1-methylpiperidin-4-yl)pyrazol-4-yl]-3-pyridinyl]-3-fluorophenyl]-6-cyano-5-cyclopropyl-1-(4-fluorophenyl)-2-oxopyridine-3-carboxamide is CCn1cc(-c2cnc(N)c(-c3ccc(NC(=O)c4cc(C5CC5)c(C#N)n(-c5ccc(F)cc5)c4=O)cc3F)c2)cn1.CCn1cc(-c2cnc(N)c(-c3ccc(NC(=O)c4cn(C5CC5)c(C#N)c(-c5ccc(F)cc5)c4=O)cc3F)c2)cn1.CN1CCC(n2cc(-c3cnc(N)c(-c4ccc(NC(=O)c5cc(C6CC6)c(C#N)n(-c6ccc(F)cc6)c5=O)cc4F)c3)cn2)CC1.N#Cc1c(-c2ccc(F)cc2)c(=O)c(C(=O)Nc2ccc(-c3cc(-c4cnn(C5CCCCC5)c4)cnc3N)c(F)c2)cn1C1CC1.N#Cc1c(C2CC2)cc(C(=O)Nc2ccc(-c3cc(-c4cnn(C5CCCCC5)c4)cnc3N)c(F)c2)c(=O)n1-c1ccc(F)cc1.
What is the InChIKey of N-[4-[2-amino-5-(1-cyclohexylpyrazol-4-yl)-3-pyridinyl]-3-fluorophenyl]-6-cyano-1-cyclopropyl-5-(4-fluorophenyl)-4-oxopyridine-3-carboxamide;N-[4-[2-amino-5-(1-cyclohexylpyrazol-4-yl)-3-pyridinyl]-3-fluorophenyl]-6-cyano-5-cyclopropyl-1-(4-fluorophenyl)-2-oxopyridine-3-carboxamide;N-[4-[2-amino-5-(1-ethylpyrazol-4-yl)-3-pyridinyl]-3-fluorophenyl]-6-cyano-1-cyclopropyl-5-(4-fluorophenyl)-4-oxopyridine-3-carboxamide;N-[4-[2-amino-5-(1-ethylpyrazol-4-yl)-3-pyridinyl]-3-fluorophenyl]-6-cyano-5-cyclopropyl-1-(4-fluorophenyl)-2-oxopyridine-3-carboxamide;N-[4-[2-amino-5-[1-(1-methylpiperidin-4-yl)pyrazol-4-yl]-3-pyridinyl]-3-fluorophenyl]-6-cyano-5-cyclopropyl-1-(4-fluorophenyl)-2-oxopyridine-3-carboxamide?
The InChIKey is MGJHJSKJONUBNP-UHFFFAOYSA-N. The full InChI is InChI=1S/C36H32F2N8O2.2C36H31F2N7O2.2C32H25F2N7O2/c1-44-12-10-26(11-13-44)45-20-23(19-42-45)22-14-30(34(40)41-18-22)28-9-6-25(15-32(28)38)43-35(47)31-16-29(21-2-3-21)33(17-39)46(36(31)48)27-7-4-24(37)5-8-27;37-24-8-6-21(7-9-24)33-32(16-39)44(26-11-12-26)20-30(34(33)46)36(47)43-25-10-13-28(31(38)15-25)29-14-22(17-41-35(29)40)23-18-42-45(19-23)27-4-2-1-3-5-27;37-24-8-11-27(12-9-24)45-33(17-39)29(21-6-7-21)16-31(36(45)47)35(46)43-25-10-13-28(32(38)15-25)30-14-22(18-41-34(30)40)23-19-42-44(20-23)26-4-2-1-3-5-26;1-2-40-16-20(15-38-40)19-11-25(31(36)37-14-19)24-10-7-22(12-27(24)34)39-32(43)26-17-41(23-8-9-23)28(13-35)29(30(26)42)18-3-5-21(33)6-4-18;1-2-40-17-20(16-38-40)19-11-26(30(36)37-15-19)24-10-7-22(12-28(24)34)39-31(42)27-13-25(18-3-4-18)29(14-35)41(32(27)43)23-8-5-21(33)6-9-23/h4-9,14-16,18-21,26H,2-3,10-13H2,1H3,(H2,40,41)(H,43,47);6-10,13-15,17-20,26-27H,1-5,11-12H2,(H2,40,41)(H,43,47);8-16,18-21,26H,1-7H2,(H2,40,41)(H,43,46);3-7,10-12,14-17,23H,2,8-9H2,1H3,(H2,36,37)(H,39,43);5-13,15-18H,2-4H2,1H3,(H2,36,37)(H,39,42).
What are the key properties of N-[4-[2-amino-5-(1-cyclohexylpyrazol-4-yl)-3-pyridinyl]-3-fluorophenyl]-6-cyano-1-cyclopropyl-5-(4-fluorophenyl)-4-oxopyridine-3-carboxamide;N-[4-[2-amino-5-(1-cyclohexylpyrazol-4-yl)-3-pyridinyl]-3-fluorophenyl]-6-cyano-5-cyclopropyl-1-(4-fluorophenyl)-2-oxopyridine-3-carboxamide;N-[4-[2-amino-5-(1-ethylpyrazol-4-yl)-3-pyridinyl]-3-fluorophenyl]-6-cyano-1-cyclopropyl-5-(4-fluorophenyl)-4-oxopyridine-3-carboxamide;N-[4-[2-amino-5-(1-ethylpyrazol-4-yl)-3-pyridinyl]-3-fluorophenyl]-6-cyano-5-cyclopropyl-1-(4-fluorophenyl)-2-oxopyridine-3-carboxamide;N-[4-[2-amino-5-[1-(1-methylpiperidin-4-yl)pyrazol-4-yl]-3-pyridinyl]-3-fluorophenyl]-6-cyano-5-cyclopropyl-1-(4-fluorophenyl)-2-oxopyridine-3-carboxamide?
N-[4-[2-amino-5-(1-cyclohexylpyrazol-4-yl)-3-pyridinyl]-3-fluorophenyl]-6-cyano-1-cyclopropyl-5-(4-fluorophenyl)-4-oxopyridine-3-carboxamide;N-[4-[2-amino-5-(1-cyclohexylpyrazol-4-yl)-3-pyridinyl]-3-fluorophenyl]-6-cyano-5-cyclopropyl-1-(4-fluorophenyl)-2-oxopyridine-3-carboxamide;N-[4-[2-amino-5-(1-ethylpyrazol-4-yl)-3-pyridinyl]-3-fluorophenyl]-6-cyano-1-cyclopropyl-5-(4-fluorophenyl)-4-oxopyridine-3-carboxamide;N-[4-[2-amino-5-(1-ethylpyrazol-4-yl)-3-pyridinyl]-3-fluorophenyl]-6-cyano-5-cyclopropyl-1-(4-fluorophenyl)-2-oxopyridine-3-carboxamide;N-[4-[2-amino-5-[1-(1-methylpiperidin-4-yl)pyrazol-4-yl]-3-pyridinyl]-3-fluorophenyl]-6-cyano-5-cyclopropyl-1-(4-fluorophenyl)-2-oxopyridine-3-carboxamide has a molecular weight of 3065.27 g/mol, XLogP of 31.71, 35 rotatable bonds, 10 hydrogen bond donors, and 41 hydrogen bond acceptors.
Where does this data come from?
All data for N-[4-[2-amino-5-(1-cyclohexylpyrazol-4-yl)-3-pyridinyl]-3-fluorophenyl]-6-cyano-1-cyclopropyl-5-(4-fluorophenyl)-4-oxopyridine-3-carboxamide;N-[4-[2-amino-5-(1-cyclohexylpyrazol-4-yl)-3-pyridinyl]-3-fluorophenyl]-6-cyano-5-cyclopropyl-1-(4-fluorophenyl)-2-oxopyridine-3-carboxamide;N-[4-[2-amino-5-(1-ethylpyrazol-4-yl)-3-pyridinyl]-3-fluorophenyl]-6-cyano-1-cyclopropyl-5-(4-fluorophenyl)-4-oxopyridine-3-carboxamide;N-[4-[2-amino-5-(1-ethylpyrazol-4-yl)-3-pyridinyl]-3-fluorophenyl]-6-cyano-5-cyclopropyl-1-(4-fluorophenyl)-2-oxopyridine-3-carboxamide;N-[4-[2-amino-5-[1-(1-methylpiperidin-4-yl)pyrazol-4-yl]-3-pyridinyl]-3-fluorophenyl]-6-cyano-5-cyclopropyl-1-(4-fluorophenyl)-2-oxopyridine-3-carboxamide is sourced from PubChem (CID 163770927), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).