N-[(1S,2S)-2-(azetidin-1-yl)cyclopentyl]-4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-5-(trifluoromethyl)pyrimidin-2-amine;N-[(1S,2R)-2-(3,3-difluoropropyl)cyclopentyl]-4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-5-(trifluoromethyl)pyrimidin-2-amine;4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-N-[(1S,2S)-2-(3-fluoroazetidin-1-yl)cyclopentyl]-5-(trifluoromethyl)pyrimidin-2-amine;4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-N-[(1S,2R)-2-(3-fluoroazetidin-1-yl)cyclopentyl]-5-(trifluoromethyl)pyrimidin-2-amine;4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-N-[(1S,2R)-2-(3-fluoropropyl)cyclopentyl]-5-(trifluoromethyl)pyrimidin-2-amine;4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-N-[(1S,2S)-2-[(3S)-3-fluoropyrrolidin-1-yl]cyclopentyl]-5-(trifluoromethyl)pyrimidin-2-amine;4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-N-[(1S,2S)-2-[(3R)-3-fluoropyrrolidin-1-yl]cyclopentyl]-5-(trifluoromethyl)pyrimidin-2-amine;4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-N-[(1S,2S)-2-(3-methoxypyrrolidin-1-yl)cyclopentyl]-5-(trifluoromethyl)pyrimidin-2-amine;4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-N-[(1S,2S)-2-pyrrolidin-1-ylcyclobutyl]-5-(trifluoromethyl)pyrimidin-2-amine;2-[[(1S,2S)-2-[[4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-5-(trifluoromethyl)pyrimidin-2-yl]amino]cyclopentyl]amino]ethanol;trans-(1S,2S)-1-N-[4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-5-(trifluoromethyl)pyrimidin-2-yl]-2-N-ethylcyclopentane-1,2-diamine;trans-(1S,2S)-1-N-[4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-5-(trifluoromethyl)pyrimidin-2-yl]-2-N-(2-methoxyethyl)cyclopentane-1,2-diamine

C314H329F43N70O15 — CID 163779613

IUPACN-[(1S,2S)-2-(azetidin-1-yl)cyclopentyl]-4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-5-(trifluoromethyl)pyrimidin-2-amine;N-[(1S,2R)-2-(3,3-difluoropropyl)cyclopentyl]-4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-5-(trifluoromethyl)pyrimidin-2-amine;4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-N-[(1S,2S)-2-(3-fluoroazetidin-1-yl)cyclopentyl]-5-(trifluoromethyl)pyrimidin-2-amine;4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-N-[(1S,2R)-2-(3-fluoroazetidin-1-yl)cyclopentyl]-5-(trifluoromethyl)pyrimidin-2-amine;4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-N-[(1S,2R)-2-(3-fluoropropyl)cyclopentyl]-5-(trifluoromethyl)pyrimidin-2-amine;4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-N-[(1S,2S)-2-[(3S)-3-fluoropyrrolidin-1-yl]cyclopentyl]-5-(trifluoromethyl)pyrimidin-2-amine;4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-N-[(1S,2S)-2-[(3R)-3-fluoropyrrolidin-1-yl]cyclopentyl]-5-(trifluoromethyl)pyrimidin-2-amine;4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-N-[(1S,2S)-2-(3-methoxypyrrolidin-1-yl)cyclopentyl]-5-(trifluoromethyl)pyrimidin-2-amine;4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-N-[(1S,2S)-2-pyrrolidin-1-ylcyclobutyl]-5-(trifluoromethyl)pyrimidin-2-amine;2-[[(1S,2S)-2-[[4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-5-(trifluoromethyl)pyrimidin-2-yl]amino]cyclopentyl]amino]ethanol;trans-(1S,2S)-1-N-[4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-5-(trifluoromethyl)pyrimidin-2-yl]-2-N-ethylcyclopentane-1,2-diamine;trans-(1S,2S)-1-N-[4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-5-(trifluoromethyl)pyrimidin-2-yl]-2-N-(2-methoxyethyl)cyclopentane-1,2-diamine
SMILESCCN[C@H]1CCC[C@@H]1Nc1ncc(C(F)(F)F)c(C2=CCc3nc(-c4c(C)noc4C)ccc32)n1.COC1CCN([C@H]2CCC[C@@H]2Nc2ncc(C(F)(F)F)c(C3=CCc4nc(-c5c(C)noc5C)ccc43)n2)C1.COCCN[C@H]1CCC[C@@H]1Nc1ncc(C(F)(F)F)c(C2=CCc3nc(-c4c(C)noc4C)ccc32)n1.Cc1noc(C)c1-c1ccc2c(n1)CC=C2c1nc(N[C@H]2CCC[C@@H]2CCC(F)F)ncc1C(F)(F)F.Cc1noc(C)c1-c1ccc2c(n1)CC=C2c1nc(N[C@H]2CCC[C@@H]2CCCF)ncc1C(F)(F)F.Cc1noc(C)c1-c1ccc2c(n1)CC=C2c1nc(N[C@H]2CCC[C@@H]2N2CC(F)C2)ncc1C(F)(F)F.Cc1noc(C)c1-c1ccc2c(n1)CC=C2c1nc(N[C@H]2CCC[C@@H]2N2CCC2)ncc1C(F)(F)F.Cc1noc(C)c1-c1ccc2c(n1)CC=C2c1nc(N[C@H]2CCC[C@@H]2N2CC[C@@H](F)C2)ncc1C(F)(F)F.Cc1noc(C)c1-c1ccc2c(n1)CC=C2c1nc(N[C@H]2CCC[C@@H]2N2CC[C@H](F)C2)ncc1C(F)(F)F.Cc1noc(C)c1-c1ccc2c(n1)CC=C2c1nc(N[C@H]2CCC[C@@H]2NCCO)ncc1C(F)(F)F.Cc1noc(C)c1-c1ccc2c(n1)CC=C2c1nc(N[C@H]2CCC[C@H]2N2CC(F)C2)ncc1C(F)(F)F.Cc1noc(C)c1-c1ccc2c(n1)CC=C2c1nc(N[C@H]2CC[C@@H]2N2CCCC2)ncc1C(F)(F)F
InChIInChI=1S/C28H31F3N6O2.2C27H28F4N6O.C26H26F5N5O.2C26H26F4N6O.C26H27F4N5O.C26H29F3N6O2.2C26H27F3N6O.C25H27F3N6O2.C25H27F3N6O/c1-15-25(16(2)39-36-15)23-10-7-18-19(8-9-21(18)33-23)26-20(28(29,30)31)13-32-27(35-26)34-22-5-4-6-24(22)37-12-11-17(14-37)38-3;2*1-14-24(15(2)38-36-14)22-9-6-17-18(7-8-20(17)33-22)25-19(27(29,30)31)12-32-26(35-25)34-21-4-3-5-23(21)37-11-10-16(28)13-37;1-13-23(14(2)37-36-13)21-10-7-16-17(8-9-20(16)33-21)24-18(26(29,30)31)12-32-25(35-24)34-19-5-3-4-15(19)6-11-22(27)28;2*1-13-23(14(2)37-35-13)21-9-6-16-17(7-8-19(16)32-21)24-18(26(28,29)30)10-31-25(34-24)33-20-4-3-5-22(20)36-11-15(27)12-36;1-14-23(15(2)36-35-14)22-11-8-17-18(9-10-21(17)32-22)24-19(26(28,29)30)13-31-25(34-24)33-20-7-3-5-16(20)6-4-12-27;1-14-23(15(2)37-35-14)22-10-7-16-17(8-9-19(16)32-22)24-18(26(27,28)29)13-31-25(34-24)33-21-6-4-5-20(21)30-11-12-36-3;1-14-23(15(2)36-34-14)21-10-7-16-17(8-9-19(16)31-21)24-18(26(27,28)29)13-30-25(33-24)32-20-5-3-6-22(20)35-11-4-12-35;1-14-23(15(2)36-34-14)21-8-5-16-17(6-7-19(16)31-21)24-18(26(27,28)29)13-30-25(33-24)32-20-9-10-22(20)35-11-3-4-12-35;1-13-22(14(2)36-34-13)21-9-6-15-16(7-8-18(15)31-21)23-17(25(26,27)28)12-30-24(33-23)32-20-5-3-4-19(20)29-10-11-35;1-4-29-19-6-5-7-20(19)32-24-30-12-17(25(26,27)28)23(33-24)16-9-10-18-15(16)8-11-21(31-18)22-13(2)34-35-14(22)3/h7-8,10,13,17,22,24H,4-6,9,11-12,14H2,1-3H3,(H,32,34,35);2*6-7,9,12,16,21,23H,3-5,8,10-11,13H2,1-2H3,(H,32,34,35);7-8,10,12,15,19,22H,3-6,9,11H2,1-2H3,(H,32,34,35);2*6-7,9-10,15,20,22H,3-5,8,11-12H2,1-2H3,(H,31,33,34);8-9,11,13,16,20H,3-7,10,12H2,1-2H3,(H,31,33,34);7-8,10,13,20-21,30H,4-6,9,11-12H2,1-3H3,(H,31,33,34);7-8,10,13,20,22H,3-6,9,11-12H2,1-2H3,(H,30,32,33);5-6,8,13,20,22H,3-4,7,9-12H2,1-2H3,(H,30,32,33);6-7,9,12,19-20,29,35H,3-5,8,10-11H2,1-2H3,(H,30,32,33);8-9,11-12,19-20,29H,4-7,10H2,1-3H3,(H,30,32,33)/t17?,22-,24-;16-,21+,23+;16-,21-,23-;15-,19+;20-,22+;20-,22-;16-,20+;20-,21-;2*20-,22-;2*19-,20-/m010100100000/s1
InChIKeyMNNSLBGIAOFRPF-DELJOJDFSA-N
MW6140.48 g/mol
LogP64.04
Rot. Bonds71

About N-[(1S,2S)-2-(azetidin-1-yl)cyclopentyl]-4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-5-(trifluoromethyl)pyrimidin-2-amine;N-[(1S,2R)-2-(3,3-difluoropropyl)cyclopentyl]-4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-5-(trifluoromethyl)pyrimidin-2-amine;4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-N-[(1S,2S)-2-(3-fluoroazetidin-1-yl)cyclopentyl]-5-(trifluoromethyl)pyrimidin-2-amine;4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-N-[(1S,2R)-2-(3-fluoroazetidin-1-yl)cyclopentyl]-5-(trifluoromethyl)pyrimidin-2-amine;4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-N-[(1S,2R)-2-(3-fluoropropyl)cyclopentyl]-5-(trifluoromethyl)pyrimidin-2-amine;4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-N-[(1S,2S)-2-[(3S)-3-fluoropyrrolidin-1-yl]cyclopentyl]-5-(trifluoromethyl)pyrimidin-2-amine;4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-N-[(1S,2S)-2-[(3R)-3-fluoropyrrolidin-1-yl]cyclopentyl]-5-(trifluoromethyl)pyrimidin-2-amine;4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-N-[(1S,2S)-2-(3-methoxypyrrolidin-1-yl)cyclopentyl]-5-(trifluoromethyl)pyrimidin-2-amine;4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-N-[(1S,2S)-2-pyrrolidin-1-ylcyclobutyl]-5-(trifluoromethyl)pyrimidin-2-amine;2-[[(1S,2S)-2-[[4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-5-(trifluoromethyl)pyrimidin-2-yl]amino]cyclopentyl]amino]ethanol;trans-(1S,2S)-1-N-[4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-5-(trifluoromethyl)pyrimidin-2-yl]-2-N-ethylcyclopentane-1,2-diamine;trans-(1S,2S)-1-N-[4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-5-(trifluoromethyl)pyrimidin-2-yl]-2-N-(2-methoxyethyl)cyclopentane-1,2-diamine

N-[(1S,2S)-2-(azetidin-1-yl)cyclopentyl]-4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-5-(trifluoromethyl)pyrimidin-2-amine;N-[(1S,2R)-2-(3,3-difluoropropyl)cyclopentyl]-4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-5-(trifluoromethyl)pyrimidin-2-amine;4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-N-[(1S,2S)-2-(3-fluoroazetidin-1-yl)cyclopentyl]-5-(trifluoromethyl)pyrimidin-2-amine;4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-N-[(1S,2R)-2-(3-fluoroazetidin-1-yl)cyclopentyl]-5-(trifluoromethyl)pyrimidin-2-amine;4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-N-[(1S,2R)-2-(3-fluoropropyl)cyclopentyl]-5-(trifluoromethyl)pyrimidin-2-amine;4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-N-[(1S,2S)-2-[(3S)-3-fluoropyrrolidin-1-yl]cyclopentyl]-5-(trifluoromethyl)pyrimidin-2-amine;4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-N-[(1S,2S)-2-[(3R)-3-fluoropyrrolidin-1-yl]cyclopentyl]-5-(trifluoromethyl)pyrimidin-2-amine;4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-N-[(1S,2S)-2-(3-methoxypyrrolidin-1-yl)cyclopentyl]-5-(trifluoromethyl)pyrimidin-2-amine;4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-N-[(1S,2S)-2-pyrrolidin-1-ylcyclobutyl]-5-(trifluoromethyl)pyrimidin-2-amine;2-[[(1S,2S)-2-[[4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-5-(trifluoromethyl)pyrimidin-2-yl]amino]cyclopentyl]amino]ethanol;trans-(1S,2S)-1-N-[4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-5-(trifluoromethyl)pyrimidin-2-yl]-2-N-ethylcyclopentane-1,2-diamine;trans-(1S,2S)-1-N-[4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-5-(trifluoromethyl)pyrimidin-2-yl]-2-N-(2-methoxyethyl)cyclopentane-1,2-diamine (PubChem CID 163779613) has the molecular formula C314H329F43N70O15 and a molecular weight of 6140.48 g/mol. Its IUPAC name is N-[(1S,2S)-2-(azetidin-1-yl)cyclopentyl]-4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-5-(trifluoromethyl)pyrimidin-2-amine;N-[(1S,2R)-2-(3,3-difluoropropyl)cyclopentyl]-4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-5-(trifluoromethyl)pyrimidin-2-amine;4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-N-[(1S,2S)-2-(3-fluoroazetidin-1-yl)cyclopentyl]-5-(trifluoromethyl)pyrimidin-2-amine;4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-N-[(1S,2R)-2-(3-fluoroazetidin-1-yl)cyclopentyl]-5-(trifluoromethyl)pyrimidin-2-amine;4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-N-[(1S,2R)-2-(3-fluoropropyl)cyclopentyl]-5-(trifluoromethyl)pyrimidin-2-amine;4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-N-[(1S,2S)-2-[(3S)-3-fluoropyrrolidin-1-yl]cyclopentyl]-5-(trifluoromethyl)pyrimidin-2-amine;4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-N-[(1S,2S)-2-[(3R)-3-fluoropyrrolidin-1-yl]cyclopentyl]-5-(trifluoromethyl)pyrimidin-2-amine;4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-N-[(1S,2S)-2-(3-methoxypyrrolidin-1-yl)cyclopentyl]-5-(trifluoromethyl)pyrimidin-2-amine;4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-N-[(1S,2S)-2-pyrrolidin-1-ylcyclobutyl]-5-(trifluoromethyl)pyrimidin-2-amine;2-[[(1S,2S)-2-[[4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-5-(trifluoromethyl)pyrimidin-2-yl]amino]cyclopentyl]amino]ethanol;trans-(1S,2S)-1-N-[4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-5-(trifluoromethyl)pyrimidin-2-yl]-2-N-ethylcyclopentane-1,2-diamine;trans-(1S,2S)-1-N-[4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-5-(trifluoromethyl)pyrimidin-2-yl]-2-N-(2-methoxyethyl)cyclopentane-1,2-diamine.

Molecular Properties

Compound NameN-[(1S,2S)-2-(azetidin-1-yl)cyclopentyl]-4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-5-(trifluoromethyl)pyrimidin-2-amine;N-[(1S,2R)-2-(3,3-difluoropropyl)cyclopentyl]-4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-5-(trifluoromethyl)pyrimidin-2-amine;4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-N-[(1S,2S)-2-(3-fluoroazetidin-1-yl)cyclopentyl]-5-(trifluoromethyl)pyrimidin-2-amine;4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-N-[(1S,2R)-2-(3-fluoroazetidin-1-yl)cyclopentyl]-5-(trifluoromethyl)pyrimidin-2-amine;4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-N-[(1S,2R)-2-(3-fluoropropyl)cyclopentyl]-5-(trifluoromethyl)pyrimidin-2-amine;4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-N-[(1S,2S)-2-[(3S)-3-fluoropyrrolidin-1-yl]cyclopentyl]-5-(trifluoromethyl)pyrimidin-2-amine;4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-N-[(1S,2S)-2-[(3R)-3-fluoropyrrolidin-1-yl]cyclopentyl]-5-(trifluoromethyl)pyrimidin-2-amine;4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-N-[(1S,2S)-2-(3-methoxypyrrolidin-1-yl)cyclopentyl]-5-(trifluoromethyl)pyrimidin-2-amine;4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-N-[(1S,2S)-2-pyrrolidin-1-ylcyclobutyl]-5-(trifluoromethyl)pyrimidin-2-amine;2-[[(1S,2S)-2-[[4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-5-(trifluoromethyl)pyrimidin-2-yl]amino]cyclopentyl]amino]ethanol;trans-(1S,2S)-1-N-[4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-5-(trifluoromethyl)pyrimidin-2-yl]-2-N-ethylcyclopentane-1,2-diamine;trans-(1S,2S)-1-N-[4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-5-(trifluoromethyl)pyrimidin-2-yl]-2-N-(2-methoxyethyl)cyclopentane-1,2-diamine
PubChem CID163779613
Molecular FormulaC314H329F43N70O15
Molecular Weight6140.48 g/mol
Exact Mass6136.64
IUPAC NameN-[(1S,2S)-2-(azetidin-1-yl)cyclopentyl]-4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-5-(trifluoromethyl)pyrimidin-2-amine;N-[(1S,2R)-2-(3,3-difluoropropyl)cyclopentyl]-4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-5-(trifluoromethyl)pyrimidin-2-amine;4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-N-[(1S,2S)-2-(3-fluoroazetidin-1-yl)cyclopentyl]-5-(trifluoromethyl)pyrimidin-2-amine;4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-N-[(1S,2R)-2-(3-fluoroazetidin-1-yl)cyclopentyl]-5-(trifluoromethyl)pyrimidin-2-amine;4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-N-[(1S,2R)-2-(3-fluoropropyl)cyclopentyl]-5-(trifluoromethyl)pyrimidin-2-amine;4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-N-[(1S,2S)-2-[(3S)-3-fluoropyrrolidin-1-yl]cyclopentyl]-5-(trifluoromethyl)pyrimidin-2-amine;4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-N-[(1S,2S)-2-[(3R)-3-fluoropyrrolidin-1-yl]cyclopentyl]-5-(trifluoromethyl)pyrimidin-2-amine;4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-N-[(1S,2S)-2-(3-methoxypyrrolidin-1-yl)cyclopentyl]-5-(trifluoromethyl)pyrimidin-2-amine;4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-N-[(1S,2S)-2-pyrrolidin-1-ylcyclobutyl]-5-(trifluoromethyl)pyrimidin-2-amine;2-[[(1S,2S)-2-[[4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-5-(trifluoromethyl)pyrimidin-2-yl]amino]cyclopentyl]amino]ethanol;trans-(1S,2S)-1-N-[4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-5-(trifluoromethyl)pyrimidin-2-yl]-2-N-ethylcyclopentane-1,2-diamine;trans-(1S,2S)-1-N-[4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-5-(trifluoromethyl)pyrimidin-2-yl]-2-N-(2-methoxyethyl)cyclopentane-1,2-diamine
SMILESCCN[C@H]1CCC[C@@H]1Nc1ncc(C(F)(F)F)c(C2=CCc3nc(-c4c(C)noc4C)ccc32)n1.COC1CCN([C@H]2CCC[C@@H]2Nc2ncc(C(F)(F)F)c(C3=CCc4nc(-c5c(C)noc5C)ccc43)n2)C1.COCCN[C@H]1CCC[C@@H]1Nc1ncc(C(F)(F)F)c(C2=CCc3nc(-c4c(C)noc4C)ccc32)n1.Cc1noc(C)c1-c1ccc2c(n1)CC=C2c1nc(N[C@H]2CCC[C@@H]2CCC(F)F)ncc1C(F)(F)F.Cc1noc(C)c1-c1ccc2c(n1)CC=C2c1nc(N[C@H]2CCC[C@@H]2CCCF)ncc1C(F)(F)F.Cc1noc(C)c1-c1ccc2c(n1)CC=C2c1nc(N[C@H]2CCC[C@@H]2N2CC(F)C2)ncc1C(F)(F)F.Cc1noc(C)c1-c1ccc2c(n1)CC=C2c1nc(N[C@H]2CCC[C@@H]2N2CCC2)ncc1C(F)(F)F.Cc1noc(C)c1-c1ccc2c(n1)CC=C2c1nc(N[C@H]2CCC[C@@H]2N2CC[C@@H](F)C2)ncc1C(F)(F)F.Cc1noc(C)c1-c1ccc2c(n1)CC=C2c1nc(N[C@H]2CCC[C@@H]2N2CC[C@H](F)C2)ncc1C(F)(F)F.Cc1noc(C)c1-c1ccc2c(n1)CC=C2c1nc(N[C@H]2CCC[C@@H]2NCCO)ncc1C(F)(F)F.Cc1noc(C)c1-c1ccc2c(n1)CC=C2c1nc(N[C@H]2CCC[C@H]2N2CC(F)C2)ncc1C(F)(F)F.Cc1noc(C)c1-c1ccc2c(n1)CC=C2c1nc(N[C@H]2CC[C@@H]2N2CCCC2)ncc1C(F)(F)F
InChIInChI=1S/C28H31F3N6O2.2C27H28F4N6O.C26H26F5N5O.2C26H26F4N6O.C26H27F4N5O.C26H29F3N6O2.2C26H27F3N6O.C25H27F3N6O2.C25H27F3N6O/c1-15-25(16(2)39-36-15)23-10-7-18-19(8-9-21(18)33-23)26-20(28(29,30)31)13-32-27(35-26)34-22-5-4-6-24(22)37-12-11-17(14-37)38-3;2*1-14-24(15(2)38-36-14)22-9-6-17-18(7-8-20(17)33-22)25-19(27(29,30)31)12-32-26(35-25)34-21-4-3-5-23(21)37-11-10-16(28)13-37;1-13-23(14(2)37-36-13)21-10-7-16-17(8-9-20(16)33-21)24-18(26(29,30)31)12-32-25(35-24)34-19-5-3-4-15(19)6-11-22(27)28;2*1-13-23(14(2)37-35-13)21-9-6-16-17(7-8-19(16)32-21)24-18(26(28,29)30)10-31-25(34-24)33-20-4-3-5-22(20)36-11-15(27)12-36;1-14-23(15(2)36-35-14)22-11-8-17-18(9-10-21(17)32-22)24-19(26(28,29)30)13-31-25(34-24)33-20-7-3-5-16(20)6-4-12-27;1-14-23(15(2)37-35-14)22-10-7-16-17(8-9-19(16)32-22)24-18(26(27,28)29)13-31-25(34-24)33-21-6-4-5-20(21)30-11-12-36-3;1-14-23(15(2)36-34-14)21-10-7-16-17(8-9-19(16)31-21)24-18(26(27,28)29)13-30-25(33-24)32-20-5-3-6-22(20)35-11-4-12-35;1-14-23(15(2)36-34-14)21-8-5-16-17(6-7-19(16)31-21)24-18(26(27,28)29)13-30-25(33-24)32-20-9-10-22(20)35-11-3-4-12-35;1-13-22(14(2)36-34-13)21-9-6-15-16(7-8-18(15)31-21)23-17(25(26,27)28)12-30-24(33-23)32-20-5-3-4-19(20)29-10-11-35;1-4-29-19-6-5-7-20(19)32-24-30-12-17(25(26,27)28)23(33-24)16-9-10-18-15(16)8-11-21(31-18)22-13(2)34-35-14(22)3/h7-8,10,13,17,22,24H,4-6,9,11-12,14H2,1-3H3,(H,32,34,35);2*6-7,9,12,16,21,23H,3-5,8,10-11,13H2,1-2H3,(H,32,34,35);7-8,10,12,15,19,22H,3-6,9,11H2,1-2H3,(H,32,34,35);2*6-7,9-10,15,20,22H,3-5,8,11-12H2,1-2H3,(H,31,33,34);8-9,11,13,16,20H,3-7,10,12H2,1-2H3,(H,31,33,34);7-8,10,13,20-21,30H,4-6,9,11-12H2,1-3H3,(H,31,33,34);7-8,10,13,20,22H,3-6,9,11-12H2,1-2H3,(H,30,32,33);5-6,8,13,20,22H,3-4,7,9-12H2,1-2H3,(H,30,32,33);6-7,9,12,19-20,29,35H,3-5,8,10-11H2,1-2H3,(H,30,32,33);8-9,11-12,19-20,29H,4-7,10H2,1-3H3,(H,30,32,33)/t17?,22-,24-;16-,21+,23+;16-,21-,23-;15-,19+;20-,22+;20-,22-;16-,20+;20-,21-;2*20-,22-;2*19-,20-/m010100100000/s1
InChIKeyMNNSLBGIAOFRPF-DELJOJDFSA-N
XLogP64.04
TPSA1018.22 Ų
H-Bond Donors16
H-Bond Acceptors85
Rotatable Bonds71
Heavy Atoms442
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5006140.48
LogP ≤ 564.04
H-Bond Donors ≤ 516
H-Bond Acceptors ≤ 1085

Analyze N-[(1S,2S)-2-(azetidin-1-yl)cyclopentyl]-4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-5-(trifluoromethyl)pyrimidin-2-amine;N-[(1S,2R)-2-(3,3-difluoropropyl)cyclopentyl]-4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-5-(trifluoromethyl)pyrimidin-2-amine;4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-N-[(1S,2S)-2-(3-fluoroazetidin-1-yl)cyclopentyl]-5-(trifluoromethyl)pyrimidin-2-amine;4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-N-[(1S,2R)-2-(3-fluoroazetidin-1-yl)cyclopentyl]-5-(trifluoromethyl)pyrimidin-2-amine;4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-N-[(1S,2R)-2-(3-fluoropropyl)cyclopentyl]-5-(trifluoromethyl)pyrimidin-2-amine;4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-N-[(1S,2S)-2-[(3S)-3-fluoropyrrolidin-1-yl]cyclopentyl]-5-(trifluoromethyl)pyrimidin-2-amine;4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-N-[(1S,2S)-2-[(3R)-3-fluoropyrrolidin-1-yl]cyclopentyl]-5-(trifluoromethyl)pyrimidin-2-amine;4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-N-[(1S,2S)-2-(3-methoxypyrrolidin-1-yl)cyclopentyl]-5-(trifluoromethyl)pyrimidin-2-amine;4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-N-[(1S,2S)-2-pyrrolidin-1-ylcyclobutyl]-5-(trifluoromethyl)pyrimidin-2-amine;2-[[(1S,2S)-2-[[4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-5-(trifluoromethyl)pyrimidin-2-yl]amino]cyclopentyl]amino]ethanol;trans-(1S,2S)-1-N-[4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-5-(trifluoromethyl)pyrimidin-2-yl]-2-N-ethylcyclopentane-1,2-diamine;trans-(1S,2S)-1-N-[4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-5-(trifluoromethyl)pyrimidin-2-yl]-2-N-(2-methoxyethyl)cyclopentane-1,2-diamine with MolForge

Explore ADMET properties, 3D molecular structure, drug-likeness score, and discover similar compounds using our AI-powered platform.

Launch Full Analysis

Frequently Asked Questions

What is the IUPAC name of N-[(1S,2S)-2-(azetidin-1-yl)cyclopentyl]-4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-5-(trifluoromethyl)pyrimidin-2-amine;N-[(1S,2R)-2-(3,3-difluoropropyl)cyclopentyl]-4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-5-(trifluoromethyl)pyrimidin-2-amine;4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-N-[(1S,2S)-2-(3-fluoroazetidin-1-yl)cyclopentyl]-5-(trifluoromethyl)pyrimidin-2-amine;4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-N-[(1S,2R)-2-(3-fluoroazetidin-1-yl)cyclopentyl]-5-(trifluoromethyl)pyrimidin-2-amine;4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-N-[(1S,2R)-2-(3-fluoropropyl)cyclopentyl]-5-(trifluoromethyl)pyrimidin-2-amine;4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-N-[(1S,2S)-2-[(3S)-3-fluoropyrrolidin-1-yl]cyclopentyl]-5-(trifluoromethyl)pyrimidin-2-amine;4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-N-[(1S,2S)-2-[(3R)-3-fluoropyrrolidin-1-yl]cyclopentyl]-5-(trifluoromethyl)pyrimidin-2-amine;4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-N-[(1S,2S)-2-(3-methoxypyrrolidin-1-yl)cyclopentyl]-5-(trifluoromethyl)pyrimidin-2-amine;4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-N-[(1S,2S)-2-pyrrolidin-1-ylcyclobutyl]-5-(trifluoromethyl)pyrimidin-2-amine;2-[[(1S,2S)-2-[[4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-5-(trifluoromethyl)pyrimidin-2-yl]amino]cyclopentyl]amino]ethanol;trans-(1S,2S)-1-N-[4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-5-(trifluoromethyl)pyrimidin-2-yl]-2-N-ethylcyclopentane-1,2-diamine;trans-(1S,2S)-1-N-[4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-5-(trifluoromethyl)pyrimidin-2-yl]-2-N-(2-methoxyethyl)cyclopentane-1,2-diamine?
The IUPAC name of N-[(1S,2S)-2-(azetidin-1-yl)cyclopentyl]-4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-5-(trifluoromethyl)pyrimidin-2-amine;N-[(1S,2R)-2-(3,3-difluoropropyl)cyclopentyl]-4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-5-(trifluoromethyl)pyrimidin-2-amine;4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-N-[(1S,2S)-2-(3-fluoroazetidin-1-yl)cyclopentyl]-5-(trifluoromethyl)pyrimidin-2-amine;4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-N-[(1S,2R)-2-(3-fluoroazetidin-1-yl)cyclopentyl]-5-(trifluoromethyl)pyrimidin-2-amine;4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-N-[(1S,2R)-2-(3-fluoropropyl)cyclopentyl]-5-(trifluoromethyl)pyrimidin-2-amine;4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-N-[(1S,2S)-2-[(3S)-3-fluoropyrrolidin-1-yl]cyclopentyl]-5-(trifluoromethyl)pyrimidin-2-amine;4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-N-[(1S,2S)-2-[(3R)-3-fluoropyrrolidin-1-yl]cyclopentyl]-5-(trifluoromethyl)pyrimidin-2-amine;4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-N-[(1S,2S)-2-(3-methoxypyrrolidin-1-yl)cyclopentyl]-5-(trifluoromethyl)pyrimidin-2-amine;4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-N-[(1S,2S)-2-pyrrolidin-1-ylcyclobutyl]-5-(trifluoromethyl)pyrimidin-2-amine;2-[[(1S,2S)-2-[[4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-5-(trifluoromethyl)pyrimidin-2-yl]amino]cyclopentyl]amino]ethanol;trans-(1S,2S)-1-N-[4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-5-(trifluoromethyl)pyrimidin-2-yl]-2-N-ethylcyclopentane-1,2-diamine;trans-(1S,2S)-1-N-[4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-5-(trifluoromethyl)pyrimidin-2-yl]-2-N-(2-methoxyethyl)cyclopentane-1,2-diamine (CID 163779613) is N-[(1S,2S)-2-(azetidin-1-yl)cyclopentyl]-4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-5-(trifluoromethyl)pyrimidin-2-amine;N-[(1S,2R)-2-(3,3-difluoropropyl)cyclopentyl]-4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-5-(trifluoromethyl)pyrimidin-2-amine;4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-N-[(1S,2S)-2-(3-fluoroazetidin-1-yl)cyclopentyl]-5-(trifluoromethyl)pyrimidin-2-amine;4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-N-[(1S,2R)-2-(3-fluoroazetidin-1-yl)cyclopentyl]-5-(trifluoromethyl)pyrimidin-2-amine;4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-N-[(1S,2R)-2-(3-fluoropropyl)cyclopentyl]-5-(trifluoromethyl)pyrimidin-2-amine;4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-N-[(1S,2S)-2-[(3S)-3-fluoropyrrolidin-1-yl]cyclopentyl]-5-(trifluoromethyl)pyrimidin-2-amine;4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-N-[(1S,2S)-2-[(3R)-3-fluoropyrrolidin-1-yl]cyclopentyl]-5-(trifluoromethyl)pyrimidin-2-amine;4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-N-[(1S,2S)-2-(3-methoxypyrrolidin-1-yl)cyclopentyl]-5-(trifluoromethyl)pyrimidin-2-amine;4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-N-[(1S,2S)-2-pyrrolidin-1-ylcyclobutyl]-5-(trifluoromethyl)pyrimidin-2-amine;2-[[(1S,2S)-2-[[4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-5-(trifluoromethyl)pyrimidin-2-yl]amino]cyclopentyl]amino]ethanol;trans-(1S,2S)-1-N-[4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-5-(trifluoromethyl)pyrimidin-2-yl]-2-N-ethylcyclopentane-1,2-diamine;trans-(1S,2S)-1-N-[4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-5-(trifluoromethyl)pyrimidin-2-yl]-2-N-(2-methoxyethyl)cyclopentane-1,2-diamine.
What is the SMILES notation for N-[(1S,2S)-2-(azetidin-1-yl)cyclopentyl]-4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-5-(trifluoromethyl)pyrimidin-2-amine;N-[(1S,2R)-2-(3,3-difluoropropyl)cyclopentyl]-4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-5-(trifluoromethyl)pyrimidin-2-amine;4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-N-[(1S,2S)-2-(3-fluoroazetidin-1-yl)cyclopentyl]-5-(trifluoromethyl)pyrimidin-2-amine;4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-N-[(1S,2R)-2-(3-fluoroazetidin-1-yl)cyclopentyl]-5-(trifluoromethyl)pyrimidin-2-amine;4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-N-[(1S,2R)-2-(3-fluoropropyl)cyclopentyl]-5-(trifluoromethyl)pyrimidin-2-amine;4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-N-[(1S,2S)-2-[(3S)-3-fluoropyrrolidin-1-yl]cyclopentyl]-5-(trifluoromethyl)pyrimidin-2-amine;4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-N-[(1S,2S)-2-[(3R)-3-fluoropyrrolidin-1-yl]cyclopentyl]-5-(trifluoromethyl)pyrimidin-2-amine;4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-N-[(1S,2S)-2-(3-methoxypyrrolidin-1-yl)cyclopentyl]-5-(trifluoromethyl)pyrimidin-2-amine;4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-N-[(1S,2S)-2-pyrrolidin-1-ylcyclobutyl]-5-(trifluoromethyl)pyrimidin-2-amine;2-[[(1S,2S)-2-[[4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-5-(trifluoromethyl)pyrimidin-2-yl]amino]cyclopentyl]amino]ethanol;trans-(1S,2S)-1-N-[4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-5-(trifluoromethyl)pyrimidin-2-yl]-2-N-ethylcyclopentane-1,2-diamine;trans-(1S,2S)-1-N-[4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-5-(trifluoromethyl)pyrimidin-2-yl]-2-N-(2-methoxyethyl)cyclopentane-1,2-diamine?
The canonical SMILES for N-[(1S,2S)-2-(azetidin-1-yl)cyclopentyl]-4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-5-(trifluoromethyl)pyrimidin-2-amine;N-[(1S,2R)-2-(3,3-difluoropropyl)cyclopentyl]-4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-5-(trifluoromethyl)pyrimidin-2-amine;4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-N-[(1S,2S)-2-(3-fluoroazetidin-1-yl)cyclopentyl]-5-(trifluoromethyl)pyrimidin-2-amine;4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-N-[(1S,2R)-2-(3-fluoroazetidin-1-yl)cyclopentyl]-5-(trifluoromethyl)pyrimidin-2-amine;4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-N-[(1S,2R)-2-(3-fluoropropyl)cyclopentyl]-5-(trifluoromethyl)pyrimidin-2-amine;4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-N-[(1S,2S)-2-[(3S)-3-fluoropyrrolidin-1-yl]cyclopentyl]-5-(trifluoromethyl)pyrimidin-2-amine;4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-N-[(1S,2S)-2-[(3R)-3-fluoropyrrolidin-1-yl]cyclopentyl]-5-(trifluoromethyl)pyrimidin-2-amine;4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-N-[(1S,2S)-2-(3-methoxypyrrolidin-1-yl)cyclopentyl]-5-(trifluoromethyl)pyrimidin-2-amine;4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-N-[(1S,2S)-2-pyrrolidin-1-ylcyclobutyl]-5-(trifluoromethyl)pyrimidin-2-amine;2-[[(1S,2S)-2-[[4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-5-(trifluoromethyl)pyrimidin-2-yl]amino]cyclopentyl]amino]ethanol;trans-(1S,2S)-1-N-[4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-5-(trifluoromethyl)pyrimidin-2-yl]-2-N-ethylcyclopentane-1,2-diamine;trans-(1S,2S)-1-N-[4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-5-(trifluoromethyl)pyrimidin-2-yl]-2-N-(2-methoxyethyl)cyclopentane-1,2-diamine is CCN[C@H]1CCC[C@@H]1Nc1ncc(C(F)(F)F)c(C2=CCc3nc(-c4c(C)noc4C)ccc32)n1.COC1CCN([C@H]2CCC[C@@H]2Nc2ncc(C(F)(F)F)c(C3=CCc4nc(-c5c(C)noc5C)ccc43)n2)C1.COCCN[C@H]1CCC[C@@H]1Nc1ncc(C(F)(F)F)c(C2=CCc3nc(-c4c(C)noc4C)ccc32)n1.Cc1noc(C)c1-c1ccc2c(n1)CC=C2c1nc(N[C@H]2CCC[C@@H]2CCC(F)F)ncc1C(F)(F)F.Cc1noc(C)c1-c1ccc2c(n1)CC=C2c1nc(N[C@H]2CCC[C@@H]2CCCF)ncc1C(F)(F)F.Cc1noc(C)c1-c1ccc2c(n1)CC=C2c1nc(N[C@H]2CCC[C@@H]2N2CC(F)C2)ncc1C(F)(F)F.Cc1noc(C)c1-c1ccc2c(n1)CC=C2c1nc(N[C@H]2CCC[C@@H]2N2CCC2)ncc1C(F)(F)F.Cc1noc(C)c1-c1ccc2c(n1)CC=C2c1nc(N[C@H]2CCC[C@@H]2N2CC[C@@H](F)C2)ncc1C(F)(F)F.Cc1noc(C)c1-c1ccc2c(n1)CC=C2c1nc(N[C@H]2CCC[C@@H]2N2CC[C@H](F)C2)ncc1C(F)(F)F.Cc1noc(C)c1-c1ccc2c(n1)CC=C2c1nc(N[C@H]2CCC[C@@H]2NCCO)ncc1C(F)(F)F.Cc1noc(C)c1-c1ccc2c(n1)CC=C2c1nc(N[C@H]2CCC[C@H]2N2CC(F)C2)ncc1C(F)(F)F.Cc1noc(C)c1-c1ccc2c(n1)CC=C2c1nc(N[C@H]2CC[C@@H]2N2CCCC2)ncc1C(F)(F)F.
What is the InChIKey of N-[(1S,2S)-2-(azetidin-1-yl)cyclopentyl]-4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-5-(trifluoromethyl)pyrimidin-2-amine;N-[(1S,2R)-2-(3,3-difluoropropyl)cyclopentyl]-4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-5-(trifluoromethyl)pyrimidin-2-amine;4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-N-[(1S,2S)-2-(3-fluoroazetidin-1-yl)cyclopentyl]-5-(trifluoromethyl)pyrimidin-2-amine;4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-N-[(1S,2R)-2-(3-fluoroazetidin-1-yl)cyclopentyl]-5-(trifluoromethyl)pyrimidin-2-amine;4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-N-[(1S,2R)-2-(3-fluoropropyl)cyclopentyl]-5-(trifluoromethyl)pyrimidin-2-amine;4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-N-[(1S,2S)-2-[(3S)-3-fluoropyrrolidin-1-yl]cyclopentyl]-5-(trifluoromethyl)pyrimidin-2-amine;4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-N-[(1S,2S)-2-[(3R)-3-fluoropyrrolidin-1-yl]cyclopentyl]-5-(trifluoromethyl)pyrimidin-2-amine;4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-N-[(1S,2S)-2-(3-methoxypyrrolidin-1-yl)cyclopentyl]-5-(trifluoromethyl)pyrimidin-2-amine;4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-N-[(1S,2S)-2-pyrrolidin-1-ylcyclobutyl]-5-(trifluoromethyl)pyrimidin-2-amine;2-[[(1S,2S)-2-[[4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-5-(trifluoromethyl)pyrimidin-2-yl]amino]cyclopentyl]amino]ethanol;trans-(1S,2S)-1-N-[4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-5-(trifluoromethyl)pyrimidin-2-yl]-2-N-ethylcyclopentane-1,2-diamine;trans-(1S,2S)-1-N-[4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-5-(trifluoromethyl)pyrimidin-2-yl]-2-N-(2-methoxyethyl)cyclopentane-1,2-diamine?
The InChIKey is MNNSLBGIAOFRPF-DELJOJDFSA-N. The full InChI is InChI=1S/C28H31F3N6O2.2C27H28F4N6O.C26H26F5N5O.2C26H26F4N6O.C26H27F4N5O.C26H29F3N6O2.2C26H27F3N6O.C25H27F3N6O2.C25H27F3N6O/c1-15-25(16(2)39-36-15)23-10-7-18-19(8-9-21(18)33-23)26-20(28(29,30)31)13-32-27(35-26)34-22-5-4-6-24(22)37-12-11-17(14-37)38-3;2*1-14-24(15(2)38-36-14)22-9-6-17-18(7-8-20(17)33-22)25-19(27(29,30)31)12-32-26(35-25)34-21-4-3-5-23(21)37-11-10-16(28)13-37;1-13-23(14(2)37-36-13)21-10-7-16-17(8-9-20(16)33-21)24-18(26(29,30)31)12-32-25(35-24)34-19-5-3-4-15(19)6-11-22(27)28;2*1-13-23(14(2)37-35-13)21-9-6-16-17(7-8-19(16)32-21)24-18(26(28,29)30)10-31-25(34-24)33-20-4-3-5-22(20)36-11-15(27)12-36;1-14-23(15(2)36-35-14)22-11-8-17-18(9-10-21(17)32-22)24-19(26(28,29)30)13-31-25(34-24)33-20-7-3-5-16(20)6-4-12-27;1-14-23(15(2)37-35-14)22-10-7-16-17(8-9-19(16)32-22)24-18(26(27,28)29)13-31-25(34-24)33-21-6-4-5-20(21)30-11-12-36-3;1-14-23(15(2)36-34-14)21-10-7-16-17(8-9-19(16)31-21)24-18(26(27,28)29)13-30-25(33-24)32-20-5-3-6-22(20)35-11-4-12-35;1-14-23(15(2)36-34-14)21-8-5-16-17(6-7-19(16)31-21)24-18(26(27,28)29)13-30-25(33-24)32-20-9-10-22(20)35-11-3-4-12-35;1-13-22(14(2)36-34-13)21-9-6-15-16(7-8-18(15)31-21)23-17(25(26,27)28)12-30-24(33-23)32-20-5-3-4-19(20)29-10-11-35;1-4-29-19-6-5-7-20(19)32-24-30-12-17(25(26,27)28)23(33-24)16-9-10-18-15(16)8-11-21(31-18)22-13(2)34-35-14(22)3/h7-8,10,13,17,22,24H,4-6,9,11-12,14H2,1-3H3,(H,32,34,35);2*6-7,9,12,16,21,23H,3-5,8,10-11,13H2,1-2H3,(H,32,34,35);7-8,10,12,15,19,22H,3-6,9,11H2,1-2H3,(H,32,34,35);2*6-7,9-10,15,20,22H,3-5,8,11-12H2,1-2H3,(H,31,33,34);8-9,11,13,16,20H,3-7,10,12H2,1-2H3,(H,31,33,34);7-8,10,13,20-21,30H,4-6,9,11-12H2,1-3H3,(H,31,33,34);7-8,10,13,20,22H,3-6,9,11-12H2,1-2H3,(H,30,32,33);5-6,8,13,20,22H,3-4,7,9-12H2,1-2H3,(H,30,32,33);6-7,9,12,19-20,29,35H,3-5,8,10-11H2,1-2H3,(H,30,32,33);8-9,11-12,19-20,29H,4-7,10H2,1-3H3,(H,30,32,33)/t17?,22-,24-;16-,21+,23+;16-,21-,23-;15-,19+;20-,22+;20-,22-;16-,20+;20-,21-;2*20-,22-;2*19-,20-/m010100100000/s1.
What are the key properties of N-[(1S,2S)-2-(azetidin-1-yl)cyclopentyl]-4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-5-(trifluoromethyl)pyrimidin-2-amine;N-[(1S,2R)-2-(3,3-difluoropropyl)cyclopentyl]-4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-5-(trifluoromethyl)pyrimidin-2-amine;4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-N-[(1S,2S)-2-(3-fluoroazetidin-1-yl)cyclopentyl]-5-(trifluoromethyl)pyrimidin-2-amine;4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-N-[(1S,2R)-2-(3-fluoroazetidin-1-yl)cyclopentyl]-5-(trifluoromethyl)pyrimidin-2-amine;4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-N-[(1S,2R)-2-(3-fluoropropyl)cyclopentyl]-5-(trifluoromethyl)pyrimidin-2-amine;4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-N-[(1S,2S)-2-[(3S)-3-fluoropyrrolidin-1-yl]cyclopentyl]-5-(trifluoromethyl)pyrimidin-2-amine;4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-N-[(1S,2S)-2-[(3R)-3-fluoropyrrolidin-1-yl]cyclopentyl]-5-(trifluoromethyl)pyrimidin-2-amine;4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-N-[(1S,2S)-2-(3-methoxypyrrolidin-1-yl)cyclopentyl]-5-(trifluoromethyl)pyrimidin-2-amine;4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-N-[(1S,2S)-2-pyrrolidin-1-ylcyclobutyl]-5-(trifluoromethyl)pyrimidin-2-amine;2-[[(1S,2S)-2-[[4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-5-(trifluoromethyl)pyrimidin-2-yl]amino]cyclopentyl]amino]ethanol;trans-(1S,2S)-1-N-[4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-5-(trifluoromethyl)pyrimidin-2-yl]-2-N-ethylcyclopentane-1,2-diamine;trans-(1S,2S)-1-N-[4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-5-(trifluoromethyl)pyrimidin-2-yl]-2-N-(2-methoxyethyl)cyclopentane-1,2-diamine?
N-[(1S,2S)-2-(azetidin-1-yl)cyclopentyl]-4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-5-(trifluoromethyl)pyrimidin-2-amine;N-[(1S,2R)-2-(3,3-difluoropropyl)cyclopentyl]-4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-5-(trifluoromethyl)pyrimidin-2-amine;4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-N-[(1S,2S)-2-(3-fluoroazetidin-1-yl)cyclopentyl]-5-(trifluoromethyl)pyrimidin-2-amine;4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-N-[(1S,2R)-2-(3-fluoroazetidin-1-yl)cyclopentyl]-5-(trifluoromethyl)pyrimidin-2-amine;4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-N-[(1S,2R)-2-(3-fluoropropyl)cyclopentyl]-5-(trifluoromethyl)pyrimidin-2-amine;4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-N-[(1S,2S)-2-[(3S)-3-fluoropyrrolidin-1-yl]cyclopentyl]-5-(trifluoromethyl)pyrimidin-2-amine;4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-N-[(1S,2S)-2-[(3R)-3-fluoropyrrolidin-1-yl]cyclopentyl]-5-(trifluoromethyl)pyrimidin-2-amine;4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-N-[(1S,2S)-2-(3-methoxypyrrolidin-1-yl)cyclopentyl]-5-(trifluoromethyl)pyrimidin-2-amine;4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-N-[(1S,2S)-2-pyrrolidin-1-ylcyclobutyl]-5-(trifluoromethyl)pyrimidin-2-amine;2-[[(1S,2S)-2-[[4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-5-(trifluoromethyl)pyrimidin-2-yl]amino]cyclopentyl]amino]ethanol;trans-(1S,2S)-1-N-[4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-5-(trifluoromethyl)pyrimidin-2-yl]-2-N-ethylcyclopentane-1,2-diamine;trans-(1S,2S)-1-N-[4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-5-(trifluoromethyl)pyrimidin-2-yl]-2-N-(2-methoxyethyl)cyclopentane-1,2-diamine has a molecular weight of 6140.48 g/mol, XLogP of 64.04, 71 rotatable bonds, 16 hydrogen bond donors, and 85 hydrogen bond acceptors.
Where does this data come from?
All data for N-[(1S,2S)-2-(azetidin-1-yl)cyclopentyl]-4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-5-(trifluoromethyl)pyrimidin-2-amine;N-[(1S,2R)-2-(3,3-difluoropropyl)cyclopentyl]-4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-5-(trifluoromethyl)pyrimidin-2-amine;4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-N-[(1S,2S)-2-(3-fluoroazetidin-1-yl)cyclopentyl]-5-(trifluoromethyl)pyrimidin-2-amine;4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-N-[(1S,2R)-2-(3-fluoroazetidin-1-yl)cyclopentyl]-5-(trifluoromethyl)pyrimidin-2-amine;4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-N-[(1S,2R)-2-(3-fluoropropyl)cyclopentyl]-5-(trifluoromethyl)pyrimidin-2-amine;4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-N-[(1S,2S)-2-[(3S)-3-fluoropyrrolidin-1-yl]cyclopentyl]-5-(trifluoromethyl)pyrimidin-2-amine;4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-N-[(1S,2S)-2-[(3R)-3-fluoropyrrolidin-1-yl]cyclopentyl]-5-(trifluoromethyl)pyrimidin-2-amine;4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-N-[(1S,2S)-2-(3-methoxypyrrolidin-1-yl)cyclopentyl]-5-(trifluoromethyl)pyrimidin-2-amine;4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-N-[(1S,2S)-2-pyrrolidin-1-ylcyclobutyl]-5-(trifluoromethyl)pyrimidin-2-amine;2-[[(1S,2S)-2-[[4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-5-(trifluoromethyl)pyrimidin-2-yl]amino]cyclopentyl]amino]ethanol;trans-(1S,2S)-1-N-[4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-5-(trifluoromethyl)pyrimidin-2-yl]-2-N-ethylcyclopentane-1,2-diamine;trans-(1S,2S)-1-N-[4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-7H-cyclopenta[b]pyridin-5-yl]-5-(trifluoromethyl)pyrimidin-2-yl]-2-N-(2-methoxyethyl)cyclopentane-1,2-diamine is sourced from PubChem (CID 163779613), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).