5-[[2-(1H-benzimidazol-2-yl)-3,4-dihydro-1H-isoquinolin-7-yl]oxy]-3,4-dihydro-1H-1,8-naphthyridin-2-one;2-(1H-benzimidazol-2-yl)-7-phenylmethoxy-3,4-dihydro-1H-isoquinoline;2-chloro-1H-benzimidazole;5-fluoro-3,4-dihydro-1H-1,8-naphthyridin-2-one;methane;7-phenylmethoxy-1,2,3,4-tetrahydroisoquinoline;trimethyl-[2-[[2-(7-phenylmethoxy-3,4-dihydro-1H-isoquinolin-2-yl)benzimidazol-1-yl]methoxy]ethyl]silane;2-[1-(2-trimethylsilylethoxymethyl)benzimidazol-2-yl]-3,4-dihydro-1H-isoquinolin-7-ol;5-[[2-[1-(2-trimethylsilylethoxymethyl)benzimidazol-2-yl]-3,4-dihydro-1H-isoquinolin-7-yl]oxy]-3,4-dihydro-1H-1,8-naphthyridin-2-one

C160H174ClFN24O12Si3 — CID 163839342

About 5-[[2-(1H-benzimidazol-2-yl)-3,4-dihydro-1H-isoquinolin-7-yl]oxy]-3,4-dihydro-1H-1,8-naphthyridin-2-one;2-(1H-benzimidazol-2-yl)-7-phenylmethoxy-3,4-dihydro-1H-isoquinoline;2-chloro-1H-benzimidazole;5-fluoro-3,4-dihydro-1H-1,8-naphthyridin-2-one;methane;7-phenylmethoxy-1,2,3,4-tetrahydroisoquinoline;trimethyl-[2-[[2-(7-phenylmethoxy-3,4-dihydro-1H-isoquinolin-2-yl)benzimidazol-1-yl]methoxy]ethyl]silane;2-[1-(2-trimethylsilylethoxymethyl)benzimidazol-2-yl]-3,4-dihydro-1H-isoquinolin-7-ol;5-[[2-[1-(2-trimethylsilylethoxymethyl)benzimidazol-2-yl]-3,4-dihydro-1H-isoquinolin-7-yl]oxy]-3,4-dihydro-1H-1,8-naphthyridin-2-one

5-[[2-(1H-benzimidazol-2-yl)-3,4-dihydro-1H-isoquinolin-7-yl]oxy]-3,4-dihydro-1H-1,8-naphthyridin-2-one;2-(1H-benzimidazol-2-yl)-7-phenylmethoxy-3,4-dihydro-1H-isoquinoline;2-chloro-1H-benzimidazole;5-fluoro-3,4-dihydro-1H-1,8-naphthyridin-2-one;methane;7-phenylmethoxy-1,2,3,4-tetrahydroisoquinoline;trimethyl-[2-[[2-(7-phenylmethoxy-3,4-dihydro-1H-isoquinolin-2-yl)benzimidazol-1-yl]methoxy]ethyl]silane;2-[1-(2-trimethylsilylethoxymethyl)benzimidazol-2-yl]-3,4-dihydro-1H-isoquinolin-7-ol;5-[[2-[1-(2-trimethylsilylethoxymethyl)benzimidazol-2-yl]-3,4-dihydro-1H-isoquinolin-7-yl]oxy]-3,4-dihydro-1H-1,8-naphthyridin-2-one (PubChem CID 163839342) has the molecular formula C160H174ClFN24O12Si3 and a molecular weight of 2764.02 g/mol. Its IUPAC name is 5-[[2-(1H-benzimidazol-2-yl)-3,4-dihydro-1H-isoquinolin-7-yl]oxy]-3,4-dihydro-1H-1,8-naphthyridin-2-one;2-(1H-benzimidazol-2-yl)-7-phenylmethoxy-3,4-dihydro-1H-isoquinoline;2-chloro-1H-benzimidazole;5-fluoro-3,4-dihydro-1H-1,8-naphthyridin-2-one;methane;7-phenylmethoxy-1,2,3,4-tetrahydroisoquinoline;trimethyl-[2-[[2-(7-phenylmethoxy-3,4-dihydro-1H-isoquinolin-2-yl)benzimidazol-1-yl]methoxy]ethyl]silane;2-[1-(2-trimethylsilylethoxymethyl)benzimidazol-2-yl]-3,4-dihydro-1H-isoquinolin-7-ol;5-[[2-[1-(2-trimethylsilylethoxymethyl)benzimidazol-2-yl]-3,4-dihydro-1H-isoquinolin-7-yl]oxy]-3,4-dihydro-1H-1,8-naphthyridin-2-one.

Molecular Properties

• Compound Name: 5-[[2-(1H-benzimidazol-2-yl)-3,4-dihydro-1H-isoquinolin-7-yl]oxy]-3,4-dihydro-1H-1,8-naphthyridin-2-one;2-(1H-benzimidazol-2-yl)-7-phenylmethoxy-3,4-dihydro-1H-isoquinoline;2-chloro-1H-benzimidazole;5-fluoro-3,4-dihydro-1H-1,8-naphthyridin-2-one;methane;7-phenylmethoxy-1,2,3,4-tetrahydroisoquinoline;trimethyl-[2-[[2-(7-phenylmethoxy-3,4-dihydro-1H-isoquinolin-2-yl)benzimidazol-1-yl]methoxy]ethyl]silane;2-[1-(2-trimethylsilylethoxymethyl)benzimidazol-2-yl]-3,4-dihydro-1H-isoquinolin-7-ol;5-[[2-[1-(2-trimethylsilylethoxymethyl)benzimidazol-2-yl]-3,4-dihydro-1H-isoquinolin-7-yl]oxy]-3,4-dihydro-1H-1,8-naphthyridin-2-one
• PubChem CID: 163839342
• Molecular Formula: C160H174ClFN24O12Si3
• Molecular Weight: 2764.02 g/mol
• Exact Mass: 2761.27
• IUPAC Name: 5-[[2-(1H-benzimidazol-2-yl)-3,4-dihydro-1H-isoquinolin-7-yl]oxy]-3,4-dihydro-1H-1,8-naphthyridin-2-one;2-(1H-benzimidazol-2-yl)-7-phenylmethoxy-3,4-dihydro-1H-isoquinoline;2-chloro-1H-benzimidazole;5-fluoro-3,4-dihydro-1H-1,8-naphthyridin-2-one;methane;7-phenylmethoxy-1,2,3,4-tetrahydroisoquinoline;trimethyl-[2-[[2-(7-phenylmethoxy-3,4-dihydro-1H-isoquinolin-2-yl)benzimidazol-1-yl]methoxy]ethyl]silane;2-[1-(2-trimethylsilylethoxymethyl)benzimidazol-2-yl]-3,4-dihydro-1H-isoquinolin-7-ol;5-[[2-[1-(2-trimethylsilylethoxymethyl)benzimidazol-2-yl]-3,4-dihydro-1H-isoquinolin-7-yl]oxy]-3,4-dihydro-1H-1,8-naphthyridin-2-one
• SMILES: C.C[Si](C)(C)CCOCn1c(N2CCc3ccc(O)cc3C2)nc2ccccc21.C[Si](C)(C)CCOCn1c(N2CCc3ccc(OCc4ccccc4)cc3C2)nc2ccccc21.C[Si](C)(C)CCOCn1c(N2CCc3ccc(Oc4ccnc5c4CCC(=O)N5)cc3C2)nc2ccccc21.Clc1nc2ccccc2[nH]1.O=C1CCc2c(F)ccnc2N1.O=C1CCc2c(Oc3ccc4c(c3)CN(c3nc5ccccc5[nH]3)CC4)ccnc2N1.c1ccc(COc2ccc3c(c2)CN(c2nc4ccccc4[nH]2)CC3)cc1.c1ccc(COc2ccc3c(c2)CNCC3)cc1
• InChI: InChI=1S/C30H35N5O3Si.C29H35N3O2Si.C24H21N5O2.C23H21N3O.C22H29N3O2Si.C16H17NO.C8H7FN2O.C7H5ClN2.CH4/c1-39(2,3)17-16-37-20-35-26-7-5-4-6-25(26)32-30(35)34-15-13-21-8-9-23(18-22(21)19-34)38-27-12-14-31-29-24(27)10-11-28(36)33-29;1-35(2,3)18-17-33-22-32-28-12-8-7-11-27(28)30-29(32)31-16-15-24-13-14-26(19-25(24)20-31)34-21-23-9-5-4-6-10-23;30-22-8-7-18-21(9-11-25-23(18)28-22)31-17-6-5-15-10-12-29(14-16(15)13-17)24-26-19-3-1-2-4-20(19)27-24;1-2-6-17(7-3-1)16-27-20-11-10-18-12-13-26(15-19(18)14-20)23-24-21-8-4-5-9-22(21)25-23;1-28(2,3)13-12-27-16-25-21-7-5-4-6-20(21)23-22(25)24-11-10-17-8-9-19(26)14-18(17)15-24;1-2-4-13(5-3-1)12-18-16-7-6-14-8-9-17-11-15(14)10-16;9-6-3-4-10-8-5(6)1-2-7(12)11-8;8-7-9-5-3-1-2-4-6(5)10-7;/h4-9,12,14,18H,10-11,13,15-17,19-20H2,1-3H3,(H,31,33,36);4-14,19H,15-18,20-22H2,1-3H3;1-6,9,11,13H,7-8,10,12,14H2,(H,26,27)(H,25,28,30);1-11,14H,12-13,15-16H2,(H,24,25);4-9,14,26H,10-13,15-16H2,1-3H3;1-7,10,17H,8-9,11-12H2;3-4H,1-2H2,(H,10,11,12);1-4H,(H,9,10);1H4
• InChIKey: OKNVURUSLCDUJW-UHFFFAOYSA-N
• XLogP: 32.86
• TPSA: 387.77 Ų
• H-Bond Donors: 8
• H-Bond Acceptors: 30
• Rotatable Bonds: 33
• Heavy Atoms: 201
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2764.02
LogP ≤ 5	32.86
H-Bond Donors ≤ 5	8
H-Bond Acceptors ≤ 10	30

Computed Properties (RDKit)

• Structural Alerts: {'alert_name': 'Aliphatic_long_chain', 'substructure': 'N/A'}, {'alert_name': 'heavy_metal', 'substructure': 'N/A'}

Frequently Asked Questions

What is the IUPAC name of 5-[[2-(1H-benzimidazol-2-yl)-3,4-dihydro-1H-isoquinolin-7-yl]oxy]-3,4-dihydro-1H-1,8-naphthyridin-2-one;2-(1H-benzimidazol-2-yl)-7-phenylmethoxy-3,4-dihydro-1H-isoquinoline;2-chloro-1H-benzimidazole;5-fluoro-3,4-dihydro-1H-1,8-naphthyridin-2-one;methane;7-phenylmethoxy-1,2,3,4-tetrahydroisoquinoline;trimethyl-[2-[[2-(7-phenylmethoxy-3,4-dihydro-1H-isoquinolin-2-yl)benzimidazol-1-yl]methoxy]ethyl]silane;2-[1-(2-trimethylsilylethoxymethyl)benzimidazol-2-yl]-3,4-dihydro-1H-isoquinolin-7-ol;5-[[2-[1-(2-trimethylsilylethoxymethyl)benzimidazol-2-yl]-3,4-dihydro-1H-isoquinolin-7-yl]oxy]-3,4-dihydro-1H-1,8-naphthyridin-2-one?

The IUPAC name of 5-[[2-(1H-benzimidazol-2-yl)-3,4-dihydro-1H-isoquinolin-7-yl]oxy]-3,4-dihydro-1H-1,8-naphthyridin-2-one;2-(1H-benzimidazol-2-yl)-7-phenylmethoxy-3,4-dihydro-1H-isoquinoline;2-chloro-1H-benzimidazole;5-fluoro-3,4-dihydro-1H-1,8-naphthyridin-2-one;methane;7-phenylmethoxy-1,2,3,4-tetrahydroisoquinoline;trimethyl-[2-[[2-(7-phenylmethoxy-3,4-dihydro-1H-isoquinolin-2-yl)benzimidazol-1-yl]methoxy]ethyl]silane;2-[1-(2-trimethylsilylethoxymethyl)benzimidazol-2-yl]-3,4-dihydro-1H-isoquinolin-7-ol;5-[[2-[1-(2-trimethylsilylethoxymethyl)benzimidazol-2-yl]-3,4-dihydro-1H-isoquinolin-7-yl]oxy]-3,4-dihydro-1H-1,8-naphthyridin-2-one (CID 163839342) is 5-[[2-(1H-benzimidazol-2-yl)-3,4-dihydro-1H-isoquinolin-7-yl]oxy]-3,4-dihydro-1H-1,8-naphthyridin-2-one;2-(1H-benzimidazol-2-yl)-7-phenylmethoxy-3,4-dihydro-1H-isoquinoline;2-chloro-1H-benzimidazole;5-fluoro-3,4-dihydro-1H-1,8-naphthyridin-2-one;methane;7-phenylmethoxy-1,2,3,4-tetrahydroisoquinoline;trimethyl-[2-[[2-(7-phenylmethoxy-3,4-dihydro-1H-isoquinolin-2-yl)benzimidazol-1-yl]methoxy]ethyl]silane;2-[1-(2-trimethylsilylethoxymethyl)benzimidazol-2-yl]-3,4-dihydro-1H-isoquinolin-7-ol;5-[[2-[1-(2-trimethylsilylethoxymethyl)benzimidazol-2-yl]-3,4-dihydro-1H-isoquinolin-7-yl]oxy]-3,4-dihydro-1H-1,8-naphthyridin-2-one.

What is the SMILES notation for 5-[[2-(1H-benzimidazol-2-yl)-3,4-dihydro-1H-isoquinolin-7-yl]oxy]-3,4-dihydro-1H-1,8-naphthyridin-2-one;2-(1H-benzimidazol-2-yl)-7-phenylmethoxy-3,4-dihydro-1H-isoquinoline;2-chloro-1H-benzimidazole;5-fluoro-3,4-dihydro-1H-1,8-naphthyridin-2-one;methane;7-phenylmethoxy-1,2,3,4-tetrahydroisoquinoline;trimethyl-[2-[[2-(7-phenylmethoxy-3,4-dihydro-1H-isoquinolin-2-yl)benzimidazol-1-yl]methoxy]ethyl]silane;2-[1-(2-trimethylsilylethoxymethyl)benzimidazol-2-yl]-3,4-dihydro-1H-isoquinolin-7-ol;5-[[2-[1-(2-trimethylsilylethoxymethyl)benzimidazol-2-yl]-3,4-dihydro-1H-isoquinolin-7-yl]oxy]-3,4-dihydro-1H-1,8-naphthyridin-2-one?

The canonical SMILES for 5-[[2-(1H-benzimidazol-2-yl)-3,4-dihydro-1H-isoquinolin-7-yl]oxy]-3,4-dihydro-1H-1,8-naphthyridin-2-one;2-(1H-benzimidazol-2-yl)-7-phenylmethoxy-3,4-dihydro-1H-isoquinoline;2-chloro-1H-benzimidazole;5-fluoro-3,4-dihydro-1H-1,8-naphthyridin-2-one;methane;7-phenylmethoxy-1,2,3,4-tetrahydroisoquinoline;trimethyl-[2-[[2-(7-phenylmethoxy-3,4-dihydro-1H-isoquinolin-2-yl)benzimidazol-1-yl]methoxy]ethyl]silane;2-[1-(2-trimethylsilylethoxymethyl)benzimidazol-2-yl]-3,4-dihydro-1H-isoquinolin-7-ol;5-[[2-[1-(2-trimethylsilylethoxymethyl)benzimidazol-2-yl]-3,4-dihydro-1H-isoquinolin-7-yl]oxy]-3,4-dihydro-1H-1,8-naphthyridin-2-one is C.C[Si](C)(C)CCOCn1c(N2CCc3ccc(O)cc3C2)nc2ccccc21.C[Si](C)(C)CCOCn1c(N2CCc3ccc(OCc4ccccc4)cc3C2)nc2ccccc21.C[Si](C)(C)CCOCn1c(N2CCc3ccc(Oc4ccnc5c4CCC(=O)N5)cc3C2)nc2ccccc21.Clc1nc2ccccc2[nH]1.O=C1CCc2c(F)ccnc2N1.O=C1CCc2c(Oc3ccc4c(c3)CN(c3nc5ccccc5[nH]3)CC4)ccnc2N1.c1ccc(COc2ccc3c(c2)CN(c2nc4ccccc4[nH]2)CC3)cc1.c1ccc(COc2ccc3c(c2)CNCC3)cc1.

What is the InChIKey of 5-[[2-(1H-benzimidazol-2-yl)-3,4-dihydro-1H-isoquinolin-7-yl]oxy]-3,4-dihydro-1H-1,8-naphthyridin-2-one;2-(1H-benzimidazol-2-yl)-7-phenylmethoxy-3,4-dihydro-1H-isoquinoline;2-chloro-1H-benzimidazole;5-fluoro-3,4-dihydro-1H-1,8-naphthyridin-2-one;methane;7-phenylmethoxy-1,2,3,4-tetrahydroisoquinoline;trimethyl-[2-[[2-(7-phenylmethoxy-3,4-dihydro-1H-isoquinolin-2-yl)benzimidazol-1-yl]methoxy]ethyl]silane;2-[1-(2-trimethylsilylethoxymethyl)benzimidazol-2-yl]-3,4-dihydro-1H-isoquinolin-7-ol;5-[[2-[1-(2-trimethylsilylethoxymethyl)benzimidazol-2-yl]-3,4-dihydro-1H-isoquinolin-7-yl]oxy]-3,4-dihydro-1H-1,8-naphthyridin-2-one?

The InChIKey is OKNVURUSLCDUJW-UHFFFAOYSA-N. The full InChI is InChI=1S/C30H35N5O3Si.C29H35N3O2Si.C24H21N5O2.C23H21N3O.C22H29N3O2Si.C16H17NO.C8H7FN2O.C7H5ClN2.CH4/c1-39(2,3)17-16-37-20-35-26-7-5-4-6-25(26)32-30(35)34-15-13-21-8-9-23(18-22(21)19-34)38-27-12-14-31-29-24(27)10-11-28(36)33-29;1-35(2,3)18-17-33-22-32-28-12-8-7-11-27(28)30-29(32)31-16-15-24-13-14-26(19-25(24)20-31)34-21-23-9-5-4-6-10-23;30-22-8-7-18-21(9-11-25-23(18)28-22)31-17-6-5-15-10-12-29(14-16(15)13-17)24-26-19-3-1-2-4-20(19)27-24;1-2-6-17(7-3-1)16-27-20-11-10-18-12-13-26(15-19(18)14-20)23-24-21-8-4-5-9-22(21)25-23;1-28(2,3)13-12-27-16-25-21-7-5-4-6-20(21)23-22(25)24-11-10-17-8-9-19(26)14-18(17)15-24;1-2-4-13(5-3-1)12-18-16-7-6-14-8-9-17-11-15(14)10-16;9-6-3-4-10-8-5(6)1-2-7(12)11-8;8-7-9-5-3-1-2-4-6(5)10-7;/h4-9,12,14,18H,10-11,13,15-17,19-20H2,1-3H3,(H,31,33,36);4-14,19H,15-18,20-22H2,1-3H3;1-6,9,11,13H,7-8,10,12,14H2,(H,26,27)(H,25,28,30);1-11,14H,12-13,15-16H2,(H,24,25);4-9,14,26H,10-13,15-16H2,1-3H3;1-7,10,17H,8-9,11-12H2;3-4H,1-2H2,(H,10,11,12);1-4H,(H,9,10);1H4.

What are the key properties of 5-[[2-(1H-benzimidazol-2-yl)-3,4-dihydro-1H-isoquinolin-7-yl]oxy]-3,4-dihydro-1H-1,8-naphthyridin-2-one;2-(1H-benzimidazol-2-yl)-7-phenylmethoxy-3,4-dihydro-1H-isoquinoline;2-chloro-1H-benzimidazole;5-fluoro-3,4-dihydro-1H-1,8-naphthyridin-2-one;methane;7-phenylmethoxy-1,2,3,4-tetrahydroisoquinoline;trimethyl-[2-[[2-(7-phenylmethoxy-3,4-dihydro-1H-isoquinolin-2-yl)benzimidazol-1-yl]methoxy]ethyl]silane;2-[1-(2-trimethylsilylethoxymethyl)benzimidazol-2-yl]-3,4-dihydro-1H-isoquinolin-7-ol;5-[[2-[1-(2-trimethylsilylethoxymethyl)benzimidazol-2-yl]-3,4-dihydro-1H-isoquinolin-7-yl]oxy]-3,4-dihydro-1H-1,8-naphthyridin-2-one?

5-[[2-(1H-benzimidazol-2-yl)-3,4-dihydro-1H-isoquinolin-7-yl]oxy]-3,4-dihydro-1H-1,8-naphthyridin-2-one;2-(1H-benzimidazol-2-yl)-7-phenylmethoxy-3,4-dihydro-1H-isoquinoline;2-chloro-1H-benzimidazole;5-fluoro-3,4-dihydro-1H-1,8-naphthyridin-2-one;methane;7-phenylmethoxy-1,2,3,4-tetrahydroisoquinoline;trimethyl-[2-[[2-(7-phenylmethoxy-3,4-dihydro-1H-isoquinolin-2-yl)benzimidazol-1-yl]methoxy]ethyl]silane;2-[1-(2-trimethylsilylethoxymethyl)benzimidazol-2-yl]-3,4-dihydro-1H-isoquinolin-7-ol;5-[[2-[1-(2-trimethylsilylethoxymethyl)benzimidazol-2-yl]-3,4-dihydro-1H-isoquinolin-7-yl]oxy]-3,4-dihydro-1H-1,8-naphthyridin-2-one has a molecular weight of 2764.02 g/mol, XLogP of 32.86, 33 rotatable bonds, 8 hydrogen bond donors, and 30 hydrogen bond acceptors.

Where does this data come from?

All data for 5-[[2-(1H-benzimidazol-2-yl)-3,4-dihydro-1H-isoquinolin-7-yl]oxy]-3,4-dihydro-1H-1,8-naphthyridin-2-one;2-(1H-benzimidazol-2-yl)-7-phenylmethoxy-3,4-dihydro-1H-isoquinoline;2-chloro-1H-benzimidazole;5-fluoro-3,4-dihydro-1H-1,8-naphthyridin-2-one;methane;7-phenylmethoxy-1,2,3,4-tetrahydroisoquinoline;trimethyl-[2-[[2-(7-phenylmethoxy-3,4-dihydro-1H-isoquinolin-2-yl)benzimidazol-1-yl]methoxy]ethyl]silane;2-[1-(2-trimethylsilylethoxymethyl)benzimidazol-2-yl]-3,4-dihydro-1H-isoquinolin-7-ol;5-[[2-[1-(2-trimethylsilylethoxymethyl)benzimidazol-2-yl]-3,4-dihydro-1H-isoquinolin-7-yl]oxy]-3,4-dihydro-1H-1,8-naphthyridin-2-one is sourced from PubChem (CID 163839342), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).