2-amino-8-[(2,5-difluorophenyl)methoxy]-N-[(1R)-2-hydroxy-1-phenylethyl]imidazo[1,2-a]pyridine-3-carboxamide

C23H20F2N4O3 — CID 163848577

IUPAC2-amino-8-[(2,5-difluorophenyl)methoxy]-N-[(1R)-2-hydroxy-1-phenylethyl]imidazo[1,2-a]pyridine-3-carboxamide
SMILESNc1nc2c(OCc3cc(F)ccc3F)cccn2c1C(=O)N[C@@H](CO)c1ccccc1
InChIInChI=1S/C23H20F2N4O3/c24-16-8-9-17(25)15(11-16)13-32-19-7-4-10-29-20(21(26)28-22(19)29)23(31)27-18(12-30)14-5-2-1-3-6-14/h1-11,18,30H,12-13,26H2,(H,27,31)/t18-/m0/s1
InChIKeyOSIKHXZXCNTYOS-SFHVURJKSA-N
MW438.43 g/mol
LogP3.24
Rot. Bonds7

About 2-amino-8-[(2,5-difluorophenyl)methoxy]-N-[(1R)-2-hydroxy-1-phenylethyl]imidazo[1,2-a]pyridine-3-carboxamide

2-amino-8-[(2,5-difluorophenyl)methoxy]-N-[(1R)-2-hydroxy-1-phenylethyl]imidazo[1,2-a]pyridine-3-carboxamide (PubChem CID 163848577) has the molecular formula C23H20F2N4O3 and a molecular weight of 438.43 g/mol. Its IUPAC name is 2-amino-8-[(2,5-difluorophenyl)methoxy]-N-[(1R)-2-hydroxy-1-phenylethyl]imidazo[1,2-a]pyridine-3-carboxamide.

Molecular Properties

Compound Name2-amino-8-[(2,5-difluorophenyl)methoxy]-N-[(1R)-2-hydroxy-1-phenylethyl]imidazo[1,2-a]pyridine-3-carboxamide
PubChem CID163848577
Molecular FormulaC23H20F2N4O3
Molecular Weight438.43 g/mol
Exact Mass438.15
IUPAC Name2-amino-8-[(2,5-difluorophenyl)methoxy]-N-[(1R)-2-hydroxy-1-phenylethyl]imidazo[1,2-a]pyridine-3-carboxamide
SMILESNc1nc2c(OCc3cc(F)ccc3F)cccn2c1C(=O)N[C@@H](CO)c1ccccc1
InChIInChI=1S/C23H20F2N4O3/c24-16-8-9-17(25)15(11-16)13-32-19-7-4-10-29-20(21(26)28-22(19)29)23(31)27-18(12-30)14-5-2-1-3-6-14/h1-11,18,30H,12-13,26H2,(H,27,31)/t18-/m0/s1
InChIKeyOSIKHXZXCNTYOS-SFHVURJKSA-N
XLogP3.24
TPSA101.88 Ų
H-Bond Donors3
H-Bond Acceptors6
Rotatable Bonds7
Heavy Atoms32
Complexity—

Lipinski Rule of Five

Passes Rule of Five

RuleValue
MW ≤ 500438.43
LogP ≤ 53.24
H-Bond Donors ≤ 53
H-Bond Acceptors ≤ 106

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Related Compounds

8-[(2,6-difluorophenyl)methoxy]-N-[(1R)-1-(3-fluorophenyl)-2-hydroxyethyl]-2-methylimidazo[1,2-a]pyridine-3-carboxamide
CID 90090866
8-[(2-fluoro-6-methylphenyl)methoxy]-N-[(1R)-2-hydroxy-1-phenylethyl]-2-methylimidazo[1,2-a]pyridine-3-carboxamide
CID 90090393
N-[(1R)-1-(4-fluorophenyl)-2-hydroxyethyl]-2-methyl-8-[(2,3,6-trifluorophenyl)methoxy]imidazo[1,2-a]pyridine-3-carboxamide
CID 90090948
8-(3,3-dimethylbutoxy)-N-[(1R)-2-hydroxy-1-phenylethyl]-2-methylimidazo[1,2-a]pyridine-3-carboxamide
CID 154474836
8-[(2,6-difluorophenyl)methoxy]-N-[(1S,2S)-1,3-dihydroxy-1-phenylpropan-2-yl]-2-methylimidazo[1,2-a]pyridine-3-carboxamide
CID 90091301
[2-(3,4-difluorophenyl)-2-[(2-methyl-8-phenylmethoxyimidazo[1,2-a]pyridine-3-carbonyl)amino]ethyl]carbamic acid
CID 90114108
N-[(1R)-2-hydroxy-1-phenylethyl]-2-methyl-8-(spiro[3.5]nonan-7-ylmethoxy)imidazo[1,2-a]pyridine-3-carboxamide
CID 90090874
8-[(2,6-difluorophenyl)methoxy]-N-[(1R)-2-hydroxy-1-(2-phenyltetrazol-5-yl)ethyl]-2-methylimidazo[1,2-a]pyridine-3-carboxamide
CID 163742259
4-fluoro-N-[(1S)-2-hydroxy-1-phenylethyl]-3-methoxybenzamide
CID 103945331
8-[(2-chlorophenyl)methoxy]-N-(1,3-dihydroxypropan-2-yl)-2-methylimidazo[1,2-a]pyridine-3-carboxamide
CID 90115835
N-[(1R)-2-[tert-butyl(dimethyl)silyl]oxy-1-phenylethyl]-2-methyl-8-phenylmethoxyimidazo[1,2-a]pyridine-3-carboxamide
CID 86713410
[2-[[8-[(2-chloro-6-fluorophenyl)methoxy]-2-methylimidazo[1,2-a]pyridine-3-carbonyl]amino]-2-(3,4-difluorophenyl)ethyl]carbamic acid
CID 90114317

Frequently Asked Questions

What is the IUPAC name of 2-amino-8-[(2,5-difluorophenyl)methoxy]-N-[(1R)-2-hydroxy-1-phenylethyl]imidazo[1,2-a]pyridine-3-carboxamide?
The IUPAC name of 2-amino-8-[(2,5-difluorophenyl)methoxy]-N-[(1R)-2-hydroxy-1-phenylethyl]imidazo[1,2-a]pyridine-3-carboxamide (CID 163848577) is 2-amino-8-[(2,5-difluorophenyl)methoxy]-N-[(1R)-2-hydroxy-1-phenylethyl]imidazo[1,2-a]pyridine-3-carboxamide.
What is the SMILES notation for 2-amino-8-[(2,5-difluorophenyl)methoxy]-N-[(1R)-2-hydroxy-1-phenylethyl]imidazo[1,2-a]pyridine-3-carboxamide?
The canonical SMILES for 2-amino-8-[(2,5-difluorophenyl)methoxy]-N-[(1R)-2-hydroxy-1-phenylethyl]imidazo[1,2-a]pyridine-3-carboxamide is Nc1nc2c(OCc3cc(F)ccc3F)cccn2c1C(=O)N[C@@H](CO)c1ccccc1.
What is the InChIKey of 2-amino-8-[(2,5-difluorophenyl)methoxy]-N-[(1R)-2-hydroxy-1-phenylethyl]imidazo[1,2-a]pyridine-3-carboxamide?
The InChIKey is OSIKHXZXCNTYOS-SFHVURJKSA-N. The full InChI is InChI=1S/C23H20F2N4O3/c24-16-8-9-17(25)15(11-16)13-32-19-7-4-10-29-20(21(26)28-22(19)29)23(31)27-18(12-30)14-5-2-1-3-6-14/h1-11,18,30H,12-13,26H2,(H,27,31)/t18-/m0/s1.
What are the key properties of 2-amino-8-[(2,5-difluorophenyl)methoxy]-N-[(1R)-2-hydroxy-1-phenylethyl]imidazo[1,2-a]pyridine-3-carboxamide?
2-amino-8-[(2,5-difluorophenyl)methoxy]-N-[(1R)-2-hydroxy-1-phenylethyl]imidazo[1,2-a]pyridine-3-carboxamide has a molecular weight of 438.43 g/mol, XLogP of 3.24, 7 rotatable bonds, 3 hydrogen bond donors, and 6 hydrogen bond acceptors.
Where does this data come from?
All data for 2-amino-8-[(2,5-difluorophenyl)methoxy]-N-[(1R)-2-hydroxy-1-phenylethyl]imidazo[1,2-a]pyridine-3-carboxamide is sourced from PubChem (CID 163848577), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).