1-[3-(2-fluoro-4-pyridinyl)-1H-pyrazol-5-yl]-3-[4-(4-morpholin-4-yl-7H-pyrrolo[2,3-d]pyrimidin-6-yl)phenyl]propan-2-one;1-[3-[6-(2-hydroxypropan-2-yl)-3-pyridinyl]-1H-pyrazol-5-yl]-3-[4-(5-morpholin-4-ylimidazo[1,2-a]pyridin-2-yl)phenyl]propan-2-one;1-[3-(2-methyl-4-pyridinyl)-1H-pyrazol-5-yl]-3-[4-(4-morpholin-4-yl-7H-pyrrolo[2,3-d]pyrimidin-6-yl)phenyl]propan-2-one;1-[4-(5-morpholin-4-ylimidazo[1,2-a]pyridin-2-yl)phenyl]-3-(3-pyridin-3-yl-1H-pyrazol-5-yl)propan-2-one;1-[4-(4-morpholin-4-yl-1H-imidazo[4,5-c]pyridin-2-yl)phenyl]-3-(3-pyridin-3-yl-1H-pyrazol-5-yl)propan-2-one;1-[4-(4-morpholin-4-yl-7H-pyrrolo[2,3-d]pyrimidin-6-yl)phenyl]-3-(3-pyridin-4-yl-1H-pyrazol-5-yl)propan-2-one;1-[4-(5-morpholin-4-yl-[1,2,4]triazolo[1,5-c]pyrimidin-2-yl)phenyl]-3-(3-pyridin-3-yl-1H-pyrazol-5-yl)propan-2-one

C194H183FN48O15 — CID 163906028

IUPAC1-[3-(2-fluoro-4-pyridinyl)-1H-pyrazol-5-yl]-3-[4-(4-morpholin-4-yl-7H-pyrrolo[2,3-d]pyrimidin-6-yl)phenyl]propan-2-one;1-[3-[6-(2-hydroxypropan-2-yl)-3-pyridinyl]-1H-pyrazol-5-yl]-3-[4-(5-morpholin-4-ylimidazo[1,2-a]pyridin-2-yl)phenyl]propan-2-one;1-[3-(2-methyl-4-pyridinyl)-1H-pyrazol-5-yl]-3-[4-(4-morpholin-4-yl-7H-pyrrolo[2,3-d]pyrimidin-6-yl)phenyl]propan-2-one;1-[4-(5-morpholin-4-ylimidazo[1,2-a]pyridin-2-yl)phenyl]-3-(3-pyridin-3-yl-1H-pyrazol-5-yl)propan-2-one;1-[4-(4-morpholin-4-yl-1H-imidazo[4,5-c]pyridin-2-yl)phenyl]-3-(3-pyridin-3-yl-1H-pyrazol-5-yl)propan-2-one;1-[4-(4-morpholin-4-yl-7H-pyrrolo[2,3-d]pyrimidin-6-yl)phenyl]-3-(3-pyridin-4-yl-1H-pyrazol-5-yl)propan-2-one;1-[4-(5-morpholin-4-yl-[1,2,4]triazolo[1,5-c]pyrimidin-2-yl)phenyl]-3-(3-pyridin-3-yl-1H-pyrazol-5-yl)propan-2-one
SMILESCC(C)(O)c1ccc(-c2cc(CC(=O)Cc3ccc(-c4cn5c(N6CCOCC6)cccc5n4)cc3)[nH]n2)cn1.Cc1cc(-c2cc(CC(=O)Cc3ccc(-c4cc5c(N6CCOCC6)ncnc5[nH]4)cc3)[nH]n2)ccn1.O=C(Cc1ccc(-c2cc3c(N4CCOCC4)ncnc3[nH]2)cc1)Cc1cc(-c2ccnc(F)c2)n[nH]1.O=C(Cc1ccc(-c2cc3c(N4CCOCC4)ncnc3[nH]2)cc1)Cc1cc(-c2ccncc2)n[nH]1.O=C(Cc1ccc(-c2cn3c(N4CCOCC4)cccc3n2)cc1)Cc1cc(-c2cccnc2)n[nH]1.O=C(Cc1ccc(-c2nc3c(N4CCOCC4)nccc3[nH]2)cc1)Cc1cc(-c2cccnc2)n[nH]1.O=C(Cc1ccc(-c2nc3ccnc(N4CCOCC4)n3n2)cc1)Cc1cc(-c2cccnc2)n[nH]1
InChIInChI=1S/C31H32N6O3.C28H27N7O2.C28H26N6O2.C27H24FN7O2.2C27H25N7O2.C26H24N8O2/c1-31(2,39)28-11-10-23(19-32-28)26-18-24(34-35-26)17-25(38)16-21-6-8-22(9-7-21)27-20-37-29(33-27)4-3-5-30(37)36-12-14-40-15-13-36;1-18-12-21(6-7-29-18)26-15-22(33-34-26)14-23(36)13-19-2-4-20(5-3-19)25-16-24-27(32-25)30-17-31-28(24)35-8-10-37-11-9-35;35-24(16-23-17-25(32-31-23)22-3-2-10-29-18-22)15-20-6-8-21(9-7-20)26-19-34-27(30-26)4-1-5-28(34)33-11-13-36-14-12-33;28-25-12-19(5-6-29-25)24-14-20(33-34-24)13-21(36)11-17-1-3-18(4-2-17)23-15-22-26(32-23)30-16-31-27(22)35-7-9-37-10-8-35;35-22(14-21-15-25(33-32-21)20-5-7-28-8-6-20)13-18-1-3-19(4-2-18)24-16-23-26(31-24)29-17-30-27(23)34-9-11-36-12-10-34;35-22(15-21-16-24(33-32-21)20-2-1-8-28-17-20)14-18-3-5-19(6-4-18)26-30-23-7-9-29-27(25(23)31-26)34-10-12-36-13-11-34;35-22(15-21-16-23(31-30-21)20-2-1-8-27-17-20)14-18-3-5-19(6-4-18)25-29-24-7-9-28-26(34(24)32-25)33-10-12-36-13-11-33/h3-11,18-20,39H,12-17H2,1-2H3,(H,34,35);2-7,12,15-17H,8-11,13-14H2,1H3,(H,33,34)(H,30,31,32);1-10,17-19H,11-16H2,(H,31,32);1-6,12,14-16H,7-11,13H2,(H,33,34)(H,30,31,32);1-8,15-17H,9-14H2,(H,32,33)(H,29,30,31);1-9,16-17H,10-15H2,(H,30,31)(H,32,33);1-9,16-17H,10-15H2,(H,30,31)
InChIKeyQNZJLZFCUKFTSU-UHFFFAOYSA-N
MW3445.92 g/mol
LogP25.80
Rot. Bonds50

About 1-[3-(2-fluoro-4-pyridinyl)-1H-pyrazol-5-yl]-3-[4-(4-morpholin-4-yl-7H-pyrrolo[2,3-d]pyrimidin-6-yl)phenyl]propan-2-one;1-[3-[6-(2-hydroxypropan-2-yl)-3-pyridinyl]-1H-pyrazol-5-yl]-3-[4-(5-morpholin-4-ylimidazo[1,2-a]pyridin-2-yl)phenyl]propan-2-one;1-[3-(2-methyl-4-pyridinyl)-1H-pyrazol-5-yl]-3-[4-(4-morpholin-4-yl-7H-pyrrolo[2,3-d]pyrimidin-6-yl)phenyl]propan-2-one;1-[4-(5-morpholin-4-ylimidazo[1,2-a]pyridin-2-yl)phenyl]-3-(3-pyridin-3-yl-1H-pyrazol-5-yl)propan-2-one;1-[4-(4-morpholin-4-yl-1H-imidazo[4,5-c]pyridin-2-yl)phenyl]-3-(3-pyridin-3-yl-1H-pyrazol-5-yl)propan-2-one;1-[4-(4-morpholin-4-yl-7H-pyrrolo[2,3-d]pyrimidin-6-yl)phenyl]-3-(3-pyridin-4-yl-1H-pyrazol-5-yl)propan-2-one;1-[4-(5-morpholin-4-yl-[1,2,4]triazolo[1,5-c]pyrimidin-2-yl)phenyl]-3-(3-pyridin-3-yl-1H-pyrazol-5-yl)propan-2-one

1-[3-(2-fluoro-4-pyridinyl)-1H-pyrazol-5-yl]-3-[4-(4-morpholin-4-yl-7H-pyrrolo[2,3-d]pyrimidin-6-yl)phenyl]propan-2-one;1-[3-[6-(2-hydroxypropan-2-yl)-3-pyridinyl]-1H-pyrazol-5-yl]-3-[4-(5-morpholin-4-ylimidazo[1,2-a]pyridin-2-yl)phenyl]propan-2-one;1-[3-(2-methyl-4-pyridinyl)-1H-pyrazol-5-yl]-3-[4-(4-morpholin-4-yl-7H-pyrrolo[2,3-d]pyrimidin-6-yl)phenyl]propan-2-one;1-[4-(5-morpholin-4-ylimidazo[1,2-a]pyridin-2-yl)phenyl]-3-(3-pyridin-3-yl-1H-pyrazol-5-yl)propan-2-one;1-[4-(4-morpholin-4-yl-1H-imidazo[4,5-c]pyridin-2-yl)phenyl]-3-(3-pyridin-3-yl-1H-pyrazol-5-yl)propan-2-one;1-[4-(4-morpholin-4-yl-7H-pyrrolo[2,3-d]pyrimidin-6-yl)phenyl]-3-(3-pyridin-4-yl-1H-pyrazol-5-yl)propan-2-one;1-[4-(5-morpholin-4-yl-[1,2,4]triazolo[1,5-c]pyrimidin-2-yl)phenyl]-3-(3-pyridin-3-yl-1H-pyrazol-5-yl)propan-2-one (PubChem CID 163906028) has the molecular formula C194H183FN48O15 and a molecular weight of 3445.92 g/mol. Its IUPAC name is 1-[3-(2-fluoro-4-pyridinyl)-1H-pyrazol-5-yl]-3-[4-(4-morpholin-4-yl-7H-pyrrolo[2,3-d]pyrimidin-6-yl)phenyl]propan-2-one;1-[3-[6-(2-hydroxypropan-2-yl)-3-pyridinyl]-1H-pyrazol-5-yl]-3-[4-(5-morpholin-4-ylimidazo[1,2-a]pyridin-2-yl)phenyl]propan-2-one;1-[3-(2-methyl-4-pyridinyl)-1H-pyrazol-5-yl]-3-[4-(4-morpholin-4-yl-7H-pyrrolo[2,3-d]pyrimidin-6-yl)phenyl]propan-2-one;1-[4-(5-morpholin-4-ylimidazo[1,2-a]pyridin-2-yl)phenyl]-3-(3-pyridin-3-yl-1H-pyrazol-5-yl)propan-2-one;1-[4-(4-morpholin-4-yl-1H-imidazo[4,5-c]pyridin-2-yl)phenyl]-3-(3-pyridin-3-yl-1H-pyrazol-5-yl)propan-2-one;1-[4-(4-morpholin-4-yl-7H-pyrrolo[2,3-d]pyrimidin-6-yl)phenyl]-3-(3-pyridin-4-yl-1H-pyrazol-5-yl)propan-2-one;1-[4-(5-morpholin-4-yl-[1,2,4]triazolo[1,5-c]pyrimidin-2-yl)phenyl]-3-(3-pyridin-3-yl-1H-pyrazol-5-yl)propan-2-one.

Molecular Properties

Compound Name1-[3-(2-fluoro-4-pyridinyl)-1H-pyrazol-5-yl]-3-[4-(4-morpholin-4-yl-7H-pyrrolo[2,3-d]pyrimidin-6-yl)phenyl]propan-2-one;1-[3-[6-(2-hydroxypropan-2-yl)-3-pyridinyl]-1H-pyrazol-5-yl]-3-[4-(5-morpholin-4-ylimidazo[1,2-a]pyridin-2-yl)phenyl]propan-2-one;1-[3-(2-methyl-4-pyridinyl)-1H-pyrazol-5-yl]-3-[4-(4-morpholin-4-yl-7H-pyrrolo[2,3-d]pyrimidin-6-yl)phenyl]propan-2-one;1-[4-(5-morpholin-4-ylimidazo[1,2-a]pyridin-2-yl)phenyl]-3-(3-pyridin-3-yl-1H-pyrazol-5-yl)propan-2-one;1-[4-(4-morpholin-4-yl-1H-imidazo[4,5-c]pyridin-2-yl)phenyl]-3-(3-pyridin-3-yl-1H-pyrazol-5-yl)propan-2-one;1-[4-(4-morpholin-4-yl-7H-pyrrolo[2,3-d]pyrimidin-6-yl)phenyl]-3-(3-pyridin-4-yl-1H-pyrazol-5-yl)propan-2-one;1-[4-(5-morpholin-4-yl-[1,2,4]triazolo[1,5-c]pyrimidin-2-yl)phenyl]-3-(3-pyridin-3-yl-1H-pyrazol-5-yl)propan-2-one
PubChem CID163906028
Molecular FormulaC194H183FN48O15
Molecular Weight3445.92 g/mol
Exact Mass3443.50
IUPAC Name1-[3-(2-fluoro-4-pyridinyl)-1H-pyrazol-5-yl]-3-[4-(4-morpholin-4-yl-7H-pyrrolo[2,3-d]pyrimidin-6-yl)phenyl]propan-2-one;1-[3-[6-(2-hydroxypropan-2-yl)-3-pyridinyl]-1H-pyrazol-5-yl]-3-[4-(5-morpholin-4-ylimidazo[1,2-a]pyridin-2-yl)phenyl]propan-2-one;1-[3-(2-methyl-4-pyridinyl)-1H-pyrazol-5-yl]-3-[4-(4-morpholin-4-yl-7H-pyrrolo[2,3-d]pyrimidin-6-yl)phenyl]propan-2-one;1-[4-(5-morpholin-4-ylimidazo[1,2-a]pyridin-2-yl)phenyl]-3-(3-pyridin-3-yl-1H-pyrazol-5-yl)propan-2-one;1-[4-(4-morpholin-4-yl-1H-imidazo[4,5-c]pyridin-2-yl)phenyl]-3-(3-pyridin-3-yl-1H-pyrazol-5-yl)propan-2-one;1-[4-(4-morpholin-4-yl-7H-pyrrolo[2,3-d]pyrimidin-6-yl)phenyl]-3-(3-pyridin-4-yl-1H-pyrazol-5-yl)propan-2-one;1-[4-(5-morpholin-4-yl-[1,2,4]triazolo[1,5-c]pyrimidin-2-yl)phenyl]-3-(3-pyridin-3-yl-1H-pyrazol-5-yl)propan-2-one
SMILESCC(C)(O)c1ccc(-c2cc(CC(=O)Cc3ccc(-c4cn5c(N6CCOCC6)cccc5n4)cc3)[nH]n2)cn1.Cc1cc(-c2cc(CC(=O)Cc3ccc(-c4cc5c(N6CCOCC6)ncnc5[nH]4)cc3)[nH]n2)ccn1.O=C(Cc1ccc(-c2cc3c(N4CCOCC4)ncnc3[nH]2)cc1)Cc1cc(-c2ccnc(F)c2)n[nH]1.O=C(Cc1ccc(-c2cc3c(N4CCOCC4)ncnc3[nH]2)cc1)Cc1cc(-c2ccncc2)n[nH]1.O=C(Cc1ccc(-c2cn3c(N4CCOCC4)cccc3n2)cc1)Cc1cc(-c2cccnc2)n[nH]1.O=C(Cc1ccc(-c2nc3c(N4CCOCC4)nccc3[nH]2)cc1)Cc1cc(-c2cccnc2)n[nH]1.O=C(Cc1ccc(-c2nc3ccnc(N4CCOCC4)n3n2)cc1)Cc1cc(-c2cccnc2)n[nH]1
InChIInChI=1S/C31H32N6O3.C28H27N7O2.C28H26N6O2.C27H24FN7O2.2C27H25N7O2.C26H24N8O2/c1-31(2,39)28-11-10-23(19-32-28)26-18-24(34-35-26)17-25(38)16-21-6-8-22(9-7-21)27-20-37-29(33-27)4-3-5-30(37)36-12-14-40-15-13-36;1-18-12-21(6-7-29-18)26-15-22(33-34-26)14-23(36)13-19-2-4-20(5-3-19)25-16-24-27(32-25)30-17-31-28(24)35-8-10-37-11-9-35;35-24(16-23-17-25(32-31-23)22-3-2-10-29-18-22)15-20-6-8-21(9-7-20)26-19-34-27(30-26)4-1-5-28(34)33-11-13-36-14-12-33;28-25-12-19(5-6-29-25)24-14-20(33-34-24)13-21(36)11-17-1-3-18(4-2-17)23-15-22-26(32-23)30-16-31-27(22)35-7-9-37-10-8-35;35-22(14-21-15-25(33-32-21)20-5-7-28-8-6-20)13-18-1-3-19(4-2-18)24-16-23-26(31-24)29-17-30-27(23)34-9-11-36-12-10-34;35-22(15-21-16-24(33-32-21)20-2-1-8-28-17-20)14-18-3-5-19(6-4-18)26-30-23-7-9-29-27(25(23)31-26)34-10-12-36-13-11-34;35-22(15-21-16-23(31-30-21)20-2-1-8-27-17-20)14-18-3-5-19(6-4-18)25-29-24-7-9-28-26(34(24)32-25)33-10-12-36-13-11-33/h3-11,18-20,39H,12-17H2,1-2H3,(H,34,35);2-7,12,15-17H,8-11,13-14H2,1H3,(H,33,34)(H,30,31,32);1-10,17-19H,11-16H2,(H,31,32);1-6,12,14-16H,7-11,13H2,(H,33,34)(H,30,31,32);1-8,15-17H,9-14H2,(H,32,33)(H,29,30,31);1-9,16-17H,10-15H2,(H,30,31)(H,32,33);1-9,16-17H,10-15H2,(H,30,31)
InChIKeyQNZJLZFCUKFTSU-UHFFFAOYSA-N
XLogP25.80
TPSA761.96 Ų
H-Bond Donors12
H-Bond Acceptors52
Rotatable Bonds50
Heavy Atoms258
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5003445.92
LogP ≤ 525.80
H-Bond Donors ≤ 512
H-Bond Acceptors ≤ 1052

Computed Properties (RDKit)

Structural Alerts{'alert_name': '2-halo_pyridine', 'substructure': 'N/A'}

Analyze 1-[3-(2-fluoro-4-pyridinyl)-1H-pyrazol-5-yl]-3-[4-(4-morpholin-4-yl-7H-pyrrolo[2,3-d]pyrimidin-6-yl)phenyl]propan-2-one;1-[3-[6-(2-hydroxypropan-2-yl)-3-pyridinyl]-1H-pyrazol-5-yl]-3-[4-(5-morpholin-4-ylimidazo[1,2-a]pyridin-2-yl)phenyl]propan-2-one;1-[3-(2-methyl-4-pyridinyl)-1H-pyrazol-5-yl]-3-[4-(4-morpholin-4-yl-7H-pyrrolo[2,3-d]pyrimidin-6-yl)phenyl]propan-2-one;1-[4-(5-morpholin-4-ylimidazo[1,2-a]pyridin-2-yl)phenyl]-3-(3-pyridin-3-yl-1H-pyrazol-5-yl)propan-2-one;1-[4-(4-morpholin-4-yl-1H-imidazo[4,5-c]pyridin-2-yl)phenyl]-3-(3-pyridin-3-yl-1H-pyrazol-5-yl)propan-2-one;1-[4-(4-morpholin-4-yl-7H-pyrrolo[2,3-d]pyrimidin-6-yl)phenyl]-3-(3-pyridin-4-yl-1H-pyrazol-5-yl)propan-2-one;1-[4-(5-morpholin-4-yl-[1,2,4]triazolo[1,5-c]pyrimidin-2-yl)phenyl]-3-(3-pyridin-3-yl-1H-pyrazol-5-yl)propan-2-one with MolForge

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Launch Full Analysis

Related Compounds

1-[4-[4-(dimethylamino)piperidine-1-carbonyl]phenyl]-3-[4-(7-methyl-4-morpholin-4-ylpyrrolo[2,1-f][1,2,4]triazin-2-yl)phenyl]urea;2-fluoro-N-methyl-4-[[4-(4-morpholin-4-ylpyrrolo[2,1-f][1,2,4]triazin-2-yl)phenyl]carbamoylamino]benzamide;1-[4-[7-(2-hydroxypropan-2-yl)-4-morpholin-4-ylpyrrolo[2,1-f][1,2,4]triazin-2-yl]phenyl]-3-pyridin-3-ylurea;1-[4-(7-methyl-4-morpholin-4-ylpyrrolo[2,1-f][1,2,4]triazin-2-yl)phenyl]-3-[4-(4-methylpiperazine-1-carbonyl)phenyl]urea;1-[4-[4-morpholin-4-yl-7-(trifluoromethyl)pyrrolo[2,1-f][1,2,4]triazin-2-yl]phenyl]-3-pyridin-3-ylurea
CID 159695567
1-[4-[4-(4-methylimidazol-1-yl)-1H-imidazo[4,5-c]pyridin-2-yl]phenyl]-3-(1-methyl-3-phenylpyrazol-5-yl)propan-2-one;1-[4-[4-(4-methylimidazol-1-yl)-1H-imidazo[4,5-c]pyridin-2-yl]phenyl]-3-(3-phenyl-1H-pyrazol-5-yl)propan-2-one;1-[4-[6-(4-methylimidazol-1-yl)-7H-purin-8-yl]phenyl]-3-(1-methyl-3-phenylpyrazol-5-yl)propan-2-one;1-[4-[6-(4-methylimidazol-1-yl)-7H-purin-8-yl]phenyl]-3-(3-phenyl-1H-pyrazol-5-yl)propan-2-one;1-[4-[4-(4-methylimidazol-1-yl)-1H-pyrrolo[3,2-c]pyridin-2-yl]phenyl]-3-(3-phenyl-1H-pyrazol-5-yl)propan-2-one;1-[4-[4-(4-methylimidazol-1-yl)-7H-pyrrolo[2,3-d]pyrimidin-6-yl]phenyl]-3-(1-methyl-3-phenylpyrazol-5-yl)propan-2-one;1-[4-[4-(4-methylimidazol-1-yl)-7H-pyrrolo[2,3-d]pyrimidin-6-yl]phenyl]-3-(3-phenyl-1H-pyrazol-5-yl)propan-2-one
CID 157271294
1-(1-methyl-3-pyridin-3-ylpyrazol-5-yl)-3-[4-(4-morpholin-4-yl-1H-imidazo[4,5-c]pyridin-2-yl)phenyl]propan-2-one;1-(1-methyl-3-pyridin-3-ylpyrazol-5-yl)-3-[4-(6-morpholin-4-yl-7H-purin-8-yl)phenyl]propan-2-one;1-(1-methyl-3-pyridin-3-ylpyrazol-5-yl)-3-[4-(4-morpholin-4-yl-7H-pyrrolo[2,3-d]pyrimidin-6-yl)phenyl]propan-2-one;1-[4-(4-morpholin-4-yl-1H-imidazo[4,5-c]pyridin-2-yl)phenyl]-3-(3-pyridin-3-yl-1H-pyrazol-5-yl)propan-2-one;1-[4-(6-morpholin-4-yl-7H-purin-8-yl)phenyl]-3-(3-pyridin-3-yl-1H-pyrazol-5-yl)propan-2-one;1-[4-(4-morpholin-4-yl-1H-pyrrolo[3,2-c]pyridin-2-yl)phenyl]-3-(3-pyridin-3-yl-1H-pyrazol-5-yl)propan-2-one;1-[4-(4-morpholin-4-yl-7H-pyrrolo[2,3-d]pyrimidin-6-yl)phenyl]-3-(3-pyridin-3-yl-1H-pyrazol-5-yl)propan-2-one
CID 157375485
3-methyl-N-[5-[3-(7-pyridin-2-yl-3H-imidazo[4,5-c]pyridin-2-yl)-2H-pyrazolo[3,4-b]pyridin-5-yl]-3-pyridinyl]butanamide;2-methyl-N-[5-[3-(7-pyridin-2-yl-3H-imidazo[4,5-c]pyridin-2-yl)-2H-pyrazolo[3,4-b]pyridin-5-yl]-3-pyridinyl]propanamide;1-[5-[3-(7-pyridin-2-yl-3H-imidazo[4,5-c]pyridin-2-yl)-2H-pyrazolo[3,4-b]pyridin-5-yl]-2-pyridinyl]butan-2-one;N-[5-[3-(7-pyridin-2-yl-3H-imidazo[4,5-c]pyridin-2-yl)-2H-pyrazolo[3,4-b]pyridin-5-yl]-3-pyridinyl]cyclopropanecarboxamide;N-[5-[3-(7-pyridin-2-yl-3H-imidazo[4,5-c]pyridin-2-yl)-2H-pyrazolo[3,4-b]pyridin-5-yl]-3-pyridinyl]morpholine-4-carboxamide
CID 157400785
1-[5-[3-[7-(4-fluorophenyl)-3H-imidazo[4,5-c]pyridin-2-yl]-2H-pyrazolo[3,4-b]pyridin-5-yl]-2-pyridinyl]butan-2-one;N-[5-[3-[7-(4-fluorophenyl)-3H-imidazo[4,5-c]pyridin-2-yl]-2H-pyrazolo[3,4-b]pyridin-5-yl]-3-pyridinyl]cyclopropanecarboxamide;N-[5-[3-[7-(4-fluorophenyl)-3H-imidazo[4,5-c]pyridin-2-yl]-2H-pyrazolo[3,4-b]pyridin-5-yl]-3-pyridinyl]-3-methylbutanamide;N-[5-[3-[7-(4-fluorophenyl)-3H-imidazo[4,5-c]pyridin-2-yl]-2H-pyrazolo[3,4-b]pyridin-5-yl]-3-pyridinyl]-2-methylpropanamide;N-[5-[3-[7-(4-fluorophenyl)-3H-imidazo[4,5-c]pyridin-2-yl]-2H-pyrazolo[3,4-b]pyridin-5-yl]-3-pyridinyl]morpholine-4-carboxamide
CID 157469981
1-(1-methyl-3-phenylpyrazol-5-yl)-3-[4-(6-morpholin-4-yl-7H-purin-8-yl)phenyl]propan-2-one;1-(1-methyl-3-phenylpyrazol-5-yl)-3-[4-(4-morpholin-4-yl-1H-pyrrolo[3,2-c]pyridin-2-yl)phenyl]propan-2-one;1-(1-methyl-3-phenylpyrazol-5-yl)-3-[4-(4-morpholin-4-yl-7H-pyrrolo[2,3-d]pyrimidin-6-yl)phenyl]propan-2-one;1-(1-methyl-3-pyridin-4-ylpyrazol-5-yl)-3-[4-(4-morpholin-4-yl-1H-imidazo[4,5-c]pyridin-2-yl)phenyl]propan-2-one
CID 157523253
1-(1-methyl-3-pyridin-3-ylpyrazol-5-yl)-3-[4-(4-morpholin-4-yl-1H-imidazo[4,5-c]pyridin-2-yl)phenyl]propan-2-one;1-(1-methyl-3-pyridin-3-ylpyrazol-5-yl)-3-[4-(6-morpholin-4-yl-7H-purin-8-yl)phenyl]propan-2-one;1-(1-methyl-3-pyridin-3-ylpyrazol-5-yl)-3-[4-(4-morpholin-4-yl-1H-pyrrolo[3,2-c]pyridin-2-yl)phenyl]propan-2-one;1-(1-methyl-3-pyridin-3-ylpyrazol-5-yl)-3-[4-(4-morpholin-4-yl-7H-pyrrolo[2,3-d]pyrimidin-6-yl)phenyl]propan-2-one
CID 157532189
1-[5-[3-[7-(3-fluorophenyl)-3H-imidazo[4,5-c]pyridin-2-yl]-2H-pyrazolo[3,4-b]pyridin-5-yl]-2-pyridinyl]butan-2-one;1-[5-[3-[7-(4-fluorophenyl)-3H-imidazo[4,5-c]pyridin-2-yl]-2H-pyrazolo[3,4-b]pyridin-5-yl]-2-pyridinyl]butan-2-one;N-[5-[3-[7-(4-fluorophenyl)-3H-imidazo[4,5-c]pyridin-2-yl]-2H-pyrazolo[3,4-b]pyridin-5-yl]-3-pyridinyl]-3-methylbutanamide;N-[5-[3-[7-(3-fluorophenyl)-3H-imidazo[4,5-c]pyridin-2-yl]-2H-pyrazolo[3,4-b]pyridin-5-yl]-3-pyridinyl]-2-methylpropanamide;N-[5-[3-[7-(4-fluorophenyl)-3H-imidazo[4,5-c]pyridin-2-yl]-2H-pyrazolo[3,4-b]pyridin-5-yl]-3-pyridinyl]-2-methylpropanamide
CID 157564552
1-(1-methyl-3-pyridin-3-ylpyrazol-5-yl)-3-[4-(4-morpholin-4-yl-1H-imidazo[4,5-c]pyridin-2-yl)phenyl]propan-2-one;1-(1-methyl-3-pyridin-3-ylpyrazol-5-yl)-3-[4-(4-morpholin-4-yl-1H-pyrrolo[3,2-c]pyridin-2-yl)phenyl]propan-2-one
CID 157755694
1-[5-[3-[4-(3-fluorophenyl)-1H-benzimidazol-2-yl]-2H-pyrazolo[3,4-b]pyridin-5-yl]-2-pyridinyl]butan-2-one;N-[5-[3-[4-(4-fluorophenyl)-1H-benzimidazol-2-yl]-2H-pyrazolo[3,4-b]pyridin-5-yl]-3-pyridinyl]cyclopropanecarboxamide;3-[5-[3-[4-(4-fluorophenyl)-1H-benzimidazol-2-yl]-2H-pyrazolo[3,4-b]pyridin-5-yl]-3-pyridinyl]-1,1-dimethylurea;N-[5-[3-[4-(4-fluorophenyl)-1H-benzimidazol-2-yl]-2H-pyrazolo[3,4-b]pyridin-5-yl]-3-pyridinyl]-4-methylpiperazine-1-carboxamide;N-[5-[3-[4-(4-fluorophenyl)-1H-benzimidazol-2-yl]-2H-pyrazolo[3,4-b]pyridin-5-yl]-3-pyridinyl]morpholine-4-carboxamide
CID 157794963
4-[4-amino-5-(1H-indol-2-yl)imidazo[5,1-f][1,2,4]triazin-7-yl]cyclohexane-1-carboxylic acid;1-[4-[4-amino-5-(7-methyl-1H-indol-2-yl)imidazo[5,1-f][1,2,4]triazin-7-yl]cyclohexyl]-2-phenylethanone;benzyl 3-[4-[4-amino-5-(1H-indol-2-yl)imidazo[5,1-f][1,2,4]triazin-7-yl]cyclohexyl]propanoate;methane;methyl 4-[4-amino-5-(7-methyl-1H-indol-2-yl)imidazo[5,1-f][1,2,4]triazin-7-yl]cyclohexane-1-carboxylate
CID 157968573
4-[10-(4-Fluorophenyl)-11-(oxan-4-yl)-2,4,5,10-tetrazatricyclo[7.3.0.03,7]dodeca-1(9),2,5,7,11-pentaen-12-yl]benzamide;4-[10-(4-fluorophenyl)-11-(oxan-4-yl)-2,4,5,10-tetrazatricyclo[7.3.0.03,7]dodeca-1(9),2,5,7,11-pentaen-12-yl]benzoic acid;4-[10-(4-fluorophenyl)-11-propan-2-yl-2,4,5,8,10-pentazatricyclo[7.3.0.03,7]dodeca-1,3(7),5,8,11-pentaen-12-yl]benzoic acid
CID 157997517

Frequently Asked Questions

What is the IUPAC name of 1-[3-(2-fluoro-4-pyridinyl)-1H-pyrazol-5-yl]-3-[4-(4-morpholin-4-yl-7H-pyrrolo[2,3-d]pyrimidin-6-yl)phenyl]propan-2-one;1-[3-[6-(2-hydroxypropan-2-yl)-3-pyridinyl]-1H-pyrazol-5-yl]-3-[4-(5-morpholin-4-ylimidazo[1,2-a]pyridin-2-yl)phenyl]propan-2-one;1-[3-(2-methyl-4-pyridinyl)-1H-pyrazol-5-yl]-3-[4-(4-morpholin-4-yl-7H-pyrrolo[2,3-d]pyrimidin-6-yl)phenyl]propan-2-one;1-[4-(5-morpholin-4-ylimidazo[1,2-a]pyridin-2-yl)phenyl]-3-(3-pyridin-3-yl-1H-pyrazol-5-yl)propan-2-one;1-[4-(4-morpholin-4-yl-1H-imidazo[4,5-c]pyridin-2-yl)phenyl]-3-(3-pyridin-3-yl-1H-pyrazol-5-yl)propan-2-one;1-[4-(4-morpholin-4-yl-7H-pyrrolo[2,3-d]pyrimidin-6-yl)phenyl]-3-(3-pyridin-4-yl-1H-pyrazol-5-yl)propan-2-one;1-[4-(5-morpholin-4-yl-[1,2,4]triazolo[1,5-c]pyrimidin-2-yl)phenyl]-3-(3-pyridin-3-yl-1H-pyrazol-5-yl)propan-2-one?
The IUPAC name of 1-[3-(2-fluoro-4-pyridinyl)-1H-pyrazol-5-yl]-3-[4-(4-morpholin-4-yl-7H-pyrrolo[2,3-d]pyrimidin-6-yl)phenyl]propan-2-one;1-[3-[6-(2-hydroxypropan-2-yl)-3-pyridinyl]-1H-pyrazol-5-yl]-3-[4-(5-morpholin-4-ylimidazo[1,2-a]pyridin-2-yl)phenyl]propan-2-one;1-[3-(2-methyl-4-pyridinyl)-1H-pyrazol-5-yl]-3-[4-(4-morpholin-4-yl-7H-pyrrolo[2,3-d]pyrimidin-6-yl)phenyl]propan-2-one;1-[4-(5-morpholin-4-ylimidazo[1,2-a]pyridin-2-yl)phenyl]-3-(3-pyridin-3-yl-1H-pyrazol-5-yl)propan-2-one;1-[4-(4-morpholin-4-yl-1H-imidazo[4,5-c]pyridin-2-yl)phenyl]-3-(3-pyridin-3-yl-1H-pyrazol-5-yl)propan-2-one;1-[4-(4-morpholin-4-yl-7H-pyrrolo[2,3-d]pyrimidin-6-yl)phenyl]-3-(3-pyridin-4-yl-1H-pyrazol-5-yl)propan-2-one;1-[4-(5-morpholin-4-yl-[1,2,4]triazolo[1,5-c]pyrimidin-2-yl)phenyl]-3-(3-pyridin-3-yl-1H-pyrazol-5-yl)propan-2-one (CID 163906028) is 1-[3-(2-fluoro-4-pyridinyl)-1H-pyrazol-5-yl]-3-[4-(4-morpholin-4-yl-7H-pyrrolo[2,3-d]pyrimidin-6-yl)phenyl]propan-2-one;1-[3-[6-(2-hydroxypropan-2-yl)-3-pyridinyl]-1H-pyrazol-5-yl]-3-[4-(5-morpholin-4-ylimidazo[1,2-a]pyridin-2-yl)phenyl]propan-2-one;1-[3-(2-methyl-4-pyridinyl)-1H-pyrazol-5-yl]-3-[4-(4-morpholin-4-yl-7H-pyrrolo[2,3-d]pyrimidin-6-yl)phenyl]propan-2-one;1-[4-(5-morpholin-4-ylimidazo[1,2-a]pyridin-2-yl)phenyl]-3-(3-pyridin-3-yl-1H-pyrazol-5-yl)propan-2-one;1-[4-(4-morpholin-4-yl-1H-imidazo[4,5-c]pyridin-2-yl)phenyl]-3-(3-pyridin-3-yl-1H-pyrazol-5-yl)propan-2-one;1-[4-(4-morpholin-4-yl-7H-pyrrolo[2,3-d]pyrimidin-6-yl)phenyl]-3-(3-pyridin-4-yl-1H-pyrazol-5-yl)propan-2-one;1-[4-(5-morpholin-4-yl-[1,2,4]triazolo[1,5-c]pyrimidin-2-yl)phenyl]-3-(3-pyridin-3-yl-1H-pyrazol-5-yl)propan-2-one.
What is the SMILES notation for 1-[3-(2-fluoro-4-pyridinyl)-1H-pyrazol-5-yl]-3-[4-(4-morpholin-4-yl-7H-pyrrolo[2,3-d]pyrimidin-6-yl)phenyl]propan-2-one;1-[3-[6-(2-hydroxypropan-2-yl)-3-pyridinyl]-1H-pyrazol-5-yl]-3-[4-(5-morpholin-4-ylimidazo[1,2-a]pyridin-2-yl)phenyl]propan-2-one;1-[3-(2-methyl-4-pyridinyl)-1H-pyrazol-5-yl]-3-[4-(4-morpholin-4-yl-7H-pyrrolo[2,3-d]pyrimidin-6-yl)phenyl]propan-2-one;1-[4-(5-morpholin-4-ylimidazo[1,2-a]pyridin-2-yl)phenyl]-3-(3-pyridin-3-yl-1H-pyrazol-5-yl)propan-2-one;1-[4-(4-morpholin-4-yl-1H-imidazo[4,5-c]pyridin-2-yl)phenyl]-3-(3-pyridin-3-yl-1H-pyrazol-5-yl)propan-2-one;1-[4-(4-morpholin-4-yl-7H-pyrrolo[2,3-d]pyrimidin-6-yl)phenyl]-3-(3-pyridin-4-yl-1H-pyrazol-5-yl)propan-2-one;1-[4-(5-morpholin-4-yl-[1,2,4]triazolo[1,5-c]pyrimidin-2-yl)phenyl]-3-(3-pyridin-3-yl-1H-pyrazol-5-yl)propan-2-one?
The canonical SMILES for 1-[3-(2-fluoro-4-pyridinyl)-1H-pyrazol-5-yl]-3-[4-(4-morpholin-4-yl-7H-pyrrolo[2,3-d]pyrimidin-6-yl)phenyl]propan-2-one;1-[3-[6-(2-hydroxypropan-2-yl)-3-pyridinyl]-1H-pyrazol-5-yl]-3-[4-(5-morpholin-4-ylimidazo[1,2-a]pyridin-2-yl)phenyl]propan-2-one;1-[3-(2-methyl-4-pyridinyl)-1H-pyrazol-5-yl]-3-[4-(4-morpholin-4-yl-7H-pyrrolo[2,3-d]pyrimidin-6-yl)phenyl]propan-2-one;1-[4-(5-morpholin-4-ylimidazo[1,2-a]pyridin-2-yl)phenyl]-3-(3-pyridin-3-yl-1H-pyrazol-5-yl)propan-2-one;1-[4-(4-morpholin-4-yl-1H-imidazo[4,5-c]pyridin-2-yl)phenyl]-3-(3-pyridin-3-yl-1H-pyrazol-5-yl)propan-2-one;1-[4-(4-morpholin-4-yl-7H-pyrrolo[2,3-d]pyrimidin-6-yl)phenyl]-3-(3-pyridin-4-yl-1H-pyrazol-5-yl)propan-2-one;1-[4-(5-morpholin-4-yl-[1,2,4]triazolo[1,5-c]pyrimidin-2-yl)phenyl]-3-(3-pyridin-3-yl-1H-pyrazol-5-yl)propan-2-one is CC(C)(O)c1ccc(-c2cc(CC(=O)Cc3ccc(-c4cn5c(N6CCOCC6)cccc5n4)cc3)[nH]n2)cn1.Cc1cc(-c2cc(CC(=O)Cc3ccc(-c4cc5c(N6CCOCC6)ncnc5[nH]4)cc3)[nH]n2)ccn1.O=C(Cc1ccc(-c2cc3c(N4CCOCC4)ncnc3[nH]2)cc1)Cc1cc(-c2ccnc(F)c2)n[nH]1.O=C(Cc1ccc(-c2cc3c(N4CCOCC4)ncnc3[nH]2)cc1)Cc1cc(-c2ccncc2)n[nH]1.O=C(Cc1ccc(-c2cn3c(N4CCOCC4)cccc3n2)cc1)Cc1cc(-c2cccnc2)n[nH]1.O=C(Cc1ccc(-c2nc3c(N4CCOCC4)nccc3[nH]2)cc1)Cc1cc(-c2cccnc2)n[nH]1.O=C(Cc1ccc(-c2nc3ccnc(N4CCOCC4)n3n2)cc1)Cc1cc(-c2cccnc2)n[nH]1.
What is the InChIKey of 1-[3-(2-fluoro-4-pyridinyl)-1H-pyrazol-5-yl]-3-[4-(4-morpholin-4-yl-7H-pyrrolo[2,3-d]pyrimidin-6-yl)phenyl]propan-2-one;1-[3-[6-(2-hydroxypropan-2-yl)-3-pyridinyl]-1H-pyrazol-5-yl]-3-[4-(5-morpholin-4-ylimidazo[1,2-a]pyridin-2-yl)phenyl]propan-2-one;1-[3-(2-methyl-4-pyridinyl)-1H-pyrazol-5-yl]-3-[4-(4-morpholin-4-yl-7H-pyrrolo[2,3-d]pyrimidin-6-yl)phenyl]propan-2-one;1-[4-(5-morpholin-4-ylimidazo[1,2-a]pyridin-2-yl)phenyl]-3-(3-pyridin-3-yl-1H-pyrazol-5-yl)propan-2-one;1-[4-(4-morpholin-4-yl-1H-imidazo[4,5-c]pyridin-2-yl)phenyl]-3-(3-pyridin-3-yl-1H-pyrazol-5-yl)propan-2-one;1-[4-(4-morpholin-4-yl-7H-pyrrolo[2,3-d]pyrimidin-6-yl)phenyl]-3-(3-pyridin-4-yl-1H-pyrazol-5-yl)propan-2-one;1-[4-(5-morpholin-4-yl-[1,2,4]triazolo[1,5-c]pyrimidin-2-yl)phenyl]-3-(3-pyridin-3-yl-1H-pyrazol-5-yl)propan-2-one?
The InChIKey is QNZJLZFCUKFTSU-UHFFFAOYSA-N. The full InChI is InChI=1S/C31H32N6O3.C28H27N7O2.C28H26N6O2.C27H24FN7O2.2C27H25N7O2.C26H24N8O2/c1-31(2,39)28-11-10-23(19-32-28)26-18-24(34-35-26)17-25(38)16-21-6-8-22(9-7-21)27-20-37-29(33-27)4-3-5-30(37)36-12-14-40-15-13-36;1-18-12-21(6-7-29-18)26-15-22(33-34-26)14-23(36)13-19-2-4-20(5-3-19)25-16-24-27(32-25)30-17-31-28(24)35-8-10-37-11-9-35;35-24(16-23-17-25(32-31-23)22-3-2-10-29-18-22)15-20-6-8-21(9-7-20)26-19-34-27(30-26)4-1-5-28(34)33-11-13-36-14-12-33;28-25-12-19(5-6-29-25)24-14-20(33-34-24)13-21(36)11-17-1-3-18(4-2-17)23-15-22-26(32-23)30-16-31-27(22)35-7-9-37-10-8-35;35-22(14-21-15-25(33-32-21)20-5-7-28-8-6-20)13-18-1-3-19(4-2-18)24-16-23-26(31-24)29-17-30-27(23)34-9-11-36-12-10-34;35-22(15-21-16-24(33-32-21)20-2-1-8-28-17-20)14-18-3-5-19(6-4-18)26-30-23-7-9-29-27(25(23)31-26)34-10-12-36-13-11-34;35-22(15-21-16-23(31-30-21)20-2-1-8-27-17-20)14-18-3-5-19(6-4-18)25-29-24-7-9-28-26(34(24)32-25)33-10-12-36-13-11-33/h3-11,18-20,39H,12-17H2,1-2H3,(H,34,35);2-7,12,15-17H,8-11,13-14H2,1H3,(H,33,34)(H,30,31,32);1-10,17-19H,11-16H2,(H,31,32);1-6,12,14-16H,7-11,13H2,(H,33,34)(H,30,31,32);1-8,15-17H,9-14H2,(H,32,33)(H,29,30,31);1-9,16-17H,10-15H2,(H,30,31)(H,32,33);1-9,16-17H,10-15H2,(H,30,31).
What are the key properties of 1-[3-(2-fluoro-4-pyridinyl)-1H-pyrazol-5-yl]-3-[4-(4-morpholin-4-yl-7H-pyrrolo[2,3-d]pyrimidin-6-yl)phenyl]propan-2-one;1-[3-[6-(2-hydroxypropan-2-yl)-3-pyridinyl]-1H-pyrazol-5-yl]-3-[4-(5-morpholin-4-ylimidazo[1,2-a]pyridin-2-yl)phenyl]propan-2-one;1-[3-(2-methyl-4-pyridinyl)-1H-pyrazol-5-yl]-3-[4-(4-morpholin-4-yl-7H-pyrrolo[2,3-d]pyrimidin-6-yl)phenyl]propan-2-one;1-[4-(5-morpholin-4-ylimidazo[1,2-a]pyridin-2-yl)phenyl]-3-(3-pyridin-3-yl-1H-pyrazol-5-yl)propan-2-one;1-[4-(4-morpholin-4-yl-1H-imidazo[4,5-c]pyridin-2-yl)phenyl]-3-(3-pyridin-3-yl-1H-pyrazol-5-yl)propan-2-one;1-[4-(4-morpholin-4-yl-7H-pyrrolo[2,3-d]pyrimidin-6-yl)phenyl]-3-(3-pyridin-4-yl-1H-pyrazol-5-yl)propan-2-one;1-[4-(5-morpholin-4-yl-[1,2,4]triazolo[1,5-c]pyrimidin-2-yl)phenyl]-3-(3-pyridin-3-yl-1H-pyrazol-5-yl)propan-2-one?
1-[3-(2-fluoro-4-pyridinyl)-1H-pyrazol-5-yl]-3-[4-(4-morpholin-4-yl-7H-pyrrolo[2,3-d]pyrimidin-6-yl)phenyl]propan-2-one;1-[3-[6-(2-hydroxypropan-2-yl)-3-pyridinyl]-1H-pyrazol-5-yl]-3-[4-(5-morpholin-4-ylimidazo[1,2-a]pyridin-2-yl)phenyl]propan-2-one;1-[3-(2-methyl-4-pyridinyl)-1H-pyrazol-5-yl]-3-[4-(4-morpholin-4-yl-7H-pyrrolo[2,3-d]pyrimidin-6-yl)phenyl]propan-2-one;1-[4-(5-morpholin-4-ylimidazo[1,2-a]pyridin-2-yl)phenyl]-3-(3-pyridin-3-yl-1H-pyrazol-5-yl)propan-2-one;1-[4-(4-morpholin-4-yl-1H-imidazo[4,5-c]pyridin-2-yl)phenyl]-3-(3-pyridin-3-yl-1H-pyrazol-5-yl)propan-2-one;1-[4-(4-morpholin-4-yl-7H-pyrrolo[2,3-d]pyrimidin-6-yl)phenyl]-3-(3-pyridin-4-yl-1H-pyrazol-5-yl)propan-2-one;1-[4-(5-morpholin-4-yl-[1,2,4]triazolo[1,5-c]pyrimidin-2-yl)phenyl]-3-(3-pyridin-3-yl-1H-pyrazol-5-yl)propan-2-one has a molecular weight of 3445.92 g/mol, XLogP of 25.80, 50 rotatable bonds, 12 hydrogen bond donors, and 52 hydrogen bond acceptors.
Where does this data come from?
All data for 1-[3-(2-fluoro-4-pyridinyl)-1H-pyrazol-5-yl]-3-[4-(4-morpholin-4-yl-7H-pyrrolo[2,3-d]pyrimidin-6-yl)phenyl]propan-2-one;1-[3-[6-(2-hydroxypropan-2-yl)-3-pyridinyl]-1H-pyrazol-5-yl]-3-[4-(5-morpholin-4-ylimidazo[1,2-a]pyridin-2-yl)phenyl]propan-2-one;1-[3-(2-methyl-4-pyridinyl)-1H-pyrazol-5-yl]-3-[4-(4-morpholin-4-yl-7H-pyrrolo[2,3-d]pyrimidin-6-yl)phenyl]propan-2-one;1-[4-(5-morpholin-4-ylimidazo[1,2-a]pyridin-2-yl)phenyl]-3-(3-pyridin-3-yl-1H-pyrazol-5-yl)propan-2-one;1-[4-(4-morpholin-4-yl-1H-imidazo[4,5-c]pyridin-2-yl)phenyl]-3-(3-pyridin-3-yl-1H-pyrazol-5-yl)propan-2-one;1-[4-(4-morpholin-4-yl-7H-pyrrolo[2,3-d]pyrimidin-6-yl)phenyl]-3-(3-pyridin-4-yl-1H-pyrazol-5-yl)propan-2-one;1-[4-(5-morpholin-4-yl-[1,2,4]triazolo[1,5-c]pyrimidin-2-yl)phenyl]-3-(3-pyridin-3-yl-1H-pyrazol-5-yl)propan-2-one is sourced from PubChem (CID 163906028), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).