4-[6-[6-[(6-methoxy-3-pyridinyl)methyl]-3,6-diazabicyclo[3.1.1]heptan-3-yl]-3-pyridinyl]-6-[1-(trideuteriomethyl)pyrazol-4-yl]pyrazolo[1,5-a]pyridine-3-carbonitrile;6-[[(2R)-morpholin-2-yl]methoxy]-4-[5-[6-[[4-(trideuteriomethoxy)phenyl]methyl]-3,6-diazabicyclo[3.1.1]heptan-3-yl]pyrazin-2-yl]pyrazolo[1,5-a]pyridine-3-carbonitrile;6-[[(2S)-morpholin-2-yl]methoxy]-4-[5-[6-[[4-(trideuteriomethoxy)phenyl]methyl]-3,6-diazabicyclo[3.1.1]heptan-3-yl]pyrazin-2-yl]pyrazolo[1,5-a]pyridine-3-carbonitrile;6-(morpholin-2-ylmethoxy)-4-[5-[6-[[4-(trideuteriomethoxy)phenyl]methyl]-3,6-diazabicyclo[3.1.1]heptan-3-yl]pyrazin-2-yl]pyrazolo[1,5-a]pyridine-3-carbonitrile

C119H123N33O10 — CID 163916806

About 4-[6-[6-[(6-methoxy-3-pyridinyl)methyl]-3,6-diazabicyclo[3.1.1]heptan-3-yl]-3-pyridinyl]-6-[1-(trideuteriomethyl)pyrazol-4-yl]pyrazolo[1,5-a]pyridine-3-carbonitrile;6-[[(2R)-morpholin-2-yl]methoxy]-4-[5-[6-[[4-(trideuteriomethoxy)phenyl]methyl]-3,6-diazabicyclo[3.1.1]heptan-3-yl]pyrazin-2-yl]pyrazolo[1,5-a]pyridine-3-carbonitrile;6-[[(2S)-morpholin-2-yl]methoxy]-4-[5-[6-[[4-(trideuteriomethoxy)phenyl]methyl]-3,6-diazabicyclo[3.1.1]heptan-3-yl]pyrazin-2-yl]pyrazolo[1,5-a]pyridine-3-carbonitrile;6-(morpholin-2-ylmethoxy)-4-[5-[6-[[4-(trideuteriomethoxy)phenyl]methyl]-3,6-diazabicyclo[3.1.1]heptan-3-yl]pyrazin-2-yl]pyrazolo[1,5-a]pyridine-3-carbonitrile

4-[6-[6-[(6-methoxy-3-pyridinyl)methyl]-3,6-diazabicyclo[3.1.1]heptan-3-yl]-3-pyridinyl]-6-[1-(trideuteriomethyl)pyrazol-4-yl]pyrazolo[1,5-a]pyridine-3-carbonitrile;6-[[(2R)-morpholin-2-yl]methoxy]-4-[5-[6-[[4-(trideuteriomethoxy)phenyl]methyl]-3,6-diazabicyclo[3.1.1]heptan-3-yl]pyrazin-2-yl]pyrazolo[1,5-a]pyridine-3-carbonitrile;6-[[(2S)-morpholin-2-yl]methoxy]-4-[5-[6-[[4-(trideuteriomethoxy)phenyl]methyl]-3,6-diazabicyclo[3.1.1]heptan-3-yl]pyrazin-2-yl]pyrazolo[1,5-a]pyridine-3-carbonitrile;6-(morpholin-2-ylmethoxy)-4-[5-[6-[[4-(trideuteriomethoxy)phenyl]methyl]-3,6-diazabicyclo[3.1.1]heptan-3-yl]pyrazin-2-yl]pyrazolo[1,5-a]pyridine-3-carbonitrile (PubChem CID 163916806) has the molecular formula C119H123N33O10 and a molecular weight of 2187.59 g/mol. Its IUPAC name is 4-[6-[6-[(6-methoxy-3-pyridinyl)methyl]-3,6-diazabicyclo[3.1.1]heptan-3-yl]-3-pyridinyl]-6-[1-(trideuteriomethyl)pyrazol-4-yl]pyrazolo[1,5-a]pyridine-3-carbonitrile;6-[[(2R)-morpholin-2-yl]methoxy]-4-[5-[6-[[4-(trideuteriomethoxy)phenyl]methyl]-3,6-diazabicyclo[3.1.1]heptan-3-yl]pyrazin-2-yl]pyrazolo[1,5-a]pyridine-3-carbonitrile;6-[[(2S)-morpholin-2-yl]methoxy]-4-[5-[6-[[4-(trideuteriomethoxy)phenyl]methyl]-3,6-diazabicyclo[3.1.1]heptan-3-yl]pyrazin-2-yl]pyrazolo[1,5-a]pyridine-3-carbonitrile;6-(morpholin-2-ylmethoxy)-4-[5-[6-[[4-(trideuteriomethoxy)phenyl]methyl]-3,6-diazabicyclo[3.1.1]heptan-3-yl]pyrazin-2-yl]pyrazolo[1,5-a]pyridine-3-carbonitrile.

Molecular Properties

• Compound Name: 4-[6-[6-[(6-methoxy-3-pyridinyl)methyl]-3,6-diazabicyclo[3.1.1]heptan-3-yl]-3-pyridinyl]-6-[1-(trideuteriomethyl)pyrazol-4-yl]pyrazolo[1,5-a]pyridine-3-carbonitrile;6-[[(2R)-morpholin-2-yl]methoxy]-4-[5-[6-[[4-(trideuteriomethoxy)phenyl]methyl]-3,6-diazabicyclo[3.1.1]heptan-3-yl]pyrazin-2-yl]pyrazolo[1,5-a]pyridine-3-carbonitrile;6-[[(2S)-morpholin-2-yl]methoxy]-4-[5-[6-[[4-(trideuteriomethoxy)phenyl]methyl]-3,6-diazabicyclo[3.1.1]heptan-3-yl]pyrazin-2-yl]pyrazolo[1,5-a]pyridine-3-carbonitrile;6-(morpholin-2-ylmethoxy)-4-[5-[6-[[4-(trideuteriomethoxy)phenyl]methyl]-3,6-diazabicyclo[3.1.1]heptan-3-yl]pyrazin-2-yl]pyrazolo[1,5-a]pyridine-3-carbonitrile
• PubChem CID: 163916806
• Molecular Formula: C119H123N33O10
• Molecular Weight: 2187.59 g/mol
• Exact Mass: 2186.09
• IUPAC Name: 4-[6-[6-[(6-methoxy-3-pyridinyl)methyl]-3,6-diazabicyclo[3.1.1]heptan-3-yl]-3-pyridinyl]-6-[1-(trideuteriomethyl)pyrazol-4-yl]pyrazolo[1,5-a]pyridine-3-carbonitrile;6-[[(2R)-morpholin-2-yl]methoxy]-4-[5-[6-[[4-(trideuteriomethoxy)phenyl]methyl]-3,6-diazabicyclo[3.1.1]heptan-3-yl]pyrazin-2-yl]pyrazolo[1,5-a]pyridine-3-carbonitrile;6-[[(2S)-morpholin-2-yl]methoxy]-4-[5-[6-[[4-(trideuteriomethoxy)phenyl]methyl]-3,6-diazabicyclo[3.1.1]heptan-3-yl]pyrazin-2-yl]pyrazolo[1,5-a]pyridine-3-carbonitrile;6-(morpholin-2-ylmethoxy)-4-[5-[6-[[4-(trideuteriomethoxy)phenyl]methyl]-3,6-diazabicyclo[3.1.1]heptan-3-yl]pyrazin-2-yl]pyrazolo[1,5-a]pyridine-3-carbonitrile
• SMILES: [2H]C([2H])([2H])Oc1ccc(CN2C3CC2CN(c2cnc(-c4cc(OCC5CNCCO5)cn5ncc(C#N)c45)cn2)C3)cc1.[2H]C([2H])([2H])Oc1ccc(CN2C3CC2CN(c2cnc(-c4cc(OC[C@@H]5CNCCO5)cn5ncc(C#N)c45)cn2)C3)cc1.[2H]C([2H])([2H])Oc1ccc(CN2C3CC2CN(c2cnc(-c4cc(OC[C@H]5CNCCO5)cn5ncc(C#N)c45)cn2)C3)cc1.[2H]C([2H])([2H])n1cc(-c2cc(-c3ccc(N4CC5CC(C4)N5Cc4ccc(OC)nc4)nc3)c3c(C#N)cnn3c2)cn1
• InChI: InChI=1S/3C30H32N8O3.C29H27N9O/c3*1-39-24-4-2-20(3-5-24)15-37-22-8-23(37)17-36(16-22)29-14-33-28(13-34-29)27-9-25(41-19-26-12-32-6-7-40-26)18-38-30(27)21(10-31)11-35-38;1-35-15-23(13-33-35)21-7-26(29-22(9-30)12-34-38(29)16-21)20-4-5-27(31-11-20)36-17-24-8-25(18-36)37(24)14-19-3-6-28(39-2)32-10-19/h3*2-5,9,11,13-14,18,22-23,26,32H,6-8,12,15-17,19H2,1H3;3-7,10-13,15-16,24-25H,8,14,17-18H2,1-2H3/t2*22?,23?,26-;;/m10../s1/i4*1D3
• InChIKey: QWYYZFJMCMIYKE-OXWBPVRFSA-N
• XLogP: 11.04
• TPSA: 439.61 Ų
• H-Bond Donors: 3
• H-Bond Acceptors: 43
• Rotatable Bonds: 34
• Heavy Atoms: 162
• Complexity: —

Lipinski Rule of Five

3 violations

Rule	Value
MW ≤ 500	2187.59
LogP ≤ 5	11.04
H-Bond Donors ≤ 5	3
H-Bond Acceptors ≤ 10	43

Frequently Asked Questions

What is the IUPAC name of 4-[6-[6-[(6-methoxy-3-pyridinyl)methyl]-3,6-diazabicyclo[3.1.1]heptan-3-yl]-3-pyridinyl]-6-[1-(trideuteriomethyl)pyrazol-4-yl]pyrazolo[1,5-a]pyridine-3-carbonitrile;6-[[(2R)-morpholin-2-yl]methoxy]-4-[5-[6-[[4-(trideuteriomethoxy)phenyl]methyl]-3,6-diazabicyclo[3.1.1]heptan-3-yl]pyrazin-2-yl]pyrazolo[1,5-a]pyridine-3-carbonitrile;6-[[(2S)-morpholin-2-yl]methoxy]-4-[5-[6-[[4-(trideuteriomethoxy)phenyl]methyl]-3,6-diazabicyclo[3.1.1]heptan-3-yl]pyrazin-2-yl]pyrazolo[1,5-a]pyridine-3-carbonitrile;6-(morpholin-2-ylmethoxy)-4-[5-[6-[[4-(trideuteriomethoxy)phenyl]methyl]-3,6-diazabicyclo[3.1.1]heptan-3-yl]pyrazin-2-yl]pyrazolo[1,5-a]pyridine-3-carbonitrile?

The IUPAC name of 4-[6-[6-[(6-methoxy-3-pyridinyl)methyl]-3,6-diazabicyclo[3.1.1]heptan-3-yl]-3-pyridinyl]-6-[1-(trideuteriomethyl)pyrazol-4-yl]pyrazolo[1,5-a]pyridine-3-carbonitrile;6-[[(2R)-morpholin-2-yl]methoxy]-4-[5-[6-[[4-(trideuteriomethoxy)phenyl]methyl]-3,6-diazabicyclo[3.1.1]heptan-3-yl]pyrazin-2-yl]pyrazolo[1,5-a]pyridine-3-carbonitrile;6-[[(2S)-morpholin-2-yl]methoxy]-4-[5-[6-[[4-(trideuteriomethoxy)phenyl]methyl]-3,6-diazabicyclo[3.1.1]heptan-3-yl]pyrazin-2-yl]pyrazolo[1,5-a]pyridine-3-carbonitrile;6-(morpholin-2-ylmethoxy)-4-[5-[6-[[4-(trideuteriomethoxy)phenyl]methyl]-3,6-diazabicyclo[3.1.1]heptan-3-yl]pyrazin-2-yl]pyrazolo[1,5-a]pyridine-3-carbonitrile (CID 163916806) is 4-[6-[6-[(6-methoxy-3-pyridinyl)methyl]-3,6-diazabicyclo[3.1.1]heptan-3-yl]-3-pyridinyl]-6-[1-(trideuteriomethyl)pyrazol-4-yl]pyrazolo[1,5-a]pyridine-3-carbonitrile;6-[[(2R)-morpholin-2-yl]methoxy]-4-[5-[6-[[4-(trideuteriomethoxy)phenyl]methyl]-3,6-diazabicyclo[3.1.1]heptan-3-yl]pyrazin-2-yl]pyrazolo[1,5-a]pyridine-3-carbonitrile;6-[[(2S)-morpholin-2-yl]methoxy]-4-[5-[6-[[4-(trideuteriomethoxy)phenyl]methyl]-3,6-diazabicyclo[3.1.1]heptan-3-yl]pyrazin-2-yl]pyrazolo[1,5-a]pyridine-3-carbonitrile;6-(morpholin-2-ylmethoxy)-4-[5-[6-[[4-(trideuteriomethoxy)phenyl]methyl]-3,6-diazabicyclo[3.1.1]heptan-3-yl]pyrazin-2-yl]pyrazolo[1,5-a]pyridine-3-carbonitrile.

What is the SMILES notation for 4-[6-[6-[(6-methoxy-3-pyridinyl)methyl]-3,6-diazabicyclo[3.1.1]heptan-3-yl]-3-pyridinyl]-6-[1-(trideuteriomethyl)pyrazol-4-yl]pyrazolo[1,5-a]pyridine-3-carbonitrile;6-[[(2R)-morpholin-2-yl]methoxy]-4-[5-[6-[[4-(trideuteriomethoxy)phenyl]methyl]-3,6-diazabicyclo[3.1.1]heptan-3-yl]pyrazin-2-yl]pyrazolo[1,5-a]pyridine-3-carbonitrile;6-[[(2S)-morpholin-2-yl]methoxy]-4-[5-[6-[[4-(trideuteriomethoxy)phenyl]methyl]-3,6-diazabicyclo[3.1.1]heptan-3-yl]pyrazin-2-yl]pyrazolo[1,5-a]pyridine-3-carbonitrile;6-(morpholin-2-ylmethoxy)-4-[5-[6-[[4-(trideuteriomethoxy)phenyl]methyl]-3,6-diazabicyclo[3.1.1]heptan-3-yl]pyrazin-2-yl]pyrazolo[1,5-a]pyridine-3-carbonitrile?

The canonical SMILES for 4-[6-[6-[(6-methoxy-3-pyridinyl)methyl]-3,6-diazabicyclo[3.1.1]heptan-3-yl]-3-pyridinyl]-6-[1-(trideuteriomethyl)pyrazol-4-yl]pyrazolo[1,5-a]pyridine-3-carbonitrile;6-[[(2R)-morpholin-2-yl]methoxy]-4-[5-[6-[[4-(trideuteriomethoxy)phenyl]methyl]-3,6-diazabicyclo[3.1.1]heptan-3-yl]pyrazin-2-yl]pyrazolo[1,5-a]pyridine-3-carbonitrile;6-[[(2S)-morpholin-2-yl]methoxy]-4-[5-[6-[[4-(trideuteriomethoxy)phenyl]methyl]-3,6-diazabicyclo[3.1.1]heptan-3-yl]pyrazin-2-yl]pyrazolo[1,5-a]pyridine-3-carbonitrile;6-(morpholin-2-ylmethoxy)-4-[5-[6-[[4-(trideuteriomethoxy)phenyl]methyl]-3,6-diazabicyclo[3.1.1]heptan-3-yl]pyrazin-2-yl]pyrazolo[1,5-a]pyridine-3-carbonitrile is [2H]C([2H])([2H])Oc1ccc(CN2C3CC2CN(c2cnc(-c4cc(OCC5CNCCO5)cn5ncc(C#N)c45)cn2)C3)cc1.[2H]C([2H])([2H])Oc1ccc(CN2C3CC2CN(c2cnc(-c4cc(OC[C@@H]5CNCCO5)cn5ncc(C#N)c45)cn2)C3)cc1.[2H]C([2H])([2H])Oc1ccc(CN2C3CC2CN(c2cnc(-c4cc(OC[C@H]5CNCCO5)cn5ncc(C#N)c45)cn2)C3)cc1.[2H]C([2H])([2H])n1cc(-c2cc(-c3ccc(N4CC5CC(C4)N5Cc4ccc(OC)nc4)nc3)c3c(C#N)cnn3c2)cn1.

What is the InChIKey of 4-[6-[6-[(6-methoxy-3-pyridinyl)methyl]-3,6-diazabicyclo[3.1.1]heptan-3-yl]-3-pyridinyl]-6-[1-(trideuteriomethyl)pyrazol-4-yl]pyrazolo[1,5-a]pyridine-3-carbonitrile;6-[[(2R)-morpholin-2-yl]methoxy]-4-[5-[6-[[4-(trideuteriomethoxy)phenyl]methyl]-3,6-diazabicyclo[3.1.1]heptan-3-yl]pyrazin-2-yl]pyrazolo[1,5-a]pyridine-3-carbonitrile;6-[[(2S)-morpholin-2-yl]methoxy]-4-[5-[6-[[4-(trideuteriomethoxy)phenyl]methyl]-3,6-diazabicyclo[3.1.1]heptan-3-yl]pyrazin-2-yl]pyrazolo[1,5-a]pyridine-3-carbonitrile;6-(morpholin-2-ylmethoxy)-4-[5-[6-[[4-(trideuteriomethoxy)phenyl]methyl]-3,6-diazabicyclo[3.1.1]heptan-3-yl]pyrazin-2-yl]pyrazolo[1,5-a]pyridine-3-carbonitrile?

The InChIKey is QWYYZFJMCMIYKE-OXWBPVRFSA-N. The full InChI is InChI=1S/3C30H32N8O3.C29H27N9O/c3*1-39-24-4-2-20(3-5-24)15-37-22-8-23(37)17-36(16-22)29-14-33-28(13-34-29)27-9-25(41-19-26-12-32-6-7-40-26)18-38-30(27)21(10-31)11-35-38;1-35-15-23(13-33-35)21-7-26(29-22(9-30)12-34-38(29)16-21)20-4-5-27(31-11-20)36-17-24-8-25(18-36)37(24)14-19-3-6-28(39-2)32-10-19/h3*2-5,9,11,13-14,18,22-23,26,32H,6-8,12,15-17,19H2,1H3;3-7,10-13,15-16,24-25H,8,14,17-18H2,1-2H3/t2*22?,23?,26-;;/m10../s1/i4*1D3.

What are the key properties of 4-[6-[6-[(6-methoxy-3-pyridinyl)methyl]-3,6-diazabicyclo[3.1.1]heptan-3-yl]-3-pyridinyl]-6-[1-(trideuteriomethyl)pyrazol-4-yl]pyrazolo[1,5-a]pyridine-3-carbonitrile;6-[[(2R)-morpholin-2-yl]methoxy]-4-[5-[6-[[4-(trideuteriomethoxy)phenyl]methyl]-3,6-diazabicyclo[3.1.1]heptan-3-yl]pyrazin-2-yl]pyrazolo[1,5-a]pyridine-3-carbonitrile;6-[[(2S)-morpholin-2-yl]methoxy]-4-[5-[6-[[4-(trideuteriomethoxy)phenyl]methyl]-3,6-diazabicyclo[3.1.1]heptan-3-yl]pyrazin-2-yl]pyrazolo[1,5-a]pyridine-3-carbonitrile;6-(morpholin-2-ylmethoxy)-4-[5-[6-[[4-(trideuteriomethoxy)phenyl]methyl]-3,6-diazabicyclo[3.1.1]heptan-3-yl]pyrazin-2-yl]pyrazolo[1,5-a]pyridine-3-carbonitrile?

4-[6-[6-[(6-methoxy-3-pyridinyl)methyl]-3,6-diazabicyclo[3.1.1]heptan-3-yl]-3-pyridinyl]-6-[1-(trideuteriomethyl)pyrazol-4-yl]pyrazolo[1,5-a]pyridine-3-carbonitrile;6-[[(2R)-morpholin-2-yl]methoxy]-4-[5-[6-[[4-(trideuteriomethoxy)phenyl]methyl]-3,6-diazabicyclo[3.1.1]heptan-3-yl]pyrazin-2-yl]pyrazolo[1,5-a]pyridine-3-carbonitrile;6-[[(2S)-morpholin-2-yl]methoxy]-4-[5-[6-[[4-(trideuteriomethoxy)phenyl]methyl]-3,6-diazabicyclo[3.1.1]heptan-3-yl]pyrazin-2-yl]pyrazolo[1,5-a]pyridine-3-carbonitrile;6-(morpholin-2-ylmethoxy)-4-[5-[6-[[4-(trideuteriomethoxy)phenyl]methyl]-3,6-diazabicyclo[3.1.1]heptan-3-yl]pyrazin-2-yl]pyrazolo[1,5-a]pyridine-3-carbonitrile has a molecular weight of 2187.59 g/mol, XLogP of 11.04, 34 rotatable bonds, 3 hydrogen bond donors, and 43 hydrogen bond acceptors.

Where does this data come from?

All data for 4-[6-[6-[(6-methoxy-3-pyridinyl)methyl]-3,6-diazabicyclo[3.1.1]heptan-3-yl]-3-pyridinyl]-6-[1-(trideuteriomethyl)pyrazol-4-yl]pyrazolo[1,5-a]pyridine-3-carbonitrile;6-[[(2R)-morpholin-2-yl]methoxy]-4-[5-[6-[[4-(trideuteriomethoxy)phenyl]methyl]-3,6-diazabicyclo[3.1.1]heptan-3-yl]pyrazin-2-yl]pyrazolo[1,5-a]pyridine-3-carbonitrile;6-[[(2S)-morpholin-2-yl]methoxy]-4-[5-[6-[[4-(trideuteriomethoxy)phenyl]methyl]-3,6-diazabicyclo[3.1.1]heptan-3-yl]pyrazin-2-yl]pyrazolo[1,5-a]pyridine-3-carbonitrile;6-(morpholin-2-ylmethoxy)-4-[5-[6-[[4-(trideuteriomethoxy)phenyl]methyl]-3,6-diazabicyclo[3.1.1]heptan-3-yl]pyrazin-2-yl]pyrazolo[1,5-a]pyridine-3-carbonitrile is sourced from PubChem (CID 163916806), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).