2-[3-(2,3-difluorophenyl)imidazo[1,2-a]pyridin-8-yl]-5-methyl-N-(4-methylphenyl)pyridine-4-carboxamide;5-[3-(2,3-difluorophenyl)imidazo[1,2-b]pyridazin-8-yl]-N-(4-methylphenyl)-2-(trifluoromethyl)benzamide;5-[3-(2,3-difluorophenyl)pyrazolo[1,5-a]pyridin-7-yl]-N-(4-methylphenyl)-2-(trifluoromethyl)benzamide;N-(4-methylphenyl)-5-(3-pyridin-3-ylimidazo[1,2-b]pyridazin-8-yl)-2-(trifluoromethyl)benzamide

C108H73F15N16O4 — CID 163919904

IUPAC2-[3-(2,3-difluorophenyl)imidazo[1,2-a]pyridin-8-yl]-5-methyl-N-(4-methylphenyl)pyridine-4-carboxamide;5-[3-(2,3-difluorophenyl)imidazo[1,2-b]pyridazin-8-yl]-N-(4-methylphenyl)-2-(trifluoromethyl)benzamide;5-[3-(2,3-difluorophenyl)pyrazolo[1,5-a]pyridin-7-yl]-N-(4-methylphenyl)-2-(trifluoromethyl)benzamide;N-(4-methylphenyl)-5-(3-pyridin-3-ylimidazo[1,2-b]pyridazin-8-yl)-2-(trifluoromethyl)benzamide
SMILESCc1ccc(NC(=O)c2cc(-c3cccc4c(-c5cccc(F)c5F)cnn34)ccc2C(F)(F)F)cc1.Cc1ccc(NC(=O)c2cc(-c3cccn4c(-c5cccc(F)c5F)cnc34)ncc2C)cc1.Cc1ccc(NC(=O)c2cc(-c3ccnn4c(-c5cccc(F)c5F)cnc34)ccc2C(F)(F)F)cc1.Cc1ccc(NC(=O)c2cc(-c3ccnn4c(-c5cccnc5)cnc34)ccc2C(F)(F)F)cc1
InChIInChI=1S/C28H18F5N3O.C27H17F5N4O.C27H20F2N4O.C26H18F3N5O/c1-16-8-11-18(12-9-16)35-27(37)20-14-17(10-13-22(20)28(31,32)33)24-6-3-7-25-21(15-34-36(24)25)19-4-2-5-23(29)26(19)30;1-15-5-8-17(9-6-15)35-26(37)20-13-16(7-10-21(20)27(30,31)32)18-11-12-34-36-23(14-33-25(18)36)19-3-2-4-22(28)24(19)29;1-16-8-10-18(11-9-16)32-27(34)21-13-23(30-14-17(21)2)19-6-4-12-33-24(15-31-26(19)33)20-5-3-7-22(28)25(20)29;1-16-4-7-19(8-5-16)33-25(35)21-13-17(6-9-22(21)26(27,28)29)20-10-12-32-34-23(15-31-24(20)34)18-3-2-11-30-14-18/h2-15H,1H3,(H,35,37);2-14H,1H3,(H,35,37);3-15H,1-2H3,(H,32,34);2-15H,1H3,(H,33,35)
InChIKeyQZNNEZPVGDCBMK-UHFFFAOYSA-N
MW1943.85 g/mol
LogP26.70
Rot. Bonds16

About 2-[3-(2,3-difluorophenyl)imidazo[1,2-a]pyridin-8-yl]-5-methyl-N-(4-methylphenyl)pyridine-4-carboxamide;5-[3-(2,3-difluorophenyl)imidazo[1,2-b]pyridazin-8-yl]-N-(4-methylphenyl)-2-(trifluoromethyl)benzamide;5-[3-(2,3-difluorophenyl)pyrazolo[1,5-a]pyridin-7-yl]-N-(4-methylphenyl)-2-(trifluoromethyl)benzamide;N-(4-methylphenyl)-5-(3-pyridin-3-ylimidazo[1,2-b]pyridazin-8-yl)-2-(trifluoromethyl)benzamide

2-[3-(2,3-difluorophenyl)imidazo[1,2-a]pyridin-8-yl]-5-methyl-N-(4-methylphenyl)pyridine-4-carboxamide;5-[3-(2,3-difluorophenyl)imidazo[1,2-b]pyridazin-8-yl]-N-(4-methylphenyl)-2-(trifluoromethyl)benzamide;5-[3-(2,3-difluorophenyl)pyrazolo[1,5-a]pyridin-7-yl]-N-(4-methylphenyl)-2-(trifluoromethyl)benzamide;N-(4-methylphenyl)-5-(3-pyridin-3-ylimidazo[1,2-b]pyridazin-8-yl)-2-(trifluoromethyl)benzamide (PubChem CID 163919904) has the molecular formula C108H73F15N16O4 and a molecular weight of 1943.85 g/mol. Its IUPAC name is 2-[3-(2,3-difluorophenyl)imidazo[1,2-a]pyridin-8-yl]-5-methyl-N-(4-methylphenyl)pyridine-4-carboxamide;5-[3-(2,3-difluorophenyl)imidazo[1,2-b]pyridazin-8-yl]-N-(4-methylphenyl)-2-(trifluoromethyl)benzamide;5-[3-(2,3-difluorophenyl)pyrazolo[1,5-a]pyridin-7-yl]-N-(4-methylphenyl)-2-(trifluoromethyl)benzamide;N-(4-methylphenyl)-5-(3-pyridin-3-ylimidazo[1,2-b]pyridazin-8-yl)-2-(trifluoromethyl)benzamide.

Molecular Properties

Compound Name2-[3-(2,3-difluorophenyl)imidazo[1,2-a]pyridin-8-yl]-5-methyl-N-(4-methylphenyl)pyridine-4-carboxamide;5-[3-(2,3-difluorophenyl)imidazo[1,2-b]pyridazin-8-yl]-N-(4-methylphenyl)-2-(trifluoromethyl)benzamide;5-[3-(2,3-difluorophenyl)pyrazolo[1,5-a]pyridin-7-yl]-N-(4-methylphenyl)-2-(trifluoromethyl)benzamide;N-(4-methylphenyl)-5-(3-pyridin-3-ylimidazo[1,2-b]pyridazin-8-yl)-2-(trifluoromethyl)benzamide
PubChem CID163919904
Molecular FormulaC108H73F15N16O4
Molecular Weight1943.85 g/mol
Exact Mass1942.58
IUPAC Name2-[3-(2,3-difluorophenyl)imidazo[1,2-a]pyridin-8-yl]-5-methyl-N-(4-methylphenyl)pyridine-4-carboxamide;5-[3-(2,3-difluorophenyl)imidazo[1,2-b]pyridazin-8-yl]-N-(4-methylphenyl)-2-(trifluoromethyl)benzamide;5-[3-(2,3-difluorophenyl)pyrazolo[1,5-a]pyridin-7-yl]-N-(4-methylphenyl)-2-(trifluoromethyl)benzamide;N-(4-methylphenyl)-5-(3-pyridin-3-ylimidazo[1,2-b]pyridazin-8-yl)-2-(trifluoromethyl)benzamide
SMILESCc1ccc(NC(=O)c2cc(-c3cccc4c(-c5cccc(F)c5F)cnn34)ccc2C(F)(F)F)cc1.Cc1ccc(NC(=O)c2cc(-c3cccn4c(-c5cccc(F)c5F)cnc34)ncc2C)cc1.Cc1ccc(NC(=O)c2cc(-c3ccnn4c(-c5cccc(F)c5F)cnc34)ccc2C(F)(F)F)cc1.Cc1ccc(NC(=O)c2cc(-c3ccnn4c(-c5cccnc5)cnc34)ccc2C(F)(F)F)cc1
InChIInChI=1S/C28H18F5N3O.C27H17F5N4O.C27H20F2N4O.C26H18F3N5O/c1-16-8-11-18(12-9-16)35-27(37)20-14-17(10-13-22(20)28(31,32)33)24-6-3-7-25-21(15-34-36(24)25)19-4-2-5-23(29)26(19)30;1-15-5-8-17(9-6-15)35-26(37)20-13-16(7-10-21(20)27(30,31)32)18-11-12-34-36-23(14-33-25(18)36)19-3-2-4-22(28)24(19)29;1-16-8-10-18(11-9-16)32-27(34)21-13-23(30-14-17(21)2)19-6-4-12-33-24(15-31-26(19)33)20-5-3-7-22(28)25(20)29;1-16-4-7-19(8-5-16)33-25(35)21-13-17(6-9-22(21)26(27,28)29)20-10-12-32-34-23(15-31-24(20)34)18-3-2-11-30-14-18/h2-15H,1H3,(H,35,37);2-14H,1H3,(H,35,37);3-15H,1-2H3,(H,32,34);2-15H,1H3,(H,33,35)
InChIKeyQZNNEZPVGDCBMK-UHFFFAOYSA-N
XLogP26.70
TPSA237.16 Ų
H-Bond Donors4
H-Bond Acceptors16
Rotatable Bonds16
Heavy Atoms143
Complexity—

Lipinski Rule of Five

3 violations

RuleValue
MW ≤ 5001943.85
LogP ≤ 526.70
H-Bond Donors ≤ 54
H-Bond Acceptors ≤ 1016

Analyze 2-[3-(2,3-difluorophenyl)imidazo[1,2-a]pyridin-8-yl]-5-methyl-N-(4-methylphenyl)pyridine-4-carboxamide;5-[3-(2,3-difluorophenyl)imidazo[1,2-b]pyridazin-8-yl]-N-(4-methylphenyl)-2-(trifluoromethyl)benzamide;5-[3-(2,3-difluorophenyl)pyrazolo[1,5-a]pyridin-7-yl]-N-(4-methylphenyl)-2-(trifluoromethyl)benzamide;N-(4-methylphenyl)-5-(3-pyridin-3-ylimidazo[1,2-b]pyridazin-8-yl)-2-(trifluoromethyl)benzamide with MolForge

Explore ADMET properties, 3D molecular structure, drug-likeness score, and discover similar compounds using our AI-powered platform.

Launch Full Analysis

Related Compounds

N-[2-[[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-5-yl]amino]ethyl]-2-[4-[6-[6-[(2R)-2-(3-fluorophenyl)pyrrolidin-1-yl]imidazo[1,2-b]pyridazin-3-yl]-2-pyridinyl]piperazin-1-yl]acetamide
CID 146410948
2-(2,6-dioxopiperidin-3-yl)-5-[[5-[4-[6-[6-[(2R)-2-(3-fluorophenyl)pyrrolidin-1-yl]imidazo[1,2-b]pyridazin-3-yl]-2-pyridinyl]piperazin-1-yl]-5-oxopentyl]amino]isoindole-1,3-dione
CID 146411074
4-[8-amino-3-[(1R,3S)-3-(2-methyltetrazol-5-yl)cyclohexyl]imidazo[1,5-a]pyrazin-1-yl]-N-[4-(trifluoromethyl)-2-pyridinyl]benzamide
CID 137648135
2-(2,6-dioxopiperidin-3-yl)-5-[3-[4-[6-[6-[(2R)-2-(3-fluorophenyl)pyrrolidin-1-yl]imidazo[1,2-b]pyridazin-3-yl]-2-pyridinyl]piperazine-1-carbonyl]azetidin-1-yl]isoindole-1,3-dione
CID 146410596
2-(2,6-dioxopiperidin-3-yl)-5-[2-[4-[6-[6-[(2R)-2-(3-fluorophenyl)pyrrolidin-1-yl]imidazo[1,2-b]pyridazin-3-yl]-2-pyridinyl]piperazin-1-yl]ethylamino]isoindole-1,3-dione
CID 149683645
4-[8-amino-3-[(6R,8aS)-3-oxo-2,5,6,7,8,8a-hexahydro-1H-indolizin-6-yl]imidazo[1,5-a]pyrazin-1-yl]-N-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]benzamide
CID 76903330
N-[6-[3-(4-fluorophenyl)-1-methyl-5-pyridin-4-ylpyrazol-4-yl]imidazo[1,2-b]pyridazin-2-yl]-3-pyridin-3-ylbenzamide
CID 118537213
N-(6-(4-(4-Fluorophenyl)-1,2-dimethyl-1H-imidazol-5-yl)imidazo[1,2-b]pyridazin-2-yl)-2,4-dimethyl-5-(pyridin-3-yl)benzamide
CID 118538663
N-(6-(1-(1-((1H-pyrazol-5-yl)methyl)piperidin-4-yl)-4-(4-fluorophenyl)-1H-imidazol-5-yl)imidazo[1,2-b]pyridazin-2-yl)-2-fluoroisonicotinamide
CID 118539006
N-(6-(1-(1-(4-cyanobenzoyl)piperidin-4-yl)-4-(4-fluorophenyl)-1H-imidazol-5-yl)imidazo[1,2-b]pyridazin-2-yl)-2-fluoroisonicotinamide
CID 136214278
4-methyl-N-[4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]-3-(4-pyrazolo[1,5-a]pyrimidin-3-yltriazol-1-yl)benzamide
CID 71451816
N-[4-[[4-[4-[1-[2-[[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]amino]ethyl]triazol-4-yl]butanoyl]piperazin-1-yl]methyl]-3-(trifluoromethyl)phenyl]-3-(2-imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methylbenzamide
CID 156013418

Frequently Asked Questions

What is the IUPAC name of 2-[3-(2,3-difluorophenyl)imidazo[1,2-a]pyridin-8-yl]-5-methyl-N-(4-methylphenyl)pyridine-4-carboxamide;5-[3-(2,3-difluorophenyl)imidazo[1,2-b]pyridazin-8-yl]-N-(4-methylphenyl)-2-(trifluoromethyl)benzamide;5-[3-(2,3-difluorophenyl)pyrazolo[1,5-a]pyridin-7-yl]-N-(4-methylphenyl)-2-(trifluoromethyl)benzamide;N-(4-methylphenyl)-5-(3-pyridin-3-ylimidazo[1,2-b]pyridazin-8-yl)-2-(trifluoromethyl)benzamide?
The IUPAC name of 2-[3-(2,3-difluorophenyl)imidazo[1,2-a]pyridin-8-yl]-5-methyl-N-(4-methylphenyl)pyridine-4-carboxamide;5-[3-(2,3-difluorophenyl)imidazo[1,2-b]pyridazin-8-yl]-N-(4-methylphenyl)-2-(trifluoromethyl)benzamide;5-[3-(2,3-difluorophenyl)pyrazolo[1,5-a]pyridin-7-yl]-N-(4-methylphenyl)-2-(trifluoromethyl)benzamide;N-(4-methylphenyl)-5-(3-pyridin-3-ylimidazo[1,2-b]pyridazin-8-yl)-2-(trifluoromethyl)benzamide (CID 163919904) is 2-[3-(2,3-difluorophenyl)imidazo[1,2-a]pyridin-8-yl]-5-methyl-N-(4-methylphenyl)pyridine-4-carboxamide;5-[3-(2,3-difluorophenyl)imidazo[1,2-b]pyridazin-8-yl]-N-(4-methylphenyl)-2-(trifluoromethyl)benzamide;5-[3-(2,3-difluorophenyl)pyrazolo[1,5-a]pyridin-7-yl]-N-(4-methylphenyl)-2-(trifluoromethyl)benzamide;N-(4-methylphenyl)-5-(3-pyridin-3-ylimidazo[1,2-b]pyridazin-8-yl)-2-(trifluoromethyl)benzamide.
What is the SMILES notation for 2-[3-(2,3-difluorophenyl)imidazo[1,2-a]pyridin-8-yl]-5-methyl-N-(4-methylphenyl)pyridine-4-carboxamide;5-[3-(2,3-difluorophenyl)imidazo[1,2-b]pyridazin-8-yl]-N-(4-methylphenyl)-2-(trifluoromethyl)benzamide;5-[3-(2,3-difluorophenyl)pyrazolo[1,5-a]pyridin-7-yl]-N-(4-methylphenyl)-2-(trifluoromethyl)benzamide;N-(4-methylphenyl)-5-(3-pyridin-3-ylimidazo[1,2-b]pyridazin-8-yl)-2-(trifluoromethyl)benzamide?
The canonical SMILES for 2-[3-(2,3-difluorophenyl)imidazo[1,2-a]pyridin-8-yl]-5-methyl-N-(4-methylphenyl)pyridine-4-carboxamide;5-[3-(2,3-difluorophenyl)imidazo[1,2-b]pyridazin-8-yl]-N-(4-methylphenyl)-2-(trifluoromethyl)benzamide;5-[3-(2,3-difluorophenyl)pyrazolo[1,5-a]pyridin-7-yl]-N-(4-methylphenyl)-2-(trifluoromethyl)benzamide;N-(4-methylphenyl)-5-(3-pyridin-3-ylimidazo[1,2-b]pyridazin-8-yl)-2-(trifluoromethyl)benzamide is Cc1ccc(NC(=O)c2cc(-c3cccc4c(-c5cccc(F)c5F)cnn34)ccc2C(F)(F)F)cc1.Cc1ccc(NC(=O)c2cc(-c3cccn4c(-c5cccc(F)c5F)cnc34)ncc2C)cc1.Cc1ccc(NC(=O)c2cc(-c3ccnn4c(-c5cccc(F)c5F)cnc34)ccc2C(F)(F)F)cc1.Cc1ccc(NC(=O)c2cc(-c3ccnn4c(-c5cccnc5)cnc34)ccc2C(F)(F)F)cc1.
What is the InChIKey of 2-[3-(2,3-difluorophenyl)imidazo[1,2-a]pyridin-8-yl]-5-methyl-N-(4-methylphenyl)pyridine-4-carboxamide;5-[3-(2,3-difluorophenyl)imidazo[1,2-b]pyridazin-8-yl]-N-(4-methylphenyl)-2-(trifluoromethyl)benzamide;5-[3-(2,3-difluorophenyl)pyrazolo[1,5-a]pyridin-7-yl]-N-(4-methylphenyl)-2-(trifluoromethyl)benzamide;N-(4-methylphenyl)-5-(3-pyridin-3-ylimidazo[1,2-b]pyridazin-8-yl)-2-(trifluoromethyl)benzamide?
The InChIKey is QZNNEZPVGDCBMK-UHFFFAOYSA-N. The full InChI is InChI=1S/C28H18F5N3O.C27H17F5N4O.C27H20F2N4O.C26H18F3N5O/c1-16-8-11-18(12-9-16)35-27(37)20-14-17(10-13-22(20)28(31,32)33)24-6-3-7-25-21(15-34-36(24)25)19-4-2-5-23(29)26(19)30;1-15-5-8-17(9-6-15)35-26(37)20-13-16(7-10-21(20)27(30,31)32)18-11-12-34-36-23(14-33-25(18)36)19-3-2-4-22(28)24(19)29;1-16-8-10-18(11-9-16)32-27(34)21-13-23(30-14-17(21)2)19-6-4-12-33-24(15-31-26(19)33)20-5-3-7-22(28)25(20)29;1-16-4-7-19(8-5-16)33-25(35)21-13-17(6-9-22(21)26(27,28)29)20-10-12-32-34-23(15-31-24(20)34)18-3-2-11-30-14-18/h2-15H,1H3,(H,35,37);2-14H,1H3,(H,35,37);3-15H,1-2H3,(H,32,34);2-15H,1H3,(H,33,35).
What are the key properties of 2-[3-(2,3-difluorophenyl)imidazo[1,2-a]pyridin-8-yl]-5-methyl-N-(4-methylphenyl)pyridine-4-carboxamide;5-[3-(2,3-difluorophenyl)imidazo[1,2-b]pyridazin-8-yl]-N-(4-methylphenyl)-2-(trifluoromethyl)benzamide;5-[3-(2,3-difluorophenyl)pyrazolo[1,5-a]pyridin-7-yl]-N-(4-methylphenyl)-2-(trifluoromethyl)benzamide;N-(4-methylphenyl)-5-(3-pyridin-3-ylimidazo[1,2-b]pyridazin-8-yl)-2-(trifluoromethyl)benzamide?
2-[3-(2,3-difluorophenyl)imidazo[1,2-a]pyridin-8-yl]-5-methyl-N-(4-methylphenyl)pyridine-4-carboxamide;5-[3-(2,3-difluorophenyl)imidazo[1,2-b]pyridazin-8-yl]-N-(4-methylphenyl)-2-(trifluoromethyl)benzamide;5-[3-(2,3-difluorophenyl)pyrazolo[1,5-a]pyridin-7-yl]-N-(4-methylphenyl)-2-(trifluoromethyl)benzamide;N-(4-methylphenyl)-5-(3-pyridin-3-ylimidazo[1,2-b]pyridazin-8-yl)-2-(trifluoromethyl)benzamide has a molecular weight of 1943.85 g/mol, XLogP of 26.70, 16 rotatable bonds, 4 hydrogen bond donors, and 16 hydrogen bond acceptors.
Where does this data come from?
All data for 2-[3-(2,3-difluorophenyl)imidazo[1,2-a]pyridin-8-yl]-5-methyl-N-(4-methylphenyl)pyridine-4-carboxamide;5-[3-(2,3-difluorophenyl)imidazo[1,2-b]pyridazin-8-yl]-N-(4-methylphenyl)-2-(trifluoromethyl)benzamide;5-[3-(2,3-difluorophenyl)pyrazolo[1,5-a]pyridin-7-yl]-N-(4-methylphenyl)-2-(trifluoromethyl)benzamide;N-(4-methylphenyl)-5-(3-pyridin-3-ylimidazo[1,2-b]pyridazin-8-yl)-2-(trifluoromethyl)benzamide is sourced from PubChem (CID 163919904), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).