(4-chloro-1H-indol-2-yl)-[8,8-difluoro-3,3-di(propan-2-yl)-2-azaspiro[4.5]decan-2-yl]methanone;(7-chloro-1H-indol-2-yl)-[8,8-difluoro-3,3-di(propan-2-yl)-2-azaspiro[4.5]decan-2-yl]methanone;[5,5-dimethyl-2,2-di(propan-2-yl)piperidin-1-yl]-(4-methoxy-1H-indol-2-yl)methanone;[3,3-di(propan-2-yl)-3a,4,5,6,7,7a-hexahydro-1H-isoindol-2-yl]-(4-methoxy-1H-indol-2-yl)methanone;[3,3-di(propan-2-yl)-1,4,4a,5,6,7,8,8a-octahydroisoquinolin-2-yl]-(4-methoxy-1H-indol-2-yl)methanone

C120H166Cl2F4N10O8 — CID 163997047

About (4-chloro-1H-indol-2-yl)-[8,8-difluoro-3,3-di(propan-2-yl)-2-azaspiro[4.5]decan-2-yl]methanone;(7-chloro-1H-indol-2-yl)-[8,8-difluoro-3,3-di(propan-2-yl)-2-azaspiro[4.5]decan-2-yl]methanone;[5,5-dimethyl-2,2-di(propan-2-yl)piperidin-1-yl]-(4-methoxy-1H-indol-2-yl)methanone;[3,3-di(propan-2-yl)-3a,4,5,6,7,7a-hexahydro-1H-isoindol-2-yl]-(4-methoxy-1H-indol-2-yl)methanone;[3,3-di(propan-2-yl)-1,4,4a,5,6,7,8,8a-octahydroisoquinolin-2-yl]-(4-methoxy-1H-indol-2-yl)methanone

(4-chloro-1H-indol-2-yl)-[8,8-difluoro-3,3-di(propan-2-yl)-2-azaspiro[4.5]decan-2-yl]methanone;(7-chloro-1H-indol-2-yl)-[8,8-difluoro-3,3-di(propan-2-yl)-2-azaspiro[4.5]decan-2-yl]methanone;[5,5-dimethyl-2,2-di(propan-2-yl)piperidin-1-yl]-(4-methoxy-1H-indol-2-yl)methanone;[3,3-di(propan-2-yl)-3a,4,5,6,7,7a-hexahydro-1H-isoindol-2-yl]-(4-methoxy-1H-indol-2-yl)methanone;[3,3-di(propan-2-yl)-1,4,4a,5,6,7,8,8a-octahydroisoquinolin-2-yl]-(4-methoxy-1H-indol-2-yl)methanone (PubChem CID 163997047) has the molecular formula C120H166Cl2F4N10O8 and a molecular weight of 2023.61 g/mol. Its IUPAC name is (4-chloro-1H-indol-2-yl)-[8,8-difluoro-3,3-di(propan-2-yl)-2-azaspiro[4.5]decan-2-yl]methanone;(7-chloro-1H-indol-2-yl)-[8,8-difluoro-3,3-di(propan-2-yl)-2-azaspiro[4.5]decan-2-yl]methanone;[5,5-dimethyl-2,2-di(propan-2-yl)piperidin-1-yl]-(4-methoxy-1H-indol-2-yl)methanone;[3,3-di(propan-2-yl)-3a,4,5,6,7,7a-hexahydro-1H-isoindol-2-yl]-(4-methoxy-1H-indol-2-yl)methanone;[3,3-di(propan-2-yl)-1,4,4a,5,6,7,8,8a-octahydroisoquinolin-2-yl]-(4-methoxy-1H-indol-2-yl)methanone.

Molecular Properties

• Compound Name: (4-chloro-1H-indol-2-yl)-[8,8-difluoro-3,3-di(propan-2-yl)-2-azaspiro[4.5]decan-2-yl]methanone;(7-chloro-1H-indol-2-yl)-[8,8-difluoro-3,3-di(propan-2-yl)-2-azaspiro[4.5]decan-2-yl]methanone;[5,5-dimethyl-2,2-di(propan-2-yl)piperidin-1-yl]-(4-methoxy-1H-indol-2-yl)methanone;[3,3-di(propan-2-yl)-3a,4,5,6,7,7a-hexahydro-1H-isoindol-2-yl]-(4-methoxy-1H-indol-2-yl)methanone;[3,3-di(propan-2-yl)-1,4,4a,5,6,7,8,8a-octahydroisoquinolin-2-yl]-(4-methoxy-1H-indol-2-yl)methanone
• PubChem CID: 163997047
• Molecular Formula: C120H166Cl2F4N10O8
• Molecular Weight: 2023.61 g/mol
• Exact Mass: 2021.22
• IUPAC Name: (4-chloro-1H-indol-2-yl)-[8,8-difluoro-3,3-di(propan-2-yl)-2-azaspiro[4.5]decan-2-yl]methanone;(7-chloro-1H-indol-2-yl)-[8,8-difluoro-3,3-di(propan-2-yl)-2-azaspiro[4.5]decan-2-yl]methanone;[5,5-dimethyl-2,2-di(propan-2-yl)piperidin-1-yl]-(4-methoxy-1H-indol-2-yl)methanone;[3,3-di(propan-2-yl)-3a,4,5,6,7,7a-hexahydro-1H-isoindol-2-yl]-(4-methoxy-1H-indol-2-yl)methanone;[3,3-di(propan-2-yl)-1,4,4a,5,6,7,8,8a-octahydroisoquinolin-2-yl]-(4-methoxy-1H-indol-2-yl)methanone
• SMILES: CC(C)C1(C(C)C)CC2(CCC(F)(F)CC2)CN1C(=O)c1cc2c(Cl)cccc2[nH]1.CC(C)C1(C(C)C)CC2(CCC(F)(F)CC2)CN1C(=O)c1cc2cccc(Cl)c2[nH]1.COc1cccc2[nH]c(C(=O)N3CC(C)(C)CCC3(C(C)C)C(C)C)cc12.COc1cccc2[nH]c(C(=O)N3CC4CCCCC4C3(C(C)C)C(C)C)cc12.COc1cccc2[nH]c(C(=O)N3CC4CCCCC4CC3(C(C)C)C(C)C)cc12
• InChI: InChI=1S/C25H36N2O2.2C24H31ClF2N2O.C24H34N2O2.C23H34N2O2/c1-16(2)25(17(3)4)14-18-9-6-7-10-19(18)15-27(25)24(28)22-13-20-21(26-22)11-8-12-23(20)29-5;1-15(2)24(16(3)4)13-22(8-10-23(26,27)11-9-22)14-29(24)21(30)20-12-17-18(25)6-5-7-19(17)28-20;1-15(2)24(16(3)4)13-22(8-10-23(26,27)11-9-22)14-29(24)21(30)19-12-17-6-5-7-18(25)20(17)28-19;1-15(2)24(16(3)4)19-10-7-6-9-17(19)14-26(24)23(27)21-13-18-20(25-21)11-8-12-22(18)28-5;1-15(2)23(16(3)4)12-11-22(5,6)14-25(23)21(26)19-13-17-18(24-19)9-8-10-20(17)27-7/h8,11-13,16-19,26H,6-7,9-10,14-15H2,1-5H3;2*5-7,12,15-16,28H,8-11,13-14H2,1-4H3;8,11-13,15-17,19,25H,6-7,9-10,14H2,1-5H3;8-10,13,15-16,24H,11-12,14H2,1-7H3
• InChIKey: UFPRJGKHIRFKSX-UHFFFAOYSA-N
• XLogP: 30.69
• TPSA: 208.19 Ų
• H-Bond Donors: 5
• H-Bond Acceptors: 8
• Rotatable Bonds: 18
• Heavy Atoms: 144
• Complexity: —

Lipinski Rule of Five

2 violations

Rule	Value
MW ≤ 500	2023.61
LogP ≤ 5	30.69
H-Bond Donors ≤ 5	5
H-Bond Acceptors ≤ 10	8

Frequently Asked Questions

What is the IUPAC name of (4-chloro-1H-indol-2-yl)-[8,8-difluoro-3,3-di(propan-2-yl)-2-azaspiro[4.5]decan-2-yl]methanone;(7-chloro-1H-indol-2-yl)-[8,8-difluoro-3,3-di(propan-2-yl)-2-azaspiro[4.5]decan-2-yl]methanone;[5,5-dimethyl-2,2-di(propan-2-yl)piperidin-1-yl]-(4-methoxy-1H-indol-2-yl)methanone;[3,3-di(propan-2-yl)-3a,4,5,6,7,7a-hexahydro-1H-isoindol-2-yl]-(4-methoxy-1H-indol-2-yl)methanone;[3,3-di(propan-2-yl)-1,4,4a,5,6,7,8,8a-octahydroisoquinolin-2-yl]-(4-methoxy-1H-indol-2-yl)methanone?

The IUPAC name of (4-chloro-1H-indol-2-yl)-[8,8-difluoro-3,3-di(propan-2-yl)-2-azaspiro[4.5]decan-2-yl]methanone;(7-chloro-1H-indol-2-yl)-[8,8-difluoro-3,3-di(propan-2-yl)-2-azaspiro[4.5]decan-2-yl]methanone;[5,5-dimethyl-2,2-di(propan-2-yl)piperidin-1-yl]-(4-methoxy-1H-indol-2-yl)methanone;[3,3-di(propan-2-yl)-3a,4,5,6,7,7a-hexahydro-1H-isoindol-2-yl]-(4-methoxy-1H-indol-2-yl)methanone;[3,3-di(propan-2-yl)-1,4,4a,5,6,7,8,8a-octahydroisoquinolin-2-yl]-(4-methoxy-1H-indol-2-yl)methanone (CID 163997047) is (4-chloro-1H-indol-2-yl)-[8,8-difluoro-3,3-di(propan-2-yl)-2-azaspiro[4.5]decan-2-yl]methanone;(7-chloro-1H-indol-2-yl)-[8,8-difluoro-3,3-di(propan-2-yl)-2-azaspiro[4.5]decan-2-yl]methanone;[5,5-dimethyl-2,2-di(propan-2-yl)piperidin-1-yl]-(4-methoxy-1H-indol-2-yl)methanone;[3,3-di(propan-2-yl)-3a,4,5,6,7,7a-hexahydro-1H-isoindol-2-yl]-(4-methoxy-1H-indol-2-yl)methanone;[3,3-di(propan-2-yl)-1,4,4a,5,6,7,8,8a-octahydroisoquinolin-2-yl]-(4-methoxy-1H-indol-2-yl)methanone.

What is the SMILES notation for (4-chloro-1H-indol-2-yl)-[8,8-difluoro-3,3-di(propan-2-yl)-2-azaspiro[4.5]decan-2-yl]methanone;(7-chloro-1H-indol-2-yl)-[8,8-difluoro-3,3-di(propan-2-yl)-2-azaspiro[4.5]decan-2-yl]methanone;[5,5-dimethyl-2,2-di(propan-2-yl)piperidin-1-yl]-(4-methoxy-1H-indol-2-yl)methanone;[3,3-di(propan-2-yl)-3a,4,5,6,7,7a-hexahydro-1H-isoindol-2-yl]-(4-methoxy-1H-indol-2-yl)methanone;[3,3-di(propan-2-yl)-1,4,4a,5,6,7,8,8a-octahydroisoquinolin-2-yl]-(4-methoxy-1H-indol-2-yl)methanone?

The canonical SMILES for (4-chloro-1H-indol-2-yl)-[8,8-difluoro-3,3-di(propan-2-yl)-2-azaspiro[4.5]decan-2-yl]methanone;(7-chloro-1H-indol-2-yl)-[8,8-difluoro-3,3-di(propan-2-yl)-2-azaspiro[4.5]decan-2-yl]methanone;[5,5-dimethyl-2,2-di(propan-2-yl)piperidin-1-yl]-(4-methoxy-1H-indol-2-yl)methanone;[3,3-di(propan-2-yl)-3a,4,5,6,7,7a-hexahydro-1H-isoindol-2-yl]-(4-methoxy-1H-indol-2-yl)methanone;[3,3-di(propan-2-yl)-1,4,4a,5,6,7,8,8a-octahydroisoquinolin-2-yl]-(4-methoxy-1H-indol-2-yl)methanone is CC(C)C1(C(C)C)CC2(CCC(F)(F)CC2)CN1C(=O)c1cc2c(Cl)cccc2[nH]1.CC(C)C1(C(C)C)CC2(CCC(F)(F)CC2)CN1C(=O)c1cc2cccc(Cl)c2[nH]1.COc1cccc2[nH]c(C(=O)N3CC(C)(C)CCC3(C(C)C)C(C)C)cc12.COc1cccc2[nH]c(C(=O)N3CC4CCCCC4C3(C(C)C)C(C)C)cc12.COc1cccc2[nH]c(C(=O)N3CC4CCCCC4CC3(C(C)C)C(C)C)cc12.

What is the InChIKey of (4-chloro-1H-indol-2-yl)-[8,8-difluoro-3,3-di(propan-2-yl)-2-azaspiro[4.5]decan-2-yl]methanone;(7-chloro-1H-indol-2-yl)-[8,8-difluoro-3,3-di(propan-2-yl)-2-azaspiro[4.5]decan-2-yl]methanone;[5,5-dimethyl-2,2-di(propan-2-yl)piperidin-1-yl]-(4-methoxy-1H-indol-2-yl)methanone;[3,3-di(propan-2-yl)-3a,4,5,6,7,7a-hexahydro-1H-isoindol-2-yl]-(4-methoxy-1H-indol-2-yl)methanone;[3,3-di(propan-2-yl)-1,4,4a,5,6,7,8,8a-octahydroisoquinolin-2-yl]-(4-methoxy-1H-indol-2-yl)methanone?

The InChIKey is UFPRJGKHIRFKSX-UHFFFAOYSA-N. The full InChI is InChI=1S/C25H36N2O2.2C24H31ClF2N2O.C24H34N2O2.C23H34N2O2/c1-16(2)25(17(3)4)14-18-9-6-7-10-19(18)15-27(25)24(28)22-13-20-21(26-22)11-8-12-23(20)29-5;1-15(2)24(16(3)4)13-22(8-10-23(26,27)11-9-22)14-29(24)21(30)20-12-17-18(25)6-5-7-19(17)28-20;1-15(2)24(16(3)4)13-22(8-10-23(26,27)11-9-22)14-29(24)21(30)19-12-17-6-5-7-18(25)20(17)28-19;1-15(2)24(16(3)4)19-10-7-6-9-17(19)14-26(24)23(27)21-13-18-20(25-21)11-8-12-22(18)28-5;1-15(2)23(16(3)4)12-11-22(5,6)14-25(23)21(26)19-13-17-18(24-19)9-8-10-20(17)27-7/h8,11-13,16-19,26H,6-7,9-10,14-15H2,1-5H3;2*5-7,12,15-16,28H,8-11,13-14H2,1-4H3;8,11-13,15-17,19,25H,6-7,9-10,14H2,1-5H3;8-10,13,15-16,24H,11-12,14H2,1-7H3.

What are the key properties of (4-chloro-1H-indol-2-yl)-[8,8-difluoro-3,3-di(propan-2-yl)-2-azaspiro[4.5]decan-2-yl]methanone;(7-chloro-1H-indol-2-yl)-[8,8-difluoro-3,3-di(propan-2-yl)-2-azaspiro[4.5]decan-2-yl]methanone;[5,5-dimethyl-2,2-di(propan-2-yl)piperidin-1-yl]-(4-methoxy-1H-indol-2-yl)methanone;[3,3-di(propan-2-yl)-3a,4,5,6,7,7a-hexahydro-1H-isoindol-2-yl]-(4-methoxy-1H-indol-2-yl)methanone;[3,3-di(propan-2-yl)-1,4,4a,5,6,7,8,8a-octahydroisoquinolin-2-yl]-(4-methoxy-1H-indol-2-yl)methanone?

(4-chloro-1H-indol-2-yl)-[8,8-difluoro-3,3-di(propan-2-yl)-2-azaspiro[4.5]decan-2-yl]methanone;(7-chloro-1H-indol-2-yl)-[8,8-difluoro-3,3-di(propan-2-yl)-2-azaspiro[4.5]decan-2-yl]methanone;[5,5-dimethyl-2,2-di(propan-2-yl)piperidin-1-yl]-(4-methoxy-1H-indol-2-yl)methanone;[3,3-di(propan-2-yl)-3a,4,5,6,7,7a-hexahydro-1H-isoindol-2-yl]-(4-methoxy-1H-indol-2-yl)methanone;[3,3-di(propan-2-yl)-1,4,4a,5,6,7,8,8a-octahydroisoquinolin-2-yl]-(4-methoxy-1H-indol-2-yl)methanone has a molecular weight of 2023.61 g/mol, XLogP of 30.69, 18 rotatable bonds, 5 hydrogen bond donors, and 8 hydrogen bond acceptors.

Where does this data come from?

All data for (4-chloro-1H-indol-2-yl)-[8,8-difluoro-3,3-di(propan-2-yl)-2-azaspiro[4.5]decan-2-yl]methanone;(7-chloro-1H-indol-2-yl)-[8,8-difluoro-3,3-di(propan-2-yl)-2-azaspiro[4.5]decan-2-yl]methanone;[5,5-dimethyl-2,2-di(propan-2-yl)piperidin-1-yl]-(4-methoxy-1H-indol-2-yl)methanone;[3,3-di(propan-2-yl)-3a,4,5,6,7,7a-hexahydro-1H-isoindol-2-yl]-(4-methoxy-1H-indol-2-yl)methanone;[3,3-di(propan-2-yl)-1,4,4a,5,6,7,8,8a-octahydroisoquinolin-2-yl]-(4-methoxy-1H-indol-2-yl)methanone is sourced from PubChem (CID 163997047), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).