About tert-butyl (2R,4S)-4-[3-bromo-4-isocyano-5-(methylamino)pyrazol-1-yl]-2-(2-hydroxypropan-2-yl)pyrrolidine-1-carboxylate
tert-butyl (2R,4S)-4-[3-bromo-4-isocyano-5-(methylamino)pyrazol-1-yl]-2-(2-hydroxypropan-2-yl)pyrrolidine-1-carboxylate (PubChem CID 164780156) has the molecular formula C17H26BrN5O3
and a molecular weight of 428.33 g/mol. Its IUPAC name is tert-butyl (2R,4S)-4-[3-bromo-4-isocyano-5-(methylamino)pyrazol-1-yl]-2-(2-hydroxypropan-2-yl)pyrrolidine-1-carboxylate.
Molecular Properties
| Compound Name | tert-butyl (2R,4S)-4-[3-bromo-4-isocyano-5-(methylamino)pyrazol-1-yl]-2-(2-hydroxypropan-2-yl)pyrrolidine-1-carboxylate |
| PubChem CID | 164780156 |
| Molecular Formula | C17H26BrN5O3 |
| Molecular Weight | 428.33 g/mol |
| Exact Mass | 427.12 |
| IUPAC Name | tert-butyl (2R,4S)-4-[3-bromo-4-isocyano-5-(methylamino)pyrazol-1-yl]-2-(2-hydroxypropan-2-yl)pyrrolidine-1-carboxylate |
| SMILES | [C-]#[N+]c1c(Br)nn([C@H]2C[C@H](C(C)(C)O)N(C(=O)OC(C)(C)C)C2)c1NC |
| InChI | InChI=1S/C17H26BrN5O3/c1-16(2,3)26-15(24)22-9-10(8-11(22)17(4,5)25)23-14(20-7)12(19-6)13(18)21-23/h10-11,20,25H,8-9H2,1-5,7H3/t10-,11+/m0/s1 |
| InChIKey | IMIDZGHSZKRTGD-WDEREUQCSA-N |
| XLogP | 3.56 |
| TPSA | 83.98 Ų |
| H-Bond Donors | 2 |
| H-Bond Acceptors | 6 |
| Rotatable Bonds | 3 |
| Heavy Atoms | 26 |
| Complexity | — |
Lipinski Rule of Five
Passes Rule of Five
| Rule | Value |
| MW ≤ 500 | 428.33 |
| LogP ≤ 5 | 3.56 |
| H-Bond Donors ≤ 5 | 2 |
| H-Bond Acceptors ≤ 10 | 6 |
Computed Properties (RDKit)
| Structural Alerts | {'alert_name': 'Carbo_cation/anion', 'substructure': 'N/A'} |
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Frequently Asked Questions
What is the IUPAC name of tert-butyl (2R,4S)-4-[3-bromo-4-isocyano-5-(methylamino)pyrazol-1-yl]-2-(2-hydroxypropan-2-yl)pyrrolidine-1-carboxylate?
The IUPAC name of tert-butyl (2R,4S)-4-[3-bromo-4-isocyano-5-(methylamino)pyrazol-1-yl]-2-(2-hydroxypropan-2-yl)pyrrolidine-1-carboxylate (CID 164780156) is tert-butyl (2R,4S)-4-[3-bromo-4-isocyano-5-(methylamino)pyrazol-1-yl]-2-(2-hydroxypropan-2-yl)pyrrolidine-1-carboxylate.
What is the SMILES notation for tert-butyl (2R,4S)-4-[3-bromo-4-isocyano-5-(methylamino)pyrazol-1-yl]-2-(2-hydroxypropan-2-yl)pyrrolidine-1-carboxylate?
The canonical SMILES for tert-butyl (2R,4S)-4-[3-bromo-4-isocyano-5-(methylamino)pyrazol-1-yl]-2-(2-hydroxypropan-2-yl)pyrrolidine-1-carboxylate is [C-]#[N+]c1c(Br)nn([C@H]2C[C@H](C(C)(C)O)N(C(=O)OC(C)(C)C)C2)c1NC.
What is the InChIKey of tert-butyl (2R,4S)-4-[3-bromo-4-isocyano-5-(methylamino)pyrazol-1-yl]-2-(2-hydroxypropan-2-yl)pyrrolidine-1-carboxylate?
The InChIKey is IMIDZGHSZKRTGD-WDEREUQCSA-N. The full InChI is InChI=1S/C17H26BrN5O3/c1-16(2,3)26-15(24)22-9-10(8-11(22)17(4,5)25)23-14(20-7)12(19-6)13(18)21-23/h10-11,20,25H,8-9H2,1-5,7H3/t10-,11+/m0/s1.
What are the key properties of tert-butyl (2R,4S)-4-[3-bromo-4-isocyano-5-(methylamino)pyrazol-1-yl]-2-(2-hydroxypropan-2-yl)pyrrolidine-1-carboxylate?
tert-butyl (2R,4S)-4-[3-bromo-4-isocyano-5-(methylamino)pyrazol-1-yl]-2-(2-hydroxypropan-2-yl)pyrrolidine-1-carboxylate has a molecular weight of 428.33 g/mol, XLogP of 3.56, 3 rotatable bonds, 2 hydrogen bond donors, and 6 hydrogen bond acceptors.
Where does this data come from?
All data for tert-butyl (2R,4S)-4-[3-bromo-4-isocyano-5-(methylamino)pyrazol-1-yl]-2-(2-hydroxypropan-2-yl)pyrrolidine-1-carboxylate is sourced from PubChem (CID 164780156), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).