About 5-[4-[(7-ethyl-6-oxo-7H-1,5-naphthyridin-3-yl)methyl]piperazin-1-yl]-N-methyl-6-(trifluoromethyl)pyridine-2-carboxamide
5-[4-[(7-ethyl-6-oxo-7H-1,5-naphthyridin-3-yl)methyl]piperazin-1-yl]-N-methyl-6-(trifluoromethyl)pyridine-2-carboxamide (PubChem CID 164885431) has the molecular formula C23H25F3N6O2
and a molecular weight of 474.49 g/mol. Its IUPAC name is 5-[4-[(7-ethyl-6-oxo-7H-1,5-naphthyridin-3-yl)methyl]piperazin-1-yl]-N-methyl-6-(trifluoromethyl)pyridine-2-carboxamide.
Molecular Properties
| Compound Name | 5-[4-[(7-ethyl-6-oxo-7H-1,5-naphthyridin-3-yl)methyl]piperazin-1-yl]-N-methyl-6-(trifluoromethyl)pyridine-2-carboxamide |
| PubChem CID | 164885431 |
| Molecular Formula | C23H25F3N6O2 |
| Molecular Weight | 474.49 g/mol |
| Exact Mass | 474.20 |
| IUPAC Name | 5-[4-[(7-ethyl-6-oxo-7H-1,5-naphthyridin-3-yl)methyl]piperazin-1-yl]-N-methyl-6-(trifluoromethyl)pyridine-2-carboxamide |
| SMILES | CCC1C=c2ncc(CN3CCN(c4ccc(C(=O)NC)nc4C(F)(F)F)CC3)cc2=NC1=O |
| InChI | InChI=1S/C23H25F3N6O2/c1-3-15-11-17-18(30-21(15)33)10-14(12-28-17)13-31-6-8-32(9-7-31)19-5-4-16(22(34)27-2)29-20(19)23(24,25)26/h4-5,10-12,15H,3,6-9,13H2,1-2H3,(H,27,34) |
| InChIKey | ONQJCSJKJKVRBG-UHFFFAOYSA-N |
| XLogP | 1.14 |
| TPSA | 90.79 Ų |
| H-Bond Donors | 1 |
| H-Bond Acceptors | 6 |
| Rotatable Bonds | 5 |
| Heavy Atoms | 34 |
| Complexity | — |
Lipinski Rule of Five
Passes Rule of Five
| Rule | Value |
| MW ≤ 500 | 474.49 |
| LogP ≤ 5 | 1.14 |
| H-Bond Donors ≤ 5 | 1 |
| H-Bond Acceptors ≤ 10 | 6 |
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Frequently Asked Questions
What is the IUPAC name of 5-[4-[(7-ethyl-6-oxo-7H-1,5-naphthyridin-3-yl)methyl]piperazin-1-yl]-N-methyl-6-(trifluoromethyl)pyridine-2-carboxamide?
The IUPAC name of 5-[4-[(7-ethyl-6-oxo-7H-1,5-naphthyridin-3-yl)methyl]piperazin-1-yl]-N-methyl-6-(trifluoromethyl)pyridine-2-carboxamide (CID 164885431) is 5-[4-[(7-ethyl-6-oxo-7H-1,5-naphthyridin-3-yl)methyl]piperazin-1-yl]-N-methyl-6-(trifluoromethyl)pyridine-2-carboxamide.
What is the SMILES notation for 5-[4-[(7-ethyl-6-oxo-7H-1,5-naphthyridin-3-yl)methyl]piperazin-1-yl]-N-methyl-6-(trifluoromethyl)pyridine-2-carboxamide?
The canonical SMILES for 5-[4-[(7-ethyl-6-oxo-7H-1,5-naphthyridin-3-yl)methyl]piperazin-1-yl]-N-methyl-6-(trifluoromethyl)pyridine-2-carboxamide is CCC1C=c2ncc(CN3CCN(c4ccc(C(=O)NC)nc4C(F)(F)F)CC3)cc2=NC1=O.
What is the InChIKey of 5-[4-[(7-ethyl-6-oxo-7H-1,5-naphthyridin-3-yl)methyl]piperazin-1-yl]-N-methyl-6-(trifluoromethyl)pyridine-2-carboxamide?
The InChIKey is ONQJCSJKJKVRBG-UHFFFAOYSA-N. The full InChI is InChI=1S/C23H25F3N6O2/c1-3-15-11-17-18(30-21(15)33)10-14(12-28-17)13-31-6-8-32(9-7-31)19-5-4-16(22(34)27-2)29-20(19)23(24,25)26/h4-5,10-12,15H,3,6-9,13H2,1-2H3,(H,27,34).
What are the key properties of 5-[4-[(7-ethyl-6-oxo-7H-1,5-naphthyridin-3-yl)methyl]piperazin-1-yl]-N-methyl-6-(trifluoromethyl)pyridine-2-carboxamide?
5-[4-[(7-ethyl-6-oxo-7H-1,5-naphthyridin-3-yl)methyl]piperazin-1-yl]-N-methyl-6-(trifluoromethyl)pyridine-2-carboxamide has a molecular weight of 474.49 g/mol, XLogP of 1.14, 5 rotatable bonds, 1 hydrogen bond donors, and 6 hydrogen bond acceptors.
Where does this data come from?
All data for 5-[4-[(7-ethyl-6-oxo-7H-1,5-naphthyridin-3-yl)methyl]piperazin-1-yl]-N-methyl-6-(trifluoromethyl)pyridine-2-carboxamide is sourced from PubChem (CID 164885431), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).