About 3-fluoro-4-[5-[[[5-(hydroxymethyl)-2-methylsulfanylpyrimidin-4-yl]amino]methyl]-3-pyridinyl]benzenesulfonamide
3-fluoro-4-[5-[[[5-(hydroxymethyl)-2-methylsulfanylpyrimidin-4-yl]amino]methyl]-3-pyridinyl]benzenesulfonamide (PubChem CID 164926237) has the molecular formula C18H18FN5O3S2
and a molecular weight of 435.51 g/mol. Its IUPAC name is 3-fluoro-4-[5-[[[5-(hydroxymethyl)-2-methylsulfanylpyrimidin-4-yl]amino]methyl]-3-pyridinyl]benzenesulfonamide.
Molecular Properties
| Compound Name | 3-fluoro-4-[5-[[[5-(hydroxymethyl)-2-methylsulfanylpyrimidin-4-yl]amino]methyl]-3-pyridinyl]benzenesulfonamide |
| PubChem CID | 164926237 |
| Molecular Formula | C18H18FN5O3S2 |
| Molecular Weight | 435.51 g/mol |
| Exact Mass | 435.08 |
| IUPAC Name | 3-fluoro-4-[5-[[[5-(hydroxymethyl)-2-methylsulfanylpyrimidin-4-yl]amino]methyl]-3-pyridinyl]benzenesulfonamide |
| SMILES | CSc1ncc(CO)c(NCc2cncc(-c3ccc(S(N)(=O)=O)cc3F)c2)n1 |
| InChI | InChI=1S/C18H18FN5O3S2/c1-28-18-23-9-13(10-25)17(24-18)22-7-11-4-12(8-21-6-11)15-3-2-14(5-16(15)19)29(20,26)27/h2-6,8-9,25H,7,10H2,1H3,(H2,20,26,27)(H,22,23,24) |
| InChIKey | QMGLRXCGDQWMQY-UHFFFAOYSA-N |
| XLogP | 2.15 |
| TPSA | 131.09 Ų |
| H-Bond Donors | 3 |
| H-Bond Acceptors | 8 |
| Rotatable Bonds | 7 |
| Heavy Atoms | 29 |
| Complexity | — |
Lipinski Rule of Five
Passes Rule of Five
| Rule | Value |
| MW ≤ 500 | 435.51 |
| LogP ≤ 5 | 2.15 |
| H-Bond Donors ≤ 5 | 3 |
| H-Bond Acceptors ≤ 10 | 8 |
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Frequently Asked Questions
What is the IUPAC name of 3-fluoro-4-[5-[[[5-(hydroxymethyl)-2-methylsulfanylpyrimidin-4-yl]amino]methyl]-3-pyridinyl]benzenesulfonamide?
The IUPAC name of 3-fluoro-4-[5-[[[5-(hydroxymethyl)-2-methylsulfanylpyrimidin-4-yl]amino]methyl]-3-pyridinyl]benzenesulfonamide (CID 164926237) is 3-fluoro-4-[5-[[[5-(hydroxymethyl)-2-methylsulfanylpyrimidin-4-yl]amino]methyl]-3-pyridinyl]benzenesulfonamide.
What is the SMILES notation for 3-fluoro-4-[5-[[[5-(hydroxymethyl)-2-methylsulfanylpyrimidin-4-yl]amino]methyl]-3-pyridinyl]benzenesulfonamide?
The canonical SMILES for 3-fluoro-4-[5-[[[5-(hydroxymethyl)-2-methylsulfanylpyrimidin-4-yl]amino]methyl]-3-pyridinyl]benzenesulfonamide is CSc1ncc(CO)c(NCc2cncc(-c3ccc(S(N)(=O)=O)cc3F)c2)n1.
What is the InChIKey of 3-fluoro-4-[5-[[[5-(hydroxymethyl)-2-methylsulfanylpyrimidin-4-yl]amino]methyl]-3-pyridinyl]benzenesulfonamide?
The InChIKey is QMGLRXCGDQWMQY-UHFFFAOYSA-N. The full InChI is InChI=1S/C18H18FN5O3S2/c1-28-18-23-9-13(10-25)17(24-18)22-7-11-4-12(8-21-6-11)15-3-2-14(5-16(15)19)29(20,26)27/h2-6,8-9,25H,7,10H2,1H3,(H2,20,26,27)(H,22,23,24).
What are the key properties of 3-fluoro-4-[5-[[[5-(hydroxymethyl)-2-methylsulfanylpyrimidin-4-yl]amino]methyl]-3-pyridinyl]benzenesulfonamide?
3-fluoro-4-[5-[[[5-(hydroxymethyl)-2-methylsulfanylpyrimidin-4-yl]amino]methyl]-3-pyridinyl]benzenesulfonamide has a molecular weight of 435.51 g/mol, XLogP of 2.15, 7 rotatable bonds, 3 hydrogen bond donors, and 8 hydrogen bond acceptors.
Where does this data come from?
All data for 3-fluoro-4-[5-[[[5-(hydroxymethyl)-2-methylsulfanylpyrimidin-4-yl]amino]methyl]-3-pyridinyl]benzenesulfonamide is sourced from PubChem (CID 164926237), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).