N-[6-amino-4-[4-(2,2-difluoroethyl)piperazin-1-yl]-3-pyridinyl]-6-(trifluoromethyl)pyridine-2-carboxamide;4-chloro-5-nitropyridin-2-amine;N-[2-cyclopropyl-7-[4-(2,2-difluoroethyl)piperazin-1-yl]imidazo[1,2-a]pyridin-6-yl]-6-(trifluoromethyl)pyridine-2-carboxamide;1-(2,2-difluoroethyl)piperazine;4-[4-(2,2-difluoroethyl)piperazin-1-yl]-5-nitropyridin-2-amine;4-[4-(2,2-difluoroethyl)piperazin-1-yl]pyridine-2,5-diamine

C74H90ClF16N27O6 — CID 164977873

About N-[6-amino-4-[4-(2,2-difluoroethyl)piperazin-1-yl]-3-pyridinyl]-6-(trifluoromethyl)pyridine-2-carboxamide;4-chloro-5-nitropyridin-2-amine;N-[2-cyclopropyl-7-[4-(2,2-difluoroethyl)piperazin-1-yl]imidazo[1,2-a]pyridin-6-yl]-6-(trifluoromethyl)pyridine-2-carboxamide;1-(2,2-difluoroethyl)piperazine;4-[4-(2,2-difluoroethyl)piperazin-1-yl]-5-nitropyridin-2-amine;4-[4-(2,2-difluoroethyl)piperazin-1-yl]pyridine-2,5-diamine

N-[6-amino-4-[4-(2,2-difluoroethyl)piperazin-1-yl]-3-pyridinyl]-6-(trifluoromethyl)pyridine-2-carboxamide;4-chloro-5-nitropyridin-2-amine;N-[2-cyclopropyl-7-[4-(2,2-difluoroethyl)piperazin-1-yl]imidazo[1,2-a]pyridin-6-yl]-6-(trifluoromethyl)pyridine-2-carboxamide;1-(2,2-difluoroethyl)piperazine;4-[4-(2,2-difluoroethyl)piperazin-1-yl]-5-nitropyridin-2-amine;4-[4-(2,2-difluoroethyl)piperazin-1-yl]pyridine-2,5-diamine (PubChem CID 164977873) has the molecular formula C74H90ClF16N27O6 and a molecular weight of 1793.14 g/mol. Its IUPAC name is N-[6-amino-4-[4-(2,2-difluoroethyl)piperazin-1-yl]-3-pyridinyl]-6-(trifluoromethyl)pyridine-2-carboxamide;4-chloro-5-nitropyridin-2-amine;N-[2-cyclopropyl-7-[4-(2,2-difluoroethyl)piperazin-1-yl]imidazo[1,2-a]pyridin-6-yl]-6-(trifluoromethyl)pyridine-2-carboxamide;1-(2,2-difluoroethyl)piperazine;4-[4-(2,2-difluoroethyl)piperazin-1-yl]-5-nitropyridin-2-amine;4-[4-(2,2-difluoroethyl)piperazin-1-yl]pyridine-2,5-diamine.

Molecular Properties

• Compound Name: N-[6-amino-4-[4-(2,2-difluoroethyl)piperazin-1-yl]-3-pyridinyl]-6-(trifluoromethyl)pyridine-2-carboxamide;4-chloro-5-nitropyridin-2-amine;N-[2-cyclopropyl-7-[4-(2,2-difluoroethyl)piperazin-1-yl]imidazo[1,2-a]pyridin-6-yl]-6-(trifluoromethyl)pyridine-2-carboxamide;1-(2,2-difluoroethyl)piperazine;4-[4-(2,2-difluoroethyl)piperazin-1-yl]-5-nitropyridin-2-amine;4-[4-(2,2-difluoroethyl)piperazin-1-yl]pyridine-2,5-diamine
• PubChem CID: 164977873
• Molecular Formula: C74H90ClF16N27O6
• Molecular Weight: 1793.14 g/mol
• Exact Mass: 1791.70
• IUPAC Name: N-[6-amino-4-[4-(2,2-difluoroethyl)piperazin-1-yl]-3-pyridinyl]-6-(trifluoromethyl)pyridine-2-carboxamide;4-chloro-5-nitropyridin-2-amine;N-[2-cyclopropyl-7-[4-(2,2-difluoroethyl)piperazin-1-yl]imidazo[1,2-a]pyridin-6-yl]-6-(trifluoromethyl)pyridine-2-carboxamide;1-(2,2-difluoroethyl)piperazine;4-[4-(2,2-difluoroethyl)piperazin-1-yl]-5-nitropyridin-2-amine;4-[4-(2,2-difluoroethyl)piperazin-1-yl]pyridine-2,5-diamine
• SMILES: FC(F)CN1CCNCC1.Nc1cc(Cl)c([N+](=O)[O-])cn1.Nc1cc(N2CCN(CC(F)F)CC2)c(N)cn1.Nc1cc(N2CCN(CC(F)F)CC2)c(NC(=O)c2cccc(C(F)(F)F)n2)cn1.Nc1cc(N2CCN(CC(F)F)CC2)c([N+](=O)[O-])cn1.O=C(Nc1cn2cc(C3CC3)nc2cc1N1CCN(CC(F)F)CC1)c1cccc(C(F)(F)F)n1
• InChI: InChI=1S/C23H23F5N6O.C18H19F5N6O.C11H15F2N5O2.C11H17F2N5.C6H12F2N2.C5H4ClN3O2/c24-20(25)13-32-6-8-33(9-7-32)18-10-21-30-16(14-4-5-14)11-34(21)12-17(18)31-22(35)15-2-1-3-19(29-15)23(26,27)28;19-15(20)10-28-4-6-29(7-5-28)13-8-16(24)25-9-12(13)27-17(30)11-2-1-3-14(26-11)18(21,22)23;12-10(13)7-16-1-3-17(4-2-16)8-5-11(14)15-6-9(8)18(19)20;12-10(13)7-17-1-3-18(4-2-17)9-5-11(15)16-6-8(9)14;7-6(8)5-10-3-1-9-2-4-10;6-3-1-5(7)8-2-4(3)9(10)11/h1-3,10-12,14,20H,4-9,13H2,(H,31,35);1-3,8-9,15H,4-7,10H2,(H2,24,25)(H,27,30);5-6,10H,1-4,7H2,(H2,14,15);5-6,10H,1-4,7,14H2,(H2,15,16);6,9H,1-5H2;1-2H,(H2,7,8)
• InChIKey: FAXSZHWYELLTEB-UHFFFAOYSA-N
• XLogP: 9.96
• TPSA: 410.41 Ų
• H-Bond Donors: 8
• H-Bond Acceptors: 29
• Rotatable Bonds: 21
• Heavy Atoms: 124
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	1793.14
LogP ≤ 5	9.96
H-Bond Donors ≤ 5	8
H-Bond Acceptors ≤ 10	29

Computed Properties (RDKit)

• Structural Alerts: {'alert_name': 'nitro_group', 'substructure': 'N/A'}, {'alert_name': 'Oxygen-nitrogen_single_bond', 'substructure': 'N/A'}

Frequently Asked Questions

What is the IUPAC name of N-[6-amino-4-[4-(2,2-difluoroethyl)piperazin-1-yl]-3-pyridinyl]-6-(trifluoromethyl)pyridine-2-carboxamide;4-chloro-5-nitropyridin-2-amine;N-[2-cyclopropyl-7-[4-(2,2-difluoroethyl)piperazin-1-yl]imidazo[1,2-a]pyridin-6-yl]-6-(trifluoromethyl)pyridine-2-carboxamide;1-(2,2-difluoroethyl)piperazine;4-[4-(2,2-difluoroethyl)piperazin-1-yl]-5-nitropyridin-2-amine;4-[4-(2,2-difluoroethyl)piperazin-1-yl]pyridine-2,5-diamine?

The IUPAC name of N-[6-amino-4-[4-(2,2-difluoroethyl)piperazin-1-yl]-3-pyridinyl]-6-(trifluoromethyl)pyridine-2-carboxamide;4-chloro-5-nitropyridin-2-amine;N-[2-cyclopropyl-7-[4-(2,2-difluoroethyl)piperazin-1-yl]imidazo[1,2-a]pyridin-6-yl]-6-(trifluoromethyl)pyridine-2-carboxamide;1-(2,2-difluoroethyl)piperazine;4-[4-(2,2-difluoroethyl)piperazin-1-yl]-5-nitropyridin-2-amine;4-[4-(2,2-difluoroethyl)piperazin-1-yl]pyridine-2,5-diamine (CID 164977873) is N-[6-amino-4-[4-(2,2-difluoroethyl)piperazin-1-yl]-3-pyridinyl]-6-(trifluoromethyl)pyridine-2-carboxamide;4-chloro-5-nitropyridin-2-amine;N-[2-cyclopropyl-7-[4-(2,2-difluoroethyl)piperazin-1-yl]imidazo[1,2-a]pyridin-6-yl]-6-(trifluoromethyl)pyridine-2-carboxamide;1-(2,2-difluoroethyl)piperazine;4-[4-(2,2-difluoroethyl)piperazin-1-yl]-5-nitropyridin-2-amine;4-[4-(2,2-difluoroethyl)piperazin-1-yl]pyridine-2,5-diamine.

What is the SMILES notation for N-[6-amino-4-[4-(2,2-difluoroethyl)piperazin-1-yl]-3-pyridinyl]-6-(trifluoromethyl)pyridine-2-carboxamide;4-chloro-5-nitropyridin-2-amine;N-[2-cyclopropyl-7-[4-(2,2-difluoroethyl)piperazin-1-yl]imidazo[1,2-a]pyridin-6-yl]-6-(trifluoromethyl)pyridine-2-carboxamide;1-(2,2-difluoroethyl)piperazine;4-[4-(2,2-difluoroethyl)piperazin-1-yl]-5-nitropyridin-2-amine;4-[4-(2,2-difluoroethyl)piperazin-1-yl]pyridine-2,5-diamine?

The canonical SMILES for N-[6-amino-4-[4-(2,2-difluoroethyl)piperazin-1-yl]-3-pyridinyl]-6-(trifluoromethyl)pyridine-2-carboxamide;4-chloro-5-nitropyridin-2-amine;N-[2-cyclopropyl-7-[4-(2,2-difluoroethyl)piperazin-1-yl]imidazo[1,2-a]pyridin-6-yl]-6-(trifluoromethyl)pyridine-2-carboxamide;1-(2,2-difluoroethyl)piperazine;4-[4-(2,2-difluoroethyl)piperazin-1-yl]-5-nitropyridin-2-amine;4-[4-(2,2-difluoroethyl)piperazin-1-yl]pyridine-2,5-diamine is FC(F)CN1CCNCC1.Nc1cc(Cl)c([N+](=O)[O-])cn1.Nc1cc(N2CCN(CC(F)F)CC2)c(N)cn1.Nc1cc(N2CCN(CC(F)F)CC2)c(NC(=O)c2cccc(C(F)(F)F)n2)cn1.Nc1cc(N2CCN(CC(F)F)CC2)c([N+](=O)[O-])cn1.O=C(Nc1cn2cc(C3CC3)nc2cc1N1CCN(CC(F)F)CC1)c1cccc(C(F)(F)F)n1.

What is the InChIKey of N-[6-amino-4-[4-(2,2-difluoroethyl)piperazin-1-yl]-3-pyridinyl]-6-(trifluoromethyl)pyridine-2-carboxamide;4-chloro-5-nitropyridin-2-amine;N-[2-cyclopropyl-7-[4-(2,2-difluoroethyl)piperazin-1-yl]imidazo[1,2-a]pyridin-6-yl]-6-(trifluoromethyl)pyridine-2-carboxamide;1-(2,2-difluoroethyl)piperazine;4-[4-(2,2-difluoroethyl)piperazin-1-yl]-5-nitropyridin-2-amine;4-[4-(2,2-difluoroethyl)piperazin-1-yl]pyridine-2,5-diamine?

The InChIKey is FAXSZHWYELLTEB-UHFFFAOYSA-N. The full InChI is InChI=1S/C23H23F5N6O.C18H19F5N6O.C11H15F2N5O2.C11H17F2N5.C6H12F2N2.C5H4ClN3O2/c24-20(25)13-32-6-8-33(9-7-32)18-10-21-30-16(14-4-5-14)11-34(21)12-17(18)31-22(35)15-2-1-3-19(29-15)23(26,27)28;19-15(20)10-28-4-6-29(7-5-28)13-8-16(24)25-9-12(13)27-17(30)11-2-1-3-14(26-11)18(21,22)23;12-10(13)7-16-1-3-17(4-2-16)8-5-11(14)15-6-9(8)18(19)20;12-10(13)7-17-1-3-18(4-2-17)9-5-11(15)16-6-8(9)14;7-6(8)5-10-3-1-9-2-4-10;6-3-1-5(7)8-2-4(3)9(10)11/h1-3,10-12,14,20H,4-9,13H2,(H,31,35);1-3,8-9,15H,4-7,10H2,(H2,24,25)(H,27,30);5-6,10H,1-4,7H2,(H2,14,15);5-6,10H,1-4,7,14H2,(H2,15,16);6,9H,1-5H2;1-2H,(H2,7,8).

What are the key properties of N-[6-amino-4-[4-(2,2-difluoroethyl)piperazin-1-yl]-3-pyridinyl]-6-(trifluoromethyl)pyridine-2-carboxamide;4-chloro-5-nitropyridin-2-amine;N-[2-cyclopropyl-7-[4-(2,2-difluoroethyl)piperazin-1-yl]imidazo[1,2-a]pyridin-6-yl]-6-(trifluoromethyl)pyridine-2-carboxamide;1-(2,2-difluoroethyl)piperazine;4-[4-(2,2-difluoroethyl)piperazin-1-yl]-5-nitropyridin-2-amine;4-[4-(2,2-difluoroethyl)piperazin-1-yl]pyridine-2,5-diamine?

N-[6-amino-4-[4-(2,2-difluoroethyl)piperazin-1-yl]-3-pyridinyl]-6-(trifluoromethyl)pyridine-2-carboxamide;4-chloro-5-nitropyridin-2-amine;N-[2-cyclopropyl-7-[4-(2,2-difluoroethyl)piperazin-1-yl]imidazo[1,2-a]pyridin-6-yl]-6-(trifluoromethyl)pyridine-2-carboxamide;1-(2,2-difluoroethyl)piperazine;4-[4-(2,2-difluoroethyl)piperazin-1-yl]-5-nitropyridin-2-amine;4-[4-(2,2-difluoroethyl)piperazin-1-yl]pyridine-2,5-diamine has a molecular weight of 1793.14 g/mol, XLogP of 9.96, 21 rotatable bonds, 8 hydrogen bond donors, and 29 hydrogen bond acceptors.

Where does this data come from?

All data for N-[6-amino-4-[4-(2,2-difluoroethyl)piperazin-1-yl]-3-pyridinyl]-6-(trifluoromethyl)pyridine-2-carboxamide;4-chloro-5-nitropyridin-2-amine;N-[2-cyclopropyl-7-[4-(2,2-difluoroethyl)piperazin-1-yl]imidazo[1,2-a]pyridin-6-yl]-6-(trifluoromethyl)pyridine-2-carboxamide;1-(2,2-difluoroethyl)piperazine;4-[4-(2,2-difluoroethyl)piperazin-1-yl]-5-nitropyridin-2-amine;4-[4-(2,2-difluoroethyl)piperazin-1-yl]pyridine-2,5-diamine is sourced from PubChem (CID 164977873), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).