1-chloro-3-[(1S)-1-[2-ethoxy-4-fluoro-5-methyl-3-[6-(trifluoromethyl)-3-pyridinyl]phenyl]ethyl]imidazo[1,5-a]pyrazin-8-amine;1-chloro-3-[(1S)-1-[4-fluoro-5-methyl-2-propan-2-yloxy-3-[6-(trifluoromethyl)-3-pyridinyl]phenyl]ethyl]imidazo[1,5-a]pyrazin-8-amine;1-chloro-3-[(1R)-1-[4-fluoro-5-methyl-2-propan-2-yloxy-3-[6-(trifluoromethyl)-3-pyridinyl]phenyl]ethyl]imidazo[1,5-a]pyrazin-8-amine

C71H64Cl3F12N15O3 — CID 164984864

IUPAC1-chloro-3-[(1S)-1-[2-ethoxy-4-fluoro-5-methyl-3-[6-(trifluoromethyl)-3-pyridinyl]phenyl]ethyl]imidazo[1,5-a]pyrazin-8-amine;1-chloro-3-[(1S)-1-[4-fluoro-5-methyl-2-propan-2-yloxy-3-[6-(trifluoromethyl)-3-pyridinyl]phenyl]ethyl]imidazo[1,5-a]pyrazin-8-amine;1-chloro-3-[(1R)-1-[4-fluoro-5-methyl-2-propan-2-yloxy-3-[6-(trifluoromethyl)-3-pyridinyl]phenyl]ethyl]imidazo[1,5-a]pyrazin-8-amine
SMILESCCOc1c([C@H](C)c2nc(Cl)c3c(N)nccn23)cc(C)c(F)c1-c1ccc(C(F)(F)F)nc1.Cc1cc([C@@H](C)c2nc(Cl)c3c(N)nccn23)c(OC(C)C)c(-c2ccc(C(F)(F)F)nc2)c1F.Cc1cc([C@H](C)c2nc(Cl)c3c(N)nccn23)c(OC(C)C)c(-c2ccc(C(F)(F)F)nc2)c1F
InChIInChI=1S/2C24H22ClF4N5O.C23H20ClF4N5O/c2*1-11(2)35-20-15(13(4)23-33-21(25)19-22(30)31-7-8-34(19)23)9-12(3)18(26)17(20)14-5-6-16(32-10-14)24(27,28)29;1-4-34-19-14(12(3)22-32-20(24)18-21(29)30-7-8-33(18)22)9-11(2)17(25)16(19)13-5-6-15(31-10-13)23(26,27)28/h2*5-11,13H,1-4H3,(H2,30,31);5-10,12H,4H2,1-3H3,(H2,29,30)/t2*13-;12-/m100/s1
InChIKeyFZYGHYMUNZVDSW-LGHMKSSSSA-N
MW1509.73 g/mol
LogP18.91
Rot. Bonds15

About 1-chloro-3-[(1S)-1-[2-ethoxy-4-fluoro-5-methyl-3-[6-(trifluoromethyl)-3-pyridinyl]phenyl]ethyl]imidazo[1,5-a]pyrazin-8-amine;1-chloro-3-[(1S)-1-[4-fluoro-5-methyl-2-propan-2-yloxy-3-[6-(trifluoromethyl)-3-pyridinyl]phenyl]ethyl]imidazo[1,5-a]pyrazin-8-amine;1-chloro-3-[(1R)-1-[4-fluoro-5-methyl-2-propan-2-yloxy-3-[6-(trifluoromethyl)-3-pyridinyl]phenyl]ethyl]imidazo[1,5-a]pyrazin-8-amine

1-chloro-3-[(1S)-1-[2-ethoxy-4-fluoro-5-methyl-3-[6-(trifluoromethyl)-3-pyridinyl]phenyl]ethyl]imidazo[1,5-a]pyrazin-8-amine;1-chloro-3-[(1S)-1-[4-fluoro-5-methyl-2-propan-2-yloxy-3-[6-(trifluoromethyl)-3-pyridinyl]phenyl]ethyl]imidazo[1,5-a]pyrazin-8-amine;1-chloro-3-[(1R)-1-[4-fluoro-5-methyl-2-propan-2-yloxy-3-[6-(trifluoromethyl)-3-pyridinyl]phenyl]ethyl]imidazo[1,5-a]pyrazin-8-amine (PubChem CID 164984864) has the molecular formula C71H64Cl3F12N15O3 and a molecular weight of 1509.73 g/mol. Its IUPAC name is 1-chloro-3-[(1S)-1-[2-ethoxy-4-fluoro-5-methyl-3-[6-(trifluoromethyl)-3-pyridinyl]phenyl]ethyl]imidazo[1,5-a]pyrazin-8-amine;1-chloro-3-[(1S)-1-[4-fluoro-5-methyl-2-propan-2-yloxy-3-[6-(trifluoromethyl)-3-pyridinyl]phenyl]ethyl]imidazo[1,5-a]pyrazin-8-amine;1-chloro-3-[(1R)-1-[4-fluoro-5-methyl-2-propan-2-yloxy-3-[6-(trifluoromethyl)-3-pyridinyl]phenyl]ethyl]imidazo[1,5-a]pyrazin-8-amine.

Molecular Properties

Compound Name1-chloro-3-[(1S)-1-[2-ethoxy-4-fluoro-5-methyl-3-[6-(trifluoromethyl)-3-pyridinyl]phenyl]ethyl]imidazo[1,5-a]pyrazin-8-amine;1-chloro-3-[(1S)-1-[4-fluoro-5-methyl-2-propan-2-yloxy-3-[6-(trifluoromethyl)-3-pyridinyl]phenyl]ethyl]imidazo[1,5-a]pyrazin-8-amine;1-chloro-3-[(1R)-1-[4-fluoro-5-methyl-2-propan-2-yloxy-3-[6-(trifluoromethyl)-3-pyridinyl]phenyl]ethyl]imidazo[1,5-a]pyrazin-8-amine
PubChem CID164984864
Molecular FormulaC71H64Cl3F12N15O3
Molecular Weight1509.73 g/mol
Exact Mass1507.42
IUPAC Name1-chloro-3-[(1S)-1-[2-ethoxy-4-fluoro-5-methyl-3-[6-(trifluoromethyl)-3-pyridinyl]phenyl]ethyl]imidazo[1,5-a]pyrazin-8-amine;1-chloro-3-[(1S)-1-[4-fluoro-5-methyl-2-propan-2-yloxy-3-[6-(trifluoromethyl)-3-pyridinyl]phenyl]ethyl]imidazo[1,5-a]pyrazin-8-amine;1-chloro-3-[(1R)-1-[4-fluoro-5-methyl-2-propan-2-yloxy-3-[6-(trifluoromethyl)-3-pyridinyl]phenyl]ethyl]imidazo[1,5-a]pyrazin-8-amine
SMILESCCOc1c([C@H](C)c2nc(Cl)c3c(N)nccn23)cc(C)c(F)c1-c1ccc(C(F)(F)F)nc1.Cc1cc([C@@H](C)c2nc(Cl)c3c(N)nccn23)c(OC(C)C)c(-c2ccc(C(F)(F)F)nc2)c1F.Cc1cc([C@H](C)c2nc(Cl)c3c(N)nccn23)c(OC(C)C)c(-c2ccc(C(F)(F)F)nc2)c1F
InChIInChI=1S/2C24H22ClF4N5O.C23H20ClF4N5O/c2*1-11(2)35-20-15(13(4)23-33-21(25)19-22(30)31-7-8-34(19)23)9-12(3)18(26)17(20)14-5-6-16(32-10-14)24(27,28)29;1-4-34-19-14(12(3)22-32-20(24)18-21(29)30-7-8-33(18)22)9-11(2)17(25)16(19)13-5-6-15(31-10-13)23(26,27)28/h2*5-11,13H,1-4H3,(H2,30,31);5-10,12H,4H2,1-3H3,(H2,29,30)/t2*13-;12-/m100/s1
InChIKeyFZYGHYMUNZVDSW-LGHMKSSSSA-N
XLogP18.91
TPSA234.99 Ų
H-Bond Donors3
H-Bond Acceptors18
Rotatable Bonds15
Heavy Atoms104
Complexity—

Lipinski Rule of Five

3 violations

RuleValue
MW ≤ 5001509.73
LogP ≤ 518.91
H-Bond Donors ≤ 53
H-Bond Acceptors ≤ 1018

Analyze 1-chloro-3-[(1S)-1-[2-ethoxy-4-fluoro-5-methyl-3-[6-(trifluoromethyl)-3-pyridinyl]phenyl]ethyl]imidazo[1,5-a]pyrazin-8-amine;1-chloro-3-[(1S)-1-[4-fluoro-5-methyl-2-propan-2-yloxy-3-[6-(trifluoromethyl)-3-pyridinyl]phenyl]ethyl]imidazo[1,5-a]pyrazin-8-amine;1-chloro-3-[(1R)-1-[4-fluoro-5-methyl-2-propan-2-yloxy-3-[6-(trifluoromethyl)-3-pyridinyl]phenyl]ethyl]imidazo[1,5-a]pyrazin-8-amine with MolForge

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Related Compounds

1-chloro-3-[1-[5-chloro-4-methyl-2-propan-2-yloxy-3-[6-(trifluoromethyl)-3-pyridinyl]phenyl]ethyl]imidazo[1,5-a]pyrazin-8-amine
CID 158479533
1-chloro-3-[1-[5-chloro-2-ethoxy-4-methyl-3-[6-(trifluoromethyl)-3-pyridinyl]phenyl]ethyl]imidazo[1,5-a]pyrazin-8-amine;1-chloro-3-[1-[2-ethoxy-5-fluoro-4-methyl-3-[6-(trifluoromethyl)-3-pyridinyl]phenyl]ethyl]imidazo[1,5-a]pyrazin-8-amine;1-chloro-3-[1-[5-fluoro-4-methyl-2-propan-2-yloxy-3-[6-(trifluoromethyl)-3-pyridinyl]phenyl]ethyl]imidazo[1,5-a]pyrazin-8-amine;3-[1-[2-ethoxy-5-fluoro-4-methyl-3-[6-(trifluoromethyl)-3-pyridinyl]phenyl]ethyl]-1-methylimidazo[1,5-a]pyrazin-8-amine
CID 165006331
1-bromo-3-[1-[5-chloro-2-ethoxy-4-methyl-3-(5-methyl-3-pyridinyl)phenyl]ethyl]imidazo[1,5-a]pyrazin-8-amine;1-bromo-3-[1-[5-chloro-4-methyl-2-propan-2-yloxy-3-[6-(trifluoromethyl)-3-pyridinyl]phenyl]ethyl]imidazo[1,5-a]pyrazin-8-amine;1-chloro-3-[1-[5-chloro-2-ethoxy-4-methyl-3-[6-(trifluoromethyl)-3-pyridinyl]phenyl]ethyl]imidazo[1,5-a]pyrazin-8-amine;1-chloro-3-[1-[5-chloro-4-methyl-2-propan-2-yloxy-3-[6-(trifluoromethyl)-3-pyridinyl]phenyl]ethyl]imidazo[1,5-a]pyrazin-8-amine
CID 158479531
1-chloro-3-[(1S)-1-[5-chloro-3-(6-chloro-3-pyridinyl)-4-methyl-2-propan-2-yloxyphenyl]ethyl]imidazo[1,5-a]pyrazin-8-amine
CID 164714245
3-[1-[5-chloro-3-(6-chloro-3-pyridinyl)-4-fluoro-2-propan-2-yloxyphenyl]ethyl]-1-methylimidazo[1,5-a]pyrazin-8-amine
CID 166769304
[5-[5-[(1S)-1-(8-amino-1-methylimidazo[1,5-a]pyrazin-3-yl)ethyl]-3-chloro-2-fluoro-6-propan-2-yloxyphenyl]-2-pyridinyl]-[(3R)-3-hydroxypyrrolidin-1-yl]methanone
CID 134600632
1-chloro-3-[1-[5-chloro-2-ethoxy-4-methyl-3-(6-methyl-1,2-dihydropyridin-3-yl)phenyl]ethyl]imidazo[1,5-a]pyrazin-8-amine
CID 163837339
1-[5-[5-[1-(8-amino-1-chloroimidazo[1,5-a]pyrazin-3-yl)ethyl]-3-chloro-2-fluoro-6-propan-2-yloxyphenyl]-2-pyridinyl]ethenol;1-bromo-3-[1-[5-chloro-3-(3,5-dimethyl-1,2-oxazol-4-yl)-2-methoxy-4-methylphenyl]ethyl]imidazo[1,5-a]pyrazin-8-amine;1-bromo-3-[1-[5-chloro-2-methoxy-3-(6-methoxy-3-pyridinyl)-4-methylphenyl]ethyl]imidazo[1,5-a]pyrazin-8-amine;1-bromo-3-[1-[5-chloro-2-methoxy-4-methyl-3-(6-methyl-3-pyridinyl)phenyl]ethyl]imidazo[1,5-a]pyrazin-8-amine
CID 160720010
5-[1-(8-amino-1-methylimidazo[1,5-a]pyrazin-3-yl)ethyl]-3-chloro-2-fluoro-6-propan-2-yloxybenzamide
CID 138462996
1-bromo-3-[1-[5-chloro-2-ethoxy-3-[6-(2-methoxyethoxy)-3-pyridinyl]-4-methylphenyl]ethyl]imidazo[1,5-a]pyrazin-8-amine
CID 134600586
4-[5-[(1R)-1-(8-amino-1-chloroimidazo[1,5-a]pyrazin-3-yl)ethyl]-3-chloro-2-fluoro-6-propan-2-yloxyphenyl]pyrrolidin-2-one
CID 161090995
2-[5-chloro-4-fluoro-2-propan-2-yloxy-3-[6-(trifluoromethyl)-3-pyridinyl]phenyl]propanoic acid
CID 134600909

Frequently Asked Questions

What is the IUPAC name of 1-chloro-3-[(1S)-1-[2-ethoxy-4-fluoro-5-methyl-3-[6-(trifluoromethyl)-3-pyridinyl]phenyl]ethyl]imidazo[1,5-a]pyrazin-8-amine;1-chloro-3-[(1S)-1-[4-fluoro-5-methyl-2-propan-2-yloxy-3-[6-(trifluoromethyl)-3-pyridinyl]phenyl]ethyl]imidazo[1,5-a]pyrazin-8-amine;1-chloro-3-[(1R)-1-[4-fluoro-5-methyl-2-propan-2-yloxy-3-[6-(trifluoromethyl)-3-pyridinyl]phenyl]ethyl]imidazo[1,5-a]pyrazin-8-amine?
The IUPAC name of 1-chloro-3-[(1S)-1-[2-ethoxy-4-fluoro-5-methyl-3-[6-(trifluoromethyl)-3-pyridinyl]phenyl]ethyl]imidazo[1,5-a]pyrazin-8-amine;1-chloro-3-[(1S)-1-[4-fluoro-5-methyl-2-propan-2-yloxy-3-[6-(trifluoromethyl)-3-pyridinyl]phenyl]ethyl]imidazo[1,5-a]pyrazin-8-amine;1-chloro-3-[(1R)-1-[4-fluoro-5-methyl-2-propan-2-yloxy-3-[6-(trifluoromethyl)-3-pyridinyl]phenyl]ethyl]imidazo[1,5-a]pyrazin-8-amine (CID 164984864) is 1-chloro-3-[(1S)-1-[2-ethoxy-4-fluoro-5-methyl-3-[6-(trifluoromethyl)-3-pyridinyl]phenyl]ethyl]imidazo[1,5-a]pyrazin-8-amine;1-chloro-3-[(1S)-1-[4-fluoro-5-methyl-2-propan-2-yloxy-3-[6-(trifluoromethyl)-3-pyridinyl]phenyl]ethyl]imidazo[1,5-a]pyrazin-8-amine;1-chloro-3-[(1R)-1-[4-fluoro-5-methyl-2-propan-2-yloxy-3-[6-(trifluoromethyl)-3-pyridinyl]phenyl]ethyl]imidazo[1,5-a]pyrazin-8-amine.
What is the SMILES notation for 1-chloro-3-[(1S)-1-[2-ethoxy-4-fluoro-5-methyl-3-[6-(trifluoromethyl)-3-pyridinyl]phenyl]ethyl]imidazo[1,5-a]pyrazin-8-amine;1-chloro-3-[(1S)-1-[4-fluoro-5-methyl-2-propan-2-yloxy-3-[6-(trifluoromethyl)-3-pyridinyl]phenyl]ethyl]imidazo[1,5-a]pyrazin-8-amine;1-chloro-3-[(1R)-1-[4-fluoro-5-methyl-2-propan-2-yloxy-3-[6-(trifluoromethyl)-3-pyridinyl]phenyl]ethyl]imidazo[1,5-a]pyrazin-8-amine?
The canonical SMILES for 1-chloro-3-[(1S)-1-[2-ethoxy-4-fluoro-5-methyl-3-[6-(trifluoromethyl)-3-pyridinyl]phenyl]ethyl]imidazo[1,5-a]pyrazin-8-amine;1-chloro-3-[(1S)-1-[4-fluoro-5-methyl-2-propan-2-yloxy-3-[6-(trifluoromethyl)-3-pyridinyl]phenyl]ethyl]imidazo[1,5-a]pyrazin-8-amine;1-chloro-3-[(1R)-1-[4-fluoro-5-methyl-2-propan-2-yloxy-3-[6-(trifluoromethyl)-3-pyridinyl]phenyl]ethyl]imidazo[1,5-a]pyrazin-8-amine is CCOc1c([C@H](C)c2nc(Cl)c3c(N)nccn23)cc(C)c(F)c1-c1ccc(C(F)(F)F)nc1.Cc1cc([C@@H](C)c2nc(Cl)c3c(N)nccn23)c(OC(C)C)c(-c2ccc(C(F)(F)F)nc2)c1F.Cc1cc([C@H](C)c2nc(Cl)c3c(N)nccn23)c(OC(C)C)c(-c2ccc(C(F)(F)F)nc2)c1F.
What is the InChIKey of 1-chloro-3-[(1S)-1-[2-ethoxy-4-fluoro-5-methyl-3-[6-(trifluoromethyl)-3-pyridinyl]phenyl]ethyl]imidazo[1,5-a]pyrazin-8-amine;1-chloro-3-[(1S)-1-[4-fluoro-5-methyl-2-propan-2-yloxy-3-[6-(trifluoromethyl)-3-pyridinyl]phenyl]ethyl]imidazo[1,5-a]pyrazin-8-amine;1-chloro-3-[(1R)-1-[4-fluoro-5-methyl-2-propan-2-yloxy-3-[6-(trifluoromethyl)-3-pyridinyl]phenyl]ethyl]imidazo[1,5-a]pyrazin-8-amine?
The InChIKey is FZYGHYMUNZVDSW-LGHMKSSSSA-N. The full InChI is InChI=1S/2C24H22ClF4N5O.C23H20ClF4N5O/c2*1-11(2)35-20-15(13(4)23-33-21(25)19-22(30)31-7-8-34(19)23)9-12(3)18(26)17(20)14-5-6-16(32-10-14)24(27,28)29;1-4-34-19-14(12(3)22-32-20(24)18-21(29)30-7-8-33(18)22)9-11(2)17(25)16(19)13-5-6-15(31-10-13)23(26,27)28/h2*5-11,13H,1-4H3,(H2,30,31);5-10,12H,4H2,1-3H3,(H2,29,30)/t2*13-;12-/m100/s1.
What are the key properties of 1-chloro-3-[(1S)-1-[2-ethoxy-4-fluoro-5-methyl-3-[6-(trifluoromethyl)-3-pyridinyl]phenyl]ethyl]imidazo[1,5-a]pyrazin-8-amine;1-chloro-3-[(1S)-1-[4-fluoro-5-methyl-2-propan-2-yloxy-3-[6-(trifluoromethyl)-3-pyridinyl]phenyl]ethyl]imidazo[1,5-a]pyrazin-8-amine;1-chloro-3-[(1R)-1-[4-fluoro-5-methyl-2-propan-2-yloxy-3-[6-(trifluoromethyl)-3-pyridinyl]phenyl]ethyl]imidazo[1,5-a]pyrazin-8-amine?
1-chloro-3-[(1S)-1-[2-ethoxy-4-fluoro-5-methyl-3-[6-(trifluoromethyl)-3-pyridinyl]phenyl]ethyl]imidazo[1,5-a]pyrazin-8-amine;1-chloro-3-[(1S)-1-[4-fluoro-5-methyl-2-propan-2-yloxy-3-[6-(trifluoromethyl)-3-pyridinyl]phenyl]ethyl]imidazo[1,5-a]pyrazin-8-amine;1-chloro-3-[(1R)-1-[4-fluoro-5-methyl-2-propan-2-yloxy-3-[6-(trifluoromethyl)-3-pyridinyl]phenyl]ethyl]imidazo[1,5-a]pyrazin-8-amine has a molecular weight of 1509.73 g/mol, XLogP of 18.91, 15 rotatable bonds, 3 hydrogen bond donors, and 18 hydrogen bond acceptors.
Where does this data come from?
All data for 1-chloro-3-[(1S)-1-[2-ethoxy-4-fluoro-5-methyl-3-[6-(trifluoromethyl)-3-pyridinyl]phenyl]ethyl]imidazo[1,5-a]pyrazin-8-amine;1-chloro-3-[(1S)-1-[4-fluoro-5-methyl-2-propan-2-yloxy-3-[6-(trifluoromethyl)-3-pyridinyl]phenyl]ethyl]imidazo[1,5-a]pyrazin-8-amine;1-chloro-3-[(1R)-1-[4-fluoro-5-methyl-2-propan-2-yloxy-3-[6-(trifluoromethyl)-3-pyridinyl]phenyl]ethyl]imidazo[1,5-a]pyrazin-8-amine is sourced from PubChem (CID 164984864), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).