8-cyclopentyl-2-[[6-[2-(dimethylamino)ethoxy]-3-pyridinyl]amino]-7-oxopyrido[2,3-d]pyrimidine-6-carbonitrile;8-cyclopentyl-7-oxo-2-[[5-piperazin-1-yl-4-(trifluoromethyl)-2-pyridinyl]amino]pyrido[2,3-d]pyrimidine-6-carbonitrile;8-cyclopentyl-7-oxo-2-[[5-(2-piperidin-1-ylethoxy)-2-pyridinyl]amino]pyrido[2,3-d]pyrimidine-6-carbonitrile;8-cyclopentyl-7-oxo-2-[[6-(2-piperidin-1-ylethoxy)-3-pyridinyl]amino]pyrido[2,3-d]pyrimidine-6-carbonitrile;8-cyclopentyl-7-oxo-2-[[5-(2-pyrrolidin-1-ylethoxy)-2-pyridinyl]amino]pyrido[2,3-d]pyrimidine-6-carbonitrile;8-cyclopentyl-7-oxo-2-[[5-(1,2,3,6-tetrahydropyridin-4-yl)-2-pyridinyl]amino]pyrido[2,3-d]pyrimidine-6-carbonitrile

C142H156F3N43O10 — CID 165002015

IUPAC8-cyclopentyl-2-[[6-[2-(dimethylamino)ethoxy]-3-pyridinyl]amino]-7-oxopyrido[2,3-d]pyrimidine-6-carbonitrile;8-cyclopentyl-7-oxo-2-[[5-piperazin-1-yl-4-(trifluoromethyl)-2-pyridinyl]amino]pyrido[2,3-d]pyrimidine-6-carbonitrile;8-cyclopentyl-7-oxo-2-[[5-(2-piperidin-1-ylethoxy)-2-pyridinyl]amino]pyrido[2,3-d]pyrimidine-6-carbonitrile;8-cyclopentyl-7-oxo-2-[[6-(2-piperidin-1-ylethoxy)-3-pyridinyl]amino]pyrido[2,3-d]pyrimidine-6-carbonitrile;8-cyclopentyl-7-oxo-2-[[5-(2-pyrrolidin-1-ylethoxy)-2-pyridinyl]amino]pyrido[2,3-d]pyrimidine-6-carbonitrile;8-cyclopentyl-7-oxo-2-[[5-(1,2,3,6-tetrahydropyridin-4-yl)-2-pyridinyl]amino]pyrido[2,3-d]pyrimidine-6-carbonitrile
SMILESCN(C)CCOc1ccc(Nc2ncc3cc(C#N)c(=O)n(C4CCCC4)c3n2)cn1.N#Cc1cc2cnc(Nc3cc(C(F)(F)F)c(N4CCNCC4)cn3)nc2n(C2CCCC2)c1=O.N#Cc1cc2cnc(Nc3ccc(C4=CCNCC4)cn3)nc2n(C2CCCC2)c1=O.N#Cc1cc2cnc(Nc3ccc(OCCN4CCCC4)cn3)nc2n(C2CCCC2)c1=O.N#Cc1cc2cnc(Nc3ccc(OCCN4CCCCC4)cn3)nc2n(C2CCCC2)c1=O.N#Cc1cc2cnc(Nc3ccc(OCCN4CCCCC4)nc3)nc2n(C2CCCC2)c1=O
InChIInChI=1S/2C25H29N7O2.C24H27N7O2.C23H23F3N8O.C23H23N7O.C22H25N7O2/c26-15-18-14-19-16-28-25(30-23(19)32(24(18)33)21-6-2-3-7-21)29-20-8-9-22(27-17-20)34-13-12-31-10-4-1-5-11-31;26-15-18-14-19-16-28-25(30-23(19)32(24(18)33)20-6-2-3-7-20)29-22-9-8-21(17-27-22)34-13-12-31-10-4-1-5-11-31;25-14-17-13-18-15-27-24(29-22(18)31(23(17)32)19-5-1-2-6-19)28-21-8-7-20(16-26-21)33-12-11-30-9-3-4-10-30;24-23(25,26)17-10-19(29-13-18(17)33-7-5-28-6-8-33)31-22-30-12-15-9-14(11-27)21(35)34(20(15)32-22)16-3-1-2-4-16;24-12-17-11-18-14-27-23(29-21(18)30(22(17)31)19-3-1-2-4-19)28-20-6-5-16(13-26-20)15-7-9-25-10-8-15;1-28(2)9-10-31-19-8-7-17(14-24-19)26-22-25-13-16-11-15(12-23)21(30)29(20(16)27-22)18-5-3-4-6-18/h8-9,14,16-17,21H,1-7,10-13H2,(H,28,29,30);8-9,14,16-17,20H,1-7,10-13H2,(H,27,28,29,30);7-8,13,15-16,19H,1-6,9-12H2,(H,26,27,28,29);9-10,12-13,16,28H,1-8H2,(H,29,30,31,32);5-7,11,13-14,19,25H,1-4,8-10H2,(H,26,27,28,29);7-8,11,13-14,18H,3-6,9-10H2,1-2H3,(H,25,26,27)
InChIKeyIJXLEVIIWOFABS-UHFFFAOYSA-N
MW2682.09 g/mol
LogP20.45
Rot. Bonds36

About 8-cyclopentyl-2-[[6-[2-(dimethylamino)ethoxy]-3-pyridinyl]amino]-7-oxopyrido[2,3-d]pyrimidine-6-carbonitrile;8-cyclopentyl-7-oxo-2-[[5-piperazin-1-yl-4-(trifluoromethyl)-2-pyridinyl]amino]pyrido[2,3-d]pyrimidine-6-carbonitrile;8-cyclopentyl-7-oxo-2-[[5-(2-piperidin-1-ylethoxy)-2-pyridinyl]amino]pyrido[2,3-d]pyrimidine-6-carbonitrile;8-cyclopentyl-7-oxo-2-[[6-(2-piperidin-1-ylethoxy)-3-pyridinyl]amino]pyrido[2,3-d]pyrimidine-6-carbonitrile;8-cyclopentyl-7-oxo-2-[[5-(2-pyrrolidin-1-ylethoxy)-2-pyridinyl]amino]pyrido[2,3-d]pyrimidine-6-carbonitrile;8-cyclopentyl-7-oxo-2-[[5-(1,2,3,6-tetrahydropyridin-4-yl)-2-pyridinyl]amino]pyrido[2,3-d]pyrimidine-6-carbonitrile

8-cyclopentyl-2-[[6-[2-(dimethylamino)ethoxy]-3-pyridinyl]amino]-7-oxopyrido[2,3-d]pyrimidine-6-carbonitrile;8-cyclopentyl-7-oxo-2-[[5-piperazin-1-yl-4-(trifluoromethyl)-2-pyridinyl]amino]pyrido[2,3-d]pyrimidine-6-carbonitrile;8-cyclopentyl-7-oxo-2-[[5-(2-piperidin-1-ylethoxy)-2-pyridinyl]amino]pyrido[2,3-d]pyrimidine-6-carbonitrile;8-cyclopentyl-7-oxo-2-[[6-(2-piperidin-1-ylethoxy)-3-pyridinyl]amino]pyrido[2,3-d]pyrimidine-6-carbonitrile;8-cyclopentyl-7-oxo-2-[[5-(2-pyrrolidin-1-ylethoxy)-2-pyridinyl]amino]pyrido[2,3-d]pyrimidine-6-carbonitrile;8-cyclopentyl-7-oxo-2-[[5-(1,2,3,6-tetrahydropyridin-4-yl)-2-pyridinyl]amino]pyrido[2,3-d]pyrimidine-6-carbonitrile (PubChem CID 165002015) has the molecular formula C142H156F3N43O10 and a molecular weight of 2682.09 g/mol. Its IUPAC name is 8-cyclopentyl-2-[[6-[2-(dimethylamino)ethoxy]-3-pyridinyl]amino]-7-oxopyrido[2,3-d]pyrimidine-6-carbonitrile;8-cyclopentyl-7-oxo-2-[[5-piperazin-1-yl-4-(trifluoromethyl)-2-pyridinyl]amino]pyrido[2,3-d]pyrimidine-6-carbonitrile;8-cyclopentyl-7-oxo-2-[[5-(2-piperidin-1-ylethoxy)-2-pyridinyl]amino]pyrido[2,3-d]pyrimidine-6-carbonitrile;8-cyclopentyl-7-oxo-2-[[6-(2-piperidin-1-ylethoxy)-3-pyridinyl]amino]pyrido[2,3-d]pyrimidine-6-carbonitrile;8-cyclopentyl-7-oxo-2-[[5-(2-pyrrolidin-1-ylethoxy)-2-pyridinyl]amino]pyrido[2,3-d]pyrimidine-6-carbonitrile;8-cyclopentyl-7-oxo-2-[[5-(1,2,3,6-tetrahydropyridin-4-yl)-2-pyridinyl]amino]pyrido[2,3-d]pyrimidine-6-carbonitrile.

Molecular Properties

Compound Name8-cyclopentyl-2-[[6-[2-(dimethylamino)ethoxy]-3-pyridinyl]amino]-7-oxopyrido[2,3-d]pyrimidine-6-carbonitrile;8-cyclopentyl-7-oxo-2-[[5-piperazin-1-yl-4-(trifluoromethyl)-2-pyridinyl]amino]pyrido[2,3-d]pyrimidine-6-carbonitrile;8-cyclopentyl-7-oxo-2-[[5-(2-piperidin-1-ylethoxy)-2-pyridinyl]amino]pyrido[2,3-d]pyrimidine-6-carbonitrile;8-cyclopentyl-7-oxo-2-[[6-(2-piperidin-1-ylethoxy)-3-pyridinyl]amino]pyrido[2,3-d]pyrimidine-6-carbonitrile;8-cyclopentyl-7-oxo-2-[[5-(2-pyrrolidin-1-ylethoxy)-2-pyridinyl]amino]pyrido[2,3-d]pyrimidine-6-carbonitrile;8-cyclopentyl-7-oxo-2-[[5-(1,2,3,6-tetrahydropyridin-4-yl)-2-pyridinyl]amino]pyrido[2,3-d]pyrimidine-6-carbonitrile
PubChem CID165002015
Molecular FormulaC142H156F3N43O10
Molecular Weight2682.09 g/mol
Exact Mass2680.30
IUPAC Name8-cyclopentyl-2-[[6-[2-(dimethylamino)ethoxy]-3-pyridinyl]amino]-7-oxopyrido[2,3-d]pyrimidine-6-carbonitrile;8-cyclopentyl-7-oxo-2-[[5-piperazin-1-yl-4-(trifluoromethyl)-2-pyridinyl]amino]pyrido[2,3-d]pyrimidine-6-carbonitrile;8-cyclopentyl-7-oxo-2-[[5-(2-piperidin-1-ylethoxy)-2-pyridinyl]amino]pyrido[2,3-d]pyrimidine-6-carbonitrile;8-cyclopentyl-7-oxo-2-[[6-(2-piperidin-1-ylethoxy)-3-pyridinyl]amino]pyrido[2,3-d]pyrimidine-6-carbonitrile;8-cyclopentyl-7-oxo-2-[[5-(2-pyrrolidin-1-ylethoxy)-2-pyridinyl]amino]pyrido[2,3-d]pyrimidine-6-carbonitrile;8-cyclopentyl-7-oxo-2-[[5-(1,2,3,6-tetrahydropyridin-4-yl)-2-pyridinyl]amino]pyrido[2,3-d]pyrimidine-6-carbonitrile
SMILESCN(C)CCOc1ccc(Nc2ncc3cc(C#N)c(=O)n(C4CCCC4)c3n2)cn1.N#Cc1cc2cnc(Nc3cc(C(F)(F)F)c(N4CCNCC4)cn3)nc2n(C2CCCC2)c1=O.N#Cc1cc2cnc(Nc3ccc(C4=CCNCC4)cn3)nc2n(C2CCCC2)c1=O.N#Cc1cc2cnc(Nc3ccc(OCCN4CCCC4)cn3)nc2n(C2CCCC2)c1=O.N#Cc1cc2cnc(Nc3ccc(OCCN4CCCCC4)cn3)nc2n(C2CCCC2)c1=O.N#Cc1cc2cnc(Nc3ccc(OCCN4CCCCC4)nc3)nc2n(C2CCCC2)c1=O
InChIInChI=1S/2C25H29N7O2.C24H27N7O2.C23H23F3N8O.C23H23N7O.C22H25N7O2/c26-15-18-14-19-16-28-25(30-23(19)32(24(18)33)21-6-2-3-7-21)29-20-8-9-22(27-17-20)34-13-12-31-10-4-1-5-11-31;26-15-18-14-19-16-28-25(30-23(19)32(24(18)33)20-6-2-3-7-20)29-22-9-8-21(17-27-22)34-13-12-31-10-4-1-5-11-31;25-14-17-13-18-15-27-24(29-22(18)31(23(17)32)19-5-1-2-6-19)28-21-8-7-20(16-26-21)33-12-11-30-9-3-4-10-30;24-23(25,26)17-10-19(29-13-18(17)33-7-5-28-6-8-33)31-22-30-12-15-9-14(11-27)21(35)34(20(15)32-22)16-3-1-2-4-16;24-12-17-11-18-14-27-23(29-21(18)30(22(17)31)19-3-1-2-4-19)28-20-6-5-16(13-26-20)15-7-9-25-10-8-15;1-28(2)9-10-31-19-8-7-17(14-24-19)26-22-25-13-16-11-15(12-23)21(30)29(20(16)27-22)18-5-3-4-6-18/h8-9,14,16-17,21H,1-7,10-13H2,(H,28,29,30);8-9,14,16-17,20H,1-7,10-13H2,(H,27,28,29,30);7-8,13,15-16,19H,1-6,9-12H2,(H,26,27,28,29);9-10,12-13,16,28H,1-8H2,(H,29,30,31,32);5-7,11,13-14,19,25H,1-4,8-10H2,(H,26,27,28,29);7-8,11,13-14,18H,3-6,9-10H2,1-2H3,(H,25,26,27)
InChIKeyIJXLEVIIWOFABS-UHFFFAOYSA-N
XLogP20.45
TPSA656.12 Ų
H-Bond Donors8
H-Bond Acceptors53
Rotatable Bonds36
Heavy Atoms198
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5002682.09
LogP ≤ 520.45
H-Bond Donors ≤ 58
H-Bond Acceptors ≤ 1053

Analyze 8-cyclopentyl-2-[[6-[2-(dimethylamino)ethoxy]-3-pyridinyl]amino]-7-oxopyrido[2,3-d]pyrimidine-6-carbonitrile;8-cyclopentyl-7-oxo-2-[[5-piperazin-1-yl-4-(trifluoromethyl)-2-pyridinyl]amino]pyrido[2,3-d]pyrimidine-6-carbonitrile;8-cyclopentyl-7-oxo-2-[[5-(2-piperidin-1-ylethoxy)-2-pyridinyl]amino]pyrido[2,3-d]pyrimidine-6-carbonitrile;8-cyclopentyl-7-oxo-2-[[6-(2-piperidin-1-ylethoxy)-3-pyridinyl]amino]pyrido[2,3-d]pyrimidine-6-carbonitrile;8-cyclopentyl-7-oxo-2-[[5-(2-pyrrolidin-1-ylethoxy)-2-pyridinyl]amino]pyrido[2,3-d]pyrimidine-6-carbonitrile;8-cyclopentyl-7-oxo-2-[[5-(1,2,3,6-tetrahydropyridin-4-yl)-2-pyridinyl]amino]pyrido[2,3-d]pyrimidine-6-carbonitrile with MolForge

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Frequently Asked Questions

What is the IUPAC name of 8-cyclopentyl-2-[[6-[2-(dimethylamino)ethoxy]-3-pyridinyl]amino]-7-oxopyrido[2,3-d]pyrimidine-6-carbonitrile;8-cyclopentyl-7-oxo-2-[[5-piperazin-1-yl-4-(trifluoromethyl)-2-pyridinyl]amino]pyrido[2,3-d]pyrimidine-6-carbonitrile;8-cyclopentyl-7-oxo-2-[[5-(2-piperidin-1-ylethoxy)-2-pyridinyl]amino]pyrido[2,3-d]pyrimidine-6-carbonitrile;8-cyclopentyl-7-oxo-2-[[6-(2-piperidin-1-ylethoxy)-3-pyridinyl]amino]pyrido[2,3-d]pyrimidine-6-carbonitrile;8-cyclopentyl-7-oxo-2-[[5-(2-pyrrolidin-1-ylethoxy)-2-pyridinyl]amino]pyrido[2,3-d]pyrimidine-6-carbonitrile;8-cyclopentyl-7-oxo-2-[[5-(1,2,3,6-tetrahydropyridin-4-yl)-2-pyridinyl]amino]pyrido[2,3-d]pyrimidine-6-carbonitrile?
The IUPAC name of 8-cyclopentyl-2-[[6-[2-(dimethylamino)ethoxy]-3-pyridinyl]amino]-7-oxopyrido[2,3-d]pyrimidine-6-carbonitrile;8-cyclopentyl-7-oxo-2-[[5-piperazin-1-yl-4-(trifluoromethyl)-2-pyridinyl]amino]pyrido[2,3-d]pyrimidine-6-carbonitrile;8-cyclopentyl-7-oxo-2-[[5-(2-piperidin-1-ylethoxy)-2-pyridinyl]amino]pyrido[2,3-d]pyrimidine-6-carbonitrile;8-cyclopentyl-7-oxo-2-[[6-(2-piperidin-1-ylethoxy)-3-pyridinyl]amino]pyrido[2,3-d]pyrimidine-6-carbonitrile;8-cyclopentyl-7-oxo-2-[[5-(2-pyrrolidin-1-ylethoxy)-2-pyridinyl]amino]pyrido[2,3-d]pyrimidine-6-carbonitrile;8-cyclopentyl-7-oxo-2-[[5-(1,2,3,6-tetrahydropyridin-4-yl)-2-pyridinyl]amino]pyrido[2,3-d]pyrimidine-6-carbonitrile (CID 165002015) is 8-cyclopentyl-2-[[6-[2-(dimethylamino)ethoxy]-3-pyridinyl]amino]-7-oxopyrido[2,3-d]pyrimidine-6-carbonitrile;8-cyclopentyl-7-oxo-2-[[5-piperazin-1-yl-4-(trifluoromethyl)-2-pyridinyl]amino]pyrido[2,3-d]pyrimidine-6-carbonitrile;8-cyclopentyl-7-oxo-2-[[5-(2-piperidin-1-ylethoxy)-2-pyridinyl]amino]pyrido[2,3-d]pyrimidine-6-carbonitrile;8-cyclopentyl-7-oxo-2-[[6-(2-piperidin-1-ylethoxy)-3-pyridinyl]amino]pyrido[2,3-d]pyrimidine-6-carbonitrile;8-cyclopentyl-7-oxo-2-[[5-(2-pyrrolidin-1-ylethoxy)-2-pyridinyl]amino]pyrido[2,3-d]pyrimidine-6-carbonitrile;8-cyclopentyl-7-oxo-2-[[5-(1,2,3,6-tetrahydropyridin-4-yl)-2-pyridinyl]amino]pyrido[2,3-d]pyrimidine-6-carbonitrile.
What is the SMILES notation for 8-cyclopentyl-2-[[6-[2-(dimethylamino)ethoxy]-3-pyridinyl]amino]-7-oxopyrido[2,3-d]pyrimidine-6-carbonitrile;8-cyclopentyl-7-oxo-2-[[5-piperazin-1-yl-4-(trifluoromethyl)-2-pyridinyl]amino]pyrido[2,3-d]pyrimidine-6-carbonitrile;8-cyclopentyl-7-oxo-2-[[5-(2-piperidin-1-ylethoxy)-2-pyridinyl]amino]pyrido[2,3-d]pyrimidine-6-carbonitrile;8-cyclopentyl-7-oxo-2-[[6-(2-piperidin-1-ylethoxy)-3-pyridinyl]amino]pyrido[2,3-d]pyrimidine-6-carbonitrile;8-cyclopentyl-7-oxo-2-[[5-(2-pyrrolidin-1-ylethoxy)-2-pyridinyl]amino]pyrido[2,3-d]pyrimidine-6-carbonitrile;8-cyclopentyl-7-oxo-2-[[5-(1,2,3,6-tetrahydropyridin-4-yl)-2-pyridinyl]amino]pyrido[2,3-d]pyrimidine-6-carbonitrile?
The canonical SMILES for 8-cyclopentyl-2-[[6-[2-(dimethylamino)ethoxy]-3-pyridinyl]amino]-7-oxopyrido[2,3-d]pyrimidine-6-carbonitrile;8-cyclopentyl-7-oxo-2-[[5-piperazin-1-yl-4-(trifluoromethyl)-2-pyridinyl]amino]pyrido[2,3-d]pyrimidine-6-carbonitrile;8-cyclopentyl-7-oxo-2-[[5-(2-piperidin-1-ylethoxy)-2-pyridinyl]amino]pyrido[2,3-d]pyrimidine-6-carbonitrile;8-cyclopentyl-7-oxo-2-[[6-(2-piperidin-1-ylethoxy)-3-pyridinyl]amino]pyrido[2,3-d]pyrimidine-6-carbonitrile;8-cyclopentyl-7-oxo-2-[[5-(2-pyrrolidin-1-ylethoxy)-2-pyridinyl]amino]pyrido[2,3-d]pyrimidine-6-carbonitrile;8-cyclopentyl-7-oxo-2-[[5-(1,2,3,6-tetrahydropyridin-4-yl)-2-pyridinyl]amino]pyrido[2,3-d]pyrimidine-6-carbonitrile is CN(C)CCOc1ccc(Nc2ncc3cc(C#N)c(=O)n(C4CCCC4)c3n2)cn1.N#Cc1cc2cnc(Nc3cc(C(F)(F)F)c(N4CCNCC4)cn3)nc2n(C2CCCC2)c1=O.N#Cc1cc2cnc(Nc3ccc(C4=CCNCC4)cn3)nc2n(C2CCCC2)c1=O.N#Cc1cc2cnc(Nc3ccc(OCCN4CCCC4)cn3)nc2n(C2CCCC2)c1=O.N#Cc1cc2cnc(Nc3ccc(OCCN4CCCCC4)cn3)nc2n(C2CCCC2)c1=O.N#Cc1cc2cnc(Nc3ccc(OCCN4CCCCC4)nc3)nc2n(C2CCCC2)c1=O.
What is the InChIKey of 8-cyclopentyl-2-[[6-[2-(dimethylamino)ethoxy]-3-pyridinyl]amino]-7-oxopyrido[2,3-d]pyrimidine-6-carbonitrile;8-cyclopentyl-7-oxo-2-[[5-piperazin-1-yl-4-(trifluoromethyl)-2-pyridinyl]amino]pyrido[2,3-d]pyrimidine-6-carbonitrile;8-cyclopentyl-7-oxo-2-[[5-(2-piperidin-1-ylethoxy)-2-pyridinyl]amino]pyrido[2,3-d]pyrimidine-6-carbonitrile;8-cyclopentyl-7-oxo-2-[[6-(2-piperidin-1-ylethoxy)-3-pyridinyl]amino]pyrido[2,3-d]pyrimidine-6-carbonitrile;8-cyclopentyl-7-oxo-2-[[5-(2-pyrrolidin-1-ylethoxy)-2-pyridinyl]amino]pyrido[2,3-d]pyrimidine-6-carbonitrile;8-cyclopentyl-7-oxo-2-[[5-(1,2,3,6-tetrahydropyridin-4-yl)-2-pyridinyl]amino]pyrido[2,3-d]pyrimidine-6-carbonitrile?
The InChIKey is IJXLEVIIWOFABS-UHFFFAOYSA-N. The full InChI is InChI=1S/2C25H29N7O2.C24H27N7O2.C23H23F3N8O.C23H23N7O.C22H25N7O2/c26-15-18-14-19-16-28-25(30-23(19)32(24(18)33)21-6-2-3-7-21)29-20-8-9-22(27-17-20)34-13-12-31-10-4-1-5-11-31;26-15-18-14-19-16-28-25(30-23(19)32(24(18)33)20-6-2-3-7-20)29-22-9-8-21(17-27-22)34-13-12-31-10-4-1-5-11-31;25-14-17-13-18-15-27-24(29-22(18)31(23(17)32)19-5-1-2-6-19)28-21-8-7-20(16-26-21)33-12-11-30-9-3-4-10-30;24-23(25,26)17-10-19(29-13-18(17)33-7-5-28-6-8-33)31-22-30-12-15-9-14(11-27)21(35)34(20(15)32-22)16-3-1-2-4-16;24-12-17-11-18-14-27-23(29-21(18)30(22(17)31)19-3-1-2-4-19)28-20-6-5-16(13-26-20)15-7-9-25-10-8-15;1-28(2)9-10-31-19-8-7-17(14-24-19)26-22-25-13-16-11-15(12-23)21(30)29(20(16)27-22)18-5-3-4-6-18/h8-9,14,16-17,21H,1-7,10-13H2,(H,28,29,30);8-9,14,16-17,20H,1-7,10-13H2,(H,27,28,29,30);7-8,13,15-16,19H,1-6,9-12H2,(H,26,27,28,29);9-10,12-13,16,28H,1-8H2,(H,29,30,31,32);5-7,11,13-14,19,25H,1-4,8-10H2,(H,26,27,28,29);7-8,11,13-14,18H,3-6,9-10H2,1-2H3,(H,25,26,27).
What are the key properties of 8-cyclopentyl-2-[[6-[2-(dimethylamino)ethoxy]-3-pyridinyl]amino]-7-oxopyrido[2,3-d]pyrimidine-6-carbonitrile;8-cyclopentyl-7-oxo-2-[[5-piperazin-1-yl-4-(trifluoromethyl)-2-pyridinyl]amino]pyrido[2,3-d]pyrimidine-6-carbonitrile;8-cyclopentyl-7-oxo-2-[[5-(2-piperidin-1-ylethoxy)-2-pyridinyl]amino]pyrido[2,3-d]pyrimidine-6-carbonitrile;8-cyclopentyl-7-oxo-2-[[6-(2-piperidin-1-ylethoxy)-3-pyridinyl]amino]pyrido[2,3-d]pyrimidine-6-carbonitrile;8-cyclopentyl-7-oxo-2-[[5-(2-pyrrolidin-1-ylethoxy)-2-pyridinyl]amino]pyrido[2,3-d]pyrimidine-6-carbonitrile;8-cyclopentyl-7-oxo-2-[[5-(1,2,3,6-tetrahydropyridin-4-yl)-2-pyridinyl]amino]pyrido[2,3-d]pyrimidine-6-carbonitrile?
8-cyclopentyl-2-[[6-[2-(dimethylamino)ethoxy]-3-pyridinyl]amino]-7-oxopyrido[2,3-d]pyrimidine-6-carbonitrile;8-cyclopentyl-7-oxo-2-[[5-piperazin-1-yl-4-(trifluoromethyl)-2-pyridinyl]amino]pyrido[2,3-d]pyrimidine-6-carbonitrile;8-cyclopentyl-7-oxo-2-[[5-(2-piperidin-1-ylethoxy)-2-pyridinyl]amino]pyrido[2,3-d]pyrimidine-6-carbonitrile;8-cyclopentyl-7-oxo-2-[[6-(2-piperidin-1-ylethoxy)-3-pyridinyl]amino]pyrido[2,3-d]pyrimidine-6-carbonitrile;8-cyclopentyl-7-oxo-2-[[5-(2-pyrrolidin-1-ylethoxy)-2-pyridinyl]amino]pyrido[2,3-d]pyrimidine-6-carbonitrile;8-cyclopentyl-7-oxo-2-[[5-(1,2,3,6-tetrahydropyridin-4-yl)-2-pyridinyl]amino]pyrido[2,3-d]pyrimidine-6-carbonitrile has a molecular weight of 2682.09 g/mol, XLogP of 20.45, 36 rotatable bonds, 8 hydrogen bond donors, and 53 hydrogen bond acceptors.
Where does this data come from?
All data for 8-cyclopentyl-2-[[6-[2-(dimethylamino)ethoxy]-3-pyridinyl]amino]-7-oxopyrido[2,3-d]pyrimidine-6-carbonitrile;8-cyclopentyl-7-oxo-2-[[5-piperazin-1-yl-4-(trifluoromethyl)-2-pyridinyl]amino]pyrido[2,3-d]pyrimidine-6-carbonitrile;8-cyclopentyl-7-oxo-2-[[5-(2-piperidin-1-ylethoxy)-2-pyridinyl]amino]pyrido[2,3-d]pyrimidine-6-carbonitrile;8-cyclopentyl-7-oxo-2-[[6-(2-piperidin-1-ylethoxy)-3-pyridinyl]amino]pyrido[2,3-d]pyrimidine-6-carbonitrile;8-cyclopentyl-7-oxo-2-[[5-(2-pyrrolidin-1-ylethoxy)-2-pyridinyl]amino]pyrido[2,3-d]pyrimidine-6-carbonitrile;8-cyclopentyl-7-oxo-2-[[5-(1,2,3,6-tetrahydropyridin-4-yl)-2-pyridinyl]amino]pyrido[2,3-d]pyrimidine-6-carbonitrile is sourced from PubChem (CID 165002015), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).