2-[6-[(5,5-dimethyl-4-azaspiro[2.5]octan-7-yl)oxy]pyridazin-3-yl]-5-(5-fluoro-1H-pyrazol-4-yl)pyridin-3-ol;2-[6-[(5,5-dimethyl-4-azaspiro[2.5]octan-7-yl)oxy]pyridazin-3-yl]-5-(1H-pyrazol-4-yl)pyridin-3-ol;2-[6-[[(3R,4R)-3-fluoro-2,2,6,6-tetramethylpiperidin-4-yl]amino]pyridazin-3-yl]-5-[6-(trideuteriomethoxy)pyrimidin-4-yl]pyridin-3-ol

C65H75F2N19O6 — CID 165003977

IUPAC2-[6-[(5,5-dimethyl-4-azaspiro[2.5]octan-7-yl)oxy]pyridazin-3-yl]-5-(5-fluoro-1H-pyrazol-4-yl)pyridin-3-ol;2-[6-[(5,5-dimethyl-4-azaspiro[2.5]octan-7-yl)oxy]pyridazin-3-yl]-5-(1H-pyrazol-4-yl)pyridin-3-ol;2-[6-[[(3R,4R)-3-fluoro-2,2,6,6-tetramethylpiperidin-4-yl]amino]pyridazin-3-yl]-5-[6-(trideuteriomethoxy)pyrimidin-4-yl]pyridin-3-ol
SMILESCC1(C)CC(Oc2ccc(-c3ncc(-c4cn[nH]c4)cc3O)nn2)CC2(CC2)N1.CC1(C)CC(Oc2ccc(-c3ncc(-c4cn[nH]c4F)cc3O)nn2)CC2(CC2)N1.[2H]C([2H])([2H])Oc1cc(-c2cnc(-c3ccc(N[C@@H]4CC(C)(C)NC(C)(C)[C@@H]4F)nn3)c(O)c2)ncn1
InChIInChI=1S/C23H28FN7O2.C21H23FN6O2.C21H24N6O2/c1-22(2)10-16(21(24)23(3,4)31-22)28-18-7-6-14(29-30-18)20-17(32)8-13(11-25-20)15-9-19(33-5)27-12-26-15;1-20(2)8-13(9-21(28-20)5-6-21)30-17-4-3-15(25-26-17)18-16(29)7-12(10-23-18)14-11-24-27-19(14)22;1-20(2)8-15(9-21(27-20)5-6-21)29-18-4-3-16(25-26-18)19-17(28)7-13(10-22-19)14-11-23-24-12-14/h6-9,11-12,16,21,31-32H,10H2,1-5H3,(H,28,30);3-4,7,10-11,13,28-29H,5-6,8-9H2,1-2H3,(H,24,27);3-4,7,10-12,15,27-28H,5-6,8-9H2,1-2H3,(H,23,24)/t16-,21-;;/m1../s1/i5D3;;
InChIKeyIRKIRALWLJWBHU-FZABGYBDSA-N
MW1259.46 g/mol
LogP9.67
Rot. Bonds14

About 2-[6-[(5,5-dimethyl-4-azaspiro[2.5]octan-7-yl)oxy]pyridazin-3-yl]-5-(5-fluoro-1H-pyrazol-4-yl)pyridin-3-ol;2-[6-[(5,5-dimethyl-4-azaspiro[2.5]octan-7-yl)oxy]pyridazin-3-yl]-5-(1H-pyrazol-4-yl)pyridin-3-ol;2-[6-[[(3R,4R)-3-fluoro-2,2,6,6-tetramethylpiperidin-4-yl]amino]pyridazin-3-yl]-5-[6-(trideuteriomethoxy)pyrimidin-4-yl]pyridin-3-ol

2-[6-[(5,5-dimethyl-4-azaspiro[2.5]octan-7-yl)oxy]pyridazin-3-yl]-5-(5-fluoro-1H-pyrazol-4-yl)pyridin-3-ol;2-[6-[(5,5-dimethyl-4-azaspiro[2.5]octan-7-yl)oxy]pyridazin-3-yl]-5-(1H-pyrazol-4-yl)pyridin-3-ol;2-[6-[[(3R,4R)-3-fluoro-2,2,6,6-tetramethylpiperidin-4-yl]amino]pyridazin-3-yl]-5-[6-(trideuteriomethoxy)pyrimidin-4-yl]pyridin-3-ol (PubChem CID 165003977) has the molecular formula C65H75F2N19O6 and a molecular weight of 1259.46 g/mol. Its IUPAC name is 2-[6-[(5,5-dimethyl-4-azaspiro[2.5]octan-7-yl)oxy]pyridazin-3-yl]-5-(5-fluoro-1H-pyrazol-4-yl)pyridin-3-ol;2-[6-[(5,5-dimethyl-4-azaspiro[2.5]octan-7-yl)oxy]pyridazin-3-yl]-5-(1H-pyrazol-4-yl)pyridin-3-ol;2-[6-[[(3R,4R)-3-fluoro-2,2,6,6-tetramethylpiperidin-4-yl]amino]pyridazin-3-yl]-5-[6-(trideuteriomethoxy)pyrimidin-4-yl]pyridin-3-ol.

Molecular Properties

Compound Name2-[6-[(5,5-dimethyl-4-azaspiro[2.5]octan-7-yl)oxy]pyridazin-3-yl]-5-(5-fluoro-1H-pyrazol-4-yl)pyridin-3-ol;2-[6-[(5,5-dimethyl-4-azaspiro[2.5]octan-7-yl)oxy]pyridazin-3-yl]-5-(1H-pyrazol-4-yl)pyridin-3-ol;2-[6-[[(3R,4R)-3-fluoro-2,2,6,6-tetramethylpiperidin-4-yl]amino]pyridazin-3-yl]-5-[6-(trideuteriomethoxy)pyrimidin-4-yl]pyridin-3-ol
PubChem CID165003977
Molecular FormulaC65H75F2N19O6
Molecular Weight1259.46 g/mol
Exact Mass1258.63
IUPAC Name2-[6-[(5,5-dimethyl-4-azaspiro[2.5]octan-7-yl)oxy]pyridazin-3-yl]-5-(5-fluoro-1H-pyrazol-4-yl)pyridin-3-ol;2-[6-[(5,5-dimethyl-4-azaspiro[2.5]octan-7-yl)oxy]pyridazin-3-yl]-5-(1H-pyrazol-4-yl)pyridin-3-ol;2-[6-[[(3R,4R)-3-fluoro-2,2,6,6-tetramethylpiperidin-4-yl]amino]pyridazin-3-yl]-5-[6-(trideuteriomethoxy)pyrimidin-4-yl]pyridin-3-ol
SMILESCC1(C)CC(Oc2ccc(-c3ncc(-c4cn[nH]c4)cc3O)nn2)CC2(CC2)N1.CC1(C)CC(Oc2ccc(-c3ncc(-c4cn[nH]c4F)cc3O)nn2)CC2(CC2)N1.[2H]C([2H])([2H])Oc1cc(-c2cnc(-c3ccc(N[C@@H]4CC(C)(C)NC(C)(C)[C@@H]4F)nn3)c(O)c2)ncn1
InChIInChI=1S/C23H28FN7O2.C21H23FN6O2.C21H24N6O2/c1-22(2)10-16(21(24)23(3,4)31-22)28-18-7-6-14(29-30-18)20-17(32)8-13(11-25-20)15-9-19(33-5)27-12-26-15;1-20(2)8-13(9-21(28-20)5-6-21)30-17-4-3-15(25-26-17)18-16(29)7-12(10-23-18)14-11-24-27-19(14)22;1-20(2)8-15(9-21(27-20)5-6-21)29-18-4-3-16(25-26-18)19-17(28)7-13(10-22-19)14-11-23-24-12-14/h6-9,11-12,16,21,31-32H,10H2,1-5H3,(H,28,30);3-4,7,10-11,13,28-29H,5-6,8-9H2,1-2H3,(H,24,27);3-4,7,10-12,15,27-28H,5-6,8-9H2,1-2H3,(H,23,24)/t16-,21-;;/m1../s1/i5D3;;
InChIKeyIRKIRALWLJWBHU-FZABGYBDSA-N
XLogP9.67
TPSA335.65 Ų
H-Bond Donors9
H-Bond Acceptors23
Rotatable Bonds14
Heavy Atoms92
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5001259.46
LogP ≤ 59.67
H-Bond Donors ≤ 59
H-Bond Acceptors ≤ 1023

Analyze 2-[6-[(5,5-dimethyl-4-azaspiro[2.5]octan-7-yl)oxy]pyridazin-3-yl]-5-(5-fluoro-1H-pyrazol-4-yl)pyridin-3-ol;2-[6-[(5,5-dimethyl-4-azaspiro[2.5]octan-7-yl)oxy]pyridazin-3-yl]-5-(1H-pyrazol-4-yl)pyridin-3-ol;2-[6-[[(3R,4R)-3-fluoro-2,2,6,6-tetramethylpiperidin-4-yl]amino]pyridazin-3-yl]-5-[6-(trideuteriomethoxy)pyrimidin-4-yl]pyridin-3-ol with MolForge

Explore ADMET properties, 3D molecular structure, drug-likeness score, and discover similar compounds using our AI-powered platform.

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Related Compounds

(3R)-4-[4-(difluoromethoxy)-8-(1H-pyrazol-5-yl)-1,7-naphthyridin-2-yl]-3-methylmorpholine;2-[2-morpholin-4-yl-8-(1H-pyrazol-5-yl)-1,7-naphthyridin-4-yl]propan-2-ol
CID 118869642
3-fluoro-5-[2-[5-(5-piperidin-4-yloxy-3-pyridinyl)-1H-pyrazolo[3,4-c]pyridin-3-yl]-1H-imidazo[4,5-c]pyridin-4-yl]phenol
CID 136944650
N-[3-fluoro-5-[2-[5-(5-piperidin-4-yloxy-3-pyridinyl)-2H-pyrazolo[3,4-b]pyridin-3-yl]-1H-imidazo[4,5-c]pyridin-4-yl]phenyl]-N',N'-dimethylethane-1,2-diamine
CID 136945780
2-[3-fluoro-5-[2-[5-(5-piperidin-4-yloxy-3-pyridinyl)-2H-pyrazolo[3,4-b]pyridin-3-yl]-1H-imidazo[4,5-c]pyridin-4-yl]phenoxy]-N,N-dimethylethanamine
CID 136945826
3-fluoro-5-[2-[5-(5-piperidin-4-yloxy-3-pyridinyl)-2H-pyrazolo[3,4-b]pyridin-3-yl]-1H-imidazo[4,5-c]pyridin-4-yl]phenol
CID 136945917
3-[7-(3-fluoro-5-methoxyphenyl)-1H-imidazo[4,5-b]pyridin-2-yl]-5-(5-piperidin-4-yloxy-3-pyridinyl)-2H-pyrazolo[3,4-b]pyridine
CID 136946058
3-[4-(3-fluoro-5-methoxyphenyl)-1H-imidazo[4,5-c]pyridin-2-yl]-5-(5-piperidin-4-yloxy-3-pyridinyl)-2H-pyrazolo[3,4-b]pyridine
CID 136946316
3-fluoro-5-[2-[5-(5-piperidin-4-yloxy-3-pyridinyl)-1H-pyrazolo[3,4-c]pyridin-3-yl]-3H-imidazo[4,5-c]pyridin-7-yl]phenol
CID 137002170
2-[3-fluoro-5-[2-[5-(5-piperidin-4-yloxy-3-pyridinyl)-1H-pyrazolo[4,3-b]pyridin-3-yl]-3H-imidazo[4,5-c]pyridin-7-yl]phenoxy]-N,N-dimethylethanamine
CID 137033561
5-[3-[4-[3-[2-(dimethylamino)ethoxy]-5-fluorophenyl]-1H-pyrrolo[2,3-b]pyridin-2-yl]-2H-pyrazolo[3,4-b]pyridin-5-yl]pyridin-3-ol
CID 137034060
N-[3-fluoro-5-[2-[5-(5-piperidin-4-yloxy-3-pyridinyl)-2H-pyrazolo[3,4-b]pyridin-3-yl]-1H-pyrrolo[2,3-b]pyridin-4-yl]phenyl]-N',N'-dimethylethane-1,2-diamine
CID 137038224
3-[2-[5-(5-cyclohexyloxy-3-pyridinyl)-2H-pyrazolo[3,4-b]pyridin-3-yl]-1H-pyrrolo[2,3-b]pyridin-4-yl]-5-fluorophenol
CID 137038388

Frequently Asked Questions

What is the IUPAC name of 2-[6-[(5,5-dimethyl-4-azaspiro[2.5]octan-7-yl)oxy]pyridazin-3-yl]-5-(5-fluoro-1H-pyrazol-4-yl)pyridin-3-ol;2-[6-[(5,5-dimethyl-4-azaspiro[2.5]octan-7-yl)oxy]pyridazin-3-yl]-5-(1H-pyrazol-4-yl)pyridin-3-ol;2-[6-[[(3R,4R)-3-fluoro-2,2,6,6-tetramethylpiperidin-4-yl]amino]pyridazin-3-yl]-5-[6-(trideuteriomethoxy)pyrimidin-4-yl]pyridin-3-ol?
The IUPAC name of 2-[6-[(5,5-dimethyl-4-azaspiro[2.5]octan-7-yl)oxy]pyridazin-3-yl]-5-(5-fluoro-1H-pyrazol-4-yl)pyridin-3-ol;2-[6-[(5,5-dimethyl-4-azaspiro[2.5]octan-7-yl)oxy]pyridazin-3-yl]-5-(1H-pyrazol-4-yl)pyridin-3-ol;2-[6-[[(3R,4R)-3-fluoro-2,2,6,6-tetramethylpiperidin-4-yl]amino]pyridazin-3-yl]-5-[6-(trideuteriomethoxy)pyrimidin-4-yl]pyridin-3-ol (CID 165003977) is 2-[6-[(5,5-dimethyl-4-azaspiro[2.5]octan-7-yl)oxy]pyridazin-3-yl]-5-(5-fluoro-1H-pyrazol-4-yl)pyridin-3-ol;2-[6-[(5,5-dimethyl-4-azaspiro[2.5]octan-7-yl)oxy]pyridazin-3-yl]-5-(1H-pyrazol-4-yl)pyridin-3-ol;2-[6-[[(3R,4R)-3-fluoro-2,2,6,6-tetramethylpiperidin-4-yl]amino]pyridazin-3-yl]-5-[6-(trideuteriomethoxy)pyrimidin-4-yl]pyridin-3-ol.
What is the SMILES notation for 2-[6-[(5,5-dimethyl-4-azaspiro[2.5]octan-7-yl)oxy]pyridazin-3-yl]-5-(5-fluoro-1H-pyrazol-4-yl)pyridin-3-ol;2-[6-[(5,5-dimethyl-4-azaspiro[2.5]octan-7-yl)oxy]pyridazin-3-yl]-5-(1H-pyrazol-4-yl)pyridin-3-ol;2-[6-[[(3R,4R)-3-fluoro-2,2,6,6-tetramethylpiperidin-4-yl]amino]pyridazin-3-yl]-5-[6-(trideuteriomethoxy)pyrimidin-4-yl]pyridin-3-ol?
The canonical SMILES for 2-[6-[(5,5-dimethyl-4-azaspiro[2.5]octan-7-yl)oxy]pyridazin-3-yl]-5-(5-fluoro-1H-pyrazol-4-yl)pyridin-3-ol;2-[6-[(5,5-dimethyl-4-azaspiro[2.5]octan-7-yl)oxy]pyridazin-3-yl]-5-(1H-pyrazol-4-yl)pyridin-3-ol;2-[6-[[(3R,4R)-3-fluoro-2,2,6,6-tetramethylpiperidin-4-yl]amino]pyridazin-3-yl]-5-[6-(trideuteriomethoxy)pyrimidin-4-yl]pyridin-3-ol is CC1(C)CC(Oc2ccc(-c3ncc(-c4cn[nH]c4)cc3O)nn2)CC2(CC2)N1.CC1(C)CC(Oc2ccc(-c3ncc(-c4cn[nH]c4F)cc3O)nn2)CC2(CC2)N1.[2H]C([2H])([2H])Oc1cc(-c2cnc(-c3ccc(N[C@@H]4CC(C)(C)NC(C)(C)[C@@H]4F)nn3)c(O)c2)ncn1.
What is the InChIKey of 2-[6-[(5,5-dimethyl-4-azaspiro[2.5]octan-7-yl)oxy]pyridazin-3-yl]-5-(5-fluoro-1H-pyrazol-4-yl)pyridin-3-ol;2-[6-[(5,5-dimethyl-4-azaspiro[2.5]octan-7-yl)oxy]pyridazin-3-yl]-5-(1H-pyrazol-4-yl)pyridin-3-ol;2-[6-[[(3R,4R)-3-fluoro-2,2,6,6-tetramethylpiperidin-4-yl]amino]pyridazin-3-yl]-5-[6-(trideuteriomethoxy)pyrimidin-4-yl]pyridin-3-ol?
The InChIKey is IRKIRALWLJWBHU-FZABGYBDSA-N. The full InChI is InChI=1S/C23H28FN7O2.C21H23FN6O2.C21H24N6O2/c1-22(2)10-16(21(24)23(3,4)31-22)28-18-7-6-14(29-30-18)20-17(32)8-13(11-25-20)15-9-19(33-5)27-12-26-15;1-20(2)8-13(9-21(28-20)5-6-21)30-17-4-3-15(25-26-17)18-16(29)7-12(10-23-18)14-11-24-27-19(14)22;1-20(2)8-15(9-21(27-20)5-6-21)29-18-4-3-16(25-26-18)19-17(28)7-13(10-22-19)14-11-23-24-12-14/h6-9,11-12,16,21,31-32H,10H2,1-5H3,(H,28,30);3-4,7,10-11,13,28-29H,5-6,8-9H2,1-2H3,(H,24,27);3-4,7,10-12,15,27-28H,5-6,8-9H2,1-2H3,(H,23,24)/t16-,21-;;/m1../s1/i5D3;;.
What are the key properties of 2-[6-[(5,5-dimethyl-4-azaspiro[2.5]octan-7-yl)oxy]pyridazin-3-yl]-5-(5-fluoro-1H-pyrazol-4-yl)pyridin-3-ol;2-[6-[(5,5-dimethyl-4-azaspiro[2.5]octan-7-yl)oxy]pyridazin-3-yl]-5-(1H-pyrazol-4-yl)pyridin-3-ol;2-[6-[[(3R,4R)-3-fluoro-2,2,6,6-tetramethylpiperidin-4-yl]amino]pyridazin-3-yl]-5-[6-(trideuteriomethoxy)pyrimidin-4-yl]pyridin-3-ol?
2-[6-[(5,5-dimethyl-4-azaspiro[2.5]octan-7-yl)oxy]pyridazin-3-yl]-5-(5-fluoro-1H-pyrazol-4-yl)pyridin-3-ol;2-[6-[(5,5-dimethyl-4-azaspiro[2.5]octan-7-yl)oxy]pyridazin-3-yl]-5-(1H-pyrazol-4-yl)pyridin-3-ol;2-[6-[[(3R,4R)-3-fluoro-2,2,6,6-tetramethylpiperidin-4-yl]amino]pyridazin-3-yl]-5-[6-(trideuteriomethoxy)pyrimidin-4-yl]pyridin-3-ol has a molecular weight of 1259.46 g/mol, XLogP of 9.67, 14 rotatable bonds, 9 hydrogen bond donors, and 23 hydrogen bond acceptors.
Where does this data come from?
All data for 2-[6-[(5,5-dimethyl-4-azaspiro[2.5]octan-7-yl)oxy]pyridazin-3-yl]-5-(5-fluoro-1H-pyrazol-4-yl)pyridin-3-ol;2-[6-[(5,5-dimethyl-4-azaspiro[2.5]octan-7-yl)oxy]pyridazin-3-yl]-5-(1H-pyrazol-4-yl)pyridin-3-ol;2-[6-[[(3R,4R)-3-fluoro-2,2,6,6-tetramethylpiperidin-4-yl]amino]pyridazin-3-yl]-5-[6-(trideuteriomethoxy)pyrimidin-4-yl]pyridin-3-ol is sourced from PubChem (CID 165003977), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).