N-[3,3-difluoro-1-(1-propan-2-ylazetidin-3-yl)piperidin-4-yl]-2-methylpropanamide;N-[1-(3,3-difluoro-1-propan-2-ylpiperidin-4-yl)piperidin-4-yl]-2-methylpropanamide;N-[3,3-difluoro-1-(1-propan-2-ylpiperidin-4-yl)piperidin-4-yl]-2-methylpropanamide;N-[4,4-difluoro-1-(1-propan-2-ylpiperidin-4-yl)pyrrolidin-3-yl]-2-methylpropanamide;2-methyl-N-[1-(1-propan-2-ylazetidin-3-yl)piperidin-4-yl]propanamide;2-methyl-N-[1-(1-propan-2-ylpiperidin-4-yl)pyrrolidin-3-yl]propanamide

C96H178F8N18O6 — CID 165013483

About N-[3,3-difluoro-1-(1-propan-2-ylazetidin-3-yl)piperidin-4-yl]-2-methylpropanamide;N-[1-(3,3-difluoro-1-propan-2-ylpiperidin-4-yl)piperidin-4-yl]-2-methylpropanamide;N-[3,3-difluoro-1-(1-propan-2-ylpiperidin-4-yl)piperidin-4-yl]-2-methylpropanamide;N-[4,4-difluoro-1-(1-propan-2-ylpiperidin-4-yl)pyrrolidin-3-yl]-2-methylpropanamide;2-methyl-N-[1-(1-propan-2-ylazetidin-3-yl)piperidin-4-yl]propanamide;2-methyl-N-[1-(1-propan-2-ylpiperidin-4-yl)pyrrolidin-3-yl]propanamide

N-[3,3-difluoro-1-(1-propan-2-ylazetidin-3-yl)piperidin-4-yl]-2-methylpropanamide;N-[1-(3,3-difluoro-1-propan-2-ylpiperidin-4-yl)piperidin-4-yl]-2-methylpropanamide;N-[3,3-difluoro-1-(1-propan-2-ylpiperidin-4-yl)piperidin-4-yl]-2-methylpropanamide;N-[4,4-difluoro-1-(1-propan-2-ylpiperidin-4-yl)pyrrolidin-3-yl]-2-methylpropanamide;2-methyl-N-[1-(1-propan-2-ylazetidin-3-yl)piperidin-4-yl]propanamide;2-methyl-N-[1-(1-propan-2-ylpiperidin-4-yl)pyrrolidin-3-yl]propanamide (PubChem CID 165013483) has the molecular formula C96H178F8N18O6 and a molecular weight of 1832.58 g/mol. Its IUPAC name is N-[3,3-difluoro-1-(1-propan-2-ylazetidin-3-yl)piperidin-4-yl]-2-methylpropanamide;N-[1-(3,3-difluoro-1-propan-2-ylpiperidin-4-yl)piperidin-4-yl]-2-methylpropanamide;N-[3,3-difluoro-1-(1-propan-2-ylpiperidin-4-yl)piperidin-4-yl]-2-methylpropanamide;N-[4,4-difluoro-1-(1-propan-2-ylpiperidin-4-yl)pyrrolidin-3-yl]-2-methylpropanamide;2-methyl-N-[1-(1-propan-2-ylazetidin-3-yl)piperidin-4-yl]propanamide;2-methyl-N-[1-(1-propan-2-ylpiperidin-4-yl)pyrrolidin-3-yl]propanamide.

Molecular Properties

• Compound Name: N-[3,3-difluoro-1-(1-propan-2-ylazetidin-3-yl)piperidin-4-yl]-2-methylpropanamide;N-[1-(3,3-difluoro-1-propan-2-ylpiperidin-4-yl)piperidin-4-yl]-2-methylpropanamide;N-[3,3-difluoro-1-(1-propan-2-ylpiperidin-4-yl)piperidin-4-yl]-2-methylpropanamide;N-[4,4-difluoro-1-(1-propan-2-ylpiperidin-4-yl)pyrrolidin-3-yl]-2-methylpropanamide;2-methyl-N-[1-(1-propan-2-ylazetidin-3-yl)piperidin-4-yl]propanamide;2-methyl-N-[1-(1-propan-2-ylpiperidin-4-yl)pyrrolidin-3-yl]propanamide
• PubChem CID: 165013483
• Molecular Formula: C96H178F8N18O6
• Molecular Weight: 1832.58 g/mol
• Exact Mass: 1831.40
• IUPAC Name: N-[3,3-difluoro-1-(1-propan-2-ylazetidin-3-yl)piperidin-4-yl]-2-methylpropanamide;N-[1-(3,3-difluoro-1-propan-2-ylpiperidin-4-yl)piperidin-4-yl]-2-methylpropanamide;N-[3,3-difluoro-1-(1-propan-2-ylpiperidin-4-yl)piperidin-4-yl]-2-methylpropanamide;N-[4,4-difluoro-1-(1-propan-2-ylpiperidin-4-yl)pyrrolidin-3-yl]-2-methylpropanamide;2-methyl-N-[1-(1-propan-2-ylazetidin-3-yl)piperidin-4-yl]propanamide;2-methyl-N-[1-(1-propan-2-ylpiperidin-4-yl)pyrrolidin-3-yl]propanamide
• SMILES: CC(C)C(=O)NC1CCN(C2CCN(C(C)C)CC2(F)F)CC1.CC(C)C(=O)NC1CCN(C2CCN(C(C)C)CC2)C1.CC(C)C(=O)NC1CCN(C2CCN(C(C)C)CC2)CC1(F)F.CC(C)C(=O)NC1CCN(C2CN(C(C)C)C2)CC1.CC(C)C(=O)NC1CCN(C2CN(C(C)C)C2)CC1(F)F.CC(C)C(=O)NC1CN(C2CCN(C(C)C)CC2)CC1(F)F
• InChI: InChI=1S/2C17H31F2N3O.C16H29F2N3O.C16H31N3O.C15H27F2N3O.C15H29N3O/c1-12(2)16(23)20-15-7-10-22(11-17(15,18)19)14-5-8-21(9-6-14)13(3)4;1-12(2)16(23)20-14-5-8-21(9-6-14)15-7-10-22(13(3)4)11-17(15,18)19;1-11(2)15(22)19-14-9-21(10-16(14,17)18)13-5-7-20(8-6-13)12(3)4;1-12(2)16(20)17-14-5-8-19(11-14)15-6-9-18(10-7-15)13(3)4;1-10(2)14(21)18-13-5-6-19(9-15(13,16)17)12-7-20(8-12)11(3)4;1-11(2)15(19)16-13-5-7-17(8-6-13)14-9-18(10-14)12(3)4/h2*12-15H,5-11H2,1-4H3,(H,20,23);11-14H,5-10H2,1-4H3,(H,19,22);12-15H,5-11H2,1-4H3,(H,17,20);10-13H,5-9H2,1-4H3,(H,18,21);11-14H,5-10H2,1-4H3,(H,16,19)
• InChIKey: KAZILYVYDFCJAO-UHFFFAOYSA-N
• XLogP: 11.22
• TPSA: 213.48 Ų
• H-Bond Donors: 6
• H-Bond Acceptors: 18
• Rotatable Bonds: 24
• Heavy Atoms: 128
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	1832.58
LogP ≤ 5	11.22
H-Bond Donors ≤ 5	6
H-Bond Acceptors ≤ 10	18

Frequently Asked Questions

What is the IUPAC name of N-[3,3-difluoro-1-(1-propan-2-ylazetidin-3-yl)piperidin-4-yl]-2-methylpropanamide;N-[1-(3,3-difluoro-1-propan-2-ylpiperidin-4-yl)piperidin-4-yl]-2-methylpropanamide;N-[3,3-difluoro-1-(1-propan-2-ylpiperidin-4-yl)piperidin-4-yl]-2-methylpropanamide;N-[4,4-difluoro-1-(1-propan-2-ylpiperidin-4-yl)pyrrolidin-3-yl]-2-methylpropanamide;2-methyl-N-[1-(1-propan-2-ylazetidin-3-yl)piperidin-4-yl]propanamide;2-methyl-N-[1-(1-propan-2-ylpiperidin-4-yl)pyrrolidin-3-yl]propanamide?

The IUPAC name of N-[3,3-difluoro-1-(1-propan-2-ylazetidin-3-yl)piperidin-4-yl]-2-methylpropanamide;N-[1-(3,3-difluoro-1-propan-2-ylpiperidin-4-yl)piperidin-4-yl]-2-methylpropanamide;N-[3,3-difluoro-1-(1-propan-2-ylpiperidin-4-yl)piperidin-4-yl]-2-methylpropanamide;N-[4,4-difluoro-1-(1-propan-2-ylpiperidin-4-yl)pyrrolidin-3-yl]-2-methylpropanamide;2-methyl-N-[1-(1-propan-2-ylazetidin-3-yl)piperidin-4-yl]propanamide;2-methyl-N-[1-(1-propan-2-ylpiperidin-4-yl)pyrrolidin-3-yl]propanamide (CID 165013483) is N-[3,3-difluoro-1-(1-propan-2-ylazetidin-3-yl)piperidin-4-yl]-2-methylpropanamide;N-[1-(3,3-difluoro-1-propan-2-ylpiperidin-4-yl)piperidin-4-yl]-2-methylpropanamide;N-[3,3-difluoro-1-(1-propan-2-ylpiperidin-4-yl)piperidin-4-yl]-2-methylpropanamide;N-[4,4-difluoro-1-(1-propan-2-ylpiperidin-4-yl)pyrrolidin-3-yl]-2-methylpropanamide;2-methyl-N-[1-(1-propan-2-ylazetidin-3-yl)piperidin-4-yl]propanamide;2-methyl-N-[1-(1-propan-2-ylpiperidin-4-yl)pyrrolidin-3-yl]propanamide.

What is the SMILES notation for N-[3,3-difluoro-1-(1-propan-2-ylazetidin-3-yl)piperidin-4-yl]-2-methylpropanamide;N-[1-(3,3-difluoro-1-propan-2-ylpiperidin-4-yl)piperidin-4-yl]-2-methylpropanamide;N-[3,3-difluoro-1-(1-propan-2-ylpiperidin-4-yl)piperidin-4-yl]-2-methylpropanamide;N-[4,4-difluoro-1-(1-propan-2-ylpiperidin-4-yl)pyrrolidin-3-yl]-2-methylpropanamide;2-methyl-N-[1-(1-propan-2-ylazetidin-3-yl)piperidin-4-yl]propanamide;2-methyl-N-[1-(1-propan-2-ylpiperidin-4-yl)pyrrolidin-3-yl]propanamide?

The canonical SMILES for N-[3,3-difluoro-1-(1-propan-2-ylazetidin-3-yl)piperidin-4-yl]-2-methylpropanamide;N-[1-(3,3-difluoro-1-propan-2-ylpiperidin-4-yl)piperidin-4-yl]-2-methylpropanamide;N-[3,3-difluoro-1-(1-propan-2-ylpiperidin-4-yl)piperidin-4-yl]-2-methylpropanamide;N-[4,4-difluoro-1-(1-propan-2-ylpiperidin-4-yl)pyrrolidin-3-yl]-2-methylpropanamide;2-methyl-N-[1-(1-propan-2-ylazetidin-3-yl)piperidin-4-yl]propanamide;2-methyl-N-[1-(1-propan-2-ylpiperidin-4-yl)pyrrolidin-3-yl]propanamide is CC(C)C(=O)NC1CCN(C2CCN(C(C)C)CC2(F)F)CC1.CC(C)C(=O)NC1CCN(C2CCN(C(C)C)CC2)C1.CC(C)C(=O)NC1CCN(C2CCN(C(C)C)CC2)CC1(F)F.CC(C)C(=O)NC1CCN(C2CN(C(C)C)C2)CC1.CC(C)C(=O)NC1CCN(C2CN(C(C)C)C2)CC1(F)F.CC(C)C(=O)NC1CN(C2CCN(C(C)C)CC2)CC1(F)F.

What is the InChIKey of N-[3,3-difluoro-1-(1-propan-2-ylazetidin-3-yl)piperidin-4-yl]-2-methylpropanamide;N-[1-(3,3-difluoro-1-propan-2-ylpiperidin-4-yl)piperidin-4-yl]-2-methylpropanamide;N-[3,3-difluoro-1-(1-propan-2-ylpiperidin-4-yl)piperidin-4-yl]-2-methylpropanamide;N-[4,4-difluoro-1-(1-propan-2-ylpiperidin-4-yl)pyrrolidin-3-yl]-2-methylpropanamide;2-methyl-N-[1-(1-propan-2-ylazetidin-3-yl)piperidin-4-yl]propanamide;2-methyl-N-[1-(1-propan-2-ylpiperidin-4-yl)pyrrolidin-3-yl]propanamide?

The InChIKey is KAZILYVYDFCJAO-UHFFFAOYSA-N. The full InChI is InChI=1S/2C17H31F2N3O.C16H29F2N3O.C16H31N3O.C15H27F2N3O.C15H29N3O/c1-12(2)16(23)20-15-7-10-22(11-17(15,18)19)14-5-8-21(9-6-14)13(3)4;1-12(2)16(23)20-14-5-8-21(9-6-14)15-7-10-22(13(3)4)11-17(15,18)19;1-11(2)15(22)19-14-9-21(10-16(14,17)18)13-5-7-20(8-6-13)12(3)4;1-12(2)16(20)17-14-5-8-19(11-14)15-6-9-18(10-7-15)13(3)4;1-10(2)14(21)18-13-5-6-19(9-15(13,16)17)12-7-20(8-12)11(3)4;1-11(2)15(19)16-13-5-7-17(8-6-13)14-9-18(10-14)12(3)4/h2*12-15H,5-11H2,1-4H3,(H,20,23);11-14H,5-10H2,1-4H3,(H,19,22);12-15H,5-11H2,1-4H3,(H,17,20);10-13H,5-9H2,1-4H3,(H,18,21);11-14H,5-10H2,1-4H3,(H,16,19).

What are the key properties of N-[3,3-difluoro-1-(1-propan-2-ylazetidin-3-yl)piperidin-4-yl]-2-methylpropanamide;N-[1-(3,3-difluoro-1-propan-2-ylpiperidin-4-yl)piperidin-4-yl]-2-methylpropanamide;N-[3,3-difluoro-1-(1-propan-2-ylpiperidin-4-yl)piperidin-4-yl]-2-methylpropanamide;N-[4,4-difluoro-1-(1-propan-2-ylpiperidin-4-yl)pyrrolidin-3-yl]-2-methylpropanamide;2-methyl-N-[1-(1-propan-2-ylazetidin-3-yl)piperidin-4-yl]propanamide;2-methyl-N-[1-(1-propan-2-ylpiperidin-4-yl)pyrrolidin-3-yl]propanamide?

N-[3,3-difluoro-1-(1-propan-2-ylazetidin-3-yl)piperidin-4-yl]-2-methylpropanamide;N-[1-(3,3-difluoro-1-propan-2-ylpiperidin-4-yl)piperidin-4-yl]-2-methylpropanamide;N-[3,3-difluoro-1-(1-propan-2-ylpiperidin-4-yl)piperidin-4-yl]-2-methylpropanamide;N-[4,4-difluoro-1-(1-propan-2-ylpiperidin-4-yl)pyrrolidin-3-yl]-2-methylpropanamide;2-methyl-N-[1-(1-propan-2-ylazetidin-3-yl)piperidin-4-yl]propanamide;2-methyl-N-[1-(1-propan-2-ylpiperidin-4-yl)pyrrolidin-3-yl]propanamide has a molecular weight of 1832.58 g/mol, XLogP of 11.22, 24 rotatable bonds, 6 hydrogen bond donors, and 18 hydrogen bond acceptors.

Where does this data come from?

All data for N-[3,3-difluoro-1-(1-propan-2-ylazetidin-3-yl)piperidin-4-yl]-2-methylpropanamide;N-[1-(3,3-difluoro-1-propan-2-ylpiperidin-4-yl)piperidin-4-yl]-2-methylpropanamide;N-[3,3-difluoro-1-(1-propan-2-ylpiperidin-4-yl)piperidin-4-yl]-2-methylpropanamide;N-[4,4-difluoro-1-(1-propan-2-ylpiperidin-4-yl)pyrrolidin-3-yl]-2-methylpropanamide;2-methyl-N-[1-(1-propan-2-ylazetidin-3-yl)piperidin-4-yl]propanamide;2-methyl-N-[1-(1-propan-2-ylpiperidin-4-yl)pyrrolidin-3-yl]propanamide is sourced from PubChem (CID 165013483), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).