N-[(R)-cyclopropyl-(5-fluoro-2-methoxyphenyl)methyl]-3-(5,5-dimethyl-2H-1,2,4-oxadiazol-3-yl)pyrazolo[1,5-a]pyrimidin-5-amine;3-(5,5-dimethyl-2H-1,2,4-oxadiazol-3-yl)-N-[(1R)-1-(6-fluoroisoquinolin-8-yl)ethyl]pyrazolo[1,5-a]pyrimidin-5-amine;3-(5,5-dimethyl-2H-1,2,4-oxadiazol-3-yl)-N-[(1R)-1-(7-fluoroisoquinolin-5-yl)ethyl]pyrazolo[1,5-a]pyrimidin-5-amine;3-(5,5-dimethyl-2H-1,2,4-oxadiazol-3-yl)-N-[(1R)-1-(3-fluoro-8-methoxynaphthalen-1-yl)ethyl]pyrazolo[1,5-a]pyrimidin-5-amine;2-[(1R)-1-[[3-(5,5-dimethyl-2H-1,2,4-oxadiazol-3-yl)pyrazolo[1,5-a]pyrimidin-5-yl]amino]ethyl]-4-fluoro-N,N-dimethylbenzamide;3-(5,5-dimethyl-2H-1,2,4-oxadiazol-3-yl)-N-[(1S)-2,2,2-trifluoro-1-(5-fluoro-2-methoxyphenyl)ethyl]pyrazolo[1,5-a]pyrimidin-5-amine

C126H128F9N39O10 — CID 165043591

About N-[(R)-cyclopropyl-(5-fluoro-2-methoxyphenyl)methyl]-3-(5,5-dimethyl-2H-1,2,4-oxadiazol-3-yl)pyrazolo[1,5-a]pyrimidin-5-amine;3-(5,5-dimethyl-2H-1,2,4-oxadiazol-3-yl)-N-[(1R)-1-(6-fluoroisoquinolin-8-yl)ethyl]pyrazolo[1,5-a]pyrimidin-5-amine;3-(5,5-dimethyl-2H-1,2,4-oxadiazol-3-yl)-N-[(1R)-1-(7-fluoroisoquinolin-5-yl)ethyl]pyrazolo[1,5-a]pyrimidin-5-amine;3-(5,5-dimethyl-2H-1,2,4-oxadiazol-3-yl)-N-[(1R)-1-(3-fluoro-8-methoxynaphthalen-1-yl)ethyl]pyrazolo[1,5-a]pyrimidin-5-amine;2-[(1R)-1-[[3-(5,5-dimethyl-2H-1,2,4-oxadiazol-3-yl)pyrazolo[1,5-a]pyrimidin-5-yl]amino]ethyl]-4-fluoro-N,N-dimethylbenzamide;3-(5,5-dimethyl-2H-1,2,4-oxadiazol-3-yl)-N-[(1S)-2,2,2-trifluoro-1-(5-fluoro-2-methoxyphenyl)ethyl]pyrazolo[1,5-a]pyrimidin-5-amine

N-[(R)-cyclopropyl-(5-fluoro-2-methoxyphenyl)methyl]-3-(5,5-dimethyl-2H-1,2,4-oxadiazol-3-yl)pyrazolo[1,5-a]pyrimidin-5-amine;3-(5,5-dimethyl-2H-1,2,4-oxadiazol-3-yl)-N-[(1R)-1-(6-fluoroisoquinolin-8-yl)ethyl]pyrazolo[1,5-a]pyrimidin-5-amine;3-(5,5-dimethyl-2H-1,2,4-oxadiazol-3-yl)-N-[(1R)-1-(7-fluoroisoquinolin-5-yl)ethyl]pyrazolo[1,5-a]pyrimidin-5-amine;3-(5,5-dimethyl-2H-1,2,4-oxadiazol-3-yl)-N-[(1R)-1-(3-fluoro-8-methoxynaphthalen-1-yl)ethyl]pyrazolo[1,5-a]pyrimidin-5-amine;2-[(1R)-1-[[3-(5,5-dimethyl-2H-1,2,4-oxadiazol-3-yl)pyrazolo[1,5-a]pyrimidin-5-yl]amino]ethyl]-4-fluoro-N,N-dimethylbenzamide;3-(5,5-dimethyl-2H-1,2,4-oxadiazol-3-yl)-N-[(1S)-2,2,2-trifluoro-1-(5-fluoro-2-methoxyphenyl)ethyl]pyrazolo[1,5-a]pyrimidin-5-amine (PubChem CID 165043591) has the molecular formula C126H128F9N39O10 and a molecular weight of 2519.65 g/mol. Its IUPAC name is N-[(R)-cyclopropyl-(5-fluoro-2-methoxyphenyl)methyl]-3-(5,5-dimethyl-2H-1,2,4-oxadiazol-3-yl)pyrazolo[1,5-a]pyrimidin-5-amine;3-(5,5-dimethyl-2H-1,2,4-oxadiazol-3-yl)-N-[(1R)-1-(6-fluoroisoquinolin-8-yl)ethyl]pyrazolo[1,5-a]pyrimidin-5-amine;3-(5,5-dimethyl-2H-1,2,4-oxadiazol-3-yl)-N-[(1R)-1-(7-fluoroisoquinolin-5-yl)ethyl]pyrazolo[1,5-a]pyrimidin-5-amine;3-(5,5-dimethyl-2H-1,2,4-oxadiazol-3-yl)-N-[(1R)-1-(3-fluoro-8-methoxynaphthalen-1-yl)ethyl]pyrazolo[1,5-a]pyrimidin-5-amine;2-[(1R)-1-[[3-(5,5-dimethyl-2H-1,2,4-oxadiazol-3-yl)pyrazolo[1,5-a]pyrimidin-5-yl]amino]ethyl]-4-fluoro-N,N-dimethylbenzamide;3-(5,5-dimethyl-2H-1,2,4-oxadiazol-3-yl)-N-[(1S)-2,2,2-trifluoro-1-(5-fluoro-2-methoxyphenyl)ethyl]pyrazolo[1,5-a]pyrimidin-5-amine.

Molecular Properties

• Compound Name: N-[(R)-cyclopropyl-(5-fluoro-2-methoxyphenyl)methyl]-3-(5,5-dimethyl-2H-1,2,4-oxadiazol-3-yl)pyrazolo[1,5-a]pyrimidin-5-amine;3-(5,5-dimethyl-2H-1,2,4-oxadiazol-3-yl)-N-[(1R)-1-(6-fluoroisoquinolin-8-yl)ethyl]pyrazolo[1,5-a]pyrimidin-5-amine;3-(5,5-dimethyl-2H-1,2,4-oxadiazol-3-yl)-N-[(1R)-1-(7-fluoroisoquinolin-5-yl)ethyl]pyrazolo[1,5-a]pyrimidin-5-amine;3-(5,5-dimethyl-2H-1,2,4-oxadiazol-3-yl)-N-[(1R)-1-(3-fluoro-8-methoxynaphthalen-1-yl)ethyl]pyrazolo[1,5-a]pyrimidin-5-amine;2-[(1R)-1-[[3-(5,5-dimethyl-2H-1,2,4-oxadiazol-3-yl)pyrazolo[1,5-a]pyrimidin-5-yl]amino]ethyl]-4-fluoro-N,N-dimethylbenzamide;3-(5,5-dimethyl-2H-1,2,4-oxadiazol-3-yl)-N-[(1S)-2,2,2-trifluoro-1-(5-fluoro-2-methoxyphenyl)ethyl]pyrazolo[1,5-a]pyrimidin-5-amine
• PubChem CID: 165043591
• Molecular Formula: C126H128F9N39O10
• Molecular Weight: 2519.65 g/mol
• Exact Mass: 2518.06
• IUPAC Name: N-[(R)-cyclopropyl-(5-fluoro-2-methoxyphenyl)methyl]-3-(5,5-dimethyl-2H-1,2,4-oxadiazol-3-yl)pyrazolo[1,5-a]pyrimidin-5-amine;3-(5,5-dimethyl-2H-1,2,4-oxadiazol-3-yl)-N-[(1R)-1-(6-fluoroisoquinolin-8-yl)ethyl]pyrazolo[1,5-a]pyrimidin-5-amine;3-(5,5-dimethyl-2H-1,2,4-oxadiazol-3-yl)-N-[(1R)-1-(7-fluoroisoquinolin-5-yl)ethyl]pyrazolo[1,5-a]pyrimidin-5-amine;3-(5,5-dimethyl-2H-1,2,4-oxadiazol-3-yl)-N-[(1R)-1-(3-fluoro-8-methoxynaphthalen-1-yl)ethyl]pyrazolo[1,5-a]pyrimidin-5-amine;2-[(1R)-1-[[3-(5,5-dimethyl-2H-1,2,4-oxadiazol-3-yl)pyrazolo[1,5-a]pyrimidin-5-yl]amino]ethyl]-4-fluoro-N,N-dimethylbenzamide;3-(5,5-dimethyl-2H-1,2,4-oxadiazol-3-yl)-N-[(1S)-2,2,2-trifluoro-1-(5-fluoro-2-methoxyphenyl)ethyl]pyrazolo[1,5-a]pyrimidin-5-amine
• SMILES: COc1ccc(F)cc1[C@H](Nc1ccn2ncc(C3=NC(C)(C)ON3)c2n1)C(F)(F)F.COc1ccc(F)cc1[C@H](Nc1ccn2ncc(C3=NC(C)(C)ON3)c2n1)C1CC1.COc1cccc2cc(F)cc([C@@H](C)Nc3ccn4ncc(C5=NC(C)(C)ON5)c4n3)c12.C[C@@H](Nc1ccn2ncc(C3=NC(C)(C)ON3)c2n1)c1cc(F)cc2ccncc12.C[C@@H](Nc1ccn2ncc(C3=NC(C)(C)ON3)c2n1)c1cc(F)cc2cnccc12.C[C@@H](Nc1ccn2ncc(C3=NC(C)(C)ON3)c2n1)c1cc(F)ccc1C(=O)N(C)C
• InChI: InChI=1S/C23H23FN6O2.C21H24FN7O2.2C21H20FN7O.C21H23FN6O2.C19H18F4N6O2/c1-13(16-11-15(24)10-14-6-5-7-18(31-4)20(14)16)26-19-8-9-30-22(27-19)17(12-25-30)21-28-23(2,3)32-29-21;1-12(15-10-13(22)6-7-14(15)20(30)28(4)5)24-17-8-9-29-19(25-17)16(11-23-29)18-26-21(2,3)31-27-18;1-12(16-9-14(22)8-13-10-23-6-4-15(13)16)25-18-5-7-29-20(26-18)17(11-24-29)19-27-21(2,3)30-28-19;1-12(15-9-14(22)8-13-4-6-23-10-16(13)15)25-18-5-7-29-20(26-18)17(11-24-29)19-27-21(2,3)30-28-19;1-21(2)26-19(27-30-21)15-11-23-28-9-8-17(25-20(15)28)24-18(12-4-5-12)14-10-13(22)6-7-16(14)29-3;1-18(2)27-16(28-31-18)12-9-24-29-7-6-14(26-17(12)29)25-15(19(21,22)23)11-8-10(20)4-5-13(11)30-3/h5-13H,1-4H3,(H,26,27)(H,28,29);6-12H,1-5H3,(H,24,25)(H,26,27);2*4-12H,1-3H3,(H,25,26)(H,27,28);6-12,18H,4-5H2,1-3H3,(H,24,25)(H,26,27);4-9,15H,1-3H3,(H,25,26)(H,27,28)/t13-;3*12-;18-;15-/m111110/s1
• InChIKey: ONKKSVWQEMQEBY-ZWKABDSHSA-N
• XLogP: 21.26
• TPSA: 528.82 Ų
• H-Bond Donors: 12
• H-Bond Acceptors: 48
• Rotatable Bonds: 29
• Heavy Atoms: 184
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2519.65
LogP ≤ 5	21.26
H-Bond Donors ≤ 5	12
H-Bond Acceptors ≤ 10	48

Frequently Asked Questions

What is the IUPAC name of N-[(R)-cyclopropyl-(5-fluoro-2-methoxyphenyl)methyl]-3-(5,5-dimethyl-2H-1,2,4-oxadiazol-3-yl)pyrazolo[1,5-a]pyrimidin-5-amine;3-(5,5-dimethyl-2H-1,2,4-oxadiazol-3-yl)-N-[(1R)-1-(6-fluoroisoquinolin-8-yl)ethyl]pyrazolo[1,5-a]pyrimidin-5-amine;3-(5,5-dimethyl-2H-1,2,4-oxadiazol-3-yl)-N-[(1R)-1-(7-fluoroisoquinolin-5-yl)ethyl]pyrazolo[1,5-a]pyrimidin-5-amine;3-(5,5-dimethyl-2H-1,2,4-oxadiazol-3-yl)-N-[(1R)-1-(3-fluoro-8-methoxynaphthalen-1-yl)ethyl]pyrazolo[1,5-a]pyrimidin-5-amine;2-[(1R)-1-[[3-(5,5-dimethyl-2H-1,2,4-oxadiazol-3-yl)pyrazolo[1,5-a]pyrimidin-5-yl]amino]ethyl]-4-fluoro-N,N-dimethylbenzamide;3-(5,5-dimethyl-2H-1,2,4-oxadiazol-3-yl)-N-[(1S)-2,2,2-trifluoro-1-(5-fluoro-2-methoxyphenyl)ethyl]pyrazolo[1,5-a]pyrimidin-5-amine?

The IUPAC name of N-[(R)-cyclopropyl-(5-fluoro-2-methoxyphenyl)methyl]-3-(5,5-dimethyl-2H-1,2,4-oxadiazol-3-yl)pyrazolo[1,5-a]pyrimidin-5-amine;3-(5,5-dimethyl-2H-1,2,4-oxadiazol-3-yl)-N-[(1R)-1-(6-fluoroisoquinolin-8-yl)ethyl]pyrazolo[1,5-a]pyrimidin-5-amine;3-(5,5-dimethyl-2H-1,2,4-oxadiazol-3-yl)-N-[(1R)-1-(7-fluoroisoquinolin-5-yl)ethyl]pyrazolo[1,5-a]pyrimidin-5-amine;3-(5,5-dimethyl-2H-1,2,4-oxadiazol-3-yl)-N-[(1R)-1-(3-fluoro-8-methoxynaphthalen-1-yl)ethyl]pyrazolo[1,5-a]pyrimidin-5-amine;2-[(1R)-1-[[3-(5,5-dimethyl-2H-1,2,4-oxadiazol-3-yl)pyrazolo[1,5-a]pyrimidin-5-yl]amino]ethyl]-4-fluoro-N,N-dimethylbenzamide;3-(5,5-dimethyl-2H-1,2,4-oxadiazol-3-yl)-N-[(1S)-2,2,2-trifluoro-1-(5-fluoro-2-methoxyphenyl)ethyl]pyrazolo[1,5-a]pyrimidin-5-amine (CID 165043591) is N-[(R)-cyclopropyl-(5-fluoro-2-methoxyphenyl)methyl]-3-(5,5-dimethyl-2H-1,2,4-oxadiazol-3-yl)pyrazolo[1,5-a]pyrimidin-5-amine;3-(5,5-dimethyl-2H-1,2,4-oxadiazol-3-yl)-N-[(1R)-1-(6-fluoroisoquinolin-8-yl)ethyl]pyrazolo[1,5-a]pyrimidin-5-amine;3-(5,5-dimethyl-2H-1,2,4-oxadiazol-3-yl)-N-[(1R)-1-(7-fluoroisoquinolin-5-yl)ethyl]pyrazolo[1,5-a]pyrimidin-5-amine;3-(5,5-dimethyl-2H-1,2,4-oxadiazol-3-yl)-N-[(1R)-1-(3-fluoro-8-methoxynaphthalen-1-yl)ethyl]pyrazolo[1,5-a]pyrimidin-5-amine;2-[(1R)-1-[[3-(5,5-dimethyl-2H-1,2,4-oxadiazol-3-yl)pyrazolo[1,5-a]pyrimidin-5-yl]amino]ethyl]-4-fluoro-N,N-dimethylbenzamide;3-(5,5-dimethyl-2H-1,2,4-oxadiazol-3-yl)-N-[(1S)-2,2,2-trifluoro-1-(5-fluoro-2-methoxyphenyl)ethyl]pyrazolo[1,5-a]pyrimidin-5-amine.

What is the SMILES notation for N-[(R)-cyclopropyl-(5-fluoro-2-methoxyphenyl)methyl]-3-(5,5-dimethyl-2H-1,2,4-oxadiazol-3-yl)pyrazolo[1,5-a]pyrimidin-5-amine;3-(5,5-dimethyl-2H-1,2,4-oxadiazol-3-yl)-N-[(1R)-1-(6-fluoroisoquinolin-8-yl)ethyl]pyrazolo[1,5-a]pyrimidin-5-amine;3-(5,5-dimethyl-2H-1,2,4-oxadiazol-3-yl)-N-[(1R)-1-(7-fluoroisoquinolin-5-yl)ethyl]pyrazolo[1,5-a]pyrimidin-5-amine;3-(5,5-dimethyl-2H-1,2,4-oxadiazol-3-yl)-N-[(1R)-1-(3-fluoro-8-methoxynaphthalen-1-yl)ethyl]pyrazolo[1,5-a]pyrimidin-5-amine;2-[(1R)-1-[[3-(5,5-dimethyl-2H-1,2,4-oxadiazol-3-yl)pyrazolo[1,5-a]pyrimidin-5-yl]amino]ethyl]-4-fluoro-N,N-dimethylbenzamide;3-(5,5-dimethyl-2H-1,2,4-oxadiazol-3-yl)-N-[(1S)-2,2,2-trifluoro-1-(5-fluoro-2-methoxyphenyl)ethyl]pyrazolo[1,5-a]pyrimidin-5-amine?

The canonical SMILES for N-[(R)-cyclopropyl-(5-fluoro-2-methoxyphenyl)methyl]-3-(5,5-dimethyl-2H-1,2,4-oxadiazol-3-yl)pyrazolo[1,5-a]pyrimidin-5-amine;3-(5,5-dimethyl-2H-1,2,4-oxadiazol-3-yl)-N-[(1R)-1-(6-fluoroisoquinolin-8-yl)ethyl]pyrazolo[1,5-a]pyrimidin-5-amine;3-(5,5-dimethyl-2H-1,2,4-oxadiazol-3-yl)-N-[(1R)-1-(7-fluoroisoquinolin-5-yl)ethyl]pyrazolo[1,5-a]pyrimidin-5-amine;3-(5,5-dimethyl-2H-1,2,4-oxadiazol-3-yl)-N-[(1R)-1-(3-fluoro-8-methoxynaphthalen-1-yl)ethyl]pyrazolo[1,5-a]pyrimidin-5-amine;2-[(1R)-1-[[3-(5,5-dimethyl-2H-1,2,4-oxadiazol-3-yl)pyrazolo[1,5-a]pyrimidin-5-yl]amino]ethyl]-4-fluoro-N,N-dimethylbenzamide;3-(5,5-dimethyl-2H-1,2,4-oxadiazol-3-yl)-N-[(1S)-2,2,2-trifluoro-1-(5-fluoro-2-methoxyphenyl)ethyl]pyrazolo[1,5-a]pyrimidin-5-amine is COc1ccc(F)cc1[C@H](Nc1ccn2ncc(C3=NC(C)(C)ON3)c2n1)C(F)(F)F.COc1ccc(F)cc1[C@H](Nc1ccn2ncc(C3=NC(C)(C)ON3)c2n1)C1CC1.COc1cccc2cc(F)cc([C@@H](C)Nc3ccn4ncc(C5=NC(C)(C)ON5)c4n3)c12.C[C@@H](Nc1ccn2ncc(C3=NC(C)(C)ON3)c2n1)c1cc(F)cc2ccncc12.C[C@@H](Nc1ccn2ncc(C3=NC(C)(C)ON3)c2n1)c1cc(F)cc2cnccc12.C[C@@H](Nc1ccn2ncc(C3=NC(C)(C)ON3)c2n1)c1cc(F)ccc1C(=O)N(C)C.

What is the InChIKey of N-[(R)-cyclopropyl-(5-fluoro-2-methoxyphenyl)methyl]-3-(5,5-dimethyl-2H-1,2,4-oxadiazol-3-yl)pyrazolo[1,5-a]pyrimidin-5-amine;3-(5,5-dimethyl-2H-1,2,4-oxadiazol-3-yl)-N-[(1R)-1-(6-fluoroisoquinolin-8-yl)ethyl]pyrazolo[1,5-a]pyrimidin-5-amine;3-(5,5-dimethyl-2H-1,2,4-oxadiazol-3-yl)-N-[(1R)-1-(7-fluoroisoquinolin-5-yl)ethyl]pyrazolo[1,5-a]pyrimidin-5-amine;3-(5,5-dimethyl-2H-1,2,4-oxadiazol-3-yl)-N-[(1R)-1-(3-fluoro-8-methoxynaphthalen-1-yl)ethyl]pyrazolo[1,5-a]pyrimidin-5-amine;2-[(1R)-1-[[3-(5,5-dimethyl-2H-1,2,4-oxadiazol-3-yl)pyrazolo[1,5-a]pyrimidin-5-yl]amino]ethyl]-4-fluoro-N,N-dimethylbenzamide;3-(5,5-dimethyl-2H-1,2,4-oxadiazol-3-yl)-N-[(1S)-2,2,2-trifluoro-1-(5-fluoro-2-methoxyphenyl)ethyl]pyrazolo[1,5-a]pyrimidin-5-amine?

The InChIKey is ONKKSVWQEMQEBY-ZWKABDSHSA-N. The full InChI is InChI=1S/C23H23FN6O2.C21H24FN7O2.2C21H20FN7O.C21H23FN6O2.C19H18F4N6O2/c1-13(16-11-15(24)10-14-6-5-7-18(31-4)20(14)16)26-19-8-9-30-22(27-19)17(12-25-30)21-28-23(2,3)32-29-21;1-12(15-10-13(22)6-7-14(15)20(30)28(4)5)24-17-8-9-29-19(25-17)16(11-23-29)18-26-21(2,3)31-27-18;1-12(16-9-14(22)8-13-10-23-6-4-15(13)16)25-18-5-7-29-20(26-18)17(11-24-29)19-27-21(2,3)30-28-19;1-12(15-9-14(22)8-13-4-6-23-10-16(13)15)25-18-5-7-29-20(26-18)17(11-24-29)19-27-21(2,3)30-28-19;1-21(2)26-19(27-30-21)15-11-23-28-9-8-17(25-20(15)28)24-18(12-4-5-12)14-10-13(22)6-7-16(14)29-3;1-18(2)27-16(28-31-18)12-9-24-29-7-6-14(26-17(12)29)25-15(19(21,22)23)11-8-10(20)4-5-13(11)30-3/h5-13H,1-4H3,(H,26,27)(H,28,29);6-12H,1-5H3,(H,24,25)(H,26,27);2*4-12H,1-3H3,(H,25,26)(H,27,28);6-12,18H,4-5H2,1-3H3,(H,24,25)(H,26,27);4-9,15H,1-3H3,(H,25,26)(H,27,28)/t13-;3*12-;18-;15-/m111110/s1.

What are the key properties of N-[(R)-cyclopropyl-(5-fluoro-2-methoxyphenyl)methyl]-3-(5,5-dimethyl-2H-1,2,4-oxadiazol-3-yl)pyrazolo[1,5-a]pyrimidin-5-amine;3-(5,5-dimethyl-2H-1,2,4-oxadiazol-3-yl)-N-[(1R)-1-(6-fluoroisoquinolin-8-yl)ethyl]pyrazolo[1,5-a]pyrimidin-5-amine;3-(5,5-dimethyl-2H-1,2,4-oxadiazol-3-yl)-N-[(1R)-1-(7-fluoroisoquinolin-5-yl)ethyl]pyrazolo[1,5-a]pyrimidin-5-amine;3-(5,5-dimethyl-2H-1,2,4-oxadiazol-3-yl)-N-[(1R)-1-(3-fluoro-8-methoxynaphthalen-1-yl)ethyl]pyrazolo[1,5-a]pyrimidin-5-amine;2-[(1R)-1-[[3-(5,5-dimethyl-2H-1,2,4-oxadiazol-3-yl)pyrazolo[1,5-a]pyrimidin-5-yl]amino]ethyl]-4-fluoro-N,N-dimethylbenzamide;3-(5,5-dimethyl-2H-1,2,4-oxadiazol-3-yl)-N-[(1S)-2,2,2-trifluoro-1-(5-fluoro-2-methoxyphenyl)ethyl]pyrazolo[1,5-a]pyrimidin-5-amine?

N-[(R)-cyclopropyl-(5-fluoro-2-methoxyphenyl)methyl]-3-(5,5-dimethyl-2H-1,2,4-oxadiazol-3-yl)pyrazolo[1,5-a]pyrimidin-5-amine;3-(5,5-dimethyl-2H-1,2,4-oxadiazol-3-yl)-N-[(1R)-1-(6-fluoroisoquinolin-8-yl)ethyl]pyrazolo[1,5-a]pyrimidin-5-amine;3-(5,5-dimethyl-2H-1,2,4-oxadiazol-3-yl)-N-[(1R)-1-(7-fluoroisoquinolin-5-yl)ethyl]pyrazolo[1,5-a]pyrimidin-5-amine;3-(5,5-dimethyl-2H-1,2,4-oxadiazol-3-yl)-N-[(1R)-1-(3-fluoro-8-methoxynaphthalen-1-yl)ethyl]pyrazolo[1,5-a]pyrimidin-5-amine;2-[(1R)-1-[[3-(5,5-dimethyl-2H-1,2,4-oxadiazol-3-yl)pyrazolo[1,5-a]pyrimidin-5-yl]amino]ethyl]-4-fluoro-N,N-dimethylbenzamide;3-(5,5-dimethyl-2H-1,2,4-oxadiazol-3-yl)-N-[(1S)-2,2,2-trifluoro-1-(5-fluoro-2-methoxyphenyl)ethyl]pyrazolo[1,5-a]pyrimidin-5-amine has a molecular weight of 2519.65 g/mol, XLogP of 21.26, 29 rotatable bonds, 12 hydrogen bond donors, and 48 hydrogen bond acceptors.

Where does this data come from?

All data for N-[(R)-cyclopropyl-(5-fluoro-2-methoxyphenyl)methyl]-3-(5,5-dimethyl-2H-1,2,4-oxadiazol-3-yl)pyrazolo[1,5-a]pyrimidin-5-amine;3-(5,5-dimethyl-2H-1,2,4-oxadiazol-3-yl)-N-[(1R)-1-(6-fluoroisoquinolin-8-yl)ethyl]pyrazolo[1,5-a]pyrimidin-5-amine;3-(5,5-dimethyl-2H-1,2,4-oxadiazol-3-yl)-N-[(1R)-1-(7-fluoroisoquinolin-5-yl)ethyl]pyrazolo[1,5-a]pyrimidin-5-amine;3-(5,5-dimethyl-2H-1,2,4-oxadiazol-3-yl)-N-[(1R)-1-(3-fluoro-8-methoxynaphthalen-1-yl)ethyl]pyrazolo[1,5-a]pyrimidin-5-amine;2-[(1R)-1-[[3-(5,5-dimethyl-2H-1,2,4-oxadiazol-3-yl)pyrazolo[1,5-a]pyrimidin-5-yl]amino]ethyl]-4-fluoro-N,N-dimethylbenzamide;3-(5,5-dimethyl-2H-1,2,4-oxadiazol-3-yl)-N-[(1S)-2,2,2-trifluoro-1-(5-fluoro-2-methoxyphenyl)ethyl]pyrazolo[1,5-a]pyrimidin-5-amine is sourced from PubChem (CID 165043591), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).