(1S)-1'-[8-(2-amino-3-chloro-4-pyridinyl)-7-methylimidazo[1,2-c]pyrimidin-5-yl]spiro[1,3-dihydroindene-2,4'-piperidine]-1-amine;[8-[(2-amino-3-chloro-4-pyridinyl)sulfanyl]-5-[(1S)-1-aminospiro[1,3-dihydroindene-2,4'-piperidine]-1'-yl]-7-methylimidazo[1,2-c]pyrimidin-2-yl]methanol;(1S)-1'-[8-[(2-amino-3-chloro-4-pyridinyl)sulfanyl]-3,7-dimethylimidazo[1,2-c]pyrimidin-5-yl]spiro[1,3-dihydroindene-2,4'-piperidine]-1-amine;(1S)-1'-[8-[(2-chloro-3-pyridinyl)sulfanyl]-7-methylimidazo[1,2-a]pyridin-5-yl]spiro[1,3-dihydroindene-2,4'-piperidine]-1-amine

C103H108Cl4N26OS3 — CID 165060768

About (1S)-1'-[8-(2-amino-3-chloro-4-pyridinyl)-7-methylimidazo[1,2-c]pyrimidin-5-yl]spiro[1,3-dihydroindene-2,4'-piperidine]-1-amine;[8-[(2-amino-3-chloro-4-pyridinyl)sulfanyl]-5-[(1S)-1-aminospiro[1,3-dihydroindene-2,4'-piperidine]-1'-yl]-7-methylimidazo[1,2-c]pyrimidin-2-yl]methanol;(1S)-1'-[8-[(2-amino-3-chloro-4-pyridinyl)sulfanyl]-3,7-dimethylimidazo[1,2-c]pyrimidin-5-yl]spiro[1,3-dihydroindene-2,4'-piperidine]-1-amine;(1S)-1'-[8-[(2-chloro-3-pyridinyl)sulfanyl]-7-methylimidazo[1,2-a]pyridin-5-yl]spiro[1,3-dihydroindene-2,4'-piperidine]-1-amine

(1S)-1'-[8-(2-amino-3-chloro-4-pyridinyl)-7-methylimidazo[1,2-c]pyrimidin-5-yl]spiro[1,3-dihydroindene-2,4'-piperidine]-1-amine;[8-[(2-amino-3-chloro-4-pyridinyl)sulfanyl]-5-[(1S)-1-aminospiro[1,3-dihydroindene-2,4'-piperidine]-1'-yl]-7-methylimidazo[1,2-c]pyrimidin-2-yl]methanol;(1S)-1'-[8-[(2-amino-3-chloro-4-pyridinyl)sulfanyl]-3,7-dimethylimidazo[1,2-c]pyrimidin-5-yl]spiro[1,3-dihydroindene-2,4'-piperidine]-1-amine;(1S)-1'-[8-[(2-chloro-3-pyridinyl)sulfanyl]-7-methylimidazo[1,2-a]pyridin-5-yl]spiro[1,3-dihydroindene-2,4'-piperidine]-1-amine (PubChem CID 165060768) has the molecular formula C103H108Cl4N26OS3 and a molecular weight of 1964.19 g/mol. Its IUPAC name is (1S)-1'-[8-(2-amino-3-chloro-4-pyridinyl)-7-methylimidazo[1,2-c]pyrimidin-5-yl]spiro[1,3-dihydroindene-2,4'-piperidine]-1-amine;[8-[(2-amino-3-chloro-4-pyridinyl)sulfanyl]-5-[(1S)-1-aminospiro[1,3-dihydroindene-2,4'-piperidine]-1'-yl]-7-methylimidazo[1,2-c]pyrimidin-2-yl]methanol;(1S)-1'-[8-[(2-amino-3-chloro-4-pyridinyl)sulfanyl]-3,7-dimethylimidazo[1,2-c]pyrimidin-5-yl]spiro[1,3-dihydroindene-2,4'-piperidine]-1-amine;(1S)-1'-[8-[(2-chloro-3-pyridinyl)sulfanyl]-7-methylimidazo[1,2-a]pyridin-5-yl]spiro[1,3-dihydroindene-2,4'-piperidine]-1-amine.

Molecular Properties

• Compound Name: (1S)-1'-[8-(2-amino-3-chloro-4-pyridinyl)-7-methylimidazo[1,2-c]pyrimidin-5-yl]spiro[1,3-dihydroindene-2,4'-piperidine]-1-amine;[8-[(2-amino-3-chloro-4-pyridinyl)sulfanyl]-5-[(1S)-1-aminospiro[1,3-dihydroindene-2,4'-piperidine]-1'-yl]-7-methylimidazo[1,2-c]pyrimidin-2-yl]methanol;(1S)-1'-[8-[(2-amino-3-chloro-4-pyridinyl)sulfanyl]-3,7-dimethylimidazo[1,2-c]pyrimidin-5-yl]spiro[1,3-dihydroindene-2,4'-piperidine]-1-amine;(1S)-1'-[8-[(2-chloro-3-pyridinyl)sulfanyl]-7-methylimidazo[1,2-a]pyridin-5-yl]spiro[1,3-dihydroindene-2,4'-piperidine]-1-amine
• PubChem CID: 165060768
• Molecular Formula: C103H108Cl4N26OS3
• Molecular Weight: 1964.19 g/mol
• Exact Mass: 1960.71
• IUPAC Name: (1S)-1'-[8-(2-amino-3-chloro-4-pyridinyl)-7-methylimidazo[1,2-c]pyrimidin-5-yl]spiro[1,3-dihydroindene-2,4'-piperidine]-1-amine;[8-[(2-amino-3-chloro-4-pyridinyl)sulfanyl]-5-[(1S)-1-aminospiro[1,3-dihydroindene-2,4'-piperidine]-1'-yl]-7-methylimidazo[1,2-c]pyrimidin-2-yl]methanol;(1S)-1'-[8-[(2-amino-3-chloro-4-pyridinyl)sulfanyl]-3,7-dimethylimidazo[1,2-c]pyrimidin-5-yl]spiro[1,3-dihydroindene-2,4'-piperidine]-1-amine;(1S)-1'-[8-[(2-chloro-3-pyridinyl)sulfanyl]-7-methylimidazo[1,2-a]pyridin-5-yl]spiro[1,3-dihydroindene-2,4'-piperidine]-1-amine
• SMILES: Cc1cc(N2CCC3(CC2)Cc2ccccc2[C@H]3N)n2ccnc2c1Sc1cccnc1Cl.Cc1nc(N2CCC3(CC2)Cc2ccccc2[C@H]3N)n2c(C)cnc2c1Sc1ccnc(N)c1Cl.Cc1nc(N2CCC3(CC2)Cc2ccccc2[C@H]3N)n2cc(CO)nc2c1Sc1ccnc(N)c1Cl.Cc1nc(N2CCC3(CC2)Cc2ccccc2[C@H]3N)n2ccnc2c1-c1ccnc(N)c1Cl
• InChI: InChI=1S/C26H28ClN7OS.C26H28ClN7S.C26H26ClN5S.C25H26ClN7/c1-15-21(36-19-6-9-30-23(29)20(19)27)24-32-17(14-35)13-34(24)25(31-15)33-10-7-26(8-11-33)12-16-4-2-3-5-18(16)22(26)28;1-15-14-31-24-21(35-19-7-10-30-23(29)20(19)27)16(2)32-25(34(15)24)33-11-8-26(9-12-33)13-17-5-3-4-6-18(17)22(26)28;1-17-15-21(32-14-11-30-25(32)22(17)33-20-7-4-10-29-24(20)27)31-12-8-26(9-13-31)16-18-5-2-3-6-19(18)23(26)28;1-15-19(18-6-9-29-22(28)20(18)26)23-30-10-13-33(23)24(31-15)32-11-7-25(8-12-32)14-16-4-2-3-5-17(16)21(25)27/h2-6,9,13,22,35H,7-8,10-12,14,28H2,1H3,(H2,29,30);3-7,10,14,22H,8-9,11-13,28H2,1-2H3,(H2,29,30);2-7,10-11,14-15,23H,8-9,12-13,16,28H2,1H3;2-6,9-10,13,21H,7-8,11-12,14,27H2,1H3,(H2,28,29)/t2*22-;23-;21-/m1111/s1
• InChIKey: RDTXPGWSLYQXQG-BWPILCAZSA-N
• XLogP: 18.99
• TPSA: 374.76 Ų
• H-Bond Donors: 8
• H-Bond Acceptors: 30
• Rotatable Bonds: 12
• Heavy Atoms: 137
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	1964.19
LogP ≤ 5	18.99
H-Bond Donors ≤ 5	8
H-Bond Acceptors ≤ 10	30

Computed Properties (RDKit)

• Structural Alerts: {'alert_name': '2-halo_pyridine', 'substructure': 'N/A'}

Frequently Asked Questions

What is the IUPAC name of (1S)-1'-[8-(2-amino-3-chloro-4-pyridinyl)-7-methylimidazo[1,2-c]pyrimidin-5-yl]spiro[1,3-dihydroindene-2,4'-piperidine]-1-amine;[8-[(2-amino-3-chloro-4-pyridinyl)sulfanyl]-5-[(1S)-1-aminospiro[1,3-dihydroindene-2,4'-piperidine]-1'-yl]-7-methylimidazo[1,2-c]pyrimidin-2-yl]methanol;(1S)-1'-[8-[(2-amino-3-chloro-4-pyridinyl)sulfanyl]-3,7-dimethylimidazo[1,2-c]pyrimidin-5-yl]spiro[1,3-dihydroindene-2,4'-piperidine]-1-amine;(1S)-1'-[8-[(2-chloro-3-pyridinyl)sulfanyl]-7-methylimidazo[1,2-a]pyridin-5-yl]spiro[1,3-dihydroindene-2,4'-piperidine]-1-amine?

The IUPAC name of (1S)-1'-[8-(2-amino-3-chloro-4-pyridinyl)-7-methylimidazo[1,2-c]pyrimidin-5-yl]spiro[1,3-dihydroindene-2,4'-piperidine]-1-amine;[8-[(2-amino-3-chloro-4-pyridinyl)sulfanyl]-5-[(1S)-1-aminospiro[1,3-dihydroindene-2,4'-piperidine]-1'-yl]-7-methylimidazo[1,2-c]pyrimidin-2-yl]methanol;(1S)-1'-[8-[(2-amino-3-chloro-4-pyridinyl)sulfanyl]-3,7-dimethylimidazo[1,2-c]pyrimidin-5-yl]spiro[1,3-dihydroindene-2,4'-piperidine]-1-amine;(1S)-1'-[8-[(2-chloro-3-pyridinyl)sulfanyl]-7-methylimidazo[1,2-a]pyridin-5-yl]spiro[1,3-dihydroindene-2,4'-piperidine]-1-amine (CID 165060768) is (1S)-1'-[8-(2-amino-3-chloro-4-pyridinyl)-7-methylimidazo[1,2-c]pyrimidin-5-yl]spiro[1,3-dihydroindene-2,4'-piperidine]-1-amine;[8-[(2-amino-3-chloro-4-pyridinyl)sulfanyl]-5-[(1S)-1-aminospiro[1,3-dihydroindene-2,4'-piperidine]-1'-yl]-7-methylimidazo[1,2-c]pyrimidin-2-yl]methanol;(1S)-1'-[8-[(2-amino-3-chloro-4-pyridinyl)sulfanyl]-3,7-dimethylimidazo[1,2-c]pyrimidin-5-yl]spiro[1,3-dihydroindene-2,4'-piperidine]-1-amine;(1S)-1'-[8-[(2-chloro-3-pyridinyl)sulfanyl]-7-methylimidazo[1,2-a]pyridin-5-yl]spiro[1,3-dihydroindene-2,4'-piperidine]-1-amine.

What is the SMILES notation for (1S)-1'-[8-(2-amino-3-chloro-4-pyridinyl)-7-methylimidazo[1,2-c]pyrimidin-5-yl]spiro[1,3-dihydroindene-2,4'-piperidine]-1-amine;[8-[(2-amino-3-chloro-4-pyridinyl)sulfanyl]-5-[(1S)-1-aminospiro[1,3-dihydroindene-2,4'-piperidine]-1'-yl]-7-methylimidazo[1,2-c]pyrimidin-2-yl]methanol;(1S)-1'-[8-[(2-amino-3-chloro-4-pyridinyl)sulfanyl]-3,7-dimethylimidazo[1,2-c]pyrimidin-5-yl]spiro[1,3-dihydroindene-2,4'-piperidine]-1-amine;(1S)-1'-[8-[(2-chloro-3-pyridinyl)sulfanyl]-7-methylimidazo[1,2-a]pyridin-5-yl]spiro[1,3-dihydroindene-2,4'-piperidine]-1-amine?

The canonical SMILES for (1S)-1'-[8-(2-amino-3-chloro-4-pyridinyl)-7-methylimidazo[1,2-c]pyrimidin-5-yl]spiro[1,3-dihydroindene-2,4'-piperidine]-1-amine;[8-[(2-amino-3-chloro-4-pyridinyl)sulfanyl]-5-[(1S)-1-aminospiro[1,3-dihydroindene-2,4'-piperidine]-1'-yl]-7-methylimidazo[1,2-c]pyrimidin-2-yl]methanol;(1S)-1'-[8-[(2-amino-3-chloro-4-pyridinyl)sulfanyl]-3,7-dimethylimidazo[1,2-c]pyrimidin-5-yl]spiro[1,3-dihydroindene-2,4'-piperidine]-1-amine;(1S)-1'-[8-[(2-chloro-3-pyridinyl)sulfanyl]-7-methylimidazo[1,2-a]pyridin-5-yl]spiro[1,3-dihydroindene-2,4'-piperidine]-1-amine is Cc1cc(N2CCC3(CC2)Cc2ccccc2[C@H]3N)n2ccnc2c1Sc1cccnc1Cl.Cc1nc(N2CCC3(CC2)Cc2ccccc2[C@H]3N)n2c(C)cnc2c1Sc1ccnc(N)c1Cl.Cc1nc(N2CCC3(CC2)Cc2ccccc2[C@H]3N)n2cc(CO)nc2c1Sc1ccnc(N)c1Cl.Cc1nc(N2CCC3(CC2)Cc2ccccc2[C@H]3N)n2ccnc2c1-c1ccnc(N)c1Cl.

What is the InChIKey of (1S)-1'-[8-(2-amino-3-chloro-4-pyridinyl)-7-methylimidazo[1,2-c]pyrimidin-5-yl]spiro[1,3-dihydroindene-2,4'-piperidine]-1-amine;[8-[(2-amino-3-chloro-4-pyridinyl)sulfanyl]-5-[(1S)-1-aminospiro[1,3-dihydroindene-2,4'-piperidine]-1'-yl]-7-methylimidazo[1,2-c]pyrimidin-2-yl]methanol;(1S)-1'-[8-[(2-amino-3-chloro-4-pyridinyl)sulfanyl]-3,7-dimethylimidazo[1,2-c]pyrimidin-5-yl]spiro[1,3-dihydroindene-2,4'-piperidine]-1-amine;(1S)-1'-[8-[(2-chloro-3-pyridinyl)sulfanyl]-7-methylimidazo[1,2-a]pyridin-5-yl]spiro[1,3-dihydroindene-2,4'-piperidine]-1-amine?

The InChIKey is RDTXPGWSLYQXQG-BWPILCAZSA-N. The full InChI is InChI=1S/C26H28ClN7OS.C26H28ClN7S.C26H26ClN5S.C25H26ClN7/c1-15-21(36-19-6-9-30-23(29)20(19)27)24-32-17(14-35)13-34(24)25(31-15)33-10-7-26(8-11-33)12-16-4-2-3-5-18(16)22(26)28;1-15-14-31-24-21(35-19-7-10-30-23(29)20(19)27)16(2)32-25(34(15)24)33-11-8-26(9-12-33)13-17-5-3-4-6-18(17)22(26)28;1-17-15-21(32-14-11-30-25(32)22(17)33-20-7-4-10-29-24(20)27)31-12-8-26(9-13-31)16-18-5-2-3-6-19(18)23(26)28;1-15-19(18-6-9-29-22(28)20(18)26)23-30-10-13-33(23)24(31-15)32-11-7-25(8-12-32)14-16-4-2-3-5-17(16)21(25)27/h2-6,9,13,22,35H,7-8,10-12,14,28H2,1H3,(H2,29,30);3-7,10,14,22H,8-9,11-13,28H2,1-2H3,(H2,29,30);2-7,10-11,14-15,23H,8-9,12-13,16,28H2,1H3;2-6,9-10,13,21H,7-8,11-12,14,27H2,1H3,(H2,28,29)/t2*22-;23-;21-/m1111/s1.

What are the key properties of (1S)-1'-[8-(2-amino-3-chloro-4-pyridinyl)-7-methylimidazo[1,2-c]pyrimidin-5-yl]spiro[1,3-dihydroindene-2,4'-piperidine]-1-amine;[8-[(2-amino-3-chloro-4-pyridinyl)sulfanyl]-5-[(1S)-1-aminospiro[1,3-dihydroindene-2,4'-piperidine]-1'-yl]-7-methylimidazo[1,2-c]pyrimidin-2-yl]methanol;(1S)-1'-[8-[(2-amino-3-chloro-4-pyridinyl)sulfanyl]-3,7-dimethylimidazo[1,2-c]pyrimidin-5-yl]spiro[1,3-dihydroindene-2,4'-piperidine]-1-amine;(1S)-1'-[8-[(2-chloro-3-pyridinyl)sulfanyl]-7-methylimidazo[1,2-a]pyridin-5-yl]spiro[1,3-dihydroindene-2,4'-piperidine]-1-amine?

(1S)-1'-[8-(2-amino-3-chloro-4-pyridinyl)-7-methylimidazo[1,2-c]pyrimidin-5-yl]spiro[1,3-dihydroindene-2,4'-piperidine]-1-amine;[8-[(2-amino-3-chloro-4-pyridinyl)sulfanyl]-5-[(1S)-1-aminospiro[1,3-dihydroindene-2,4'-piperidine]-1'-yl]-7-methylimidazo[1,2-c]pyrimidin-2-yl]methanol;(1S)-1'-[8-[(2-amino-3-chloro-4-pyridinyl)sulfanyl]-3,7-dimethylimidazo[1,2-c]pyrimidin-5-yl]spiro[1,3-dihydroindene-2,4'-piperidine]-1-amine;(1S)-1'-[8-[(2-chloro-3-pyridinyl)sulfanyl]-7-methylimidazo[1,2-a]pyridin-5-yl]spiro[1,3-dihydroindene-2,4'-piperidine]-1-amine has a molecular weight of 1964.19 g/mol, XLogP of 18.99, 12 rotatable bonds, 8 hydrogen bond donors, and 30 hydrogen bond acceptors.

Where does this data come from?

All data for (1S)-1'-[8-(2-amino-3-chloro-4-pyridinyl)-7-methylimidazo[1,2-c]pyrimidin-5-yl]spiro[1,3-dihydroindene-2,4'-piperidine]-1-amine;[8-[(2-amino-3-chloro-4-pyridinyl)sulfanyl]-5-[(1S)-1-aminospiro[1,3-dihydroindene-2,4'-piperidine]-1'-yl]-7-methylimidazo[1,2-c]pyrimidin-2-yl]methanol;(1S)-1'-[8-[(2-amino-3-chloro-4-pyridinyl)sulfanyl]-3,7-dimethylimidazo[1,2-c]pyrimidin-5-yl]spiro[1,3-dihydroindene-2,4'-piperidine]-1-amine;(1S)-1'-[8-[(2-chloro-3-pyridinyl)sulfanyl]-7-methylimidazo[1,2-a]pyridin-5-yl]spiro[1,3-dihydroindene-2,4'-piperidine]-1-amine is sourced from PubChem (CID 165060768), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).