N-[[2-(6-aminopyrimidin-4-yl)phenyl]methyl]-7-(4-bromo-3-chlorobenzoyl)-2-(4-cyclopropyloxyphenyl)-6-methyl-3-oxo-6,8-dihydro-5H-imidazo[1,5-a]pyrazine-1-carboxamide;7-(4-bromo-3-chlorobenzoyl)-2-(4-cyclopropyloxyphenyl)-N-[(2-fluoro-6-pyrimidin-4-ylphenyl)methyl]-6-methyl-3-oxo-6,8-dihydro-5H-imidazo[1,5-a]pyrazine-1-carboxamide;7-(4-bromo-3-chlorobenzoyl)-2-(4-cyclopropyloxyphenyl)-6-methyl-N-[[2-(5-methyl-1,3,4-oxadiazol-2-yl)phenyl]methyl]-3-oxo-6,8-dihydro-5H-imidazo[1,5-a]pyrazine-1-carboxamide;7-(4-bromo-3-chlorobenzoyl)-2-(4-cyclopropyloxyphenyl)-6-methyl-N-[[2-(4-methylpyrazol-1-yl)phenyl]methyl]-3-oxo-6,8-dihydro-5H-imidazo[1,5-a]pyrazine-1-carboxamide;7-(4-bromo-3-chlorobenzoyl)-2-(4-cyclopropyloxyphenyl)-6-methyl-3-oxo-N-[(2-pyridazin-3-ylphenyl)methyl]-6,8-dihydro-5H-imidazo[1,5-a]pyrazine-1-carboxamide;7-(4-bromo-3-chlorobenzoyl)-2-(4-cyclopropyloxyphenyl)-6-methyl-3-oxo-N-[(2-pyrimidin-2-ylphenyl)methyl]-6,8-dihydro-5H-imidazo[1,5-a]pyrazine-1-carboxamide;7-(4-bromo-3-chlorobenzoyl)-6-methyl-3-oxo-2-(4-pyrazol-1-ylphenyl)-N-[(2-pyrimidin-4-ylphenyl)methyl]-6,8-dihydro-5H-imidazo[1,5-a]pyrazine-1-carboxamide;7-(4-bromo-3-cyanobenzoyl)-2-(4-cyclopropyloxyphenyl)-6-methyl-N-[[2-(5-methyl-1,3,4-oxadiazol-2-yl)phenyl]methyl]-3-oxo-6,8-dihydro-5H-imidazo[1,5-a]pyrazine-1-carboxamide

C279H240Br8Cl7FN52O33 — CID 165061385

IUPACN-[[2-(6-aminopyrimidin-4-yl)phenyl]methyl]-7-(4-bromo-3-chlorobenzoyl)-2-(4-cyclopropyloxyphenyl)-6-methyl-3-oxo-6,8-dihydro-5H-imidazo[1,5-a]pyrazine-1-carboxamide;7-(4-bromo-3-chlorobenzoyl)-2-(4-cyclopropyloxyphenyl)-N-[(2-fluoro-6-pyrimidin-4-ylphenyl)methyl]-6-methyl-3-oxo-6,8-dihydro-5H-imidazo[1,5-a]pyrazine-1-carboxamide;7-(4-bromo-3-chlorobenzoyl)-2-(4-cyclopropyloxyphenyl)-6-methyl-N-[[2-(5-methyl-1,3,4-oxadiazol-2-yl)phenyl]methyl]-3-oxo-6,8-dihydro-5H-imidazo[1,5-a]pyrazine-1-carboxamide;7-(4-bromo-3-chlorobenzoyl)-2-(4-cyclopropyloxyphenyl)-6-methyl-N-[[2-(4-methylpyrazol-1-yl)phenyl]methyl]-3-oxo-6,8-dihydro-5H-imidazo[1,5-a]pyrazine-1-carboxamide;7-(4-bromo-3-chlorobenzoyl)-2-(4-cyclopropyloxyphenyl)-6-methyl-3-oxo-N-[(2-pyridazin-3-ylphenyl)methyl]-6,8-dihydro-5H-imidazo[1,5-a]pyrazine-1-carboxamide;7-(4-bromo-3-chlorobenzoyl)-2-(4-cyclopropyloxyphenyl)-6-methyl-3-oxo-N-[(2-pyrimidin-2-ylphenyl)methyl]-6,8-dihydro-5H-imidazo[1,5-a]pyrazine-1-carboxamide;7-(4-bromo-3-chlorobenzoyl)-6-methyl-3-oxo-2-(4-pyrazol-1-ylphenyl)-N-[(2-pyrimidin-4-ylphenyl)methyl]-6,8-dihydro-5H-imidazo[1,5-a]pyrazine-1-carboxamide;7-(4-bromo-3-cyanobenzoyl)-2-(4-cyclopropyloxyphenyl)-6-methyl-N-[[2-(5-methyl-1,3,4-oxadiazol-2-yl)phenyl]methyl]-3-oxo-6,8-dihydro-5H-imidazo[1,5-a]pyrazine-1-carboxamide
SMILESCC1Cn2c(c(C(=O)NCc3c(F)cccc3-c3ccncn3)n(-c3ccc(OC4CC4)cc3)c2=O)CN1C(=O)c1ccc(Br)c(Cl)c1.CC1Cn2c(c(C(=O)NCc3ccccc3-c3cc(N)ncn3)n(-c3ccc(OC4CC4)cc3)c2=O)CN1C(=O)c1ccc(Br)c(Cl)c1.CC1Cn2c(c(C(=O)NCc3ccccc3-c3cccnn3)n(-c3ccc(OC4CC4)cc3)c2=O)CN1C(=O)c1ccc(Br)c(Cl)c1.CC1Cn2c(c(C(=O)NCc3ccccc3-c3ccncn3)n(-c3ccc(-n4cccn4)cc3)c2=O)CN1C(=O)c1ccc(Br)c(Cl)c1.CC1Cn2c(c(C(=O)NCc3ccccc3-c3ncccn3)n(-c3ccc(OC4CC4)cc3)c2=O)CN1C(=O)c1ccc(Br)c(Cl)c1.Cc1cnn(-c2ccccc2CNC(=O)c2c3n(c(=O)n2-c2ccc(OC4CC4)cc2)CC(C)N(C(=O)c2ccc(Br)c(Cl)c2)C3)c1.Cc1nnc(-c2ccccc2CNC(=O)c2c3n(c(=O)n2-c2ccc(OC4CC4)cc2)CC(C)N(C(=O)c2ccc(Br)c(C#N)c2)C3)o1.Cc1nnc(-c2ccccc2CNC(=O)c2c3n(c(=O)n2-c2ccc(OC4CC4)cc2)CC(C)N(C(=O)c2ccc(Br)c(Cl)c2)C3)o1
InChIInChI=1S/C35H29BrClFN6O4.C35H28BrClN8O3.C35H31BrClN7O4.C35H32BrClN6O4.2C35H30BrClN6O4.C35H30BrN7O5.C34H30BrClN6O5/c1-20-17-43-31(18-42(20)34(46)21-5-12-27(36)28(37)15-21)32(44(35(43)47)22-6-8-23(9-7-22)48-24-10-11-24)33(45)40-16-26-25(3-2-4-29(26)38)30-13-14-39-19-41-30;1-22-19-43-31(20-42(22)34(47)23-7-12-28(36)29(37)17-23)32(45(35(43)48)26-10-8-25(9-11-26)44-16-4-14-41-44)33(46)39-18-24-5-2-3-6-27(24)30-13-15-38-21-40-30;1-20-17-43-30(18-42(20)34(46)21-6-13-27(36)28(37)14-21)32(44(35(43)47)23-7-9-24(10-8-23)48-25-11-12-25)33(45)39-16-22-4-2-3-5-26(22)29-15-31(38)41-19-40-29;1-21-16-39-42(18-21)30-6-4-3-5-24(30)17-38-33(44)32-31-20-40(34(45)23-7-14-28(36)29(37)15-23)22(2)19-41(31)35(46)43(32)25-8-10-26(11-9-25)47-27-12-13-27;1-21-19-42-30(20-41(21)34(45)22-7-14-28(36)29(37)17-22)31(43(35(42)46)24-8-10-25(11-9-24)47-26-12-13-26)33(44)40-18-23-5-2-3-6-27(23)32-38-15-4-16-39-32;1-21-19-42-31(20-41(21)34(45)22-8-15-28(36)29(37)17-22)32(43(35(42)46)24-9-11-25(12-10-24)47-26-13-14-26)33(44)38-18-23-5-2-3-6-27(23)30-7-4-16-39-40-30;1-20-18-42-30(19-41(20)34(45)22-7-14-29(36)24(15-22)16-37)31(43(35(42)46)25-8-10-26(11-9-25)48-27-12-13-27)32(44)38-17-23-5-3-4-6-28(23)33-40-39-21(2)47-33;1-19-17-41-29(18-40(19)33(44)21-7-14-27(35)28(36)15-21)30(42(34(41)45)23-8-10-24(11-9-23)47-25-12-13-25)31(43)37-16-22-5-3-4-6-26(22)32-39-38-20(2)46-32/h2-9,12-15,19-20,24H,10-11,16-18H2,1H3,(H,40,45);2-17,21-22H,18-20H2,1H3,(H,39,46);2-10,13-15,19-20,25H,11-12,16-18H2,1H3,(H,39,45)(H2,38,40,41);3-11,14-16,18,22,27H,12-13,17,19-20H2,1-2H3,(H,38,44);2-11,14-17,21,26H,12-13,18-20H2,1H3,(H,40,44);2-12,15-17,21,26H,13-14,18-20H2,1H3,(H,38,44);3-11,14-15,20,27H,12-13,17-19H2,1-2H3,(H,38,44);3-11,14-15,19,25H,12-13,16-18H2,1-2H3,(H,37,43)
InChIKeyRGNLTYVXGDMTRG-UHFFFAOYSA-N
MW5755.72 g/mol
LogP46.64
Rot. Bonds63

About N-[[2-(6-aminopyrimidin-4-yl)phenyl]methyl]-7-(4-bromo-3-chlorobenzoyl)-2-(4-cyclopropyloxyphenyl)-6-methyl-3-oxo-6,8-dihydro-5H-imidazo[1,5-a]pyrazine-1-carboxamide;7-(4-bromo-3-chlorobenzoyl)-2-(4-cyclopropyloxyphenyl)-N-[(2-fluoro-6-pyrimidin-4-ylphenyl)methyl]-6-methyl-3-oxo-6,8-dihydro-5H-imidazo[1,5-a]pyrazine-1-carboxamide;7-(4-bromo-3-chlorobenzoyl)-2-(4-cyclopropyloxyphenyl)-6-methyl-N-[[2-(5-methyl-1,3,4-oxadiazol-2-yl)phenyl]methyl]-3-oxo-6,8-dihydro-5H-imidazo[1,5-a]pyrazine-1-carboxamide;7-(4-bromo-3-chlorobenzoyl)-2-(4-cyclopropyloxyphenyl)-6-methyl-N-[[2-(4-methylpyrazol-1-yl)phenyl]methyl]-3-oxo-6,8-dihydro-5H-imidazo[1,5-a]pyrazine-1-carboxamide;7-(4-bromo-3-chlorobenzoyl)-2-(4-cyclopropyloxyphenyl)-6-methyl-3-oxo-N-[(2-pyridazin-3-ylphenyl)methyl]-6,8-dihydro-5H-imidazo[1,5-a]pyrazine-1-carboxamide;7-(4-bromo-3-chlorobenzoyl)-2-(4-cyclopropyloxyphenyl)-6-methyl-3-oxo-N-[(2-pyrimidin-2-ylphenyl)methyl]-6,8-dihydro-5H-imidazo[1,5-a]pyrazine-1-carboxamide;7-(4-bromo-3-chlorobenzoyl)-6-methyl-3-oxo-2-(4-pyrazol-1-ylphenyl)-N-[(2-pyrimidin-4-ylphenyl)methyl]-6,8-dihydro-5H-imidazo[1,5-a]pyrazine-1-carboxamide;7-(4-bromo-3-cyanobenzoyl)-2-(4-cyclopropyloxyphenyl)-6-methyl-N-[[2-(5-methyl-1,3,4-oxadiazol-2-yl)phenyl]methyl]-3-oxo-6,8-dihydro-5H-imidazo[1,5-a]pyrazine-1-carboxamide

N-[[2-(6-aminopyrimidin-4-yl)phenyl]methyl]-7-(4-bromo-3-chlorobenzoyl)-2-(4-cyclopropyloxyphenyl)-6-methyl-3-oxo-6,8-dihydro-5H-imidazo[1,5-a]pyrazine-1-carboxamide;7-(4-bromo-3-chlorobenzoyl)-2-(4-cyclopropyloxyphenyl)-N-[(2-fluoro-6-pyrimidin-4-ylphenyl)methyl]-6-methyl-3-oxo-6,8-dihydro-5H-imidazo[1,5-a]pyrazine-1-carboxamide;7-(4-bromo-3-chlorobenzoyl)-2-(4-cyclopropyloxyphenyl)-6-methyl-N-[[2-(5-methyl-1,3,4-oxadiazol-2-yl)phenyl]methyl]-3-oxo-6,8-dihydro-5H-imidazo[1,5-a]pyrazine-1-carboxamide;7-(4-bromo-3-chlorobenzoyl)-2-(4-cyclopropyloxyphenyl)-6-methyl-N-[[2-(4-methylpyrazol-1-yl)phenyl]methyl]-3-oxo-6,8-dihydro-5H-imidazo[1,5-a]pyrazine-1-carboxamide;7-(4-bromo-3-chlorobenzoyl)-2-(4-cyclopropyloxyphenyl)-6-methyl-3-oxo-N-[(2-pyridazin-3-ylphenyl)methyl]-6,8-dihydro-5H-imidazo[1,5-a]pyrazine-1-carboxamide;7-(4-bromo-3-chlorobenzoyl)-2-(4-cyclopropyloxyphenyl)-6-methyl-3-oxo-N-[(2-pyrimidin-2-ylphenyl)methyl]-6,8-dihydro-5H-imidazo[1,5-a]pyrazine-1-carboxamide;7-(4-bromo-3-chlorobenzoyl)-6-methyl-3-oxo-2-(4-pyrazol-1-ylphenyl)-N-[(2-pyrimidin-4-ylphenyl)methyl]-6,8-dihydro-5H-imidazo[1,5-a]pyrazine-1-carboxamide;7-(4-bromo-3-cyanobenzoyl)-2-(4-cyclopropyloxyphenyl)-6-methyl-N-[[2-(5-methyl-1,3,4-oxadiazol-2-yl)phenyl]methyl]-3-oxo-6,8-dihydro-5H-imidazo[1,5-a]pyrazine-1-carboxamide (PubChem CID 165061385) has the molecular formula C279H240Br8Cl7FN52O33 and a molecular weight of 5755.72 g/mol. Its IUPAC name is N-[[2-(6-aminopyrimidin-4-yl)phenyl]methyl]-7-(4-bromo-3-chlorobenzoyl)-2-(4-cyclopropyloxyphenyl)-6-methyl-3-oxo-6,8-dihydro-5H-imidazo[1,5-a]pyrazine-1-carboxamide;7-(4-bromo-3-chlorobenzoyl)-2-(4-cyclopropyloxyphenyl)-N-[(2-fluoro-6-pyrimidin-4-ylphenyl)methyl]-6-methyl-3-oxo-6,8-dihydro-5H-imidazo[1,5-a]pyrazine-1-carboxamide;7-(4-bromo-3-chlorobenzoyl)-2-(4-cyclopropyloxyphenyl)-6-methyl-N-[[2-(5-methyl-1,3,4-oxadiazol-2-yl)phenyl]methyl]-3-oxo-6,8-dihydro-5H-imidazo[1,5-a]pyrazine-1-carboxamide;7-(4-bromo-3-chlorobenzoyl)-2-(4-cyclopropyloxyphenyl)-6-methyl-N-[[2-(4-methylpyrazol-1-yl)phenyl]methyl]-3-oxo-6,8-dihydro-5H-imidazo[1,5-a]pyrazine-1-carboxamide;7-(4-bromo-3-chlorobenzoyl)-2-(4-cyclopropyloxyphenyl)-6-methyl-3-oxo-N-[(2-pyridazin-3-ylphenyl)methyl]-6,8-dihydro-5H-imidazo[1,5-a]pyrazine-1-carboxamide;7-(4-bromo-3-chlorobenzoyl)-2-(4-cyclopropyloxyphenyl)-6-methyl-3-oxo-N-[(2-pyrimidin-2-ylphenyl)methyl]-6,8-dihydro-5H-imidazo[1,5-a]pyrazine-1-carboxamide;7-(4-bromo-3-chlorobenzoyl)-6-methyl-3-oxo-2-(4-pyrazol-1-ylphenyl)-N-[(2-pyrimidin-4-ylphenyl)methyl]-6,8-dihydro-5H-imidazo[1,5-a]pyrazine-1-carboxamide;7-(4-bromo-3-cyanobenzoyl)-2-(4-cyclopropyloxyphenyl)-6-methyl-N-[[2-(5-methyl-1,3,4-oxadiazol-2-yl)phenyl]methyl]-3-oxo-6,8-dihydro-5H-imidazo[1,5-a]pyrazine-1-carboxamide.

Molecular Properties

Compound NameN-[[2-(6-aminopyrimidin-4-yl)phenyl]methyl]-7-(4-bromo-3-chlorobenzoyl)-2-(4-cyclopropyloxyphenyl)-6-methyl-3-oxo-6,8-dihydro-5H-imidazo[1,5-a]pyrazine-1-carboxamide;7-(4-bromo-3-chlorobenzoyl)-2-(4-cyclopropyloxyphenyl)-N-[(2-fluoro-6-pyrimidin-4-ylphenyl)methyl]-6-methyl-3-oxo-6,8-dihydro-5H-imidazo[1,5-a]pyrazine-1-carboxamide;7-(4-bromo-3-chlorobenzoyl)-2-(4-cyclopropyloxyphenyl)-6-methyl-N-[[2-(5-methyl-1,3,4-oxadiazol-2-yl)phenyl]methyl]-3-oxo-6,8-dihydro-5H-imidazo[1,5-a]pyrazine-1-carboxamide;7-(4-bromo-3-chlorobenzoyl)-2-(4-cyclopropyloxyphenyl)-6-methyl-N-[[2-(4-methylpyrazol-1-yl)phenyl]methyl]-3-oxo-6,8-dihydro-5H-imidazo[1,5-a]pyrazine-1-carboxamide;7-(4-bromo-3-chlorobenzoyl)-2-(4-cyclopropyloxyphenyl)-6-methyl-3-oxo-N-[(2-pyridazin-3-ylphenyl)methyl]-6,8-dihydro-5H-imidazo[1,5-a]pyrazine-1-carboxamide;7-(4-bromo-3-chlorobenzoyl)-2-(4-cyclopropyloxyphenyl)-6-methyl-3-oxo-N-[(2-pyrimidin-2-ylphenyl)methyl]-6,8-dihydro-5H-imidazo[1,5-a]pyrazine-1-carboxamide;7-(4-bromo-3-chlorobenzoyl)-6-methyl-3-oxo-2-(4-pyrazol-1-ylphenyl)-N-[(2-pyrimidin-4-ylphenyl)methyl]-6,8-dihydro-5H-imidazo[1,5-a]pyrazine-1-carboxamide;7-(4-bromo-3-cyanobenzoyl)-2-(4-cyclopropyloxyphenyl)-6-methyl-N-[[2-(5-methyl-1,3,4-oxadiazol-2-yl)phenyl]methyl]-3-oxo-6,8-dihydro-5H-imidazo[1,5-a]pyrazine-1-carboxamide
PubChem CID165061385
Molecular FormulaC279H240Br8Cl7FN52O33
Molecular Weight5755.72 g/mol
Exact Mass5741.00
IUPAC NameN-[[2-(6-aminopyrimidin-4-yl)phenyl]methyl]-7-(4-bromo-3-chlorobenzoyl)-2-(4-cyclopropyloxyphenyl)-6-methyl-3-oxo-6,8-dihydro-5H-imidazo[1,5-a]pyrazine-1-carboxamide;7-(4-bromo-3-chlorobenzoyl)-2-(4-cyclopropyloxyphenyl)-N-[(2-fluoro-6-pyrimidin-4-ylphenyl)methyl]-6-methyl-3-oxo-6,8-dihydro-5H-imidazo[1,5-a]pyrazine-1-carboxamide;7-(4-bromo-3-chlorobenzoyl)-2-(4-cyclopropyloxyphenyl)-6-methyl-N-[[2-(5-methyl-1,3,4-oxadiazol-2-yl)phenyl]methyl]-3-oxo-6,8-dihydro-5H-imidazo[1,5-a]pyrazine-1-carboxamide;7-(4-bromo-3-chlorobenzoyl)-2-(4-cyclopropyloxyphenyl)-6-methyl-N-[[2-(4-methylpyrazol-1-yl)phenyl]methyl]-3-oxo-6,8-dihydro-5H-imidazo[1,5-a]pyrazine-1-carboxamide;7-(4-bromo-3-chlorobenzoyl)-2-(4-cyclopropyloxyphenyl)-6-methyl-3-oxo-N-[(2-pyridazin-3-ylphenyl)methyl]-6,8-dihydro-5H-imidazo[1,5-a]pyrazine-1-carboxamide;7-(4-bromo-3-chlorobenzoyl)-2-(4-cyclopropyloxyphenyl)-6-methyl-3-oxo-N-[(2-pyrimidin-2-ylphenyl)methyl]-6,8-dihydro-5H-imidazo[1,5-a]pyrazine-1-carboxamide;7-(4-bromo-3-chlorobenzoyl)-6-methyl-3-oxo-2-(4-pyrazol-1-ylphenyl)-N-[(2-pyrimidin-4-ylphenyl)methyl]-6,8-dihydro-5H-imidazo[1,5-a]pyrazine-1-carboxamide;7-(4-bromo-3-cyanobenzoyl)-2-(4-cyclopropyloxyphenyl)-6-methyl-N-[[2-(5-methyl-1,3,4-oxadiazol-2-yl)phenyl]methyl]-3-oxo-6,8-dihydro-5H-imidazo[1,5-a]pyrazine-1-carboxamide
SMILESCC1Cn2c(c(C(=O)NCc3c(F)cccc3-c3ccncn3)n(-c3ccc(OC4CC4)cc3)c2=O)CN1C(=O)c1ccc(Br)c(Cl)c1.CC1Cn2c(c(C(=O)NCc3ccccc3-c3cc(N)ncn3)n(-c3ccc(OC4CC4)cc3)c2=O)CN1C(=O)c1ccc(Br)c(Cl)c1.CC1Cn2c(c(C(=O)NCc3ccccc3-c3cccnn3)n(-c3ccc(OC4CC4)cc3)c2=O)CN1C(=O)c1ccc(Br)c(Cl)c1.CC1Cn2c(c(C(=O)NCc3ccccc3-c3ccncn3)n(-c3ccc(-n4cccn4)cc3)c2=O)CN1C(=O)c1ccc(Br)c(Cl)c1.CC1Cn2c(c(C(=O)NCc3ccccc3-c3ncccn3)n(-c3ccc(OC4CC4)cc3)c2=O)CN1C(=O)c1ccc(Br)c(Cl)c1.Cc1cnn(-c2ccccc2CNC(=O)c2c3n(c(=O)n2-c2ccc(OC4CC4)cc2)CC(C)N(C(=O)c2ccc(Br)c(Cl)c2)C3)c1.Cc1nnc(-c2ccccc2CNC(=O)c2c3n(c(=O)n2-c2ccc(OC4CC4)cc2)CC(C)N(C(=O)c2ccc(Br)c(C#N)c2)C3)o1.Cc1nnc(-c2ccccc2CNC(=O)c2c3n(c(=O)n2-c2ccc(OC4CC4)cc2)CC(C)N(C(=O)c2ccc(Br)c(Cl)c2)C3)o1
InChIInChI=1S/C35H29BrClFN6O4.C35H28BrClN8O3.C35H31BrClN7O4.C35H32BrClN6O4.2C35H30BrClN6O4.C35H30BrN7O5.C34H30BrClN6O5/c1-20-17-43-31(18-42(20)34(46)21-5-12-27(36)28(37)15-21)32(44(35(43)47)22-6-8-23(9-7-22)48-24-10-11-24)33(45)40-16-26-25(3-2-4-29(26)38)30-13-14-39-19-41-30;1-22-19-43-31(20-42(22)34(47)23-7-12-28(36)29(37)17-23)32(45(35(43)48)26-10-8-25(9-11-26)44-16-4-14-41-44)33(46)39-18-24-5-2-3-6-27(24)30-13-15-38-21-40-30;1-20-17-43-30(18-42(20)34(46)21-6-13-27(36)28(37)14-21)32(44(35(43)47)23-7-9-24(10-8-23)48-25-11-12-25)33(45)39-16-22-4-2-3-5-26(22)29-15-31(38)41-19-40-29;1-21-16-39-42(18-21)30-6-4-3-5-24(30)17-38-33(44)32-31-20-40(34(45)23-7-14-28(36)29(37)15-23)22(2)19-41(31)35(46)43(32)25-8-10-26(11-9-25)47-27-12-13-27;1-21-19-42-30(20-41(21)34(45)22-7-14-28(36)29(37)17-22)31(43(35(42)46)24-8-10-25(11-9-24)47-26-12-13-26)33(44)40-18-23-5-2-3-6-27(23)32-38-15-4-16-39-32;1-21-19-42-31(20-41(21)34(45)22-8-15-28(36)29(37)17-22)32(43(35(42)46)24-9-11-25(12-10-24)47-26-13-14-26)33(44)38-18-23-5-2-3-6-27(23)30-7-4-16-39-40-30;1-20-18-42-30(19-41(20)34(45)22-7-14-29(36)24(15-22)16-37)31(43(35(42)46)25-8-10-26(11-9-25)48-27-12-13-27)32(44)38-17-23-5-3-4-6-28(23)33-40-39-21(2)47-33;1-19-17-41-29(18-40(19)33(44)21-7-14-27(35)28(36)15-21)30(42(34(41)45)23-8-10-24(11-9-23)47-25-12-13-25)31(43)37-16-22-5-3-4-6-26(22)32-39-38-20(2)46-32/h2-9,12-15,19-20,24H,10-11,16-18H2,1H3,(H,40,45);2-17,21-22H,18-20H2,1H3,(H,39,46);2-10,13-15,19-20,25H,11-12,16-18H2,1H3,(H,39,45)(H2,38,40,41);3-11,14-16,18,22,27H,12-13,17,19-20H2,1-2H3,(H,38,44);2-11,14-17,21,26H,12-13,18-20H2,1H3,(H,40,44);2-12,15-17,21,26H,13-14,18-20H2,1H3,(H,38,44);3-11,14-15,20,27H,12-13,17-19H2,1-2H3,(H,38,44);3-11,14-15,19,25H,12-13,16-18H2,1-2H3,(H,37,43)
InChIKeyRGNLTYVXGDMTRG-UHFFFAOYSA-N
XLogP46.64
TPSA967.52 Ų
H-Bond Donors9
H-Bond Acceptors69
Rotatable Bonds63
Heavy Atoms380
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5005755.72
LogP ≤ 546.64
H-Bond Donors ≤ 59
H-Bond Acceptors ≤ 1069

Analyze N-[[2-(6-aminopyrimidin-4-yl)phenyl]methyl]-7-(4-bromo-3-chlorobenzoyl)-2-(4-cyclopropyloxyphenyl)-6-methyl-3-oxo-6,8-dihydro-5H-imidazo[1,5-a]pyrazine-1-carboxamide;7-(4-bromo-3-chlorobenzoyl)-2-(4-cyclopropyloxyphenyl)-N-[(2-fluoro-6-pyrimidin-4-ylphenyl)methyl]-6-methyl-3-oxo-6,8-dihydro-5H-imidazo[1,5-a]pyrazine-1-carboxamide;7-(4-bromo-3-chlorobenzoyl)-2-(4-cyclopropyloxyphenyl)-6-methyl-N-[[2-(5-methyl-1,3,4-oxadiazol-2-yl)phenyl]methyl]-3-oxo-6,8-dihydro-5H-imidazo[1,5-a]pyrazine-1-carboxamide;7-(4-bromo-3-chlorobenzoyl)-2-(4-cyclopropyloxyphenyl)-6-methyl-N-[[2-(4-methylpyrazol-1-yl)phenyl]methyl]-3-oxo-6,8-dihydro-5H-imidazo[1,5-a]pyrazine-1-carboxamide;7-(4-bromo-3-chlorobenzoyl)-2-(4-cyclopropyloxyphenyl)-6-methyl-3-oxo-N-[(2-pyridazin-3-ylphenyl)methyl]-6,8-dihydro-5H-imidazo[1,5-a]pyrazine-1-carboxamide;7-(4-bromo-3-chlorobenzoyl)-2-(4-cyclopropyloxyphenyl)-6-methyl-3-oxo-N-[(2-pyrimidin-2-ylphenyl)methyl]-6,8-dihydro-5H-imidazo[1,5-a]pyrazine-1-carboxamide;7-(4-bromo-3-chlorobenzoyl)-6-methyl-3-oxo-2-(4-pyrazol-1-ylphenyl)-N-[(2-pyrimidin-4-ylphenyl)methyl]-6,8-dihydro-5H-imidazo[1,5-a]pyrazine-1-carboxamide;7-(4-bromo-3-cyanobenzoyl)-2-(4-cyclopropyloxyphenyl)-6-methyl-N-[[2-(5-methyl-1,3,4-oxadiazol-2-yl)phenyl]methyl]-3-oxo-6,8-dihydro-5H-imidazo[1,5-a]pyrazine-1-carboxamide with MolForge

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Related Compounds

7-(4-bromo-3-chlorobenzoyl)-2-(4-cyclopropyloxyphenyl)-N-[(2-fluoro-6-pyridazin-3-ylphenyl)methyl]-6-methyl-3-oxo-6,8-dihydro-5H-imidazo[1,5-a]pyrazine-1-carboxamide
CID 164739229
(6S)-7-(4-bromo-3-chlorobenzoyl)-2-(4-cyclopropyloxyphenyl)-6-methyl-3-oxo-N-[(2-pyrimidin-2-ylphenyl)methyl]-6,8-dihydro-5H-imidazo[1,5-a]pyrazine-1-carboxamide;(6R)-7-(4-bromo-3-chlorobenzoyl)-2-(4-cyclopropyloxyphenyl)-6-methyl-3-oxo-N-[(2-pyrimidin-2-ylphenyl)methyl]-6,8-dihydro-5H-imidazo[1,5-a]pyrazine-1-carboxamide
CID 165080427
(6R)-N-[[2-(6-amino-2-pyridinyl)phenyl]methyl]-7-(4-bromo-3-chlorobenzoyl)-2-(4-cyclopropyloxyphenyl)-6-methyl-3-oxo-6,8-dihydro-5H-imidazo[1,5-a]pyrazine-1-carboxamide
CID 164739271
(6R)-N-[[2-(4-aminopyrimidin-2-yl)-6-fluorophenyl]methyl]-7-(4-bromo-3-chlorobenzoyl)-2-(4-cyclopropyloxyphenyl)-6-methyl-3-oxo-6,8-dihydro-5H-imidazo[1,5-a]pyrazine-1-carboxamide
CID 164739151
(6S)-N-[[2-(2-aminopyrimidin-4-yl)phenyl]methyl]-7-(4-bromo-3-chlorobenzoyl)-2-(4-cyclopropyloxyphenyl)-6-methyl-3-oxo-6,8-dihydro-5H-imidazo[1,5-a]pyrazine-1-carboxamide
CID 164739234
(6R)-7-[4-bromo-3-(trifluoromethyl)benzoyl]-2-(4-cyclopropyloxyphenyl)-N-[[2-fluoro-6-(5-methyl-1,3,4-oxadiazol-2-yl)phenyl]methyl]-6-methyl-3-oxo-6,8-dihydro-5H-imidazo[1,5-a]pyrazine-1-carboxamide
CID 167027549
7-(4-bromo-3-chlorobenzoyl)-2-(4-cyclopropyloxyphenyl)-6-methyl-3-oxo-N-[[2-(1,2,4-triazol-1-yl)phenyl]methyl]-6,8-dihydro-5H-imidazo[1,5-a]pyrazine-1-carboxamide
CID 155285403
7-(4-bromo-3-chlorobenzoyl)-2-(4-cyclopropyloxyphenyl)-6-methyl-N-[[2-(1-methylpyrazol-3-yl)phenyl]methyl]-3-oxo-6,8-dihydro-5H-imidazo[1,5-a]pyrazine-1-carboxamide
CID 164739163
(6S)-7-(4-bromo-3-methylbenzoyl)-2-[4-(2-hydroxy-2-methylpropoxy)phenyl]-6-methyl-3-oxo-N-[(2-pyrimidin-4-ylphenyl)methyl]-6,8-dihydro-5H-imidazo[1,5-a]pyrazine-1-carboxamide
CID 165077775
7-(4-bromo-3-methylbenzoyl)-2-[4-(2-hydroxy-2-methylpropoxy)phenyl]-6-methyl-3-oxo-N-[(2-pyridazin-3-ylphenyl)methyl]-6,8-dihydro-5H-imidazo[1,5-a]pyrazine-1-carboxamide;bis(7-(4-bromo-3-methylbenzoyl)-2-[4-(2-hydroxy-2-methylpropoxy)phenyl]-6-methyl-3-oxo-N-[(2-pyrimidin-4-ylphenyl)methyl]-6,8-dihydro-5H-imidazo[1,5-a]pyrazine-1-carboxamide);7-(4-bromo-3-methylbenzoyl)-6-methyl-2-[4-(1-methyl-1,6-diazaspiro[3.3]heptan-6-yl)phenyl]-3-oxo-N-[(2-pyrimidin-4-ylphenyl)methyl]-6,8-dihydro-5H-imidazo[1,5-a]pyrazine-1-carboxamide
CID 164980504
(6S)-2-(2-amino-1,3-benzoxazol-5-yl)-7-(4-bromo-3-methylbenzoyl)-6-methyl-3-oxo-N-[(2-pyrimidin-4-ylphenyl)methyl]-6,8-dihydro-5H-imidazo[1,5-a]pyrazine-1-carboxamide;(6R)-2-(2-amino-1,3-benzoxazol-5-yl)-7-(4-bromo-3-methylbenzoyl)-6-methyl-3-oxo-N-[(2-pyrimidin-4-ylphenyl)methyl]-6,8-dihydro-5H-imidazo[1,5-a]pyrazine-1-carboxamide
CID 165025163
(6S)-7-(4-bromo-3-methylbenzoyl)-6-methyl-3-oxo-N-[(2-pyrimidin-4-ylphenyl)methyl]-2-[4-[(2R)-3,3,3-trifluoro-2-hydroxy-2-methylpropoxy]phenyl]-6,8-dihydro-5H-imidazo[1,5-a]pyrazine-1-carboxamide
CID 165079318

Frequently Asked Questions

What is the IUPAC name of N-[[2-(6-aminopyrimidin-4-yl)phenyl]methyl]-7-(4-bromo-3-chlorobenzoyl)-2-(4-cyclopropyloxyphenyl)-6-methyl-3-oxo-6,8-dihydro-5H-imidazo[1,5-a]pyrazine-1-carboxamide;7-(4-bromo-3-chlorobenzoyl)-2-(4-cyclopropyloxyphenyl)-N-[(2-fluoro-6-pyrimidin-4-ylphenyl)methyl]-6-methyl-3-oxo-6,8-dihydro-5H-imidazo[1,5-a]pyrazine-1-carboxamide;7-(4-bromo-3-chlorobenzoyl)-2-(4-cyclopropyloxyphenyl)-6-methyl-N-[[2-(5-methyl-1,3,4-oxadiazol-2-yl)phenyl]methyl]-3-oxo-6,8-dihydro-5H-imidazo[1,5-a]pyrazine-1-carboxamide;7-(4-bromo-3-chlorobenzoyl)-2-(4-cyclopropyloxyphenyl)-6-methyl-N-[[2-(4-methylpyrazol-1-yl)phenyl]methyl]-3-oxo-6,8-dihydro-5H-imidazo[1,5-a]pyrazine-1-carboxamide;7-(4-bromo-3-chlorobenzoyl)-2-(4-cyclopropyloxyphenyl)-6-methyl-3-oxo-N-[(2-pyridazin-3-ylphenyl)methyl]-6,8-dihydro-5H-imidazo[1,5-a]pyrazine-1-carboxamide;7-(4-bromo-3-chlorobenzoyl)-2-(4-cyclopropyloxyphenyl)-6-methyl-3-oxo-N-[(2-pyrimidin-2-ylphenyl)methyl]-6,8-dihydro-5H-imidazo[1,5-a]pyrazine-1-carboxamide;7-(4-bromo-3-chlorobenzoyl)-6-methyl-3-oxo-2-(4-pyrazol-1-ylphenyl)-N-[(2-pyrimidin-4-ylphenyl)methyl]-6,8-dihydro-5H-imidazo[1,5-a]pyrazine-1-carboxamide;7-(4-bromo-3-cyanobenzoyl)-2-(4-cyclopropyloxyphenyl)-6-methyl-N-[[2-(5-methyl-1,3,4-oxadiazol-2-yl)phenyl]methyl]-3-oxo-6,8-dihydro-5H-imidazo[1,5-a]pyrazine-1-carboxamide?
The IUPAC name of N-[[2-(6-aminopyrimidin-4-yl)phenyl]methyl]-7-(4-bromo-3-chlorobenzoyl)-2-(4-cyclopropyloxyphenyl)-6-methyl-3-oxo-6,8-dihydro-5H-imidazo[1,5-a]pyrazine-1-carboxamide;7-(4-bromo-3-chlorobenzoyl)-2-(4-cyclopropyloxyphenyl)-N-[(2-fluoro-6-pyrimidin-4-ylphenyl)methyl]-6-methyl-3-oxo-6,8-dihydro-5H-imidazo[1,5-a]pyrazine-1-carboxamide;7-(4-bromo-3-chlorobenzoyl)-2-(4-cyclopropyloxyphenyl)-6-methyl-N-[[2-(5-methyl-1,3,4-oxadiazol-2-yl)phenyl]methyl]-3-oxo-6,8-dihydro-5H-imidazo[1,5-a]pyrazine-1-carboxamide;7-(4-bromo-3-chlorobenzoyl)-2-(4-cyclopropyloxyphenyl)-6-methyl-N-[[2-(4-methylpyrazol-1-yl)phenyl]methyl]-3-oxo-6,8-dihydro-5H-imidazo[1,5-a]pyrazine-1-carboxamide;7-(4-bromo-3-chlorobenzoyl)-2-(4-cyclopropyloxyphenyl)-6-methyl-3-oxo-N-[(2-pyridazin-3-ylphenyl)methyl]-6,8-dihydro-5H-imidazo[1,5-a]pyrazine-1-carboxamide;7-(4-bromo-3-chlorobenzoyl)-2-(4-cyclopropyloxyphenyl)-6-methyl-3-oxo-N-[(2-pyrimidin-2-ylphenyl)methyl]-6,8-dihydro-5H-imidazo[1,5-a]pyrazine-1-carboxamide;7-(4-bromo-3-chlorobenzoyl)-6-methyl-3-oxo-2-(4-pyrazol-1-ylphenyl)-N-[(2-pyrimidin-4-ylphenyl)methyl]-6,8-dihydro-5H-imidazo[1,5-a]pyrazine-1-carboxamide;7-(4-bromo-3-cyanobenzoyl)-2-(4-cyclopropyloxyphenyl)-6-methyl-N-[[2-(5-methyl-1,3,4-oxadiazol-2-yl)phenyl]methyl]-3-oxo-6,8-dihydro-5H-imidazo[1,5-a]pyrazine-1-carboxamide (CID 165061385) is N-[[2-(6-aminopyrimidin-4-yl)phenyl]methyl]-7-(4-bromo-3-chlorobenzoyl)-2-(4-cyclopropyloxyphenyl)-6-methyl-3-oxo-6,8-dihydro-5H-imidazo[1,5-a]pyrazine-1-carboxamide;7-(4-bromo-3-chlorobenzoyl)-2-(4-cyclopropyloxyphenyl)-N-[(2-fluoro-6-pyrimidin-4-ylphenyl)methyl]-6-methyl-3-oxo-6,8-dihydro-5H-imidazo[1,5-a]pyrazine-1-carboxamide;7-(4-bromo-3-chlorobenzoyl)-2-(4-cyclopropyloxyphenyl)-6-methyl-N-[[2-(5-methyl-1,3,4-oxadiazol-2-yl)phenyl]methyl]-3-oxo-6,8-dihydro-5H-imidazo[1,5-a]pyrazine-1-carboxamide;7-(4-bromo-3-chlorobenzoyl)-2-(4-cyclopropyloxyphenyl)-6-methyl-N-[[2-(4-methylpyrazol-1-yl)phenyl]methyl]-3-oxo-6,8-dihydro-5H-imidazo[1,5-a]pyrazine-1-carboxamide;7-(4-bromo-3-chlorobenzoyl)-2-(4-cyclopropyloxyphenyl)-6-methyl-3-oxo-N-[(2-pyridazin-3-ylphenyl)methyl]-6,8-dihydro-5H-imidazo[1,5-a]pyrazine-1-carboxamide;7-(4-bromo-3-chlorobenzoyl)-2-(4-cyclopropyloxyphenyl)-6-methyl-3-oxo-N-[(2-pyrimidin-2-ylphenyl)methyl]-6,8-dihydro-5H-imidazo[1,5-a]pyrazine-1-carboxamide;7-(4-bromo-3-chlorobenzoyl)-6-methyl-3-oxo-2-(4-pyrazol-1-ylphenyl)-N-[(2-pyrimidin-4-ylphenyl)methyl]-6,8-dihydro-5H-imidazo[1,5-a]pyrazine-1-carboxamide;7-(4-bromo-3-cyanobenzoyl)-2-(4-cyclopropyloxyphenyl)-6-methyl-N-[[2-(5-methyl-1,3,4-oxadiazol-2-yl)phenyl]methyl]-3-oxo-6,8-dihydro-5H-imidazo[1,5-a]pyrazine-1-carboxamide.
What is the SMILES notation for N-[[2-(6-aminopyrimidin-4-yl)phenyl]methyl]-7-(4-bromo-3-chlorobenzoyl)-2-(4-cyclopropyloxyphenyl)-6-methyl-3-oxo-6,8-dihydro-5H-imidazo[1,5-a]pyrazine-1-carboxamide;7-(4-bromo-3-chlorobenzoyl)-2-(4-cyclopropyloxyphenyl)-N-[(2-fluoro-6-pyrimidin-4-ylphenyl)methyl]-6-methyl-3-oxo-6,8-dihydro-5H-imidazo[1,5-a]pyrazine-1-carboxamide;7-(4-bromo-3-chlorobenzoyl)-2-(4-cyclopropyloxyphenyl)-6-methyl-N-[[2-(5-methyl-1,3,4-oxadiazol-2-yl)phenyl]methyl]-3-oxo-6,8-dihydro-5H-imidazo[1,5-a]pyrazine-1-carboxamide;7-(4-bromo-3-chlorobenzoyl)-2-(4-cyclopropyloxyphenyl)-6-methyl-N-[[2-(4-methylpyrazol-1-yl)phenyl]methyl]-3-oxo-6,8-dihydro-5H-imidazo[1,5-a]pyrazine-1-carboxamide;7-(4-bromo-3-chlorobenzoyl)-2-(4-cyclopropyloxyphenyl)-6-methyl-3-oxo-N-[(2-pyridazin-3-ylphenyl)methyl]-6,8-dihydro-5H-imidazo[1,5-a]pyrazine-1-carboxamide;7-(4-bromo-3-chlorobenzoyl)-2-(4-cyclopropyloxyphenyl)-6-methyl-3-oxo-N-[(2-pyrimidin-2-ylphenyl)methyl]-6,8-dihydro-5H-imidazo[1,5-a]pyrazine-1-carboxamide;7-(4-bromo-3-chlorobenzoyl)-6-methyl-3-oxo-2-(4-pyrazol-1-ylphenyl)-N-[(2-pyrimidin-4-ylphenyl)methyl]-6,8-dihydro-5H-imidazo[1,5-a]pyrazine-1-carboxamide;7-(4-bromo-3-cyanobenzoyl)-2-(4-cyclopropyloxyphenyl)-6-methyl-N-[[2-(5-methyl-1,3,4-oxadiazol-2-yl)phenyl]methyl]-3-oxo-6,8-dihydro-5H-imidazo[1,5-a]pyrazine-1-carboxamide?
The canonical SMILES for N-[[2-(6-aminopyrimidin-4-yl)phenyl]methyl]-7-(4-bromo-3-chlorobenzoyl)-2-(4-cyclopropyloxyphenyl)-6-methyl-3-oxo-6,8-dihydro-5H-imidazo[1,5-a]pyrazine-1-carboxamide;7-(4-bromo-3-chlorobenzoyl)-2-(4-cyclopropyloxyphenyl)-N-[(2-fluoro-6-pyrimidin-4-ylphenyl)methyl]-6-methyl-3-oxo-6,8-dihydro-5H-imidazo[1,5-a]pyrazine-1-carboxamide;7-(4-bromo-3-chlorobenzoyl)-2-(4-cyclopropyloxyphenyl)-6-methyl-N-[[2-(5-methyl-1,3,4-oxadiazol-2-yl)phenyl]methyl]-3-oxo-6,8-dihydro-5H-imidazo[1,5-a]pyrazine-1-carboxamide;7-(4-bromo-3-chlorobenzoyl)-2-(4-cyclopropyloxyphenyl)-6-methyl-N-[[2-(4-methylpyrazol-1-yl)phenyl]methyl]-3-oxo-6,8-dihydro-5H-imidazo[1,5-a]pyrazine-1-carboxamide;7-(4-bromo-3-chlorobenzoyl)-2-(4-cyclopropyloxyphenyl)-6-methyl-3-oxo-N-[(2-pyridazin-3-ylphenyl)methyl]-6,8-dihydro-5H-imidazo[1,5-a]pyrazine-1-carboxamide;7-(4-bromo-3-chlorobenzoyl)-2-(4-cyclopropyloxyphenyl)-6-methyl-3-oxo-N-[(2-pyrimidin-2-ylphenyl)methyl]-6,8-dihydro-5H-imidazo[1,5-a]pyrazine-1-carboxamide;7-(4-bromo-3-chlorobenzoyl)-6-methyl-3-oxo-2-(4-pyrazol-1-ylphenyl)-N-[(2-pyrimidin-4-ylphenyl)methyl]-6,8-dihydro-5H-imidazo[1,5-a]pyrazine-1-carboxamide;7-(4-bromo-3-cyanobenzoyl)-2-(4-cyclopropyloxyphenyl)-6-methyl-N-[[2-(5-methyl-1,3,4-oxadiazol-2-yl)phenyl]methyl]-3-oxo-6,8-dihydro-5H-imidazo[1,5-a]pyrazine-1-carboxamide is CC1Cn2c(c(C(=O)NCc3c(F)cccc3-c3ccncn3)n(-c3ccc(OC4CC4)cc3)c2=O)CN1C(=O)c1ccc(Br)c(Cl)c1.CC1Cn2c(c(C(=O)NCc3ccccc3-c3cc(N)ncn3)n(-c3ccc(OC4CC4)cc3)c2=O)CN1C(=O)c1ccc(Br)c(Cl)c1.CC1Cn2c(c(C(=O)NCc3ccccc3-c3cccnn3)n(-c3ccc(OC4CC4)cc3)c2=O)CN1C(=O)c1ccc(Br)c(Cl)c1.CC1Cn2c(c(C(=O)NCc3ccccc3-c3ccncn3)n(-c3ccc(-n4cccn4)cc3)c2=O)CN1C(=O)c1ccc(Br)c(Cl)c1.CC1Cn2c(c(C(=O)NCc3ccccc3-c3ncccn3)n(-c3ccc(OC4CC4)cc3)c2=O)CN1C(=O)c1ccc(Br)c(Cl)c1.Cc1cnn(-c2ccccc2CNC(=O)c2c3n(c(=O)n2-c2ccc(OC4CC4)cc2)CC(C)N(C(=O)c2ccc(Br)c(Cl)c2)C3)c1.Cc1nnc(-c2ccccc2CNC(=O)c2c3n(c(=O)n2-c2ccc(OC4CC4)cc2)CC(C)N(C(=O)c2ccc(Br)c(C#N)c2)C3)o1.Cc1nnc(-c2ccccc2CNC(=O)c2c3n(c(=O)n2-c2ccc(OC4CC4)cc2)CC(C)N(C(=O)c2ccc(Br)c(Cl)c2)C3)o1.
What is the InChIKey of N-[[2-(6-aminopyrimidin-4-yl)phenyl]methyl]-7-(4-bromo-3-chlorobenzoyl)-2-(4-cyclopropyloxyphenyl)-6-methyl-3-oxo-6,8-dihydro-5H-imidazo[1,5-a]pyrazine-1-carboxamide;7-(4-bromo-3-chlorobenzoyl)-2-(4-cyclopropyloxyphenyl)-N-[(2-fluoro-6-pyrimidin-4-ylphenyl)methyl]-6-methyl-3-oxo-6,8-dihydro-5H-imidazo[1,5-a]pyrazine-1-carboxamide;7-(4-bromo-3-chlorobenzoyl)-2-(4-cyclopropyloxyphenyl)-6-methyl-N-[[2-(5-methyl-1,3,4-oxadiazol-2-yl)phenyl]methyl]-3-oxo-6,8-dihydro-5H-imidazo[1,5-a]pyrazine-1-carboxamide;7-(4-bromo-3-chlorobenzoyl)-2-(4-cyclopropyloxyphenyl)-6-methyl-N-[[2-(4-methylpyrazol-1-yl)phenyl]methyl]-3-oxo-6,8-dihydro-5H-imidazo[1,5-a]pyrazine-1-carboxamide;7-(4-bromo-3-chlorobenzoyl)-2-(4-cyclopropyloxyphenyl)-6-methyl-3-oxo-N-[(2-pyridazin-3-ylphenyl)methyl]-6,8-dihydro-5H-imidazo[1,5-a]pyrazine-1-carboxamide;7-(4-bromo-3-chlorobenzoyl)-2-(4-cyclopropyloxyphenyl)-6-methyl-3-oxo-N-[(2-pyrimidin-2-ylphenyl)methyl]-6,8-dihydro-5H-imidazo[1,5-a]pyrazine-1-carboxamide;7-(4-bromo-3-chlorobenzoyl)-6-methyl-3-oxo-2-(4-pyrazol-1-ylphenyl)-N-[(2-pyrimidin-4-ylphenyl)methyl]-6,8-dihydro-5H-imidazo[1,5-a]pyrazine-1-carboxamide;7-(4-bromo-3-cyanobenzoyl)-2-(4-cyclopropyloxyphenyl)-6-methyl-N-[[2-(5-methyl-1,3,4-oxadiazol-2-yl)phenyl]methyl]-3-oxo-6,8-dihydro-5H-imidazo[1,5-a]pyrazine-1-carboxamide?
The InChIKey is RGNLTYVXGDMTRG-UHFFFAOYSA-N. The full InChI is InChI=1S/C35H29BrClFN6O4.C35H28BrClN8O3.C35H31BrClN7O4.C35H32BrClN6O4.2C35H30BrClN6O4.C35H30BrN7O5.C34H30BrClN6O5/c1-20-17-43-31(18-42(20)34(46)21-5-12-27(36)28(37)15-21)32(44(35(43)47)22-6-8-23(9-7-22)48-24-10-11-24)33(45)40-16-26-25(3-2-4-29(26)38)30-13-14-39-19-41-30;1-22-19-43-31(20-42(22)34(47)23-7-12-28(36)29(37)17-23)32(45(35(43)48)26-10-8-25(9-11-26)44-16-4-14-41-44)33(46)39-18-24-5-2-3-6-27(24)30-13-15-38-21-40-30;1-20-17-43-30(18-42(20)34(46)21-6-13-27(36)28(37)14-21)32(44(35(43)47)23-7-9-24(10-8-23)48-25-11-12-25)33(45)39-16-22-4-2-3-5-26(22)29-15-31(38)41-19-40-29;1-21-16-39-42(18-21)30-6-4-3-5-24(30)17-38-33(44)32-31-20-40(34(45)23-7-14-28(36)29(37)15-23)22(2)19-41(31)35(46)43(32)25-8-10-26(11-9-25)47-27-12-13-27;1-21-19-42-30(20-41(21)34(45)22-7-14-28(36)29(37)17-22)31(43(35(42)46)24-8-10-25(11-9-24)47-26-12-13-26)33(44)40-18-23-5-2-3-6-27(23)32-38-15-4-16-39-32;1-21-19-42-31(20-41(21)34(45)22-8-15-28(36)29(37)17-22)32(43(35(42)46)24-9-11-25(12-10-24)47-26-13-14-26)33(44)38-18-23-5-2-3-6-27(23)30-7-4-16-39-40-30;1-20-18-42-30(19-41(20)34(45)22-7-14-29(36)24(15-22)16-37)31(43(35(42)46)25-8-10-26(11-9-25)48-27-12-13-27)32(44)38-17-23-5-3-4-6-28(23)33-40-39-21(2)47-33;1-19-17-41-29(18-40(19)33(44)21-7-14-27(35)28(36)15-21)30(42(34(41)45)23-8-10-24(11-9-23)47-25-12-13-25)31(43)37-16-22-5-3-4-6-26(22)32-39-38-20(2)46-32/h2-9,12-15,19-20,24H,10-11,16-18H2,1H3,(H,40,45);2-17,21-22H,18-20H2,1H3,(H,39,46);2-10,13-15,19-20,25H,11-12,16-18H2,1H3,(H,39,45)(H2,38,40,41);3-11,14-16,18,22,27H,12-13,17,19-20H2,1-2H3,(H,38,44);2-11,14-17,21,26H,12-13,18-20H2,1H3,(H,40,44);2-12,15-17,21,26H,13-14,18-20H2,1H3,(H,38,44);3-11,14-15,20,27H,12-13,17-19H2,1-2H3,(H,38,44);3-11,14-15,19,25H,12-13,16-18H2,1-2H3,(H,37,43).
What are the key properties of N-[[2-(6-aminopyrimidin-4-yl)phenyl]methyl]-7-(4-bromo-3-chlorobenzoyl)-2-(4-cyclopropyloxyphenyl)-6-methyl-3-oxo-6,8-dihydro-5H-imidazo[1,5-a]pyrazine-1-carboxamide;7-(4-bromo-3-chlorobenzoyl)-2-(4-cyclopropyloxyphenyl)-N-[(2-fluoro-6-pyrimidin-4-ylphenyl)methyl]-6-methyl-3-oxo-6,8-dihydro-5H-imidazo[1,5-a]pyrazine-1-carboxamide;7-(4-bromo-3-chlorobenzoyl)-2-(4-cyclopropyloxyphenyl)-6-methyl-N-[[2-(5-methyl-1,3,4-oxadiazol-2-yl)phenyl]methyl]-3-oxo-6,8-dihydro-5H-imidazo[1,5-a]pyrazine-1-carboxamide;7-(4-bromo-3-chlorobenzoyl)-2-(4-cyclopropyloxyphenyl)-6-methyl-N-[[2-(4-methylpyrazol-1-yl)phenyl]methyl]-3-oxo-6,8-dihydro-5H-imidazo[1,5-a]pyrazine-1-carboxamide;7-(4-bromo-3-chlorobenzoyl)-2-(4-cyclopropyloxyphenyl)-6-methyl-3-oxo-N-[(2-pyridazin-3-ylphenyl)methyl]-6,8-dihydro-5H-imidazo[1,5-a]pyrazine-1-carboxamide;7-(4-bromo-3-chlorobenzoyl)-2-(4-cyclopropyloxyphenyl)-6-methyl-3-oxo-N-[(2-pyrimidin-2-ylphenyl)methyl]-6,8-dihydro-5H-imidazo[1,5-a]pyrazine-1-carboxamide;7-(4-bromo-3-chlorobenzoyl)-6-methyl-3-oxo-2-(4-pyrazol-1-ylphenyl)-N-[(2-pyrimidin-4-ylphenyl)methyl]-6,8-dihydro-5H-imidazo[1,5-a]pyrazine-1-carboxamide;7-(4-bromo-3-cyanobenzoyl)-2-(4-cyclopropyloxyphenyl)-6-methyl-N-[[2-(5-methyl-1,3,4-oxadiazol-2-yl)phenyl]methyl]-3-oxo-6,8-dihydro-5H-imidazo[1,5-a]pyrazine-1-carboxamide?
N-[[2-(6-aminopyrimidin-4-yl)phenyl]methyl]-7-(4-bromo-3-chlorobenzoyl)-2-(4-cyclopropyloxyphenyl)-6-methyl-3-oxo-6,8-dihydro-5H-imidazo[1,5-a]pyrazine-1-carboxamide;7-(4-bromo-3-chlorobenzoyl)-2-(4-cyclopropyloxyphenyl)-N-[(2-fluoro-6-pyrimidin-4-ylphenyl)methyl]-6-methyl-3-oxo-6,8-dihydro-5H-imidazo[1,5-a]pyrazine-1-carboxamide;7-(4-bromo-3-chlorobenzoyl)-2-(4-cyclopropyloxyphenyl)-6-methyl-N-[[2-(5-methyl-1,3,4-oxadiazol-2-yl)phenyl]methyl]-3-oxo-6,8-dihydro-5H-imidazo[1,5-a]pyrazine-1-carboxamide;7-(4-bromo-3-chlorobenzoyl)-2-(4-cyclopropyloxyphenyl)-6-methyl-N-[[2-(4-methylpyrazol-1-yl)phenyl]methyl]-3-oxo-6,8-dihydro-5H-imidazo[1,5-a]pyrazine-1-carboxamide;7-(4-bromo-3-chlorobenzoyl)-2-(4-cyclopropyloxyphenyl)-6-methyl-3-oxo-N-[(2-pyridazin-3-ylphenyl)methyl]-6,8-dihydro-5H-imidazo[1,5-a]pyrazine-1-carboxamide;7-(4-bromo-3-chlorobenzoyl)-2-(4-cyclopropyloxyphenyl)-6-methyl-3-oxo-N-[(2-pyrimidin-2-ylphenyl)methyl]-6,8-dihydro-5H-imidazo[1,5-a]pyrazine-1-carboxamide;7-(4-bromo-3-chlorobenzoyl)-6-methyl-3-oxo-2-(4-pyrazol-1-ylphenyl)-N-[(2-pyrimidin-4-ylphenyl)methyl]-6,8-dihydro-5H-imidazo[1,5-a]pyrazine-1-carboxamide;7-(4-bromo-3-cyanobenzoyl)-2-(4-cyclopropyloxyphenyl)-6-methyl-N-[[2-(5-methyl-1,3,4-oxadiazol-2-yl)phenyl]methyl]-3-oxo-6,8-dihydro-5H-imidazo[1,5-a]pyrazine-1-carboxamide has a molecular weight of 5755.72 g/mol, XLogP of 46.64, 63 rotatable bonds, 9 hydrogen bond donors, and 69 hydrogen bond acceptors.
Where does this data come from?
All data for N-[[2-(6-aminopyrimidin-4-yl)phenyl]methyl]-7-(4-bromo-3-chlorobenzoyl)-2-(4-cyclopropyloxyphenyl)-6-methyl-3-oxo-6,8-dihydro-5H-imidazo[1,5-a]pyrazine-1-carboxamide;7-(4-bromo-3-chlorobenzoyl)-2-(4-cyclopropyloxyphenyl)-N-[(2-fluoro-6-pyrimidin-4-ylphenyl)methyl]-6-methyl-3-oxo-6,8-dihydro-5H-imidazo[1,5-a]pyrazine-1-carboxamide;7-(4-bromo-3-chlorobenzoyl)-2-(4-cyclopropyloxyphenyl)-6-methyl-N-[[2-(5-methyl-1,3,4-oxadiazol-2-yl)phenyl]methyl]-3-oxo-6,8-dihydro-5H-imidazo[1,5-a]pyrazine-1-carboxamide;7-(4-bromo-3-chlorobenzoyl)-2-(4-cyclopropyloxyphenyl)-6-methyl-N-[[2-(4-methylpyrazol-1-yl)phenyl]methyl]-3-oxo-6,8-dihydro-5H-imidazo[1,5-a]pyrazine-1-carboxamide;7-(4-bromo-3-chlorobenzoyl)-2-(4-cyclopropyloxyphenyl)-6-methyl-3-oxo-N-[(2-pyridazin-3-ylphenyl)methyl]-6,8-dihydro-5H-imidazo[1,5-a]pyrazine-1-carboxamide;7-(4-bromo-3-chlorobenzoyl)-2-(4-cyclopropyloxyphenyl)-6-methyl-3-oxo-N-[(2-pyrimidin-2-ylphenyl)methyl]-6,8-dihydro-5H-imidazo[1,5-a]pyrazine-1-carboxamide;7-(4-bromo-3-chlorobenzoyl)-6-methyl-3-oxo-2-(4-pyrazol-1-ylphenyl)-N-[(2-pyrimidin-4-ylphenyl)methyl]-6,8-dihydro-5H-imidazo[1,5-a]pyrazine-1-carboxamide;7-(4-bromo-3-cyanobenzoyl)-2-(4-cyclopropyloxyphenyl)-6-methyl-N-[[2-(5-methyl-1,3,4-oxadiazol-2-yl)phenyl]methyl]-3-oxo-6,8-dihydro-5H-imidazo[1,5-a]pyrazine-1-carboxamide is sourced from PubChem (CID 165061385), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).