6-bromo-1H-1,5-naphthyridin-2-one;6-bromo-1-(2-trimethylsilylethoxymethyl)-1,5-naphthyridin-2-one;tert-butyl 3-methyl-6-[6-oxo-5-(2-trimethylsilylethoxymethyl)-1,5-naphthyridin-2-yl]-3,4-dihydro-2H-pyridine-1-carboxylate;bis(tert-butyl 3-methyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3,4-dihydro-2H-pyridine-1-carboxylate);tert-butyl 3-methyl-6-(trifluoromethylsulfonyloxy)-3,4-dihydro-2H-pyridine-1-carboxylate;ethyl 3-(3-amino-6-bromo-2-pyridinyl)prop-2-enoate;6-(5-methylpiperidin-2-yl)-1-(2-trimethylsilylethoxymethyl)-1,5-naphthyridin-2-one;6-(3-methyl-1,2,3,4-tetrahydropyridin-6-yl)-1-(2-trimethylsilylethoxymethyl)-1,5-naphthyridin-2-one

C143H210B2Br3F3N18O26SSi4 — CID 165073163

About 6-bromo-1H-1,5-naphthyridin-2-one;6-bromo-1-(2-trimethylsilylethoxymethyl)-1,5-naphthyridin-2-one;tert-butyl 3-methyl-6-[6-oxo-5-(2-trimethylsilylethoxymethyl)-1,5-naphthyridin-2-yl]-3,4-dihydro-2H-pyridine-1-carboxylate;bis(tert-butyl 3-methyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3,4-dihydro-2H-pyridine-1-carboxylate);tert-butyl 3-methyl-6-(trifluoromethylsulfonyloxy)-3,4-dihydro-2H-pyridine-1-carboxylate;ethyl 3-(3-amino-6-bromo-2-pyridinyl)prop-2-enoate;6-(5-methylpiperidin-2-yl)-1-(2-trimethylsilylethoxymethyl)-1,5-naphthyridin-2-one;6-(3-methyl-1,2,3,4-tetrahydropyridin-6-yl)-1-(2-trimethylsilylethoxymethyl)-1,5-naphthyridin-2-one

6-bromo-1H-1,5-naphthyridin-2-one;6-bromo-1-(2-trimethylsilylethoxymethyl)-1,5-naphthyridin-2-one;tert-butyl 3-methyl-6-[6-oxo-5-(2-trimethylsilylethoxymethyl)-1,5-naphthyridin-2-yl]-3,4-dihydro-2H-pyridine-1-carboxylate;bis(tert-butyl 3-methyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3,4-dihydro-2H-pyridine-1-carboxylate);tert-butyl 3-methyl-6-(trifluoromethylsulfonyloxy)-3,4-dihydro-2H-pyridine-1-carboxylate;ethyl 3-(3-amino-6-bromo-2-pyridinyl)prop-2-enoate;6-(5-methylpiperidin-2-yl)-1-(2-trimethylsilylethoxymethyl)-1,5-naphthyridin-2-one;6-(3-methyl-1,2,3,4-tetrahydropyridin-6-yl)-1-(2-trimethylsilylethoxymethyl)-1,5-naphthyridin-2-one (PubChem CID 165073163) has the molecular formula C143H210B2Br3F3N18O26SSi4 and a molecular weight of 3060.09 g/mol. Its IUPAC name is 6-bromo-1H-1,5-naphthyridin-2-one;6-bromo-1-(2-trimethylsilylethoxymethyl)-1,5-naphthyridin-2-one;tert-butyl 3-methyl-6-[6-oxo-5-(2-trimethylsilylethoxymethyl)-1,5-naphthyridin-2-yl]-3,4-dihydro-2H-pyridine-1-carboxylate;bis(tert-butyl 3-methyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3,4-dihydro-2H-pyridine-1-carboxylate);tert-butyl 3-methyl-6-(trifluoromethylsulfonyloxy)-3,4-dihydro-2H-pyridine-1-carboxylate;ethyl 3-(3-amino-6-bromo-2-pyridinyl)prop-2-enoate;6-(5-methylpiperidin-2-yl)-1-(2-trimethylsilylethoxymethyl)-1,5-naphthyridin-2-one;6-(3-methyl-1,2,3,4-tetrahydropyridin-6-yl)-1-(2-trimethylsilylethoxymethyl)-1,5-naphthyridin-2-one.

Molecular Properties

• Compound Name: 6-bromo-1H-1,5-naphthyridin-2-one;6-bromo-1-(2-trimethylsilylethoxymethyl)-1,5-naphthyridin-2-one;tert-butyl 3-methyl-6-[6-oxo-5-(2-trimethylsilylethoxymethyl)-1,5-naphthyridin-2-yl]-3,4-dihydro-2H-pyridine-1-carboxylate;bis(tert-butyl 3-methyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3,4-dihydro-2H-pyridine-1-carboxylate);tert-butyl 3-methyl-6-(trifluoromethylsulfonyloxy)-3,4-dihydro-2H-pyridine-1-carboxylate;ethyl 3-(3-amino-6-bromo-2-pyridinyl)prop-2-enoate;6-(5-methylpiperidin-2-yl)-1-(2-trimethylsilylethoxymethyl)-1,5-naphthyridin-2-one;6-(3-methyl-1,2,3,4-tetrahydropyridin-6-yl)-1-(2-trimethylsilylethoxymethyl)-1,5-naphthyridin-2-one
• PubChem CID: 165073163
• Molecular Formula: C143H210B2Br3F3N18O26SSi4
• Molecular Weight: 3060.09 g/mol
• Exact Mass: 3055.21
• IUPAC Name: 6-bromo-1H-1,5-naphthyridin-2-one;6-bromo-1-(2-trimethylsilylethoxymethyl)-1,5-naphthyridin-2-one;tert-butyl 3-methyl-6-[6-oxo-5-(2-trimethylsilylethoxymethyl)-1,5-naphthyridin-2-yl]-3,4-dihydro-2H-pyridine-1-carboxylate;bis(tert-butyl 3-methyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3,4-dihydro-2H-pyridine-1-carboxylate);tert-butyl 3-methyl-6-(trifluoromethylsulfonyloxy)-3,4-dihydro-2H-pyridine-1-carboxylate;ethyl 3-(3-amino-6-bromo-2-pyridinyl)prop-2-enoate;6-(5-methylpiperidin-2-yl)-1-(2-trimethylsilylethoxymethyl)-1,5-naphthyridin-2-one;6-(3-methyl-1,2,3,4-tetrahydropyridin-6-yl)-1-(2-trimethylsilylethoxymethyl)-1,5-naphthyridin-2-one
• SMILES: CC1CC=C(B2OC(C)(C)C(C)(C)O2)N(C(=O)OC(C)(C)C)C1.CC1CC=C(B2OC(C)(C)C(C)(C)O2)N(C(=O)OC(C)(C)C)C1.CC1CC=C(OS(=O)(=O)C(F)(F)F)N(C(=O)OC(C)(C)C)C1.CC1CC=C(c2ccc3c(ccc(=O)n3COCC[Si](C)(C)C)n2)N(C(=O)OC(C)(C)C)C1.CC1CC=C(c2ccc3c(ccc(=O)n3COCC[Si](C)(C)C)n2)NC1.CC1CCC(c2ccc3c(ccc(=O)n3COCC[Si](C)(C)C)n2)NC1.CCOC(=O)C=Cc1nc(Br)ccc1N.C[Si](C)(C)CCOCn1c(=O)ccc2nc(Br)ccc21.O=c1ccc2nc(Br)ccc2[nH]1
• InChI: InChI=1S/C25H37N3O4Si.C20H31N3O2Si.C20H29N3O2Si.2C17H30BNO4.C14H19BrN2O2Si.C12H18F3NO5S.C10H11BrN2O2.C8H5BrN2O/c1-18-8-11-21(27(16-18)24(30)32-25(2,3)4)19-9-12-22-20(26-19)10-13-23(29)28(22)17-31-14-15-33(5,6)7;2*1-15-5-6-16(21-13-15)17-7-9-19-18(22-17)8-10-20(24)23(19)14-25-11-12-26(2,3)4;2*1-12-9-10-13(18-22-16(5,6)17(7,8)23-18)19(11-12)14(20)21-15(2,3)4;1-20(2,3)9-8-19-10-17-12-5-6-13(15)16-11(12)4-7-14(17)18;1-8-5-6-9(21-22(18,19)12(13,14)15)16(7-8)10(17)20-11(2,3)4;1-2-15-10(14)6-4-8-7(12)3-5-9(11)13-8;9-7-3-1-6-5(10-7)2-4-8(12)11-6/h9-13,18H,8,14-17H2,1-7H3;7-10,15-16,21H,5-6,11-14H2,1-4H3;6-10,15,21H,5,11-14H2,1-4H3;2*10,12H,9,11H2,1-8H3;4-7H,8-10H2,1-3H3;6,8H,5,7H2,1-4H3;3-6H,2,12H2,1H3;1-4H,(H,11,12)
• InChIKey: TWEZFJRTPISISI-UHFFFAOYSA-N
• XLogP: 30.46
• TPSA: 509.95 Ų
• H-Bond Donors: 4
• H-Bond Acceptors: 39
• Rotatable Bonds: 30
• Heavy Atoms: 200
• Complexity: —

Lipinski Rule of Five

3 violations

Rule	Value
MW ≤ 500	3060.09
LogP ≤ 5	30.46
H-Bond Donors ≤ 5	4
H-Bond Acceptors ≤ 10	39

Computed Properties (RDKit)

• Structural Alerts: {'alert_name': '>_2_ester_groups', 'substructure': 'N/A'}, {'alert_name': '2-halo_pyridine', 'substructure': 'N/A'}, {'alert_name': 'Aliphatic_long_chain', 'substructure': 'N/A'}, {'alert_name': 'heavy_metal', 'substructure': 'N/A'}, {'alert_name': 'Michael_acceptor_1', 'substructure': 'N/A'}

Frequently Asked Questions

What is the IUPAC name of 6-bromo-1H-1,5-naphthyridin-2-one;6-bromo-1-(2-trimethylsilylethoxymethyl)-1,5-naphthyridin-2-one;tert-butyl 3-methyl-6-[6-oxo-5-(2-trimethylsilylethoxymethyl)-1,5-naphthyridin-2-yl]-3,4-dihydro-2H-pyridine-1-carboxylate;bis(tert-butyl 3-methyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3,4-dihydro-2H-pyridine-1-carboxylate);tert-butyl 3-methyl-6-(trifluoromethylsulfonyloxy)-3,4-dihydro-2H-pyridine-1-carboxylate;ethyl 3-(3-amino-6-bromo-2-pyridinyl)prop-2-enoate;6-(5-methylpiperidin-2-yl)-1-(2-trimethylsilylethoxymethyl)-1,5-naphthyridin-2-one;6-(3-methyl-1,2,3,4-tetrahydropyridin-6-yl)-1-(2-trimethylsilylethoxymethyl)-1,5-naphthyridin-2-one?

The IUPAC name of 6-bromo-1H-1,5-naphthyridin-2-one;6-bromo-1-(2-trimethylsilylethoxymethyl)-1,5-naphthyridin-2-one;tert-butyl 3-methyl-6-[6-oxo-5-(2-trimethylsilylethoxymethyl)-1,5-naphthyridin-2-yl]-3,4-dihydro-2H-pyridine-1-carboxylate;bis(tert-butyl 3-methyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3,4-dihydro-2H-pyridine-1-carboxylate);tert-butyl 3-methyl-6-(trifluoromethylsulfonyloxy)-3,4-dihydro-2H-pyridine-1-carboxylate;ethyl 3-(3-amino-6-bromo-2-pyridinyl)prop-2-enoate;6-(5-methylpiperidin-2-yl)-1-(2-trimethylsilylethoxymethyl)-1,5-naphthyridin-2-one;6-(3-methyl-1,2,3,4-tetrahydropyridin-6-yl)-1-(2-trimethylsilylethoxymethyl)-1,5-naphthyridin-2-one (CID 165073163) is 6-bromo-1H-1,5-naphthyridin-2-one;6-bromo-1-(2-trimethylsilylethoxymethyl)-1,5-naphthyridin-2-one;tert-butyl 3-methyl-6-[6-oxo-5-(2-trimethylsilylethoxymethyl)-1,5-naphthyridin-2-yl]-3,4-dihydro-2H-pyridine-1-carboxylate;bis(tert-butyl 3-methyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3,4-dihydro-2H-pyridine-1-carboxylate);tert-butyl 3-methyl-6-(trifluoromethylsulfonyloxy)-3,4-dihydro-2H-pyridine-1-carboxylate;ethyl 3-(3-amino-6-bromo-2-pyridinyl)prop-2-enoate;6-(5-methylpiperidin-2-yl)-1-(2-trimethylsilylethoxymethyl)-1,5-naphthyridin-2-one;6-(3-methyl-1,2,3,4-tetrahydropyridin-6-yl)-1-(2-trimethylsilylethoxymethyl)-1,5-naphthyridin-2-one.

What is the SMILES notation for 6-bromo-1H-1,5-naphthyridin-2-one;6-bromo-1-(2-trimethylsilylethoxymethyl)-1,5-naphthyridin-2-one;tert-butyl 3-methyl-6-[6-oxo-5-(2-trimethylsilylethoxymethyl)-1,5-naphthyridin-2-yl]-3,4-dihydro-2H-pyridine-1-carboxylate;bis(tert-butyl 3-methyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3,4-dihydro-2H-pyridine-1-carboxylate);tert-butyl 3-methyl-6-(trifluoromethylsulfonyloxy)-3,4-dihydro-2H-pyridine-1-carboxylate;ethyl 3-(3-amino-6-bromo-2-pyridinyl)prop-2-enoate;6-(5-methylpiperidin-2-yl)-1-(2-trimethylsilylethoxymethyl)-1,5-naphthyridin-2-one;6-(3-methyl-1,2,3,4-tetrahydropyridin-6-yl)-1-(2-trimethylsilylethoxymethyl)-1,5-naphthyridin-2-one?

The canonical SMILES for 6-bromo-1H-1,5-naphthyridin-2-one;6-bromo-1-(2-trimethylsilylethoxymethyl)-1,5-naphthyridin-2-one;tert-butyl 3-methyl-6-[6-oxo-5-(2-trimethylsilylethoxymethyl)-1,5-naphthyridin-2-yl]-3,4-dihydro-2H-pyridine-1-carboxylate;bis(tert-butyl 3-methyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3,4-dihydro-2H-pyridine-1-carboxylate);tert-butyl 3-methyl-6-(trifluoromethylsulfonyloxy)-3,4-dihydro-2H-pyridine-1-carboxylate;ethyl 3-(3-amino-6-bromo-2-pyridinyl)prop-2-enoate;6-(5-methylpiperidin-2-yl)-1-(2-trimethylsilylethoxymethyl)-1,5-naphthyridin-2-one;6-(3-methyl-1,2,3,4-tetrahydropyridin-6-yl)-1-(2-trimethylsilylethoxymethyl)-1,5-naphthyridin-2-one is CC1CC=C(B2OC(C)(C)C(C)(C)O2)N(C(=O)OC(C)(C)C)C1.CC1CC=C(B2OC(C)(C)C(C)(C)O2)N(C(=O)OC(C)(C)C)C1.CC1CC=C(OS(=O)(=O)C(F)(F)F)N(C(=O)OC(C)(C)C)C1.CC1CC=C(c2ccc3c(ccc(=O)n3COCC[Si](C)(C)C)n2)N(C(=O)OC(C)(C)C)C1.CC1CC=C(c2ccc3c(ccc(=O)n3COCC[Si](C)(C)C)n2)NC1.CC1CCC(c2ccc3c(ccc(=O)n3COCC[Si](C)(C)C)n2)NC1.CCOC(=O)C=Cc1nc(Br)ccc1N.C[Si](C)(C)CCOCn1c(=O)ccc2nc(Br)ccc21.O=c1ccc2nc(Br)ccc2[nH]1.

What is the InChIKey of 6-bromo-1H-1,5-naphthyridin-2-one;6-bromo-1-(2-trimethylsilylethoxymethyl)-1,5-naphthyridin-2-one;tert-butyl 3-methyl-6-[6-oxo-5-(2-trimethylsilylethoxymethyl)-1,5-naphthyridin-2-yl]-3,4-dihydro-2H-pyridine-1-carboxylate;bis(tert-butyl 3-methyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3,4-dihydro-2H-pyridine-1-carboxylate);tert-butyl 3-methyl-6-(trifluoromethylsulfonyloxy)-3,4-dihydro-2H-pyridine-1-carboxylate;ethyl 3-(3-amino-6-bromo-2-pyridinyl)prop-2-enoate;6-(5-methylpiperidin-2-yl)-1-(2-trimethylsilylethoxymethyl)-1,5-naphthyridin-2-one;6-(3-methyl-1,2,3,4-tetrahydropyridin-6-yl)-1-(2-trimethylsilylethoxymethyl)-1,5-naphthyridin-2-one?

The InChIKey is TWEZFJRTPISISI-UHFFFAOYSA-N. The full InChI is InChI=1S/C25H37N3O4Si.C20H31N3O2Si.C20H29N3O2Si.2C17H30BNO4.C14H19BrN2O2Si.C12H18F3NO5S.C10H11BrN2O2.C8H5BrN2O/c1-18-8-11-21(27(16-18)24(30)32-25(2,3)4)19-9-12-22-20(26-19)10-13-23(29)28(22)17-31-14-15-33(5,6)7;2*1-15-5-6-16(21-13-15)17-7-9-19-18(22-17)8-10-20(24)23(19)14-25-11-12-26(2,3)4;2*1-12-9-10-13(18-22-16(5,6)17(7,8)23-18)19(11-12)14(20)21-15(2,3)4;1-20(2,3)9-8-19-10-17-12-5-6-13(15)16-11(12)4-7-14(17)18;1-8-5-6-9(21-22(18,19)12(13,14)15)16(7-8)10(17)20-11(2,3)4;1-2-15-10(14)6-4-8-7(12)3-5-9(11)13-8;9-7-3-1-6-5(10-7)2-4-8(12)11-6/h9-13,18H,8,14-17H2,1-7H3;7-10,15-16,21H,5-6,11-14H2,1-4H3;6-10,15,21H,5,11-14H2,1-4H3;2*10,12H,9,11H2,1-8H3;4-7H,8-10H2,1-3H3;6,8H,5,7H2,1-4H3;3-6H,2,12H2,1H3;1-4H,(H,11,12).

What are the key properties of 6-bromo-1H-1,5-naphthyridin-2-one;6-bromo-1-(2-trimethylsilylethoxymethyl)-1,5-naphthyridin-2-one;tert-butyl 3-methyl-6-[6-oxo-5-(2-trimethylsilylethoxymethyl)-1,5-naphthyridin-2-yl]-3,4-dihydro-2H-pyridine-1-carboxylate;bis(tert-butyl 3-methyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3,4-dihydro-2H-pyridine-1-carboxylate);tert-butyl 3-methyl-6-(trifluoromethylsulfonyloxy)-3,4-dihydro-2H-pyridine-1-carboxylate;ethyl 3-(3-amino-6-bromo-2-pyridinyl)prop-2-enoate;6-(5-methylpiperidin-2-yl)-1-(2-trimethylsilylethoxymethyl)-1,5-naphthyridin-2-one;6-(3-methyl-1,2,3,4-tetrahydropyridin-6-yl)-1-(2-trimethylsilylethoxymethyl)-1,5-naphthyridin-2-one?

6-bromo-1H-1,5-naphthyridin-2-one;6-bromo-1-(2-trimethylsilylethoxymethyl)-1,5-naphthyridin-2-one;tert-butyl 3-methyl-6-[6-oxo-5-(2-trimethylsilylethoxymethyl)-1,5-naphthyridin-2-yl]-3,4-dihydro-2H-pyridine-1-carboxylate;bis(tert-butyl 3-methyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3,4-dihydro-2H-pyridine-1-carboxylate);tert-butyl 3-methyl-6-(trifluoromethylsulfonyloxy)-3,4-dihydro-2H-pyridine-1-carboxylate;ethyl 3-(3-amino-6-bromo-2-pyridinyl)prop-2-enoate;6-(5-methylpiperidin-2-yl)-1-(2-trimethylsilylethoxymethyl)-1,5-naphthyridin-2-one;6-(3-methyl-1,2,3,4-tetrahydropyridin-6-yl)-1-(2-trimethylsilylethoxymethyl)-1,5-naphthyridin-2-one has a molecular weight of 3060.09 g/mol, XLogP of 30.46, 30 rotatable bonds, 4 hydrogen bond donors, and 39 hydrogen bond acceptors.

Where does this data come from?

All data for 6-bromo-1H-1,5-naphthyridin-2-one;6-bromo-1-(2-trimethylsilylethoxymethyl)-1,5-naphthyridin-2-one;tert-butyl 3-methyl-6-[6-oxo-5-(2-trimethylsilylethoxymethyl)-1,5-naphthyridin-2-yl]-3,4-dihydro-2H-pyridine-1-carboxylate;bis(tert-butyl 3-methyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3,4-dihydro-2H-pyridine-1-carboxylate);tert-butyl 3-methyl-6-(trifluoromethylsulfonyloxy)-3,4-dihydro-2H-pyridine-1-carboxylate;ethyl 3-(3-amino-6-bromo-2-pyridinyl)prop-2-enoate;6-(5-methylpiperidin-2-yl)-1-(2-trimethylsilylethoxymethyl)-1,5-naphthyridin-2-one;6-(3-methyl-1,2,3,4-tetrahydropyridin-6-yl)-1-(2-trimethylsilylethoxymethyl)-1,5-naphthyridin-2-one is sourced from PubChem (CID 165073163), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).