(1S)-1'-[7-amino-8-(2-amino-3-chloro-4-pyridinyl)imidazo[1,2-a]pyridin-5-yl]spiro[1,3-dihydroindene-2,4'-piperidine]-1-amine;(3R)-1'-[7-amino-8-(2-amino-3-chloro-4-pyridinyl)imidazo[1,2-a]pyridin-5-yl]spiro[3H-furo[2,3-b]pyridine-2,4'-piperidine]-3-amine;[8-(2-amino-3-chloro-4-pyridinyl)-5-[(5S)-5-aminospiro[5,7-dihydrocyclopenta[b]pyridine-6,4'-piperidine]-1'-yl]imidazo[1,2-a]pyridin-7-yl]methanol;8-(2-amino-3-chloro-4-pyridinyl)-5-[(1S)-1-aminospiro[1,3-dihydroindene-2,4'-piperidine]-1'-yl]imidazo[1,2-a]pyridine-7-sulfonamide;(1S)-1'-[8-(2-amino-3-chloro-4-pyridinyl)-7-methylimidazo[1,2-a]pyridin-5-yl]spiro[1,3-dihydroindene-2,4'-piperidine]-1-amine

C124H128Cl5N35O4S — CID 165077491

About (1S)-1'-[7-amino-8-(2-amino-3-chloro-4-pyridinyl)imidazo[1,2-a]pyridin-5-yl]spiro[1,3-dihydroindene-2,4'-piperidine]-1-amine;(3R)-1'-[7-amino-8-(2-amino-3-chloro-4-pyridinyl)imidazo[1,2-a]pyridin-5-yl]spiro[3H-furo[2,3-b]pyridine-2,4'-piperidine]-3-amine;[8-(2-amino-3-chloro-4-pyridinyl)-5-[(5S)-5-aminospiro[5,7-dihydrocyclopenta[b]pyridine-6,4'-piperidine]-1'-yl]imidazo[1,2-a]pyridin-7-yl]methanol;8-(2-amino-3-chloro-4-pyridinyl)-5-[(1S)-1-aminospiro[1,3-dihydroindene-2,4'-piperidine]-1'-yl]imidazo[1,2-a]pyridine-7-sulfonamide;(1S)-1'-[8-(2-amino-3-chloro-4-pyridinyl)-7-methylimidazo[1,2-a]pyridin-5-yl]spiro[1,3-dihydroindene-2,4'-piperidine]-1-amine

(1S)-1'-[7-amino-8-(2-amino-3-chloro-4-pyridinyl)imidazo[1,2-a]pyridin-5-yl]spiro[1,3-dihydroindene-2,4'-piperidine]-1-amine;(3R)-1'-[7-amino-8-(2-amino-3-chloro-4-pyridinyl)imidazo[1,2-a]pyridin-5-yl]spiro[3H-furo[2,3-b]pyridine-2,4'-piperidine]-3-amine;[8-(2-amino-3-chloro-4-pyridinyl)-5-[(5S)-5-aminospiro[5,7-dihydrocyclopenta[b]pyridine-6,4'-piperidine]-1'-yl]imidazo[1,2-a]pyridin-7-yl]methanol;8-(2-amino-3-chloro-4-pyridinyl)-5-[(1S)-1-aminospiro[1,3-dihydroindene-2,4'-piperidine]-1'-yl]imidazo[1,2-a]pyridine-7-sulfonamide;(1S)-1'-[8-(2-amino-3-chloro-4-pyridinyl)-7-methylimidazo[1,2-a]pyridin-5-yl]spiro[1,3-dihydroindene-2,4'-piperidine]-1-amine (PubChem CID 165077491) has the molecular formula C124H128Cl5N35O4S and a molecular weight of 2381.96 g/mol. Its IUPAC name is (1S)-1'-[7-amino-8-(2-amino-3-chloro-4-pyridinyl)imidazo[1,2-a]pyridin-5-yl]spiro[1,3-dihydroindene-2,4'-piperidine]-1-amine;(3R)-1'-[7-amino-8-(2-amino-3-chloro-4-pyridinyl)imidazo[1,2-a]pyridin-5-yl]spiro[3H-furo[2,3-b]pyridine-2,4'-piperidine]-3-amine;[8-(2-amino-3-chloro-4-pyridinyl)-5-[(5S)-5-aminospiro[5,7-dihydrocyclopenta[b]pyridine-6,4'-piperidine]-1'-yl]imidazo[1,2-a]pyridin-7-yl]methanol;8-(2-amino-3-chloro-4-pyridinyl)-5-[(1S)-1-aminospiro[1,3-dihydroindene-2,4'-piperidine]-1'-yl]imidazo[1,2-a]pyridine-7-sulfonamide;(1S)-1'-[8-(2-amino-3-chloro-4-pyridinyl)-7-methylimidazo[1,2-a]pyridin-5-yl]spiro[1,3-dihydroindene-2,4'-piperidine]-1-amine.

Molecular Properties

• Compound Name: (1S)-1'-[7-amino-8-(2-amino-3-chloro-4-pyridinyl)imidazo[1,2-a]pyridin-5-yl]spiro[1,3-dihydroindene-2,4'-piperidine]-1-amine;(3R)-1'-[7-amino-8-(2-amino-3-chloro-4-pyridinyl)imidazo[1,2-a]pyridin-5-yl]spiro[3H-furo[2,3-b]pyridine-2,4'-piperidine]-3-amine;[8-(2-amino-3-chloro-4-pyridinyl)-5-[(5S)-5-aminospiro[5,7-dihydrocyclopenta[b]pyridine-6,4'-piperidine]-1'-yl]imidazo[1,2-a]pyridin-7-yl]methanol;8-(2-amino-3-chloro-4-pyridinyl)-5-[(1S)-1-aminospiro[1,3-dihydroindene-2,4'-piperidine]-1'-yl]imidazo[1,2-a]pyridine-7-sulfonamide;(1S)-1'-[8-(2-amino-3-chloro-4-pyridinyl)-7-methylimidazo[1,2-a]pyridin-5-yl]spiro[1,3-dihydroindene-2,4'-piperidine]-1-amine
• PubChem CID: 165077491
• Molecular Formula: C124H128Cl5N35O4S
• Molecular Weight: 2381.96 g/mol
• Exact Mass: 2377.91
• IUPAC Name: (1S)-1'-[7-amino-8-(2-amino-3-chloro-4-pyridinyl)imidazo[1,2-a]pyridin-5-yl]spiro[1,3-dihydroindene-2,4'-piperidine]-1-amine;(3R)-1'-[7-amino-8-(2-amino-3-chloro-4-pyridinyl)imidazo[1,2-a]pyridin-5-yl]spiro[3H-furo[2,3-b]pyridine-2,4'-piperidine]-3-amine;[8-(2-amino-3-chloro-4-pyridinyl)-5-[(5S)-5-aminospiro[5,7-dihydrocyclopenta[b]pyridine-6,4'-piperidine]-1'-yl]imidazo[1,2-a]pyridin-7-yl]methanol;8-(2-amino-3-chloro-4-pyridinyl)-5-[(1S)-1-aminospiro[1,3-dihydroindene-2,4'-piperidine]-1'-yl]imidazo[1,2-a]pyridine-7-sulfonamide;(1S)-1'-[8-(2-amino-3-chloro-4-pyridinyl)-7-methylimidazo[1,2-a]pyridin-5-yl]spiro[1,3-dihydroindene-2,4'-piperidine]-1-amine
• SMILES: Cc1cc(N2CCC3(CC2)Cc2ccccc2[C@H]3N)n2ccnc2c1-c1ccnc(N)c1Cl.Nc1cc(N2CCC3(CC2)Cc2ccccc2[C@H]3N)n2ccnc2c1-c1ccnc(N)c1Cl.Nc1cc(N2CCC3(CC2)Oc2ncccc2[C@H]3N)n2ccnc2c1-c1ccnc(N)c1Cl.Nc1nccc(-c2c(CO)cc(N3CCC4(CC3)Cc3ncccc3[C@H]4N)n3ccnc23)c1Cl.Nc1nccc(-c2c(S(N)(=O)=O)cc(N3CCC4(CC3)Cc3ccccc3[C@H]4N)n3ccnc23)c1Cl
• InChI: InChI=1S/C26H27ClN6.C25H26ClN7O2S.C25H26ClN7O.C25H26ClN7.C23H23ClN8O/c1-16-14-20(33-13-10-31-25(33)21(16)19-6-9-30-24(29)22(19)27)32-11-7-26(8-12-32)15-17-4-2-3-5-18(17)23(26)28;26-21-17(5-8-30-23(21)28)20-18(36(29,34)35)13-19(33-12-9-31-24(20)33)32-10-6-25(7-11-32)14-15-3-1-2-4-16(15)22(25)27;26-21-17(3-7-30-23(21)28)20-15(14-34)12-19(33-11-8-31-24(20)33)32-9-4-25(5-10-32)13-18-16(22(25)27)2-1-6-29-18;26-21-17(5-8-30-23(21)29)20-18(27)13-19(33-12-9-31-24(20)33)32-10-6-25(7-11-32)14-15-3-1-2-4-16(15)22(25)28;24-18-13(3-7-28-20(18)27)17-15(25)12-16(32-11-8-29-21(17)32)31-9-4-23(5-10-31)19(26)14-2-1-6-30-22(14)33-23/h2-6,9-10,13-14,23H,7-8,11-12,15,28H2,1H3,(H2,29,30);1-5,8-9,12-13,22H,6-7,10-11,14,27H2,(H2,28,30)(H2,29,34,35);1-3,6-8,11-12,22,34H,4-5,9-10,13-14,27H2,(H2,28,30);1-5,8-9,12-13,22H,6-7,10-11,14,27-28H2,(H2,29,30);1-3,6-8,11-12,19H,4-5,9-10,25-26H2,(H2,27,28)/t23-;3*22-;19-/m11111/s1
• InChIKey: UODJOEWMUNEDPY-HKZJWQGLSA-N
• XLogP: 18.36
• TPSA: 594.79 Ų
• H-Bond Donors: 14
• H-Bond Acceptors: 38
• Rotatable Bonds: 12
• Heavy Atoms: 169
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2381.96
LogP ≤ 5	18.36
H-Bond Donors ≤ 5	14
H-Bond Acceptors ≤ 10	38

Frequently Asked Questions

What is the IUPAC name of (1S)-1'-[7-amino-8-(2-amino-3-chloro-4-pyridinyl)imidazo[1,2-a]pyridin-5-yl]spiro[1,3-dihydroindene-2,4'-piperidine]-1-amine;(3R)-1'-[7-amino-8-(2-amino-3-chloro-4-pyridinyl)imidazo[1,2-a]pyridin-5-yl]spiro[3H-furo[2,3-b]pyridine-2,4'-piperidine]-3-amine;[8-(2-amino-3-chloro-4-pyridinyl)-5-[(5S)-5-aminospiro[5,7-dihydrocyclopenta[b]pyridine-6,4'-piperidine]-1'-yl]imidazo[1,2-a]pyridin-7-yl]methanol;8-(2-amino-3-chloro-4-pyridinyl)-5-[(1S)-1-aminospiro[1,3-dihydroindene-2,4'-piperidine]-1'-yl]imidazo[1,2-a]pyridine-7-sulfonamide;(1S)-1'-[8-(2-amino-3-chloro-4-pyridinyl)-7-methylimidazo[1,2-a]pyridin-5-yl]spiro[1,3-dihydroindene-2,4'-piperidine]-1-amine?

The IUPAC name of (1S)-1'-[7-amino-8-(2-amino-3-chloro-4-pyridinyl)imidazo[1,2-a]pyridin-5-yl]spiro[1,3-dihydroindene-2,4'-piperidine]-1-amine;(3R)-1'-[7-amino-8-(2-amino-3-chloro-4-pyridinyl)imidazo[1,2-a]pyridin-5-yl]spiro[3H-furo[2,3-b]pyridine-2,4'-piperidine]-3-amine;[8-(2-amino-3-chloro-4-pyridinyl)-5-[(5S)-5-aminospiro[5,7-dihydrocyclopenta[b]pyridine-6,4'-piperidine]-1'-yl]imidazo[1,2-a]pyridin-7-yl]methanol;8-(2-amino-3-chloro-4-pyridinyl)-5-[(1S)-1-aminospiro[1,3-dihydroindene-2,4'-piperidine]-1'-yl]imidazo[1,2-a]pyridine-7-sulfonamide;(1S)-1'-[8-(2-amino-3-chloro-4-pyridinyl)-7-methylimidazo[1,2-a]pyridin-5-yl]spiro[1,3-dihydroindene-2,4'-piperidine]-1-amine (CID 165077491) is (1S)-1'-[7-amino-8-(2-amino-3-chloro-4-pyridinyl)imidazo[1,2-a]pyridin-5-yl]spiro[1,3-dihydroindene-2,4'-piperidine]-1-amine;(3R)-1'-[7-amino-8-(2-amino-3-chloro-4-pyridinyl)imidazo[1,2-a]pyridin-5-yl]spiro[3H-furo[2,3-b]pyridine-2,4'-piperidine]-3-amine;[8-(2-amino-3-chloro-4-pyridinyl)-5-[(5S)-5-aminospiro[5,7-dihydrocyclopenta[b]pyridine-6,4'-piperidine]-1'-yl]imidazo[1,2-a]pyridin-7-yl]methanol;8-(2-amino-3-chloro-4-pyridinyl)-5-[(1S)-1-aminospiro[1,3-dihydroindene-2,4'-piperidine]-1'-yl]imidazo[1,2-a]pyridine-7-sulfonamide;(1S)-1'-[8-(2-amino-3-chloro-4-pyridinyl)-7-methylimidazo[1,2-a]pyridin-5-yl]spiro[1,3-dihydroindene-2,4'-piperidine]-1-amine.

What is the SMILES notation for (1S)-1'-[7-amino-8-(2-amino-3-chloro-4-pyridinyl)imidazo[1,2-a]pyridin-5-yl]spiro[1,3-dihydroindene-2,4'-piperidine]-1-amine;(3R)-1'-[7-amino-8-(2-amino-3-chloro-4-pyridinyl)imidazo[1,2-a]pyridin-5-yl]spiro[3H-furo[2,3-b]pyridine-2,4'-piperidine]-3-amine;[8-(2-amino-3-chloro-4-pyridinyl)-5-[(5S)-5-aminospiro[5,7-dihydrocyclopenta[b]pyridine-6,4'-piperidine]-1'-yl]imidazo[1,2-a]pyridin-7-yl]methanol;8-(2-amino-3-chloro-4-pyridinyl)-5-[(1S)-1-aminospiro[1,3-dihydroindene-2,4'-piperidine]-1'-yl]imidazo[1,2-a]pyridine-7-sulfonamide;(1S)-1'-[8-(2-amino-3-chloro-4-pyridinyl)-7-methylimidazo[1,2-a]pyridin-5-yl]spiro[1,3-dihydroindene-2,4'-piperidine]-1-amine?

The canonical SMILES for (1S)-1'-[7-amino-8-(2-amino-3-chloro-4-pyridinyl)imidazo[1,2-a]pyridin-5-yl]spiro[1,3-dihydroindene-2,4'-piperidine]-1-amine;(3R)-1'-[7-amino-8-(2-amino-3-chloro-4-pyridinyl)imidazo[1,2-a]pyridin-5-yl]spiro[3H-furo[2,3-b]pyridine-2,4'-piperidine]-3-amine;[8-(2-amino-3-chloro-4-pyridinyl)-5-[(5S)-5-aminospiro[5,7-dihydrocyclopenta[b]pyridine-6,4'-piperidine]-1'-yl]imidazo[1,2-a]pyridin-7-yl]methanol;8-(2-amino-3-chloro-4-pyridinyl)-5-[(1S)-1-aminospiro[1,3-dihydroindene-2,4'-piperidine]-1'-yl]imidazo[1,2-a]pyridine-7-sulfonamide;(1S)-1'-[8-(2-amino-3-chloro-4-pyridinyl)-7-methylimidazo[1,2-a]pyridin-5-yl]spiro[1,3-dihydroindene-2,4'-piperidine]-1-amine is Cc1cc(N2CCC3(CC2)Cc2ccccc2[C@H]3N)n2ccnc2c1-c1ccnc(N)c1Cl.Nc1cc(N2CCC3(CC2)Cc2ccccc2[C@H]3N)n2ccnc2c1-c1ccnc(N)c1Cl.Nc1cc(N2CCC3(CC2)Oc2ncccc2[C@H]3N)n2ccnc2c1-c1ccnc(N)c1Cl.Nc1nccc(-c2c(CO)cc(N3CCC4(CC3)Cc3ncccc3[C@H]4N)n3ccnc23)c1Cl.Nc1nccc(-c2c(S(N)(=O)=O)cc(N3CCC4(CC3)Cc3ccccc3[C@H]4N)n3ccnc23)c1Cl.

What is the InChIKey of (1S)-1'-[7-amino-8-(2-amino-3-chloro-4-pyridinyl)imidazo[1,2-a]pyridin-5-yl]spiro[1,3-dihydroindene-2,4'-piperidine]-1-amine;(3R)-1'-[7-amino-8-(2-amino-3-chloro-4-pyridinyl)imidazo[1,2-a]pyridin-5-yl]spiro[3H-furo[2,3-b]pyridine-2,4'-piperidine]-3-amine;[8-(2-amino-3-chloro-4-pyridinyl)-5-[(5S)-5-aminospiro[5,7-dihydrocyclopenta[b]pyridine-6,4'-piperidine]-1'-yl]imidazo[1,2-a]pyridin-7-yl]methanol;8-(2-amino-3-chloro-4-pyridinyl)-5-[(1S)-1-aminospiro[1,3-dihydroindene-2,4'-piperidine]-1'-yl]imidazo[1,2-a]pyridine-7-sulfonamide;(1S)-1'-[8-(2-amino-3-chloro-4-pyridinyl)-7-methylimidazo[1,2-a]pyridin-5-yl]spiro[1,3-dihydroindene-2,4'-piperidine]-1-amine?

The InChIKey is UODJOEWMUNEDPY-HKZJWQGLSA-N. The full InChI is InChI=1S/C26H27ClN6.C25H26ClN7O2S.C25H26ClN7O.C25H26ClN7.C23H23ClN8O/c1-16-14-20(33-13-10-31-25(33)21(16)19-6-9-30-24(29)22(19)27)32-11-7-26(8-12-32)15-17-4-2-3-5-18(17)23(26)28;26-21-17(5-8-30-23(21)28)20-18(36(29,34)35)13-19(33-12-9-31-24(20)33)32-10-6-25(7-11-32)14-15-3-1-2-4-16(15)22(25)27;26-21-17(3-7-30-23(21)28)20-15(14-34)12-19(33-11-8-31-24(20)33)32-9-4-25(5-10-32)13-18-16(22(25)27)2-1-6-29-18;26-21-17(5-8-30-23(21)29)20-18(27)13-19(33-12-9-31-24(20)33)32-10-6-25(7-11-32)14-15-3-1-2-4-16(15)22(25)28;24-18-13(3-7-28-20(18)27)17-15(25)12-16(32-11-8-29-21(17)32)31-9-4-23(5-10-31)19(26)14-2-1-6-30-22(14)33-23/h2-6,9-10,13-14,23H,7-8,11-12,15,28H2,1H3,(H2,29,30);1-5,8-9,12-13,22H,6-7,10-11,14,27H2,(H2,28,30)(H2,29,34,35);1-3,6-8,11-12,22,34H,4-5,9-10,13-14,27H2,(H2,28,30);1-5,8-9,12-13,22H,6-7,10-11,14,27-28H2,(H2,29,30);1-3,6-8,11-12,19H,4-5,9-10,25-26H2,(H2,27,28)/t23-;3*22-;19-/m11111/s1.

What are the key properties of (1S)-1'-[7-amino-8-(2-amino-3-chloro-4-pyridinyl)imidazo[1,2-a]pyridin-5-yl]spiro[1,3-dihydroindene-2,4'-piperidine]-1-amine;(3R)-1'-[7-amino-8-(2-amino-3-chloro-4-pyridinyl)imidazo[1,2-a]pyridin-5-yl]spiro[3H-furo[2,3-b]pyridine-2,4'-piperidine]-3-amine;[8-(2-amino-3-chloro-4-pyridinyl)-5-[(5S)-5-aminospiro[5,7-dihydrocyclopenta[b]pyridine-6,4'-piperidine]-1'-yl]imidazo[1,2-a]pyridin-7-yl]methanol;8-(2-amino-3-chloro-4-pyridinyl)-5-[(1S)-1-aminospiro[1,3-dihydroindene-2,4'-piperidine]-1'-yl]imidazo[1,2-a]pyridine-7-sulfonamide;(1S)-1'-[8-(2-amino-3-chloro-4-pyridinyl)-7-methylimidazo[1,2-a]pyridin-5-yl]spiro[1,3-dihydroindene-2,4'-piperidine]-1-amine?

(1S)-1'-[7-amino-8-(2-amino-3-chloro-4-pyridinyl)imidazo[1,2-a]pyridin-5-yl]spiro[1,3-dihydroindene-2,4'-piperidine]-1-amine;(3R)-1'-[7-amino-8-(2-amino-3-chloro-4-pyridinyl)imidazo[1,2-a]pyridin-5-yl]spiro[3H-furo[2,3-b]pyridine-2,4'-piperidine]-3-amine;[8-(2-amino-3-chloro-4-pyridinyl)-5-[(5S)-5-aminospiro[5,7-dihydrocyclopenta[b]pyridine-6,4'-piperidine]-1'-yl]imidazo[1,2-a]pyridin-7-yl]methanol;8-(2-amino-3-chloro-4-pyridinyl)-5-[(1S)-1-aminospiro[1,3-dihydroindene-2,4'-piperidine]-1'-yl]imidazo[1,2-a]pyridine-7-sulfonamide;(1S)-1'-[8-(2-amino-3-chloro-4-pyridinyl)-7-methylimidazo[1,2-a]pyridin-5-yl]spiro[1,3-dihydroindene-2,4'-piperidine]-1-amine has a molecular weight of 2381.96 g/mol, XLogP of 18.36, 12 rotatable bonds, 14 hydrogen bond donors, and 38 hydrogen bond acceptors.

Where does this data come from?

All data for (1S)-1'-[7-amino-8-(2-amino-3-chloro-4-pyridinyl)imidazo[1,2-a]pyridin-5-yl]spiro[1,3-dihydroindene-2,4'-piperidine]-1-amine;(3R)-1'-[7-amino-8-(2-amino-3-chloro-4-pyridinyl)imidazo[1,2-a]pyridin-5-yl]spiro[3H-furo[2,3-b]pyridine-2,4'-piperidine]-3-amine;[8-(2-amino-3-chloro-4-pyridinyl)-5-[(5S)-5-aminospiro[5,7-dihydrocyclopenta[b]pyridine-6,4'-piperidine]-1'-yl]imidazo[1,2-a]pyridin-7-yl]methanol;8-(2-amino-3-chloro-4-pyridinyl)-5-[(1S)-1-aminospiro[1,3-dihydroindene-2,4'-piperidine]-1'-yl]imidazo[1,2-a]pyridine-7-sulfonamide;(1S)-1'-[8-(2-amino-3-chloro-4-pyridinyl)-7-methylimidazo[1,2-a]pyridin-5-yl]spiro[1,3-dihydroindene-2,4'-piperidine]-1-amine is sourced from PubChem (CID 165077491), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).