4-[6-[4-[3-(6-chloro-4-fluoro-2-pyridinyl)prop-2-ynoyl]piperazin-1-yl]-3-pyridinyl]-6-ethoxypyrazolo[1,5-a]pyridine-3-carbonitrile;6-ethoxy-4-[6-[4-[3-(2-fluoro-6-methoxy-4-pyridinyl)prop-2-ynoyl]piperazin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyridine-3-carbonitrile;6-ethoxy-4-[6-[4-[3-(4-fluoro-2-pyridinyl)prop-2-ynoyl]piperazin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyridine-3-carbonitrile;6-ethoxy-4-[6-[4-[3-(6-isocyano-2-pyridinyl)prop-2-ynoyl]piperazin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyridine-3-carbonitrile;6-ethoxy-4-[6-[4-[3-(5-nitro-3-pyridinyl)prop-2-ynoyl]piperazin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyridine-3-carbonitrile;6-ethoxy-4-[6-[4-[3-[5-(trifluoromethyl)-3-pyridinyl]prop-2-ynoyl]piperazin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyridine-3-carbonitrile

C165H133ClF6N44O15 — CID 165092419

About 4-[6-[4-[3-(6-chloro-4-fluoro-2-pyridinyl)prop-2-ynoyl]piperazin-1-yl]-3-pyridinyl]-6-ethoxypyrazolo[1,5-a]pyridine-3-carbonitrile;6-ethoxy-4-[6-[4-[3-(2-fluoro-6-methoxy-4-pyridinyl)prop-2-ynoyl]piperazin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyridine-3-carbonitrile;6-ethoxy-4-[6-[4-[3-(4-fluoro-2-pyridinyl)prop-2-ynoyl]piperazin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyridine-3-carbonitrile;6-ethoxy-4-[6-[4-[3-(6-isocyano-2-pyridinyl)prop-2-ynoyl]piperazin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyridine-3-carbonitrile;6-ethoxy-4-[6-[4-[3-(5-nitro-3-pyridinyl)prop-2-ynoyl]piperazin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyridine-3-carbonitrile;6-ethoxy-4-[6-[4-[3-[5-(trifluoromethyl)-3-pyridinyl]prop-2-ynoyl]piperazin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyridine-3-carbonitrile

4-[6-[4-[3-(6-chloro-4-fluoro-2-pyridinyl)prop-2-ynoyl]piperazin-1-yl]-3-pyridinyl]-6-ethoxypyrazolo[1,5-a]pyridine-3-carbonitrile;6-ethoxy-4-[6-[4-[3-(2-fluoro-6-methoxy-4-pyridinyl)prop-2-ynoyl]piperazin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyridine-3-carbonitrile;6-ethoxy-4-[6-[4-[3-(4-fluoro-2-pyridinyl)prop-2-ynoyl]piperazin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyridine-3-carbonitrile;6-ethoxy-4-[6-[4-[3-(6-isocyano-2-pyridinyl)prop-2-ynoyl]piperazin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyridine-3-carbonitrile;6-ethoxy-4-[6-[4-[3-(5-nitro-3-pyridinyl)prop-2-ynoyl]piperazin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyridine-3-carbonitrile;6-ethoxy-4-[6-[4-[3-[5-(trifluoromethyl)-3-pyridinyl]prop-2-ynoyl]piperazin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyridine-3-carbonitrile (PubChem CID 165092419) has the molecular formula C165H133ClF6N44O15 and a molecular weight of 3121.61 g/mol. Its IUPAC name is 4-[6-[4-[3-(6-chloro-4-fluoro-2-pyridinyl)prop-2-ynoyl]piperazin-1-yl]-3-pyridinyl]-6-ethoxypyrazolo[1,5-a]pyridine-3-carbonitrile;6-ethoxy-4-[6-[4-[3-(2-fluoro-6-methoxy-4-pyridinyl)prop-2-ynoyl]piperazin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyridine-3-carbonitrile;6-ethoxy-4-[6-[4-[3-(4-fluoro-2-pyridinyl)prop-2-ynoyl]piperazin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyridine-3-carbonitrile;6-ethoxy-4-[6-[4-[3-(6-isocyano-2-pyridinyl)prop-2-ynoyl]piperazin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyridine-3-carbonitrile;6-ethoxy-4-[6-[4-[3-(5-nitro-3-pyridinyl)prop-2-ynoyl]piperazin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyridine-3-carbonitrile;6-ethoxy-4-[6-[4-[3-[5-(trifluoromethyl)-3-pyridinyl]prop-2-ynoyl]piperazin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyridine-3-carbonitrile.

Molecular Properties

• Compound Name: 4-[6-[4-[3-(6-chloro-4-fluoro-2-pyridinyl)prop-2-ynoyl]piperazin-1-yl]-3-pyridinyl]-6-ethoxypyrazolo[1,5-a]pyridine-3-carbonitrile;6-ethoxy-4-[6-[4-[3-(2-fluoro-6-methoxy-4-pyridinyl)prop-2-ynoyl]piperazin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyridine-3-carbonitrile;6-ethoxy-4-[6-[4-[3-(4-fluoro-2-pyridinyl)prop-2-ynoyl]piperazin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyridine-3-carbonitrile;6-ethoxy-4-[6-[4-[3-(6-isocyano-2-pyridinyl)prop-2-ynoyl]piperazin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyridine-3-carbonitrile;6-ethoxy-4-[6-[4-[3-(5-nitro-3-pyridinyl)prop-2-ynoyl]piperazin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyridine-3-carbonitrile;6-ethoxy-4-[6-[4-[3-[5-(trifluoromethyl)-3-pyridinyl]prop-2-ynoyl]piperazin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyridine-3-carbonitrile
• PubChem CID: 165092419
• Molecular Formula: C165H133ClF6N44O15
• Molecular Weight: 3121.61 g/mol
• Exact Mass: 3119.06
• IUPAC Name: 4-[6-[4-[3-(6-chloro-4-fluoro-2-pyridinyl)prop-2-ynoyl]piperazin-1-yl]-3-pyridinyl]-6-ethoxypyrazolo[1,5-a]pyridine-3-carbonitrile;6-ethoxy-4-[6-[4-[3-(2-fluoro-6-methoxy-4-pyridinyl)prop-2-ynoyl]piperazin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyridine-3-carbonitrile;6-ethoxy-4-[6-[4-[3-(4-fluoro-2-pyridinyl)prop-2-ynoyl]piperazin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyridine-3-carbonitrile;6-ethoxy-4-[6-[4-[3-(6-isocyano-2-pyridinyl)prop-2-ynoyl]piperazin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyridine-3-carbonitrile;6-ethoxy-4-[6-[4-[3-(5-nitro-3-pyridinyl)prop-2-ynoyl]piperazin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyridine-3-carbonitrile;6-ethoxy-4-[6-[4-[3-[5-(trifluoromethyl)-3-pyridinyl]prop-2-ynoyl]piperazin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyridine-3-carbonitrile
• SMILES: CCOc1cc(-c2ccc(N3CCN(C(=O)C#Cc4cc(F)cc(Cl)n4)CC3)nc2)c2c(C#N)cnn2c1.CCOc1cc(-c2ccc(N3CCN(C(=O)C#Cc4cc(F)ccn4)CC3)nc2)c2c(C#N)cnn2c1.CCOc1cc(-c2ccc(N3CCN(C(=O)C#Cc4cc(F)nc(OC)c4)CC3)nc2)c2c(C#N)cnn2c1.CCOc1cc(-c2ccc(N3CCN(C(=O)C#Cc4cncc(C(F)(F)F)c4)CC3)nc2)c2c(C#N)cnn2c1.CCOc1cc(-c2ccc(N3CCN(C(=O)C#Cc4cncc([N+](=O)[O-])c4)CC3)nc2)c2c(C#N)cnn2c1.[C-]#[N+]c1cccc(C#CC(=O)N2CCN(c3ccc(-c4cc(OCC)cn5ncc(C#N)c45)cn3)CC2)n1
• InChI: InChI=1S/C28H22F3N7O2.C28H24FN7O3.C28H22N8O2.C27H21ClFN7O2.C27H22FN7O2.C27H22N8O4/c1-2-40-23-12-24(27-21(13-32)16-35-38(27)18-23)20-4-5-25(34-15-20)36-7-9-37(10-8-36)26(39)6-3-19-11-22(17-33-14-19)28(29,30)31;1-3-39-22-14-23(28-21(15-30)17-32-36(28)18-22)20-5-6-25(31-16-20)34-8-10-35(11-9-34)27(37)7-4-19-12-24(29)33-26(13-19)38-2;1-3-38-23-15-24(28-21(16-29)18-32-36(28)19-23)20-7-9-26(31-17-20)34-11-13-35(14-12-34)27(37)10-8-22-5-4-6-25(30-2)33-22;1-2-38-22-13-23(27-19(14-30)16-32-36(27)17-22)18-3-5-25(31-15-18)34-7-9-35(10-8-34)26(37)6-4-21-11-20(29)12-24(28)33-21;1-2-37-23-14-24(27-20(15-29)17-32-35(27)18-23)19-3-5-25(31-16-19)33-9-11-34(12-10-33)26(36)6-4-22-13-21(28)7-8-30-22;1-2-39-23-12-24(27-21(13-28)16-31-34(27)18-23)20-4-5-25(30-15-20)32-7-9-33(10-8-32)26(36)6-3-19-11-22(35(37)38)17-29-14-19/h4-5,11-12,14-18H,2,7-10H2,1H3;5-6,12-14,16-18H,3,8-11H2,1-2H3;4-7,9,15,17-19H,3,11-14H2,1H3;3,5,11-13,15-17H,2,7-10H2,1H3;3,5,7-8,13-14,16-18H,2,9-12H2,1H3;4-5,11-12,14-18H,2,7-10H2,1H3
• InChIKey: WYAWYENRHIYMAB-UHFFFAOYSA-N
• XLogP: 19.13
• TPSA: 654.63 Ų
• H-Bond Acceptors: 51
• Rotatable Bonds: 26
• Heavy Atoms: 231
• Complexity: —

Lipinski Rule of Five

3 violations

Rule	Value
MW ≤ 500	3121.61
LogP ≤ 5	19.13
H-Bond Donors ≤ 5	0
H-Bond Acceptors ≤ 10	51

Computed Properties (RDKit)

• Structural Alerts: {'alert_name': '2-halo_pyridine', 'substructure': 'N/A'}, {'alert_name': 'Carbo_cation/anion', 'substructure': 'N/A'}, {'alert_name': 'nitro_group', 'substructure': 'N/A'}, {'alert_name': 'Oxygen-nitrogen_single_bond', 'substructure': 'N/A'}, {'alert_name': 'triple_bond', 'substructure': 'N/A'}

Frequently Asked Questions

What is the IUPAC name of 4-[6-[4-[3-(6-chloro-4-fluoro-2-pyridinyl)prop-2-ynoyl]piperazin-1-yl]-3-pyridinyl]-6-ethoxypyrazolo[1,5-a]pyridine-3-carbonitrile;6-ethoxy-4-[6-[4-[3-(2-fluoro-6-methoxy-4-pyridinyl)prop-2-ynoyl]piperazin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyridine-3-carbonitrile;6-ethoxy-4-[6-[4-[3-(4-fluoro-2-pyridinyl)prop-2-ynoyl]piperazin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyridine-3-carbonitrile;6-ethoxy-4-[6-[4-[3-(6-isocyano-2-pyridinyl)prop-2-ynoyl]piperazin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyridine-3-carbonitrile;6-ethoxy-4-[6-[4-[3-(5-nitro-3-pyridinyl)prop-2-ynoyl]piperazin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyridine-3-carbonitrile;6-ethoxy-4-[6-[4-[3-[5-(trifluoromethyl)-3-pyridinyl]prop-2-ynoyl]piperazin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyridine-3-carbonitrile?

The IUPAC name of 4-[6-[4-[3-(6-chloro-4-fluoro-2-pyridinyl)prop-2-ynoyl]piperazin-1-yl]-3-pyridinyl]-6-ethoxypyrazolo[1,5-a]pyridine-3-carbonitrile;6-ethoxy-4-[6-[4-[3-(2-fluoro-6-methoxy-4-pyridinyl)prop-2-ynoyl]piperazin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyridine-3-carbonitrile;6-ethoxy-4-[6-[4-[3-(4-fluoro-2-pyridinyl)prop-2-ynoyl]piperazin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyridine-3-carbonitrile;6-ethoxy-4-[6-[4-[3-(6-isocyano-2-pyridinyl)prop-2-ynoyl]piperazin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyridine-3-carbonitrile;6-ethoxy-4-[6-[4-[3-(5-nitro-3-pyridinyl)prop-2-ynoyl]piperazin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyridine-3-carbonitrile;6-ethoxy-4-[6-[4-[3-[5-(trifluoromethyl)-3-pyridinyl]prop-2-ynoyl]piperazin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyridine-3-carbonitrile (CID 165092419) is 4-[6-[4-[3-(6-chloro-4-fluoro-2-pyridinyl)prop-2-ynoyl]piperazin-1-yl]-3-pyridinyl]-6-ethoxypyrazolo[1,5-a]pyridine-3-carbonitrile;6-ethoxy-4-[6-[4-[3-(2-fluoro-6-methoxy-4-pyridinyl)prop-2-ynoyl]piperazin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyridine-3-carbonitrile;6-ethoxy-4-[6-[4-[3-(4-fluoro-2-pyridinyl)prop-2-ynoyl]piperazin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyridine-3-carbonitrile;6-ethoxy-4-[6-[4-[3-(6-isocyano-2-pyridinyl)prop-2-ynoyl]piperazin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyridine-3-carbonitrile;6-ethoxy-4-[6-[4-[3-(5-nitro-3-pyridinyl)prop-2-ynoyl]piperazin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyridine-3-carbonitrile;6-ethoxy-4-[6-[4-[3-[5-(trifluoromethyl)-3-pyridinyl]prop-2-ynoyl]piperazin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyridine-3-carbonitrile.

What is the SMILES notation for 4-[6-[4-[3-(6-chloro-4-fluoro-2-pyridinyl)prop-2-ynoyl]piperazin-1-yl]-3-pyridinyl]-6-ethoxypyrazolo[1,5-a]pyridine-3-carbonitrile;6-ethoxy-4-[6-[4-[3-(2-fluoro-6-methoxy-4-pyridinyl)prop-2-ynoyl]piperazin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyridine-3-carbonitrile;6-ethoxy-4-[6-[4-[3-(4-fluoro-2-pyridinyl)prop-2-ynoyl]piperazin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyridine-3-carbonitrile;6-ethoxy-4-[6-[4-[3-(6-isocyano-2-pyridinyl)prop-2-ynoyl]piperazin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyridine-3-carbonitrile;6-ethoxy-4-[6-[4-[3-(5-nitro-3-pyridinyl)prop-2-ynoyl]piperazin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyridine-3-carbonitrile;6-ethoxy-4-[6-[4-[3-[5-(trifluoromethyl)-3-pyridinyl]prop-2-ynoyl]piperazin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyridine-3-carbonitrile?

The canonical SMILES for 4-[6-[4-[3-(6-chloro-4-fluoro-2-pyridinyl)prop-2-ynoyl]piperazin-1-yl]-3-pyridinyl]-6-ethoxypyrazolo[1,5-a]pyridine-3-carbonitrile;6-ethoxy-4-[6-[4-[3-(2-fluoro-6-methoxy-4-pyridinyl)prop-2-ynoyl]piperazin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyridine-3-carbonitrile;6-ethoxy-4-[6-[4-[3-(4-fluoro-2-pyridinyl)prop-2-ynoyl]piperazin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyridine-3-carbonitrile;6-ethoxy-4-[6-[4-[3-(6-isocyano-2-pyridinyl)prop-2-ynoyl]piperazin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyridine-3-carbonitrile;6-ethoxy-4-[6-[4-[3-(5-nitro-3-pyridinyl)prop-2-ynoyl]piperazin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyridine-3-carbonitrile;6-ethoxy-4-[6-[4-[3-[5-(trifluoromethyl)-3-pyridinyl]prop-2-ynoyl]piperazin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyridine-3-carbonitrile is CCOc1cc(-c2ccc(N3CCN(C(=O)C#Cc4cc(F)cc(Cl)n4)CC3)nc2)c2c(C#N)cnn2c1.CCOc1cc(-c2ccc(N3CCN(C(=O)C#Cc4cc(F)ccn4)CC3)nc2)c2c(C#N)cnn2c1.CCOc1cc(-c2ccc(N3CCN(C(=O)C#Cc4cc(F)nc(OC)c4)CC3)nc2)c2c(C#N)cnn2c1.CCOc1cc(-c2ccc(N3CCN(C(=O)C#Cc4cncc(C(F)(F)F)c4)CC3)nc2)c2c(C#N)cnn2c1.CCOc1cc(-c2ccc(N3CCN(C(=O)C#Cc4cncc([N+](=O)[O-])c4)CC3)nc2)c2c(C#N)cnn2c1.[C-]#[N+]c1cccc(C#CC(=O)N2CCN(c3ccc(-c4cc(OCC)cn5ncc(C#N)c45)cn3)CC2)n1.

What is the InChIKey of 4-[6-[4-[3-(6-chloro-4-fluoro-2-pyridinyl)prop-2-ynoyl]piperazin-1-yl]-3-pyridinyl]-6-ethoxypyrazolo[1,5-a]pyridine-3-carbonitrile;6-ethoxy-4-[6-[4-[3-(2-fluoro-6-methoxy-4-pyridinyl)prop-2-ynoyl]piperazin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyridine-3-carbonitrile;6-ethoxy-4-[6-[4-[3-(4-fluoro-2-pyridinyl)prop-2-ynoyl]piperazin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyridine-3-carbonitrile;6-ethoxy-4-[6-[4-[3-(6-isocyano-2-pyridinyl)prop-2-ynoyl]piperazin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyridine-3-carbonitrile;6-ethoxy-4-[6-[4-[3-(5-nitro-3-pyridinyl)prop-2-ynoyl]piperazin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyridine-3-carbonitrile;6-ethoxy-4-[6-[4-[3-[5-(trifluoromethyl)-3-pyridinyl]prop-2-ynoyl]piperazin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyridine-3-carbonitrile?

The InChIKey is WYAWYENRHIYMAB-UHFFFAOYSA-N. The full InChI is InChI=1S/C28H22F3N7O2.C28H24FN7O3.C28H22N8O2.C27H21ClFN7O2.C27H22FN7O2.C27H22N8O4/c1-2-40-23-12-24(27-21(13-32)16-35-38(27)18-23)20-4-5-25(34-15-20)36-7-9-37(10-8-36)26(39)6-3-19-11-22(17-33-14-19)28(29,30)31;1-3-39-22-14-23(28-21(15-30)17-32-36(28)18-22)20-5-6-25(31-16-20)34-8-10-35(11-9-34)27(37)7-4-19-12-24(29)33-26(13-19)38-2;1-3-38-23-15-24(28-21(16-29)18-32-36(28)19-23)20-7-9-26(31-17-20)34-11-13-35(14-12-34)27(37)10-8-22-5-4-6-25(30-2)33-22;1-2-38-22-13-23(27-19(14-30)16-32-36(27)17-22)18-3-5-25(31-15-18)34-7-9-35(10-8-34)26(37)6-4-21-11-20(29)12-24(28)33-21;1-2-37-23-14-24(27-20(15-29)17-32-35(27)18-23)19-3-5-25(31-16-19)33-9-11-34(12-10-33)26(36)6-4-22-13-21(28)7-8-30-22;1-2-39-23-12-24(27-21(13-28)16-31-34(27)18-23)20-4-5-25(30-15-20)32-7-9-33(10-8-32)26(36)6-3-19-11-22(35(37)38)17-29-14-19/h4-5,11-12,14-18H,2,7-10H2,1H3;5-6,12-14,16-18H,3,8-11H2,1-2H3;4-7,9,15,17-19H,3,11-14H2,1H3;3,5,11-13,15-17H,2,7-10H2,1H3;3,5,7-8,13-14,16-18H,2,9-12H2,1H3;4-5,11-12,14-18H,2,7-10H2,1H3.

What are the key properties of 4-[6-[4-[3-(6-chloro-4-fluoro-2-pyridinyl)prop-2-ynoyl]piperazin-1-yl]-3-pyridinyl]-6-ethoxypyrazolo[1,5-a]pyridine-3-carbonitrile;6-ethoxy-4-[6-[4-[3-(2-fluoro-6-methoxy-4-pyridinyl)prop-2-ynoyl]piperazin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyridine-3-carbonitrile;6-ethoxy-4-[6-[4-[3-(4-fluoro-2-pyridinyl)prop-2-ynoyl]piperazin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyridine-3-carbonitrile;6-ethoxy-4-[6-[4-[3-(6-isocyano-2-pyridinyl)prop-2-ynoyl]piperazin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyridine-3-carbonitrile;6-ethoxy-4-[6-[4-[3-(5-nitro-3-pyridinyl)prop-2-ynoyl]piperazin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyridine-3-carbonitrile;6-ethoxy-4-[6-[4-[3-[5-(trifluoromethyl)-3-pyridinyl]prop-2-ynoyl]piperazin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyridine-3-carbonitrile?

4-[6-[4-[3-(6-chloro-4-fluoro-2-pyridinyl)prop-2-ynoyl]piperazin-1-yl]-3-pyridinyl]-6-ethoxypyrazolo[1,5-a]pyridine-3-carbonitrile;6-ethoxy-4-[6-[4-[3-(2-fluoro-6-methoxy-4-pyridinyl)prop-2-ynoyl]piperazin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyridine-3-carbonitrile;6-ethoxy-4-[6-[4-[3-(4-fluoro-2-pyridinyl)prop-2-ynoyl]piperazin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyridine-3-carbonitrile;6-ethoxy-4-[6-[4-[3-(6-isocyano-2-pyridinyl)prop-2-ynoyl]piperazin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyridine-3-carbonitrile;6-ethoxy-4-[6-[4-[3-(5-nitro-3-pyridinyl)prop-2-ynoyl]piperazin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyridine-3-carbonitrile;6-ethoxy-4-[6-[4-[3-[5-(trifluoromethyl)-3-pyridinyl]prop-2-ynoyl]piperazin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyridine-3-carbonitrile has a molecular weight of 3121.61 g/mol, XLogP of 19.13, 26 rotatable bonds, 0 hydrogen bond donors, and 51 hydrogen bond acceptors.

Where does this data come from?

All data for 4-[6-[4-[3-(6-chloro-4-fluoro-2-pyridinyl)prop-2-ynoyl]piperazin-1-yl]-3-pyridinyl]-6-ethoxypyrazolo[1,5-a]pyridine-3-carbonitrile;6-ethoxy-4-[6-[4-[3-(2-fluoro-6-methoxy-4-pyridinyl)prop-2-ynoyl]piperazin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyridine-3-carbonitrile;6-ethoxy-4-[6-[4-[3-(4-fluoro-2-pyridinyl)prop-2-ynoyl]piperazin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyridine-3-carbonitrile;6-ethoxy-4-[6-[4-[3-(6-isocyano-2-pyridinyl)prop-2-ynoyl]piperazin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyridine-3-carbonitrile;6-ethoxy-4-[6-[4-[3-(5-nitro-3-pyridinyl)prop-2-ynoyl]piperazin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyridine-3-carbonitrile;6-ethoxy-4-[6-[4-[3-[5-(trifluoromethyl)-3-pyridinyl]prop-2-ynoyl]piperazin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyridine-3-carbonitrile is sourced from PubChem (CID 165092419), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).