About 6-[[ethyl(methyl)amino]sulfanylamino]-3-fluoro-2-[(5-fluoro-4-oxo-3H-quinazolin-6-yl)amino]benzonitrile;1-oxa-8-azaspiro[4.5]decane
6-[[ethyl(methyl)amino]sulfanylamino]-3-fluoro-2-[(5-fluoro-4-oxo-3H-quinazolin-6-yl)amino]benzonitrile;1-oxa-8-azaspiro[4.5]decane (PubChem CID 166169023) has the molecular formula C26H31F2N7O2S
and a molecular weight of 543.64 g/mol. Its IUPAC name is 6-[[ethyl(methyl)amino]sulfanylamino]-3-fluoro-2-[(5-fluoro-4-oxo-3H-quinazolin-6-yl)amino]benzonitrile;1-oxa-8-azaspiro[4.5]decane.
Molecular Properties
| Compound Name | 6-[[ethyl(methyl)amino]sulfanylamino]-3-fluoro-2-[(5-fluoro-4-oxo-3H-quinazolin-6-yl)amino]benzonitrile;1-oxa-8-azaspiro[4.5]decane |
| PubChem CID | 166169023 |
| Molecular Formula | C26H31F2N7O2S |
| Molecular Weight | 543.64 g/mol |
| Exact Mass | 543.22 |
| IUPAC Name | 6-[[ethyl(methyl)amino]sulfanylamino]-3-fluoro-2-[(5-fluoro-4-oxo-3H-quinazolin-6-yl)amino]benzonitrile;1-oxa-8-azaspiro[4.5]decane |
| SMILES | C1COC2(C1)CCNCC2.CCN(C)SNc1ccc(F)c(Nc2ccc3nc[nH]c(=O)c3c2F)c1C#N |
| InChI | InChI=1S/C18H16F2N6OS.C8H15NO/c1-3-26(2)28-25-12-5-4-11(19)17(10(12)8-21)24-14-7-6-13-15(16(14)20)18(27)23-9-22-13;1-2-8(10-7-1)3-5-9-6-4-8/h4-7,9,24-25H,3H2,1-2H3,(H,22,23,27);9H,1-7H2 |
| InChIKey | ZJHAAUQLLZPKQM-UHFFFAOYSA-N |
| XLogP | 4.66 |
| TPSA | 118.10 Ų |
| H-Bond Donors | 4 |
| H-Bond Acceptors | 9 |
| Rotatable Bonds | 6 |
| Heavy Atoms | 38 |
| Complexity | — |
Lipinski Rule of Five
1 violation
| Rule | Value |
| MW ≤ 500 | 543.64 |
| LogP ≤ 5 | 4.66 |
| H-Bond Donors ≤ 5 | 4 |
| H-Bond Acceptors ≤ 10 | 9 |
Computed Properties (RDKit)
| Structural Alerts | {'alert_name': 'sulphur_nitrogen_single_bond', 'substructure': 'N/A'} |
|---|
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Frequently Asked Questions
What is the IUPAC name of 6-[[ethyl(methyl)amino]sulfanylamino]-3-fluoro-2-[(5-fluoro-4-oxo-3H-quinazolin-6-yl)amino]benzonitrile;1-oxa-8-azaspiro[4.5]decane?
The IUPAC name of 6-[[ethyl(methyl)amino]sulfanylamino]-3-fluoro-2-[(5-fluoro-4-oxo-3H-quinazolin-6-yl)amino]benzonitrile;1-oxa-8-azaspiro[4.5]decane (CID 166169023) is 6-[[ethyl(methyl)amino]sulfanylamino]-3-fluoro-2-[(5-fluoro-4-oxo-3H-quinazolin-6-yl)amino]benzonitrile;1-oxa-8-azaspiro[4.5]decane.
What is the SMILES notation for 6-[[ethyl(methyl)amino]sulfanylamino]-3-fluoro-2-[(5-fluoro-4-oxo-3H-quinazolin-6-yl)amino]benzonitrile;1-oxa-8-azaspiro[4.5]decane?
The canonical SMILES for 6-[[ethyl(methyl)amino]sulfanylamino]-3-fluoro-2-[(5-fluoro-4-oxo-3H-quinazolin-6-yl)amino]benzonitrile;1-oxa-8-azaspiro[4.5]decane is C1COC2(C1)CCNCC2.CCN(C)SNc1ccc(F)c(Nc2ccc3nc[nH]c(=O)c3c2F)c1C#N.
What is the InChIKey of 6-[[ethyl(methyl)amino]sulfanylamino]-3-fluoro-2-[(5-fluoro-4-oxo-3H-quinazolin-6-yl)amino]benzonitrile;1-oxa-8-azaspiro[4.5]decane?
The InChIKey is ZJHAAUQLLZPKQM-UHFFFAOYSA-N. The full InChI is InChI=1S/C18H16F2N6OS.C8H15NO/c1-3-26(2)28-25-12-5-4-11(19)17(10(12)8-21)24-14-7-6-13-15(16(14)20)18(27)23-9-22-13;1-2-8(10-7-1)3-5-9-6-4-8/h4-7,9,24-25H,3H2,1-2H3,(H,22,23,27);9H,1-7H2.
What are the key properties of 6-[[ethyl(methyl)amino]sulfanylamino]-3-fluoro-2-[(5-fluoro-4-oxo-3H-quinazolin-6-yl)amino]benzonitrile;1-oxa-8-azaspiro[4.5]decane?
6-[[ethyl(methyl)amino]sulfanylamino]-3-fluoro-2-[(5-fluoro-4-oxo-3H-quinazolin-6-yl)amino]benzonitrile;1-oxa-8-azaspiro[4.5]decane has a molecular weight of 543.64 g/mol, XLogP of 4.66, 6 rotatable bonds, 4 hydrogen bond donors, and 9 hydrogen bond acceptors.
Where does this data come from?
All data for 6-[[ethyl(methyl)amino]sulfanylamino]-3-fluoro-2-[(5-fluoro-4-oxo-3H-quinazolin-6-yl)amino]benzonitrile;1-oxa-8-azaspiro[4.5]decane is sourced from PubChem (CID 166169023), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).