N-[6-(difluoromethyl)-2-pyridinyl]-2-piperidin-4-yl-7-propan-2-yloxyimidazo[1,2-a]pyridine-6-carboxamide

C22H25F2N5O2 — CID 166472198

IUPACN-[6-(difluoromethyl)-2-pyridinyl]-2-piperidin-4-yl-7-propan-2-yloxyimidazo[1,2-a]pyridine-6-carboxamide
SMILESCC(C)Oc1cc2nc(C3CCNCC3)cn2cc1C(=O)Nc1cccc(C(F)F)n1
InChIInChI=1S/C22H25F2N5O2/c1-13(2)31-18-10-20-27-17(14-6-8-25-9-7-14)12-29(20)11-15(18)22(30)28-19-5-3-4-16(26-19)21(23)24/h3-5,10-14,21,25H,6-9H2,1-2H3,(H,26,28,30)
InChIKeyWBSXNIDJWFDPTD-UHFFFAOYSA-N
MW429.47 g/mol
LogP4.17
Rot. Bonds6

About N-[6-(difluoromethyl)-2-pyridinyl]-2-piperidin-4-yl-7-propan-2-yloxyimidazo[1,2-a]pyridine-6-carboxamide

N-[6-(difluoromethyl)-2-pyridinyl]-2-piperidin-4-yl-7-propan-2-yloxyimidazo[1,2-a]pyridine-6-carboxamide (PubChem CID 166472198) has the molecular formula C22H25F2N5O2 and a molecular weight of 429.47 g/mol. Its IUPAC name is N-[6-(difluoromethyl)-2-pyridinyl]-2-piperidin-4-yl-7-propan-2-yloxyimidazo[1,2-a]pyridine-6-carboxamide.

Molecular Properties

Compound NameN-[6-(difluoromethyl)-2-pyridinyl]-2-piperidin-4-yl-7-propan-2-yloxyimidazo[1,2-a]pyridine-6-carboxamide
PubChem CID166472198
Molecular FormulaC22H25F2N5O2
Molecular Weight429.47 g/mol
Exact Mass429.20
IUPAC NameN-[6-(difluoromethyl)-2-pyridinyl]-2-piperidin-4-yl-7-propan-2-yloxyimidazo[1,2-a]pyridine-6-carboxamide
SMILESCC(C)Oc1cc2nc(C3CCNCC3)cn2cc1C(=O)Nc1cccc(C(F)F)n1
InChIInChI=1S/C22H25F2N5O2/c1-13(2)31-18-10-20-27-17(14-6-8-25-9-7-14)12-29(20)11-15(18)22(30)28-19-5-3-4-16(26-19)21(23)24/h3-5,10-14,21,25H,6-9H2,1-2H3,(H,26,28,30)
InChIKeyWBSXNIDJWFDPTD-UHFFFAOYSA-N
XLogP4.17
TPSA80.55 Ų
H-Bond Donors2
H-Bond Acceptors6
Rotatable Bonds6
Heavy Atoms31
Complexity—

Lipinski Rule of Five

Passes Rule of Five

RuleValue
MW ≤ 500429.47
LogP ≤ 54.17
H-Bond Donors ≤ 52
H-Bond Acceptors ≤ 106

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Related Compounds

2-cyclohexyl-7-propan-2-yloxy-N-[6-(trifluoromethyl)-2-pyridinyl]imidazo[1,2-a]pyridine-6-carboxamide;methanol
CID 166472332
N-[6-(difluoromethyl)-2-pyridinyl]-2-[1-[2-fluoro-2-[1-(4-nitrophenyl)piperidin-4-yl]ethyl]piperidin-4-yl]-7-propan-2-yloxyimidazo[1,2-a]pyridine-6-carboxamide
CID 175548958
N-[6-(cyanomethyl)-2-pyridinyl]-2-cyclopropyl-7-propan-2-yloxyimidazo[1,2-a]pyridine-6-carboxamide
CID 167420227
N-[6-(difluoromethyl)-2-pyridinyl]-2-[4-[[4-[4-(2,4-dioxo-1,3-diazinan-1-yl)phenyl]piperidin-1-yl]methyl]cyclohexyl]-7-propan-2-yloxyimidazo[1,2-a]pyridine-6-carboxamide
CID 167308835
N-[6-(difluoromethyl)-2-pyridinyl]-2-[1-[2-[4-[4-(2,6-dioxopiperidin-3-yl)-2,5-difluorophenyl]piperidin-1-yl]acetyl]piperidin-4-yl]-7-propan-2-yloxyimidazo[1,2-a]pyridine-6-carboxamide
CID 166472404
N-[6-(difluoromethyl)-2-pyridinyl]-2-[4-[[4-[1-(2,6-dioxopiperidin-3-yl)-3-methyl-2-oxobenzimidazol-5-yl]piperidin-1-yl]methyl]cyclohexyl]-7-propan-2-yloxyimidazo[1,2-a]pyridine-6-carboxamide
CID 166472214
N-[6-(difluoromethyl)-2-pyridinyl]-2-[(3S)-6-methyl-3-propa-1,2-dienyloxan-3-yl]-7-propan-2-yloxyimidazo[1,2-a]pyridine-6-carboxamide
CID 167143004
2-cyclohexyl-N-[6-(difluoromethyl)-2-pyridinyl]-7-propan-2-yloxyimidazo[1,2-a]pyridine-6-carboxamide;3-[4-[4-(dimethylamino)piperidin-1-yl]-3-methyl-2-oxobenzimidazol-1-yl]piperidine-2,6-dione
CID 166472374
N-(2-piperidin-4-yl-7-propan-2-yloxyimidazo[1,2-a]pyridin-6-yl)-6-(trifluoromethyl)pyridine-2-carboxamide
CID 166468246
N-[6-(difluoromethyl)-2-pyridinyl]-2-[4-[[5-[[4-(2,6-dioxopiperidin-3-yl)oxyphenyl]methyl]-2,5-diazaspiro[3.4]octan-2-yl]methyl]cyclohexyl]-7-propan-2-yloxyimidazo[1,2-a]pyridine-6-carboxamide
CID 166472055
7-cyclopentyloxy-2-cyclopropyl-N-(6-methoxy-2-pyridinyl)imidazo[1,2-a]pyridine-6-carboxamide
CID 167419980
3-chloro-N-[6-(difluoromethyl)-2-pyridinyl]-2-(1-methyl-2-oxabicyclo[2.1.1]hexan-4-yl)-7-propan-2-yloxyimidazo[1,2-a]pyridine-6-carboxamide
CID 155437318

Frequently Asked Questions

What is the IUPAC name of N-[6-(difluoromethyl)-2-pyridinyl]-2-piperidin-4-yl-7-propan-2-yloxyimidazo[1,2-a]pyridine-6-carboxamide?
The IUPAC name of N-[6-(difluoromethyl)-2-pyridinyl]-2-piperidin-4-yl-7-propan-2-yloxyimidazo[1,2-a]pyridine-6-carboxamide (CID 166472198) is N-[6-(difluoromethyl)-2-pyridinyl]-2-piperidin-4-yl-7-propan-2-yloxyimidazo[1,2-a]pyridine-6-carboxamide.
What is the SMILES notation for N-[6-(difluoromethyl)-2-pyridinyl]-2-piperidin-4-yl-7-propan-2-yloxyimidazo[1,2-a]pyridine-6-carboxamide?
The canonical SMILES for N-[6-(difluoromethyl)-2-pyridinyl]-2-piperidin-4-yl-7-propan-2-yloxyimidazo[1,2-a]pyridine-6-carboxamide is CC(C)Oc1cc2nc(C3CCNCC3)cn2cc1C(=O)Nc1cccc(C(F)F)n1.
What is the InChIKey of N-[6-(difluoromethyl)-2-pyridinyl]-2-piperidin-4-yl-7-propan-2-yloxyimidazo[1,2-a]pyridine-6-carboxamide?
The InChIKey is WBSXNIDJWFDPTD-UHFFFAOYSA-N. The full InChI is InChI=1S/C22H25F2N5O2/c1-13(2)31-18-10-20-27-17(14-6-8-25-9-7-14)12-29(20)11-15(18)22(30)28-19-5-3-4-16(26-19)21(23)24/h3-5,10-14,21,25H,6-9H2,1-2H3,(H,26,28,30).
What are the key properties of N-[6-(difluoromethyl)-2-pyridinyl]-2-piperidin-4-yl-7-propan-2-yloxyimidazo[1,2-a]pyridine-6-carboxamide?
N-[6-(difluoromethyl)-2-pyridinyl]-2-piperidin-4-yl-7-propan-2-yloxyimidazo[1,2-a]pyridine-6-carboxamide has a molecular weight of 429.47 g/mol, XLogP of 4.17, 6 rotatable bonds, 2 hydrogen bond donors, and 6 hydrogen bond acceptors.
Where does this data come from?
All data for N-[6-(difluoromethyl)-2-pyridinyl]-2-piperidin-4-yl-7-propan-2-yloxyimidazo[1,2-a]pyridine-6-carboxamide is sourced from PubChem (CID 166472198), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).