About 2-[2-[3-amino-5-(4-amino-2-oxa-8-azaspiro[4.5]decan-8-yl)pyrazin-2-yl]sulfanyl-6-(methylamino)phenyl]-2-fluoroacetaldehyde
2-[2-[3-amino-5-(4-amino-2-oxa-8-azaspiro[4.5]decan-8-yl)pyrazin-2-yl]sulfanyl-6-(methylamino)phenyl]-2-fluoroacetaldehyde (PubChem CID 166876538) has the molecular formula C21H27FN6O2S
and a molecular weight of 446.55 g/mol. Its IUPAC name is 2-[2-[3-amino-5-(4-amino-2-oxa-8-azaspiro[4.5]decan-8-yl)pyrazin-2-yl]sulfanyl-6-(methylamino)phenyl]-2-fluoroacetaldehyde.
Molecular Properties
| Compound Name | 2-[2-[3-amino-5-(4-amino-2-oxa-8-azaspiro[4.5]decan-8-yl)pyrazin-2-yl]sulfanyl-6-(methylamino)phenyl]-2-fluoroacetaldehyde |
| PubChem CID | 166876538 |
| Molecular Formula | C21H27FN6O2S |
| Molecular Weight | 446.55 g/mol |
| Exact Mass | 446.19 |
| IUPAC Name | 2-[2-[3-amino-5-(4-amino-2-oxa-8-azaspiro[4.5]decan-8-yl)pyrazin-2-yl]sulfanyl-6-(methylamino)phenyl]-2-fluoroacetaldehyde |
| SMILES | CNc1cccc(Sc2ncc(N3CCC4(CC3)COCC4N)nc2N)c1C(F)C=O |
| InChI | InChI=1S/C21H27FN6O2S/c1-25-14-3-2-4-15(18(14)13(22)10-29)31-20-19(24)27-17(9-26-20)28-7-5-21(6-8-28)12-30-11-16(21)23/h2-4,9-10,13,16,25H,5-8,11-12,23H2,1H3,(H2,24,27) |
| InChIKey | VDCGNUFUBBSBCF-UHFFFAOYSA-N |
| XLogP | 2.41 |
| TPSA | 119.39 Ų |
| H-Bond Donors | 3 |
| H-Bond Acceptors | 9 |
| Rotatable Bonds | 6 |
| Heavy Atoms | 31 |
| Complexity | — |
Lipinski Rule of Five
Passes Rule of Five
| Rule | Value |
| MW ≤ 500 | 446.55 |
| LogP ≤ 5 | 2.41 |
| H-Bond Donors ≤ 5 | 3 |
| H-Bond Acceptors ≤ 10 | 9 |
Computed Properties (RDKit)
| Structural Alerts | {'alert_name': 'aldehyde', 'substructure': 'N/A'} |
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Frequently Asked Questions
What is the IUPAC name of 2-[2-[3-amino-5-(4-amino-2-oxa-8-azaspiro[4.5]decan-8-yl)pyrazin-2-yl]sulfanyl-6-(methylamino)phenyl]-2-fluoroacetaldehyde?
The IUPAC name of 2-[2-[3-amino-5-(4-amino-2-oxa-8-azaspiro[4.5]decan-8-yl)pyrazin-2-yl]sulfanyl-6-(methylamino)phenyl]-2-fluoroacetaldehyde (CID 166876538) is 2-[2-[3-amino-5-(4-amino-2-oxa-8-azaspiro[4.5]decan-8-yl)pyrazin-2-yl]sulfanyl-6-(methylamino)phenyl]-2-fluoroacetaldehyde.
What is the SMILES notation for 2-[2-[3-amino-5-(4-amino-2-oxa-8-azaspiro[4.5]decan-8-yl)pyrazin-2-yl]sulfanyl-6-(methylamino)phenyl]-2-fluoroacetaldehyde?
The canonical SMILES for 2-[2-[3-amino-5-(4-amino-2-oxa-8-azaspiro[4.5]decan-8-yl)pyrazin-2-yl]sulfanyl-6-(methylamino)phenyl]-2-fluoroacetaldehyde is CNc1cccc(Sc2ncc(N3CCC4(CC3)COCC4N)nc2N)c1C(F)C=O.
What is the InChIKey of 2-[2-[3-amino-5-(4-amino-2-oxa-8-azaspiro[4.5]decan-8-yl)pyrazin-2-yl]sulfanyl-6-(methylamino)phenyl]-2-fluoroacetaldehyde?
The InChIKey is VDCGNUFUBBSBCF-UHFFFAOYSA-N. The full InChI is InChI=1S/C21H27FN6O2S/c1-25-14-3-2-4-15(18(14)13(22)10-29)31-20-19(24)27-17(9-26-20)28-7-5-21(6-8-28)12-30-11-16(21)23/h2-4,9-10,13,16,25H,5-8,11-12,23H2,1H3,(H2,24,27).
What are the key properties of 2-[2-[3-amino-5-(4-amino-2-oxa-8-azaspiro[4.5]decan-8-yl)pyrazin-2-yl]sulfanyl-6-(methylamino)phenyl]-2-fluoroacetaldehyde?
2-[2-[3-amino-5-(4-amino-2-oxa-8-azaspiro[4.5]decan-8-yl)pyrazin-2-yl]sulfanyl-6-(methylamino)phenyl]-2-fluoroacetaldehyde has a molecular weight of 446.55 g/mol, XLogP of 2.41, 6 rotatable bonds, 3 hydrogen bond donors, and 9 hydrogen bond acceptors.
Where does this data come from?
All data for 2-[2-[3-amino-5-(4-amino-2-oxa-8-azaspiro[4.5]decan-8-yl)pyrazin-2-yl]sulfanyl-6-(methylamino)phenyl]-2-fluoroacetaldehyde is sourced from PubChem (CID 166876538), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).