About 5-chloro-N-[3-fluoro-4-[2-(3-methyl-2H-pyrazolo[3,4-b]pyridin-5-yl)ethynyl]-2-pyridinyl]-2-methoxypyridine-3-sulfonamide
5-chloro-N-[3-fluoro-4-[2-(3-methyl-2H-pyrazolo[3,4-b]pyridin-5-yl)ethynyl]-2-pyridinyl]-2-methoxypyridine-3-sulfonamide (PubChem CID 166889265) has the molecular formula C20H14ClFN6O3S
and a molecular weight of 472.89 g/mol. Its IUPAC name is 5-chloro-N-[3-fluoro-4-[2-(3-methyl-2H-pyrazolo[3,4-b]pyridin-5-yl)ethynyl]-2-pyridinyl]-2-methoxypyridine-3-sulfonamide.
Molecular Properties
| Compound Name | 5-chloro-N-[3-fluoro-4-[2-(3-methyl-2H-pyrazolo[3,4-b]pyridin-5-yl)ethynyl]-2-pyridinyl]-2-methoxypyridine-3-sulfonamide |
| PubChem CID | 166889265 |
| Molecular Formula | C20H14ClFN6O3S |
| Molecular Weight | 472.89 g/mol |
| Exact Mass | 472.05 |
| IUPAC Name | 5-chloro-N-[3-fluoro-4-[2-(3-methyl-2H-pyrazolo[3,4-b]pyridin-5-yl)ethynyl]-2-pyridinyl]-2-methoxypyridine-3-sulfonamide |
| SMILES | COc1ncc(Cl)cc1S(=O)(=O)Nc1nccc(C#Cc2cnc3n[nH]c(C)c3c2)c1F |
| InChI | InChI=1S/C20H14ClFN6O3S/c1-11-15-7-12(9-24-18(15)27-26-11)3-4-13-5-6-23-19(17(13)22)28-32(29,30)16-8-14(21)10-25-20(16)31-2/h5-10H,1-2H3,(H,23,28)(H,24,26,27) |
| InChIKey | YUSGFBHQZDLMKX-UHFFFAOYSA-N |
| XLogP | 3.06 |
| TPSA | 122.75 Ų |
| H-Bond Donors | 2 |
| H-Bond Acceptors | 7 |
| Rotatable Bonds | 4 |
| Heavy Atoms | 32 |
| Complexity | — |
Lipinski Rule of Five
Passes Rule of Five
| Rule | Value |
| MW ≤ 500 | 472.89 |
| LogP ≤ 5 | 3.06 |
| H-Bond Donors ≤ 5 | 2 |
| H-Bond Acceptors ≤ 10 | 7 |
Computed Properties (RDKit)
| Structural Alerts | {'alert_name': 'triple_bond', 'substructure': 'N/A'} |
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Frequently Asked Questions
What is the IUPAC name of 5-chloro-N-[3-fluoro-4-[2-(3-methyl-2H-pyrazolo[3,4-b]pyridin-5-yl)ethynyl]-2-pyridinyl]-2-methoxypyridine-3-sulfonamide?
The IUPAC name of 5-chloro-N-[3-fluoro-4-[2-(3-methyl-2H-pyrazolo[3,4-b]pyridin-5-yl)ethynyl]-2-pyridinyl]-2-methoxypyridine-3-sulfonamide (CID 166889265) is 5-chloro-N-[3-fluoro-4-[2-(3-methyl-2H-pyrazolo[3,4-b]pyridin-5-yl)ethynyl]-2-pyridinyl]-2-methoxypyridine-3-sulfonamide.
What is the SMILES notation for 5-chloro-N-[3-fluoro-4-[2-(3-methyl-2H-pyrazolo[3,4-b]pyridin-5-yl)ethynyl]-2-pyridinyl]-2-methoxypyridine-3-sulfonamide?
The canonical SMILES for 5-chloro-N-[3-fluoro-4-[2-(3-methyl-2H-pyrazolo[3,4-b]pyridin-5-yl)ethynyl]-2-pyridinyl]-2-methoxypyridine-3-sulfonamide is COc1ncc(Cl)cc1S(=O)(=O)Nc1nccc(C#Cc2cnc3n[nH]c(C)c3c2)c1F.
What is the InChIKey of 5-chloro-N-[3-fluoro-4-[2-(3-methyl-2H-pyrazolo[3,4-b]pyridin-5-yl)ethynyl]-2-pyridinyl]-2-methoxypyridine-3-sulfonamide?
The InChIKey is YUSGFBHQZDLMKX-UHFFFAOYSA-N. The full InChI is InChI=1S/C20H14ClFN6O3S/c1-11-15-7-12(9-24-18(15)27-26-11)3-4-13-5-6-23-19(17(13)22)28-32(29,30)16-8-14(21)10-25-20(16)31-2/h5-10H,1-2H3,(H,23,28)(H,24,26,27).
What are the key properties of 5-chloro-N-[3-fluoro-4-[2-(3-methyl-2H-pyrazolo[3,4-b]pyridin-5-yl)ethynyl]-2-pyridinyl]-2-methoxypyridine-3-sulfonamide?
5-chloro-N-[3-fluoro-4-[2-(3-methyl-2H-pyrazolo[3,4-b]pyridin-5-yl)ethynyl]-2-pyridinyl]-2-methoxypyridine-3-sulfonamide has a molecular weight of 472.89 g/mol, XLogP of 3.06, 4 rotatable bonds, 2 hydrogen bond donors, and 7 hydrogen bond acceptors.
Where does this data come from?
All data for 5-chloro-N-[3-fluoro-4-[2-(3-methyl-2H-pyrazolo[3,4-b]pyridin-5-yl)ethynyl]-2-pyridinyl]-2-methoxypyridine-3-sulfonamide is sourced from PubChem (CID 166889265), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).