About N-[4-[2-(5-aminopyrido[3,4-b]pyrazin-8-yl)ethynyl]-3-fluoro-2-pyridinyl]-5-chloro-2-methoxypyridine-3-sulfonamide
N-[4-[2-(5-aminopyrido[3,4-b]pyrazin-8-yl)ethynyl]-3-fluoro-2-pyridinyl]-5-chloro-2-methoxypyridine-3-sulfonamide (PubChem CID 166889392) has the molecular formula C20H13ClFN7O3S
and a molecular weight of 485.89 g/mol. Its IUPAC name is N-[4-[2-(5-aminopyrido[3,4-b]pyrazin-8-yl)ethynyl]-3-fluoro-2-pyridinyl]-5-chloro-2-methoxypyridine-3-sulfonamide.
Molecular Properties
| Compound Name | N-[4-[2-(5-aminopyrido[3,4-b]pyrazin-8-yl)ethynyl]-3-fluoro-2-pyridinyl]-5-chloro-2-methoxypyridine-3-sulfonamide |
| PubChem CID | 166889392 |
| Molecular Formula | C20H13ClFN7O3S |
| Molecular Weight | 485.89 g/mol |
| Exact Mass | 485.05 |
| IUPAC Name | N-[4-[2-(5-aminopyrido[3,4-b]pyrazin-8-yl)ethynyl]-3-fluoro-2-pyridinyl]-5-chloro-2-methoxypyridine-3-sulfonamide |
| SMILES | COc1ncc(Cl)cc1S(=O)(=O)Nc1nccc(C#Cc2cnc(N)c3nccnc23)c1F |
| InChI | InChI=1S/C20H13ClFN7O3S/c1-32-20-14(8-13(21)10-28-20)33(30,31)29-19-15(22)11(4-5-26-19)2-3-12-9-27-18(23)17-16(12)24-6-7-25-17/h4-10H,1H3,(H2,23,27)(H,26,29) |
| InChIKey | RMZZLLFDDDQKAM-UHFFFAOYSA-N |
| XLogP | 2.40 |
| TPSA | 145.87 Ų |
| H-Bond Donors | 2 |
| H-Bond Acceptors | 9 |
| Rotatable Bonds | 4 |
| Heavy Atoms | 33 |
| Complexity | — |
Lipinski Rule of Five
Passes Rule of Five
| Rule | Value |
| MW ≤ 500 | 485.89 |
| LogP ≤ 5 | 2.40 |
| H-Bond Donors ≤ 5 | 2 |
| H-Bond Acceptors ≤ 10 | 9 |
Computed Properties (RDKit)
| Structural Alerts | {'alert_name': 'triple_bond', 'substructure': 'N/A'} |
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Frequently Asked Questions
What is the IUPAC name of N-[4-[2-(5-aminopyrido[3,4-b]pyrazin-8-yl)ethynyl]-3-fluoro-2-pyridinyl]-5-chloro-2-methoxypyridine-3-sulfonamide?
The IUPAC name of N-[4-[2-(5-aminopyrido[3,4-b]pyrazin-8-yl)ethynyl]-3-fluoro-2-pyridinyl]-5-chloro-2-methoxypyridine-3-sulfonamide (CID 166889392) is N-[4-[2-(5-aminopyrido[3,4-b]pyrazin-8-yl)ethynyl]-3-fluoro-2-pyridinyl]-5-chloro-2-methoxypyridine-3-sulfonamide.
What is the SMILES notation for N-[4-[2-(5-aminopyrido[3,4-b]pyrazin-8-yl)ethynyl]-3-fluoro-2-pyridinyl]-5-chloro-2-methoxypyridine-3-sulfonamide?
The canonical SMILES for N-[4-[2-(5-aminopyrido[3,4-b]pyrazin-8-yl)ethynyl]-3-fluoro-2-pyridinyl]-5-chloro-2-methoxypyridine-3-sulfonamide is COc1ncc(Cl)cc1S(=O)(=O)Nc1nccc(C#Cc2cnc(N)c3nccnc23)c1F.
What is the InChIKey of N-[4-[2-(5-aminopyrido[3,4-b]pyrazin-8-yl)ethynyl]-3-fluoro-2-pyridinyl]-5-chloro-2-methoxypyridine-3-sulfonamide?
The InChIKey is RMZZLLFDDDQKAM-UHFFFAOYSA-N. The full InChI is InChI=1S/C20H13ClFN7O3S/c1-32-20-14(8-13(21)10-28-20)33(30,31)29-19-15(22)11(4-5-26-19)2-3-12-9-27-18(23)17-16(12)24-6-7-25-17/h4-10H,1H3,(H2,23,27)(H,26,29).
What are the key properties of N-[4-[2-(5-aminopyrido[3,4-b]pyrazin-8-yl)ethynyl]-3-fluoro-2-pyridinyl]-5-chloro-2-methoxypyridine-3-sulfonamide?
N-[4-[2-(5-aminopyrido[3,4-b]pyrazin-8-yl)ethynyl]-3-fluoro-2-pyridinyl]-5-chloro-2-methoxypyridine-3-sulfonamide has a molecular weight of 485.89 g/mol, XLogP of 2.40, 4 rotatable bonds, 2 hydrogen bond donors, and 9 hydrogen bond acceptors.
Where does this data come from?
All data for N-[4-[2-(5-aminopyrido[3,4-b]pyrazin-8-yl)ethynyl]-3-fluoro-2-pyridinyl]-5-chloro-2-methoxypyridine-3-sulfonamide is sourced from PubChem (CID 166889392), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).