About N-(2-chloroquinolin-3-yl)-3-[(3S,4R)-1-(2-methoxyethyl)-4-phenylpyrrolidin-3-yl]propanamide
N-(2-chloroquinolin-3-yl)-3-[(3S,4R)-1-(2-methoxyethyl)-4-phenylpyrrolidin-3-yl]propanamide (PubChem CID 167179866) has the molecular formula C25H28ClN3O2
and a molecular weight of 437.97 g/mol. Its IUPAC name is N-(2-chloroquinolin-3-yl)-3-[(3S,4R)-1-(2-methoxyethyl)-4-phenylpyrrolidin-3-yl]propanamide.
Molecular Properties
| Compound Name | N-(2-chloroquinolin-3-yl)-3-[(3S,4R)-1-(2-methoxyethyl)-4-phenylpyrrolidin-3-yl]propanamide |
| PubChem CID | 167179866 |
| Molecular Formula | C25H28ClN3O2 |
| Molecular Weight | 437.97 g/mol |
| Exact Mass | 437.19 |
| IUPAC Name | N-(2-chloroquinolin-3-yl)-3-[(3S,4R)-1-(2-methoxyethyl)-4-phenylpyrrolidin-3-yl]propanamide |
| SMILES | COCCN1C[C@@H](CCC(=O)Nc2cc3ccccc3nc2Cl)[C@H](c2ccccc2)C1 |
| InChI | InChI=1S/C25H28ClN3O2/c1-31-14-13-29-16-20(21(17-29)18-7-3-2-4-8-18)11-12-24(30)27-23-15-19-9-5-6-10-22(19)28-25(23)26/h2-10,15,20-21H,11-14,16-17H2,1H3,(H,27,30)/t20-,21+/m1/s1 |
| InChIKey | VXVTVEGPIPMNMQ-RTWAWAEBSA-N |
| XLogP | 4.97 |
| TPSA | 54.46 Ų |
| H-Bond Donors | 1 |
| H-Bond Acceptors | 4 |
| Rotatable Bonds | 8 |
| Heavy Atoms | 31 |
| Complexity | — |
Lipinski Rule of Five
Passes Rule of Five
| Rule | Value |
| MW ≤ 500 | 437.97 |
| LogP ≤ 5 | 4.97 |
| H-Bond Donors ≤ 5 | 1 |
| H-Bond Acceptors ≤ 10 | 4 |
Computed Properties (RDKit)
| Structural Alerts | {'alert_name': '2-halo_pyridine', 'substructure': 'N/A'} |
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Frequently Asked Questions
What is the IUPAC name of N-(2-chloroquinolin-3-yl)-3-[(3S,4R)-1-(2-methoxyethyl)-4-phenylpyrrolidin-3-yl]propanamide?
The IUPAC name of N-(2-chloroquinolin-3-yl)-3-[(3S,4R)-1-(2-methoxyethyl)-4-phenylpyrrolidin-3-yl]propanamide (CID 167179866) is N-(2-chloroquinolin-3-yl)-3-[(3S,4R)-1-(2-methoxyethyl)-4-phenylpyrrolidin-3-yl]propanamide.
What is the SMILES notation for N-(2-chloroquinolin-3-yl)-3-[(3S,4R)-1-(2-methoxyethyl)-4-phenylpyrrolidin-3-yl]propanamide?
The canonical SMILES for N-(2-chloroquinolin-3-yl)-3-[(3S,4R)-1-(2-methoxyethyl)-4-phenylpyrrolidin-3-yl]propanamide is COCCN1C[C@@H](CCC(=O)Nc2cc3ccccc3nc2Cl)[C@H](c2ccccc2)C1.
What is the InChIKey of N-(2-chloroquinolin-3-yl)-3-[(3S,4R)-1-(2-methoxyethyl)-4-phenylpyrrolidin-3-yl]propanamide?
The InChIKey is VXVTVEGPIPMNMQ-RTWAWAEBSA-N. The full InChI is InChI=1S/C25H28ClN3O2/c1-31-14-13-29-16-20(21(17-29)18-7-3-2-4-8-18)11-12-24(30)27-23-15-19-9-5-6-10-22(19)28-25(23)26/h2-10,15,20-21H,11-14,16-17H2,1H3,(H,27,30)/t20-,21+/m1/s1.
What are the key properties of N-(2-chloroquinolin-3-yl)-3-[(3S,4R)-1-(2-methoxyethyl)-4-phenylpyrrolidin-3-yl]propanamide?
N-(2-chloroquinolin-3-yl)-3-[(3S,4R)-1-(2-methoxyethyl)-4-phenylpyrrolidin-3-yl]propanamide has a molecular weight of 437.97 g/mol, XLogP of 4.97, 8 rotatable bonds, 1 hydrogen bond donors, and 4 hydrogen bond acceptors.
Where does this data come from?
All data for N-(2-chloroquinolin-3-yl)-3-[(3S,4R)-1-(2-methoxyethyl)-4-phenylpyrrolidin-3-yl]propanamide is sourced from PubChem (CID 167179866), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).