2-fluoro-N-[2-hydroxy-1-methyl-3-(4-methyl-3-pyridinyl)-2H-1,6-naphthyridin-7-yl]cyclopropane-1-carboxamide

C19H19FN4O2 — CID 167188940

IUPAC2-fluoro-N-[2-hydroxy-1-methyl-3-(4-methyl-3-pyridinyl)-2H-1,6-naphthyridin-7-yl]cyclopropane-1-carboxamide
SMILESCc1ccncc1C1=Cc2cnc(NC(=O)C3CC3F)cc2N(C)C1O
InChIInChI=1S/C19H19FN4O2/c1-10-3-4-21-9-14(10)12-5-11-8-22-17(7-16(11)24(2)19(12)26)23-18(25)13-6-15(13)20/h3-5,7-9,13,15,19,26H,6H2,1-2H3,(H,22,23,25)
InChIKeyHAGVVJXUWPXYOK-UHFFFAOYSA-N
MW354.39 g/mol
LogP2.39
Rot. Bonds3

About 2-fluoro-N-[2-hydroxy-1-methyl-3-(4-methyl-3-pyridinyl)-2H-1,6-naphthyridin-7-yl]cyclopropane-1-carboxamide

2-fluoro-N-[2-hydroxy-1-methyl-3-(4-methyl-3-pyridinyl)-2H-1,6-naphthyridin-7-yl]cyclopropane-1-carboxamide (PubChem CID 167188940) has the molecular formula C19H19FN4O2 and a molecular weight of 354.39 g/mol. Its IUPAC name is 2-fluoro-N-[2-hydroxy-1-methyl-3-(4-methyl-3-pyridinyl)-2H-1,6-naphthyridin-7-yl]cyclopropane-1-carboxamide.

Molecular Properties

Compound Name2-fluoro-N-[2-hydroxy-1-methyl-3-(4-methyl-3-pyridinyl)-2H-1,6-naphthyridin-7-yl]cyclopropane-1-carboxamide
PubChem CID167188940
Molecular FormulaC19H19FN4O2
Molecular Weight354.39 g/mol
Exact Mass354.15
IUPAC Name2-fluoro-N-[2-hydroxy-1-methyl-3-(4-methyl-3-pyridinyl)-2H-1,6-naphthyridin-7-yl]cyclopropane-1-carboxamide
SMILESCc1ccncc1C1=Cc2cnc(NC(=O)C3CC3F)cc2N(C)C1O
InChIInChI=1S/C19H19FN4O2/c1-10-3-4-21-9-14(10)12-5-11-8-22-17(7-16(11)24(2)19(12)26)23-18(25)13-6-15(13)20/h3-5,7-9,13,15,19,26H,6H2,1-2H3,(H,22,23,25)
InChIKeyHAGVVJXUWPXYOK-UHFFFAOYSA-N
XLogP2.39
TPSA78.35 Ų
H-Bond Donors2
H-Bond Acceptors5
Rotatable Bonds3
Heavy Atoms26
Complexity—

Lipinski Rule of Five

Passes Rule of Five

RuleValue
MW ≤ 500354.39
LogP ≤ 52.39
H-Bond Donors ≤ 52
H-Bond Acceptors ≤ 105

Computed Properties (RDKit)

Structural Alerts{'alert_name': 'dyes5A(27)', 'substructure': 'N/A'}

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Related Compounds

cis-(1R,2R)-N-[1-ethyl-3-(5-fluoro-4-methyl-3-pyridinyl)-2-hydroxy-2H-1,6-naphthyridin-7-yl]-2-fluorocyclopropane-1-carboxamide
CID 167189108
cis-(1R,2R)-2-fluoro-N-[7-(4-methyl-3-pyridinyl)isoquinolin-3-yl]cyclopropane-1-carboxamide
CID 71115022
N-[1-ethyl-3-(4-methyl-3-pyridinyl)-2-oxo-1,6-naphthyridin-7-yl]-2-fluorocyclopropane-1-carboxamide
CID 166123847
N-[3-[6-(2,2-difluoro-1-hydroxypropyl)-4-methyl-3-pyridinyl]-2-hydroxy-1-methyl-2H-1,6-naphthyridin-7-yl]cyclopropanecarboxamide
CID 167188939
N-[2-hydroxy-3-[4-(1-hydroxypropyl)-2,6-dimethylphenyl]-1-methyl-2H-1,6-naphthyridin-7-yl]cyclopropanecarboxamide
CID 167189090
2-methyl-N-[7-(4-methyl-3-pyridinyl)isoquinolin-3-yl]cyclopropane-1-carboxamide
CID 123303699
cis-(1S,2S)-N-[8-chloro-6-(3-methyl-4-pyridinyl)isoquinolin-3-yl]-2-fluorocyclopropane-1-carboxamide
CID 140921567
N-[2-(4-cyclopropyloxy-3-pyridinyl)-1-methylpyrrolo[2,3-c]pyridin-5-yl]-2-fluorocyclopropane-1-carboxamide
CID 163252255
cis-(1S,2S)-2-fluoro-N-[6-(4-methyl-3-pyridinyl)-[1,3]thiazolo[4,5-b]pyridin-2-yl]cyclopropane-1-carboxamide
CID 138504770
cis-(1S,2S)-N-[1-(cyclopropylmethyl)-3-[4-[[2-[[7-[(2-fluorocyclopropanecarbonyl)amino]-3-(4-methyl-3-pyridinyl)-2-oxo-1,6-naphthyridin-1-yl]methyl]cyclopropyl]methyl]-3-pyridinyl]-2-oxo-1,6-naphthyridin-7-yl]-2-fluorocyclopropane-1-carboxamide
CID 167188740
N-[8-chloro-6-(4-methyl-3-pyridinyl)isoquinolin-3-yl]-2-methylcyclopropane-1-carboxamide
CID 175946191
2-fluoro-N-[3-(5-fluoro-2-methylphenyl)-1-methyl-2-oxo-1,6-naphthyridin-7-yl]cyclopropane-1-carboxamide
CID 166123806

Frequently Asked Questions

What is the IUPAC name of 2-fluoro-N-[2-hydroxy-1-methyl-3-(4-methyl-3-pyridinyl)-2H-1,6-naphthyridin-7-yl]cyclopropane-1-carboxamide?
The IUPAC name of 2-fluoro-N-[2-hydroxy-1-methyl-3-(4-methyl-3-pyridinyl)-2H-1,6-naphthyridin-7-yl]cyclopropane-1-carboxamide (CID 167188940) is 2-fluoro-N-[2-hydroxy-1-methyl-3-(4-methyl-3-pyridinyl)-2H-1,6-naphthyridin-7-yl]cyclopropane-1-carboxamide.
What is the SMILES notation for 2-fluoro-N-[2-hydroxy-1-methyl-3-(4-methyl-3-pyridinyl)-2H-1,6-naphthyridin-7-yl]cyclopropane-1-carboxamide?
The canonical SMILES for 2-fluoro-N-[2-hydroxy-1-methyl-3-(4-methyl-3-pyridinyl)-2H-1,6-naphthyridin-7-yl]cyclopropane-1-carboxamide is Cc1ccncc1C1=Cc2cnc(NC(=O)C3CC3F)cc2N(C)C1O.
What is the InChIKey of 2-fluoro-N-[2-hydroxy-1-methyl-3-(4-methyl-3-pyridinyl)-2H-1,6-naphthyridin-7-yl]cyclopropane-1-carboxamide?
The InChIKey is HAGVVJXUWPXYOK-UHFFFAOYSA-N. The full InChI is InChI=1S/C19H19FN4O2/c1-10-3-4-21-9-14(10)12-5-11-8-22-17(7-16(11)24(2)19(12)26)23-18(25)13-6-15(13)20/h3-5,7-9,13,15,19,26H,6H2,1-2H3,(H,22,23,25).
What are the key properties of 2-fluoro-N-[2-hydroxy-1-methyl-3-(4-methyl-3-pyridinyl)-2H-1,6-naphthyridin-7-yl]cyclopropane-1-carboxamide?
2-fluoro-N-[2-hydroxy-1-methyl-3-(4-methyl-3-pyridinyl)-2H-1,6-naphthyridin-7-yl]cyclopropane-1-carboxamide has a molecular weight of 354.39 g/mol, XLogP of 2.39, 3 rotatable bonds, 2 hydrogen bond donors, and 5 hydrogen bond acceptors.
Where does this data come from?
All data for 2-fluoro-N-[2-hydroxy-1-methyl-3-(4-methyl-3-pyridinyl)-2H-1,6-naphthyridin-7-yl]cyclopropane-1-carboxamide is sourced from PubChem (CID 167188940), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).