N-[6-[8-amino-1-[4-[(4-chloro-2-pyridinyl)carbamoyl]-2-fluorophenyl]-3-[2-[1-[2-(2,6-dioxopiperidin-3-yl)-6-fluoro-1,3-dioxoisoindol-5-yl]azetidin-3-yl]-2,7-diazaspiro[3.5]nonan-7-yl]imidazo[1,5-a]pyrazin-6-yl]-4-chloro-2-pyridinyl]-4-[8-amino-3-[2-[[1-[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-5-yl]azetidin-3-yl]methyl]-2,7-diazaspiro[3.5]nonan-7-yl]imidazo[1,5-a]pyrazin-1-yl]-3-fluorobenzamide

C83H73Cl2F3N22O10 — CID 167206743

About N-[6-[8-amino-1-[4-[(4-chloro-2-pyridinyl)carbamoyl]-2-fluorophenyl]-3-[2-[1-[2-(2,6-dioxopiperidin-3-yl)-6-fluoro-1,3-dioxoisoindol-5-yl]azetidin-3-yl]-2,7-diazaspiro[3.5]nonan-7-yl]imidazo[1,5-a]pyrazin-6-yl]-4-chloro-2-pyridinyl]-4-[8-amino-3-[2-[[1-[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-5-yl]azetidin-3-yl]methyl]-2,7-diazaspiro[3.5]nonan-7-yl]imidazo[1,5-a]pyrazin-1-yl]-3-fluorobenzamide

N-[6-[8-amino-1-[4-[(4-chloro-2-pyridinyl)carbamoyl]-2-fluorophenyl]-3-[2-[1-[2-(2,6-dioxopiperidin-3-yl)-6-fluoro-1,3-dioxoisoindol-5-yl]azetidin-3-yl]-2,7-diazaspiro[3.5]nonan-7-yl]imidazo[1,5-a]pyrazin-6-yl]-4-chloro-2-pyridinyl]-4-[8-amino-3-[2-[[1-[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-5-yl]azetidin-3-yl]methyl]-2,7-diazaspiro[3.5]nonan-7-yl]imidazo[1,5-a]pyrazin-1-yl]-3-fluorobenzamide (PubChem CID 167206743) has the molecular formula C83H73Cl2F3N22O10 and a molecular weight of 1666.54 g/mol. Its IUPAC name is N-[6-[8-amino-1-[4-[(4-chloro-2-pyridinyl)carbamoyl]-2-fluorophenyl]-3-[2-[1-[2-(2,6-dioxopiperidin-3-yl)-6-fluoro-1,3-dioxoisoindol-5-yl]azetidin-3-yl]-2,7-diazaspiro[3.5]nonan-7-yl]imidazo[1,5-a]pyrazin-6-yl]-4-chloro-2-pyridinyl]-4-[8-amino-3-[2-[[1-[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-5-yl]azetidin-3-yl]methyl]-2,7-diazaspiro[3.5]nonan-7-yl]imidazo[1,5-a]pyrazin-1-yl]-3-fluorobenzamide.

Molecular Properties

• Compound Name: N-[6-[8-amino-1-[4-[(4-chloro-2-pyridinyl)carbamoyl]-2-fluorophenyl]-3-[2-[1-[2-(2,6-dioxopiperidin-3-yl)-6-fluoro-1,3-dioxoisoindol-5-yl]azetidin-3-yl]-2,7-diazaspiro[3.5]nonan-7-yl]imidazo[1,5-a]pyrazin-6-yl]-4-chloro-2-pyridinyl]-4-[8-amino-3-[2-[[1-[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-5-yl]azetidin-3-yl]methyl]-2,7-diazaspiro[3.5]nonan-7-yl]imidazo[1,5-a]pyrazin-1-yl]-3-fluorobenzamide
• PubChem CID: 167206743
• Molecular Formula: C83H73Cl2F3N22O10
• Molecular Weight: 1666.54 g/mol
• Exact Mass: 1664.52
• IUPAC Name: N-[6-[8-amino-1-[4-[(4-chloro-2-pyridinyl)carbamoyl]-2-fluorophenyl]-3-[2-[1-[2-(2,6-dioxopiperidin-3-yl)-6-fluoro-1,3-dioxoisoindol-5-yl]azetidin-3-yl]-2,7-diazaspiro[3.5]nonan-7-yl]imidazo[1,5-a]pyrazin-6-yl]-4-chloro-2-pyridinyl]-4-[8-amino-3-[2-[[1-[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-5-yl]azetidin-3-yl]methyl]-2,7-diazaspiro[3.5]nonan-7-yl]imidazo[1,5-a]pyrazin-1-yl]-3-fluorobenzamide
• SMILES: Nc1nccn2c(N3CCC4(CC3)CN(CC3CN(c5ccc6c(c5)C(=O)N(C5CCC(=O)NC5=O)C6=O)C3)C4)nc(-c3ccc(C(=O)Nc4cc(Cl)cc(-c5cn6c(N7CCC8(CC7)CN(C7CN(c9cc%10c(cc9F)C(=O)N(C9CCC(=O)NC9=O)C%10=O)C7)C8)nc(-c7ccc(C(=O)Nc8cc(Cl)ccn8)cc7F)c6c(N)n5)n4)cc3F)c12
• InChI: InChI=1S/C83H73Cl2F3N22O10/c84-44-11-16-91-62(26-44)95-72(113)42-1-5-50(55(87)23-42)67-69-71(90)94-58(36-108(69)81(100-67)103-20-14-83(15-21-103)39-106(40-83)47-34-105(35-47)61-30-53-52(29-56(61)88)78(119)110(79(53)120)60-8-10-65(112)98-75(60)116)57-25-45(85)27-63(93-57)96-73(114)43-2-4-49(54(86)24-43)66-68-70(89)92-17-22-107(68)80(99-66)102-18-12-82(13-19-102)37-101(38-82)31-41-32-104(33-41)46-3-6-48-51(28-46)77(118)109(76(48)117)59-7-9-64(111)97-74(59)115/h1-6,11,16-17,22-30,36,41,47,59-60H,7-10,12-15,18-21,31-35,37-40H2,(H2,89,92)(H2,90,94)(H,91,95,113)(H,93,96,114)(H,97,111,115)(H,98,112,116)
• InChIKey: DZMJZANOXMTCMZ-UHFFFAOYSA-N
• XLogP: 7.59
• TPSA: 382.94 Ų
• H-Bond Donors: 6
• H-Bond Acceptors: 26
• Rotatable Bonds: 16
• Heavy Atoms: 120
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	1666.54
LogP ≤ 5	7.59
H-Bond Donors ≤ 5	6
H-Bond Acceptors ≤ 10	26

Computed Properties (RDKit)

• Structural Alerts: {'alert_name': 'phthalimide', 'substructure': 'N/A'}

Frequently Asked Questions

What is the IUPAC name of N-[6-[8-amino-1-[4-[(4-chloro-2-pyridinyl)carbamoyl]-2-fluorophenyl]-3-[2-[1-[2-(2,6-dioxopiperidin-3-yl)-6-fluoro-1,3-dioxoisoindol-5-yl]azetidin-3-yl]-2,7-diazaspiro[3.5]nonan-7-yl]imidazo[1,5-a]pyrazin-6-yl]-4-chloro-2-pyridinyl]-4-[8-amino-3-[2-[[1-[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-5-yl]azetidin-3-yl]methyl]-2,7-diazaspiro[3.5]nonan-7-yl]imidazo[1,5-a]pyrazin-1-yl]-3-fluorobenzamide?

The IUPAC name of N-[6-[8-amino-1-[4-[(4-chloro-2-pyridinyl)carbamoyl]-2-fluorophenyl]-3-[2-[1-[2-(2,6-dioxopiperidin-3-yl)-6-fluoro-1,3-dioxoisoindol-5-yl]azetidin-3-yl]-2,7-diazaspiro[3.5]nonan-7-yl]imidazo[1,5-a]pyrazin-6-yl]-4-chloro-2-pyridinyl]-4-[8-amino-3-[2-[[1-[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-5-yl]azetidin-3-yl]methyl]-2,7-diazaspiro[3.5]nonan-7-yl]imidazo[1,5-a]pyrazin-1-yl]-3-fluorobenzamide (CID 167206743) is N-[6-[8-amino-1-[4-[(4-chloro-2-pyridinyl)carbamoyl]-2-fluorophenyl]-3-[2-[1-[2-(2,6-dioxopiperidin-3-yl)-6-fluoro-1,3-dioxoisoindol-5-yl]azetidin-3-yl]-2,7-diazaspiro[3.5]nonan-7-yl]imidazo[1,5-a]pyrazin-6-yl]-4-chloro-2-pyridinyl]-4-[8-amino-3-[2-[[1-[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-5-yl]azetidin-3-yl]methyl]-2,7-diazaspiro[3.5]nonan-7-yl]imidazo[1,5-a]pyrazin-1-yl]-3-fluorobenzamide.

What is the SMILES notation for N-[6-[8-amino-1-[4-[(4-chloro-2-pyridinyl)carbamoyl]-2-fluorophenyl]-3-[2-[1-[2-(2,6-dioxopiperidin-3-yl)-6-fluoro-1,3-dioxoisoindol-5-yl]azetidin-3-yl]-2,7-diazaspiro[3.5]nonan-7-yl]imidazo[1,5-a]pyrazin-6-yl]-4-chloro-2-pyridinyl]-4-[8-amino-3-[2-[[1-[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-5-yl]azetidin-3-yl]methyl]-2,7-diazaspiro[3.5]nonan-7-yl]imidazo[1,5-a]pyrazin-1-yl]-3-fluorobenzamide?

The canonical SMILES for N-[6-[8-amino-1-[4-[(4-chloro-2-pyridinyl)carbamoyl]-2-fluorophenyl]-3-[2-[1-[2-(2,6-dioxopiperidin-3-yl)-6-fluoro-1,3-dioxoisoindol-5-yl]azetidin-3-yl]-2,7-diazaspiro[3.5]nonan-7-yl]imidazo[1,5-a]pyrazin-6-yl]-4-chloro-2-pyridinyl]-4-[8-amino-3-[2-[[1-[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-5-yl]azetidin-3-yl]methyl]-2,7-diazaspiro[3.5]nonan-7-yl]imidazo[1,5-a]pyrazin-1-yl]-3-fluorobenzamide is Nc1nccn2c(N3CCC4(CC3)CN(CC3CN(c5ccc6c(c5)C(=O)N(C5CCC(=O)NC5=O)C6=O)C3)C4)nc(-c3ccc(C(=O)Nc4cc(Cl)cc(-c5cn6c(N7CCC8(CC7)CN(C7CN(c9cc%10c(cc9F)C(=O)N(C9CCC(=O)NC9=O)C%10=O)C7)C8)nc(-c7ccc(C(=O)Nc8cc(Cl)ccn8)cc7F)c6c(N)n5)n4)cc3F)c12.

What is the InChIKey of N-[6-[8-amino-1-[4-[(4-chloro-2-pyridinyl)carbamoyl]-2-fluorophenyl]-3-[2-[1-[2-(2,6-dioxopiperidin-3-yl)-6-fluoro-1,3-dioxoisoindol-5-yl]azetidin-3-yl]-2,7-diazaspiro[3.5]nonan-7-yl]imidazo[1,5-a]pyrazin-6-yl]-4-chloro-2-pyridinyl]-4-[8-amino-3-[2-[[1-[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-5-yl]azetidin-3-yl]methyl]-2,7-diazaspiro[3.5]nonan-7-yl]imidazo[1,5-a]pyrazin-1-yl]-3-fluorobenzamide?

The InChIKey is DZMJZANOXMTCMZ-UHFFFAOYSA-N. The full InChI is InChI=1S/C83H73Cl2F3N22O10/c84-44-11-16-91-62(26-44)95-72(113)42-1-5-50(55(87)23-42)67-69-71(90)94-58(36-108(69)81(100-67)103-20-14-83(15-21-103)39-106(40-83)47-34-105(35-47)61-30-53-52(29-56(61)88)78(119)110(79(53)120)60-8-10-65(112)98-75(60)116)57-25-45(85)27-63(93-57)96-73(114)43-2-4-49(54(86)24-43)66-68-70(89)92-17-22-107(68)80(99-66)102-18-12-82(13-19-102)37-101(38-82)31-41-32-104(33-41)46-3-6-48-51(28-46)77(118)109(76(48)117)59-7-9-64(111)97-74(59)115/h1-6,11,16-17,22-30,36,41,47,59-60H,7-10,12-15,18-21,31-35,37-40H2,(H2,89,92)(H2,90,94)(H,91,95,113)(H,93,96,114)(H,97,111,115)(H,98,112,116).

What are the key properties of N-[6-[8-amino-1-[4-[(4-chloro-2-pyridinyl)carbamoyl]-2-fluorophenyl]-3-[2-[1-[2-(2,6-dioxopiperidin-3-yl)-6-fluoro-1,3-dioxoisoindol-5-yl]azetidin-3-yl]-2,7-diazaspiro[3.5]nonan-7-yl]imidazo[1,5-a]pyrazin-6-yl]-4-chloro-2-pyridinyl]-4-[8-amino-3-[2-[[1-[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-5-yl]azetidin-3-yl]methyl]-2,7-diazaspiro[3.5]nonan-7-yl]imidazo[1,5-a]pyrazin-1-yl]-3-fluorobenzamide?

N-[6-[8-amino-1-[4-[(4-chloro-2-pyridinyl)carbamoyl]-2-fluorophenyl]-3-[2-[1-[2-(2,6-dioxopiperidin-3-yl)-6-fluoro-1,3-dioxoisoindol-5-yl]azetidin-3-yl]-2,7-diazaspiro[3.5]nonan-7-yl]imidazo[1,5-a]pyrazin-6-yl]-4-chloro-2-pyridinyl]-4-[8-amino-3-[2-[[1-[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-5-yl]azetidin-3-yl]methyl]-2,7-diazaspiro[3.5]nonan-7-yl]imidazo[1,5-a]pyrazin-1-yl]-3-fluorobenzamide has a molecular weight of 1666.54 g/mol, XLogP of 7.59, 16 rotatable bonds, 6 hydrogen bond donors, and 26 hydrogen bond acceptors.

Where does this data come from?

All data for N-[6-[8-amino-1-[4-[(4-chloro-2-pyridinyl)carbamoyl]-2-fluorophenyl]-3-[2-[1-[2-(2,6-dioxopiperidin-3-yl)-6-fluoro-1,3-dioxoisoindol-5-yl]azetidin-3-yl]-2,7-diazaspiro[3.5]nonan-7-yl]imidazo[1,5-a]pyrazin-6-yl]-4-chloro-2-pyridinyl]-4-[8-amino-3-[2-[[1-[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-5-yl]azetidin-3-yl]methyl]-2,7-diazaspiro[3.5]nonan-7-yl]imidazo[1,5-a]pyrazin-1-yl]-3-fluorobenzamide is sourced from PubChem (CID 167206743), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).