6-[2,6-difluoro-3-[(5-fluoro-2-methoxy-3-pyridinyl)sulfonylamino]phenyl]-7-fluoro-2H-indazole-3-carboxamide

C20H13F4N5O4S — CID 167251058

IUPAC6-[2,6-difluoro-3-[(5-fluoro-2-methoxy-3-pyridinyl)sulfonylamino]phenyl]-7-fluoro-2H-indazole-3-carboxamide
SMILESCOc1ncc(F)cc1S(=O)(=O)Nc1ccc(F)c(-c2ccc3c(C(N)=O)[nH]nc3c2F)c1F
InChIInChI=1S/C20H13F4N5O4S/c1-33-20-13(6-8(21)7-26-20)34(31,32)29-12-5-4-11(22)14(16(12)24)9-2-3-10-17(15(9)23)27-28-18(10)19(25)30/h2-7,29H,1H3,(H2,25,30)(H,27,28)
InChIKeyQJWPKVMFNMKVCY-UHFFFAOYSA-N
MW495.41 g/mol
LogP3.09
Rot. Bonds6

About 6-[2,6-difluoro-3-[(5-fluoro-2-methoxy-3-pyridinyl)sulfonylamino]phenyl]-7-fluoro-2H-indazole-3-carboxamide

6-[2,6-difluoro-3-[(5-fluoro-2-methoxy-3-pyridinyl)sulfonylamino]phenyl]-7-fluoro-2H-indazole-3-carboxamide (PubChem CID 167251058) has the molecular formula C20H13F4N5O4S and a molecular weight of 495.41 g/mol. Its IUPAC name is 6-[2,6-difluoro-3-[(5-fluoro-2-methoxy-3-pyridinyl)sulfonylamino]phenyl]-7-fluoro-2H-indazole-3-carboxamide.

Molecular Properties

Compound Name6-[2,6-difluoro-3-[(5-fluoro-2-methoxy-3-pyridinyl)sulfonylamino]phenyl]-7-fluoro-2H-indazole-3-carboxamide
PubChem CID167251058
Molecular FormulaC20H13F4N5O4S
Molecular Weight495.41 g/mol
Exact Mass495.06
IUPAC Name6-[2,6-difluoro-3-[(5-fluoro-2-methoxy-3-pyridinyl)sulfonylamino]phenyl]-7-fluoro-2H-indazole-3-carboxamide
SMILESCOc1ncc(F)cc1S(=O)(=O)Nc1ccc(F)c(-c2ccc3c(C(N)=O)[nH]nc3c2F)c1F
InChIInChI=1S/C20H13F4N5O4S/c1-33-20-13(6-8(21)7-26-20)34(31,32)29-12-5-4-11(22)14(16(12)24)9-2-3-10-17(15(9)23)27-28-18(10)19(25)30/h2-7,29H,1H3,(H2,25,30)(H,27,28)
InChIKeyQJWPKVMFNMKVCY-UHFFFAOYSA-N
XLogP3.09
TPSA140.06 Ų
H-Bond Donors3
H-Bond Acceptors6
Rotatable Bonds6
Heavy Atoms34
Complexity—

Lipinski Rule of Five

Passes Rule of Five

RuleValue
MW ≤ 500495.41
LogP ≤ 53.09
H-Bond Donors ≤ 53
H-Bond Acceptors ≤ 106

Analyze 6-[2,6-difluoro-3-[(5-fluoro-2-methoxy-3-pyridinyl)sulfonylamino]phenyl]-7-fluoro-2H-indazole-3-carboxamide with MolForge

Explore ADMET properties, 3D molecular structure, drug-likeness score, and discover similar compounds using our AI-powered platform.

Launch Full Analysis

Related Compounds

6-[3-[(5-chloro-2-methoxy-3-pyridinyl)sulfonylamino]-2,6-difluorophenyl]-7-fluoro-2H-indazole-3-carboxamide
CID 167250860
6-[2,6-difluoro-3-[(5-fluoro-2-methyl-3-pyridinyl)sulfonylamino]phenyl]-7-fluoro-2H-indazole-3-carboxamide
CID 167251453
6-[2,6-difluoro-3-[(5-fluoro-2-methoxy-3-pyridinyl)sulfonylamino]phenyl]-7-fluoro-N-piperidin-4-yl-2H-indazole-3-carboxamide
CID 167251073
6-[2,6-difluoro-3-[(5-fluoro-2-methoxy-3-pyridinyl)sulfonylamino]phenyl]-7-fluoro-N-[3-hydroxy-2-(hydroxymethyl)propyl]-2H-indazole-3-carboxamide
CID 167251230
6-[2,6-difluoro-3-[(5-fluoro-2-methoxy-3-pyridinyl)sulfonylamino]phenyl]-7-fluoro-N-(1-methylpyrazol-4-yl)-2H-indazole-3-carboxamide
CID 167251195
6-[2,6-difluoro-3-[(5-fluoro-2-methoxy-3-pyridinyl)sulfonylamino]phenyl]-N-[3-(dimethylamino)propyl]-7-fluoro-2H-indazole-3-carboxamide
CID 167251218
6-[3-[(5-chloro-2-methoxy-3-pyridinyl)sulfonylamino]-2,6-difluorophenyl]-N-[2-(dimethylamino)ethyl]-7-fluoro-2H-indazole-3-carboxamide
CID 167250865
6-[3-[(5-chloro-2-methoxy-3-pyridinyl)sulfonylamino]-2,6-difluorophenyl]-7-fluoro-N-[2-(2-oxopyrrolidin-1-yl)ethyl]-2H-indazole-3-carboxamide
CID 155193745
5-chloro-N-[2,4-difluoro-3-[7-fluoro-3-[(2-hydroxyethylamino)methyl]-2H-indazol-6-yl]phenyl]-2-methoxypyridine-3-sulfonamide
CID 167251027
6-[2,6-difluoro-3-[(5-fluoro-2-methoxy-3-pyridinyl)sulfonylmethyl]phenyl]-N-[3-(dimethylamino)propyl]-7-fluoro-2H-indazole-3-carboxamide
CID 167549858
methyl 6-[3-[(5-chloro-2-methoxy-3-pyridinyl)sulfonylmethyl]-2,6-difluorophenyl]-7-fluoro-2H-indazole-3-carboxylate
CID 167568213
N-[3-(3-amino-1H-indazol-6-yl)-2,4-difluorophenyl]-5-chloro-2-methoxypyridine-3-sulfonamide
CID 156833302

Frequently Asked Questions

What is the IUPAC name of 6-[2,6-difluoro-3-[(5-fluoro-2-methoxy-3-pyridinyl)sulfonylamino]phenyl]-7-fluoro-2H-indazole-3-carboxamide?
The IUPAC name of 6-[2,6-difluoro-3-[(5-fluoro-2-methoxy-3-pyridinyl)sulfonylamino]phenyl]-7-fluoro-2H-indazole-3-carboxamide (CID 167251058) is 6-[2,6-difluoro-3-[(5-fluoro-2-methoxy-3-pyridinyl)sulfonylamino]phenyl]-7-fluoro-2H-indazole-3-carboxamide.
What is the SMILES notation for 6-[2,6-difluoro-3-[(5-fluoro-2-methoxy-3-pyridinyl)sulfonylamino]phenyl]-7-fluoro-2H-indazole-3-carboxamide?
The canonical SMILES for 6-[2,6-difluoro-3-[(5-fluoro-2-methoxy-3-pyridinyl)sulfonylamino]phenyl]-7-fluoro-2H-indazole-3-carboxamide is COc1ncc(F)cc1S(=O)(=O)Nc1ccc(F)c(-c2ccc3c(C(N)=O)[nH]nc3c2F)c1F.
What is the InChIKey of 6-[2,6-difluoro-3-[(5-fluoro-2-methoxy-3-pyridinyl)sulfonylamino]phenyl]-7-fluoro-2H-indazole-3-carboxamide?
The InChIKey is QJWPKVMFNMKVCY-UHFFFAOYSA-N. The full InChI is InChI=1S/C20H13F4N5O4S/c1-33-20-13(6-8(21)7-26-20)34(31,32)29-12-5-4-11(22)14(16(12)24)9-2-3-10-17(15(9)23)27-28-18(10)19(25)30/h2-7,29H,1H3,(H2,25,30)(H,27,28).
What are the key properties of 6-[2,6-difluoro-3-[(5-fluoro-2-methoxy-3-pyridinyl)sulfonylamino]phenyl]-7-fluoro-2H-indazole-3-carboxamide?
6-[2,6-difluoro-3-[(5-fluoro-2-methoxy-3-pyridinyl)sulfonylamino]phenyl]-7-fluoro-2H-indazole-3-carboxamide has a molecular weight of 495.41 g/mol, XLogP of 3.09, 6 rotatable bonds, 3 hydrogen bond donors, and 6 hydrogen bond acceptors.
Where does this data come from?
All data for 6-[2,6-difluoro-3-[(5-fluoro-2-methoxy-3-pyridinyl)sulfonylamino]phenyl]-7-fluoro-2H-indazole-3-carboxamide is sourced from PubChem (CID 167251058), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).