About 2-[6-chloro-1-(3,3-difluorocyclobutyl)oxy-2,7-naphthyridin-4-yl]propan-2-amine
2-[6-chloro-1-(3,3-difluorocyclobutyl)oxy-2,7-naphthyridin-4-yl]propan-2-amine (PubChem CID 167261428) has the molecular formula C15H16ClF2N3O
and a molecular weight of 327.76 g/mol. Its IUPAC name is 2-[6-chloro-1-(3,3-difluorocyclobutyl)oxy-2,7-naphthyridin-4-yl]propan-2-amine.
Molecular Properties
| Compound Name | 2-[6-chloro-1-(3,3-difluorocyclobutyl)oxy-2,7-naphthyridin-4-yl]propan-2-amine |
| PubChem CID | 167261428 |
| Molecular Formula | C15H16ClF2N3O |
| Molecular Weight | 327.76 g/mol |
| Exact Mass | 327.09 |
| IUPAC Name | 2-[6-chloro-1-(3,3-difluorocyclobutyl)oxy-2,7-naphthyridin-4-yl]propan-2-amine |
| SMILES | CC(C)(N)c1cnc(OC2CC(F)(F)C2)c2cnc(Cl)cc12 |
| InChI | InChI=1S/C15H16ClF2N3O/c1-14(2,19)11-7-21-13(22-8-4-15(17,18)5-8)10-6-20-12(16)3-9(10)11/h3,6-8H,4-5,19H2,1-2H3 |
| InChIKey | XHLBEZQZUNQRMX-UHFFFAOYSA-N |
| XLogP | 3.65 |
| TPSA | 61.03 Ų |
| H-Bond Donors | 1 |
| H-Bond Acceptors | 4 |
| Rotatable Bonds | 3 |
| Heavy Atoms | 22 |
| Complexity | — |
Lipinski Rule of Five
Passes Rule of Five
| Rule | Value |
| MW ≤ 500 | 327.76 |
| LogP ≤ 5 | 3.65 |
| H-Bond Donors ≤ 5 | 1 |
| H-Bond Acceptors ≤ 10 | 4 |
Computed Properties (RDKit)
| Structural Alerts | {'alert_name': '2-halo_pyridine', 'substructure': 'N/A'} |
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Frequently Asked Questions
What is the IUPAC name of 2-[6-chloro-1-(3,3-difluorocyclobutyl)oxy-2,7-naphthyridin-4-yl]propan-2-amine?
The IUPAC name of 2-[6-chloro-1-(3,3-difluorocyclobutyl)oxy-2,7-naphthyridin-4-yl]propan-2-amine (CID 167261428) is 2-[6-chloro-1-(3,3-difluorocyclobutyl)oxy-2,7-naphthyridin-4-yl]propan-2-amine.
What is the SMILES notation for 2-[6-chloro-1-(3,3-difluorocyclobutyl)oxy-2,7-naphthyridin-4-yl]propan-2-amine?
The canonical SMILES for 2-[6-chloro-1-(3,3-difluorocyclobutyl)oxy-2,7-naphthyridin-4-yl]propan-2-amine is CC(C)(N)c1cnc(OC2CC(F)(F)C2)c2cnc(Cl)cc12.
What is the InChIKey of 2-[6-chloro-1-(3,3-difluorocyclobutyl)oxy-2,7-naphthyridin-4-yl]propan-2-amine?
The InChIKey is XHLBEZQZUNQRMX-UHFFFAOYSA-N. The full InChI is InChI=1S/C15H16ClF2N3O/c1-14(2,19)11-7-21-13(22-8-4-15(17,18)5-8)10-6-20-12(16)3-9(10)11/h3,6-8H,4-5,19H2,1-2H3.
What are the key properties of 2-[6-chloro-1-(3,3-difluorocyclobutyl)oxy-2,7-naphthyridin-4-yl]propan-2-amine?
2-[6-chloro-1-(3,3-difluorocyclobutyl)oxy-2,7-naphthyridin-4-yl]propan-2-amine has a molecular weight of 327.76 g/mol, XLogP of 3.65, 3 rotatable bonds, 1 hydrogen bond donors, and 4 hydrogen bond acceptors.
Where does this data come from?
All data for 2-[6-chloro-1-(3,3-difluorocyclobutyl)oxy-2,7-naphthyridin-4-yl]propan-2-amine is sourced from PubChem (CID 167261428), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).