About (5S)-1-[(2R)-1-(benzylamino)-3-(2-fluorophenyl)propan-2-yl]-5-tert-butyl-4-[2-(3-methoxyphenyl)ethyl]piperazine-2,3-dione
(5S)-1-[(2R)-1-(benzylamino)-3-(2-fluorophenyl)propan-2-yl]-5-tert-butyl-4-[2-(3-methoxyphenyl)ethyl]piperazine-2,3-dione (PubChem CID 16745334) has the molecular formula C33H40FN3O3
and a molecular weight of 545.70 g/mol. Its IUPAC name is (5S)-1-[(2R)-1-(benzylamino)-3-(2-fluorophenyl)propan-2-yl]-5-tert-butyl-4-[2-(3-methoxyphenyl)ethyl]piperazine-2,3-dione.
Molecular Properties
| Compound Name | (5S)-1-[(2R)-1-(benzylamino)-3-(2-fluorophenyl)propan-2-yl]-5-tert-butyl-4-[2-(3-methoxyphenyl)ethyl]piperazine-2,3-dione |
| PubChem CID | 16745334 |
| Molecular Formula | C33H40FN3O3 |
| Molecular Weight | 545.70 g/mol |
| Exact Mass | 545.31 |
| IUPAC Name | (5S)-1-[(2R)-1-(benzylamino)-3-(2-fluorophenyl)propan-2-yl]-5-tert-butyl-4-[2-(3-methoxyphenyl)ethyl]piperazine-2,3-dione |
| SMILES | COc1cccc(CCN2C(=O)C(=O)N([C@@H](CNCc3ccccc3)Cc3ccccc3F)C[C@@H]2C(C)(C)C)c1 |
| InChI | InChI=1S/C33H40FN3O3/c1-33(2,3)30-23-37(32(39)31(38)36(30)18-17-24-13-10-15-28(19-24)40-4)27(20-26-14-8-9-16-29(26)34)22-35-21-25-11-6-5-7-12-25/h5-16,19,27,30,35H,17-18,20-23H2,1-4H3/t27-,30-/m1/s1 |
| InChIKey | DWLCVAFWNVGXHW-POURPWNDSA-N |
| XLogP | 4.86 |
| TPSA | 61.88 Ų |
| H-Bond Donors | 1 |
| H-Bond Acceptors | 4 |
| Rotatable Bonds | 11 |
| Heavy Atoms | 40 |
| Complexity | — |
Lipinski Rule of Five
1 violation
| Rule | Value |
| MW ≤ 500 | 545.70 |
| LogP ≤ 5 | 4.86 |
| H-Bond Donors ≤ 5 | 1 |
| H-Bond Acceptors ≤ 10 | 4 |
Computed Properties (RDKit)
| Structural Alerts | {'alert_name': 'diketo_group', 'substructure': 'N/A'} |
|---|
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Frequently Asked Questions
What is the IUPAC name of (5S)-1-[(2R)-1-(benzylamino)-3-(2-fluorophenyl)propan-2-yl]-5-tert-butyl-4-[2-(3-methoxyphenyl)ethyl]piperazine-2,3-dione?
The IUPAC name of (5S)-1-[(2R)-1-(benzylamino)-3-(2-fluorophenyl)propan-2-yl]-5-tert-butyl-4-[2-(3-methoxyphenyl)ethyl]piperazine-2,3-dione (CID 16745334) is (5S)-1-[(2R)-1-(benzylamino)-3-(2-fluorophenyl)propan-2-yl]-5-tert-butyl-4-[2-(3-methoxyphenyl)ethyl]piperazine-2,3-dione.
What is the SMILES notation for (5S)-1-[(2R)-1-(benzylamino)-3-(2-fluorophenyl)propan-2-yl]-5-tert-butyl-4-[2-(3-methoxyphenyl)ethyl]piperazine-2,3-dione?
The canonical SMILES for (5S)-1-[(2R)-1-(benzylamino)-3-(2-fluorophenyl)propan-2-yl]-5-tert-butyl-4-[2-(3-methoxyphenyl)ethyl]piperazine-2,3-dione is COc1cccc(CCN2C(=O)C(=O)N([C@@H](CNCc3ccccc3)Cc3ccccc3F)C[C@@H]2C(C)(C)C)c1.
What is the InChIKey of (5S)-1-[(2R)-1-(benzylamino)-3-(2-fluorophenyl)propan-2-yl]-5-tert-butyl-4-[2-(3-methoxyphenyl)ethyl]piperazine-2,3-dione?
The InChIKey is DWLCVAFWNVGXHW-POURPWNDSA-N. The full InChI is InChI=1S/C33H40FN3O3/c1-33(2,3)30-23-37(32(39)31(38)36(30)18-17-24-13-10-15-28(19-24)40-4)27(20-26-14-8-9-16-29(26)34)22-35-21-25-11-6-5-7-12-25/h5-16,19,27,30,35H,17-18,20-23H2,1-4H3/t27-,30-/m1/s1.
What are the key properties of (5S)-1-[(2R)-1-(benzylamino)-3-(2-fluorophenyl)propan-2-yl]-5-tert-butyl-4-[2-(3-methoxyphenyl)ethyl]piperazine-2,3-dione?
(5S)-1-[(2R)-1-(benzylamino)-3-(2-fluorophenyl)propan-2-yl]-5-tert-butyl-4-[2-(3-methoxyphenyl)ethyl]piperazine-2,3-dione has a molecular weight of 545.70 g/mol, XLogP of 4.86, 11 rotatable bonds, 1 hydrogen bond donors, and 4 hydrogen bond acceptors.
Where does this data come from?
All data for (5S)-1-[(2R)-1-(benzylamino)-3-(2-fluorophenyl)propan-2-yl]-5-tert-butyl-4-[2-(3-methoxyphenyl)ethyl]piperazine-2,3-dione is sourced from PubChem (CID 16745334), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).