N-[5-[[5-(trifluoromethyl)-2,3-dihydro-1H-inden-2-yl]oxy]-1H-indol-3-yl]acetamide

C20H17F3N2O2 — CID 167468115

IUPACN-[5-[[5-(trifluoromethyl)-2,3-dihydro-1H-inden-2-yl]oxy]-1H-indol-3-yl]acetamide
SMILESCC(=O)Nc1c[nH]c2ccc(OC3Cc4ccc(C(F)(F)F)cc4C3)cc12
InChIInChI=1S/C20H17F3N2O2/c1-11(26)25-19-10-24-18-5-4-15(9-17(18)19)27-16-7-12-2-3-14(20(21,22)23)6-13(12)8-16/h2-6,9-10,16,24H,7-8H2,1H3,(H,25,26)
InChIKeyIMHOWHGJQNGRTO-UHFFFAOYSA-N
MW374.36 g/mol
LogP4.69
Rot. Bonds3

About N-[5-[[5-(trifluoromethyl)-2,3-dihydro-1H-inden-2-yl]oxy]-1H-indol-3-yl]acetamide

N-[5-[[5-(trifluoromethyl)-2,3-dihydro-1H-inden-2-yl]oxy]-1H-indol-3-yl]acetamide (PubChem CID 167468115) has the molecular formula C20H17F3N2O2 and a molecular weight of 374.36 g/mol. Its IUPAC name is N-[5-[[5-(trifluoromethyl)-2,3-dihydro-1H-inden-2-yl]oxy]-1H-indol-3-yl]acetamide.

Molecular Properties

Compound NameN-[5-[[5-(trifluoromethyl)-2,3-dihydro-1H-inden-2-yl]oxy]-1H-indol-3-yl]acetamide
PubChem CID167468115
Molecular FormulaC20H17F3N2O2
Molecular Weight374.36 g/mol
Exact Mass374.12
IUPAC NameN-[5-[[5-(trifluoromethyl)-2,3-dihydro-1H-inden-2-yl]oxy]-1H-indol-3-yl]acetamide
SMILESCC(=O)Nc1c[nH]c2ccc(OC3Cc4ccc(C(F)(F)F)cc4C3)cc12
InChIInChI=1S/C20H17F3N2O2/c1-11(26)25-19-10-24-18-5-4-15(9-17(18)19)27-16-7-12-2-3-14(20(21,22)23)6-13(12)8-16/h2-6,9-10,16,24H,7-8H2,1H3,(H,25,26)
InChIKeyIMHOWHGJQNGRTO-UHFFFAOYSA-N
XLogP4.69
TPSA54.12 Ų
H-Bond Donors2
H-Bond Acceptors2
Rotatable Bonds3
Heavy Atoms27
Complexity—

Lipinski Rule of Five

Passes Rule of Five

RuleValue
MW ≤ 500374.36
LogP ≤ 54.69
H-Bond Donors ≤ 52
H-Bond Acceptors ≤ 102

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Related Compounds

N-(5-cyclobutyloxy-1H-indol-3-yl)cyclopropanecarboxamide;trifluoromethylbenzene
CID 167467905
N-[5-[[4-(trifluoromethyl)phenyl]methyl]-1H-indol-3-yl]acetamide
CID 167468240
2,2-difluoro-N-[5-[3-[4-(trifluoromethyl)phenyl]cyclobutyl]oxy-1H-indol-3-yl]cyclopropane-1-carboxamide
CID 167467491
N-[5-[3-[4-(trifluoromethyl)phenyl]cyclobutyl]oxy-1H-indol-3-yl]-3-oxabicyclo[3.1.0]hexane-6-carboxamide
CID 168986833
N-[5-[2-hydroxy-3-[4-(trifluoromethyl)phenyl]propyl]-1H-indol-3-yl]acetamide
CID 167467546
3-methyl-N-[5-[2-[4-(trifluoromethyl)phenyl]ethoxy]-1H-indol-3-yl]cyclobutane-1-carboxamide
CID 167467588
N-(5-cyclobutyloxy-1H-indol-3-yl)-1-fluorocyclopropane-1-carboxamide
CID 167468016
3,3-difluoro-N-[5-[[4-(trifluoromethyl)phenyl]methoxy]-1H-indol-3-yl]cyclobutane-1-carboxamide
CID 167468164
trans-(1S,2S)-2-methyl-N-[5-[2-[4-(trifluoromethyl)phenoxy]ethyl]-1H-indol-3-yl]cyclopropane-1-carboxamide
CID 167467793
N-[5-[3-(4,4-difluoropiperidin-1-yl)-2,2-difluoropropoxy]-1H-indol-3-yl]acetamide
CID 167467458
4-methyl-N-[5-[[4-(trifluoromethyl)phenyl]methoxy]-1H-indol-3-yl]bicyclo[2.1.1]hexane-2-carboxamide
CID 170059611
1-methyl-N-[5-[3-[6-(trifluoromethyl)-3-pyridinyl]cyclobutyl]oxy-1H-indol-3-yl]cyclopropane-1-carboxamide
CID 167467792

Frequently Asked Questions

What is the IUPAC name of N-[5-[[5-(trifluoromethyl)-2,3-dihydro-1H-inden-2-yl]oxy]-1H-indol-3-yl]acetamide?
The IUPAC name of N-[5-[[5-(trifluoromethyl)-2,3-dihydro-1H-inden-2-yl]oxy]-1H-indol-3-yl]acetamide (CID 167468115) is N-[5-[[5-(trifluoromethyl)-2,3-dihydro-1H-inden-2-yl]oxy]-1H-indol-3-yl]acetamide.
What is the SMILES notation for N-[5-[[5-(trifluoromethyl)-2,3-dihydro-1H-inden-2-yl]oxy]-1H-indol-3-yl]acetamide?
The canonical SMILES for N-[5-[[5-(trifluoromethyl)-2,3-dihydro-1H-inden-2-yl]oxy]-1H-indol-3-yl]acetamide is CC(=O)Nc1c[nH]c2ccc(OC3Cc4ccc(C(F)(F)F)cc4C3)cc12.
What is the InChIKey of N-[5-[[5-(trifluoromethyl)-2,3-dihydro-1H-inden-2-yl]oxy]-1H-indol-3-yl]acetamide?
The InChIKey is IMHOWHGJQNGRTO-UHFFFAOYSA-N. The full InChI is InChI=1S/C20H17F3N2O2/c1-11(26)25-19-10-24-18-5-4-15(9-17(18)19)27-16-7-12-2-3-14(20(21,22)23)6-13(12)8-16/h2-6,9-10,16,24H,7-8H2,1H3,(H,25,26).
What are the key properties of N-[5-[[5-(trifluoromethyl)-2,3-dihydro-1H-inden-2-yl]oxy]-1H-indol-3-yl]acetamide?
N-[5-[[5-(trifluoromethyl)-2,3-dihydro-1H-inden-2-yl]oxy]-1H-indol-3-yl]acetamide has a molecular weight of 374.36 g/mol, XLogP of 4.69, 3 rotatable bonds, 2 hydrogen bond donors, and 2 hydrogen bond acceptors.
Where does this data come from?
All data for N-[5-[[5-(trifluoromethyl)-2,3-dihydro-1H-inden-2-yl]oxy]-1H-indol-3-yl]acetamide is sourced from PubChem (CID 167468115), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).