N-(8-fluoro-2-methylimidazo[1,2-a]pyridin-6-yl)-2-methyl-4-[(3R)-3-propan-2-ylpiperazin-1-yl]indazole-7-carboxamide

C24H28FN7O — CID 167502208

IUPACN-(8-fluoro-2-methylimidazo[1,2-a]pyridin-6-yl)-2-methyl-4-[(3R)-3-propan-2-ylpiperazin-1-yl]indazole-7-carboxamide
SMILESCc1cn2cc(NC(=O)c3ccc(N4CCN[C@H](C(C)C)C4)c4cn(C)nc34)cc(F)c2n1
InChIInChI=1S/C24H28FN7O/c1-14(2)20-13-31(8-7-26-20)21-6-5-17(22-18(21)12-30(4)29-22)24(33)28-16-9-19(25)23-27-15(3)10-32(23)11-16/h5-6,9-12,14,20,26H,7-8,13H2,1-4H3,(H,28,33)/t20-/m0/s1
InChIKeyHIZPPRSXDDHYDZ-FQEVSTJZSA-N
MW449.53 g/mol
LogP3.36
Rot. Bonds4

About N-(8-fluoro-2-methylimidazo[1,2-a]pyridin-6-yl)-2-methyl-4-[(3R)-3-propan-2-ylpiperazin-1-yl]indazole-7-carboxamide

N-(8-fluoro-2-methylimidazo[1,2-a]pyridin-6-yl)-2-methyl-4-[(3R)-3-propan-2-ylpiperazin-1-yl]indazole-7-carboxamide (PubChem CID 167502208) has the molecular formula C24H28FN7O and a molecular weight of 449.53 g/mol. Its IUPAC name is N-(8-fluoro-2-methylimidazo[1,2-a]pyridin-6-yl)-2-methyl-4-[(3R)-3-propan-2-ylpiperazin-1-yl]indazole-7-carboxamide.

Molecular Properties

Compound NameN-(8-fluoro-2-methylimidazo[1,2-a]pyridin-6-yl)-2-methyl-4-[(3R)-3-propan-2-ylpiperazin-1-yl]indazole-7-carboxamide
PubChem CID167502208
Molecular FormulaC24H28FN7O
Molecular Weight449.53 g/mol
Exact Mass449.23
IUPAC NameN-(8-fluoro-2-methylimidazo[1,2-a]pyridin-6-yl)-2-methyl-4-[(3R)-3-propan-2-ylpiperazin-1-yl]indazole-7-carboxamide
SMILESCc1cn2cc(NC(=O)c3ccc(N4CCN[C@H](C(C)C)C4)c4cn(C)nc34)cc(F)c2n1
InChIInChI=1S/C24H28FN7O/c1-14(2)20-13-31(8-7-26-20)21-6-5-17(22-18(21)12-30(4)29-22)24(33)28-16-9-19(25)23-27-15(3)10-32(23)11-16/h5-6,9-12,14,20,26H,7-8,13H2,1-4H3,(H,28,33)/t20-/m0/s1
InChIKeyHIZPPRSXDDHYDZ-FQEVSTJZSA-N
XLogP3.36
TPSA79.49 Ų
H-Bond Donors2
H-Bond Acceptors7
Rotatable Bonds4
Heavy Atoms33
Complexity—

Lipinski Rule of Five

Passes Rule of Five

RuleValue
MW ≤ 500449.53
LogP ≤ 53.36
H-Bond Donors ≤ 52
H-Bond Acceptors ≤ 107

Analyze N-(8-fluoro-2-methylimidazo[1,2-a]pyridin-6-yl)-2-methyl-4-[(3R)-3-propan-2-ylpiperazin-1-yl]indazole-7-carboxamide with MolForge

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Related Compounds

4-[(3R)-3-aminopyrrolidin-1-yl]-N-(8-fluoro-2-methylimidazo[1,2-a]pyridin-6-yl)-2-methylindazole-7-carboxamide
CID 167501954
N-(8-fluoro-2-methylimidazo[1,2-a]pyridin-6-yl)-2-methyl-4-[(3R)-3-piperazin-1-ylpyrrolidin-1-yl]indazole-7-carboxamide
CID 167501070
N-(8-fluoro-2-methylimidazo[1,2-a]pyridin-6-yl)-2-methyl-4-(4-methylpiperazin-1-yl)indazole-7-carboxamide
CID 167501617
N-(8-fluoro-2-methylimidazo[1,2-a]pyridin-6-yl)-2-methyl-4-[3-[(propan-2-ylamino)methyl]pyrrolidin-1-yl]indazole-7-carboxamide
CID 167501564
N-(8-chloro-2-methylimidazo[1,2-a]pyridin-6-yl)-2-methyl-4-(3-methylpiperazin-1-yl)indazole-7-carboxamide
CID 166523450
4-[(3R)-3-(cyclobutylamino)pyrrolidin-1-yl]-N-(8-fluoro-2-methylimidazo[1,2-a]pyridin-6-yl)-2-methylindazole-7-carboxamide
CID 167502110
2-ethyl-N-(8-fluoro-2-methylimidazo[1,2-a]pyridin-6-yl)-4-[(3S,5R)-3-methyl-5-propan-2-ylpiperazin-1-yl]indazole-7-carboxamide
CID 167501435
4-(2,6-diazaspiro[3.3]heptan-2-yl)-N-(8-fluoro-2-methylimidazo[1,2-a]pyridin-6-yl)-2-methylindazole-7-carboxamide
CID 167502034
N-(8-fluoro-2-methylimidazo[1,2-a]pyridin-6-yl)-2-methyl-4-(6-methyl-3,5-dihydro-2H-pyrazin-4-yl)indazole-7-carboxamide
CID 167501845
4-[4-(ethylamino)piperidin-1-yl]-N-(8-fluoro-2-methylimidazo[1,2-a]pyridin-6-yl)-2-methylindazole-7-carboxamide
CID 167501002
N-(8-fluoro-2-methylimidazo[1,2-a]pyridin-6-yl)-2-methyl-4-(3-methylpiperazin-1-yl)pyrazolo[4,3-c]pyridine-7-carboxamide
CID 167501520
N-(8-fluoro-2-methylimidazo[1,2-a]pyridin-6-yl)-4-[(3R)-3-[(3-methoxycyclobutyl)amino]pyrrolidin-1-yl]-2-methylindazole-7-carboxamide
CID 167501548

Frequently Asked Questions

What is the IUPAC name of N-(8-fluoro-2-methylimidazo[1,2-a]pyridin-6-yl)-2-methyl-4-[(3R)-3-propan-2-ylpiperazin-1-yl]indazole-7-carboxamide?
The IUPAC name of N-(8-fluoro-2-methylimidazo[1,2-a]pyridin-6-yl)-2-methyl-4-[(3R)-3-propan-2-ylpiperazin-1-yl]indazole-7-carboxamide (CID 167502208) is N-(8-fluoro-2-methylimidazo[1,2-a]pyridin-6-yl)-2-methyl-4-[(3R)-3-propan-2-ylpiperazin-1-yl]indazole-7-carboxamide.
What is the SMILES notation for N-(8-fluoro-2-methylimidazo[1,2-a]pyridin-6-yl)-2-methyl-4-[(3R)-3-propan-2-ylpiperazin-1-yl]indazole-7-carboxamide?
The canonical SMILES for N-(8-fluoro-2-methylimidazo[1,2-a]pyridin-6-yl)-2-methyl-4-[(3R)-3-propan-2-ylpiperazin-1-yl]indazole-7-carboxamide is Cc1cn2cc(NC(=O)c3ccc(N4CCN[C@H](C(C)C)C4)c4cn(C)nc34)cc(F)c2n1.
What is the InChIKey of N-(8-fluoro-2-methylimidazo[1,2-a]pyridin-6-yl)-2-methyl-4-[(3R)-3-propan-2-ylpiperazin-1-yl]indazole-7-carboxamide?
The InChIKey is HIZPPRSXDDHYDZ-FQEVSTJZSA-N. The full InChI is InChI=1S/C24H28FN7O/c1-14(2)20-13-31(8-7-26-20)21-6-5-17(22-18(21)12-30(4)29-22)24(33)28-16-9-19(25)23-27-15(3)10-32(23)11-16/h5-6,9-12,14,20,26H,7-8,13H2,1-4H3,(H,28,33)/t20-/m0/s1.
What are the key properties of N-(8-fluoro-2-methylimidazo[1,2-a]pyridin-6-yl)-2-methyl-4-[(3R)-3-propan-2-ylpiperazin-1-yl]indazole-7-carboxamide?
N-(8-fluoro-2-methylimidazo[1,2-a]pyridin-6-yl)-2-methyl-4-[(3R)-3-propan-2-ylpiperazin-1-yl]indazole-7-carboxamide has a molecular weight of 449.53 g/mol, XLogP of 3.36, 4 rotatable bonds, 2 hydrogen bond donors, and 7 hydrogen bond acceptors.
Where does this data come from?
All data for N-(8-fluoro-2-methylimidazo[1,2-a]pyridin-6-yl)-2-methyl-4-[(3R)-3-propan-2-ylpiperazin-1-yl]indazole-7-carboxamide is sourced from PubChem (CID 167502208), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).