N-[4-[2-[[5-tert-butyl-1-[(3R)-oxolan-3-yl]pyrazol-3-yl]amino]-7-methoxy-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-[(3S)-oxolan-3-yl]pyrazol-3-yl]amino]-7-methoxy-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-(oxolan-3-yl)pyrazol-3-yl]amino]-7-methoxy-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[7-chloro-2-[[5-(2-cyanopropan-2-yl)-1-(oxolan-3-yl)pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[7-chloro-2-[[5-(2-cyanopropan-2-yl)-1-[(3R)-oxolan-3-yl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[7-chloro-2-[[1-(3-methoxycyclobutyl)-5-(1,1,2,2,2-pentafluoroethyl)pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-(2-cyanopropan-2-yl)-1-[(3R)-oxolan-3-yl]pyrazol-3-yl]amino]-7-ethyl-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[7-(difluoromethyl)-2-[[5-(2-isocyanopropan-2-yl)-1-(oxolan-3-yl)pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[7-(difluoromethyl)-2-[[5-(2-isocyanopropan-2-yl)-1-[(3R)-oxolan-3-yl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[7-ethyl-2-[[5-(2-isocyanopropan-2-yl)-1-[(3S)-oxolan-3-yl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide

C258H286Cl3F9N86O33 — CID 167533318

IUPACN-[4-[2-[[5-tert-butyl-1-[(3R)-oxolan-3-yl]pyrazol-3-yl]amino]-7-methoxy-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-[(3S)-oxolan-3-yl]pyrazol-3-yl]amino]-7-methoxy-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-(oxolan-3-yl)pyrazol-3-yl]amino]-7-methoxy-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[7-chloro-2-[[5-(2-cyanopropan-2-yl)-1-(oxolan-3-yl)pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[7-chloro-2-[[5-(2-cyanopropan-2-yl)-1-[(3R)-oxolan-3-yl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[7-chloro-2-[[1-(3-methoxycyclobutyl)-5-(1,1,2,2,2-pentafluoroethyl)pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-(2-cyanopropan-2-yl)-1-[(3R)-oxolan-3-yl]pyrazol-3-yl]amino]-7-ethyl-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[7-(difluoromethyl)-2-[[5-(2-isocyanopropan-2-yl)-1-(oxolan-3-yl)pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[7-(difluoromethyl)-2-[[5-(2-isocyanopropan-2-yl)-1-[(3R)-oxolan-3-yl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[7-ethyl-2-[[5-(2-isocyanopropan-2-yl)-1-[(3S)-oxolan-3-yl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide
SMILESCC(=O)Nc1cc(Oc2cnc3nc(Nc4cc(C(C)(C)C#N)n(C5CCOC5)n4)n(C)c3c2Cl)ccn1.CC(=O)Nc1cc(Oc2cnc3nc(Nc4cc(C(C)(C)C#N)n([C@@H]5CCOC5)n4)n(C)c3c2Cl)ccn1.CCc1c(Oc2ccnc(NC(C)=O)c2)cnc2nc(Nc3cc(C(C)(C)C#N)n([C@@H]4CCOC4)n3)n(C)c12.COC1CC(n2nc(Nc3nc4ncc(Oc5ccnc(NC(C)=O)c5)c(Cl)c4n3C)cc2C(F)(F)C(F)(F)F)C1.COc1c(Oc2ccnc(NC(C)=O)c2)cnc2nc(Nc3cc(C(C)(C)C)n(C4CCOC4)n3)n(C)c12.COc1c(Oc2ccnc(NC(C)=O)c2)cnc2nc(Nc3cc(C(C)(C)C)n([C@@H]4CCOC4)n3)n(C)c12.COc1c(Oc2ccnc(NC(C)=O)c2)cnc2nc(Nc3cc(C(C)(C)C)n([C@H]4CCOC4)n3)n(C)c12.[C-]#[N+]C(C)(C)c1cc(Nc2nc3ncc(Oc4ccnc(NC(C)=O)c4)c(C(F)F)c3n2C)nn1C1CCOC1.[C-]#[N+]C(C)(C)c1cc(Nc2nc3ncc(Oc4ccnc(NC(C)=O)c4)c(C(F)F)c3n2C)nn1[C@@H]1CCOC1.[C-]#[N+]C(C)(C)c1cc(Nc2nc3ncc(Oc4ccnc(NC(C)=O)c4)c(CC)c3n2C)nn1[C@H]1CCOC1
InChIInChI=1S/2C27H31N9O3.2C26H27F2N9O3.3C26H32N8O4.2C25H26ClN9O3.C24H22ClF5N8O3/c1-7-19-20(39-18-8-10-29-22(12-18)31-16(2)37)14-30-25-24(19)35(6)26(33-25)32-23-13-21(27(3,4)28-5)36(34-23)17-9-11-38-15-17;1-6-19-20(39-18-7-9-29-22(11-18)31-16(2)37)13-30-25-24(19)35(5)26(33-25)32-23-12-21(27(3,4)15-28)36(34-23)17-8-10-38-14-17;2*1-14(38)32-19-10-16(6-8-30-19)40-17-12-31-24-22(21(17)23(27)28)36(5)25(34-24)33-20-11-18(26(2,3)29-4)37(35-20)15-7-9-39-13-15;3*1-15(35)29-20-11-17(7-9-27-20)38-18-13-28-24-22(23(18)36-6)33(5)25(31-24)30-21-12-19(26(2,3)4)34(32-21)16-8-10-37-14-16;2*1-14(36)30-19-9-16(5-7-28-19)38-17-11-29-23-22(21(17)26)34(4)24(32-23)31-20-10-18(25(2,3)13-27)35(33-20)15-6-8-37-12-15;1-11(39)33-17-8-13(4-5-31-17)41-15-10-32-21-20(19(15)25)37(2)22(35-21)34-18-9-16(23(26,27)24(28,29)30)38(36-18)12-6-14(7-12)40-3/h8,10,12-14,17H,7,9,11,15H2,1-4,6H3,(H,29,31,37)(H,30,32,33,34);7,9,11-13,17H,6,8,10,14H2,1-5H3,(H,29,31,37)(H,30,32,33,34);2*6,8,10-12,15,23H,7,9,13H2,1-3,5H3,(H,30,32,38)(H,31,33,34,35);3*7,9,11-13,16H,8,10,14H2,1-6H3,(H,27,29,35)(H,28,30,31,32);2*5,7,9-11,15H,6,8,12H2,1-4H3,(H,28,30,36)(H,29,31,32,33);4-5,8-10,12,14H,6-7H2,1-3H3,(H,31,33,39)(H,32,34,35,36)/t2*17-;15-;;2*16-;;15-;;/m011.10.1../s1
InChIKeyAGJSYGFQSLWBQC-CFLHOQETSA-N
MW5397.04 g/mol
LogP46.94
Rot. Bonds75

About N-[4-[2-[[5-tert-butyl-1-[(3R)-oxolan-3-yl]pyrazol-3-yl]amino]-7-methoxy-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-[(3S)-oxolan-3-yl]pyrazol-3-yl]amino]-7-methoxy-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-(oxolan-3-yl)pyrazol-3-yl]amino]-7-methoxy-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[7-chloro-2-[[5-(2-cyanopropan-2-yl)-1-(oxolan-3-yl)pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[7-chloro-2-[[5-(2-cyanopropan-2-yl)-1-[(3R)-oxolan-3-yl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[7-chloro-2-[[1-(3-methoxycyclobutyl)-5-(1,1,2,2,2-pentafluoroethyl)pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-(2-cyanopropan-2-yl)-1-[(3R)-oxolan-3-yl]pyrazol-3-yl]amino]-7-ethyl-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[7-(difluoromethyl)-2-[[5-(2-isocyanopropan-2-yl)-1-(oxolan-3-yl)pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[7-(difluoromethyl)-2-[[5-(2-isocyanopropan-2-yl)-1-[(3R)-oxolan-3-yl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[7-ethyl-2-[[5-(2-isocyanopropan-2-yl)-1-[(3S)-oxolan-3-yl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide

N-[4-[2-[[5-tert-butyl-1-[(3R)-oxolan-3-yl]pyrazol-3-yl]amino]-7-methoxy-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-[(3S)-oxolan-3-yl]pyrazol-3-yl]amino]-7-methoxy-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-(oxolan-3-yl)pyrazol-3-yl]amino]-7-methoxy-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[7-chloro-2-[[5-(2-cyanopropan-2-yl)-1-(oxolan-3-yl)pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[7-chloro-2-[[5-(2-cyanopropan-2-yl)-1-[(3R)-oxolan-3-yl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[7-chloro-2-[[1-(3-methoxycyclobutyl)-5-(1,1,2,2,2-pentafluoroethyl)pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-(2-cyanopropan-2-yl)-1-[(3R)-oxolan-3-yl]pyrazol-3-yl]amino]-7-ethyl-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[7-(difluoromethyl)-2-[[5-(2-isocyanopropan-2-yl)-1-(oxolan-3-yl)pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[7-(difluoromethyl)-2-[[5-(2-isocyanopropan-2-yl)-1-[(3R)-oxolan-3-yl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[7-ethyl-2-[[5-(2-isocyanopropan-2-yl)-1-[(3S)-oxolan-3-yl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide (PubChem CID 167533318) has the molecular formula C258H286Cl3F9N86O33 and a molecular weight of 5397.04 g/mol. Its IUPAC name is N-[4-[2-[[5-tert-butyl-1-[(3R)-oxolan-3-yl]pyrazol-3-yl]amino]-7-methoxy-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-[(3S)-oxolan-3-yl]pyrazol-3-yl]amino]-7-methoxy-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-(oxolan-3-yl)pyrazol-3-yl]amino]-7-methoxy-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[7-chloro-2-[[5-(2-cyanopropan-2-yl)-1-(oxolan-3-yl)pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[7-chloro-2-[[5-(2-cyanopropan-2-yl)-1-[(3R)-oxolan-3-yl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[7-chloro-2-[[1-(3-methoxycyclobutyl)-5-(1,1,2,2,2-pentafluoroethyl)pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-(2-cyanopropan-2-yl)-1-[(3R)-oxolan-3-yl]pyrazol-3-yl]amino]-7-ethyl-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[7-(difluoromethyl)-2-[[5-(2-isocyanopropan-2-yl)-1-(oxolan-3-yl)pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[7-(difluoromethyl)-2-[[5-(2-isocyanopropan-2-yl)-1-[(3R)-oxolan-3-yl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[7-ethyl-2-[[5-(2-isocyanopropan-2-yl)-1-[(3S)-oxolan-3-yl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide.

Molecular Properties

Compound NameN-[4-[2-[[5-tert-butyl-1-[(3R)-oxolan-3-yl]pyrazol-3-yl]amino]-7-methoxy-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-[(3S)-oxolan-3-yl]pyrazol-3-yl]amino]-7-methoxy-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-(oxolan-3-yl)pyrazol-3-yl]amino]-7-methoxy-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[7-chloro-2-[[5-(2-cyanopropan-2-yl)-1-(oxolan-3-yl)pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[7-chloro-2-[[5-(2-cyanopropan-2-yl)-1-[(3R)-oxolan-3-yl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[7-chloro-2-[[1-(3-methoxycyclobutyl)-5-(1,1,2,2,2-pentafluoroethyl)pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-(2-cyanopropan-2-yl)-1-[(3R)-oxolan-3-yl]pyrazol-3-yl]amino]-7-ethyl-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[7-(difluoromethyl)-2-[[5-(2-isocyanopropan-2-yl)-1-(oxolan-3-yl)pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[7-(difluoromethyl)-2-[[5-(2-isocyanopropan-2-yl)-1-[(3R)-oxolan-3-yl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[7-ethyl-2-[[5-(2-isocyanopropan-2-yl)-1-[(3S)-oxolan-3-yl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide
PubChem CID167533318
Molecular FormulaC258H286Cl3F9N86O33
Molecular Weight5397.04 g/mol
Exact Mass5392.23
IUPAC NameN-[4-[2-[[5-tert-butyl-1-[(3R)-oxolan-3-yl]pyrazol-3-yl]amino]-7-methoxy-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-[(3S)-oxolan-3-yl]pyrazol-3-yl]amino]-7-methoxy-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-(oxolan-3-yl)pyrazol-3-yl]amino]-7-methoxy-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[7-chloro-2-[[5-(2-cyanopropan-2-yl)-1-(oxolan-3-yl)pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[7-chloro-2-[[5-(2-cyanopropan-2-yl)-1-[(3R)-oxolan-3-yl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[7-chloro-2-[[1-(3-methoxycyclobutyl)-5-(1,1,2,2,2-pentafluoroethyl)pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-(2-cyanopropan-2-yl)-1-[(3R)-oxolan-3-yl]pyrazol-3-yl]amino]-7-ethyl-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[7-(difluoromethyl)-2-[[5-(2-isocyanopropan-2-yl)-1-(oxolan-3-yl)pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[7-(difluoromethyl)-2-[[5-(2-isocyanopropan-2-yl)-1-[(3R)-oxolan-3-yl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[7-ethyl-2-[[5-(2-isocyanopropan-2-yl)-1-[(3S)-oxolan-3-yl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide
SMILESCC(=O)Nc1cc(Oc2cnc3nc(Nc4cc(C(C)(C)C#N)n(C5CCOC5)n4)n(C)c3c2Cl)ccn1.CC(=O)Nc1cc(Oc2cnc3nc(Nc4cc(C(C)(C)C#N)n([C@@H]5CCOC5)n4)n(C)c3c2Cl)ccn1.CCc1c(Oc2ccnc(NC(C)=O)c2)cnc2nc(Nc3cc(C(C)(C)C#N)n([C@@H]4CCOC4)n3)n(C)c12.COC1CC(n2nc(Nc3nc4ncc(Oc5ccnc(NC(C)=O)c5)c(Cl)c4n3C)cc2C(F)(F)C(F)(F)F)C1.COc1c(Oc2ccnc(NC(C)=O)c2)cnc2nc(Nc3cc(C(C)(C)C)n(C4CCOC4)n3)n(C)c12.COc1c(Oc2ccnc(NC(C)=O)c2)cnc2nc(Nc3cc(C(C)(C)C)n([C@@H]4CCOC4)n3)n(C)c12.COc1c(Oc2ccnc(NC(C)=O)c2)cnc2nc(Nc3cc(C(C)(C)C)n([C@H]4CCOC4)n3)n(C)c12.[C-]#[N+]C(C)(C)c1cc(Nc2nc3ncc(Oc4ccnc(NC(C)=O)c4)c(C(F)F)c3n2C)nn1C1CCOC1.[C-]#[N+]C(C)(C)c1cc(Nc2nc3ncc(Oc4ccnc(NC(C)=O)c4)c(C(F)F)c3n2C)nn1[C@@H]1CCOC1.[C-]#[N+]C(C)(C)c1cc(Nc2nc3ncc(Oc4ccnc(NC(C)=O)c4)c(CC)c3n2C)nn1[C@H]1CCOC1
InChIInChI=1S/2C27H31N9O3.2C26H27F2N9O3.3C26H32N8O4.2C25H26ClN9O3.C24H22ClF5N8O3/c1-7-19-20(39-18-8-10-29-22(12-18)31-16(2)37)14-30-25-24(19)35(6)26(33-25)32-23-13-21(27(3,4)28-5)36(34-23)17-9-11-38-15-17;1-6-19-20(39-18-7-9-29-22(11-18)31-16(2)37)13-30-25-24(19)35(5)26(33-25)32-23-12-21(27(3,4)15-28)36(34-23)17-8-10-38-14-17;2*1-14(38)32-19-10-16(6-8-30-19)40-17-12-31-24-22(21(17)23(27)28)36(5)25(34-24)33-20-11-18(26(2,3)29-4)37(35-20)15-7-9-39-13-15;3*1-15(35)29-20-11-17(7-9-27-20)38-18-13-28-24-22(23(18)36-6)33(5)25(31-24)30-21-12-19(26(2,3)4)34(32-21)16-8-10-37-14-16;2*1-14(36)30-19-9-16(5-7-28-19)38-17-11-29-23-22(21(17)26)34(4)24(32-23)31-20-10-18(25(2,3)13-27)35(33-20)15-6-8-37-12-15;1-11(39)33-17-8-13(4-5-31-17)41-15-10-32-21-20(19(15)25)37(2)22(35-21)34-18-9-16(23(26,27)24(28,29)30)38(36-18)12-6-14(7-12)40-3/h8,10,12-14,17H,7,9,11,15H2,1-4,6H3,(H,29,31,37)(H,30,32,33,34);7,9,11-13,17H,6,8,10,14H2,1-5H3,(H,29,31,37)(H,30,32,33,34);2*6,8,10-12,15,23H,7,9,13H2,1-3,5H3,(H,30,32,38)(H,31,33,34,35);3*7,9,11-13,16H,8,10,14H2,1-6H3,(H,27,29,35)(H,28,30,31,32);2*5,7,9-11,15H,6,8,12H2,1-4H3,(H,28,30,36)(H,29,31,32,33);4-5,8-10,12,14H,6-7H2,1-3H3,(H,31,33,39)(H,32,34,35,36)/t2*17-;15-;;2*16-;;15-;;/m011.10.1../s1
InChIKeyAGJSYGFQSLWBQC-CFLHOQETSA-N
XLogP46.94
TPSA1322.24 Ų
H-Bond Donors20
H-Bond Acceptors106
Rotatable Bonds75
Heavy Atoms389
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5005397.04
LogP ≤ 546.94
H-Bond Donors ≤ 520
H-Bond Acceptors ≤ 10106

Analyze N-[4-[2-[[5-tert-butyl-1-[(3R)-oxolan-3-yl]pyrazol-3-yl]amino]-7-methoxy-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-[(3S)-oxolan-3-yl]pyrazol-3-yl]amino]-7-methoxy-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-(oxolan-3-yl)pyrazol-3-yl]amino]-7-methoxy-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[7-chloro-2-[[5-(2-cyanopropan-2-yl)-1-(oxolan-3-yl)pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[7-chloro-2-[[5-(2-cyanopropan-2-yl)-1-[(3R)-oxolan-3-yl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[7-chloro-2-[[1-(3-methoxycyclobutyl)-5-(1,1,2,2,2-pentafluoroethyl)pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-(2-cyanopropan-2-yl)-1-[(3R)-oxolan-3-yl]pyrazol-3-yl]amino]-7-ethyl-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[7-(difluoromethyl)-2-[[5-(2-isocyanopropan-2-yl)-1-(oxolan-3-yl)pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[7-(difluoromethyl)-2-[[5-(2-isocyanopropan-2-yl)-1-[(3R)-oxolan-3-yl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[7-ethyl-2-[[5-(2-isocyanopropan-2-yl)-1-[(3S)-oxolan-3-yl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide with MolForge

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Frequently Asked Questions

What is the IUPAC name of N-[4-[2-[[5-tert-butyl-1-[(3R)-oxolan-3-yl]pyrazol-3-yl]amino]-7-methoxy-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-[(3S)-oxolan-3-yl]pyrazol-3-yl]amino]-7-methoxy-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-(oxolan-3-yl)pyrazol-3-yl]amino]-7-methoxy-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[7-chloro-2-[[5-(2-cyanopropan-2-yl)-1-(oxolan-3-yl)pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[7-chloro-2-[[5-(2-cyanopropan-2-yl)-1-[(3R)-oxolan-3-yl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[7-chloro-2-[[1-(3-methoxycyclobutyl)-5-(1,1,2,2,2-pentafluoroethyl)pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-(2-cyanopropan-2-yl)-1-[(3R)-oxolan-3-yl]pyrazol-3-yl]amino]-7-ethyl-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[7-(difluoromethyl)-2-[[5-(2-isocyanopropan-2-yl)-1-(oxolan-3-yl)pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[7-(difluoromethyl)-2-[[5-(2-isocyanopropan-2-yl)-1-[(3R)-oxolan-3-yl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[7-ethyl-2-[[5-(2-isocyanopropan-2-yl)-1-[(3S)-oxolan-3-yl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide?
The IUPAC name of N-[4-[2-[[5-tert-butyl-1-[(3R)-oxolan-3-yl]pyrazol-3-yl]amino]-7-methoxy-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-[(3S)-oxolan-3-yl]pyrazol-3-yl]amino]-7-methoxy-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-(oxolan-3-yl)pyrazol-3-yl]amino]-7-methoxy-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[7-chloro-2-[[5-(2-cyanopropan-2-yl)-1-(oxolan-3-yl)pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[7-chloro-2-[[5-(2-cyanopropan-2-yl)-1-[(3R)-oxolan-3-yl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[7-chloro-2-[[1-(3-methoxycyclobutyl)-5-(1,1,2,2,2-pentafluoroethyl)pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-(2-cyanopropan-2-yl)-1-[(3R)-oxolan-3-yl]pyrazol-3-yl]amino]-7-ethyl-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[7-(difluoromethyl)-2-[[5-(2-isocyanopropan-2-yl)-1-(oxolan-3-yl)pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[7-(difluoromethyl)-2-[[5-(2-isocyanopropan-2-yl)-1-[(3R)-oxolan-3-yl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[7-ethyl-2-[[5-(2-isocyanopropan-2-yl)-1-[(3S)-oxolan-3-yl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide (CID 167533318) is N-[4-[2-[[5-tert-butyl-1-[(3R)-oxolan-3-yl]pyrazol-3-yl]amino]-7-methoxy-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-[(3S)-oxolan-3-yl]pyrazol-3-yl]amino]-7-methoxy-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-(oxolan-3-yl)pyrazol-3-yl]amino]-7-methoxy-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[7-chloro-2-[[5-(2-cyanopropan-2-yl)-1-(oxolan-3-yl)pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[7-chloro-2-[[5-(2-cyanopropan-2-yl)-1-[(3R)-oxolan-3-yl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[7-chloro-2-[[1-(3-methoxycyclobutyl)-5-(1,1,2,2,2-pentafluoroethyl)pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-(2-cyanopropan-2-yl)-1-[(3R)-oxolan-3-yl]pyrazol-3-yl]amino]-7-ethyl-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[7-(difluoromethyl)-2-[[5-(2-isocyanopropan-2-yl)-1-(oxolan-3-yl)pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[7-(difluoromethyl)-2-[[5-(2-isocyanopropan-2-yl)-1-[(3R)-oxolan-3-yl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[7-ethyl-2-[[5-(2-isocyanopropan-2-yl)-1-[(3S)-oxolan-3-yl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide.
What is the SMILES notation for N-[4-[2-[[5-tert-butyl-1-[(3R)-oxolan-3-yl]pyrazol-3-yl]amino]-7-methoxy-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-[(3S)-oxolan-3-yl]pyrazol-3-yl]amino]-7-methoxy-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-(oxolan-3-yl)pyrazol-3-yl]amino]-7-methoxy-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[7-chloro-2-[[5-(2-cyanopropan-2-yl)-1-(oxolan-3-yl)pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[7-chloro-2-[[5-(2-cyanopropan-2-yl)-1-[(3R)-oxolan-3-yl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[7-chloro-2-[[1-(3-methoxycyclobutyl)-5-(1,1,2,2,2-pentafluoroethyl)pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-(2-cyanopropan-2-yl)-1-[(3R)-oxolan-3-yl]pyrazol-3-yl]amino]-7-ethyl-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[7-(difluoromethyl)-2-[[5-(2-isocyanopropan-2-yl)-1-(oxolan-3-yl)pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[7-(difluoromethyl)-2-[[5-(2-isocyanopropan-2-yl)-1-[(3R)-oxolan-3-yl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[7-ethyl-2-[[5-(2-isocyanopropan-2-yl)-1-[(3S)-oxolan-3-yl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide?
The canonical SMILES for N-[4-[2-[[5-tert-butyl-1-[(3R)-oxolan-3-yl]pyrazol-3-yl]amino]-7-methoxy-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-[(3S)-oxolan-3-yl]pyrazol-3-yl]amino]-7-methoxy-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-(oxolan-3-yl)pyrazol-3-yl]amino]-7-methoxy-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[7-chloro-2-[[5-(2-cyanopropan-2-yl)-1-(oxolan-3-yl)pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[7-chloro-2-[[5-(2-cyanopropan-2-yl)-1-[(3R)-oxolan-3-yl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[7-chloro-2-[[1-(3-methoxycyclobutyl)-5-(1,1,2,2,2-pentafluoroethyl)pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-(2-cyanopropan-2-yl)-1-[(3R)-oxolan-3-yl]pyrazol-3-yl]amino]-7-ethyl-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[7-(difluoromethyl)-2-[[5-(2-isocyanopropan-2-yl)-1-(oxolan-3-yl)pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[7-(difluoromethyl)-2-[[5-(2-isocyanopropan-2-yl)-1-[(3R)-oxolan-3-yl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[7-ethyl-2-[[5-(2-isocyanopropan-2-yl)-1-[(3S)-oxolan-3-yl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide is CC(=O)Nc1cc(Oc2cnc3nc(Nc4cc(C(C)(C)C#N)n(C5CCOC5)n4)n(C)c3c2Cl)ccn1.CC(=O)Nc1cc(Oc2cnc3nc(Nc4cc(C(C)(C)C#N)n([C@@H]5CCOC5)n4)n(C)c3c2Cl)ccn1.CCc1c(Oc2ccnc(NC(C)=O)c2)cnc2nc(Nc3cc(C(C)(C)C#N)n([C@@H]4CCOC4)n3)n(C)c12.COC1CC(n2nc(Nc3nc4ncc(Oc5ccnc(NC(C)=O)c5)c(Cl)c4n3C)cc2C(F)(F)C(F)(F)F)C1.COc1c(Oc2ccnc(NC(C)=O)c2)cnc2nc(Nc3cc(C(C)(C)C)n(C4CCOC4)n3)n(C)c12.COc1c(Oc2ccnc(NC(C)=O)c2)cnc2nc(Nc3cc(C(C)(C)C)n([C@@H]4CCOC4)n3)n(C)c12.COc1c(Oc2ccnc(NC(C)=O)c2)cnc2nc(Nc3cc(C(C)(C)C)n([C@H]4CCOC4)n3)n(C)c12.[C-]#[N+]C(C)(C)c1cc(Nc2nc3ncc(Oc4ccnc(NC(C)=O)c4)c(C(F)F)c3n2C)nn1C1CCOC1.[C-]#[N+]C(C)(C)c1cc(Nc2nc3ncc(Oc4ccnc(NC(C)=O)c4)c(C(F)F)c3n2C)nn1[C@@H]1CCOC1.[C-]#[N+]C(C)(C)c1cc(Nc2nc3ncc(Oc4ccnc(NC(C)=O)c4)c(CC)c3n2C)nn1[C@H]1CCOC1.
What is the InChIKey of N-[4-[2-[[5-tert-butyl-1-[(3R)-oxolan-3-yl]pyrazol-3-yl]amino]-7-methoxy-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-[(3S)-oxolan-3-yl]pyrazol-3-yl]amino]-7-methoxy-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-(oxolan-3-yl)pyrazol-3-yl]amino]-7-methoxy-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[7-chloro-2-[[5-(2-cyanopropan-2-yl)-1-(oxolan-3-yl)pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[7-chloro-2-[[5-(2-cyanopropan-2-yl)-1-[(3R)-oxolan-3-yl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[7-chloro-2-[[1-(3-methoxycyclobutyl)-5-(1,1,2,2,2-pentafluoroethyl)pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-(2-cyanopropan-2-yl)-1-[(3R)-oxolan-3-yl]pyrazol-3-yl]amino]-7-ethyl-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[7-(difluoromethyl)-2-[[5-(2-isocyanopropan-2-yl)-1-(oxolan-3-yl)pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[7-(difluoromethyl)-2-[[5-(2-isocyanopropan-2-yl)-1-[(3R)-oxolan-3-yl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[7-ethyl-2-[[5-(2-isocyanopropan-2-yl)-1-[(3S)-oxolan-3-yl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide?
The InChIKey is AGJSYGFQSLWBQC-CFLHOQETSA-N. The full InChI is InChI=1S/2C27H31N9O3.2C26H27F2N9O3.3C26H32N8O4.2C25H26ClN9O3.C24H22ClF5N8O3/c1-7-19-20(39-18-8-10-29-22(12-18)31-16(2)37)14-30-25-24(19)35(6)26(33-25)32-23-13-21(27(3,4)28-5)36(34-23)17-9-11-38-15-17;1-6-19-20(39-18-7-9-29-22(11-18)31-16(2)37)13-30-25-24(19)35(5)26(33-25)32-23-12-21(27(3,4)15-28)36(34-23)17-8-10-38-14-17;2*1-14(38)32-19-10-16(6-8-30-19)40-17-12-31-24-22(21(17)23(27)28)36(5)25(34-24)33-20-11-18(26(2,3)29-4)37(35-20)15-7-9-39-13-15;3*1-15(35)29-20-11-17(7-9-27-20)38-18-13-28-24-22(23(18)36-6)33(5)25(31-24)30-21-12-19(26(2,3)4)34(32-21)16-8-10-37-14-16;2*1-14(36)30-19-9-16(5-7-28-19)38-17-11-29-23-22(21(17)26)34(4)24(32-23)31-20-10-18(25(2,3)13-27)35(33-20)15-6-8-37-12-15;1-11(39)33-17-8-13(4-5-31-17)41-15-10-32-21-20(19(15)25)37(2)22(35-21)34-18-9-16(23(26,27)24(28,29)30)38(36-18)12-6-14(7-12)40-3/h8,10,12-14,17H,7,9,11,15H2,1-4,6H3,(H,29,31,37)(H,30,32,33,34);7,9,11-13,17H,6,8,10,14H2,1-5H3,(H,29,31,37)(H,30,32,33,34);2*6,8,10-12,15,23H,7,9,13H2,1-3,5H3,(H,30,32,38)(H,31,33,34,35);3*7,9,11-13,16H,8,10,14H2,1-6H3,(H,27,29,35)(H,28,30,31,32);2*5,7,9-11,15H,6,8,12H2,1-4H3,(H,28,30,36)(H,29,31,32,33);4-5,8-10,12,14H,6-7H2,1-3H3,(H,31,33,39)(H,32,34,35,36)/t2*17-;15-;;2*16-;;15-;;/m011.10.1../s1.
What are the key properties of N-[4-[2-[[5-tert-butyl-1-[(3R)-oxolan-3-yl]pyrazol-3-yl]amino]-7-methoxy-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-[(3S)-oxolan-3-yl]pyrazol-3-yl]amino]-7-methoxy-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-(oxolan-3-yl)pyrazol-3-yl]amino]-7-methoxy-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[7-chloro-2-[[5-(2-cyanopropan-2-yl)-1-(oxolan-3-yl)pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[7-chloro-2-[[5-(2-cyanopropan-2-yl)-1-[(3R)-oxolan-3-yl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[7-chloro-2-[[1-(3-methoxycyclobutyl)-5-(1,1,2,2,2-pentafluoroethyl)pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-(2-cyanopropan-2-yl)-1-[(3R)-oxolan-3-yl]pyrazol-3-yl]amino]-7-ethyl-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[7-(difluoromethyl)-2-[[5-(2-isocyanopropan-2-yl)-1-(oxolan-3-yl)pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[7-(difluoromethyl)-2-[[5-(2-isocyanopropan-2-yl)-1-[(3R)-oxolan-3-yl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[7-ethyl-2-[[5-(2-isocyanopropan-2-yl)-1-[(3S)-oxolan-3-yl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide?
N-[4-[2-[[5-tert-butyl-1-[(3R)-oxolan-3-yl]pyrazol-3-yl]amino]-7-methoxy-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-[(3S)-oxolan-3-yl]pyrazol-3-yl]amino]-7-methoxy-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-(oxolan-3-yl)pyrazol-3-yl]amino]-7-methoxy-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[7-chloro-2-[[5-(2-cyanopropan-2-yl)-1-(oxolan-3-yl)pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[7-chloro-2-[[5-(2-cyanopropan-2-yl)-1-[(3R)-oxolan-3-yl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[7-chloro-2-[[1-(3-methoxycyclobutyl)-5-(1,1,2,2,2-pentafluoroethyl)pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-(2-cyanopropan-2-yl)-1-[(3R)-oxolan-3-yl]pyrazol-3-yl]amino]-7-ethyl-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[7-(difluoromethyl)-2-[[5-(2-isocyanopropan-2-yl)-1-(oxolan-3-yl)pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[7-(difluoromethyl)-2-[[5-(2-isocyanopropan-2-yl)-1-[(3R)-oxolan-3-yl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[7-ethyl-2-[[5-(2-isocyanopropan-2-yl)-1-[(3S)-oxolan-3-yl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide has a molecular weight of 5397.04 g/mol, XLogP of 46.94, 75 rotatable bonds, 20 hydrogen bond donors, and 106 hydrogen bond acceptors.
Where does this data come from?
All data for N-[4-[2-[[5-tert-butyl-1-[(3R)-oxolan-3-yl]pyrazol-3-yl]amino]-7-methoxy-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-[(3S)-oxolan-3-yl]pyrazol-3-yl]amino]-7-methoxy-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-tert-butyl-1-(oxolan-3-yl)pyrazol-3-yl]amino]-7-methoxy-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[7-chloro-2-[[5-(2-cyanopropan-2-yl)-1-(oxolan-3-yl)pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[7-chloro-2-[[5-(2-cyanopropan-2-yl)-1-[(3R)-oxolan-3-yl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[7-chloro-2-[[1-(3-methoxycyclobutyl)-5-(1,1,2,2,2-pentafluoroethyl)pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[2-[[5-(2-cyanopropan-2-yl)-1-[(3R)-oxolan-3-yl]pyrazol-3-yl]amino]-7-ethyl-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[7-(difluoromethyl)-2-[[5-(2-isocyanopropan-2-yl)-1-(oxolan-3-yl)pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[7-(difluoromethyl)-2-[[5-(2-isocyanopropan-2-yl)-1-[(3R)-oxolan-3-yl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide;N-[4-[7-ethyl-2-[[5-(2-isocyanopropan-2-yl)-1-[(3S)-oxolan-3-yl]pyrazol-3-yl]amino]-1-methylimidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]acetamide is sourced from PubChem (CID 167533318), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).