N-[(6-chloro-3-pyridinyl)methyl]-3-(7-methoxyquinolin-4-yl)oxy-2-methylbenzamide;3-(7-chloroquinolin-4-yl)oxy-N-[(2,5-difluoro-4-pyridinyl)methyl]-2-methylbenzamide;3-(7-chloroquinolin-4-yl)oxy-N-[(2,6-difluoro-4-pyridinyl)methyl]-2-methylbenzamide;N-[(2,5-difluoro-4-pyridinyl)methyl]-2-methyl-3-(7-methylquinolin-4-yl)oxybenzamide;N-[(2,6-difluoro-4-pyridinyl)methyl]-2-methyl-3-(7-methylquinolin-4-yl)oxybenzamide;N-[(2,6-dimethyl-4-pyridinyl)methyl]-3-(7-methoxyquinolin-4-yl)oxy-2-methylbenzamide;2-methyl-3-(7-methylquinolin-4-yl)oxy-N-[(2,3,6-trifluoro-4-pyridinyl)methyl]benzamide

C168H133Cl3F11N21O16 — CID 167548650

About N-[(6-chloro-3-pyridinyl)methyl]-3-(7-methoxyquinolin-4-yl)oxy-2-methylbenzamide;3-(7-chloroquinolin-4-yl)oxy-N-[(2,5-difluoro-4-pyridinyl)methyl]-2-methylbenzamide;3-(7-chloroquinolin-4-yl)oxy-N-[(2,6-difluoro-4-pyridinyl)methyl]-2-methylbenzamide;N-[(2,5-difluoro-4-pyridinyl)methyl]-2-methyl-3-(7-methylquinolin-4-yl)oxybenzamide;N-[(2,6-difluoro-4-pyridinyl)methyl]-2-methyl-3-(7-methylquinolin-4-yl)oxybenzamide;N-[(2,6-dimethyl-4-pyridinyl)methyl]-3-(7-methoxyquinolin-4-yl)oxy-2-methylbenzamide;2-methyl-3-(7-methylquinolin-4-yl)oxy-N-[(2,3,6-trifluoro-4-pyridinyl)methyl]benzamide

N-[(6-chloro-3-pyridinyl)methyl]-3-(7-methoxyquinolin-4-yl)oxy-2-methylbenzamide;3-(7-chloroquinolin-4-yl)oxy-N-[(2,5-difluoro-4-pyridinyl)methyl]-2-methylbenzamide;3-(7-chloroquinolin-4-yl)oxy-N-[(2,6-difluoro-4-pyridinyl)methyl]-2-methylbenzamide;N-[(2,5-difluoro-4-pyridinyl)methyl]-2-methyl-3-(7-methylquinolin-4-yl)oxybenzamide;N-[(2,6-difluoro-4-pyridinyl)methyl]-2-methyl-3-(7-methylquinolin-4-yl)oxybenzamide;N-[(2,6-dimethyl-4-pyridinyl)methyl]-3-(7-methoxyquinolin-4-yl)oxy-2-methylbenzamide;2-methyl-3-(7-methylquinolin-4-yl)oxy-N-[(2,3,6-trifluoro-4-pyridinyl)methyl]benzamide (PubChem CID 167548650) has the molecular formula C168H133Cl3F11N21O16 and a molecular weight of 3017.38 g/mol. Its IUPAC name is N-[(6-chloro-3-pyridinyl)methyl]-3-(7-methoxyquinolin-4-yl)oxy-2-methylbenzamide;3-(7-chloroquinolin-4-yl)oxy-N-[(2,5-difluoro-4-pyridinyl)methyl]-2-methylbenzamide;3-(7-chloroquinolin-4-yl)oxy-N-[(2,6-difluoro-4-pyridinyl)methyl]-2-methylbenzamide;N-[(2,5-difluoro-4-pyridinyl)methyl]-2-methyl-3-(7-methylquinolin-4-yl)oxybenzamide;N-[(2,6-difluoro-4-pyridinyl)methyl]-2-methyl-3-(7-methylquinolin-4-yl)oxybenzamide;N-[(2,6-dimethyl-4-pyridinyl)methyl]-3-(7-methoxyquinolin-4-yl)oxy-2-methylbenzamide;2-methyl-3-(7-methylquinolin-4-yl)oxy-N-[(2,3,6-trifluoro-4-pyridinyl)methyl]benzamide.

Molecular Properties

• Compound Name: N-[(6-chloro-3-pyridinyl)methyl]-3-(7-methoxyquinolin-4-yl)oxy-2-methylbenzamide;3-(7-chloroquinolin-4-yl)oxy-N-[(2,5-difluoro-4-pyridinyl)methyl]-2-methylbenzamide;3-(7-chloroquinolin-4-yl)oxy-N-[(2,6-difluoro-4-pyridinyl)methyl]-2-methylbenzamide;N-[(2,5-difluoro-4-pyridinyl)methyl]-2-methyl-3-(7-methylquinolin-4-yl)oxybenzamide;N-[(2,6-difluoro-4-pyridinyl)methyl]-2-methyl-3-(7-methylquinolin-4-yl)oxybenzamide;N-[(2,6-dimethyl-4-pyridinyl)methyl]-3-(7-methoxyquinolin-4-yl)oxy-2-methylbenzamide;2-methyl-3-(7-methylquinolin-4-yl)oxy-N-[(2,3,6-trifluoro-4-pyridinyl)methyl]benzamide
• PubChem CID: 167548650
• Molecular Formula: C168H133Cl3F11N21O16
• Molecular Weight: 3017.38 g/mol
• Exact Mass: 3013.91
• IUPAC Name: N-[(6-chloro-3-pyridinyl)methyl]-3-(7-methoxyquinolin-4-yl)oxy-2-methylbenzamide;3-(7-chloroquinolin-4-yl)oxy-N-[(2,5-difluoro-4-pyridinyl)methyl]-2-methylbenzamide;3-(7-chloroquinolin-4-yl)oxy-N-[(2,6-difluoro-4-pyridinyl)methyl]-2-methylbenzamide;N-[(2,5-difluoro-4-pyridinyl)methyl]-2-methyl-3-(7-methylquinolin-4-yl)oxybenzamide;N-[(2,6-difluoro-4-pyridinyl)methyl]-2-methyl-3-(7-methylquinolin-4-yl)oxybenzamide;N-[(2,6-dimethyl-4-pyridinyl)methyl]-3-(7-methoxyquinolin-4-yl)oxy-2-methylbenzamide;2-methyl-3-(7-methylquinolin-4-yl)oxy-N-[(2,3,6-trifluoro-4-pyridinyl)methyl]benzamide
• SMILES: COc1ccc2c(Oc3cccc(C(=O)NCc4cc(C)nc(C)c4)c3C)ccnc2c1.COc1ccc2c(Oc3cccc(C(=O)NCc4ccc(Cl)nc4)c3C)ccnc2c1.Cc1c(Oc2ccnc3cc(Cl)ccc23)cccc1C(=O)NCc1cc(F)nc(F)c1.Cc1c(Oc2ccnc3cc(Cl)ccc23)cccc1C(=O)NCc1cc(F)ncc1F.Cc1ccc2c(Oc3cccc(C(=O)NCc4cc(F)nc(F)c4)c3C)ccnc2c1.Cc1ccc2c(Oc3cccc(C(=O)NCc4cc(F)nc(F)c4F)c3C)ccnc2c1.Cc1ccc2c(Oc3cccc(C(=O)NCc4cc(F)ncc4F)c3C)ccnc2c1
• InChI: InChI=1S/C26H25N3O3.C24H20ClN3O3.C24H18F3N3O2.2C24H19F2N3O2.2C23H16ClF2N3O2/c1-16-12-19(13-17(2)29-16)15-28-26(30)21-6-5-7-24(18(21)3)32-25-10-11-27-23-14-20(31-4)8-9-22(23)25;1-15-18(24(29)28-14-16-6-9-23(25)27-13-16)4-3-5-21(15)31-22-10-11-26-20-12-17(30-2)7-8-19(20)22;1-13-6-7-17-18(10-13)28-9-8-20(17)32-19-5-3-4-16(14(19)2)24(31)29-12-15-11-21(25)30-23(27)22(15)26;1-14-6-7-18-20(10-14)27-9-8-22(18)31-21-5-3-4-17(15(21)2)24(30)29-12-16-11-23(26)28-13-19(16)25;1-14-6-7-18-19(10-14)27-9-8-21(18)31-20-5-3-4-17(15(20)2)24(30)28-13-16-11-22(25)29-23(26)12-16;1-13-16(23(30)29-11-14-9-22(26)28-12-18(14)25)3-2-4-20(13)31-21-7-8-27-19-10-15(24)5-6-17(19)21;1-13-16(23(30)28-12-14-9-21(25)29-22(26)10-14)3-2-4-19(13)31-20-7-8-27-18-11-15(24)5-6-17(18)20/h5-14H,15H2,1-4H3,(H,28,30);3-13H,14H2,1-2H3,(H,28,29);3-11H,12H2,1-2H3,(H,29,31);3-11,13H,12H2,1-2H3,(H,29,30);3-12H,13H2,1-2H3,(H,28,30);2-10,12H,11H2,1H3,(H,29,30);2-11H,12H2,1H3,(H,28,30)
• InChIKey: CCVUKMUFYVOHDS-UHFFFAOYSA-N
• XLogP: 37.67
• TPSA: 467.23 Ų
• H-Bond Donors: 7
• H-Bond Acceptors: 30
• Rotatable Bonds: 37
• Heavy Atoms: 219
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	3017.38
LogP ≤ 5	37.67
H-Bond Donors ≤ 5	7
H-Bond Acceptors ≤ 10	30

Computed Properties (RDKit)

• Structural Alerts: {'alert_name': '2-halo_pyridine', 'substructure': 'N/A'}

Frequently Asked Questions

What is the IUPAC name of N-[(6-chloro-3-pyridinyl)methyl]-3-(7-methoxyquinolin-4-yl)oxy-2-methylbenzamide;3-(7-chloroquinolin-4-yl)oxy-N-[(2,5-difluoro-4-pyridinyl)methyl]-2-methylbenzamide;3-(7-chloroquinolin-4-yl)oxy-N-[(2,6-difluoro-4-pyridinyl)methyl]-2-methylbenzamide;N-[(2,5-difluoro-4-pyridinyl)methyl]-2-methyl-3-(7-methylquinolin-4-yl)oxybenzamide;N-[(2,6-difluoro-4-pyridinyl)methyl]-2-methyl-3-(7-methylquinolin-4-yl)oxybenzamide;N-[(2,6-dimethyl-4-pyridinyl)methyl]-3-(7-methoxyquinolin-4-yl)oxy-2-methylbenzamide;2-methyl-3-(7-methylquinolin-4-yl)oxy-N-[(2,3,6-trifluoro-4-pyridinyl)methyl]benzamide?

The IUPAC name of N-[(6-chloro-3-pyridinyl)methyl]-3-(7-methoxyquinolin-4-yl)oxy-2-methylbenzamide;3-(7-chloroquinolin-4-yl)oxy-N-[(2,5-difluoro-4-pyridinyl)methyl]-2-methylbenzamide;3-(7-chloroquinolin-4-yl)oxy-N-[(2,6-difluoro-4-pyridinyl)methyl]-2-methylbenzamide;N-[(2,5-difluoro-4-pyridinyl)methyl]-2-methyl-3-(7-methylquinolin-4-yl)oxybenzamide;N-[(2,6-difluoro-4-pyridinyl)methyl]-2-methyl-3-(7-methylquinolin-4-yl)oxybenzamide;N-[(2,6-dimethyl-4-pyridinyl)methyl]-3-(7-methoxyquinolin-4-yl)oxy-2-methylbenzamide;2-methyl-3-(7-methylquinolin-4-yl)oxy-N-[(2,3,6-trifluoro-4-pyridinyl)methyl]benzamide (CID 167548650) is N-[(6-chloro-3-pyridinyl)methyl]-3-(7-methoxyquinolin-4-yl)oxy-2-methylbenzamide;3-(7-chloroquinolin-4-yl)oxy-N-[(2,5-difluoro-4-pyridinyl)methyl]-2-methylbenzamide;3-(7-chloroquinolin-4-yl)oxy-N-[(2,6-difluoro-4-pyridinyl)methyl]-2-methylbenzamide;N-[(2,5-difluoro-4-pyridinyl)methyl]-2-methyl-3-(7-methylquinolin-4-yl)oxybenzamide;N-[(2,6-difluoro-4-pyridinyl)methyl]-2-methyl-3-(7-methylquinolin-4-yl)oxybenzamide;N-[(2,6-dimethyl-4-pyridinyl)methyl]-3-(7-methoxyquinolin-4-yl)oxy-2-methylbenzamide;2-methyl-3-(7-methylquinolin-4-yl)oxy-N-[(2,3,6-trifluoro-4-pyridinyl)methyl]benzamide.

What is the SMILES notation for N-[(6-chloro-3-pyridinyl)methyl]-3-(7-methoxyquinolin-4-yl)oxy-2-methylbenzamide;3-(7-chloroquinolin-4-yl)oxy-N-[(2,5-difluoro-4-pyridinyl)methyl]-2-methylbenzamide;3-(7-chloroquinolin-4-yl)oxy-N-[(2,6-difluoro-4-pyridinyl)methyl]-2-methylbenzamide;N-[(2,5-difluoro-4-pyridinyl)methyl]-2-methyl-3-(7-methylquinolin-4-yl)oxybenzamide;N-[(2,6-difluoro-4-pyridinyl)methyl]-2-methyl-3-(7-methylquinolin-4-yl)oxybenzamide;N-[(2,6-dimethyl-4-pyridinyl)methyl]-3-(7-methoxyquinolin-4-yl)oxy-2-methylbenzamide;2-methyl-3-(7-methylquinolin-4-yl)oxy-N-[(2,3,6-trifluoro-4-pyridinyl)methyl]benzamide?

The canonical SMILES for N-[(6-chloro-3-pyridinyl)methyl]-3-(7-methoxyquinolin-4-yl)oxy-2-methylbenzamide;3-(7-chloroquinolin-4-yl)oxy-N-[(2,5-difluoro-4-pyridinyl)methyl]-2-methylbenzamide;3-(7-chloroquinolin-4-yl)oxy-N-[(2,6-difluoro-4-pyridinyl)methyl]-2-methylbenzamide;N-[(2,5-difluoro-4-pyridinyl)methyl]-2-methyl-3-(7-methylquinolin-4-yl)oxybenzamide;N-[(2,6-difluoro-4-pyridinyl)methyl]-2-methyl-3-(7-methylquinolin-4-yl)oxybenzamide;N-[(2,6-dimethyl-4-pyridinyl)methyl]-3-(7-methoxyquinolin-4-yl)oxy-2-methylbenzamide;2-methyl-3-(7-methylquinolin-4-yl)oxy-N-[(2,3,6-trifluoro-4-pyridinyl)methyl]benzamide is COc1ccc2c(Oc3cccc(C(=O)NCc4cc(C)nc(C)c4)c3C)ccnc2c1.COc1ccc2c(Oc3cccc(C(=O)NCc4ccc(Cl)nc4)c3C)ccnc2c1.Cc1c(Oc2ccnc3cc(Cl)ccc23)cccc1C(=O)NCc1cc(F)nc(F)c1.Cc1c(Oc2ccnc3cc(Cl)ccc23)cccc1C(=O)NCc1cc(F)ncc1F.Cc1ccc2c(Oc3cccc(C(=O)NCc4cc(F)nc(F)c4)c3C)ccnc2c1.Cc1ccc2c(Oc3cccc(C(=O)NCc4cc(F)nc(F)c4F)c3C)ccnc2c1.Cc1ccc2c(Oc3cccc(C(=O)NCc4cc(F)ncc4F)c3C)ccnc2c1.

What is the InChIKey of N-[(6-chloro-3-pyridinyl)methyl]-3-(7-methoxyquinolin-4-yl)oxy-2-methylbenzamide;3-(7-chloroquinolin-4-yl)oxy-N-[(2,5-difluoro-4-pyridinyl)methyl]-2-methylbenzamide;3-(7-chloroquinolin-4-yl)oxy-N-[(2,6-difluoro-4-pyridinyl)methyl]-2-methylbenzamide;N-[(2,5-difluoro-4-pyridinyl)methyl]-2-methyl-3-(7-methylquinolin-4-yl)oxybenzamide;N-[(2,6-difluoro-4-pyridinyl)methyl]-2-methyl-3-(7-methylquinolin-4-yl)oxybenzamide;N-[(2,6-dimethyl-4-pyridinyl)methyl]-3-(7-methoxyquinolin-4-yl)oxy-2-methylbenzamide;2-methyl-3-(7-methylquinolin-4-yl)oxy-N-[(2,3,6-trifluoro-4-pyridinyl)methyl]benzamide?

The InChIKey is CCVUKMUFYVOHDS-UHFFFAOYSA-N. The full InChI is InChI=1S/C26H25N3O3.C24H20ClN3O3.C24H18F3N3O2.2C24H19F2N3O2.2C23H16ClF2N3O2/c1-16-12-19(13-17(2)29-16)15-28-26(30)21-6-5-7-24(18(21)3)32-25-10-11-27-23-14-20(31-4)8-9-22(23)25;1-15-18(24(29)28-14-16-6-9-23(25)27-13-16)4-3-5-21(15)31-22-10-11-26-20-12-17(30-2)7-8-19(20)22;1-13-6-7-17-18(10-13)28-9-8-20(17)32-19-5-3-4-16(14(19)2)24(31)29-12-15-11-21(25)30-23(27)22(15)26;1-14-6-7-18-20(10-14)27-9-8-22(18)31-21-5-3-4-17(15(21)2)24(30)29-12-16-11-23(26)28-13-19(16)25;1-14-6-7-18-19(10-14)27-9-8-21(18)31-20-5-3-4-17(15(20)2)24(30)28-13-16-11-22(25)29-23(26)12-16;1-13-16(23(30)29-11-14-9-22(26)28-12-18(14)25)3-2-4-20(13)31-21-7-8-27-19-10-15(24)5-6-17(19)21;1-13-16(23(30)28-12-14-9-21(25)29-22(26)10-14)3-2-4-19(13)31-20-7-8-27-18-11-15(24)5-6-17(18)20/h5-14H,15H2,1-4H3,(H,28,30);3-13H,14H2,1-2H3,(H,28,29);3-11H,12H2,1-2H3,(H,29,31);3-11,13H,12H2,1-2H3,(H,29,30);3-12H,13H2,1-2H3,(H,28,30);2-10,12H,11H2,1H3,(H,29,30);2-11H,12H2,1H3,(H,28,30).

What are the key properties of N-[(6-chloro-3-pyridinyl)methyl]-3-(7-methoxyquinolin-4-yl)oxy-2-methylbenzamide;3-(7-chloroquinolin-4-yl)oxy-N-[(2,5-difluoro-4-pyridinyl)methyl]-2-methylbenzamide;3-(7-chloroquinolin-4-yl)oxy-N-[(2,6-difluoro-4-pyridinyl)methyl]-2-methylbenzamide;N-[(2,5-difluoro-4-pyridinyl)methyl]-2-methyl-3-(7-methylquinolin-4-yl)oxybenzamide;N-[(2,6-difluoro-4-pyridinyl)methyl]-2-methyl-3-(7-methylquinolin-4-yl)oxybenzamide;N-[(2,6-dimethyl-4-pyridinyl)methyl]-3-(7-methoxyquinolin-4-yl)oxy-2-methylbenzamide;2-methyl-3-(7-methylquinolin-4-yl)oxy-N-[(2,3,6-trifluoro-4-pyridinyl)methyl]benzamide?

N-[(6-chloro-3-pyridinyl)methyl]-3-(7-methoxyquinolin-4-yl)oxy-2-methylbenzamide;3-(7-chloroquinolin-4-yl)oxy-N-[(2,5-difluoro-4-pyridinyl)methyl]-2-methylbenzamide;3-(7-chloroquinolin-4-yl)oxy-N-[(2,6-difluoro-4-pyridinyl)methyl]-2-methylbenzamide;N-[(2,5-difluoro-4-pyridinyl)methyl]-2-methyl-3-(7-methylquinolin-4-yl)oxybenzamide;N-[(2,6-difluoro-4-pyridinyl)methyl]-2-methyl-3-(7-methylquinolin-4-yl)oxybenzamide;N-[(2,6-dimethyl-4-pyridinyl)methyl]-3-(7-methoxyquinolin-4-yl)oxy-2-methylbenzamide;2-methyl-3-(7-methylquinolin-4-yl)oxy-N-[(2,3,6-trifluoro-4-pyridinyl)methyl]benzamide has a molecular weight of 3017.38 g/mol, XLogP of 37.67, 37 rotatable bonds, 7 hydrogen bond donors, and 30 hydrogen bond acceptors.

Where does this data come from?

All data for N-[(6-chloro-3-pyridinyl)methyl]-3-(7-methoxyquinolin-4-yl)oxy-2-methylbenzamide;3-(7-chloroquinolin-4-yl)oxy-N-[(2,5-difluoro-4-pyridinyl)methyl]-2-methylbenzamide;3-(7-chloroquinolin-4-yl)oxy-N-[(2,6-difluoro-4-pyridinyl)methyl]-2-methylbenzamide;N-[(2,5-difluoro-4-pyridinyl)methyl]-2-methyl-3-(7-methylquinolin-4-yl)oxybenzamide;N-[(2,6-difluoro-4-pyridinyl)methyl]-2-methyl-3-(7-methylquinolin-4-yl)oxybenzamide;N-[(2,6-dimethyl-4-pyridinyl)methyl]-3-(7-methoxyquinolin-4-yl)oxy-2-methylbenzamide;2-methyl-3-(7-methylquinolin-4-yl)oxy-N-[(2,3,6-trifluoro-4-pyridinyl)methyl]benzamide is sourced from PubChem (CID 167548650), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).