7-amino-N-[(3R)-7-(3,8-diazabicyclo[3.2.1]octan-3-yl)-3,4-dihydro-2H-chromen-3-yl]-3-methylthieno[2,3-b]pyrazine-6-carboxamide;7-amino-N-[(3S)-7-(3,8-diazabicyclo[3.2.1]octan-3-yl)-3,4-dihydro-2H-chromen-3-yl]-3-methylthieno[2,3-b]pyrazine-6-carboxamide;3-amino-N-[(3R)-7-(3,8-diazabicyclo[3.2.1]octan-3-yl)-3,4-dihydro-2H-chromen-3-yl]-5-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-N-[(3S)-7-(3,8-diazabicyclo[3.2.1]octan-3-yl)-3,4-dihydro-2H-chromen-3-yl]-5-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-5-fluoro-6-methyl-N-[(3R)-7-piperazin-1-yl-3,4-dihydro-2H-chromen-3-yl]thieno[2,3-b]pyridine-2-carboxamide;3-amino-5-fluoro-6-methyl-N-[(3S)-7-piperazin-1-yl-3,4-dihydro-2H-chromen-3-yl]thieno[2,3-b]pyridine-2-carboxamide

C138H154F2N32O12S6 — CID 167549732

About 7-amino-N-[(3R)-7-(3,8-diazabicyclo[3.2.1]octan-3-yl)-3,4-dihydro-2H-chromen-3-yl]-3-methylthieno[2,3-b]pyrazine-6-carboxamide;7-amino-N-[(3S)-7-(3,8-diazabicyclo[3.2.1]octan-3-yl)-3,4-dihydro-2H-chromen-3-yl]-3-methylthieno[2,3-b]pyrazine-6-carboxamide;3-amino-N-[(3R)-7-(3,8-diazabicyclo[3.2.1]octan-3-yl)-3,4-dihydro-2H-chromen-3-yl]-5-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-N-[(3S)-7-(3,8-diazabicyclo[3.2.1]octan-3-yl)-3,4-dihydro-2H-chromen-3-yl]-5-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-5-fluoro-6-methyl-N-[(3R)-7-piperazin-1-yl-3,4-dihydro-2H-chromen-3-yl]thieno[2,3-b]pyridine-2-carboxamide;3-amino-5-fluoro-6-methyl-N-[(3S)-7-piperazin-1-yl-3,4-dihydro-2H-chromen-3-yl]thieno[2,3-b]pyridine-2-carboxamide

7-amino-N-[(3R)-7-(3,8-diazabicyclo[3.2.1]octan-3-yl)-3,4-dihydro-2H-chromen-3-yl]-3-methylthieno[2,3-b]pyrazine-6-carboxamide;7-amino-N-[(3S)-7-(3,8-diazabicyclo[3.2.1]octan-3-yl)-3,4-dihydro-2H-chromen-3-yl]-3-methylthieno[2,3-b]pyrazine-6-carboxamide;3-amino-N-[(3R)-7-(3,8-diazabicyclo[3.2.1]octan-3-yl)-3,4-dihydro-2H-chromen-3-yl]-5-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-N-[(3S)-7-(3,8-diazabicyclo[3.2.1]octan-3-yl)-3,4-dihydro-2H-chromen-3-yl]-5-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-5-fluoro-6-methyl-N-[(3R)-7-piperazin-1-yl-3,4-dihydro-2H-chromen-3-yl]thieno[2,3-b]pyridine-2-carboxamide;3-amino-5-fluoro-6-methyl-N-[(3S)-7-piperazin-1-yl-3,4-dihydro-2H-chromen-3-yl]thieno[2,3-b]pyridine-2-carboxamide (PubChem CID 167549732) has the molecular formula C138H154F2N32O12S6 and a molecular weight of 2683.36 g/mol. Its IUPAC name is 7-amino-N-[(3R)-7-(3,8-diazabicyclo[3.2.1]octan-3-yl)-3,4-dihydro-2H-chromen-3-yl]-3-methylthieno[2,3-b]pyrazine-6-carboxamide;7-amino-N-[(3S)-7-(3,8-diazabicyclo[3.2.1]octan-3-yl)-3,4-dihydro-2H-chromen-3-yl]-3-methylthieno[2,3-b]pyrazine-6-carboxamide;3-amino-N-[(3R)-7-(3,8-diazabicyclo[3.2.1]octan-3-yl)-3,4-dihydro-2H-chromen-3-yl]-5-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-N-[(3S)-7-(3,8-diazabicyclo[3.2.1]octan-3-yl)-3,4-dihydro-2H-chromen-3-yl]-5-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-5-fluoro-6-methyl-N-[(3R)-7-piperazin-1-yl-3,4-dihydro-2H-chromen-3-yl]thieno[2,3-b]pyridine-2-carboxamide;3-amino-5-fluoro-6-methyl-N-[(3S)-7-piperazin-1-yl-3,4-dihydro-2H-chromen-3-yl]thieno[2,3-b]pyridine-2-carboxamide.

Molecular Properties

• Compound Name: 7-amino-N-[(3R)-7-(3,8-diazabicyclo[3.2.1]octan-3-yl)-3,4-dihydro-2H-chromen-3-yl]-3-methylthieno[2,3-b]pyrazine-6-carboxamide;7-amino-N-[(3S)-7-(3,8-diazabicyclo[3.2.1]octan-3-yl)-3,4-dihydro-2H-chromen-3-yl]-3-methylthieno[2,3-b]pyrazine-6-carboxamide;3-amino-N-[(3R)-7-(3,8-diazabicyclo[3.2.1]octan-3-yl)-3,4-dihydro-2H-chromen-3-yl]-5-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-N-[(3S)-7-(3,8-diazabicyclo[3.2.1]octan-3-yl)-3,4-dihydro-2H-chromen-3-yl]-5-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-5-fluoro-6-methyl-N-[(3R)-7-piperazin-1-yl-3,4-dihydro-2H-chromen-3-yl]thieno[2,3-b]pyridine-2-carboxamide;3-amino-5-fluoro-6-methyl-N-[(3S)-7-piperazin-1-yl-3,4-dihydro-2H-chromen-3-yl]thieno[2,3-b]pyridine-2-carboxamide
• PubChem CID: 167549732
• Molecular Formula: C138H154F2N32O12S6
• Molecular Weight: 2683.36 g/mol
• Exact Mass: 2681.07
• IUPAC Name: 7-amino-N-[(3R)-7-(3,8-diazabicyclo[3.2.1]octan-3-yl)-3,4-dihydro-2H-chromen-3-yl]-3-methylthieno[2,3-b]pyrazine-6-carboxamide;7-amino-N-[(3S)-7-(3,8-diazabicyclo[3.2.1]octan-3-yl)-3,4-dihydro-2H-chromen-3-yl]-3-methylthieno[2,3-b]pyrazine-6-carboxamide;3-amino-N-[(3R)-7-(3,8-diazabicyclo[3.2.1]octan-3-yl)-3,4-dihydro-2H-chromen-3-yl]-5-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-N-[(3S)-7-(3,8-diazabicyclo[3.2.1]octan-3-yl)-3,4-dihydro-2H-chromen-3-yl]-5-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-5-fluoro-6-methyl-N-[(3R)-7-piperazin-1-yl-3,4-dihydro-2H-chromen-3-yl]thieno[2,3-b]pyridine-2-carboxamide;3-amino-5-fluoro-6-methyl-N-[(3S)-7-piperazin-1-yl-3,4-dihydro-2H-chromen-3-yl]thieno[2,3-b]pyridine-2-carboxamide
• SMILES: Cc1cnc2c(N)c(C(=O)N[C@@H]3COc4cc(N5CC6CCC(C5)N6)ccc4C3)sc2n1.Cc1cnc2c(N)c(C(=O)N[C@H]3COc4cc(N5CC6CCC(C5)N6)ccc4C3)sc2n1.Cc1cnc2sc(C(=O)N[C@@H]3COc4cc(N5CC6CCC(C5)N6)ccc4C3)c(N)c2c1.Cc1cnc2sc(C(=O)N[C@H]3COc4cc(N5CC6CCC(C5)N6)ccc4C3)c(N)c2c1.Cc1nc2sc(C(=O)N[C@@H]3COc4cc(N5CCNCC5)ccc4C3)c(N)c2cc1F.Cc1nc2sc(C(=O)N[C@H]3COc4cc(N5CCNCC5)ccc4C3)c(N)c2cc1F
• InChI: InChI=1S/2C24H27N5O2S.2C23H26N6O2S.2C22H24FN5O2S/c2*1-13-6-19-21(25)22(32-24(19)26-9-13)23(30)28-17-7-14-2-5-18(8-20(14)31-12-17)29-10-15-3-4-16(11-29)27-15;2*1-12-8-25-20-19(24)21(32-23(20)26-12)22(30)28-16-6-13-2-5-17(7-18(13)31-11-16)29-9-14-3-4-15(10-29)27-14;2*1-12-17(23)10-16-19(24)20(31-22(16)26-12)21(29)27-14-8-13-2-3-15(9-18(13)30-11-14)28-6-4-25-5-7-28/h2*2,5-6,8-9,15-17,27H,3-4,7,10-12,25H2,1H3,(H,28,30);2*2,5,7-8,14-16,27H,3-4,6,9-11,24H2,1H3,(H,28,30);2*2-3,9-10,14,25H,4-8,11,24H2,1H3,(H,27,29)/t2*15?,16?,17-;2*14?,15?,16-;2*14-/m101010/s1
• InChIKey: CGDGAKONGFDNAS-HOFQNYLRSA-N
• XLogP: 15.17
• TPSA: 580.84 Ų
• H-Bond Donors: 18
• H-Bond Acceptors: 44
• Rotatable Bonds: 18
• Heavy Atoms: 190
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2683.36
LogP ≤ 5	15.17
H-Bond Donors ≤ 5	18
H-Bond Acceptors ≤ 10	44

Frequently Asked Questions

What is the IUPAC name of 7-amino-N-[(3R)-7-(3,8-diazabicyclo[3.2.1]octan-3-yl)-3,4-dihydro-2H-chromen-3-yl]-3-methylthieno[2,3-b]pyrazine-6-carboxamide;7-amino-N-[(3S)-7-(3,8-diazabicyclo[3.2.1]octan-3-yl)-3,4-dihydro-2H-chromen-3-yl]-3-methylthieno[2,3-b]pyrazine-6-carboxamide;3-amino-N-[(3R)-7-(3,8-diazabicyclo[3.2.1]octan-3-yl)-3,4-dihydro-2H-chromen-3-yl]-5-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-N-[(3S)-7-(3,8-diazabicyclo[3.2.1]octan-3-yl)-3,4-dihydro-2H-chromen-3-yl]-5-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-5-fluoro-6-methyl-N-[(3R)-7-piperazin-1-yl-3,4-dihydro-2H-chromen-3-yl]thieno[2,3-b]pyridine-2-carboxamide;3-amino-5-fluoro-6-methyl-N-[(3S)-7-piperazin-1-yl-3,4-dihydro-2H-chromen-3-yl]thieno[2,3-b]pyridine-2-carboxamide?

The IUPAC name of 7-amino-N-[(3R)-7-(3,8-diazabicyclo[3.2.1]octan-3-yl)-3,4-dihydro-2H-chromen-3-yl]-3-methylthieno[2,3-b]pyrazine-6-carboxamide;7-amino-N-[(3S)-7-(3,8-diazabicyclo[3.2.1]octan-3-yl)-3,4-dihydro-2H-chromen-3-yl]-3-methylthieno[2,3-b]pyrazine-6-carboxamide;3-amino-N-[(3R)-7-(3,8-diazabicyclo[3.2.1]octan-3-yl)-3,4-dihydro-2H-chromen-3-yl]-5-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-N-[(3S)-7-(3,8-diazabicyclo[3.2.1]octan-3-yl)-3,4-dihydro-2H-chromen-3-yl]-5-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-5-fluoro-6-methyl-N-[(3R)-7-piperazin-1-yl-3,4-dihydro-2H-chromen-3-yl]thieno[2,3-b]pyridine-2-carboxamide;3-amino-5-fluoro-6-methyl-N-[(3S)-7-piperazin-1-yl-3,4-dihydro-2H-chromen-3-yl]thieno[2,3-b]pyridine-2-carboxamide (CID 167549732) is 7-amino-N-[(3R)-7-(3,8-diazabicyclo[3.2.1]octan-3-yl)-3,4-dihydro-2H-chromen-3-yl]-3-methylthieno[2,3-b]pyrazine-6-carboxamide;7-amino-N-[(3S)-7-(3,8-diazabicyclo[3.2.1]octan-3-yl)-3,4-dihydro-2H-chromen-3-yl]-3-methylthieno[2,3-b]pyrazine-6-carboxamide;3-amino-N-[(3R)-7-(3,8-diazabicyclo[3.2.1]octan-3-yl)-3,4-dihydro-2H-chromen-3-yl]-5-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-N-[(3S)-7-(3,8-diazabicyclo[3.2.1]octan-3-yl)-3,4-dihydro-2H-chromen-3-yl]-5-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-5-fluoro-6-methyl-N-[(3R)-7-piperazin-1-yl-3,4-dihydro-2H-chromen-3-yl]thieno[2,3-b]pyridine-2-carboxamide;3-amino-5-fluoro-6-methyl-N-[(3S)-7-piperazin-1-yl-3,4-dihydro-2H-chromen-3-yl]thieno[2,3-b]pyridine-2-carboxamide.

What is the SMILES notation for 7-amino-N-[(3R)-7-(3,8-diazabicyclo[3.2.1]octan-3-yl)-3,4-dihydro-2H-chromen-3-yl]-3-methylthieno[2,3-b]pyrazine-6-carboxamide;7-amino-N-[(3S)-7-(3,8-diazabicyclo[3.2.1]octan-3-yl)-3,4-dihydro-2H-chromen-3-yl]-3-methylthieno[2,3-b]pyrazine-6-carboxamide;3-amino-N-[(3R)-7-(3,8-diazabicyclo[3.2.1]octan-3-yl)-3,4-dihydro-2H-chromen-3-yl]-5-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-N-[(3S)-7-(3,8-diazabicyclo[3.2.1]octan-3-yl)-3,4-dihydro-2H-chromen-3-yl]-5-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-5-fluoro-6-methyl-N-[(3R)-7-piperazin-1-yl-3,4-dihydro-2H-chromen-3-yl]thieno[2,3-b]pyridine-2-carboxamide;3-amino-5-fluoro-6-methyl-N-[(3S)-7-piperazin-1-yl-3,4-dihydro-2H-chromen-3-yl]thieno[2,3-b]pyridine-2-carboxamide?

The canonical SMILES for 7-amino-N-[(3R)-7-(3,8-diazabicyclo[3.2.1]octan-3-yl)-3,4-dihydro-2H-chromen-3-yl]-3-methylthieno[2,3-b]pyrazine-6-carboxamide;7-amino-N-[(3S)-7-(3,8-diazabicyclo[3.2.1]octan-3-yl)-3,4-dihydro-2H-chromen-3-yl]-3-methylthieno[2,3-b]pyrazine-6-carboxamide;3-amino-N-[(3R)-7-(3,8-diazabicyclo[3.2.1]octan-3-yl)-3,4-dihydro-2H-chromen-3-yl]-5-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-N-[(3S)-7-(3,8-diazabicyclo[3.2.1]octan-3-yl)-3,4-dihydro-2H-chromen-3-yl]-5-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-5-fluoro-6-methyl-N-[(3R)-7-piperazin-1-yl-3,4-dihydro-2H-chromen-3-yl]thieno[2,3-b]pyridine-2-carboxamide;3-amino-5-fluoro-6-methyl-N-[(3S)-7-piperazin-1-yl-3,4-dihydro-2H-chromen-3-yl]thieno[2,3-b]pyridine-2-carboxamide is Cc1cnc2c(N)c(C(=O)N[C@@H]3COc4cc(N5CC6CCC(C5)N6)ccc4C3)sc2n1.Cc1cnc2c(N)c(C(=O)N[C@H]3COc4cc(N5CC6CCC(C5)N6)ccc4C3)sc2n1.Cc1cnc2sc(C(=O)N[C@@H]3COc4cc(N5CC6CCC(C5)N6)ccc4C3)c(N)c2c1.Cc1cnc2sc(C(=O)N[C@H]3COc4cc(N5CC6CCC(C5)N6)ccc4C3)c(N)c2c1.Cc1nc2sc(C(=O)N[C@@H]3COc4cc(N5CCNCC5)ccc4C3)c(N)c2cc1F.Cc1nc2sc(C(=O)N[C@H]3COc4cc(N5CCNCC5)ccc4C3)c(N)c2cc1F.

What is the InChIKey of 7-amino-N-[(3R)-7-(3,8-diazabicyclo[3.2.1]octan-3-yl)-3,4-dihydro-2H-chromen-3-yl]-3-methylthieno[2,3-b]pyrazine-6-carboxamide;7-amino-N-[(3S)-7-(3,8-diazabicyclo[3.2.1]octan-3-yl)-3,4-dihydro-2H-chromen-3-yl]-3-methylthieno[2,3-b]pyrazine-6-carboxamide;3-amino-N-[(3R)-7-(3,8-diazabicyclo[3.2.1]octan-3-yl)-3,4-dihydro-2H-chromen-3-yl]-5-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-N-[(3S)-7-(3,8-diazabicyclo[3.2.1]octan-3-yl)-3,4-dihydro-2H-chromen-3-yl]-5-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-5-fluoro-6-methyl-N-[(3R)-7-piperazin-1-yl-3,4-dihydro-2H-chromen-3-yl]thieno[2,3-b]pyridine-2-carboxamide;3-amino-5-fluoro-6-methyl-N-[(3S)-7-piperazin-1-yl-3,4-dihydro-2H-chromen-3-yl]thieno[2,3-b]pyridine-2-carboxamide?

The InChIKey is CGDGAKONGFDNAS-HOFQNYLRSA-N. The full InChI is InChI=1S/2C24H27N5O2S.2C23H26N6O2S.2C22H24FN5O2S/c2*1-13-6-19-21(25)22(32-24(19)26-9-13)23(30)28-17-7-14-2-5-18(8-20(14)31-12-17)29-10-15-3-4-16(11-29)27-15;2*1-12-8-25-20-19(24)21(32-23(20)26-12)22(30)28-16-6-13-2-5-17(7-18(13)31-11-16)29-9-14-3-4-15(10-29)27-14;2*1-12-17(23)10-16-19(24)20(31-22(16)26-12)21(29)27-14-8-13-2-3-15(9-18(13)30-11-14)28-6-4-25-5-7-28/h2*2,5-6,8-9,15-17,27H,3-4,7,10-12,25H2,1H3,(H,28,30);2*2,5,7-8,14-16,27H,3-4,6,9-11,24H2,1H3,(H,28,30);2*2-3,9-10,14,25H,4-8,11,24H2,1H3,(H,27,29)/t2*15?,16?,17-;2*14?,15?,16-;2*14-/m101010/s1.

What are the key properties of 7-amino-N-[(3R)-7-(3,8-diazabicyclo[3.2.1]octan-3-yl)-3,4-dihydro-2H-chromen-3-yl]-3-methylthieno[2,3-b]pyrazine-6-carboxamide;7-amino-N-[(3S)-7-(3,8-diazabicyclo[3.2.1]octan-3-yl)-3,4-dihydro-2H-chromen-3-yl]-3-methylthieno[2,3-b]pyrazine-6-carboxamide;3-amino-N-[(3R)-7-(3,8-diazabicyclo[3.2.1]octan-3-yl)-3,4-dihydro-2H-chromen-3-yl]-5-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-N-[(3S)-7-(3,8-diazabicyclo[3.2.1]octan-3-yl)-3,4-dihydro-2H-chromen-3-yl]-5-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-5-fluoro-6-methyl-N-[(3R)-7-piperazin-1-yl-3,4-dihydro-2H-chromen-3-yl]thieno[2,3-b]pyridine-2-carboxamide;3-amino-5-fluoro-6-methyl-N-[(3S)-7-piperazin-1-yl-3,4-dihydro-2H-chromen-3-yl]thieno[2,3-b]pyridine-2-carboxamide?

7-amino-N-[(3R)-7-(3,8-diazabicyclo[3.2.1]octan-3-yl)-3,4-dihydro-2H-chromen-3-yl]-3-methylthieno[2,3-b]pyrazine-6-carboxamide;7-amino-N-[(3S)-7-(3,8-diazabicyclo[3.2.1]octan-3-yl)-3,4-dihydro-2H-chromen-3-yl]-3-methylthieno[2,3-b]pyrazine-6-carboxamide;3-amino-N-[(3R)-7-(3,8-diazabicyclo[3.2.1]octan-3-yl)-3,4-dihydro-2H-chromen-3-yl]-5-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-N-[(3S)-7-(3,8-diazabicyclo[3.2.1]octan-3-yl)-3,4-dihydro-2H-chromen-3-yl]-5-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-5-fluoro-6-methyl-N-[(3R)-7-piperazin-1-yl-3,4-dihydro-2H-chromen-3-yl]thieno[2,3-b]pyridine-2-carboxamide;3-amino-5-fluoro-6-methyl-N-[(3S)-7-piperazin-1-yl-3,4-dihydro-2H-chromen-3-yl]thieno[2,3-b]pyridine-2-carboxamide has a molecular weight of 2683.36 g/mol, XLogP of 15.17, 18 rotatable bonds, 18 hydrogen bond donors, and 44 hydrogen bond acceptors.

Where does this data come from?

All data for 7-amino-N-[(3R)-7-(3,8-diazabicyclo[3.2.1]octan-3-yl)-3,4-dihydro-2H-chromen-3-yl]-3-methylthieno[2,3-b]pyrazine-6-carboxamide;7-amino-N-[(3S)-7-(3,8-diazabicyclo[3.2.1]octan-3-yl)-3,4-dihydro-2H-chromen-3-yl]-3-methylthieno[2,3-b]pyrazine-6-carboxamide;3-amino-N-[(3R)-7-(3,8-diazabicyclo[3.2.1]octan-3-yl)-3,4-dihydro-2H-chromen-3-yl]-5-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-N-[(3S)-7-(3,8-diazabicyclo[3.2.1]octan-3-yl)-3,4-dihydro-2H-chromen-3-yl]-5-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-5-fluoro-6-methyl-N-[(3R)-7-piperazin-1-yl-3,4-dihydro-2H-chromen-3-yl]thieno[2,3-b]pyridine-2-carboxamide;3-amino-5-fluoro-6-methyl-N-[(3S)-7-piperazin-1-yl-3,4-dihydro-2H-chromen-3-yl]thieno[2,3-b]pyridine-2-carboxamide is sourced from PubChem (CID 167549732), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).