2-methoxy-7-(8-methylnaphthalen-1-yl)-4-phenylmethoxy-7,8-dihydro-5H-pyrano[4,3-d]pyrimidine;4-methyl-7-(8-methylnaphthalen-1-yl)-2-[[(2S)-1-methylpyrrolidin-2-yl]methoxy]-7,8-dihydro-5H-pyrano[4,3-d]pyrimidine;7-(8-methylnaphthalen-1-yl)-2-[[(2S)-1-methylpyrrolidin-2-yl]methoxy]-4-phenylmethoxy-7,8-dihydro-5H-pyrano[4,3-d]pyrimidine;7-(8-methylnaphthalen-1-yl)-2-[[(2S)-1-methylpyrrolidin-2-yl]methoxy]-3,5,7,8-tetrahydropyrano[4,3-d]pyrimidin-4-one;7-(8-methylnaphthalen-1-yl)-2-methylsulfonyl-4-phenylmethoxy-7,8-dihydro-5H-pyrano[4,3-d]pyrimidine

C132H137N13O15S — CID 167564945

About 2-methoxy-7-(8-methylnaphthalen-1-yl)-4-phenylmethoxy-7,8-dihydro-5H-pyrano[4,3-d]pyrimidine;4-methyl-7-(8-methylnaphthalen-1-yl)-2-[[(2S)-1-methylpyrrolidin-2-yl]methoxy]-7,8-dihydro-5H-pyrano[4,3-d]pyrimidine;7-(8-methylnaphthalen-1-yl)-2-[[(2S)-1-methylpyrrolidin-2-yl]methoxy]-4-phenylmethoxy-7,8-dihydro-5H-pyrano[4,3-d]pyrimidine;7-(8-methylnaphthalen-1-yl)-2-[[(2S)-1-methylpyrrolidin-2-yl]methoxy]-3,5,7,8-tetrahydropyrano[4,3-d]pyrimidin-4-one;7-(8-methylnaphthalen-1-yl)-2-methylsulfonyl-4-phenylmethoxy-7,8-dihydro-5H-pyrano[4,3-d]pyrimidine

2-methoxy-7-(8-methylnaphthalen-1-yl)-4-phenylmethoxy-7,8-dihydro-5H-pyrano[4,3-d]pyrimidine;4-methyl-7-(8-methylnaphthalen-1-yl)-2-[[(2S)-1-methylpyrrolidin-2-yl]methoxy]-7,8-dihydro-5H-pyrano[4,3-d]pyrimidine;7-(8-methylnaphthalen-1-yl)-2-[[(2S)-1-methylpyrrolidin-2-yl]methoxy]-4-phenylmethoxy-7,8-dihydro-5H-pyrano[4,3-d]pyrimidine;7-(8-methylnaphthalen-1-yl)-2-[[(2S)-1-methylpyrrolidin-2-yl]methoxy]-3,5,7,8-tetrahydropyrano[4,3-d]pyrimidin-4-one;7-(8-methylnaphthalen-1-yl)-2-methylsulfonyl-4-phenylmethoxy-7,8-dihydro-5H-pyrano[4,3-d]pyrimidine (PubChem CID 167564945) has the molecular formula C132H137N13O15S and a molecular weight of 2177.69 g/mol. Its IUPAC name is 2-methoxy-7-(8-methylnaphthalen-1-yl)-4-phenylmethoxy-7,8-dihydro-5H-pyrano[4,3-d]pyrimidine;4-methyl-7-(8-methylnaphthalen-1-yl)-2-[[(2S)-1-methylpyrrolidin-2-yl]methoxy]-7,8-dihydro-5H-pyrano[4,3-d]pyrimidine;7-(8-methylnaphthalen-1-yl)-2-[[(2S)-1-methylpyrrolidin-2-yl]methoxy]-4-phenylmethoxy-7,8-dihydro-5H-pyrano[4,3-d]pyrimidine;7-(8-methylnaphthalen-1-yl)-2-[[(2S)-1-methylpyrrolidin-2-yl]methoxy]-3,5,7,8-tetrahydropyrano[4,3-d]pyrimidin-4-one;7-(8-methylnaphthalen-1-yl)-2-methylsulfonyl-4-phenylmethoxy-7,8-dihydro-5H-pyrano[4,3-d]pyrimidine.

Molecular Properties

• Compound Name: 2-methoxy-7-(8-methylnaphthalen-1-yl)-4-phenylmethoxy-7,8-dihydro-5H-pyrano[4,3-d]pyrimidine;4-methyl-7-(8-methylnaphthalen-1-yl)-2-[[(2S)-1-methylpyrrolidin-2-yl]methoxy]-7,8-dihydro-5H-pyrano[4,3-d]pyrimidine;7-(8-methylnaphthalen-1-yl)-2-[[(2S)-1-methylpyrrolidin-2-yl]methoxy]-4-phenylmethoxy-7,8-dihydro-5H-pyrano[4,3-d]pyrimidine;7-(8-methylnaphthalen-1-yl)-2-[[(2S)-1-methylpyrrolidin-2-yl]methoxy]-3,5,7,8-tetrahydropyrano[4,3-d]pyrimidin-4-one;7-(8-methylnaphthalen-1-yl)-2-methylsulfonyl-4-phenylmethoxy-7,8-dihydro-5H-pyrano[4,3-d]pyrimidine
• PubChem CID: 167564945
• Molecular Formula: C132H137N13O15S
• Molecular Weight: 2177.69 g/mol
• Exact Mass: 2176.01
• IUPAC Name: 2-methoxy-7-(8-methylnaphthalen-1-yl)-4-phenylmethoxy-7,8-dihydro-5H-pyrano[4,3-d]pyrimidine;4-methyl-7-(8-methylnaphthalen-1-yl)-2-[[(2S)-1-methylpyrrolidin-2-yl]methoxy]-7,8-dihydro-5H-pyrano[4,3-d]pyrimidine;7-(8-methylnaphthalen-1-yl)-2-[[(2S)-1-methylpyrrolidin-2-yl]methoxy]-4-phenylmethoxy-7,8-dihydro-5H-pyrano[4,3-d]pyrimidine;7-(8-methylnaphthalen-1-yl)-2-[[(2S)-1-methylpyrrolidin-2-yl]methoxy]-3,5,7,8-tetrahydropyrano[4,3-d]pyrimidin-4-one;7-(8-methylnaphthalen-1-yl)-2-methylsulfonyl-4-phenylmethoxy-7,8-dihydro-5H-pyrano[4,3-d]pyrimidine
• SMILES: COc1nc2c(c(OCc3ccccc3)n1)COC(c1cccc3cccc(C)c13)C2.Cc1cccc2cccc(C3Cc4nc(OC[C@@H]5CCCN5C)[nH]c(=O)c4CO3)c12.Cc1cccc2cccc(C3Cc4nc(OC[C@@H]5CCCN5C)nc(OCc5ccccc5)c4CO3)c12.Cc1cccc2cccc(C3Cc4nc(S(C)(=O)=O)nc(OCc5ccccc5)c4CO3)c12.Cc1nc(OC[C@@H]2CCCN2C)nc2c1COC(c1cccc3cccc(C)c13)C2
• InChI: InChI=1S/C31H33N3O3.C26H24N2O4S.C26H24N2O3.C25H29N3O2.C24H27N3O3/c1-21-9-6-12-23-13-7-15-25(29(21)23)28-17-27-26(20-35-28)30(36-18-22-10-4-3-5-11-22)33-31(32-27)37-19-24-14-8-16-34(24)2;1-17-8-6-11-19-12-7-13-20(24(17)19)23-14-22-21(16-31-23)25(28-26(27-22)33(2,29)30)32-15-18-9-4-3-5-10-18;1-17-8-6-11-19-12-7-13-20(24(17)19)23-14-22-21(16-30-23)25(28-26(27-22)29-2)31-15-18-9-4-3-5-10-18;1-16-7-4-8-18-9-5-11-20(24(16)18)23-13-22-21(15-29-23)17(2)26-25(27-22)30-14-19-10-6-12-28(19)3;1-15-6-3-7-16-8-4-10-18(22(15)16)21-12-20-19(14-29-21)23(28)26-24(25-20)30-13-17-9-5-11-27(17)2/h3-7,9-13,15,24,28H,8,14,16-20H2,1-2H3;3-13,23H,14-16H2,1-2H3;3-13,23H,14-16H2,1-2H3;4-5,7-9,11,19,23H,6,10,12-15H2,1-3H3;3-4,6-8,10,17,21H,5,9,11-14H2,1-2H3,(H,25,26,28)/t24-,28?;;;19-,23?;17-,21?/m0..00/s1
• InChIKey: FDOLEILFOFSYBQ-RDEJFDAQSA-N
• XLogP: 23.93
• TPSA: 303.49 Ų
• H-Bond Donors: 1
• H-Bond Acceptors: 27
• Rotatable Bonds: 25
• Heavy Atoms: 161
• Complexity: —

Lipinski Rule of Five

3 violations

Rule	Value
MW ≤ 500	2177.69
LogP ≤ 5	23.93
H-Bond Donors ≤ 5	1
H-Bond Acceptors ≤ 10	27

Frequently Asked Questions

What is the IUPAC name of 2-methoxy-7-(8-methylnaphthalen-1-yl)-4-phenylmethoxy-7,8-dihydro-5H-pyrano[4,3-d]pyrimidine;4-methyl-7-(8-methylnaphthalen-1-yl)-2-[[(2S)-1-methylpyrrolidin-2-yl]methoxy]-7,8-dihydro-5H-pyrano[4,3-d]pyrimidine;7-(8-methylnaphthalen-1-yl)-2-[[(2S)-1-methylpyrrolidin-2-yl]methoxy]-4-phenylmethoxy-7,8-dihydro-5H-pyrano[4,3-d]pyrimidine;7-(8-methylnaphthalen-1-yl)-2-[[(2S)-1-methylpyrrolidin-2-yl]methoxy]-3,5,7,8-tetrahydropyrano[4,3-d]pyrimidin-4-one;7-(8-methylnaphthalen-1-yl)-2-methylsulfonyl-4-phenylmethoxy-7,8-dihydro-5H-pyrano[4,3-d]pyrimidine?

The IUPAC name of 2-methoxy-7-(8-methylnaphthalen-1-yl)-4-phenylmethoxy-7,8-dihydro-5H-pyrano[4,3-d]pyrimidine;4-methyl-7-(8-methylnaphthalen-1-yl)-2-[[(2S)-1-methylpyrrolidin-2-yl]methoxy]-7,8-dihydro-5H-pyrano[4,3-d]pyrimidine;7-(8-methylnaphthalen-1-yl)-2-[[(2S)-1-methylpyrrolidin-2-yl]methoxy]-4-phenylmethoxy-7,8-dihydro-5H-pyrano[4,3-d]pyrimidine;7-(8-methylnaphthalen-1-yl)-2-[[(2S)-1-methylpyrrolidin-2-yl]methoxy]-3,5,7,8-tetrahydropyrano[4,3-d]pyrimidin-4-one;7-(8-methylnaphthalen-1-yl)-2-methylsulfonyl-4-phenylmethoxy-7,8-dihydro-5H-pyrano[4,3-d]pyrimidine (CID 167564945) is 2-methoxy-7-(8-methylnaphthalen-1-yl)-4-phenylmethoxy-7,8-dihydro-5H-pyrano[4,3-d]pyrimidine;4-methyl-7-(8-methylnaphthalen-1-yl)-2-[[(2S)-1-methylpyrrolidin-2-yl]methoxy]-7,8-dihydro-5H-pyrano[4,3-d]pyrimidine;7-(8-methylnaphthalen-1-yl)-2-[[(2S)-1-methylpyrrolidin-2-yl]methoxy]-4-phenylmethoxy-7,8-dihydro-5H-pyrano[4,3-d]pyrimidine;7-(8-methylnaphthalen-1-yl)-2-[[(2S)-1-methylpyrrolidin-2-yl]methoxy]-3,5,7,8-tetrahydropyrano[4,3-d]pyrimidin-4-one;7-(8-methylnaphthalen-1-yl)-2-methylsulfonyl-4-phenylmethoxy-7,8-dihydro-5H-pyrano[4,3-d]pyrimidine.

What is the SMILES notation for 2-methoxy-7-(8-methylnaphthalen-1-yl)-4-phenylmethoxy-7,8-dihydro-5H-pyrano[4,3-d]pyrimidine;4-methyl-7-(8-methylnaphthalen-1-yl)-2-[[(2S)-1-methylpyrrolidin-2-yl]methoxy]-7,8-dihydro-5H-pyrano[4,3-d]pyrimidine;7-(8-methylnaphthalen-1-yl)-2-[[(2S)-1-methylpyrrolidin-2-yl]methoxy]-4-phenylmethoxy-7,8-dihydro-5H-pyrano[4,3-d]pyrimidine;7-(8-methylnaphthalen-1-yl)-2-[[(2S)-1-methylpyrrolidin-2-yl]methoxy]-3,5,7,8-tetrahydropyrano[4,3-d]pyrimidin-4-one;7-(8-methylnaphthalen-1-yl)-2-methylsulfonyl-4-phenylmethoxy-7,8-dihydro-5H-pyrano[4,3-d]pyrimidine?

The canonical SMILES for 2-methoxy-7-(8-methylnaphthalen-1-yl)-4-phenylmethoxy-7,8-dihydro-5H-pyrano[4,3-d]pyrimidine;4-methyl-7-(8-methylnaphthalen-1-yl)-2-[[(2S)-1-methylpyrrolidin-2-yl]methoxy]-7,8-dihydro-5H-pyrano[4,3-d]pyrimidine;7-(8-methylnaphthalen-1-yl)-2-[[(2S)-1-methylpyrrolidin-2-yl]methoxy]-4-phenylmethoxy-7,8-dihydro-5H-pyrano[4,3-d]pyrimidine;7-(8-methylnaphthalen-1-yl)-2-[[(2S)-1-methylpyrrolidin-2-yl]methoxy]-3,5,7,8-tetrahydropyrano[4,3-d]pyrimidin-4-one;7-(8-methylnaphthalen-1-yl)-2-methylsulfonyl-4-phenylmethoxy-7,8-dihydro-5H-pyrano[4,3-d]pyrimidine is COc1nc2c(c(OCc3ccccc3)n1)COC(c1cccc3cccc(C)c13)C2.Cc1cccc2cccc(C3Cc4nc(OC[C@@H]5CCCN5C)[nH]c(=O)c4CO3)c12.Cc1cccc2cccc(C3Cc4nc(OC[C@@H]5CCCN5C)nc(OCc5ccccc5)c4CO3)c12.Cc1cccc2cccc(C3Cc4nc(S(C)(=O)=O)nc(OCc5ccccc5)c4CO3)c12.Cc1nc(OC[C@@H]2CCCN2C)nc2c1COC(c1cccc3cccc(C)c13)C2.

What is the InChIKey of 2-methoxy-7-(8-methylnaphthalen-1-yl)-4-phenylmethoxy-7,8-dihydro-5H-pyrano[4,3-d]pyrimidine;4-methyl-7-(8-methylnaphthalen-1-yl)-2-[[(2S)-1-methylpyrrolidin-2-yl]methoxy]-7,8-dihydro-5H-pyrano[4,3-d]pyrimidine;7-(8-methylnaphthalen-1-yl)-2-[[(2S)-1-methylpyrrolidin-2-yl]methoxy]-4-phenylmethoxy-7,8-dihydro-5H-pyrano[4,3-d]pyrimidine;7-(8-methylnaphthalen-1-yl)-2-[[(2S)-1-methylpyrrolidin-2-yl]methoxy]-3,5,7,8-tetrahydropyrano[4,3-d]pyrimidin-4-one;7-(8-methylnaphthalen-1-yl)-2-methylsulfonyl-4-phenylmethoxy-7,8-dihydro-5H-pyrano[4,3-d]pyrimidine?

The InChIKey is FDOLEILFOFSYBQ-RDEJFDAQSA-N. The full InChI is InChI=1S/C31H33N3O3.C26H24N2O4S.C26H24N2O3.C25H29N3O2.C24H27N3O3/c1-21-9-6-12-23-13-7-15-25(29(21)23)28-17-27-26(20-35-28)30(36-18-22-10-4-3-5-11-22)33-31(32-27)37-19-24-14-8-16-34(24)2;1-17-8-6-11-19-12-7-13-20(24(17)19)23-14-22-21(16-31-23)25(28-26(27-22)33(2,29)30)32-15-18-9-4-3-5-10-18;1-17-8-6-11-19-12-7-13-20(24(17)19)23-14-22-21(16-30-23)25(28-26(27-22)29-2)31-15-18-9-4-3-5-10-18;1-16-7-4-8-18-9-5-11-20(24(16)18)23-13-22-21(15-29-23)17(2)26-25(27-22)30-14-19-10-6-12-28(19)3;1-15-6-3-7-16-8-4-10-18(22(15)16)21-12-20-19(14-29-21)23(28)26-24(25-20)30-13-17-9-5-11-27(17)2/h3-7,9-13,15,24,28H,8,14,16-20H2,1-2H3;3-13,23H,14-16H2,1-2H3;3-13,23H,14-16H2,1-2H3;4-5,7-9,11,19,23H,6,10,12-15H2,1-3H3;3-4,6-8,10,17,21H,5,9,11-14H2,1-2H3,(H,25,26,28)/t24-,28?;;;19-,23?;17-,21?/m0..00/s1.

What are the key properties of 2-methoxy-7-(8-methylnaphthalen-1-yl)-4-phenylmethoxy-7,8-dihydro-5H-pyrano[4,3-d]pyrimidine;4-methyl-7-(8-methylnaphthalen-1-yl)-2-[[(2S)-1-methylpyrrolidin-2-yl]methoxy]-7,8-dihydro-5H-pyrano[4,3-d]pyrimidine;7-(8-methylnaphthalen-1-yl)-2-[[(2S)-1-methylpyrrolidin-2-yl]methoxy]-4-phenylmethoxy-7,8-dihydro-5H-pyrano[4,3-d]pyrimidine;7-(8-methylnaphthalen-1-yl)-2-[[(2S)-1-methylpyrrolidin-2-yl]methoxy]-3,5,7,8-tetrahydropyrano[4,3-d]pyrimidin-4-one;7-(8-methylnaphthalen-1-yl)-2-methylsulfonyl-4-phenylmethoxy-7,8-dihydro-5H-pyrano[4,3-d]pyrimidine?

2-methoxy-7-(8-methylnaphthalen-1-yl)-4-phenylmethoxy-7,8-dihydro-5H-pyrano[4,3-d]pyrimidine;4-methyl-7-(8-methylnaphthalen-1-yl)-2-[[(2S)-1-methylpyrrolidin-2-yl]methoxy]-7,8-dihydro-5H-pyrano[4,3-d]pyrimidine;7-(8-methylnaphthalen-1-yl)-2-[[(2S)-1-methylpyrrolidin-2-yl]methoxy]-4-phenylmethoxy-7,8-dihydro-5H-pyrano[4,3-d]pyrimidine;7-(8-methylnaphthalen-1-yl)-2-[[(2S)-1-methylpyrrolidin-2-yl]methoxy]-3,5,7,8-tetrahydropyrano[4,3-d]pyrimidin-4-one;7-(8-methylnaphthalen-1-yl)-2-methylsulfonyl-4-phenylmethoxy-7,8-dihydro-5H-pyrano[4,3-d]pyrimidine has a molecular weight of 2177.69 g/mol, XLogP of 23.93, 25 rotatable bonds, 1 hydrogen bond donors, and 27 hydrogen bond acceptors.

Where does this data come from?

All data for 2-methoxy-7-(8-methylnaphthalen-1-yl)-4-phenylmethoxy-7,8-dihydro-5H-pyrano[4,3-d]pyrimidine;4-methyl-7-(8-methylnaphthalen-1-yl)-2-[[(2S)-1-methylpyrrolidin-2-yl]methoxy]-7,8-dihydro-5H-pyrano[4,3-d]pyrimidine;7-(8-methylnaphthalen-1-yl)-2-[[(2S)-1-methylpyrrolidin-2-yl]methoxy]-4-phenylmethoxy-7,8-dihydro-5H-pyrano[4,3-d]pyrimidine;7-(8-methylnaphthalen-1-yl)-2-[[(2S)-1-methylpyrrolidin-2-yl]methoxy]-3,5,7,8-tetrahydropyrano[4,3-d]pyrimidin-4-one;7-(8-methylnaphthalen-1-yl)-2-methylsulfonyl-4-phenylmethoxy-7,8-dihydro-5H-pyrano[4,3-d]pyrimidine is sourced from PubChem (CID 167564945), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).