4-(4-amino-2-fluorophenoxy)-7-methoxy-N-methylquinoline-6-carboxamide;1-[4-(4-amino-2-fluorophenoxy)-7-methoxyquinolin-6-yl]butan-2-one;4-(4-aminophenoxy)-7-methoxy-N-methylquinoline-6-carboxamide;4-[7-[1-(difluoromethyl)pyrazol-4-yl]quinolin-4-yl]oxyaniline;6-(6,7-dimethoxyquinolin-4-yl)oxy-5-fluoropyridin-3-amine;3-fluoro-4-[(6-methoxy-1,7-naphthyridin-4-yl)oxy]aniline

C106H92F6N18O15 — CID 167570326

About 4-(4-amino-2-fluorophenoxy)-7-methoxy-N-methylquinoline-6-carboxamide;1-[4-(4-amino-2-fluorophenoxy)-7-methoxyquinolin-6-yl]butan-2-one;4-(4-aminophenoxy)-7-methoxy-N-methylquinoline-6-carboxamide;4-[7-[1-(difluoromethyl)pyrazol-4-yl]quinolin-4-yl]oxyaniline;6-(6,7-dimethoxyquinolin-4-yl)oxy-5-fluoropyridin-3-amine;3-fluoro-4-[(6-methoxy-1,7-naphthyridin-4-yl)oxy]aniline

4-(4-amino-2-fluorophenoxy)-7-methoxy-N-methylquinoline-6-carboxamide;1-[4-(4-amino-2-fluorophenoxy)-7-methoxyquinolin-6-yl]butan-2-one;4-(4-aminophenoxy)-7-methoxy-N-methylquinoline-6-carboxamide;4-[7-[1-(difluoromethyl)pyrazol-4-yl]quinolin-4-yl]oxyaniline;6-(6,7-dimethoxyquinolin-4-yl)oxy-5-fluoropyridin-3-amine;3-fluoro-4-[(6-methoxy-1,7-naphthyridin-4-yl)oxy]aniline (PubChem CID 167570326) has the molecular formula C106H92F6N18O15 and a molecular weight of 1972.00 g/mol. Its IUPAC name is 4-(4-amino-2-fluorophenoxy)-7-methoxy-N-methylquinoline-6-carboxamide;1-[4-(4-amino-2-fluorophenoxy)-7-methoxyquinolin-6-yl]butan-2-one;4-(4-aminophenoxy)-7-methoxy-N-methylquinoline-6-carboxamide;4-[7-[1-(difluoromethyl)pyrazol-4-yl]quinolin-4-yl]oxyaniline;6-(6,7-dimethoxyquinolin-4-yl)oxy-5-fluoropyridin-3-amine;3-fluoro-4-[(6-methoxy-1,7-naphthyridin-4-yl)oxy]aniline.

Molecular Properties

• Compound Name: 4-(4-amino-2-fluorophenoxy)-7-methoxy-N-methylquinoline-6-carboxamide;1-[4-(4-amino-2-fluorophenoxy)-7-methoxyquinolin-6-yl]butan-2-one;4-(4-aminophenoxy)-7-methoxy-N-methylquinoline-6-carboxamide;4-[7-[1-(difluoromethyl)pyrazol-4-yl]quinolin-4-yl]oxyaniline;6-(6,7-dimethoxyquinolin-4-yl)oxy-5-fluoropyridin-3-amine;3-fluoro-4-[(6-methoxy-1,7-naphthyridin-4-yl)oxy]aniline
• PubChem CID: 167570326
• Molecular Formula: C106H92F6N18O15
• Molecular Weight: 1972.00 g/mol
• Exact Mass: 1970.69
• IUPAC Name: 4-(4-amino-2-fluorophenoxy)-7-methoxy-N-methylquinoline-6-carboxamide;1-[4-(4-amino-2-fluorophenoxy)-7-methoxyquinolin-6-yl]butan-2-one;4-(4-aminophenoxy)-7-methoxy-N-methylquinoline-6-carboxamide;4-[7-[1-(difluoromethyl)pyrazol-4-yl]quinolin-4-yl]oxyaniline;6-(6,7-dimethoxyquinolin-4-yl)oxy-5-fluoropyridin-3-amine;3-fluoro-4-[(6-methoxy-1,7-naphthyridin-4-yl)oxy]aniline
• SMILES: CCC(=O)Cc1cc2c(Oc3ccc(N)cc3F)ccnc2cc1OC.CNC(=O)c1cc2c(Oc3ccc(N)cc3)ccnc2cc1OC.CNC(=O)c1cc2c(Oc3ccc(N)cc3F)ccnc2cc1OC.COc1cc2c(Oc3ccc(N)cc3F)ccnc2cn1.COc1cc2nccc(Oc3ncc(N)cc3F)c2cc1OC.Nc1ccc(Oc2ccnc3cc(-c4cnn(C(F)F)c4)ccc23)cc1
• InChI: InChI=1S/C20H19FN2O3.C19H14F2N4O.C18H16FN3O3.C18H17N3O3.C16H14FN3O3.C15H12FN3O2/c1-3-14(24)8-12-9-15-17(11-20(12)25-2)23-7-6-18(15)26-19-5-4-13(22)10-16(19)21;20-19(21)25-11-13(10-24-25)12-1-6-16-17(9-12)23-8-7-18(16)26-15-4-2-14(22)3-5-15;1-21-18(23)12-8-11-14(9-17(12)24-2)22-6-5-15(11)25-16-4-3-10(20)7-13(16)19;1-20-18(22)14-9-13-15(10-17(14)23-2)21-8-7-16(13)24-12-5-3-11(19)4-6-12;1-21-14-6-10-12(7-15(14)22-2)19-4-3-13(10)23-16-11(17)5-9(18)8-20-16;1-20-15-7-10-12(8-19-15)18-5-4-13(10)21-14-3-2-9(17)6-11(14)16/h4-7,9-11H,3,8,22H2,1-2H3;1-11,19H,22H2;3-9H,20H2,1-2H3,(H,21,23);3-10H,19H2,1-2H3,(H,20,22);3-8H,18H2,1-2H3;2-8H,17H2,1H3
• InChIKey: FUYHSMUFZPBIST-UHFFFAOYSA-N
• XLogP: 21.55
• TPSA: 463.09 Ų
• H-Bond Donors: 8
• H-Bond Acceptors: 31
• Rotatable Bonds: 25
• Heavy Atoms: 145
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	1972.00
LogP ≤ 5	21.55
H-Bond Donors ≤ 5	8
H-Bond Acceptors ≤ 10	31

Computed Properties (RDKit)

• Structural Alerts: {'alert_name': 'anil_no_alk(40)', 'substructure': 'N/A'}, {'alert_name': 'aniline', 'substructure': 'N/A'}

Frequently Asked Questions

What is the IUPAC name of 4-(4-amino-2-fluorophenoxy)-7-methoxy-N-methylquinoline-6-carboxamide;1-[4-(4-amino-2-fluorophenoxy)-7-methoxyquinolin-6-yl]butan-2-one;4-(4-aminophenoxy)-7-methoxy-N-methylquinoline-6-carboxamide;4-[7-[1-(difluoromethyl)pyrazol-4-yl]quinolin-4-yl]oxyaniline;6-(6,7-dimethoxyquinolin-4-yl)oxy-5-fluoropyridin-3-amine;3-fluoro-4-[(6-methoxy-1,7-naphthyridin-4-yl)oxy]aniline?

The IUPAC name of 4-(4-amino-2-fluorophenoxy)-7-methoxy-N-methylquinoline-6-carboxamide;1-[4-(4-amino-2-fluorophenoxy)-7-methoxyquinolin-6-yl]butan-2-one;4-(4-aminophenoxy)-7-methoxy-N-methylquinoline-6-carboxamide;4-[7-[1-(difluoromethyl)pyrazol-4-yl]quinolin-4-yl]oxyaniline;6-(6,7-dimethoxyquinolin-4-yl)oxy-5-fluoropyridin-3-amine;3-fluoro-4-[(6-methoxy-1,7-naphthyridin-4-yl)oxy]aniline (CID 167570326) is 4-(4-amino-2-fluorophenoxy)-7-methoxy-N-methylquinoline-6-carboxamide;1-[4-(4-amino-2-fluorophenoxy)-7-methoxyquinolin-6-yl]butan-2-one;4-(4-aminophenoxy)-7-methoxy-N-methylquinoline-6-carboxamide;4-[7-[1-(difluoromethyl)pyrazol-4-yl]quinolin-4-yl]oxyaniline;6-(6,7-dimethoxyquinolin-4-yl)oxy-5-fluoropyridin-3-amine;3-fluoro-4-[(6-methoxy-1,7-naphthyridin-4-yl)oxy]aniline.

What is the SMILES notation for 4-(4-amino-2-fluorophenoxy)-7-methoxy-N-methylquinoline-6-carboxamide;1-[4-(4-amino-2-fluorophenoxy)-7-methoxyquinolin-6-yl]butan-2-one;4-(4-aminophenoxy)-7-methoxy-N-methylquinoline-6-carboxamide;4-[7-[1-(difluoromethyl)pyrazol-4-yl]quinolin-4-yl]oxyaniline;6-(6,7-dimethoxyquinolin-4-yl)oxy-5-fluoropyridin-3-amine;3-fluoro-4-[(6-methoxy-1,7-naphthyridin-4-yl)oxy]aniline?

The canonical SMILES for 4-(4-amino-2-fluorophenoxy)-7-methoxy-N-methylquinoline-6-carboxamide;1-[4-(4-amino-2-fluorophenoxy)-7-methoxyquinolin-6-yl]butan-2-one;4-(4-aminophenoxy)-7-methoxy-N-methylquinoline-6-carboxamide;4-[7-[1-(difluoromethyl)pyrazol-4-yl]quinolin-4-yl]oxyaniline;6-(6,7-dimethoxyquinolin-4-yl)oxy-5-fluoropyridin-3-amine;3-fluoro-4-[(6-methoxy-1,7-naphthyridin-4-yl)oxy]aniline is CCC(=O)Cc1cc2c(Oc3ccc(N)cc3F)ccnc2cc1OC.CNC(=O)c1cc2c(Oc3ccc(N)cc3)ccnc2cc1OC.CNC(=O)c1cc2c(Oc3ccc(N)cc3F)ccnc2cc1OC.COc1cc2c(Oc3ccc(N)cc3F)ccnc2cn1.COc1cc2nccc(Oc3ncc(N)cc3F)c2cc1OC.Nc1ccc(Oc2ccnc3cc(-c4cnn(C(F)F)c4)ccc23)cc1.

What is the InChIKey of 4-(4-amino-2-fluorophenoxy)-7-methoxy-N-methylquinoline-6-carboxamide;1-[4-(4-amino-2-fluorophenoxy)-7-methoxyquinolin-6-yl]butan-2-one;4-(4-aminophenoxy)-7-methoxy-N-methylquinoline-6-carboxamide;4-[7-[1-(difluoromethyl)pyrazol-4-yl]quinolin-4-yl]oxyaniline;6-(6,7-dimethoxyquinolin-4-yl)oxy-5-fluoropyridin-3-amine;3-fluoro-4-[(6-methoxy-1,7-naphthyridin-4-yl)oxy]aniline?

The InChIKey is FUYHSMUFZPBIST-UHFFFAOYSA-N. The full InChI is InChI=1S/C20H19FN2O3.C19H14F2N4O.C18H16FN3O3.C18H17N3O3.C16H14FN3O3.C15H12FN3O2/c1-3-14(24)8-12-9-15-17(11-20(12)25-2)23-7-6-18(15)26-19-5-4-13(22)10-16(19)21;20-19(21)25-11-13(10-24-25)12-1-6-16-17(9-12)23-8-7-18(16)26-15-4-2-14(22)3-5-15;1-21-18(23)12-8-11-14(9-17(12)24-2)22-6-5-15(11)25-16-4-3-10(20)7-13(16)19;1-20-18(22)14-9-13-15(10-17(14)23-2)21-8-7-16(13)24-12-5-3-11(19)4-6-12;1-21-14-6-10-12(7-15(14)22-2)19-4-3-13(10)23-16-11(17)5-9(18)8-20-16;1-20-15-7-10-12(8-19-15)18-5-4-13(10)21-14-3-2-9(17)6-11(14)16/h4-7,9-11H,3,8,22H2,1-2H3;1-11,19H,22H2;3-9H,20H2,1-2H3,(H,21,23);3-10H,19H2,1-2H3,(H,20,22);3-8H,18H2,1-2H3;2-8H,17H2,1H3.

What are the key properties of 4-(4-amino-2-fluorophenoxy)-7-methoxy-N-methylquinoline-6-carboxamide;1-[4-(4-amino-2-fluorophenoxy)-7-methoxyquinolin-6-yl]butan-2-one;4-(4-aminophenoxy)-7-methoxy-N-methylquinoline-6-carboxamide;4-[7-[1-(difluoromethyl)pyrazol-4-yl]quinolin-4-yl]oxyaniline;6-(6,7-dimethoxyquinolin-4-yl)oxy-5-fluoropyridin-3-amine;3-fluoro-4-[(6-methoxy-1,7-naphthyridin-4-yl)oxy]aniline?

4-(4-amino-2-fluorophenoxy)-7-methoxy-N-methylquinoline-6-carboxamide;1-[4-(4-amino-2-fluorophenoxy)-7-methoxyquinolin-6-yl]butan-2-one;4-(4-aminophenoxy)-7-methoxy-N-methylquinoline-6-carboxamide;4-[7-[1-(difluoromethyl)pyrazol-4-yl]quinolin-4-yl]oxyaniline;6-(6,7-dimethoxyquinolin-4-yl)oxy-5-fluoropyridin-3-amine;3-fluoro-4-[(6-methoxy-1,7-naphthyridin-4-yl)oxy]aniline has a molecular weight of 1972.00 g/mol, XLogP of 21.55, 25 rotatable bonds, 8 hydrogen bond donors, and 31 hydrogen bond acceptors.

Where does this data come from?

All data for 4-(4-amino-2-fluorophenoxy)-7-methoxy-N-methylquinoline-6-carboxamide;1-[4-(4-amino-2-fluorophenoxy)-7-methoxyquinolin-6-yl]butan-2-one;4-(4-aminophenoxy)-7-methoxy-N-methylquinoline-6-carboxamide;4-[7-[1-(difluoromethyl)pyrazol-4-yl]quinolin-4-yl]oxyaniline;6-(6,7-dimethoxyquinolin-4-yl)oxy-5-fluoropyridin-3-amine;3-fluoro-4-[(6-methoxy-1,7-naphthyridin-4-yl)oxy]aniline is sourced from PubChem (CID 167570326), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).