N-[(6-chloro-3-pyridinyl)methyl]-3-(7-methoxyquinolin-4-yl)oxy-2-methylbenzamide;3-(7-chloroquinolin-4-yl)oxy-N-[(2,6-difluoro-4-pyridinyl)methyl]-2-methylbenzamide;N-[(2,5-difluoro-4-pyridinyl)methyl]-3-(7-ethylquinolin-4-yl)oxy-2-methylbenzamide;N-[(2,6-difluoro-4-pyridinyl)methyl]-2-methyl-3-(7-methylquinolin-4-yl)oxybenzamide;N-[(2,6-dimethyl-4-pyridinyl)methyl]-3-(7-methoxyquinolin-4-yl)oxy-2-methylbenzamide;2-methyl-3-(7-methylquinolin-4-yl)oxy-N-[(2,3,6-trifluoro-4-pyridinyl)methyl]benzamide

C146H119Cl2F9N18O14 — CID 167577326

About N-[(6-chloro-3-pyridinyl)methyl]-3-(7-methoxyquinolin-4-yl)oxy-2-methylbenzamide;3-(7-chloroquinolin-4-yl)oxy-N-[(2,6-difluoro-4-pyridinyl)methyl]-2-methylbenzamide;N-[(2,5-difluoro-4-pyridinyl)methyl]-3-(7-ethylquinolin-4-yl)oxy-2-methylbenzamide;N-[(2,6-difluoro-4-pyridinyl)methyl]-2-methyl-3-(7-methylquinolin-4-yl)oxybenzamide;N-[(2,6-dimethyl-4-pyridinyl)methyl]-3-(7-methoxyquinolin-4-yl)oxy-2-methylbenzamide;2-methyl-3-(7-methylquinolin-4-yl)oxy-N-[(2,3,6-trifluoro-4-pyridinyl)methyl]benzamide

N-[(6-chloro-3-pyridinyl)methyl]-3-(7-methoxyquinolin-4-yl)oxy-2-methylbenzamide;3-(7-chloroquinolin-4-yl)oxy-N-[(2,6-difluoro-4-pyridinyl)methyl]-2-methylbenzamide;N-[(2,5-difluoro-4-pyridinyl)methyl]-3-(7-ethylquinolin-4-yl)oxy-2-methylbenzamide;N-[(2,6-difluoro-4-pyridinyl)methyl]-2-methyl-3-(7-methylquinolin-4-yl)oxybenzamide;N-[(2,6-dimethyl-4-pyridinyl)methyl]-3-(7-methoxyquinolin-4-yl)oxy-2-methylbenzamide;2-methyl-3-(7-methylquinolin-4-yl)oxy-N-[(2,3,6-trifluoro-4-pyridinyl)methyl]benzamide (PubChem CID 167577326) has the molecular formula C146H119Cl2F9N18O14 and a molecular weight of 2591.56 g/mol. Its IUPAC name is N-[(6-chloro-3-pyridinyl)methyl]-3-(7-methoxyquinolin-4-yl)oxy-2-methylbenzamide;3-(7-chloroquinolin-4-yl)oxy-N-[(2,6-difluoro-4-pyridinyl)methyl]-2-methylbenzamide;N-[(2,5-difluoro-4-pyridinyl)methyl]-3-(7-ethylquinolin-4-yl)oxy-2-methylbenzamide;N-[(2,6-difluoro-4-pyridinyl)methyl]-2-methyl-3-(7-methylquinolin-4-yl)oxybenzamide;N-[(2,6-dimethyl-4-pyridinyl)methyl]-3-(7-methoxyquinolin-4-yl)oxy-2-methylbenzamide;2-methyl-3-(7-methylquinolin-4-yl)oxy-N-[(2,3,6-trifluoro-4-pyridinyl)methyl]benzamide.

Molecular Properties

• Compound Name: N-[(6-chloro-3-pyridinyl)methyl]-3-(7-methoxyquinolin-4-yl)oxy-2-methylbenzamide;3-(7-chloroquinolin-4-yl)oxy-N-[(2,6-difluoro-4-pyridinyl)methyl]-2-methylbenzamide;N-[(2,5-difluoro-4-pyridinyl)methyl]-3-(7-ethylquinolin-4-yl)oxy-2-methylbenzamide;N-[(2,6-difluoro-4-pyridinyl)methyl]-2-methyl-3-(7-methylquinolin-4-yl)oxybenzamide;N-[(2,6-dimethyl-4-pyridinyl)methyl]-3-(7-methoxyquinolin-4-yl)oxy-2-methylbenzamide;2-methyl-3-(7-methylquinolin-4-yl)oxy-N-[(2,3,6-trifluoro-4-pyridinyl)methyl]benzamide
• PubChem CID: 167577326
• Molecular Formula: C146H119Cl2F9N18O14
• Molecular Weight: 2591.56 g/mol
• Exact Mass: 2588.84
• IUPAC Name: N-[(6-chloro-3-pyridinyl)methyl]-3-(7-methoxyquinolin-4-yl)oxy-2-methylbenzamide;3-(7-chloroquinolin-4-yl)oxy-N-[(2,6-difluoro-4-pyridinyl)methyl]-2-methylbenzamide;N-[(2,5-difluoro-4-pyridinyl)methyl]-3-(7-ethylquinolin-4-yl)oxy-2-methylbenzamide;N-[(2,6-difluoro-4-pyridinyl)methyl]-2-methyl-3-(7-methylquinolin-4-yl)oxybenzamide;N-[(2,6-dimethyl-4-pyridinyl)methyl]-3-(7-methoxyquinolin-4-yl)oxy-2-methylbenzamide;2-methyl-3-(7-methylquinolin-4-yl)oxy-N-[(2,3,6-trifluoro-4-pyridinyl)methyl]benzamide
• SMILES: CCc1ccc2c(Oc3cccc(C(=O)NCc4cc(F)ncc4F)c3C)ccnc2c1.COc1ccc2c(Oc3cccc(C(=O)NCc4cc(C)nc(C)c4)c3C)ccnc2c1.COc1ccc2c(Oc3cccc(C(=O)NCc4ccc(Cl)nc4)c3C)ccnc2c1.Cc1c(Oc2ccnc3cc(Cl)ccc23)cccc1C(=O)NCc1cc(F)nc(F)c1.Cc1ccc2c(Oc3cccc(C(=O)NCc4cc(F)nc(F)c4)c3C)ccnc2c1.Cc1ccc2c(Oc3cccc(C(=O)NCc4cc(F)nc(F)c4F)c3C)ccnc2c1
• InChI: InChI=1S/C26H25N3O3.C25H21F2N3O2.C24H20ClN3O3.C24H18F3N3O2.C24H19F2N3O2.C23H16ClF2N3O2/c1-16-12-19(13-17(2)29-16)15-28-26(30)21-6-5-7-24(18(21)3)32-25-10-11-27-23-14-20(31-4)8-9-22(23)25;1-3-16-7-8-19-21(11-16)28-10-9-23(19)32-22-6-4-5-18(15(22)2)25(31)30-13-17-12-24(27)29-14-20(17)26;1-15-18(24(29)28-14-16-6-9-23(25)27-13-16)4-3-5-21(15)31-22-10-11-26-20-12-17(30-2)7-8-19(20)22;1-13-6-7-17-18(10-13)28-9-8-20(17)32-19-5-3-4-16(14(19)2)24(31)29-12-15-11-21(25)30-23(27)22(15)26;1-14-6-7-18-19(10-14)27-9-8-21(18)31-20-5-3-4-17(15(20)2)24(30)28-13-16-11-22(25)29-23(26)12-16;1-13-16(23(30)28-12-14-9-21(25)29-22(26)10-14)3-2-4-19(13)31-20-7-8-27-18-11-15(24)5-6-17(18)20/h5-14H,15H2,1-4H3,(H,28,30);4-12,14H,3,13H2,1-2H3,(H,30,31);3-13H,14H2,1-2H3,(H,28,29);3-11H,12H2,1-2H3,(H,29,31);3-12H,13H2,1-2H3,(H,28,30);2-11H,12H2,1H3,(H,28,30)
• InChIKey: GSFATULUAAZXCF-UHFFFAOYSA-N
• XLogP: 32.34
• TPSA: 403.12 Ų
• H-Bond Donors: 6
• H-Bond Acceptors: 26
• Rotatable Bonds: 33
• Heavy Atoms: 189
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2591.56
LogP ≤ 5	32.34
H-Bond Donors ≤ 5	6
H-Bond Acceptors ≤ 10	26

Computed Properties (RDKit)

• Structural Alerts: {'alert_name': '2-halo_pyridine', 'substructure': 'N/A'}

Frequently Asked Questions

What is the IUPAC name of N-[(6-chloro-3-pyridinyl)methyl]-3-(7-methoxyquinolin-4-yl)oxy-2-methylbenzamide;3-(7-chloroquinolin-4-yl)oxy-N-[(2,6-difluoro-4-pyridinyl)methyl]-2-methylbenzamide;N-[(2,5-difluoro-4-pyridinyl)methyl]-3-(7-ethylquinolin-4-yl)oxy-2-methylbenzamide;N-[(2,6-difluoro-4-pyridinyl)methyl]-2-methyl-3-(7-methylquinolin-4-yl)oxybenzamide;N-[(2,6-dimethyl-4-pyridinyl)methyl]-3-(7-methoxyquinolin-4-yl)oxy-2-methylbenzamide;2-methyl-3-(7-methylquinolin-4-yl)oxy-N-[(2,3,6-trifluoro-4-pyridinyl)methyl]benzamide?

The IUPAC name of N-[(6-chloro-3-pyridinyl)methyl]-3-(7-methoxyquinolin-4-yl)oxy-2-methylbenzamide;3-(7-chloroquinolin-4-yl)oxy-N-[(2,6-difluoro-4-pyridinyl)methyl]-2-methylbenzamide;N-[(2,5-difluoro-4-pyridinyl)methyl]-3-(7-ethylquinolin-4-yl)oxy-2-methylbenzamide;N-[(2,6-difluoro-4-pyridinyl)methyl]-2-methyl-3-(7-methylquinolin-4-yl)oxybenzamide;N-[(2,6-dimethyl-4-pyridinyl)methyl]-3-(7-methoxyquinolin-4-yl)oxy-2-methylbenzamide;2-methyl-3-(7-methylquinolin-4-yl)oxy-N-[(2,3,6-trifluoro-4-pyridinyl)methyl]benzamide (CID 167577326) is N-[(6-chloro-3-pyridinyl)methyl]-3-(7-methoxyquinolin-4-yl)oxy-2-methylbenzamide;3-(7-chloroquinolin-4-yl)oxy-N-[(2,6-difluoro-4-pyridinyl)methyl]-2-methylbenzamide;N-[(2,5-difluoro-4-pyridinyl)methyl]-3-(7-ethylquinolin-4-yl)oxy-2-methylbenzamide;N-[(2,6-difluoro-4-pyridinyl)methyl]-2-methyl-3-(7-methylquinolin-4-yl)oxybenzamide;N-[(2,6-dimethyl-4-pyridinyl)methyl]-3-(7-methoxyquinolin-4-yl)oxy-2-methylbenzamide;2-methyl-3-(7-methylquinolin-4-yl)oxy-N-[(2,3,6-trifluoro-4-pyridinyl)methyl]benzamide.

What is the SMILES notation for N-[(6-chloro-3-pyridinyl)methyl]-3-(7-methoxyquinolin-4-yl)oxy-2-methylbenzamide;3-(7-chloroquinolin-4-yl)oxy-N-[(2,6-difluoro-4-pyridinyl)methyl]-2-methylbenzamide;N-[(2,5-difluoro-4-pyridinyl)methyl]-3-(7-ethylquinolin-4-yl)oxy-2-methylbenzamide;N-[(2,6-difluoro-4-pyridinyl)methyl]-2-methyl-3-(7-methylquinolin-4-yl)oxybenzamide;N-[(2,6-dimethyl-4-pyridinyl)methyl]-3-(7-methoxyquinolin-4-yl)oxy-2-methylbenzamide;2-methyl-3-(7-methylquinolin-4-yl)oxy-N-[(2,3,6-trifluoro-4-pyridinyl)methyl]benzamide?

The canonical SMILES for N-[(6-chloro-3-pyridinyl)methyl]-3-(7-methoxyquinolin-4-yl)oxy-2-methylbenzamide;3-(7-chloroquinolin-4-yl)oxy-N-[(2,6-difluoro-4-pyridinyl)methyl]-2-methylbenzamide;N-[(2,5-difluoro-4-pyridinyl)methyl]-3-(7-ethylquinolin-4-yl)oxy-2-methylbenzamide;N-[(2,6-difluoro-4-pyridinyl)methyl]-2-methyl-3-(7-methylquinolin-4-yl)oxybenzamide;N-[(2,6-dimethyl-4-pyridinyl)methyl]-3-(7-methoxyquinolin-4-yl)oxy-2-methylbenzamide;2-methyl-3-(7-methylquinolin-4-yl)oxy-N-[(2,3,6-trifluoro-4-pyridinyl)methyl]benzamide is CCc1ccc2c(Oc3cccc(C(=O)NCc4cc(F)ncc4F)c3C)ccnc2c1.COc1ccc2c(Oc3cccc(C(=O)NCc4cc(C)nc(C)c4)c3C)ccnc2c1.COc1ccc2c(Oc3cccc(C(=O)NCc4ccc(Cl)nc4)c3C)ccnc2c1.Cc1c(Oc2ccnc3cc(Cl)ccc23)cccc1C(=O)NCc1cc(F)nc(F)c1.Cc1ccc2c(Oc3cccc(C(=O)NCc4cc(F)nc(F)c4)c3C)ccnc2c1.Cc1ccc2c(Oc3cccc(C(=O)NCc4cc(F)nc(F)c4F)c3C)ccnc2c1.

What is the InChIKey of N-[(6-chloro-3-pyridinyl)methyl]-3-(7-methoxyquinolin-4-yl)oxy-2-methylbenzamide;3-(7-chloroquinolin-4-yl)oxy-N-[(2,6-difluoro-4-pyridinyl)methyl]-2-methylbenzamide;N-[(2,5-difluoro-4-pyridinyl)methyl]-3-(7-ethylquinolin-4-yl)oxy-2-methylbenzamide;N-[(2,6-difluoro-4-pyridinyl)methyl]-2-methyl-3-(7-methylquinolin-4-yl)oxybenzamide;N-[(2,6-dimethyl-4-pyridinyl)methyl]-3-(7-methoxyquinolin-4-yl)oxy-2-methylbenzamide;2-methyl-3-(7-methylquinolin-4-yl)oxy-N-[(2,3,6-trifluoro-4-pyridinyl)methyl]benzamide?

The InChIKey is GSFATULUAAZXCF-UHFFFAOYSA-N. The full InChI is InChI=1S/C26H25N3O3.C25H21F2N3O2.C24H20ClN3O3.C24H18F3N3O2.C24H19F2N3O2.C23H16ClF2N3O2/c1-16-12-19(13-17(2)29-16)15-28-26(30)21-6-5-7-24(18(21)3)32-25-10-11-27-23-14-20(31-4)8-9-22(23)25;1-3-16-7-8-19-21(11-16)28-10-9-23(19)32-22-6-4-5-18(15(22)2)25(31)30-13-17-12-24(27)29-14-20(17)26;1-15-18(24(29)28-14-16-6-9-23(25)27-13-16)4-3-5-21(15)31-22-10-11-26-20-12-17(30-2)7-8-19(20)22;1-13-6-7-17-18(10-13)28-9-8-20(17)32-19-5-3-4-16(14(19)2)24(31)29-12-15-11-21(25)30-23(27)22(15)26;1-14-6-7-18-19(10-14)27-9-8-21(18)31-20-5-3-4-17(15(20)2)24(30)28-13-16-11-22(25)29-23(26)12-16;1-13-16(23(30)28-12-14-9-21(25)29-22(26)10-14)3-2-4-19(13)31-20-7-8-27-18-11-15(24)5-6-17(18)20/h5-14H,15H2,1-4H3,(H,28,30);4-12,14H,3,13H2,1-2H3,(H,30,31);3-13H,14H2,1-2H3,(H,28,29);3-11H,12H2,1-2H3,(H,29,31);3-12H,13H2,1-2H3,(H,28,30);2-11H,12H2,1H3,(H,28,30).

What are the key properties of N-[(6-chloro-3-pyridinyl)methyl]-3-(7-methoxyquinolin-4-yl)oxy-2-methylbenzamide;3-(7-chloroquinolin-4-yl)oxy-N-[(2,6-difluoro-4-pyridinyl)methyl]-2-methylbenzamide;N-[(2,5-difluoro-4-pyridinyl)methyl]-3-(7-ethylquinolin-4-yl)oxy-2-methylbenzamide;N-[(2,6-difluoro-4-pyridinyl)methyl]-2-methyl-3-(7-methylquinolin-4-yl)oxybenzamide;N-[(2,6-dimethyl-4-pyridinyl)methyl]-3-(7-methoxyquinolin-4-yl)oxy-2-methylbenzamide;2-methyl-3-(7-methylquinolin-4-yl)oxy-N-[(2,3,6-trifluoro-4-pyridinyl)methyl]benzamide?

N-[(6-chloro-3-pyridinyl)methyl]-3-(7-methoxyquinolin-4-yl)oxy-2-methylbenzamide;3-(7-chloroquinolin-4-yl)oxy-N-[(2,6-difluoro-4-pyridinyl)methyl]-2-methylbenzamide;N-[(2,5-difluoro-4-pyridinyl)methyl]-3-(7-ethylquinolin-4-yl)oxy-2-methylbenzamide;N-[(2,6-difluoro-4-pyridinyl)methyl]-2-methyl-3-(7-methylquinolin-4-yl)oxybenzamide;N-[(2,6-dimethyl-4-pyridinyl)methyl]-3-(7-methoxyquinolin-4-yl)oxy-2-methylbenzamide;2-methyl-3-(7-methylquinolin-4-yl)oxy-N-[(2,3,6-trifluoro-4-pyridinyl)methyl]benzamide has a molecular weight of 2591.56 g/mol, XLogP of 32.34, 33 rotatable bonds, 6 hydrogen bond donors, and 26 hydrogen bond acceptors.

Where does this data come from?

All data for N-[(6-chloro-3-pyridinyl)methyl]-3-(7-methoxyquinolin-4-yl)oxy-2-methylbenzamide;3-(7-chloroquinolin-4-yl)oxy-N-[(2,6-difluoro-4-pyridinyl)methyl]-2-methylbenzamide;N-[(2,5-difluoro-4-pyridinyl)methyl]-3-(7-ethylquinolin-4-yl)oxy-2-methylbenzamide;N-[(2,6-difluoro-4-pyridinyl)methyl]-2-methyl-3-(7-methylquinolin-4-yl)oxybenzamide;N-[(2,6-dimethyl-4-pyridinyl)methyl]-3-(7-methoxyquinolin-4-yl)oxy-2-methylbenzamide;2-methyl-3-(7-methylquinolin-4-yl)oxy-N-[(2,3,6-trifluoro-4-pyridinyl)methyl]benzamide is sourced from PubChem (CID 167577326), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).