2-[(6-fluoro-5-imidazo[1,2-a]pyrazin-3-yl-2-pyridinyl)oxy]-N-[4-methyl-3-(trifluoromethyl)phenyl]acetamide;2-[(6-fluoro-5-imidazo[1,2-a]pyrazin-3-yl-2-pyridinyl)oxy]-N-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]acetamide;2-[(5-imidazo[1,2-a]pyridin-3-yl-2-pyridinyl)oxy]-N-[5-methyl-4-(trifluoromethyl)-2-pyridinyl]acetamide;1-[4-methyl-3-(trifluoromethyl)phenyl]-3-[4-[6-[4-(morpholine-4-carbonyl)phenyl]imidazo[1,2-a]pyridin-3-yl]phenoxy]propan-2-one;1-[4-methyl-3-(trifluoromethyl)phenyl]-3-[4-[6-[4-(piperazine-1-carbonyl)phenyl]imidazo[1,2-a]pyridin-3-yl]phenoxy]propan-2-one

C130H105F17N24O13 — CID 167584050

About 2-[(6-fluoro-5-imidazo[1,2-a]pyrazin-3-yl-2-pyridinyl)oxy]-N-[4-methyl-3-(trifluoromethyl)phenyl]acetamide;2-[(6-fluoro-5-imidazo[1,2-a]pyrazin-3-yl-2-pyridinyl)oxy]-N-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]acetamide;2-[(5-imidazo[1,2-a]pyridin-3-yl-2-pyridinyl)oxy]-N-[5-methyl-4-(trifluoromethyl)-2-pyridinyl]acetamide;1-[4-methyl-3-(trifluoromethyl)phenyl]-3-[4-[6-[4-(morpholine-4-carbonyl)phenyl]imidazo[1,2-a]pyridin-3-yl]phenoxy]propan-2-one;1-[4-methyl-3-(trifluoromethyl)phenyl]-3-[4-[6-[4-(piperazine-1-carbonyl)phenyl]imidazo[1,2-a]pyridin-3-yl]phenoxy]propan-2-one

2-[(6-fluoro-5-imidazo[1,2-a]pyrazin-3-yl-2-pyridinyl)oxy]-N-[4-methyl-3-(trifluoromethyl)phenyl]acetamide;2-[(6-fluoro-5-imidazo[1,2-a]pyrazin-3-yl-2-pyridinyl)oxy]-N-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]acetamide;2-[(5-imidazo[1,2-a]pyridin-3-yl-2-pyridinyl)oxy]-N-[5-methyl-4-(trifluoromethyl)-2-pyridinyl]acetamide;1-[4-methyl-3-(trifluoromethyl)phenyl]-3-[4-[6-[4-(morpholine-4-carbonyl)phenyl]imidazo[1,2-a]pyridin-3-yl]phenoxy]propan-2-one;1-[4-methyl-3-(trifluoromethyl)phenyl]-3-[4-[6-[4-(piperazine-1-carbonyl)phenyl]imidazo[1,2-a]pyridin-3-yl]phenoxy]propan-2-one (PubChem CID 167584050) has the molecular formula C130H105F17N24O13 and a molecular weight of 2534.39 g/mol. Its IUPAC name is 2-[(6-fluoro-5-imidazo[1,2-a]pyrazin-3-yl-2-pyridinyl)oxy]-N-[4-methyl-3-(trifluoromethyl)phenyl]acetamide;2-[(6-fluoro-5-imidazo[1,2-a]pyrazin-3-yl-2-pyridinyl)oxy]-N-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]acetamide;2-[(5-imidazo[1,2-a]pyridin-3-yl-2-pyridinyl)oxy]-N-[5-methyl-4-(trifluoromethyl)-2-pyridinyl]acetamide;1-[4-methyl-3-(trifluoromethyl)phenyl]-3-[4-[6-[4-(morpholine-4-carbonyl)phenyl]imidazo[1,2-a]pyridin-3-yl]phenoxy]propan-2-one;1-[4-methyl-3-(trifluoromethyl)phenyl]-3-[4-[6-[4-(piperazine-1-carbonyl)phenyl]imidazo[1,2-a]pyridin-3-yl]phenoxy]propan-2-one.

Molecular Properties

• Compound Name: 2-[(6-fluoro-5-imidazo[1,2-a]pyrazin-3-yl-2-pyridinyl)oxy]-N-[4-methyl-3-(trifluoromethyl)phenyl]acetamide;2-[(6-fluoro-5-imidazo[1,2-a]pyrazin-3-yl-2-pyridinyl)oxy]-N-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]acetamide;2-[(5-imidazo[1,2-a]pyridin-3-yl-2-pyridinyl)oxy]-N-[5-methyl-4-(trifluoromethyl)-2-pyridinyl]acetamide;1-[4-methyl-3-(trifluoromethyl)phenyl]-3-[4-[6-[4-(morpholine-4-carbonyl)phenyl]imidazo[1,2-a]pyridin-3-yl]phenoxy]propan-2-one;1-[4-methyl-3-(trifluoromethyl)phenyl]-3-[4-[6-[4-(piperazine-1-carbonyl)phenyl]imidazo[1,2-a]pyridin-3-yl]phenoxy]propan-2-one
• PubChem CID: 167584050
• Molecular Formula: C130H105F17N24O13
• Molecular Weight: 2534.39 g/mol
• Exact Mass: 2532.80
• IUPAC Name: 2-[(6-fluoro-5-imidazo[1,2-a]pyrazin-3-yl-2-pyridinyl)oxy]-N-[4-methyl-3-(trifluoromethyl)phenyl]acetamide;2-[(6-fluoro-5-imidazo[1,2-a]pyrazin-3-yl-2-pyridinyl)oxy]-N-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]acetamide;2-[(5-imidazo[1,2-a]pyridin-3-yl-2-pyridinyl)oxy]-N-[5-methyl-4-(trifluoromethyl)-2-pyridinyl]acetamide;1-[4-methyl-3-(trifluoromethyl)phenyl]-3-[4-[6-[4-(morpholine-4-carbonyl)phenyl]imidazo[1,2-a]pyridin-3-yl]phenoxy]propan-2-one;1-[4-methyl-3-(trifluoromethyl)phenyl]-3-[4-[6-[4-(piperazine-1-carbonyl)phenyl]imidazo[1,2-a]pyridin-3-yl]phenoxy]propan-2-one
• SMILES: Cc1ccc(CC(=O)COc2ccc(-c3cnc4ccc(-c5ccc(C(=O)N6CCNCC6)cc5)cn34)cc2)cc1C(F)(F)F.Cc1ccc(CC(=O)COc2ccc(-c3cnc4ccc(-c5ccc(C(=O)N6CCOCC6)cc5)cn34)cc2)cc1C(F)(F)F.Cc1ccc(NC(=O)COc2ccc(-c3cnc4cnccn34)c(F)n2)cc1C(F)(F)F.Cc1cnc(NC(=O)COc2ccc(-c3cnc4ccccn34)cn2)cc1C(F)(F)F.Cn1nc(NC(=O)COc2ccc(-c3cnc4cnccn34)c(F)n2)cc1C(F)(F)F
• InChI: InChI=1S/C35H31F3N4O3.C35H30F3N3O4.C21H15F4N5O2.C21H16F3N5O2.C18H13F4N7O2/c1-23-2-3-24(19-31(23)35(36,37)38)18-29(43)22-45-30-11-8-26(9-12-30)32-20-40-33-13-10-28(21-42(32)33)25-4-6-27(7-5-25)34(44)41-16-14-39-15-17-41;1-23-2-3-24(19-31(23)35(36,37)38)18-29(42)22-45-30-11-8-26(9-12-30)32-20-39-33-13-10-28(21-41(32)33)25-4-6-27(7-5-25)34(43)40-14-16-44-17-15-40;1-12-2-3-13(8-15(12)21(23,24)25)28-18(31)11-32-19-5-4-14(20(22)29-19)16-9-27-17-10-26-6-7-30(16)17;1-13-9-25-17(8-15(13)21(22,23)24)28-19(30)12-31-20-6-5-14(10-27-20)16-11-26-18-4-2-3-7-29(16)18;1-28-12(18(20,21)22)6-13(27-28)25-15(30)9-31-16-3-2-10(17(19)26-16)11-7-24-14-8-23-4-5-29(11)14/h2-13,19-21,39H,14-18,22H2,1H3;2-13,19-21H,14-18,22H2,1H3;2-10H,11H2,1H3,(H,28,31);2-11H,12H2,1H3,(H,25,28,30);2-8H,9H2,1H3,(H,25,27,30)
• InChIKey: HNZWRIRTZMZEKL-UHFFFAOYSA-N
• XLogP: 24.00
• TPSA: 411.13 Ų
• H-Bond Donors: 4
• H-Bond Acceptors: 32
• Rotatable Bonds: 31
• Heavy Atoms: 184
• Complexity: —

Lipinski Rule of Five

3 violations

Rule	Value
MW ≤ 500	2534.39
LogP ≤ 5	24.00
H-Bond Donors ≤ 5	4
H-Bond Acceptors ≤ 10	32

Computed Properties (RDKit)

• Structural Alerts: {'alert_name': '2-halo_pyridine', 'substructure': 'N/A'}

Frequently Asked Questions

What is the IUPAC name of 2-[(6-fluoro-5-imidazo[1,2-a]pyrazin-3-yl-2-pyridinyl)oxy]-N-[4-methyl-3-(trifluoromethyl)phenyl]acetamide;2-[(6-fluoro-5-imidazo[1,2-a]pyrazin-3-yl-2-pyridinyl)oxy]-N-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]acetamide;2-[(5-imidazo[1,2-a]pyridin-3-yl-2-pyridinyl)oxy]-N-[5-methyl-4-(trifluoromethyl)-2-pyridinyl]acetamide;1-[4-methyl-3-(trifluoromethyl)phenyl]-3-[4-[6-[4-(morpholine-4-carbonyl)phenyl]imidazo[1,2-a]pyridin-3-yl]phenoxy]propan-2-one;1-[4-methyl-3-(trifluoromethyl)phenyl]-3-[4-[6-[4-(piperazine-1-carbonyl)phenyl]imidazo[1,2-a]pyridin-3-yl]phenoxy]propan-2-one?

The IUPAC name of 2-[(6-fluoro-5-imidazo[1,2-a]pyrazin-3-yl-2-pyridinyl)oxy]-N-[4-methyl-3-(trifluoromethyl)phenyl]acetamide;2-[(6-fluoro-5-imidazo[1,2-a]pyrazin-3-yl-2-pyridinyl)oxy]-N-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]acetamide;2-[(5-imidazo[1,2-a]pyridin-3-yl-2-pyridinyl)oxy]-N-[5-methyl-4-(trifluoromethyl)-2-pyridinyl]acetamide;1-[4-methyl-3-(trifluoromethyl)phenyl]-3-[4-[6-[4-(morpholine-4-carbonyl)phenyl]imidazo[1,2-a]pyridin-3-yl]phenoxy]propan-2-one;1-[4-methyl-3-(trifluoromethyl)phenyl]-3-[4-[6-[4-(piperazine-1-carbonyl)phenyl]imidazo[1,2-a]pyridin-3-yl]phenoxy]propan-2-one (CID 167584050) is 2-[(6-fluoro-5-imidazo[1,2-a]pyrazin-3-yl-2-pyridinyl)oxy]-N-[4-methyl-3-(trifluoromethyl)phenyl]acetamide;2-[(6-fluoro-5-imidazo[1,2-a]pyrazin-3-yl-2-pyridinyl)oxy]-N-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]acetamide;2-[(5-imidazo[1,2-a]pyridin-3-yl-2-pyridinyl)oxy]-N-[5-methyl-4-(trifluoromethyl)-2-pyridinyl]acetamide;1-[4-methyl-3-(trifluoromethyl)phenyl]-3-[4-[6-[4-(morpholine-4-carbonyl)phenyl]imidazo[1,2-a]pyridin-3-yl]phenoxy]propan-2-one;1-[4-methyl-3-(trifluoromethyl)phenyl]-3-[4-[6-[4-(piperazine-1-carbonyl)phenyl]imidazo[1,2-a]pyridin-3-yl]phenoxy]propan-2-one.

What is the SMILES notation for 2-[(6-fluoro-5-imidazo[1,2-a]pyrazin-3-yl-2-pyridinyl)oxy]-N-[4-methyl-3-(trifluoromethyl)phenyl]acetamide;2-[(6-fluoro-5-imidazo[1,2-a]pyrazin-3-yl-2-pyridinyl)oxy]-N-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]acetamide;2-[(5-imidazo[1,2-a]pyridin-3-yl-2-pyridinyl)oxy]-N-[5-methyl-4-(trifluoromethyl)-2-pyridinyl]acetamide;1-[4-methyl-3-(trifluoromethyl)phenyl]-3-[4-[6-[4-(morpholine-4-carbonyl)phenyl]imidazo[1,2-a]pyridin-3-yl]phenoxy]propan-2-one;1-[4-methyl-3-(trifluoromethyl)phenyl]-3-[4-[6-[4-(piperazine-1-carbonyl)phenyl]imidazo[1,2-a]pyridin-3-yl]phenoxy]propan-2-one?

The canonical SMILES for 2-[(6-fluoro-5-imidazo[1,2-a]pyrazin-3-yl-2-pyridinyl)oxy]-N-[4-methyl-3-(trifluoromethyl)phenyl]acetamide;2-[(6-fluoro-5-imidazo[1,2-a]pyrazin-3-yl-2-pyridinyl)oxy]-N-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]acetamide;2-[(5-imidazo[1,2-a]pyridin-3-yl-2-pyridinyl)oxy]-N-[5-methyl-4-(trifluoromethyl)-2-pyridinyl]acetamide;1-[4-methyl-3-(trifluoromethyl)phenyl]-3-[4-[6-[4-(morpholine-4-carbonyl)phenyl]imidazo[1,2-a]pyridin-3-yl]phenoxy]propan-2-one;1-[4-methyl-3-(trifluoromethyl)phenyl]-3-[4-[6-[4-(piperazine-1-carbonyl)phenyl]imidazo[1,2-a]pyridin-3-yl]phenoxy]propan-2-one is Cc1ccc(CC(=O)COc2ccc(-c3cnc4ccc(-c5ccc(C(=O)N6CCNCC6)cc5)cn34)cc2)cc1C(F)(F)F.Cc1ccc(CC(=O)COc2ccc(-c3cnc4ccc(-c5ccc(C(=O)N6CCOCC6)cc5)cn34)cc2)cc1C(F)(F)F.Cc1ccc(NC(=O)COc2ccc(-c3cnc4cnccn34)c(F)n2)cc1C(F)(F)F.Cc1cnc(NC(=O)COc2ccc(-c3cnc4ccccn34)cn2)cc1C(F)(F)F.Cn1nc(NC(=O)COc2ccc(-c3cnc4cnccn34)c(F)n2)cc1C(F)(F)F.

What is the InChIKey of 2-[(6-fluoro-5-imidazo[1,2-a]pyrazin-3-yl-2-pyridinyl)oxy]-N-[4-methyl-3-(trifluoromethyl)phenyl]acetamide;2-[(6-fluoro-5-imidazo[1,2-a]pyrazin-3-yl-2-pyridinyl)oxy]-N-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]acetamide;2-[(5-imidazo[1,2-a]pyridin-3-yl-2-pyridinyl)oxy]-N-[5-methyl-4-(trifluoromethyl)-2-pyridinyl]acetamide;1-[4-methyl-3-(trifluoromethyl)phenyl]-3-[4-[6-[4-(morpholine-4-carbonyl)phenyl]imidazo[1,2-a]pyridin-3-yl]phenoxy]propan-2-one;1-[4-methyl-3-(trifluoromethyl)phenyl]-3-[4-[6-[4-(piperazine-1-carbonyl)phenyl]imidazo[1,2-a]pyridin-3-yl]phenoxy]propan-2-one?

The InChIKey is HNZWRIRTZMZEKL-UHFFFAOYSA-N. The full InChI is InChI=1S/C35H31F3N4O3.C35H30F3N3O4.C21H15F4N5O2.C21H16F3N5O2.C18H13F4N7O2/c1-23-2-3-24(19-31(23)35(36,37)38)18-29(43)22-45-30-11-8-26(9-12-30)32-20-40-33-13-10-28(21-42(32)33)25-4-6-27(7-5-25)34(44)41-16-14-39-15-17-41;1-23-2-3-24(19-31(23)35(36,37)38)18-29(42)22-45-30-11-8-26(9-12-30)32-20-39-33-13-10-28(21-41(32)33)25-4-6-27(7-5-25)34(43)40-14-16-44-17-15-40;1-12-2-3-13(8-15(12)21(23,24)25)28-18(31)11-32-19-5-4-14(20(22)29-19)16-9-27-17-10-26-6-7-30(16)17;1-13-9-25-17(8-15(13)21(22,23)24)28-19(30)12-31-20-6-5-14(10-27-20)16-11-26-18-4-2-3-7-29(16)18;1-28-12(18(20,21)22)6-13(27-28)25-15(30)9-31-16-3-2-10(17(19)26-16)11-7-24-14-8-23-4-5-29(11)14/h2-13,19-21,39H,14-18,22H2,1H3;2-13,19-21H,14-18,22H2,1H3;2-10H,11H2,1H3,(H,28,31);2-11H,12H2,1H3,(H,25,28,30);2-8H,9H2,1H3,(H,25,27,30).

What are the key properties of 2-[(6-fluoro-5-imidazo[1,2-a]pyrazin-3-yl-2-pyridinyl)oxy]-N-[4-methyl-3-(trifluoromethyl)phenyl]acetamide;2-[(6-fluoro-5-imidazo[1,2-a]pyrazin-3-yl-2-pyridinyl)oxy]-N-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]acetamide;2-[(5-imidazo[1,2-a]pyridin-3-yl-2-pyridinyl)oxy]-N-[5-methyl-4-(trifluoromethyl)-2-pyridinyl]acetamide;1-[4-methyl-3-(trifluoromethyl)phenyl]-3-[4-[6-[4-(morpholine-4-carbonyl)phenyl]imidazo[1,2-a]pyridin-3-yl]phenoxy]propan-2-one;1-[4-methyl-3-(trifluoromethyl)phenyl]-3-[4-[6-[4-(piperazine-1-carbonyl)phenyl]imidazo[1,2-a]pyridin-3-yl]phenoxy]propan-2-one?

2-[(6-fluoro-5-imidazo[1,2-a]pyrazin-3-yl-2-pyridinyl)oxy]-N-[4-methyl-3-(trifluoromethyl)phenyl]acetamide;2-[(6-fluoro-5-imidazo[1,2-a]pyrazin-3-yl-2-pyridinyl)oxy]-N-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]acetamide;2-[(5-imidazo[1,2-a]pyridin-3-yl-2-pyridinyl)oxy]-N-[5-methyl-4-(trifluoromethyl)-2-pyridinyl]acetamide;1-[4-methyl-3-(trifluoromethyl)phenyl]-3-[4-[6-[4-(morpholine-4-carbonyl)phenyl]imidazo[1,2-a]pyridin-3-yl]phenoxy]propan-2-one;1-[4-methyl-3-(trifluoromethyl)phenyl]-3-[4-[6-[4-(piperazine-1-carbonyl)phenyl]imidazo[1,2-a]pyridin-3-yl]phenoxy]propan-2-one has a molecular weight of 2534.39 g/mol, XLogP of 24.00, 31 rotatable bonds, 4 hydrogen bond donors, and 32 hydrogen bond acceptors.

Where does this data come from?

All data for 2-[(6-fluoro-5-imidazo[1,2-a]pyrazin-3-yl-2-pyridinyl)oxy]-N-[4-methyl-3-(trifluoromethyl)phenyl]acetamide;2-[(6-fluoro-5-imidazo[1,2-a]pyrazin-3-yl-2-pyridinyl)oxy]-N-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]acetamide;2-[(5-imidazo[1,2-a]pyridin-3-yl-2-pyridinyl)oxy]-N-[5-methyl-4-(trifluoromethyl)-2-pyridinyl]acetamide;1-[4-methyl-3-(trifluoromethyl)phenyl]-3-[4-[6-[4-(morpholine-4-carbonyl)phenyl]imidazo[1,2-a]pyridin-3-yl]phenoxy]propan-2-one;1-[4-methyl-3-(trifluoromethyl)phenyl]-3-[4-[6-[4-(piperazine-1-carbonyl)phenyl]imidazo[1,2-a]pyridin-3-yl]phenoxy]propan-2-one is sourced from PubChem (CID 167584050), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).