7-amino-N-[(6S)-2-[(5R)-5-amino-2-oxa-7-azaspiro[3.4]octan-7-yl]-5,6,7,8-tetrahydroquinolin-6-yl]-3-methylthieno[2,3-b]pyrazine-6-carboxamide;7-amino-N-[(6S)-2-[(5S)-5-amino-2-oxa-7-azaspiro[3.4]octan-7-yl]-5,6,7,8-tetrahydroquinolin-6-yl]-3-methylthieno[2,3-b]pyrazine-6-carboxamide;3-amino-N-[(6S)-2-[(3S,4R)-3-amino-4-(trifluoromethyl)pyrrolidin-1-yl]-5,6,7,8-tetrahydroquinolin-6-yl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-N-[(6S)-2-[(3R,4S)-3-amino-4-(trifluoromethyl)pyrrolidin-1-yl]-5,6,7,8-tetrahydroquinolin-6-yl]-6-methylthieno[2,3-b]pyridine-2-carboxamide

C92H104F6N26O6S4 — CID 167603441

About 7-amino-N-[(6S)-2-[(5R)-5-amino-2-oxa-7-azaspiro[3.4]octan-7-yl]-5,6,7,8-tetrahydroquinolin-6-yl]-3-methylthieno[2,3-b]pyrazine-6-carboxamide;7-amino-N-[(6S)-2-[(5S)-5-amino-2-oxa-7-azaspiro[3.4]octan-7-yl]-5,6,7,8-tetrahydroquinolin-6-yl]-3-methylthieno[2,3-b]pyrazine-6-carboxamide;3-amino-N-[(6S)-2-[(3S,4R)-3-amino-4-(trifluoromethyl)pyrrolidin-1-yl]-5,6,7,8-tetrahydroquinolin-6-yl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-N-[(6S)-2-[(3R,4S)-3-amino-4-(trifluoromethyl)pyrrolidin-1-yl]-5,6,7,8-tetrahydroquinolin-6-yl]-6-methylthieno[2,3-b]pyridine-2-carboxamide

7-amino-N-[(6S)-2-[(5R)-5-amino-2-oxa-7-azaspiro[3.4]octan-7-yl]-5,6,7,8-tetrahydroquinolin-6-yl]-3-methylthieno[2,3-b]pyrazine-6-carboxamide;7-amino-N-[(6S)-2-[(5S)-5-amino-2-oxa-7-azaspiro[3.4]octan-7-yl]-5,6,7,8-tetrahydroquinolin-6-yl]-3-methylthieno[2,3-b]pyrazine-6-carboxamide;3-amino-N-[(6S)-2-[(3S,4R)-3-amino-4-(trifluoromethyl)pyrrolidin-1-yl]-5,6,7,8-tetrahydroquinolin-6-yl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-N-[(6S)-2-[(3R,4S)-3-amino-4-(trifluoromethyl)pyrrolidin-1-yl]-5,6,7,8-tetrahydroquinolin-6-yl]-6-methylthieno[2,3-b]pyridine-2-carboxamide (PubChem CID 167603441) has the molecular formula C92H104F6N26O6S4 and a molecular weight of 1912.28 g/mol. Its IUPAC name is 7-amino-N-[(6S)-2-[(5R)-5-amino-2-oxa-7-azaspiro[3.4]octan-7-yl]-5,6,7,8-tetrahydroquinolin-6-yl]-3-methylthieno[2,3-b]pyrazine-6-carboxamide;7-amino-N-[(6S)-2-[(5S)-5-amino-2-oxa-7-azaspiro[3.4]octan-7-yl]-5,6,7,8-tetrahydroquinolin-6-yl]-3-methylthieno[2,3-b]pyrazine-6-carboxamide;3-amino-N-[(6S)-2-[(3S,4R)-3-amino-4-(trifluoromethyl)pyrrolidin-1-yl]-5,6,7,8-tetrahydroquinolin-6-yl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-N-[(6S)-2-[(3R,4S)-3-amino-4-(trifluoromethyl)pyrrolidin-1-yl]-5,6,7,8-tetrahydroquinolin-6-yl]-6-methylthieno[2,3-b]pyridine-2-carboxamide.

Molecular Properties

• Compound Name: 7-amino-N-[(6S)-2-[(5R)-5-amino-2-oxa-7-azaspiro[3.4]octan-7-yl]-5,6,7,8-tetrahydroquinolin-6-yl]-3-methylthieno[2,3-b]pyrazine-6-carboxamide;7-amino-N-[(6S)-2-[(5S)-5-amino-2-oxa-7-azaspiro[3.4]octan-7-yl]-5,6,7,8-tetrahydroquinolin-6-yl]-3-methylthieno[2,3-b]pyrazine-6-carboxamide;3-amino-N-[(6S)-2-[(3S,4R)-3-amino-4-(trifluoromethyl)pyrrolidin-1-yl]-5,6,7,8-tetrahydroquinolin-6-yl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-N-[(6S)-2-[(3R,4S)-3-amino-4-(trifluoromethyl)pyrrolidin-1-yl]-5,6,7,8-tetrahydroquinolin-6-yl]-6-methylthieno[2,3-b]pyridine-2-carboxamide
• PubChem CID: 167603441
• Molecular Formula: C92H104F6N26O6S4
• Molecular Weight: 1912.28 g/mol
• Exact Mass: 1910.74
• IUPAC Name: 7-amino-N-[(6S)-2-[(5R)-5-amino-2-oxa-7-azaspiro[3.4]octan-7-yl]-5,6,7,8-tetrahydroquinolin-6-yl]-3-methylthieno[2,3-b]pyrazine-6-carboxamide;7-amino-N-[(6S)-2-[(5S)-5-amino-2-oxa-7-azaspiro[3.4]octan-7-yl]-5,6,7,8-tetrahydroquinolin-6-yl]-3-methylthieno[2,3-b]pyrazine-6-carboxamide;3-amino-N-[(6S)-2-[(3S,4R)-3-amino-4-(trifluoromethyl)pyrrolidin-1-yl]-5,6,7,8-tetrahydroquinolin-6-yl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-N-[(6S)-2-[(3R,4S)-3-amino-4-(trifluoromethyl)pyrrolidin-1-yl]-5,6,7,8-tetrahydroquinolin-6-yl]-6-methylthieno[2,3-b]pyridine-2-carboxamide
• SMILES: Cc1ccc2c(N)c(C(=O)N[C@H]3CCc4nc(N5C[C@@H](N)[C@H](C(F)(F)F)C5)ccc4C3)sc2n1.Cc1ccc2c(N)c(C(=O)N[C@H]3CCc4nc(N5C[C@H](N)[C@@H](C(F)(F)F)C5)ccc4C3)sc2n1.Cc1cnc2c(N)c(C(=O)N[C@H]3CCc4nc(N5C[C@@H](N)C6(COC6)C5)ccc4C3)sc2n1.Cc1cnc2c(N)c(C(=O)N[C@H]3CCc4nc(N5C[C@H](N)C6(COC6)C5)ccc4C3)sc2n1
• InChI: InChI=1S/2C23H25F3N6OS.2C23H27N7O2S/c2*1-11-2-5-14-19(28)20(34-22(14)29-11)21(33)30-13-4-6-17-12(8-13)3-7-18(31-17)32-9-15(16(27)10-32)23(24,25)26;2*1-12-7-26-19-18(25)20(33-22(19)27-12)21(31)28-14-3-4-15-13(6-14)2-5-17(29-15)30-8-16(24)23(9-30)10-32-11-23/h2*2-3,5,7,13,15-16H,4,6,8-10,27-28H2,1H3,(H,30,33);2*2,5,7,14,16H,3-4,6,8-11,24-25H2,1H3,(H,28,31)/t13-,15+,16+;13-,15-,16-;14-,16+;14-,16-/m0000/s1
• InChIKey: KAYRLMMVXXFVOM-KHIHIEGYSA-N
• XLogP: 9.25
• TPSA: 484.88 Ų
• H-Bond Donors: 12
• H-Bond Acceptors: 32
• Rotatable Bonds: 12
• Heavy Atoms: 134
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	1912.28
LogP ≤ 5	9.25
H-Bond Donors ≤ 5	12
H-Bond Acceptors ≤ 10	32

Frequently Asked Questions

What is the IUPAC name of 7-amino-N-[(6S)-2-[(5R)-5-amino-2-oxa-7-azaspiro[3.4]octan-7-yl]-5,6,7,8-tetrahydroquinolin-6-yl]-3-methylthieno[2,3-b]pyrazine-6-carboxamide;7-amino-N-[(6S)-2-[(5S)-5-amino-2-oxa-7-azaspiro[3.4]octan-7-yl]-5,6,7,8-tetrahydroquinolin-6-yl]-3-methylthieno[2,3-b]pyrazine-6-carboxamide;3-amino-N-[(6S)-2-[(3S,4R)-3-amino-4-(trifluoromethyl)pyrrolidin-1-yl]-5,6,7,8-tetrahydroquinolin-6-yl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-N-[(6S)-2-[(3R,4S)-3-amino-4-(trifluoromethyl)pyrrolidin-1-yl]-5,6,7,8-tetrahydroquinolin-6-yl]-6-methylthieno[2,3-b]pyridine-2-carboxamide?

The IUPAC name of 7-amino-N-[(6S)-2-[(5R)-5-amino-2-oxa-7-azaspiro[3.4]octan-7-yl]-5,6,7,8-tetrahydroquinolin-6-yl]-3-methylthieno[2,3-b]pyrazine-6-carboxamide;7-amino-N-[(6S)-2-[(5S)-5-amino-2-oxa-7-azaspiro[3.4]octan-7-yl]-5,6,7,8-tetrahydroquinolin-6-yl]-3-methylthieno[2,3-b]pyrazine-6-carboxamide;3-amino-N-[(6S)-2-[(3S,4R)-3-amino-4-(trifluoromethyl)pyrrolidin-1-yl]-5,6,7,8-tetrahydroquinolin-6-yl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-N-[(6S)-2-[(3R,4S)-3-amino-4-(trifluoromethyl)pyrrolidin-1-yl]-5,6,7,8-tetrahydroquinolin-6-yl]-6-methylthieno[2,3-b]pyridine-2-carboxamide (CID 167603441) is 7-amino-N-[(6S)-2-[(5R)-5-amino-2-oxa-7-azaspiro[3.4]octan-7-yl]-5,6,7,8-tetrahydroquinolin-6-yl]-3-methylthieno[2,3-b]pyrazine-6-carboxamide;7-amino-N-[(6S)-2-[(5S)-5-amino-2-oxa-7-azaspiro[3.4]octan-7-yl]-5,6,7,8-tetrahydroquinolin-6-yl]-3-methylthieno[2,3-b]pyrazine-6-carboxamide;3-amino-N-[(6S)-2-[(3S,4R)-3-amino-4-(trifluoromethyl)pyrrolidin-1-yl]-5,6,7,8-tetrahydroquinolin-6-yl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-N-[(6S)-2-[(3R,4S)-3-amino-4-(trifluoromethyl)pyrrolidin-1-yl]-5,6,7,8-tetrahydroquinolin-6-yl]-6-methylthieno[2,3-b]pyridine-2-carboxamide.

What is the SMILES notation for 7-amino-N-[(6S)-2-[(5R)-5-amino-2-oxa-7-azaspiro[3.4]octan-7-yl]-5,6,7,8-tetrahydroquinolin-6-yl]-3-methylthieno[2,3-b]pyrazine-6-carboxamide;7-amino-N-[(6S)-2-[(5S)-5-amino-2-oxa-7-azaspiro[3.4]octan-7-yl]-5,6,7,8-tetrahydroquinolin-6-yl]-3-methylthieno[2,3-b]pyrazine-6-carboxamide;3-amino-N-[(6S)-2-[(3S,4R)-3-amino-4-(trifluoromethyl)pyrrolidin-1-yl]-5,6,7,8-tetrahydroquinolin-6-yl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-N-[(6S)-2-[(3R,4S)-3-amino-4-(trifluoromethyl)pyrrolidin-1-yl]-5,6,7,8-tetrahydroquinolin-6-yl]-6-methylthieno[2,3-b]pyridine-2-carboxamide?

The canonical SMILES for 7-amino-N-[(6S)-2-[(5R)-5-amino-2-oxa-7-azaspiro[3.4]octan-7-yl]-5,6,7,8-tetrahydroquinolin-6-yl]-3-methylthieno[2,3-b]pyrazine-6-carboxamide;7-amino-N-[(6S)-2-[(5S)-5-amino-2-oxa-7-azaspiro[3.4]octan-7-yl]-5,6,7,8-tetrahydroquinolin-6-yl]-3-methylthieno[2,3-b]pyrazine-6-carboxamide;3-amino-N-[(6S)-2-[(3S,4R)-3-amino-4-(trifluoromethyl)pyrrolidin-1-yl]-5,6,7,8-tetrahydroquinolin-6-yl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-N-[(6S)-2-[(3R,4S)-3-amino-4-(trifluoromethyl)pyrrolidin-1-yl]-5,6,7,8-tetrahydroquinolin-6-yl]-6-methylthieno[2,3-b]pyridine-2-carboxamide is Cc1ccc2c(N)c(C(=O)N[C@H]3CCc4nc(N5C[C@@H](N)[C@H](C(F)(F)F)C5)ccc4C3)sc2n1.Cc1ccc2c(N)c(C(=O)N[C@H]3CCc4nc(N5C[C@H](N)[C@@H](C(F)(F)F)C5)ccc4C3)sc2n1.Cc1cnc2c(N)c(C(=O)N[C@H]3CCc4nc(N5C[C@@H](N)C6(COC6)C5)ccc4C3)sc2n1.Cc1cnc2c(N)c(C(=O)N[C@H]3CCc4nc(N5C[C@H](N)C6(COC6)C5)ccc4C3)sc2n1.

What is the InChIKey of 7-amino-N-[(6S)-2-[(5R)-5-amino-2-oxa-7-azaspiro[3.4]octan-7-yl]-5,6,7,8-tetrahydroquinolin-6-yl]-3-methylthieno[2,3-b]pyrazine-6-carboxamide;7-amino-N-[(6S)-2-[(5S)-5-amino-2-oxa-7-azaspiro[3.4]octan-7-yl]-5,6,7,8-tetrahydroquinolin-6-yl]-3-methylthieno[2,3-b]pyrazine-6-carboxamide;3-amino-N-[(6S)-2-[(3S,4R)-3-amino-4-(trifluoromethyl)pyrrolidin-1-yl]-5,6,7,8-tetrahydroquinolin-6-yl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-N-[(6S)-2-[(3R,4S)-3-amino-4-(trifluoromethyl)pyrrolidin-1-yl]-5,6,7,8-tetrahydroquinolin-6-yl]-6-methylthieno[2,3-b]pyridine-2-carboxamide?

The InChIKey is KAYRLMMVXXFVOM-KHIHIEGYSA-N. The full InChI is InChI=1S/2C23H25F3N6OS.2C23H27N7O2S/c2*1-11-2-5-14-19(28)20(34-22(14)29-11)21(33)30-13-4-6-17-12(8-13)3-7-18(31-17)32-9-15(16(27)10-32)23(24,25)26;2*1-12-7-26-19-18(25)20(33-22(19)27-12)21(31)28-14-3-4-15-13(6-14)2-5-17(29-15)30-8-16(24)23(9-30)10-32-11-23/h2*2-3,5,7,13,15-16H,4,6,8-10,27-28H2,1H3,(H,30,33);2*2,5,7,14,16H,3-4,6,8-11,24-25H2,1H3,(H,28,31)/t13-,15+,16+;13-,15-,16-;14-,16+;14-,16-/m0000/s1.

What are the key properties of 7-amino-N-[(6S)-2-[(5R)-5-amino-2-oxa-7-azaspiro[3.4]octan-7-yl]-5,6,7,8-tetrahydroquinolin-6-yl]-3-methylthieno[2,3-b]pyrazine-6-carboxamide;7-amino-N-[(6S)-2-[(5S)-5-amino-2-oxa-7-azaspiro[3.4]octan-7-yl]-5,6,7,8-tetrahydroquinolin-6-yl]-3-methylthieno[2,3-b]pyrazine-6-carboxamide;3-amino-N-[(6S)-2-[(3S,4R)-3-amino-4-(trifluoromethyl)pyrrolidin-1-yl]-5,6,7,8-tetrahydroquinolin-6-yl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-N-[(6S)-2-[(3R,4S)-3-amino-4-(trifluoromethyl)pyrrolidin-1-yl]-5,6,7,8-tetrahydroquinolin-6-yl]-6-methylthieno[2,3-b]pyridine-2-carboxamide?

7-amino-N-[(6S)-2-[(5R)-5-amino-2-oxa-7-azaspiro[3.4]octan-7-yl]-5,6,7,8-tetrahydroquinolin-6-yl]-3-methylthieno[2,3-b]pyrazine-6-carboxamide;7-amino-N-[(6S)-2-[(5S)-5-amino-2-oxa-7-azaspiro[3.4]octan-7-yl]-5,6,7,8-tetrahydroquinolin-6-yl]-3-methylthieno[2,3-b]pyrazine-6-carboxamide;3-amino-N-[(6S)-2-[(3S,4R)-3-amino-4-(trifluoromethyl)pyrrolidin-1-yl]-5,6,7,8-tetrahydroquinolin-6-yl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-N-[(6S)-2-[(3R,4S)-3-amino-4-(trifluoromethyl)pyrrolidin-1-yl]-5,6,7,8-tetrahydroquinolin-6-yl]-6-methylthieno[2,3-b]pyridine-2-carboxamide has a molecular weight of 1912.28 g/mol, XLogP of 9.25, 12 rotatable bonds, 12 hydrogen bond donors, and 32 hydrogen bond acceptors.

Where does this data come from?

All data for 7-amino-N-[(6S)-2-[(5R)-5-amino-2-oxa-7-azaspiro[3.4]octan-7-yl]-5,6,7,8-tetrahydroquinolin-6-yl]-3-methylthieno[2,3-b]pyrazine-6-carboxamide;7-amino-N-[(6S)-2-[(5S)-5-amino-2-oxa-7-azaspiro[3.4]octan-7-yl]-5,6,7,8-tetrahydroquinolin-6-yl]-3-methylthieno[2,3-b]pyrazine-6-carboxamide;3-amino-N-[(6S)-2-[(3S,4R)-3-amino-4-(trifluoromethyl)pyrrolidin-1-yl]-5,6,7,8-tetrahydroquinolin-6-yl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-N-[(6S)-2-[(3R,4S)-3-amino-4-(trifluoromethyl)pyrrolidin-1-yl]-5,6,7,8-tetrahydroquinolin-6-yl]-6-methylthieno[2,3-b]pyridine-2-carboxamide is sourced from PubChem (CID 167603441), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).