N-[(1R)-1-(4-cyano-1H-indazol-7-yl)ethyl]-6-ethoxy-5-(3-fluorophenyl)-N-methylpyridine-2-carboxamide;N-[(1R)-1-(4-cyano-1H-indazol-7-yl)ethyl]-6-ethoxy-N-methyl-5-phenylpyridine-2-carboxamide;4-(3-cyanophenyl)-N-[(4-cyano-1H-pyrazolo[4,5-c]pyridin-7-yl)methyl]-3-ethoxy-N-methylbenzamide;5-(3-cyanophenyl)-N-[(4-cyano-1H-pyrazolo[4,5-c]pyridin-7-yl)methyl]-6-ethoxy-N-methylpyridine-2-carboxamide;N-[[4-(fluoromethyl)-1H-pyrazolo[4,5-c]pyridin-7-yl]methyl]-N-methyl-3-(oxetan-3-yloxy)-4-phenylbenzamide

C124H107F2N27O11 — CID 167614417

About N-[(1R)-1-(4-cyano-1H-indazol-7-yl)ethyl]-6-ethoxy-5-(3-fluorophenyl)-N-methylpyridine-2-carboxamide;N-[(1R)-1-(4-cyano-1H-indazol-7-yl)ethyl]-6-ethoxy-N-methyl-5-phenylpyridine-2-carboxamide;4-(3-cyanophenyl)-N-[(4-cyano-1H-pyrazolo[4,5-c]pyridin-7-yl)methyl]-3-ethoxy-N-methylbenzamide;5-(3-cyanophenyl)-N-[(4-cyano-1H-pyrazolo[4,5-c]pyridin-7-yl)methyl]-6-ethoxy-N-methylpyridine-2-carboxamide;N-[[4-(fluoromethyl)-1H-pyrazolo[4,5-c]pyridin-7-yl]methyl]-N-methyl-3-(oxetan-3-yloxy)-4-phenylbenzamide

N-[(1R)-1-(4-cyano-1H-indazol-7-yl)ethyl]-6-ethoxy-5-(3-fluorophenyl)-N-methylpyridine-2-carboxamide;N-[(1R)-1-(4-cyano-1H-indazol-7-yl)ethyl]-6-ethoxy-N-methyl-5-phenylpyridine-2-carboxamide;4-(3-cyanophenyl)-N-[(4-cyano-1H-pyrazolo[4,5-c]pyridin-7-yl)methyl]-3-ethoxy-N-methylbenzamide;5-(3-cyanophenyl)-N-[(4-cyano-1H-pyrazolo[4,5-c]pyridin-7-yl)methyl]-6-ethoxy-N-methylpyridine-2-carboxamide;N-[[4-(fluoromethyl)-1H-pyrazolo[4,5-c]pyridin-7-yl]methyl]-N-methyl-3-(oxetan-3-yloxy)-4-phenylbenzamide (PubChem CID 167614417) has the molecular formula C124H107F2N27O11 and a molecular weight of 2189.39 g/mol. Its IUPAC name is N-[(1R)-1-(4-cyano-1H-indazol-7-yl)ethyl]-6-ethoxy-5-(3-fluorophenyl)-N-methylpyridine-2-carboxamide;N-[(1R)-1-(4-cyano-1H-indazol-7-yl)ethyl]-6-ethoxy-N-methyl-5-phenylpyridine-2-carboxamide;4-(3-cyanophenyl)-N-[(4-cyano-1H-pyrazolo[4,5-c]pyridin-7-yl)methyl]-3-ethoxy-N-methylbenzamide;5-(3-cyanophenyl)-N-[(4-cyano-1H-pyrazolo[4,5-c]pyridin-7-yl)methyl]-6-ethoxy-N-methylpyridine-2-carboxamide;N-[[4-(fluoromethyl)-1H-pyrazolo[4,5-c]pyridin-7-yl]methyl]-N-methyl-3-(oxetan-3-yloxy)-4-phenylbenzamide.

Molecular Properties

• Compound Name: N-[(1R)-1-(4-cyano-1H-indazol-7-yl)ethyl]-6-ethoxy-5-(3-fluorophenyl)-N-methylpyridine-2-carboxamide;N-[(1R)-1-(4-cyano-1H-indazol-7-yl)ethyl]-6-ethoxy-N-methyl-5-phenylpyridine-2-carboxamide;4-(3-cyanophenyl)-N-[(4-cyano-1H-pyrazolo[4,5-c]pyridin-7-yl)methyl]-3-ethoxy-N-methylbenzamide;5-(3-cyanophenyl)-N-[(4-cyano-1H-pyrazolo[4,5-c]pyridin-7-yl)methyl]-6-ethoxy-N-methylpyridine-2-carboxamide;N-[[4-(fluoromethyl)-1H-pyrazolo[4,5-c]pyridin-7-yl]methyl]-N-methyl-3-(oxetan-3-yloxy)-4-phenylbenzamide
• PubChem CID: 167614417
• Molecular Formula: C124H107F2N27O11
• Molecular Weight: 2189.39 g/mol
• Exact Mass: 2187.86
• IUPAC Name: N-[(1R)-1-(4-cyano-1H-indazol-7-yl)ethyl]-6-ethoxy-5-(3-fluorophenyl)-N-methylpyridine-2-carboxamide;N-[(1R)-1-(4-cyano-1H-indazol-7-yl)ethyl]-6-ethoxy-N-methyl-5-phenylpyridine-2-carboxamide;4-(3-cyanophenyl)-N-[(4-cyano-1H-pyrazolo[4,5-c]pyridin-7-yl)methyl]-3-ethoxy-N-methylbenzamide;5-(3-cyanophenyl)-N-[(4-cyano-1H-pyrazolo[4,5-c]pyridin-7-yl)methyl]-6-ethoxy-N-methylpyridine-2-carboxamide;N-[[4-(fluoromethyl)-1H-pyrazolo[4,5-c]pyridin-7-yl]methyl]-N-methyl-3-(oxetan-3-yloxy)-4-phenylbenzamide
• SMILES: CCOc1cc(C(=O)N(C)Cc2cnc(C#N)c3cn[nH]c23)ccc1-c1cccc(C#N)c1.CCOc1nc(C(=O)N(C)Cc2cnc(C#N)c3cn[nH]c23)ccc1-c1cccc(C#N)c1.CCOc1nc(C(=O)N(C)[C@H](C)c2ccc(C#N)c3cn[nH]c23)ccc1-c1cccc(F)c1.CCOc1nc(C(=O)N(C)[C@H](C)c2ccc(C#N)c3cn[nH]c23)ccc1-c1ccccc1.CN(Cc1cnc(CF)c2cn[nH]c12)C(=O)c1ccc(-c2ccccc2)c(OC2COC2)c1
• InChI: InChI=1S/C25H22FN5O2.C25H23FN4O3.C25H20N6O2.C25H23N5O2.C24H19N7O2/c1-4-33-24-20(16-6-5-7-18(26)12-16)10-11-22(29-24)25(32)31(3)15(2)19-9-8-17(13-27)21-14-28-30-23(19)21;1-30(13-18-11-27-22(10-26)21-12-28-29-24(18)21)25(31)17-7-8-20(16-5-3-2-4-6-16)23(9-17)33-19-14-32-15-19;1-3-33-23-10-18(7-8-20(23)17-6-4-5-16(9-17)11-26)25(32)31(2)15-19-13-28-22(12-27)21-14-29-30-24(19)21;1-4-32-24-20(17-8-6-5-7-9-17)12-13-22(28-24)25(31)30(3)16(2)19-11-10-18(14-26)21-15-27-29-23(19)21;1-3-33-23-18(16-6-4-5-15(9-16)10-25)7-8-20(29-23)24(32)31(2)14-17-12-27-21(11-26)19-13-28-30-22(17)19/h5-12,14-15H,4H2,1-3H3,(H,28,30);2-9,11-12,19H,10,13-15H2,1H3,(H,28,29);4-10,13-14H,3,15H2,1-2H3,(H,29,30);5-13,15-16H,4H2,1-3H3,(H,27,29);4-9,12-13H,3,14H2,1-2H3,(H,28,30)/t15-;;;16-;/m1..1./s1
• InChIKey: LNNKZRWJNHFWGY-MRKDVLPVSA-N
• XLogP: 21.21
• TPSA: 520.41 Ų
• H-Bond Donors: 5
• H-Bond Acceptors: 28
• Rotatable Bonds: 31
• Heavy Atoms: 164
• Complexity: —

Lipinski Rule of Five

3 violations

Rule	Value
MW ≤ 500	2189.39
LogP ≤ 5	21.21
H-Bond Donors ≤ 5	5
H-Bond Acceptors ≤ 10	28

Frequently Asked Questions

What is the IUPAC name of N-[(1R)-1-(4-cyano-1H-indazol-7-yl)ethyl]-6-ethoxy-5-(3-fluorophenyl)-N-methylpyridine-2-carboxamide;N-[(1R)-1-(4-cyano-1H-indazol-7-yl)ethyl]-6-ethoxy-N-methyl-5-phenylpyridine-2-carboxamide;4-(3-cyanophenyl)-N-[(4-cyano-1H-pyrazolo[4,5-c]pyridin-7-yl)methyl]-3-ethoxy-N-methylbenzamide;5-(3-cyanophenyl)-N-[(4-cyano-1H-pyrazolo[4,5-c]pyridin-7-yl)methyl]-6-ethoxy-N-methylpyridine-2-carboxamide;N-[[4-(fluoromethyl)-1H-pyrazolo[4,5-c]pyridin-7-yl]methyl]-N-methyl-3-(oxetan-3-yloxy)-4-phenylbenzamide?

The IUPAC name of N-[(1R)-1-(4-cyano-1H-indazol-7-yl)ethyl]-6-ethoxy-5-(3-fluorophenyl)-N-methylpyridine-2-carboxamide;N-[(1R)-1-(4-cyano-1H-indazol-7-yl)ethyl]-6-ethoxy-N-methyl-5-phenylpyridine-2-carboxamide;4-(3-cyanophenyl)-N-[(4-cyano-1H-pyrazolo[4,5-c]pyridin-7-yl)methyl]-3-ethoxy-N-methylbenzamide;5-(3-cyanophenyl)-N-[(4-cyano-1H-pyrazolo[4,5-c]pyridin-7-yl)methyl]-6-ethoxy-N-methylpyridine-2-carboxamide;N-[[4-(fluoromethyl)-1H-pyrazolo[4,5-c]pyridin-7-yl]methyl]-N-methyl-3-(oxetan-3-yloxy)-4-phenylbenzamide (CID 167614417) is N-[(1R)-1-(4-cyano-1H-indazol-7-yl)ethyl]-6-ethoxy-5-(3-fluorophenyl)-N-methylpyridine-2-carboxamide;N-[(1R)-1-(4-cyano-1H-indazol-7-yl)ethyl]-6-ethoxy-N-methyl-5-phenylpyridine-2-carboxamide;4-(3-cyanophenyl)-N-[(4-cyano-1H-pyrazolo[4,5-c]pyridin-7-yl)methyl]-3-ethoxy-N-methylbenzamide;5-(3-cyanophenyl)-N-[(4-cyano-1H-pyrazolo[4,5-c]pyridin-7-yl)methyl]-6-ethoxy-N-methylpyridine-2-carboxamide;N-[[4-(fluoromethyl)-1H-pyrazolo[4,5-c]pyridin-7-yl]methyl]-N-methyl-3-(oxetan-3-yloxy)-4-phenylbenzamide.

What is the SMILES notation for N-[(1R)-1-(4-cyano-1H-indazol-7-yl)ethyl]-6-ethoxy-5-(3-fluorophenyl)-N-methylpyridine-2-carboxamide;N-[(1R)-1-(4-cyano-1H-indazol-7-yl)ethyl]-6-ethoxy-N-methyl-5-phenylpyridine-2-carboxamide;4-(3-cyanophenyl)-N-[(4-cyano-1H-pyrazolo[4,5-c]pyridin-7-yl)methyl]-3-ethoxy-N-methylbenzamide;5-(3-cyanophenyl)-N-[(4-cyano-1H-pyrazolo[4,5-c]pyridin-7-yl)methyl]-6-ethoxy-N-methylpyridine-2-carboxamide;N-[[4-(fluoromethyl)-1H-pyrazolo[4,5-c]pyridin-7-yl]methyl]-N-methyl-3-(oxetan-3-yloxy)-4-phenylbenzamide?

The canonical SMILES for N-[(1R)-1-(4-cyano-1H-indazol-7-yl)ethyl]-6-ethoxy-5-(3-fluorophenyl)-N-methylpyridine-2-carboxamide;N-[(1R)-1-(4-cyano-1H-indazol-7-yl)ethyl]-6-ethoxy-N-methyl-5-phenylpyridine-2-carboxamide;4-(3-cyanophenyl)-N-[(4-cyano-1H-pyrazolo[4,5-c]pyridin-7-yl)methyl]-3-ethoxy-N-methylbenzamide;5-(3-cyanophenyl)-N-[(4-cyano-1H-pyrazolo[4,5-c]pyridin-7-yl)methyl]-6-ethoxy-N-methylpyridine-2-carboxamide;N-[[4-(fluoromethyl)-1H-pyrazolo[4,5-c]pyridin-7-yl]methyl]-N-methyl-3-(oxetan-3-yloxy)-4-phenylbenzamide is CCOc1cc(C(=O)N(C)Cc2cnc(C#N)c3cn[nH]c23)ccc1-c1cccc(C#N)c1.CCOc1nc(C(=O)N(C)Cc2cnc(C#N)c3cn[nH]c23)ccc1-c1cccc(C#N)c1.CCOc1nc(C(=O)N(C)[C@H](C)c2ccc(C#N)c3cn[nH]c23)ccc1-c1cccc(F)c1.CCOc1nc(C(=O)N(C)[C@H](C)c2ccc(C#N)c3cn[nH]c23)ccc1-c1ccccc1.CN(Cc1cnc(CF)c2cn[nH]c12)C(=O)c1ccc(-c2ccccc2)c(OC2COC2)c1.

What is the InChIKey of N-[(1R)-1-(4-cyano-1H-indazol-7-yl)ethyl]-6-ethoxy-5-(3-fluorophenyl)-N-methylpyridine-2-carboxamide;N-[(1R)-1-(4-cyano-1H-indazol-7-yl)ethyl]-6-ethoxy-N-methyl-5-phenylpyridine-2-carboxamide;4-(3-cyanophenyl)-N-[(4-cyano-1H-pyrazolo[4,5-c]pyridin-7-yl)methyl]-3-ethoxy-N-methylbenzamide;5-(3-cyanophenyl)-N-[(4-cyano-1H-pyrazolo[4,5-c]pyridin-7-yl)methyl]-6-ethoxy-N-methylpyridine-2-carboxamide;N-[[4-(fluoromethyl)-1H-pyrazolo[4,5-c]pyridin-7-yl]methyl]-N-methyl-3-(oxetan-3-yloxy)-4-phenylbenzamide?

The InChIKey is LNNKZRWJNHFWGY-MRKDVLPVSA-N. The full InChI is InChI=1S/C25H22FN5O2.C25H23FN4O3.C25H20N6O2.C25H23N5O2.C24H19N7O2/c1-4-33-24-20(16-6-5-7-18(26)12-16)10-11-22(29-24)25(32)31(3)15(2)19-9-8-17(13-27)21-14-28-30-23(19)21;1-30(13-18-11-27-22(10-26)21-12-28-29-24(18)21)25(31)17-7-8-20(16-5-3-2-4-6-16)23(9-17)33-19-14-32-15-19;1-3-33-23-10-18(7-8-20(23)17-6-4-5-16(9-17)11-26)25(32)31(2)15-19-13-28-22(12-27)21-14-29-30-24(19)21;1-4-32-24-20(17-8-6-5-7-9-17)12-13-22(28-24)25(31)30(3)16(2)19-11-10-18(14-26)21-15-27-29-23(19)21;1-3-33-23-18(16-6-4-5-15(9-16)10-25)7-8-20(29-23)24(32)31(2)14-17-12-27-21(11-26)19-13-28-30-22(17)19/h5-12,14-15H,4H2,1-3H3,(H,28,30);2-9,11-12,19H,10,13-15H2,1H3,(H,28,29);4-10,13-14H,3,15H2,1-2H3,(H,29,30);5-13,15-16H,4H2,1-3H3,(H,27,29);4-9,12-13H,3,14H2,1-2H3,(H,28,30)/t15-;;;16-;/m1..1./s1.

What are the key properties of N-[(1R)-1-(4-cyano-1H-indazol-7-yl)ethyl]-6-ethoxy-5-(3-fluorophenyl)-N-methylpyridine-2-carboxamide;N-[(1R)-1-(4-cyano-1H-indazol-7-yl)ethyl]-6-ethoxy-N-methyl-5-phenylpyridine-2-carboxamide;4-(3-cyanophenyl)-N-[(4-cyano-1H-pyrazolo[4,5-c]pyridin-7-yl)methyl]-3-ethoxy-N-methylbenzamide;5-(3-cyanophenyl)-N-[(4-cyano-1H-pyrazolo[4,5-c]pyridin-7-yl)methyl]-6-ethoxy-N-methylpyridine-2-carboxamide;N-[[4-(fluoromethyl)-1H-pyrazolo[4,5-c]pyridin-7-yl]methyl]-N-methyl-3-(oxetan-3-yloxy)-4-phenylbenzamide?

N-[(1R)-1-(4-cyano-1H-indazol-7-yl)ethyl]-6-ethoxy-5-(3-fluorophenyl)-N-methylpyridine-2-carboxamide;N-[(1R)-1-(4-cyano-1H-indazol-7-yl)ethyl]-6-ethoxy-N-methyl-5-phenylpyridine-2-carboxamide;4-(3-cyanophenyl)-N-[(4-cyano-1H-pyrazolo[4,5-c]pyridin-7-yl)methyl]-3-ethoxy-N-methylbenzamide;5-(3-cyanophenyl)-N-[(4-cyano-1H-pyrazolo[4,5-c]pyridin-7-yl)methyl]-6-ethoxy-N-methylpyridine-2-carboxamide;N-[[4-(fluoromethyl)-1H-pyrazolo[4,5-c]pyridin-7-yl]methyl]-N-methyl-3-(oxetan-3-yloxy)-4-phenylbenzamide has a molecular weight of 2189.39 g/mol, XLogP of 21.21, 31 rotatable bonds, 5 hydrogen bond donors, and 28 hydrogen bond acceptors.

Where does this data come from?

All data for N-[(1R)-1-(4-cyano-1H-indazol-7-yl)ethyl]-6-ethoxy-5-(3-fluorophenyl)-N-methylpyridine-2-carboxamide;N-[(1R)-1-(4-cyano-1H-indazol-7-yl)ethyl]-6-ethoxy-N-methyl-5-phenylpyridine-2-carboxamide;4-(3-cyanophenyl)-N-[(4-cyano-1H-pyrazolo[4,5-c]pyridin-7-yl)methyl]-3-ethoxy-N-methylbenzamide;5-(3-cyanophenyl)-N-[(4-cyano-1H-pyrazolo[4,5-c]pyridin-7-yl)methyl]-6-ethoxy-N-methylpyridine-2-carboxamide;N-[[4-(fluoromethyl)-1H-pyrazolo[4,5-c]pyridin-7-yl]methyl]-N-methyl-3-(oxetan-3-yloxy)-4-phenylbenzamide is sourced from PubChem (CID 167614417), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).