7-[5-amino-6-(1-ethylpyrazol-4-yl)oxypyrazin-2-yl]-N,2-dimethyl-3,4-dihydro-1H-isoquinolin-5-amine;3-[(2-amino-4-pyridinyl)methoxy]-5-[2-methyl-5-(trifluoromethyl)-3,4-dihydro-1H-isoquinolin-7-yl]pyrazin-2-amine;3-[1-(cyclopropylmethyl)pyrazol-4-yl]oxy-5-(2,5-dimethyl-3,4-dihydro-1H-isoquinolin-7-yl)pyrazin-2-amine;5-(2,5-dimethyl-3,4-dihydro-1H-isoquinolin-7-yl)-3-(1-propan-2-ylpyrazol-4-yl)oxypyrazin-2-amine;3-(1-ethylpyrazol-4-yl)oxy-5-(5-methoxy-2-methyl-3,4-dihydro-1H-isoquinolin-7-yl)pyrazin-2-amine

C104H122F3N31O6 — CID 167623280

IUPAC7-[5-amino-6-(1-ethylpyrazol-4-yl)oxypyrazin-2-yl]-N,2-dimethyl-3,4-dihydro-1H-isoquinolin-5-amine;3-[(2-amino-4-pyridinyl)methoxy]-5-[2-methyl-5-(trifluoromethyl)-3,4-dihydro-1H-isoquinolin-7-yl]pyrazin-2-amine;3-[1-(cyclopropylmethyl)pyrazol-4-yl]oxy-5-(2,5-dimethyl-3,4-dihydro-1H-isoquinolin-7-yl)pyrazin-2-amine;5-(2,5-dimethyl-3,4-dihydro-1H-isoquinolin-7-yl)-3-(1-propan-2-ylpyrazol-4-yl)oxypyrazin-2-amine;3-(1-ethylpyrazol-4-yl)oxy-5-(5-methoxy-2-methyl-3,4-dihydro-1H-isoquinolin-7-yl)pyrazin-2-amine
SMILESCCn1cc(Oc2nc(-c3cc4c(c(NC)c3)CCN(C)C4)cnc2N)cn1.CCn1cc(Oc2nc(-c3cc4c(c(OC)c3)CCN(C)C4)cnc2N)cn1.CN1CCc2c(cc(-c3cnc(N)c(OCc4ccnc(N)c4)n3)cc2C(F)(F)F)C1.Cc1cc(-c2cnc(N)c(Oc3cnn(C(C)C)c3)n2)cc2c1CCN(C)C2.Cc1cc(-c2cnc(N)c(Oc3cnn(CC4CC4)c3)n2)cc2c1CCN(C)C2
InChIInChI=1S/C22H26N6O.C21H21F3N6O.C21H26N6O.C20H25N7O.C20H24N6O2/c1-14-7-16(8-17-12-27(2)6-5-19(14)17)20-10-24-21(23)22(26-20)29-18-9-25-28(13-18)11-15-3-4-15;1-30-5-3-15-14(10-30)7-13(8-16(15)21(22,23)24)17-9-28-19(26)20(29-17)31-11-12-2-4-27-18(25)6-12;1-13(2)27-12-17(9-24-27)28-21-20(22)23-10-19(25-21)15-7-14(3)18-5-6-26(4)11-16(18)8-15;1-4-27-12-15(9-24-27)28-20-19(21)23-10-18(25-20)13-7-14-11-26(3)6-5-16(14)17(8-13)22-2;1-4-26-12-15(9-23-26)28-20-19(21)22-10-17(24-20)13-7-14-11-25(2)6-5-16(14)18(8-13)27-3/h7-10,13,15H,3-6,11-12H2,1-2H3,(H2,23,24);2,4,6-9H,3,5,10-11H2,1H3,(H2,25,27)(H2,26,28);7-10,12-13H,5-6,11H2,1-4H3,(H2,22,23);7-10,12,22H,4-6,11H2,1-3H3,(H2,21,23);7-10,12H,4-6,11H2,1-3H3,(H2,21,22)
InChIKeyMSWCHOWIKXWHRF-UHFFFAOYSA-N
MW1959.32 g/mol
LogP15.80
Rot. Bonds23

About 7-[5-amino-6-(1-ethylpyrazol-4-yl)oxypyrazin-2-yl]-N,2-dimethyl-3,4-dihydro-1H-isoquinolin-5-amine;3-[(2-amino-4-pyridinyl)methoxy]-5-[2-methyl-5-(trifluoromethyl)-3,4-dihydro-1H-isoquinolin-7-yl]pyrazin-2-amine;3-[1-(cyclopropylmethyl)pyrazol-4-yl]oxy-5-(2,5-dimethyl-3,4-dihydro-1H-isoquinolin-7-yl)pyrazin-2-amine;5-(2,5-dimethyl-3,4-dihydro-1H-isoquinolin-7-yl)-3-(1-propan-2-ylpyrazol-4-yl)oxypyrazin-2-amine;3-(1-ethylpyrazol-4-yl)oxy-5-(5-methoxy-2-methyl-3,4-dihydro-1H-isoquinolin-7-yl)pyrazin-2-amine

7-[5-amino-6-(1-ethylpyrazol-4-yl)oxypyrazin-2-yl]-N,2-dimethyl-3,4-dihydro-1H-isoquinolin-5-amine;3-[(2-amino-4-pyridinyl)methoxy]-5-[2-methyl-5-(trifluoromethyl)-3,4-dihydro-1H-isoquinolin-7-yl]pyrazin-2-amine;3-[1-(cyclopropylmethyl)pyrazol-4-yl]oxy-5-(2,5-dimethyl-3,4-dihydro-1H-isoquinolin-7-yl)pyrazin-2-amine;5-(2,5-dimethyl-3,4-dihydro-1H-isoquinolin-7-yl)-3-(1-propan-2-ylpyrazol-4-yl)oxypyrazin-2-amine;3-(1-ethylpyrazol-4-yl)oxy-5-(5-methoxy-2-methyl-3,4-dihydro-1H-isoquinolin-7-yl)pyrazin-2-amine (PubChem CID 167623280) has the molecular formula C104H122F3N31O6 and a molecular weight of 1959.32 g/mol. Its IUPAC name is 7-[5-amino-6-(1-ethylpyrazol-4-yl)oxypyrazin-2-yl]-N,2-dimethyl-3,4-dihydro-1H-isoquinolin-5-amine;3-[(2-amino-4-pyridinyl)methoxy]-5-[2-methyl-5-(trifluoromethyl)-3,4-dihydro-1H-isoquinolin-7-yl]pyrazin-2-amine;3-[1-(cyclopropylmethyl)pyrazol-4-yl]oxy-5-(2,5-dimethyl-3,4-dihydro-1H-isoquinolin-7-yl)pyrazin-2-amine;5-(2,5-dimethyl-3,4-dihydro-1H-isoquinolin-7-yl)-3-(1-propan-2-ylpyrazol-4-yl)oxypyrazin-2-amine;3-(1-ethylpyrazol-4-yl)oxy-5-(5-methoxy-2-methyl-3,4-dihydro-1H-isoquinolin-7-yl)pyrazin-2-amine.

Molecular Properties

Compound Name7-[5-amino-6-(1-ethylpyrazol-4-yl)oxypyrazin-2-yl]-N,2-dimethyl-3,4-dihydro-1H-isoquinolin-5-amine;3-[(2-amino-4-pyridinyl)methoxy]-5-[2-methyl-5-(trifluoromethyl)-3,4-dihydro-1H-isoquinolin-7-yl]pyrazin-2-amine;3-[1-(cyclopropylmethyl)pyrazol-4-yl]oxy-5-(2,5-dimethyl-3,4-dihydro-1H-isoquinolin-7-yl)pyrazin-2-amine;5-(2,5-dimethyl-3,4-dihydro-1H-isoquinolin-7-yl)-3-(1-propan-2-ylpyrazol-4-yl)oxypyrazin-2-amine;3-(1-ethylpyrazol-4-yl)oxy-5-(5-methoxy-2-methyl-3,4-dihydro-1H-isoquinolin-7-yl)pyrazin-2-amine
PubChem CID167623280
Molecular FormulaC104H122F3N31O6
Molecular Weight1959.32 g/mol
Exact Mass1958.01
IUPAC Name7-[5-amino-6-(1-ethylpyrazol-4-yl)oxypyrazin-2-yl]-N,2-dimethyl-3,4-dihydro-1H-isoquinolin-5-amine;3-[(2-amino-4-pyridinyl)methoxy]-5-[2-methyl-5-(trifluoromethyl)-3,4-dihydro-1H-isoquinolin-7-yl]pyrazin-2-amine;3-[1-(cyclopropylmethyl)pyrazol-4-yl]oxy-5-(2,5-dimethyl-3,4-dihydro-1H-isoquinolin-7-yl)pyrazin-2-amine;5-(2,5-dimethyl-3,4-dihydro-1H-isoquinolin-7-yl)-3-(1-propan-2-ylpyrazol-4-yl)oxypyrazin-2-amine;3-(1-ethylpyrazol-4-yl)oxy-5-(5-methoxy-2-methyl-3,4-dihydro-1H-isoquinolin-7-yl)pyrazin-2-amine
SMILESCCn1cc(Oc2nc(-c3cc4c(c(NC)c3)CCN(C)C4)cnc2N)cn1.CCn1cc(Oc2nc(-c3cc4c(c(OC)c3)CCN(C)C4)cnc2N)cn1.CN1CCc2c(cc(-c3cnc(N)c(OCc4ccnc(N)c4)n3)cc2C(F)(F)F)C1.Cc1cc(-c2cnc(N)c(Oc3cnn(C(C)C)c3)n2)cc2c1CCN(C)C2.Cc1cc(-c2cnc(N)c(Oc3cnn(CC4CC4)c3)n2)cc2c1CCN(C)C2
InChIInChI=1S/C22H26N6O.C21H21F3N6O.C21H26N6O.C20H25N7O.C20H24N6O2/c1-14-7-16(8-17-12-27(2)6-5-19(14)17)20-10-24-21(23)22(26-20)29-18-9-25-28(13-18)11-15-3-4-15;1-30-5-3-15-14(10-30)7-13(8-16(15)21(22,23)24)17-9-28-19(26)20(29-17)31-11-12-2-4-27-18(25)6-12;1-13(2)27-12-17(9-24-27)28-21-20(22)23-10-19(25-21)15-7-14(3)18-5-6-26(4)11-16(18)8-15;1-4-27-12-15(9-24-27)28-20-19(21)23-10-18(25-20)13-7-14-11-26(3)6-5-16(14)17(8-13)22-2;1-4-26-12-15(9-23-26)28-20-19(21)22-10-17(24-20)13-7-14-11-25(2)6-5-16(14)18(8-13)27-3/h7-10,13,15H,3-6,11-12H2,1-2H3,(H2,23,24);2,4,6-9H,3,5,10-11H2,1H3,(H2,25,27)(H2,26,28);7-10,12-13H,5-6,11H2,1-4H3,(H2,22,23);7-10,12,22H,4-6,11H2,1-3H3,(H2,21,23);7-10,12H,4-6,11H2,1-3H3,(H2,21,22)
InChIKeyMSWCHOWIKXWHRF-UHFFFAOYSA-N
XLogP15.80
TPSA452.80 Ų
H-Bond Donors7
H-Bond Acceptors37
Rotatable Bonds23
Heavy Atoms144
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5001959.32
LogP ≤ 515.80
H-Bond Donors ≤ 57
H-Bond Acceptors ≤ 1037

Analyze 7-[5-amino-6-(1-ethylpyrazol-4-yl)oxypyrazin-2-yl]-N,2-dimethyl-3,4-dihydro-1H-isoquinolin-5-amine;3-[(2-amino-4-pyridinyl)methoxy]-5-[2-methyl-5-(trifluoromethyl)-3,4-dihydro-1H-isoquinolin-7-yl]pyrazin-2-amine;3-[1-(cyclopropylmethyl)pyrazol-4-yl]oxy-5-(2,5-dimethyl-3,4-dihydro-1H-isoquinolin-7-yl)pyrazin-2-amine;5-(2,5-dimethyl-3,4-dihydro-1H-isoquinolin-7-yl)-3-(1-propan-2-ylpyrazol-4-yl)oxypyrazin-2-amine;3-(1-ethylpyrazol-4-yl)oxy-5-(5-methoxy-2-methyl-3,4-dihydro-1H-isoquinolin-7-yl)pyrazin-2-amine with MolForge

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Related Compounds

US20240150366, Example 13
CID 164875478
US20240150366, Example 19
CID 164875486
US20240150366, Example 9
CID 164875490
US20240150366, Example 8
CID 171918776
US20240150366, Example 10
CID 171918777
US20240150366, Example 11
CID 171918778
US20240150366, Example 20
CID 171918780
2-[6-[[[2-[2-Amino-8-(1,1-difluoroethoxy)quinazolin-4-yl]-2-hydrazinylideneethylidene]amino]methyl]-2-pyridinyl]propan-2-ol;2-[6-[[4-(2-amino-7-methylquinazolin-4-yl)triazol-1-yl]methyl]-2-pyridinyl]propan-2-ol;tris(2-[6-[[4-(2-amino-8-methylquinazolin-4-yl)triazol-1-yl]methyl]-2-pyridinyl]propan-2-ol);2-[6-[[[2-(2-aminoquinazolin-4-yl)-2-hydrazinylideneethylidene]amino]methyl]-2-pyridinyl]propan-2-ol
CID 157054160
N,N-diethyl-3-propan-2-ylpyridin-2-amine;2-(3,3-difluoropyrrolidin-1-yl)-3-propan-2-ylpyridine;2-(3-fluoropyrrolidin-1-yl)-3-propan-2-ylpyridine;1-[1-(4-methylphenyl)propyl]-4-propan-2-yltriazole;5-[(2-methylpropan-2-yl)oxy]-2-propan-2-ylpyridine;3-methyl-5-propan-2-yl-2-propan-2-yloxypyridine;4-methyl-2-propan-2-yl-5-propan-2-yloxypyridine;N-(2-methylpropyl)-3-propan-2-ylpyridin-2-amine;2-phenoxy-3-propan-2-ylpyridine;5-phenyl-2-propan-2-ylpyridine;2-piperidin-1-yl-3-propan-2-ylpyridine;5-propan-2-yl-2-propan-2-yloxypyridine;1-(3-propan-2-yl-2-pyridinyl)pyrrolidin-3-ol
CID 157544550
cis-(1S,2R)-2-[[2-amino-7-(2H-pyrrol-3-yl)quinolin-4-yl]amino]cyclohexan-1-ol;4-N-(2,2-difluoro-2-pyridin-2-ylethyl)-7-(2H-pyrrol-3-yl)quinoline-2,4-diamine;4-N-(oxolan-3-yl)-7-(2H-pyrrol-3-yl)quinoline-2,4-diamine;7-(1H-pyrazol-5-yl)-4-(1H-pyrazol-5-ylmethoxy)quinolin-2-amine;7-(1H-pyrazol-5-yl)-4-N-[[(2R)-pyrrolidin-2-yl]methyl]quinoline-2,4-diamine;4-N-(pyridin-3-ylmethyl)-7-(2H-pyrrol-3-yl)quinoline-2,4-diamine
CID 158180195
4-N-(2,2-difluoro-2-pyridin-2-ylethyl)-7-(2H-pyrrol-3-yl)quinoline-2,4-diamine;7-(1H-pyrazol-5-yl)-4-(1H-pyrazol-5-ylmethoxy)quinolin-2-amine;7-(1H-pyrazol-5-yl)-4-N-[[(2R)-pyrrolidin-2-yl]methyl]quinoline-2,4-diamine;4-N-(pyridin-2-ylmethyl)-7-(2H-pyrrol-3-yl)quinoline-2,4-diamine;4-N-(pyridin-3-ylmethyl)-7-(2H-pyrrol-3-yl)quinoline-2,4-diamine
CID 158860377
N-(3-cyclohexyl-1-propan-2-ylpyrazol-5-yl)-8-(4-fluoro-2-methoxyphenyl)quinazolin-2-amine;8-(4-fluoro-2-methoxyphenyl)-N-(4-piperidin-4-yl-2,3-dihydro-1-benzofuran-7-yl)quinazolin-2-amine;8-(5-fluoro-2-methoxyphenyl)-N-(4-piperidin-4-yl-2,3-dihydro-1-benzofuran-7-yl)quinazolin-2-amine;8-[2-methoxy-4-(trifluoromethyl)phenyl]-N-(4-piperidin-4-yl-2,3-dihydro-1-benzofuran-7-yl)quinazolin-2-amine
CID 159319998

Frequently Asked Questions

What is the IUPAC name of 7-[5-amino-6-(1-ethylpyrazol-4-yl)oxypyrazin-2-yl]-N,2-dimethyl-3,4-dihydro-1H-isoquinolin-5-amine;3-[(2-amino-4-pyridinyl)methoxy]-5-[2-methyl-5-(trifluoromethyl)-3,4-dihydro-1H-isoquinolin-7-yl]pyrazin-2-amine;3-[1-(cyclopropylmethyl)pyrazol-4-yl]oxy-5-(2,5-dimethyl-3,4-dihydro-1H-isoquinolin-7-yl)pyrazin-2-amine;5-(2,5-dimethyl-3,4-dihydro-1H-isoquinolin-7-yl)-3-(1-propan-2-ylpyrazol-4-yl)oxypyrazin-2-amine;3-(1-ethylpyrazol-4-yl)oxy-5-(5-methoxy-2-methyl-3,4-dihydro-1H-isoquinolin-7-yl)pyrazin-2-amine?
The IUPAC name of 7-[5-amino-6-(1-ethylpyrazol-4-yl)oxypyrazin-2-yl]-N,2-dimethyl-3,4-dihydro-1H-isoquinolin-5-amine;3-[(2-amino-4-pyridinyl)methoxy]-5-[2-methyl-5-(trifluoromethyl)-3,4-dihydro-1H-isoquinolin-7-yl]pyrazin-2-amine;3-[1-(cyclopropylmethyl)pyrazol-4-yl]oxy-5-(2,5-dimethyl-3,4-dihydro-1H-isoquinolin-7-yl)pyrazin-2-amine;5-(2,5-dimethyl-3,4-dihydro-1H-isoquinolin-7-yl)-3-(1-propan-2-ylpyrazol-4-yl)oxypyrazin-2-amine;3-(1-ethylpyrazol-4-yl)oxy-5-(5-methoxy-2-methyl-3,4-dihydro-1H-isoquinolin-7-yl)pyrazin-2-amine (CID 167623280) is 7-[5-amino-6-(1-ethylpyrazol-4-yl)oxypyrazin-2-yl]-N,2-dimethyl-3,4-dihydro-1H-isoquinolin-5-amine;3-[(2-amino-4-pyridinyl)methoxy]-5-[2-methyl-5-(trifluoromethyl)-3,4-dihydro-1H-isoquinolin-7-yl]pyrazin-2-amine;3-[1-(cyclopropylmethyl)pyrazol-4-yl]oxy-5-(2,5-dimethyl-3,4-dihydro-1H-isoquinolin-7-yl)pyrazin-2-amine;5-(2,5-dimethyl-3,4-dihydro-1H-isoquinolin-7-yl)-3-(1-propan-2-ylpyrazol-4-yl)oxypyrazin-2-amine;3-(1-ethylpyrazol-4-yl)oxy-5-(5-methoxy-2-methyl-3,4-dihydro-1H-isoquinolin-7-yl)pyrazin-2-amine.
What is the SMILES notation for 7-[5-amino-6-(1-ethylpyrazol-4-yl)oxypyrazin-2-yl]-N,2-dimethyl-3,4-dihydro-1H-isoquinolin-5-amine;3-[(2-amino-4-pyridinyl)methoxy]-5-[2-methyl-5-(trifluoromethyl)-3,4-dihydro-1H-isoquinolin-7-yl]pyrazin-2-amine;3-[1-(cyclopropylmethyl)pyrazol-4-yl]oxy-5-(2,5-dimethyl-3,4-dihydro-1H-isoquinolin-7-yl)pyrazin-2-amine;5-(2,5-dimethyl-3,4-dihydro-1H-isoquinolin-7-yl)-3-(1-propan-2-ylpyrazol-4-yl)oxypyrazin-2-amine;3-(1-ethylpyrazol-4-yl)oxy-5-(5-methoxy-2-methyl-3,4-dihydro-1H-isoquinolin-7-yl)pyrazin-2-amine?
The canonical SMILES for 7-[5-amino-6-(1-ethylpyrazol-4-yl)oxypyrazin-2-yl]-N,2-dimethyl-3,4-dihydro-1H-isoquinolin-5-amine;3-[(2-amino-4-pyridinyl)methoxy]-5-[2-methyl-5-(trifluoromethyl)-3,4-dihydro-1H-isoquinolin-7-yl]pyrazin-2-amine;3-[1-(cyclopropylmethyl)pyrazol-4-yl]oxy-5-(2,5-dimethyl-3,4-dihydro-1H-isoquinolin-7-yl)pyrazin-2-amine;5-(2,5-dimethyl-3,4-dihydro-1H-isoquinolin-7-yl)-3-(1-propan-2-ylpyrazol-4-yl)oxypyrazin-2-amine;3-(1-ethylpyrazol-4-yl)oxy-5-(5-methoxy-2-methyl-3,4-dihydro-1H-isoquinolin-7-yl)pyrazin-2-amine is CCn1cc(Oc2nc(-c3cc4c(c(NC)c3)CCN(C)C4)cnc2N)cn1.CCn1cc(Oc2nc(-c3cc4c(c(OC)c3)CCN(C)C4)cnc2N)cn1.CN1CCc2c(cc(-c3cnc(N)c(OCc4ccnc(N)c4)n3)cc2C(F)(F)F)C1.Cc1cc(-c2cnc(N)c(Oc3cnn(C(C)C)c3)n2)cc2c1CCN(C)C2.Cc1cc(-c2cnc(N)c(Oc3cnn(CC4CC4)c3)n2)cc2c1CCN(C)C2.
What is the InChIKey of 7-[5-amino-6-(1-ethylpyrazol-4-yl)oxypyrazin-2-yl]-N,2-dimethyl-3,4-dihydro-1H-isoquinolin-5-amine;3-[(2-amino-4-pyridinyl)methoxy]-5-[2-methyl-5-(trifluoromethyl)-3,4-dihydro-1H-isoquinolin-7-yl]pyrazin-2-amine;3-[1-(cyclopropylmethyl)pyrazol-4-yl]oxy-5-(2,5-dimethyl-3,4-dihydro-1H-isoquinolin-7-yl)pyrazin-2-amine;5-(2,5-dimethyl-3,4-dihydro-1H-isoquinolin-7-yl)-3-(1-propan-2-ylpyrazol-4-yl)oxypyrazin-2-amine;3-(1-ethylpyrazol-4-yl)oxy-5-(5-methoxy-2-methyl-3,4-dihydro-1H-isoquinolin-7-yl)pyrazin-2-amine?
The InChIKey is MSWCHOWIKXWHRF-UHFFFAOYSA-N. The full InChI is InChI=1S/C22H26N6O.C21H21F3N6O.C21H26N6O.C20H25N7O.C20H24N6O2/c1-14-7-16(8-17-12-27(2)6-5-19(14)17)20-10-24-21(23)22(26-20)29-18-9-25-28(13-18)11-15-3-4-15;1-30-5-3-15-14(10-30)7-13(8-16(15)21(22,23)24)17-9-28-19(26)20(29-17)31-11-12-2-4-27-18(25)6-12;1-13(2)27-12-17(9-24-27)28-21-20(22)23-10-19(25-21)15-7-14(3)18-5-6-26(4)11-16(18)8-15;1-4-27-12-15(9-24-27)28-20-19(21)23-10-18(25-20)13-7-14-11-26(3)6-5-16(14)17(8-13)22-2;1-4-26-12-15(9-23-26)28-20-19(21)22-10-17(24-20)13-7-14-11-25(2)6-5-16(14)18(8-13)27-3/h7-10,13,15H,3-6,11-12H2,1-2H3,(H2,23,24);2,4,6-9H,3,5,10-11H2,1H3,(H2,25,27)(H2,26,28);7-10,12-13H,5-6,11H2,1-4H3,(H2,22,23);7-10,12,22H,4-6,11H2,1-3H3,(H2,21,23);7-10,12H,4-6,11H2,1-3H3,(H2,21,22).
What are the key properties of 7-[5-amino-6-(1-ethylpyrazol-4-yl)oxypyrazin-2-yl]-N,2-dimethyl-3,4-dihydro-1H-isoquinolin-5-amine;3-[(2-amino-4-pyridinyl)methoxy]-5-[2-methyl-5-(trifluoromethyl)-3,4-dihydro-1H-isoquinolin-7-yl]pyrazin-2-amine;3-[1-(cyclopropylmethyl)pyrazol-4-yl]oxy-5-(2,5-dimethyl-3,4-dihydro-1H-isoquinolin-7-yl)pyrazin-2-amine;5-(2,5-dimethyl-3,4-dihydro-1H-isoquinolin-7-yl)-3-(1-propan-2-ylpyrazol-4-yl)oxypyrazin-2-amine;3-(1-ethylpyrazol-4-yl)oxy-5-(5-methoxy-2-methyl-3,4-dihydro-1H-isoquinolin-7-yl)pyrazin-2-amine?
7-[5-amino-6-(1-ethylpyrazol-4-yl)oxypyrazin-2-yl]-N,2-dimethyl-3,4-dihydro-1H-isoquinolin-5-amine;3-[(2-amino-4-pyridinyl)methoxy]-5-[2-methyl-5-(trifluoromethyl)-3,4-dihydro-1H-isoquinolin-7-yl]pyrazin-2-amine;3-[1-(cyclopropylmethyl)pyrazol-4-yl]oxy-5-(2,5-dimethyl-3,4-dihydro-1H-isoquinolin-7-yl)pyrazin-2-amine;5-(2,5-dimethyl-3,4-dihydro-1H-isoquinolin-7-yl)-3-(1-propan-2-ylpyrazol-4-yl)oxypyrazin-2-amine;3-(1-ethylpyrazol-4-yl)oxy-5-(5-methoxy-2-methyl-3,4-dihydro-1H-isoquinolin-7-yl)pyrazin-2-amine has a molecular weight of 1959.32 g/mol, XLogP of 15.80, 23 rotatable bonds, 7 hydrogen bond donors, and 37 hydrogen bond acceptors.
Where does this data come from?
All data for 7-[5-amino-6-(1-ethylpyrazol-4-yl)oxypyrazin-2-yl]-N,2-dimethyl-3,4-dihydro-1H-isoquinolin-5-amine;3-[(2-amino-4-pyridinyl)methoxy]-5-[2-methyl-5-(trifluoromethyl)-3,4-dihydro-1H-isoquinolin-7-yl]pyrazin-2-amine;3-[1-(cyclopropylmethyl)pyrazol-4-yl]oxy-5-(2,5-dimethyl-3,4-dihydro-1H-isoquinolin-7-yl)pyrazin-2-amine;5-(2,5-dimethyl-3,4-dihydro-1H-isoquinolin-7-yl)-3-(1-propan-2-ylpyrazol-4-yl)oxypyrazin-2-amine;3-(1-ethylpyrazol-4-yl)oxy-5-(5-methoxy-2-methyl-3,4-dihydro-1H-isoquinolin-7-yl)pyrazin-2-amine is sourced from PubChem (CID 167623280), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).