6-chloro-N-[(3R)-7-piperazin-1-yl-3,4-dihydro-2H-chromen-3-yl]indolizine-1-carboxamide;5,7-dimethyl-N-[(3R)-7-piperazin-1-yl-3,4-dihydro-2H-chromen-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;6-methyl-N-[(3R)-7-piperazin-1-yl-3,4-dihydro-2H-chromen-3-yl]imidazo[1,2-b]pyridazine-2-carboxamide;7-methyl-N-[(3R)-7-piperazin-1-yl-3,4-dihydro-2H-chromen-3-yl]indolizine-1-carboxamide

C88H99ClN20O8 — CID 167641066

About 6-chloro-N-[(3R)-7-piperazin-1-yl-3,4-dihydro-2H-chromen-3-yl]indolizine-1-carboxamide;5,7-dimethyl-N-[(3R)-7-piperazin-1-yl-3,4-dihydro-2H-chromen-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;6-methyl-N-[(3R)-7-piperazin-1-yl-3,4-dihydro-2H-chromen-3-yl]imidazo[1,2-b]pyridazine-2-carboxamide;7-methyl-N-[(3R)-7-piperazin-1-yl-3,4-dihydro-2H-chromen-3-yl]indolizine-1-carboxamide

6-chloro-N-[(3R)-7-piperazin-1-yl-3,4-dihydro-2H-chromen-3-yl]indolizine-1-carboxamide;5,7-dimethyl-N-[(3R)-7-piperazin-1-yl-3,4-dihydro-2H-chromen-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;6-methyl-N-[(3R)-7-piperazin-1-yl-3,4-dihydro-2H-chromen-3-yl]imidazo[1,2-b]pyridazine-2-carboxamide;7-methyl-N-[(3R)-7-piperazin-1-yl-3,4-dihydro-2H-chromen-3-yl]indolizine-1-carboxamide (PubChem CID 167641066) has the molecular formula C88H99ClN20O8 and a molecular weight of 1600.34 g/mol. Its IUPAC name is 6-chloro-N-[(3R)-7-piperazin-1-yl-3,4-dihydro-2H-chromen-3-yl]indolizine-1-carboxamide;5,7-dimethyl-N-[(3R)-7-piperazin-1-yl-3,4-dihydro-2H-chromen-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;6-methyl-N-[(3R)-7-piperazin-1-yl-3,4-dihydro-2H-chromen-3-yl]imidazo[1,2-b]pyridazine-2-carboxamide;7-methyl-N-[(3R)-7-piperazin-1-yl-3,4-dihydro-2H-chromen-3-yl]indolizine-1-carboxamide.

Molecular Properties

• Compound Name: 6-chloro-N-[(3R)-7-piperazin-1-yl-3,4-dihydro-2H-chromen-3-yl]indolizine-1-carboxamide;5,7-dimethyl-N-[(3R)-7-piperazin-1-yl-3,4-dihydro-2H-chromen-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;6-methyl-N-[(3R)-7-piperazin-1-yl-3,4-dihydro-2H-chromen-3-yl]imidazo[1,2-b]pyridazine-2-carboxamide;7-methyl-N-[(3R)-7-piperazin-1-yl-3,4-dihydro-2H-chromen-3-yl]indolizine-1-carboxamide
• PubChem CID: 167641066
• Molecular Formula: C88H99ClN20O8
• Molecular Weight: 1600.34 g/mol
• Exact Mass: 1598.76
• IUPAC Name: 6-chloro-N-[(3R)-7-piperazin-1-yl-3,4-dihydro-2H-chromen-3-yl]indolizine-1-carboxamide;5,7-dimethyl-N-[(3R)-7-piperazin-1-yl-3,4-dihydro-2H-chromen-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;6-methyl-N-[(3R)-7-piperazin-1-yl-3,4-dihydro-2H-chromen-3-yl]imidazo[1,2-b]pyridazine-2-carboxamide;7-methyl-N-[(3R)-7-piperazin-1-yl-3,4-dihydro-2H-chromen-3-yl]indolizine-1-carboxamide
• SMILES: Cc1cc(C)n2ncc(C(=O)N[C@H]3COc4cc(N5CCNCC5)ccc4C3)c2n1.Cc1ccc2nc(C(=O)N[C@H]3COc4cc(N5CCNCC5)ccc4C3)cn2n1.Cc1ccn2ccc(C(=O)N[C@H]3COc4cc(N5CCNCC5)ccc4C3)c2c1.O=C(N[C@H]1COc2cc(N3CCNCC3)ccc2C1)c1ccn2cc(Cl)ccc12
• InChI: InChI=1S/C23H26N4O2.C22H23ClN4O2.C22H26N6O2.C21H24N6O2/c1-16-4-8-27-9-5-20(21(27)12-16)23(28)25-18-13-17-2-3-19(14-22(17)29-15-18)26-10-6-24-7-11-26;23-16-2-4-20-19(5-8-27(20)13-16)22(28)25-17-11-15-1-3-18(12-21(15)29-14-17)26-9-6-24-7-10-26;1-14-9-15(2)28-21(25-14)19(12-24-28)22(29)26-17-10-16-3-4-18(11-20(16)30-13-17)27-7-5-23-6-8-27;1-14-2-5-20-24-18(12-27(20)25-14)21(28)23-16-10-15-3-4-17(11-19(15)29-13-16)26-8-6-22-7-9-26/h2-5,8-9,12,14,18,24H,6-7,10-11,13,15H2,1H3,(H,25,28);1-5,8,12-13,17,24H,6-7,9-11,14H2,(H,25,28);3-4,9,11-12,17,23H,5-8,10,13H2,1-2H3,(H,26,29);2-5,11-12,16,22H,6-10,13H2,1H3,(H,23,28)/t18-;2*17-;16-/m1111/s1
• InChIKey: PEAKDJAQNIQKJN-RYBCAFGYSA-N
• XLogP: 7.80
• TPSA: 283.60 Ų
• H-Bond Donors: 8
• H-Bond Acceptors: 24
• Rotatable Bonds: 12
• Heavy Atoms: 117
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	1600.34
LogP ≤ 5	7.80
H-Bond Donors ≤ 5	8
H-Bond Acceptors ≤ 10	24

Frequently Asked Questions

What is the IUPAC name of 6-chloro-N-[(3R)-7-piperazin-1-yl-3,4-dihydro-2H-chromen-3-yl]indolizine-1-carboxamide;5,7-dimethyl-N-[(3R)-7-piperazin-1-yl-3,4-dihydro-2H-chromen-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;6-methyl-N-[(3R)-7-piperazin-1-yl-3,4-dihydro-2H-chromen-3-yl]imidazo[1,2-b]pyridazine-2-carboxamide;7-methyl-N-[(3R)-7-piperazin-1-yl-3,4-dihydro-2H-chromen-3-yl]indolizine-1-carboxamide?

The IUPAC name of 6-chloro-N-[(3R)-7-piperazin-1-yl-3,4-dihydro-2H-chromen-3-yl]indolizine-1-carboxamide;5,7-dimethyl-N-[(3R)-7-piperazin-1-yl-3,4-dihydro-2H-chromen-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;6-methyl-N-[(3R)-7-piperazin-1-yl-3,4-dihydro-2H-chromen-3-yl]imidazo[1,2-b]pyridazine-2-carboxamide;7-methyl-N-[(3R)-7-piperazin-1-yl-3,4-dihydro-2H-chromen-3-yl]indolizine-1-carboxamide (CID 167641066) is 6-chloro-N-[(3R)-7-piperazin-1-yl-3,4-dihydro-2H-chromen-3-yl]indolizine-1-carboxamide;5,7-dimethyl-N-[(3R)-7-piperazin-1-yl-3,4-dihydro-2H-chromen-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;6-methyl-N-[(3R)-7-piperazin-1-yl-3,4-dihydro-2H-chromen-3-yl]imidazo[1,2-b]pyridazine-2-carboxamide;7-methyl-N-[(3R)-7-piperazin-1-yl-3,4-dihydro-2H-chromen-3-yl]indolizine-1-carboxamide.

What is the SMILES notation for 6-chloro-N-[(3R)-7-piperazin-1-yl-3,4-dihydro-2H-chromen-3-yl]indolizine-1-carboxamide;5,7-dimethyl-N-[(3R)-7-piperazin-1-yl-3,4-dihydro-2H-chromen-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;6-methyl-N-[(3R)-7-piperazin-1-yl-3,4-dihydro-2H-chromen-3-yl]imidazo[1,2-b]pyridazine-2-carboxamide;7-methyl-N-[(3R)-7-piperazin-1-yl-3,4-dihydro-2H-chromen-3-yl]indolizine-1-carboxamide?

The canonical SMILES for 6-chloro-N-[(3R)-7-piperazin-1-yl-3,4-dihydro-2H-chromen-3-yl]indolizine-1-carboxamide;5,7-dimethyl-N-[(3R)-7-piperazin-1-yl-3,4-dihydro-2H-chromen-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;6-methyl-N-[(3R)-7-piperazin-1-yl-3,4-dihydro-2H-chromen-3-yl]imidazo[1,2-b]pyridazine-2-carboxamide;7-methyl-N-[(3R)-7-piperazin-1-yl-3,4-dihydro-2H-chromen-3-yl]indolizine-1-carboxamide is Cc1cc(C)n2ncc(C(=O)N[C@H]3COc4cc(N5CCNCC5)ccc4C3)c2n1.Cc1ccc2nc(C(=O)N[C@H]3COc4cc(N5CCNCC5)ccc4C3)cn2n1.Cc1ccn2ccc(C(=O)N[C@H]3COc4cc(N5CCNCC5)ccc4C3)c2c1.O=C(N[C@H]1COc2cc(N3CCNCC3)ccc2C1)c1ccn2cc(Cl)ccc12.

What is the InChIKey of 6-chloro-N-[(3R)-7-piperazin-1-yl-3,4-dihydro-2H-chromen-3-yl]indolizine-1-carboxamide;5,7-dimethyl-N-[(3R)-7-piperazin-1-yl-3,4-dihydro-2H-chromen-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;6-methyl-N-[(3R)-7-piperazin-1-yl-3,4-dihydro-2H-chromen-3-yl]imidazo[1,2-b]pyridazine-2-carboxamide;7-methyl-N-[(3R)-7-piperazin-1-yl-3,4-dihydro-2H-chromen-3-yl]indolizine-1-carboxamide?

The InChIKey is PEAKDJAQNIQKJN-RYBCAFGYSA-N. The full InChI is InChI=1S/C23H26N4O2.C22H23ClN4O2.C22H26N6O2.C21H24N6O2/c1-16-4-8-27-9-5-20(21(27)12-16)23(28)25-18-13-17-2-3-19(14-22(17)29-15-18)26-10-6-24-7-11-26;23-16-2-4-20-19(5-8-27(20)13-16)22(28)25-17-11-15-1-3-18(12-21(15)29-14-17)26-9-6-24-7-10-26;1-14-9-15(2)28-21(25-14)19(12-24-28)22(29)26-17-10-16-3-4-18(11-20(16)30-13-17)27-7-5-23-6-8-27;1-14-2-5-20-24-18(12-27(20)25-14)21(28)23-16-10-15-3-4-17(11-19(15)29-13-16)26-8-6-22-7-9-26/h2-5,8-9,12,14,18,24H,6-7,10-11,13,15H2,1H3,(H,25,28);1-5,8,12-13,17,24H,6-7,9-11,14H2,(H,25,28);3-4,9,11-12,17,23H,5-8,10,13H2,1-2H3,(H,26,29);2-5,11-12,16,22H,6-10,13H2,1H3,(H,23,28)/t18-;2*17-;16-/m1111/s1.

What are the key properties of 6-chloro-N-[(3R)-7-piperazin-1-yl-3,4-dihydro-2H-chromen-3-yl]indolizine-1-carboxamide;5,7-dimethyl-N-[(3R)-7-piperazin-1-yl-3,4-dihydro-2H-chromen-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;6-methyl-N-[(3R)-7-piperazin-1-yl-3,4-dihydro-2H-chromen-3-yl]imidazo[1,2-b]pyridazine-2-carboxamide;7-methyl-N-[(3R)-7-piperazin-1-yl-3,4-dihydro-2H-chromen-3-yl]indolizine-1-carboxamide?

6-chloro-N-[(3R)-7-piperazin-1-yl-3,4-dihydro-2H-chromen-3-yl]indolizine-1-carboxamide;5,7-dimethyl-N-[(3R)-7-piperazin-1-yl-3,4-dihydro-2H-chromen-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;6-methyl-N-[(3R)-7-piperazin-1-yl-3,4-dihydro-2H-chromen-3-yl]imidazo[1,2-b]pyridazine-2-carboxamide;7-methyl-N-[(3R)-7-piperazin-1-yl-3,4-dihydro-2H-chromen-3-yl]indolizine-1-carboxamide has a molecular weight of 1600.34 g/mol, XLogP of 7.80, 12 rotatable bonds, 8 hydrogen bond donors, and 24 hydrogen bond acceptors.

Where does this data come from?

All data for 6-chloro-N-[(3R)-7-piperazin-1-yl-3,4-dihydro-2H-chromen-3-yl]indolizine-1-carboxamide;5,7-dimethyl-N-[(3R)-7-piperazin-1-yl-3,4-dihydro-2H-chromen-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;6-methyl-N-[(3R)-7-piperazin-1-yl-3,4-dihydro-2H-chromen-3-yl]imidazo[1,2-b]pyridazine-2-carboxamide;7-methyl-N-[(3R)-7-piperazin-1-yl-3,4-dihydro-2H-chromen-3-yl]indolizine-1-carboxamide is sourced from PubChem (CID 167641066), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).