6-cyclopropyloxy-N-[4-[1-ethyl-6-(1H-pyrazol-4-yl)indazol-5-yl]oxy-3-fluorophenyl]-1-(4-fluorophenyl)-2-oxopyridine-3-carboxamide;N-[4-[1-ethyl-6-(1H-pyrazol-4-yl)indazol-5-yl]oxy-3-fluorophenyl]-1-(4-fluorophenyl)-2-oxo-6-propan-2-yloxypyridine-3-carboxamide;N-[4-[1-ethyl-6-(1H-pyrazol-4-yl)indazol-5-yl]oxy-3-fluorophenyl]-1-(4-fluorophenyl)-2-oxo-6-(2,2,2-trifluoroethoxy)pyridine-3-carboxamide

C98H77F9N18O12 — CID 167641682

IUPAC6-cyclopropyloxy-N-[4-[1-ethyl-6-(1H-pyrazol-4-yl)indazol-5-yl]oxy-3-fluorophenyl]-1-(4-fluorophenyl)-2-oxopyridine-3-carboxamide;N-[4-[1-ethyl-6-(1H-pyrazol-4-yl)indazol-5-yl]oxy-3-fluorophenyl]-1-(4-fluorophenyl)-2-oxo-6-propan-2-yloxypyridine-3-carboxamide;N-[4-[1-ethyl-6-(1H-pyrazol-4-yl)indazol-5-yl]oxy-3-fluorophenyl]-1-(4-fluorophenyl)-2-oxo-6-(2,2,2-trifluoroethoxy)pyridine-3-carboxamide
SMILESCCn1ncc2cc(Oc3ccc(NC(=O)c4ccc(OC(C)C)n(-c5ccc(F)cc5)c4=O)cc3F)c(-c3cn[nH]c3)cc21.CCn1ncc2cc(Oc3ccc(NC(=O)c4ccc(OC5CC5)n(-c5ccc(F)cc5)c4=O)cc3F)c(-c3cn[nH]c3)cc21.CCn1ncc2cc(Oc3ccc(NC(=O)c4ccc(OCC(F)(F)F)n(-c5ccc(F)cc5)c4=O)cc3F)c(-c3cn[nH]c3)cc21
InChIInChI=1S/C33H26F2N6O4.C33H28F2N6O4.C32H23F5N6O4/c1-2-40-28-15-26(20-16-36-37-17-20)30(13-19(28)18-38-40)45-29-11-5-22(14-27(29)35)39-32(42)25-10-12-31(44-24-8-9-24)41(33(25)43)23-6-3-21(34)4-7-23;1-4-40-28-15-26(21-16-36-37-17-21)30(13-20(28)18-38-40)45-29-11-7-23(14-27(29)35)39-32(42)25-10-12-31(44-19(2)3)41(33(25)43)24-8-5-22(34)6-9-24;1-2-42-26-13-24(19-14-38-39-15-19)28(11-18(26)16-40-42)47-27-9-5-21(12-25(27)34)41-30(44)23-8-10-29(46-17-32(35,36)37)43(31(23)45)22-6-3-20(33)4-7-22/h3-7,10-18,24H,2,8-9H2,1H3,(H,36,37)(H,39,42);5-19H,4H2,1-3H3,(H,36,37)(H,39,42);3-16H,2,17H2,1H3,(H,38,39)(H,41,44)
InChIKeyPGBUSPASFSUPGH-UHFFFAOYSA-N
MW1869.79 g/mol
LogP20.03
Rot. Bonds27

About 6-cyclopropyloxy-N-[4-[1-ethyl-6-(1H-pyrazol-4-yl)indazol-5-yl]oxy-3-fluorophenyl]-1-(4-fluorophenyl)-2-oxopyridine-3-carboxamide;N-[4-[1-ethyl-6-(1H-pyrazol-4-yl)indazol-5-yl]oxy-3-fluorophenyl]-1-(4-fluorophenyl)-2-oxo-6-propan-2-yloxypyridine-3-carboxamide;N-[4-[1-ethyl-6-(1H-pyrazol-4-yl)indazol-5-yl]oxy-3-fluorophenyl]-1-(4-fluorophenyl)-2-oxo-6-(2,2,2-trifluoroethoxy)pyridine-3-carboxamide

6-cyclopropyloxy-N-[4-[1-ethyl-6-(1H-pyrazol-4-yl)indazol-5-yl]oxy-3-fluorophenyl]-1-(4-fluorophenyl)-2-oxopyridine-3-carboxamide;N-[4-[1-ethyl-6-(1H-pyrazol-4-yl)indazol-5-yl]oxy-3-fluorophenyl]-1-(4-fluorophenyl)-2-oxo-6-propan-2-yloxypyridine-3-carboxamide;N-[4-[1-ethyl-6-(1H-pyrazol-4-yl)indazol-5-yl]oxy-3-fluorophenyl]-1-(4-fluorophenyl)-2-oxo-6-(2,2,2-trifluoroethoxy)pyridine-3-carboxamide (PubChem CID 167641682) has the molecular formula C98H77F9N18O12 and a molecular weight of 1869.79 g/mol. Its IUPAC name is 6-cyclopropyloxy-N-[4-[1-ethyl-6-(1H-pyrazol-4-yl)indazol-5-yl]oxy-3-fluorophenyl]-1-(4-fluorophenyl)-2-oxopyridine-3-carboxamide;N-[4-[1-ethyl-6-(1H-pyrazol-4-yl)indazol-5-yl]oxy-3-fluorophenyl]-1-(4-fluorophenyl)-2-oxo-6-propan-2-yloxypyridine-3-carboxamide;N-[4-[1-ethyl-6-(1H-pyrazol-4-yl)indazol-5-yl]oxy-3-fluorophenyl]-1-(4-fluorophenyl)-2-oxo-6-(2,2,2-trifluoroethoxy)pyridine-3-carboxamide.

Molecular Properties

Compound Name6-cyclopropyloxy-N-[4-[1-ethyl-6-(1H-pyrazol-4-yl)indazol-5-yl]oxy-3-fluorophenyl]-1-(4-fluorophenyl)-2-oxopyridine-3-carboxamide;N-[4-[1-ethyl-6-(1H-pyrazol-4-yl)indazol-5-yl]oxy-3-fluorophenyl]-1-(4-fluorophenyl)-2-oxo-6-propan-2-yloxypyridine-3-carboxamide;N-[4-[1-ethyl-6-(1H-pyrazol-4-yl)indazol-5-yl]oxy-3-fluorophenyl]-1-(4-fluorophenyl)-2-oxo-6-(2,2,2-trifluoroethoxy)pyridine-3-carboxamide
PubChem CID167641682
Molecular FormulaC98H77F9N18O12
Molecular Weight1869.79 g/mol
Exact Mass1868.58
IUPAC Name6-cyclopropyloxy-N-[4-[1-ethyl-6-(1H-pyrazol-4-yl)indazol-5-yl]oxy-3-fluorophenyl]-1-(4-fluorophenyl)-2-oxopyridine-3-carboxamide;N-[4-[1-ethyl-6-(1H-pyrazol-4-yl)indazol-5-yl]oxy-3-fluorophenyl]-1-(4-fluorophenyl)-2-oxo-6-propan-2-yloxypyridine-3-carboxamide;N-[4-[1-ethyl-6-(1H-pyrazol-4-yl)indazol-5-yl]oxy-3-fluorophenyl]-1-(4-fluorophenyl)-2-oxo-6-(2,2,2-trifluoroethoxy)pyridine-3-carboxamide
SMILESCCn1ncc2cc(Oc3ccc(NC(=O)c4ccc(OC(C)C)n(-c5ccc(F)cc5)c4=O)cc3F)c(-c3cn[nH]c3)cc21.CCn1ncc2cc(Oc3ccc(NC(=O)c4ccc(OC5CC5)n(-c5ccc(F)cc5)c4=O)cc3F)c(-c3cn[nH]c3)cc21.CCn1ncc2cc(Oc3ccc(NC(=O)c4ccc(OCC(F)(F)F)n(-c5ccc(F)cc5)c4=O)cc3F)c(-c3cn[nH]c3)cc21
InChIInChI=1S/C33H26F2N6O4.C33H28F2N6O4.C32H23F5N6O4/c1-2-40-28-15-26(20-16-36-37-17-20)30(13-19(28)18-38-40)45-29-11-5-22(14-27(29)35)39-32(42)25-10-12-31(44-24-8-9-24)41(33(25)43)23-6-3-21(34)4-7-23;1-4-40-28-15-26(21-16-36-37-17-21)30(13-20(28)18-38-40)45-29-11-7-23(14-27(29)35)39-32(42)25-10-12-31(44-19(2)3)41(33(25)43)24-8-5-22(34)6-9-24;1-2-42-26-13-24(19-14-38-39-15-19)28(11-18(26)16-40-42)47-27-9-5-21(12-25(27)34)41-30(44)23-8-10-29(46-17-32(35,36)37)43(31(23)45)22-6-3-20(33)4-7-22/h3-7,10-18,24H,2,8-9H2,1H3,(H,36,37)(H,39,42);5-19H,4H2,1-3H3,(H,36,37)(H,39,42);3-16H,2,17H2,1H3,(H,38,39)(H,41,44)
InChIKeyPGBUSPASFSUPGH-UHFFFAOYSA-N
XLogP20.03
TPSA348.18 Ų
H-Bond Donors6
H-Bond Acceptors24
Rotatable Bonds27
Heavy Atoms137
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5001869.79
LogP ≤ 520.03
H-Bond Donors ≤ 56
H-Bond Acceptors ≤ 1024

Analyze 6-cyclopropyloxy-N-[4-[1-ethyl-6-(1H-pyrazol-4-yl)indazol-5-yl]oxy-3-fluorophenyl]-1-(4-fluorophenyl)-2-oxopyridine-3-carboxamide;N-[4-[1-ethyl-6-(1H-pyrazol-4-yl)indazol-5-yl]oxy-3-fluorophenyl]-1-(4-fluorophenyl)-2-oxo-6-propan-2-yloxypyridine-3-carboxamide;N-[4-[1-ethyl-6-(1H-pyrazol-4-yl)indazol-5-yl]oxy-3-fluorophenyl]-1-(4-fluorophenyl)-2-oxo-6-(2,2,2-trifluoroethoxy)pyridine-3-carboxamide with MolForge

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Frequently Asked Questions

What is the IUPAC name of 6-cyclopropyloxy-N-[4-[1-ethyl-6-(1H-pyrazol-4-yl)indazol-5-yl]oxy-3-fluorophenyl]-1-(4-fluorophenyl)-2-oxopyridine-3-carboxamide;N-[4-[1-ethyl-6-(1H-pyrazol-4-yl)indazol-5-yl]oxy-3-fluorophenyl]-1-(4-fluorophenyl)-2-oxo-6-propan-2-yloxypyridine-3-carboxamide;N-[4-[1-ethyl-6-(1H-pyrazol-4-yl)indazol-5-yl]oxy-3-fluorophenyl]-1-(4-fluorophenyl)-2-oxo-6-(2,2,2-trifluoroethoxy)pyridine-3-carboxamide?
The IUPAC name of 6-cyclopropyloxy-N-[4-[1-ethyl-6-(1H-pyrazol-4-yl)indazol-5-yl]oxy-3-fluorophenyl]-1-(4-fluorophenyl)-2-oxopyridine-3-carboxamide;N-[4-[1-ethyl-6-(1H-pyrazol-4-yl)indazol-5-yl]oxy-3-fluorophenyl]-1-(4-fluorophenyl)-2-oxo-6-propan-2-yloxypyridine-3-carboxamide;N-[4-[1-ethyl-6-(1H-pyrazol-4-yl)indazol-5-yl]oxy-3-fluorophenyl]-1-(4-fluorophenyl)-2-oxo-6-(2,2,2-trifluoroethoxy)pyridine-3-carboxamide (CID 167641682) is 6-cyclopropyloxy-N-[4-[1-ethyl-6-(1H-pyrazol-4-yl)indazol-5-yl]oxy-3-fluorophenyl]-1-(4-fluorophenyl)-2-oxopyridine-3-carboxamide;N-[4-[1-ethyl-6-(1H-pyrazol-4-yl)indazol-5-yl]oxy-3-fluorophenyl]-1-(4-fluorophenyl)-2-oxo-6-propan-2-yloxypyridine-3-carboxamide;N-[4-[1-ethyl-6-(1H-pyrazol-4-yl)indazol-5-yl]oxy-3-fluorophenyl]-1-(4-fluorophenyl)-2-oxo-6-(2,2,2-trifluoroethoxy)pyridine-3-carboxamide.
What is the SMILES notation for 6-cyclopropyloxy-N-[4-[1-ethyl-6-(1H-pyrazol-4-yl)indazol-5-yl]oxy-3-fluorophenyl]-1-(4-fluorophenyl)-2-oxopyridine-3-carboxamide;N-[4-[1-ethyl-6-(1H-pyrazol-4-yl)indazol-5-yl]oxy-3-fluorophenyl]-1-(4-fluorophenyl)-2-oxo-6-propan-2-yloxypyridine-3-carboxamide;N-[4-[1-ethyl-6-(1H-pyrazol-4-yl)indazol-5-yl]oxy-3-fluorophenyl]-1-(4-fluorophenyl)-2-oxo-6-(2,2,2-trifluoroethoxy)pyridine-3-carboxamide?
The canonical SMILES for 6-cyclopropyloxy-N-[4-[1-ethyl-6-(1H-pyrazol-4-yl)indazol-5-yl]oxy-3-fluorophenyl]-1-(4-fluorophenyl)-2-oxopyridine-3-carboxamide;N-[4-[1-ethyl-6-(1H-pyrazol-4-yl)indazol-5-yl]oxy-3-fluorophenyl]-1-(4-fluorophenyl)-2-oxo-6-propan-2-yloxypyridine-3-carboxamide;N-[4-[1-ethyl-6-(1H-pyrazol-4-yl)indazol-5-yl]oxy-3-fluorophenyl]-1-(4-fluorophenyl)-2-oxo-6-(2,2,2-trifluoroethoxy)pyridine-3-carboxamide is CCn1ncc2cc(Oc3ccc(NC(=O)c4ccc(OC(C)C)n(-c5ccc(F)cc5)c4=O)cc3F)c(-c3cn[nH]c3)cc21.CCn1ncc2cc(Oc3ccc(NC(=O)c4ccc(OC5CC5)n(-c5ccc(F)cc5)c4=O)cc3F)c(-c3cn[nH]c3)cc21.CCn1ncc2cc(Oc3ccc(NC(=O)c4ccc(OCC(F)(F)F)n(-c5ccc(F)cc5)c4=O)cc3F)c(-c3cn[nH]c3)cc21.
What is the InChIKey of 6-cyclopropyloxy-N-[4-[1-ethyl-6-(1H-pyrazol-4-yl)indazol-5-yl]oxy-3-fluorophenyl]-1-(4-fluorophenyl)-2-oxopyridine-3-carboxamide;N-[4-[1-ethyl-6-(1H-pyrazol-4-yl)indazol-5-yl]oxy-3-fluorophenyl]-1-(4-fluorophenyl)-2-oxo-6-propan-2-yloxypyridine-3-carboxamide;N-[4-[1-ethyl-6-(1H-pyrazol-4-yl)indazol-5-yl]oxy-3-fluorophenyl]-1-(4-fluorophenyl)-2-oxo-6-(2,2,2-trifluoroethoxy)pyridine-3-carboxamide?
The InChIKey is PGBUSPASFSUPGH-UHFFFAOYSA-N. The full InChI is InChI=1S/C33H26F2N6O4.C33H28F2N6O4.C32H23F5N6O4/c1-2-40-28-15-26(20-16-36-37-17-20)30(13-19(28)18-38-40)45-29-11-5-22(14-27(29)35)39-32(42)25-10-12-31(44-24-8-9-24)41(33(25)43)23-6-3-21(34)4-7-23;1-4-40-28-15-26(21-16-36-37-17-21)30(13-20(28)18-38-40)45-29-11-7-23(14-27(29)35)39-32(42)25-10-12-31(44-19(2)3)41(33(25)43)24-8-5-22(34)6-9-24;1-2-42-26-13-24(19-14-38-39-15-19)28(11-18(26)16-40-42)47-27-9-5-21(12-25(27)34)41-30(44)23-8-10-29(46-17-32(35,36)37)43(31(23)45)22-6-3-20(33)4-7-22/h3-7,10-18,24H,2,8-9H2,1H3,(H,36,37)(H,39,42);5-19H,4H2,1-3H3,(H,36,37)(H,39,42);3-16H,2,17H2,1H3,(H,38,39)(H,41,44).
What are the key properties of 6-cyclopropyloxy-N-[4-[1-ethyl-6-(1H-pyrazol-4-yl)indazol-5-yl]oxy-3-fluorophenyl]-1-(4-fluorophenyl)-2-oxopyridine-3-carboxamide;N-[4-[1-ethyl-6-(1H-pyrazol-4-yl)indazol-5-yl]oxy-3-fluorophenyl]-1-(4-fluorophenyl)-2-oxo-6-propan-2-yloxypyridine-3-carboxamide;N-[4-[1-ethyl-6-(1H-pyrazol-4-yl)indazol-5-yl]oxy-3-fluorophenyl]-1-(4-fluorophenyl)-2-oxo-6-(2,2,2-trifluoroethoxy)pyridine-3-carboxamide?
6-cyclopropyloxy-N-[4-[1-ethyl-6-(1H-pyrazol-4-yl)indazol-5-yl]oxy-3-fluorophenyl]-1-(4-fluorophenyl)-2-oxopyridine-3-carboxamide;N-[4-[1-ethyl-6-(1H-pyrazol-4-yl)indazol-5-yl]oxy-3-fluorophenyl]-1-(4-fluorophenyl)-2-oxo-6-propan-2-yloxypyridine-3-carboxamide;N-[4-[1-ethyl-6-(1H-pyrazol-4-yl)indazol-5-yl]oxy-3-fluorophenyl]-1-(4-fluorophenyl)-2-oxo-6-(2,2,2-trifluoroethoxy)pyridine-3-carboxamide has a molecular weight of 1869.79 g/mol, XLogP of 20.03, 27 rotatable bonds, 6 hydrogen bond donors, and 24 hydrogen bond acceptors.
Where does this data come from?
All data for 6-cyclopropyloxy-N-[4-[1-ethyl-6-(1H-pyrazol-4-yl)indazol-5-yl]oxy-3-fluorophenyl]-1-(4-fluorophenyl)-2-oxopyridine-3-carboxamide;N-[4-[1-ethyl-6-(1H-pyrazol-4-yl)indazol-5-yl]oxy-3-fluorophenyl]-1-(4-fluorophenyl)-2-oxo-6-propan-2-yloxypyridine-3-carboxamide;N-[4-[1-ethyl-6-(1H-pyrazol-4-yl)indazol-5-yl]oxy-3-fluorophenyl]-1-(4-fluorophenyl)-2-oxo-6-(2,2,2-trifluoroethoxy)pyridine-3-carboxamide is sourced from PubChem (CID 167641682), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).