9-cyclopropyl-N-(4-methyl-5-piperazin-1-yl-2-pyridinyl)pyrrolo[3,2-h]quinazolin-2-amine;9-cyclopropyl-N-(5-piperazin-1-yl-2-pyridinyl)pyrrolo[3,2-h]quinazolin-2-amine;N-[5-[(2R,6S)-2,6-dimethylmorpholin-4-yl]-2-pyridinyl]-9-ethylpyrrolo[3,2-h]quinazolin-2-amine;9-ethyl-N-[5-(2-methylmorpholin-4-yl)-2-pyridinyl]pyrrolo[3,2-h]quinazolin-2-amine;9-ethyl-N-(5-morpholin-4-yl-2-pyridinyl)pyrrolo[3,2-h]quinazolin-2-amine;dihydrochloride

C111H122Cl2N32O3 — CID 167655080

About 9-cyclopropyl-N-(4-methyl-5-piperazin-1-yl-2-pyridinyl)pyrrolo[3,2-h]quinazolin-2-amine;9-cyclopropyl-N-(5-piperazin-1-yl-2-pyridinyl)pyrrolo[3,2-h]quinazolin-2-amine;N-[5-[(2R,6S)-2,6-dimethylmorpholin-4-yl]-2-pyridinyl]-9-ethylpyrrolo[3,2-h]quinazolin-2-amine;9-ethyl-N-[5-(2-methylmorpholin-4-yl)-2-pyridinyl]pyrrolo[3,2-h]quinazolin-2-amine;9-ethyl-N-(5-morpholin-4-yl-2-pyridinyl)pyrrolo[3,2-h]quinazolin-2-amine;dihydrochloride

9-cyclopropyl-N-(4-methyl-5-piperazin-1-yl-2-pyridinyl)pyrrolo[3,2-h]quinazolin-2-amine;9-cyclopropyl-N-(5-piperazin-1-yl-2-pyridinyl)pyrrolo[3,2-h]quinazolin-2-amine;N-[5-[(2R,6S)-2,6-dimethylmorpholin-4-yl]-2-pyridinyl]-9-ethylpyrrolo[3,2-h]quinazolin-2-amine;9-ethyl-N-[5-(2-methylmorpholin-4-yl)-2-pyridinyl]pyrrolo[3,2-h]quinazolin-2-amine;9-ethyl-N-(5-morpholin-4-yl-2-pyridinyl)pyrrolo[3,2-h]quinazolin-2-amine;dihydrochloride (PubChem CID 167655080) has the molecular formula C111H122Cl2N32O3 and a molecular weight of 2023.32 g/mol. Its IUPAC name is 9-cyclopropyl-N-(4-methyl-5-piperazin-1-yl-2-pyridinyl)pyrrolo[3,2-h]quinazolin-2-amine;9-cyclopropyl-N-(5-piperazin-1-yl-2-pyridinyl)pyrrolo[3,2-h]quinazolin-2-amine;N-[5-[(2R,6S)-2,6-dimethylmorpholin-4-yl]-2-pyridinyl]-9-ethylpyrrolo[3,2-h]quinazolin-2-amine;9-ethyl-N-[5-(2-methylmorpholin-4-yl)-2-pyridinyl]pyrrolo[3,2-h]quinazolin-2-amine;9-ethyl-N-(5-morpholin-4-yl-2-pyridinyl)pyrrolo[3,2-h]quinazolin-2-amine;dihydrochloride.

Molecular Properties

• Compound Name: 9-cyclopropyl-N-(4-methyl-5-piperazin-1-yl-2-pyridinyl)pyrrolo[3,2-h]quinazolin-2-amine;9-cyclopropyl-N-(5-piperazin-1-yl-2-pyridinyl)pyrrolo[3,2-h]quinazolin-2-amine;N-[5-[(2R,6S)-2,6-dimethylmorpholin-4-yl]-2-pyridinyl]-9-ethylpyrrolo[3,2-h]quinazolin-2-amine;9-ethyl-N-[5-(2-methylmorpholin-4-yl)-2-pyridinyl]pyrrolo[3,2-h]quinazolin-2-amine;9-ethyl-N-(5-morpholin-4-yl-2-pyridinyl)pyrrolo[3,2-h]quinazolin-2-amine;dihydrochloride
• PubChem CID: 167655080
• Molecular Formula: C111H122Cl2N32O3
• Molecular Weight: 2023.32 g/mol
• Exact Mass: 2020.98
• IUPAC Name: 9-cyclopropyl-N-(4-methyl-5-piperazin-1-yl-2-pyridinyl)pyrrolo[3,2-h]quinazolin-2-amine;9-cyclopropyl-N-(5-piperazin-1-yl-2-pyridinyl)pyrrolo[3,2-h]quinazolin-2-amine;N-[5-[(2R,6S)-2,6-dimethylmorpholin-4-yl]-2-pyridinyl]-9-ethylpyrrolo[3,2-h]quinazolin-2-amine;9-ethyl-N-[5-(2-methylmorpholin-4-yl)-2-pyridinyl]pyrrolo[3,2-h]quinazolin-2-amine;9-ethyl-N-(5-morpholin-4-yl-2-pyridinyl)pyrrolo[3,2-h]quinazolin-2-amine;dihydrochloride
• SMILES: CCn1ccc2ccc3cnc(Nc4ccc(N5CCOC(C)C5)cn4)nc3c21.CCn1ccc2ccc3cnc(Nc4ccc(N5CCOCC5)cn4)nc3c21.CCn1ccc2ccc3cnc(Nc4ccc(N5C[C@@H](C)O[C@@H](C)C5)cn4)nc3c21.Cc1cc(Nc2ncc3ccc4ccn(C5CC5)c4c3n2)ncc1N1CCNCC1.Cl.Cl.c1cc(Nc2ncc3ccc4ccn(C5CC5)c4c3n2)ncc1N1CCNCC1
• InChI: InChI=1S/C23H25N7.C23H26N6O.C22H23N7.C22H24N6O.C21H22N6O.2ClH/c1-15-12-20(25-14-19(15)29-10-7-24-8-11-29)27-23-26-13-17-3-2-16-6-9-30(18-4-5-18)22(16)21(17)28-23;1-4-28-10-9-17-5-6-18-11-25-23(27-21(18)22(17)28)26-20-8-7-19(12-24-20)29-13-15(2)30-16(3)14-29;1-2-16-13-25-22(27-20(16)21-15(1)7-10-29(21)17-3-4-17)26-19-6-5-18(14-24-19)28-11-8-23-9-12-28;1-3-27-9-8-16-4-5-17-12-24-22(26-20(17)21(16)27)25-19-7-6-18(13-23-19)28-10-11-29-15(2)14-28;1-2-26-8-7-15-3-4-16-13-23-21(25-19(16)20(15)26)24-18-6-5-17(14-22-18)27-9-11-28-12-10-27;;/h2-3,6,9,12-14,18,24H,4-5,7-8,10-11H2,1H3,(H,25,26,27,28);5-12,15-16H,4,13-14H2,1-3H3,(H,24,25,26,27);1-2,5-7,10,13-14,17,23H,3-4,8-9,11-12H2,(H,24,25,26,27);4-9,12-13,15H,3,10-11,14H2,1-2H3,(H,23,24,25,26);3-8,13-14H,2,9-12H2,1H3,(H,22,23,24,25);2*1H/t;15-,16+
• InChIKey: NEUBNNUFYCPHFP-GWSJPVAQSA-N
• XLogP: 19.99
• TPSA: 346.10 Ų
• H-Bond Donors: 7
• H-Bond Acceptors: 35
• Rotatable Bonds: 20
• Heavy Atoms: 148
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2023.32
LogP ≤ 5	19.99
H-Bond Donors ≤ 5	7
H-Bond Acceptors ≤ 10	35

Frequently Asked Questions

What is the IUPAC name of 9-cyclopropyl-N-(4-methyl-5-piperazin-1-yl-2-pyridinyl)pyrrolo[3,2-h]quinazolin-2-amine;9-cyclopropyl-N-(5-piperazin-1-yl-2-pyridinyl)pyrrolo[3,2-h]quinazolin-2-amine;N-[5-[(2R,6S)-2,6-dimethylmorpholin-4-yl]-2-pyridinyl]-9-ethylpyrrolo[3,2-h]quinazolin-2-amine;9-ethyl-N-[5-(2-methylmorpholin-4-yl)-2-pyridinyl]pyrrolo[3,2-h]quinazolin-2-amine;9-ethyl-N-(5-morpholin-4-yl-2-pyridinyl)pyrrolo[3,2-h]quinazolin-2-amine;dihydrochloride?

The IUPAC name of 9-cyclopropyl-N-(4-methyl-5-piperazin-1-yl-2-pyridinyl)pyrrolo[3,2-h]quinazolin-2-amine;9-cyclopropyl-N-(5-piperazin-1-yl-2-pyridinyl)pyrrolo[3,2-h]quinazolin-2-amine;N-[5-[(2R,6S)-2,6-dimethylmorpholin-4-yl]-2-pyridinyl]-9-ethylpyrrolo[3,2-h]quinazolin-2-amine;9-ethyl-N-[5-(2-methylmorpholin-4-yl)-2-pyridinyl]pyrrolo[3,2-h]quinazolin-2-amine;9-ethyl-N-(5-morpholin-4-yl-2-pyridinyl)pyrrolo[3,2-h]quinazolin-2-amine;dihydrochloride (CID 167655080) is 9-cyclopropyl-N-(4-methyl-5-piperazin-1-yl-2-pyridinyl)pyrrolo[3,2-h]quinazolin-2-amine;9-cyclopropyl-N-(5-piperazin-1-yl-2-pyridinyl)pyrrolo[3,2-h]quinazolin-2-amine;N-[5-[(2R,6S)-2,6-dimethylmorpholin-4-yl]-2-pyridinyl]-9-ethylpyrrolo[3,2-h]quinazolin-2-amine;9-ethyl-N-[5-(2-methylmorpholin-4-yl)-2-pyridinyl]pyrrolo[3,2-h]quinazolin-2-amine;9-ethyl-N-(5-morpholin-4-yl-2-pyridinyl)pyrrolo[3,2-h]quinazolin-2-amine;dihydrochloride.

What is the SMILES notation for 9-cyclopropyl-N-(4-methyl-5-piperazin-1-yl-2-pyridinyl)pyrrolo[3,2-h]quinazolin-2-amine;9-cyclopropyl-N-(5-piperazin-1-yl-2-pyridinyl)pyrrolo[3,2-h]quinazolin-2-amine;N-[5-[(2R,6S)-2,6-dimethylmorpholin-4-yl]-2-pyridinyl]-9-ethylpyrrolo[3,2-h]quinazolin-2-amine;9-ethyl-N-[5-(2-methylmorpholin-4-yl)-2-pyridinyl]pyrrolo[3,2-h]quinazolin-2-amine;9-ethyl-N-(5-morpholin-4-yl-2-pyridinyl)pyrrolo[3,2-h]quinazolin-2-amine;dihydrochloride?

The canonical SMILES for 9-cyclopropyl-N-(4-methyl-5-piperazin-1-yl-2-pyridinyl)pyrrolo[3,2-h]quinazolin-2-amine;9-cyclopropyl-N-(5-piperazin-1-yl-2-pyridinyl)pyrrolo[3,2-h]quinazolin-2-amine;N-[5-[(2R,6S)-2,6-dimethylmorpholin-4-yl]-2-pyridinyl]-9-ethylpyrrolo[3,2-h]quinazolin-2-amine;9-ethyl-N-[5-(2-methylmorpholin-4-yl)-2-pyridinyl]pyrrolo[3,2-h]quinazolin-2-amine;9-ethyl-N-(5-morpholin-4-yl-2-pyridinyl)pyrrolo[3,2-h]quinazolin-2-amine;dihydrochloride is CCn1ccc2ccc3cnc(Nc4ccc(N5CCOC(C)C5)cn4)nc3c21.CCn1ccc2ccc3cnc(Nc4ccc(N5CCOCC5)cn4)nc3c21.CCn1ccc2ccc3cnc(Nc4ccc(N5C[C@@H](C)O[C@@H](C)C5)cn4)nc3c21.Cc1cc(Nc2ncc3ccc4ccn(C5CC5)c4c3n2)ncc1N1CCNCC1.Cl.Cl.c1cc(Nc2ncc3ccc4ccn(C5CC5)c4c3n2)ncc1N1CCNCC1.

What is the InChIKey of 9-cyclopropyl-N-(4-methyl-5-piperazin-1-yl-2-pyridinyl)pyrrolo[3,2-h]quinazolin-2-amine;9-cyclopropyl-N-(5-piperazin-1-yl-2-pyridinyl)pyrrolo[3,2-h]quinazolin-2-amine;N-[5-[(2R,6S)-2,6-dimethylmorpholin-4-yl]-2-pyridinyl]-9-ethylpyrrolo[3,2-h]quinazolin-2-amine;9-ethyl-N-[5-(2-methylmorpholin-4-yl)-2-pyridinyl]pyrrolo[3,2-h]quinazolin-2-amine;9-ethyl-N-(5-morpholin-4-yl-2-pyridinyl)pyrrolo[3,2-h]quinazolin-2-amine;dihydrochloride?

The InChIKey is NEUBNNUFYCPHFP-GWSJPVAQSA-N. The full InChI is InChI=1S/C23H25N7.C23H26N6O.C22H23N7.C22H24N6O.C21H22N6O.2ClH/c1-15-12-20(25-14-19(15)29-10-7-24-8-11-29)27-23-26-13-17-3-2-16-6-9-30(18-4-5-18)22(16)21(17)28-23;1-4-28-10-9-17-5-6-18-11-25-23(27-21(18)22(17)28)26-20-8-7-19(12-24-20)29-13-15(2)30-16(3)14-29;1-2-16-13-25-22(27-20(16)21-15(1)7-10-29(21)17-3-4-17)26-19-6-5-18(14-24-19)28-11-8-23-9-12-28;1-3-27-9-8-16-4-5-17-12-24-22(26-20(17)21(16)27)25-19-7-6-18(13-23-19)28-10-11-29-15(2)14-28;1-2-26-8-7-15-3-4-16-13-23-21(25-19(16)20(15)26)24-18-6-5-17(14-22-18)27-9-11-28-12-10-27;;/h2-3,6,9,12-14,18,24H,4-5,7-8,10-11H2,1H3,(H,25,26,27,28);5-12,15-16H,4,13-14H2,1-3H3,(H,24,25,26,27);1-2,5-7,10,13-14,17,23H,3-4,8-9,11-12H2,(H,24,25,26,27);4-9,12-13,15H,3,10-11,14H2,1-2H3,(H,23,24,25,26);3-8,13-14H,2,9-12H2,1H3,(H,22,23,24,25);2*1H/t;15-,16+;;;;;.

What are the key properties of 9-cyclopropyl-N-(4-methyl-5-piperazin-1-yl-2-pyridinyl)pyrrolo[3,2-h]quinazolin-2-amine;9-cyclopropyl-N-(5-piperazin-1-yl-2-pyridinyl)pyrrolo[3,2-h]quinazolin-2-amine;N-[5-[(2R,6S)-2,6-dimethylmorpholin-4-yl]-2-pyridinyl]-9-ethylpyrrolo[3,2-h]quinazolin-2-amine;9-ethyl-N-[5-(2-methylmorpholin-4-yl)-2-pyridinyl]pyrrolo[3,2-h]quinazolin-2-amine;9-ethyl-N-(5-morpholin-4-yl-2-pyridinyl)pyrrolo[3,2-h]quinazolin-2-amine;dihydrochloride?

9-cyclopropyl-N-(4-methyl-5-piperazin-1-yl-2-pyridinyl)pyrrolo[3,2-h]quinazolin-2-amine;9-cyclopropyl-N-(5-piperazin-1-yl-2-pyridinyl)pyrrolo[3,2-h]quinazolin-2-amine;N-[5-[(2R,6S)-2,6-dimethylmorpholin-4-yl]-2-pyridinyl]-9-ethylpyrrolo[3,2-h]quinazolin-2-amine;9-ethyl-N-[5-(2-methylmorpholin-4-yl)-2-pyridinyl]pyrrolo[3,2-h]quinazolin-2-amine;9-ethyl-N-(5-morpholin-4-yl-2-pyridinyl)pyrrolo[3,2-h]quinazolin-2-amine;dihydrochloride has a molecular weight of 2023.32 g/mol, XLogP of 19.99, 20 rotatable bonds, 7 hydrogen bond donors, and 35 hydrogen bond acceptors.

Where does this data come from?

All data for 9-cyclopropyl-N-(4-methyl-5-piperazin-1-yl-2-pyridinyl)pyrrolo[3,2-h]quinazolin-2-amine;9-cyclopropyl-N-(5-piperazin-1-yl-2-pyridinyl)pyrrolo[3,2-h]quinazolin-2-amine;N-[5-[(2R,6S)-2,6-dimethylmorpholin-4-yl]-2-pyridinyl]-9-ethylpyrrolo[3,2-h]quinazolin-2-amine;9-ethyl-N-[5-(2-methylmorpholin-4-yl)-2-pyridinyl]pyrrolo[3,2-h]quinazolin-2-amine;9-ethyl-N-(5-morpholin-4-yl-2-pyridinyl)pyrrolo[3,2-h]quinazolin-2-amine;dihydrochloride is sourced from PubChem (CID 167655080), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).