(1S)-1-[3-amino-6-fluoro-5-[[[3-[4-fluoro-3-(trifluoromethyl)phenoxy]cyclobutyl]amino]methyl]isoquinolin-8-yl]ethane-1,2-diol;2-[3-amino-6-fluoro-8-(hydroxymethyl)isoquinolin-5-yl]-N-[3-[4-fluoro-3-(trifluoromethyl)phenoxy]cyclobutyl]acetamide;2-(3-amino-6-fluoroisoquinolin-5-yl)-N-[3-[4-fluoro-3-(trifluoromethyl)phenoxy]cyclobutyl]acetamide;3-[(2,6-difluoro-3-pyridinyl)oxy]-N-[(6-fluoroisoquinolin-5-yl)methyl]cyclobutan-1-amine;ethyl 4-[3-[(6-fluoroisoquinolin-5-yl)methylamino]cyclobutyl]oxybenzoate;(1R)-1-[6-fluoro-5-[[[3-[4-fluoro-3-(trifluoromethyl)phenoxy]cyclobutyl]amino]methyl]isoquinolin-8-yl]ethane-1,2-diol;bis(N-[(6-fluoroisoquinolin-5-yl)methyl]-3-[4-fluoro-3-(trifluoromethyl)phenoxy]-1-methylcyclobutan-1-amine);N-[(6-fluoroisoquinolin-5-yl)methyl]-3-[3-(trifluoromethyl)phenoxy]cyclobutan-1-amine;5-[[[3-[4-fluoro-3-(trifluoromethyl)phenoxy]cyclobutyl]amino]methyl]isoquinolin-8-amine;[5-[[[3-[4-fluoro-3-(trifluoromethyl)phenoxy]cyclobutyl]amino]methyl]isoquinolin-8-yl]methanol;3-[4-fluoro-3-(trifluoromethyl)phenoxy]-N-[(6-methylisoquinolin-5-yl)methyl]cyclobutan-1-amine;3-[4-fluoro-3-(trifluoromethyl)phenoxy]-N-(quinazolin-8-ylmethyl)cyclobutan-1-amine;methane

C289H276F54N32O23 — CID 167682234

IUPAC(1S)-1-[3-amino-6-fluoro-5-[[[3-[4-fluoro-3-(trifluoromethyl)phenoxy]cyclobutyl]amino]methyl]isoquinolin-8-yl]ethane-1,2-diol;2-[3-amino-6-fluoro-8-(hydroxymethyl)isoquinolin-5-yl]-N-[3-[4-fluoro-3-(trifluoromethyl)phenoxy]cyclobutyl]acetamide;2-(3-amino-6-fluoroisoquinolin-5-yl)-N-[3-[4-fluoro-3-(trifluoromethyl)phenoxy]cyclobutyl]acetamide;3-[(2,6-difluoro-3-pyridinyl)oxy]-N-[(6-fluoroisoquinolin-5-yl)methyl]cyclobutan-1-amine;ethyl 4-[3-[(6-fluoroisoquinolin-5-yl)methylamino]cyclobutyl]oxybenzoate;(1R)-1-[6-fluoro-5-[[[3-[4-fluoro-3-(trifluoromethyl)phenoxy]cyclobutyl]amino]methyl]isoquinolin-8-yl]ethane-1,2-diol;bis(N-[(6-fluoroisoquinolin-5-yl)methyl]-3-[4-fluoro-3-(trifluoromethyl)phenoxy]-1-methylcyclobutan-1-amine);N-[(6-fluoroisoquinolin-5-yl)methyl]-3-[3-(trifluoromethyl)phenoxy]cyclobutan-1-amine;5-[[[3-[4-fluoro-3-(trifluoromethyl)phenoxy]cyclobutyl]amino]methyl]isoquinolin-8-amine;[5-[[[3-[4-fluoro-3-(trifluoromethyl)phenoxy]cyclobutyl]amino]methyl]isoquinolin-8-yl]methanol;3-[4-fluoro-3-(trifluoromethyl)phenoxy]-N-[(6-methylisoquinolin-5-yl)methyl]cyclobutan-1-amine;3-[4-fluoro-3-(trifluoromethyl)phenoxy]-N-(quinazolin-8-ylmethyl)cyclobutan-1-amine;methane
SMILESC.C.C.C.C.C.CC1(NCc2c(F)ccc3cnccc23)CC(Oc2ccc(F)c(C(F)(F)F)c2)C1.CC1(NCc2c(F)ccc3cnccc23)CC(Oc2ccc(F)c(C(F)(F)F)c2)C1.CCOC(=O)c1ccc(OC2CC(NCc3c(F)ccc4cnccc34)C2)cc1.Cc1ccc2cnccc2c1CNC1CC(Oc2ccc(F)c(C(F)(F)F)c2)C1.Fc1ccc(OC2CC(NCc3c(F)ccc4cnccc34)C2)c(F)n1.Fc1ccc(OC2CC(NCc3cccc4cncnc34)C2)cc1C(F)(F)F.Fc1ccc2cnccc2c1CNC1CC(Oc2cccc(C(F)(F)F)c2)C1.Nc1cc2c(CC(=O)NC3CC(Oc4ccc(F)c(C(F)(F)F)c4)C3)c(F)cc(CO)c2cn1.Nc1cc2c(CC(=O)NC3CC(Oc4ccc(F)c(C(F)(F)F)c4)C3)c(F)ccc2cn1.Nc1cc2c(CNC3CC(Oc4ccc(F)c(C(F)(F)F)c4)C3)c(F)cc([C@H](O)CO)c2cn1.Nc1ccc(CNC2CC(Oc3ccc(F)c(C(F)(F)F)c3)C2)c2ccncc12.OC[C@H](O)c1cc(F)c(CNC2CC(Oc3ccc(F)c(C(F)(F)F)c3)C2)c2ccncc12.OCc1ccc(CNC2CC(Oc3ccc(F)c(C(F)(F)F)c3)C2)c2ccncc12
InChIInChI=1S/C23H20F5N3O3.C23H22F5N3O3.C23H21F5N2O3.C23H23FN2O3.C22H18F5N3O2.2C22H19F5N2O.C22H20F4N2O2.C22H20F4N2O.C21H19F4N3O.C21H18F4N2O.C20H17F4N3O.C19H16F3N3O.6CH4/c24-19-2-1-13(6-18(19)23(26,27)28)34-14-4-12(5-14)31-22(33)8-16-15-7-21(29)30-9-17(15)11(10-32)3-20(16)25;24-19-2-1-12(5-18(19)23(26,27)28)34-13-3-11(4-13)30-9-17-14-7-22(29)31-8-16(14)15(6-20(17)25)21(33)10-32;24-20-2-1-13(7-19(20)23(26,27)28)33-14-5-12(6-14)30-10-18-15-3-4-29-9-17(15)16(8-21(18)25)22(32)11-31;1-2-28-23(27)15-3-6-18(7-4-15)29-19-11-17(12-19)26-14-21-20-9-10-25-13-16(20)5-8-22(21)24;23-18-3-1-11-10-29-20(28)8-15(11)16(18)9-21(31)30-12-5-14(6-12)32-13-2-4-19(24)17(7-13)22(25,26)27;2*1-21(29-12-17-16-6-7-28-11-13(16)2-4-19(17)23)9-15(10-21)30-14-3-5-20(24)18(8-14)22(25,26)27;23-21-4-3-16(9-20(21)22(24,25)26)30-17-7-15(8-17)28-10-13-1-2-14(12-29)19-11-27-6-5-18(13)19;1-13-2-3-14-11-27-7-6-18(14)19(13)12-28-15-8-17(9-15)29-16-4-5-21(23)20(10-16)22(24,25)26;22-19-3-2-14(9-18(19)21(23,24)25)29-15-7-13(8-15)28-10-12-1-4-20(26)17-11-27-6-5-16(12)17;22-20-5-4-13-11-26-7-6-18(13)19(20)12-27-15-9-17(10-15)28-16-3-1-2-14(8-16)21(23,24)25;21-18-5-4-15(8-17(18)20(22,23)24)28-16-6-14(7-16)26-10-13-3-1-2-12-9-25-11-27-19(12)13;20-16-2-1-11-9-23-6-5-14(11)15(16)10-24-12-7-13(8-12)26-17-3-4-18(21)25-19(17)22;;;;;;/h1-3,6-7,9,12,14,32H,4-5,8,10H2,(H2,29,30)(H,31,33);1-2,5-8,11,13,21,30,32-33H,3-4,9-10H2,(H2,29,31);1-4,7-9,12,14,22,30-32H,5-6,10-11H2;3-10,13,17,19,26H,2,11-12,14H2,1H3;1-4,7-8,10,12,14H,5-6,9H2,(H2,28,29)(H,30,31);2*2-8,11,15,29H,9-10,12H2,1H3;1-6,9,11,15,17,28-29H,7-8,10,12H2;2-7,10-11,15,17,28H,8-9,12H2,1H3;1-6,9,11,13,15,28H,7-8,10,26H2;1-8,11,15,17,27H,9-10,12H2;1-5,8-9,11,14,16,26H,6-7,10H2;1-6,9,12-13,24H,7-8,10H2;6*1H4/t;11?,13?,21-;12?,14?,22-;;;;;;;;;;;;;;;;/m.10................/s1
InChIKeyVSACJUUQBUVAHY-JKKDLLTESA-N
MW5591.48 g/mol
LogP63.65
Rot. Bonds73

About (1S)-1-[3-amino-6-fluoro-5-[[[3-[4-fluoro-3-(trifluoromethyl)phenoxy]cyclobutyl]amino]methyl]isoquinolin-8-yl]ethane-1,2-diol;2-[3-amino-6-fluoro-8-(hydroxymethyl)isoquinolin-5-yl]-N-[3-[4-fluoro-3-(trifluoromethyl)phenoxy]cyclobutyl]acetamide;2-(3-amino-6-fluoroisoquinolin-5-yl)-N-[3-[4-fluoro-3-(trifluoromethyl)phenoxy]cyclobutyl]acetamide;3-[(2,6-difluoro-3-pyridinyl)oxy]-N-[(6-fluoroisoquinolin-5-yl)methyl]cyclobutan-1-amine;ethyl 4-[3-[(6-fluoroisoquinolin-5-yl)methylamino]cyclobutyl]oxybenzoate;(1R)-1-[6-fluoro-5-[[[3-[4-fluoro-3-(trifluoromethyl)phenoxy]cyclobutyl]amino]methyl]isoquinolin-8-yl]ethane-1,2-diol;bis(N-[(6-fluoroisoquinolin-5-yl)methyl]-3-[4-fluoro-3-(trifluoromethyl)phenoxy]-1-methylcyclobutan-1-amine);N-[(6-fluoroisoquinolin-5-yl)methyl]-3-[3-(trifluoromethyl)phenoxy]cyclobutan-1-amine;5-[[[3-[4-fluoro-3-(trifluoromethyl)phenoxy]cyclobutyl]amino]methyl]isoquinolin-8-amine;[5-[[[3-[4-fluoro-3-(trifluoromethyl)phenoxy]cyclobutyl]amino]methyl]isoquinolin-8-yl]methanol;3-[4-fluoro-3-(trifluoromethyl)phenoxy]-N-[(6-methylisoquinolin-5-yl)methyl]cyclobutan-1-amine;3-[4-fluoro-3-(trifluoromethyl)phenoxy]-N-(quinazolin-8-ylmethyl)cyclobutan-1-amine;methane

(1S)-1-[3-amino-6-fluoro-5-[[[3-[4-fluoro-3-(trifluoromethyl)phenoxy]cyclobutyl]amino]methyl]isoquinolin-8-yl]ethane-1,2-diol;2-[3-amino-6-fluoro-8-(hydroxymethyl)isoquinolin-5-yl]-N-[3-[4-fluoro-3-(trifluoromethyl)phenoxy]cyclobutyl]acetamide;2-(3-amino-6-fluoroisoquinolin-5-yl)-N-[3-[4-fluoro-3-(trifluoromethyl)phenoxy]cyclobutyl]acetamide;3-[(2,6-difluoro-3-pyridinyl)oxy]-N-[(6-fluoroisoquinolin-5-yl)methyl]cyclobutan-1-amine;ethyl 4-[3-[(6-fluoroisoquinolin-5-yl)methylamino]cyclobutyl]oxybenzoate;(1R)-1-[6-fluoro-5-[[[3-[4-fluoro-3-(trifluoromethyl)phenoxy]cyclobutyl]amino]methyl]isoquinolin-8-yl]ethane-1,2-diol;bis(N-[(6-fluoroisoquinolin-5-yl)methyl]-3-[4-fluoro-3-(trifluoromethyl)phenoxy]-1-methylcyclobutan-1-amine);N-[(6-fluoroisoquinolin-5-yl)methyl]-3-[3-(trifluoromethyl)phenoxy]cyclobutan-1-amine;5-[[[3-[4-fluoro-3-(trifluoromethyl)phenoxy]cyclobutyl]amino]methyl]isoquinolin-8-amine;[5-[[[3-[4-fluoro-3-(trifluoromethyl)phenoxy]cyclobutyl]amino]methyl]isoquinolin-8-yl]methanol;3-[4-fluoro-3-(trifluoromethyl)phenoxy]-N-[(6-methylisoquinolin-5-yl)methyl]cyclobutan-1-amine;3-[4-fluoro-3-(trifluoromethyl)phenoxy]-N-(quinazolin-8-ylmethyl)cyclobutan-1-amine;methane (PubChem CID 167682234) has the molecular formula C289H276F54N32O23 and a molecular weight of 5591.48 g/mol. Its IUPAC name is (1S)-1-[3-amino-6-fluoro-5-[[[3-[4-fluoro-3-(trifluoromethyl)phenoxy]cyclobutyl]amino]methyl]isoquinolin-8-yl]ethane-1,2-diol;2-[3-amino-6-fluoro-8-(hydroxymethyl)isoquinolin-5-yl]-N-[3-[4-fluoro-3-(trifluoromethyl)phenoxy]cyclobutyl]acetamide;2-(3-amino-6-fluoroisoquinolin-5-yl)-N-[3-[4-fluoro-3-(trifluoromethyl)phenoxy]cyclobutyl]acetamide;3-[(2,6-difluoro-3-pyridinyl)oxy]-N-[(6-fluoroisoquinolin-5-yl)methyl]cyclobutan-1-amine;ethyl 4-[3-[(6-fluoroisoquinolin-5-yl)methylamino]cyclobutyl]oxybenzoate;(1R)-1-[6-fluoro-5-[[[3-[4-fluoro-3-(trifluoromethyl)phenoxy]cyclobutyl]amino]methyl]isoquinolin-8-yl]ethane-1,2-diol;bis(N-[(6-fluoroisoquinolin-5-yl)methyl]-3-[4-fluoro-3-(trifluoromethyl)phenoxy]-1-methylcyclobutan-1-amine);N-[(6-fluoroisoquinolin-5-yl)methyl]-3-[3-(trifluoromethyl)phenoxy]cyclobutan-1-amine;5-[[[3-[4-fluoro-3-(trifluoromethyl)phenoxy]cyclobutyl]amino]methyl]isoquinolin-8-amine;[5-[[[3-[4-fluoro-3-(trifluoromethyl)phenoxy]cyclobutyl]amino]methyl]isoquinolin-8-yl]methanol;3-[4-fluoro-3-(trifluoromethyl)phenoxy]-N-[(6-methylisoquinolin-5-yl)methyl]cyclobutan-1-amine;3-[4-fluoro-3-(trifluoromethyl)phenoxy]-N-(quinazolin-8-ylmethyl)cyclobutan-1-amine;methane.

Molecular Properties

Compound Name(1S)-1-[3-amino-6-fluoro-5-[[[3-[4-fluoro-3-(trifluoromethyl)phenoxy]cyclobutyl]amino]methyl]isoquinolin-8-yl]ethane-1,2-diol;2-[3-amino-6-fluoro-8-(hydroxymethyl)isoquinolin-5-yl]-N-[3-[4-fluoro-3-(trifluoromethyl)phenoxy]cyclobutyl]acetamide;2-(3-amino-6-fluoroisoquinolin-5-yl)-N-[3-[4-fluoro-3-(trifluoromethyl)phenoxy]cyclobutyl]acetamide;3-[(2,6-difluoro-3-pyridinyl)oxy]-N-[(6-fluoroisoquinolin-5-yl)methyl]cyclobutan-1-amine;ethyl 4-[3-[(6-fluoroisoquinolin-5-yl)methylamino]cyclobutyl]oxybenzoate;(1R)-1-[6-fluoro-5-[[[3-[4-fluoro-3-(trifluoromethyl)phenoxy]cyclobutyl]amino]methyl]isoquinolin-8-yl]ethane-1,2-diol;bis(N-[(6-fluoroisoquinolin-5-yl)methyl]-3-[4-fluoro-3-(trifluoromethyl)phenoxy]-1-methylcyclobutan-1-amine);N-[(6-fluoroisoquinolin-5-yl)methyl]-3-[3-(trifluoromethyl)phenoxy]cyclobutan-1-amine;5-[[[3-[4-fluoro-3-(trifluoromethyl)phenoxy]cyclobutyl]amino]methyl]isoquinolin-8-amine;[5-[[[3-[4-fluoro-3-(trifluoromethyl)phenoxy]cyclobutyl]amino]methyl]isoquinolin-8-yl]methanol;3-[4-fluoro-3-(trifluoromethyl)phenoxy]-N-[(6-methylisoquinolin-5-yl)methyl]cyclobutan-1-amine;3-[4-fluoro-3-(trifluoromethyl)phenoxy]-N-(quinazolin-8-ylmethyl)cyclobutan-1-amine;methane
PubChem CID167682234
Molecular FormulaC289H276F54N32O23
Molecular Weight5591.48 g/mol
Exact Mass5588.05
IUPAC Name(1S)-1-[3-amino-6-fluoro-5-[[[3-[4-fluoro-3-(trifluoromethyl)phenoxy]cyclobutyl]amino]methyl]isoquinolin-8-yl]ethane-1,2-diol;2-[3-amino-6-fluoro-8-(hydroxymethyl)isoquinolin-5-yl]-N-[3-[4-fluoro-3-(trifluoromethyl)phenoxy]cyclobutyl]acetamide;2-(3-amino-6-fluoroisoquinolin-5-yl)-N-[3-[4-fluoro-3-(trifluoromethyl)phenoxy]cyclobutyl]acetamide;3-[(2,6-difluoro-3-pyridinyl)oxy]-N-[(6-fluoroisoquinolin-5-yl)methyl]cyclobutan-1-amine;ethyl 4-[3-[(6-fluoroisoquinolin-5-yl)methylamino]cyclobutyl]oxybenzoate;(1R)-1-[6-fluoro-5-[[[3-[4-fluoro-3-(trifluoromethyl)phenoxy]cyclobutyl]amino]methyl]isoquinolin-8-yl]ethane-1,2-diol;bis(N-[(6-fluoroisoquinolin-5-yl)methyl]-3-[4-fluoro-3-(trifluoromethyl)phenoxy]-1-methylcyclobutan-1-amine);N-[(6-fluoroisoquinolin-5-yl)methyl]-3-[3-(trifluoromethyl)phenoxy]cyclobutan-1-amine;5-[[[3-[4-fluoro-3-(trifluoromethyl)phenoxy]cyclobutyl]amino]methyl]isoquinolin-8-amine;[5-[[[3-[4-fluoro-3-(trifluoromethyl)phenoxy]cyclobutyl]amino]methyl]isoquinolin-8-yl]methanol;3-[4-fluoro-3-(trifluoromethyl)phenoxy]-N-[(6-methylisoquinolin-5-yl)methyl]cyclobutan-1-amine;3-[4-fluoro-3-(trifluoromethyl)phenoxy]-N-(quinazolin-8-ylmethyl)cyclobutan-1-amine;methane
SMILESC.C.C.C.C.C.CC1(NCc2c(F)ccc3cnccc23)CC(Oc2ccc(F)c(C(F)(F)F)c2)C1.CC1(NCc2c(F)ccc3cnccc23)CC(Oc2ccc(F)c(C(F)(F)F)c2)C1.CCOC(=O)c1ccc(OC2CC(NCc3c(F)ccc4cnccc34)C2)cc1.Cc1ccc2cnccc2c1CNC1CC(Oc2ccc(F)c(C(F)(F)F)c2)C1.Fc1ccc(OC2CC(NCc3c(F)ccc4cnccc34)C2)c(F)n1.Fc1ccc(OC2CC(NCc3cccc4cncnc34)C2)cc1C(F)(F)F.Fc1ccc2cnccc2c1CNC1CC(Oc2cccc(C(F)(F)F)c2)C1.Nc1cc2c(CC(=O)NC3CC(Oc4ccc(F)c(C(F)(F)F)c4)C3)c(F)cc(CO)c2cn1.Nc1cc2c(CC(=O)NC3CC(Oc4ccc(F)c(C(F)(F)F)c4)C3)c(F)ccc2cn1.Nc1cc2c(CNC3CC(Oc4ccc(F)c(C(F)(F)F)c4)C3)c(F)cc([C@H](O)CO)c2cn1.Nc1ccc(CNC2CC(Oc3ccc(F)c(C(F)(F)F)c3)C2)c2ccncc12.OC[C@H](O)c1cc(F)c(CNC2CC(Oc3ccc(F)c(C(F)(F)F)c3)C2)c2ccncc12.OCc1ccc(CNC2CC(Oc3ccc(F)c(C(F)(F)F)c3)C2)c2ccncc12
InChIInChI=1S/C23H20F5N3O3.C23H22F5N3O3.C23H21F5N2O3.C23H23FN2O3.C22H18F5N3O2.2C22H19F5N2O.C22H20F4N2O2.C22H20F4N2O.C21H19F4N3O.C21H18F4N2O.C20H17F4N3O.C19H16F3N3O.6CH4/c24-19-2-1-13(6-18(19)23(26,27)28)34-14-4-12(5-14)31-22(33)8-16-15-7-21(29)30-9-17(15)11(10-32)3-20(16)25;24-19-2-1-12(5-18(19)23(26,27)28)34-13-3-11(4-13)30-9-17-14-7-22(29)31-8-16(14)15(6-20(17)25)21(33)10-32;24-20-2-1-13(7-19(20)23(26,27)28)33-14-5-12(6-14)30-10-18-15-3-4-29-9-17(15)16(8-21(18)25)22(32)11-31;1-2-28-23(27)15-3-6-18(7-4-15)29-19-11-17(12-19)26-14-21-20-9-10-25-13-16(20)5-8-22(21)24;23-18-3-1-11-10-29-20(28)8-15(11)16(18)9-21(31)30-12-5-14(6-12)32-13-2-4-19(24)17(7-13)22(25,26)27;2*1-21(29-12-17-16-6-7-28-11-13(16)2-4-19(17)23)9-15(10-21)30-14-3-5-20(24)18(8-14)22(25,26)27;23-21-4-3-16(9-20(21)22(24,25)26)30-17-7-15(8-17)28-10-13-1-2-14(12-29)19-11-27-6-5-18(13)19;1-13-2-3-14-11-27-7-6-18(14)19(13)12-28-15-8-17(9-15)29-16-4-5-21(23)20(10-16)22(24,25)26;22-19-3-2-14(9-18(19)21(23,24)25)29-15-7-13(8-15)28-10-12-1-4-20(26)17-11-27-6-5-16(12)17;22-20-5-4-13-11-26-7-6-18(13)19(20)12-27-15-9-17(10-15)28-16-3-1-2-14(8-16)21(23,24)25;21-18-5-4-15(8-17(18)20(22,23)24)28-16-6-14(7-16)26-10-13-3-1-2-12-9-25-11-27-19(12)13;20-16-2-1-11-9-23-6-5-14(11)15(16)10-24-12-7-13(8-12)26-17-3-4-18(21)25-19(17)22;;;;;;/h1-3,6-7,9,12,14,32H,4-5,8,10H2,(H2,29,30)(H,31,33);1-2,5-8,11,13,21,30,32-33H,3-4,9-10H2,(H2,29,31);1-4,7-9,12,14,22,30-32H,5-6,10-11H2;3-10,13,17,19,26H,2,11-12,14H2,1H3;1-4,7-8,10,12,14H,5-6,9H2,(H2,28,29)(H,30,31);2*2-8,11,15,29H,9-10,12H2,1H3;1-6,9,11,15,17,28-29H,7-8,10,12H2;2-7,10-11,15,17,28H,8-9,12H2,1H3;1-6,9,11,13,15,28H,7-8,10,26H2;1-8,11,15,17,27H,9-10,12H2;1-5,8-9,11,14,16,26H,6-7,10H2;1-6,9,12-13,24H,7-8,10H2;6*1H4/t;11?,13?,21-;12?,14?,22-;;;;;;;;;;;;;;;;/m.10................/s1
InChIKeyVSACJUUQBUVAHY-JKKDLLTESA-N
XLogP63.65
TPSA755.63 Ų
H-Bond Donors23
H-Bond Acceptors53
Rotatable Bonds73
Heavy Atoms398
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5005591.48
LogP ≤ 563.65
H-Bond Donors ≤ 523
H-Bond Acceptors ≤ 1053

Analyze (1S)-1-[3-amino-6-fluoro-5-[[[3-[4-fluoro-3-(trifluoromethyl)phenoxy]cyclobutyl]amino]methyl]isoquinolin-8-yl]ethane-1,2-diol;2-[3-amino-6-fluoro-8-(hydroxymethyl)isoquinolin-5-yl]-N-[3-[4-fluoro-3-(trifluoromethyl)phenoxy]cyclobutyl]acetamide;2-(3-amino-6-fluoroisoquinolin-5-yl)-N-[3-[4-fluoro-3-(trifluoromethyl)phenoxy]cyclobutyl]acetamide;3-[(2,6-difluoro-3-pyridinyl)oxy]-N-[(6-fluoroisoquinolin-5-yl)methyl]cyclobutan-1-amine;ethyl 4-[3-[(6-fluoroisoquinolin-5-yl)methylamino]cyclobutyl]oxybenzoate;(1R)-1-[6-fluoro-5-[[[3-[4-fluoro-3-(trifluoromethyl)phenoxy]cyclobutyl]amino]methyl]isoquinolin-8-yl]ethane-1,2-diol;bis(N-[(6-fluoroisoquinolin-5-yl)methyl]-3-[4-fluoro-3-(trifluoromethyl)phenoxy]-1-methylcyclobutan-1-amine);N-[(6-fluoroisoquinolin-5-yl)methyl]-3-[3-(trifluoromethyl)phenoxy]cyclobutan-1-amine;5-[[[3-[4-fluoro-3-(trifluoromethyl)phenoxy]cyclobutyl]amino]methyl]isoquinolin-8-amine;[5-[[[3-[4-fluoro-3-(trifluoromethyl)phenoxy]cyclobutyl]amino]methyl]isoquinolin-8-yl]methanol;3-[4-fluoro-3-(trifluoromethyl)phenoxy]-N-[(6-methylisoquinolin-5-yl)methyl]cyclobutan-1-amine;3-[4-fluoro-3-(trifluoromethyl)phenoxy]-N-(quinazolin-8-ylmethyl)cyclobutan-1-amine;methane with MolForge

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What is the IUPAC name of (1S)-1-[3-amino-6-fluoro-5-[[[3-[4-fluoro-3-(trifluoromethyl)phenoxy]cyclobutyl]amino]methyl]isoquinolin-8-yl]ethane-1,2-diol;2-[3-amino-6-fluoro-8-(hydroxymethyl)isoquinolin-5-yl]-N-[3-[4-fluoro-3-(trifluoromethyl)phenoxy]cyclobutyl]acetamide;2-(3-amino-6-fluoroisoquinolin-5-yl)-N-[3-[4-fluoro-3-(trifluoromethyl)phenoxy]cyclobutyl]acetamide;3-[(2,6-difluoro-3-pyridinyl)oxy]-N-[(6-fluoroisoquinolin-5-yl)methyl]cyclobutan-1-amine;ethyl 4-[3-[(6-fluoroisoquinolin-5-yl)methylamino]cyclobutyl]oxybenzoate;(1R)-1-[6-fluoro-5-[[[3-[4-fluoro-3-(trifluoromethyl)phenoxy]cyclobutyl]amino]methyl]isoquinolin-8-yl]ethane-1,2-diol;bis(N-[(6-fluoroisoquinolin-5-yl)methyl]-3-[4-fluoro-3-(trifluoromethyl)phenoxy]-1-methylcyclobutan-1-amine);N-[(6-fluoroisoquinolin-5-yl)methyl]-3-[3-(trifluoromethyl)phenoxy]cyclobutan-1-amine;5-[[[3-[4-fluoro-3-(trifluoromethyl)phenoxy]cyclobutyl]amino]methyl]isoquinolin-8-amine;[5-[[[3-[4-fluoro-3-(trifluoromethyl)phenoxy]cyclobutyl]amino]methyl]isoquinolin-8-yl]methanol;3-[4-fluoro-3-(trifluoromethyl)phenoxy]-N-[(6-methylisoquinolin-5-yl)methyl]cyclobutan-1-amine;3-[4-fluoro-3-(trifluoromethyl)phenoxy]-N-(quinazolin-8-ylmethyl)cyclobutan-1-amine;methane?
The IUPAC name of (1S)-1-[3-amino-6-fluoro-5-[[[3-[4-fluoro-3-(trifluoromethyl)phenoxy]cyclobutyl]amino]methyl]isoquinolin-8-yl]ethane-1,2-diol;2-[3-amino-6-fluoro-8-(hydroxymethyl)isoquinolin-5-yl]-N-[3-[4-fluoro-3-(trifluoromethyl)phenoxy]cyclobutyl]acetamide;2-(3-amino-6-fluoroisoquinolin-5-yl)-N-[3-[4-fluoro-3-(trifluoromethyl)phenoxy]cyclobutyl]acetamide;3-[(2,6-difluoro-3-pyridinyl)oxy]-N-[(6-fluoroisoquinolin-5-yl)methyl]cyclobutan-1-amine;ethyl 4-[3-[(6-fluoroisoquinolin-5-yl)methylamino]cyclobutyl]oxybenzoate;(1R)-1-[6-fluoro-5-[[[3-[4-fluoro-3-(trifluoromethyl)phenoxy]cyclobutyl]amino]methyl]isoquinolin-8-yl]ethane-1,2-diol;bis(N-[(6-fluoroisoquinolin-5-yl)methyl]-3-[4-fluoro-3-(trifluoromethyl)phenoxy]-1-methylcyclobutan-1-amine);N-[(6-fluoroisoquinolin-5-yl)methyl]-3-[3-(trifluoromethyl)phenoxy]cyclobutan-1-amine;5-[[[3-[4-fluoro-3-(trifluoromethyl)phenoxy]cyclobutyl]amino]methyl]isoquinolin-8-amine;[5-[[[3-[4-fluoro-3-(trifluoromethyl)phenoxy]cyclobutyl]amino]methyl]isoquinolin-8-yl]methanol;3-[4-fluoro-3-(trifluoromethyl)phenoxy]-N-[(6-methylisoquinolin-5-yl)methyl]cyclobutan-1-amine;3-[4-fluoro-3-(trifluoromethyl)phenoxy]-N-(quinazolin-8-ylmethyl)cyclobutan-1-amine;methane (CID 167682234) is (1S)-1-[3-amino-6-fluoro-5-[[[3-[4-fluoro-3-(trifluoromethyl)phenoxy]cyclobutyl]amino]methyl]isoquinolin-8-yl]ethane-1,2-diol;2-[3-amino-6-fluoro-8-(hydroxymethyl)isoquinolin-5-yl]-N-[3-[4-fluoro-3-(trifluoromethyl)phenoxy]cyclobutyl]acetamide;2-(3-amino-6-fluoroisoquinolin-5-yl)-N-[3-[4-fluoro-3-(trifluoromethyl)phenoxy]cyclobutyl]acetamide;3-[(2,6-difluoro-3-pyridinyl)oxy]-N-[(6-fluoroisoquinolin-5-yl)methyl]cyclobutan-1-amine;ethyl 4-[3-[(6-fluoroisoquinolin-5-yl)methylamino]cyclobutyl]oxybenzoate;(1R)-1-[6-fluoro-5-[[[3-[4-fluoro-3-(trifluoromethyl)phenoxy]cyclobutyl]amino]methyl]isoquinolin-8-yl]ethane-1,2-diol;bis(N-[(6-fluoroisoquinolin-5-yl)methyl]-3-[4-fluoro-3-(trifluoromethyl)phenoxy]-1-methylcyclobutan-1-amine);N-[(6-fluoroisoquinolin-5-yl)methyl]-3-[3-(trifluoromethyl)phenoxy]cyclobutan-1-amine;5-[[[3-[4-fluoro-3-(trifluoromethyl)phenoxy]cyclobutyl]amino]methyl]isoquinolin-8-amine;[5-[[[3-[4-fluoro-3-(trifluoromethyl)phenoxy]cyclobutyl]amino]methyl]isoquinolin-8-yl]methanol;3-[4-fluoro-3-(trifluoromethyl)phenoxy]-N-[(6-methylisoquinolin-5-yl)methyl]cyclobutan-1-amine;3-[4-fluoro-3-(trifluoromethyl)phenoxy]-N-(quinazolin-8-ylmethyl)cyclobutan-1-amine;methane.
What is the SMILES notation for (1S)-1-[3-amino-6-fluoro-5-[[[3-[4-fluoro-3-(trifluoromethyl)phenoxy]cyclobutyl]amino]methyl]isoquinolin-8-yl]ethane-1,2-diol;2-[3-amino-6-fluoro-8-(hydroxymethyl)isoquinolin-5-yl]-N-[3-[4-fluoro-3-(trifluoromethyl)phenoxy]cyclobutyl]acetamide;2-(3-amino-6-fluoroisoquinolin-5-yl)-N-[3-[4-fluoro-3-(trifluoromethyl)phenoxy]cyclobutyl]acetamide;3-[(2,6-difluoro-3-pyridinyl)oxy]-N-[(6-fluoroisoquinolin-5-yl)methyl]cyclobutan-1-amine;ethyl 4-[3-[(6-fluoroisoquinolin-5-yl)methylamino]cyclobutyl]oxybenzoate;(1R)-1-[6-fluoro-5-[[[3-[4-fluoro-3-(trifluoromethyl)phenoxy]cyclobutyl]amino]methyl]isoquinolin-8-yl]ethane-1,2-diol;bis(N-[(6-fluoroisoquinolin-5-yl)methyl]-3-[4-fluoro-3-(trifluoromethyl)phenoxy]-1-methylcyclobutan-1-amine);N-[(6-fluoroisoquinolin-5-yl)methyl]-3-[3-(trifluoromethyl)phenoxy]cyclobutan-1-amine;5-[[[3-[4-fluoro-3-(trifluoromethyl)phenoxy]cyclobutyl]amino]methyl]isoquinolin-8-amine;[5-[[[3-[4-fluoro-3-(trifluoromethyl)phenoxy]cyclobutyl]amino]methyl]isoquinolin-8-yl]methanol;3-[4-fluoro-3-(trifluoromethyl)phenoxy]-N-[(6-methylisoquinolin-5-yl)methyl]cyclobutan-1-amine;3-[4-fluoro-3-(trifluoromethyl)phenoxy]-N-(quinazolin-8-ylmethyl)cyclobutan-1-amine;methane?
The canonical SMILES for (1S)-1-[3-amino-6-fluoro-5-[[[3-[4-fluoro-3-(trifluoromethyl)phenoxy]cyclobutyl]amino]methyl]isoquinolin-8-yl]ethane-1,2-diol;2-[3-amino-6-fluoro-8-(hydroxymethyl)isoquinolin-5-yl]-N-[3-[4-fluoro-3-(trifluoromethyl)phenoxy]cyclobutyl]acetamide;2-(3-amino-6-fluoroisoquinolin-5-yl)-N-[3-[4-fluoro-3-(trifluoromethyl)phenoxy]cyclobutyl]acetamide;3-[(2,6-difluoro-3-pyridinyl)oxy]-N-[(6-fluoroisoquinolin-5-yl)methyl]cyclobutan-1-amine;ethyl 4-[3-[(6-fluoroisoquinolin-5-yl)methylamino]cyclobutyl]oxybenzoate;(1R)-1-[6-fluoro-5-[[[3-[4-fluoro-3-(trifluoromethyl)phenoxy]cyclobutyl]amino]methyl]isoquinolin-8-yl]ethane-1,2-diol;bis(N-[(6-fluoroisoquinolin-5-yl)methyl]-3-[4-fluoro-3-(trifluoromethyl)phenoxy]-1-methylcyclobutan-1-amine);N-[(6-fluoroisoquinolin-5-yl)methyl]-3-[3-(trifluoromethyl)phenoxy]cyclobutan-1-amine;5-[[[3-[4-fluoro-3-(trifluoromethyl)phenoxy]cyclobutyl]amino]methyl]isoquinolin-8-amine;[5-[[[3-[4-fluoro-3-(trifluoromethyl)phenoxy]cyclobutyl]amino]methyl]isoquinolin-8-yl]methanol;3-[4-fluoro-3-(trifluoromethyl)phenoxy]-N-[(6-methylisoquinolin-5-yl)methyl]cyclobutan-1-amine;3-[4-fluoro-3-(trifluoromethyl)phenoxy]-N-(quinazolin-8-ylmethyl)cyclobutan-1-amine;methane is C.C.C.C.C.C.CC1(NCc2c(F)ccc3cnccc23)CC(Oc2ccc(F)c(C(F)(F)F)c2)C1.CC1(NCc2c(F)ccc3cnccc23)CC(Oc2ccc(F)c(C(F)(F)F)c2)C1.CCOC(=O)c1ccc(OC2CC(NCc3c(F)ccc4cnccc34)C2)cc1.Cc1ccc2cnccc2c1CNC1CC(Oc2ccc(F)c(C(F)(F)F)c2)C1.Fc1ccc(OC2CC(NCc3c(F)ccc4cnccc34)C2)c(F)n1.Fc1ccc(OC2CC(NCc3cccc4cncnc34)C2)cc1C(F)(F)F.Fc1ccc2cnccc2c1CNC1CC(Oc2cccc(C(F)(F)F)c2)C1.Nc1cc2c(CC(=O)NC3CC(Oc4ccc(F)c(C(F)(F)F)c4)C3)c(F)cc(CO)c2cn1.Nc1cc2c(CC(=O)NC3CC(Oc4ccc(F)c(C(F)(F)F)c4)C3)c(F)ccc2cn1.Nc1cc2c(CNC3CC(Oc4ccc(F)c(C(F)(F)F)c4)C3)c(F)cc([C@H](O)CO)c2cn1.Nc1ccc(CNC2CC(Oc3ccc(F)c(C(F)(F)F)c3)C2)c2ccncc12.OC[C@H](O)c1cc(F)c(CNC2CC(Oc3ccc(F)c(C(F)(F)F)c3)C2)c2ccncc12.OCc1ccc(CNC2CC(Oc3ccc(F)c(C(F)(F)F)c3)C2)c2ccncc12.
What is the InChIKey of (1S)-1-[3-amino-6-fluoro-5-[[[3-[4-fluoro-3-(trifluoromethyl)phenoxy]cyclobutyl]amino]methyl]isoquinolin-8-yl]ethane-1,2-diol;2-[3-amino-6-fluoro-8-(hydroxymethyl)isoquinolin-5-yl]-N-[3-[4-fluoro-3-(trifluoromethyl)phenoxy]cyclobutyl]acetamide;2-(3-amino-6-fluoroisoquinolin-5-yl)-N-[3-[4-fluoro-3-(trifluoromethyl)phenoxy]cyclobutyl]acetamide;3-[(2,6-difluoro-3-pyridinyl)oxy]-N-[(6-fluoroisoquinolin-5-yl)methyl]cyclobutan-1-amine;ethyl 4-[3-[(6-fluoroisoquinolin-5-yl)methylamino]cyclobutyl]oxybenzoate;(1R)-1-[6-fluoro-5-[[[3-[4-fluoro-3-(trifluoromethyl)phenoxy]cyclobutyl]amino]methyl]isoquinolin-8-yl]ethane-1,2-diol;bis(N-[(6-fluoroisoquinolin-5-yl)methyl]-3-[4-fluoro-3-(trifluoromethyl)phenoxy]-1-methylcyclobutan-1-amine);N-[(6-fluoroisoquinolin-5-yl)methyl]-3-[3-(trifluoromethyl)phenoxy]cyclobutan-1-amine;5-[[[3-[4-fluoro-3-(trifluoromethyl)phenoxy]cyclobutyl]amino]methyl]isoquinolin-8-amine;[5-[[[3-[4-fluoro-3-(trifluoromethyl)phenoxy]cyclobutyl]amino]methyl]isoquinolin-8-yl]methanol;3-[4-fluoro-3-(trifluoromethyl)phenoxy]-N-[(6-methylisoquinolin-5-yl)methyl]cyclobutan-1-amine;3-[4-fluoro-3-(trifluoromethyl)phenoxy]-N-(quinazolin-8-ylmethyl)cyclobutan-1-amine;methane?
The InChIKey is VSACJUUQBUVAHY-JKKDLLTESA-N. The full InChI is InChI=1S/C23H20F5N3O3.C23H22F5N3O3.C23H21F5N2O3.C23H23FN2O3.C22H18F5N3O2.2C22H19F5N2O.C22H20F4N2O2.C22H20F4N2O.C21H19F4N3O.C21H18F4N2O.C20H17F4N3O.C19H16F3N3O.6CH4/c24-19-2-1-13(6-18(19)23(26,27)28)34-14-4-12(5-14)31-22(33)8-16-15-7-21(29)30-9-17(15)11(10-32)3-20(16)25;24-19-2-1-12(5-18(19)23(26,27)28)34-13-3-11(4-13)30-9-17-14-7-22(29)31-8-16(14)15(6-20(17)25)21(33)10-32;24-20-2-1-13(7-19(20)23(26,27)28)33-14-5-12(6-14)30-10-18-15-3-4-29-9-17(15)16(8-21(18)25)22(32)11-31;1-2-28-23(27)15-3-6-18(7-4-15)29-19-11-17(12-19)26-14-21-20-9-10-25-13-16(20)5-8-22(21)24;23-18-3-1-11-10-29-20(28)8-15(11)16(18)9-21(31)30-12-5-14(6-12)32-13-2-4-19(24)17(7-13)22(25,26)27;2*1-21(29-12-17-16-6-7-28-11-13(16)2-4-19(17)23)9-15(10-21)30-14-3-5-20(24)18(8-14)22(25,26)27;23-21-4-3-16(9-20(21)22(24,25)26)30-17-7-15(8-17)28-10-13-1-2-14(12-29)19-11-27-6-5-18(13)19;1-13-2-3-14-11-27-7-6-18(14)19(13)12-28-15-8-17(9-15)29-16-4-5-21(23)20(10-16)22(24,25)26;22-19-3-2-14(9-18(19)21(23,24)25)29-15-7-13(8-15)28-10-12-1-4-20(26)17-11-27-6-5-16(12)17;22-20-5-4-13-11-26-7-6-18(13)19(20)12-27-15-9-17(10-15)28-16-3-1-2-14(8-16)21(23,24)25;21-18-5-4-15(8-17(18)20(22,23)24)28-16-6-14(7-16)26-10-13-3-1-2-12-9-25-11-27-19(12)13;20-16-2-1-11-9-23-6-5-14(11)15(16)10-24-12-7-13(8-12)26-17-3-4-18(21)25-19(17)22;;;;;;/h1-3,6-7,9,12,14,32H,4-5,8,10H2,(H2,29,30)(H,31,33);1-2,5-8,11,13,21,30,32-33H,3-4,9-10H2,(H2,29,31);1-4,7-9,12,14,22,30-32H,5-6,10-11H2;3-10,13,17,19,26H,2,11-12,14H2,1H3;1-4,7-8,10,12,14H,5-6,9H2,(H2,28,29)(H,30,31);2*2-8,11,15,29H,9-10,12H2,1H3;1-6,9,11,15,17,28-29H,7-8,10,12H2;2-7,10-11,15,17,28H,8-9,12H2,1H3;1-6,9,11,13,15,28H,7-8,10,26H2;1-8,11,15,17,27H,9-10,12H2;1-5,8-9,11,14,16,26H,6-7,10H2;1-6,9,12-13,24H,7-8,10H2;6*1H4/t;11?,13?,21-;12?,14?,22-;;;;;;;;;;;;;;;;/m.10................/s1.
What are the key properties of (1S)-1-[3-amino-6-fluoro-5-[[[3-[4-fluoro-3-(trifluoromethyl)phenoxy]cyclobutyl]amino]methyl]isoquinolin-8-yl]ethane-1,2-diol;2-[3-amino-6-fluoro-8-(hydroxymethyl)isoquinolin-5-yl]-N-[3-[4-fluoro-3-(trifluoromethyl)phenoxy]cyclobutyl]acetamide;2-(3-amino-6-fluoroisoquinolin-5-yl)-N-[3-[4-fluoro-3-(trifluoromethyl)phenoxy]cyclobutyl]acetamide;3-[(2,6-difluoro-3-pyridinyl)oxy]-N-[(6-fluoroisoquinolin-5-yl)methyl]cyclobutan-1-amine;ethyl 4-[3-[(6-fluoroisoquinolin-5-yl)methylamino]cyclobutyl]oxybenzoate;(1R)-1-[6-fluoro-5-[[[3-[4-fluoro-3-(trifluoromethyl)phenoxy]cyclobutyl]amino]methyl]isoquinolin-8-yl]ethane-1,2-diol;bis(N-[(6-fluoroisoquinolin-5-yl)methyl]-3-[4-fluoro-3-(trifluoromethyl)phenoxy]-1-methylcyclobutan-1-amine);N-[(6-fluoroisoquinolin-5-yl)methyl]-3-[3-(trifluoromethyl)phenoxy]cyclobutan-1-amine;5-[[[3-[4-fluoro-3-(trifluoromethyl)phenoxy]cyclobutyl]amino]methyl]isoquinolin-8-amine;[5-[[[3-[4-fluoro-3-(trifluoromethyl)phenoxy]cyclobutyl]amino]methyl]isoquinolin-8-yl]methanol;3-[4-fluoro-3-(trifluoromethyl)phenoxy]-N-[(6-methylisoquinolin-5-yl)methyl]cyclobutan-1-amine;3-[4-fluoro-3-(trifluoromethyl)phenoxy]-N-(quinazolin-8-ylmethyl)cyclobutan-1-amine;methane?
(1S)-1-[3-amino-6-fluoro-5-[[[3-[4-fluoro-3-(trifluoromethyl)phenoxy]cyclobutyl]amino]methyl]isoquinolin-8-yl]ethane-1,2-diol;2-[3-amino-6-fluoro-8-(hydroxymethyl)isoquinolin-5-yl]-N-[3-[4-fluoro-3-(trifluoromethyl)phenoxy]cyclobutyl]acetamide;2-(3-amino-6-fluoroisoquinolin-5-yl)-N-[3-[4-fluoro-3-(trifluoromethyl)phenoxy]cyclobutyl]acetamide;3-[(2,6-difluoro-3-pyridinyl)oxy]-N-[(6-fluoroisoquinolin-5-yl)methyl]cyclobutan-1-amine;ethyl 4-[3-[(6-fluoroisoquinolin-5-yl)methylamino]cyclobutyl]oxybenzoate;(1R)-1-[6-fluoro-5-[[[3-[4-fluoro-3-(trifluoromethyl)phenoxy]cyclobutyl]amino]methyl]isoquinolin-8-yl]ethane-1,2-diol;bis(N-[(6-fluoroisoquinolin-5-yl)methyl]-3-[4-fluoro-3-(trifluoromethyl)phenoxy]-1-methylcyclobutan-1-amine);N-[(6-fluoroisoquinolin-5-yl)methyl]-3-[3-(trifluoromethyl)phenoxy]cyclobutan-1-amine;5-[[[3-[4-fluoro-3-(trifluoromethyl)phenoxy]cyclobutyl]amino]methyl]isoquinolin-8-amine;[5-[[[3-[4-fluoro-3-(trifluoromethyl)phenoxy]cyclobutyl]amino]methyl]isoquinolin-8-yl]methanol;3-[4-fluoro-3-(trifluoromethyl)phenoxy]-N-[(6-methylisoquinolin-5-yl)methyl]cyclobutan-1-amine;3-[4-fluoro-3-(trifluoromethyl)phenoxy]-N-(quinazolin-8-ylmethyl)cyclobutan-1-amine;methane has a molecular weight of 5591.48 g/mol, XLogP of 63.65, 73 rotatable bonds, 23 hydrogen bond donors, and 53 hydrogen bond acceptors.
Where does this data come from?
All data for (1S)-1-[3-amino-6-fluoro-5-[[[3-[4-fluoro-3-(trifluoromethyl)phenoxy]cyclobutyl]amino]methyl]isoquinolin-8-yl]ethane-1,2-diol;2-[3-amino-6-fluoro-8-(hydroxymethyl)isoquinolin-5-yl]-N-[3-[4-fluoro-3-(trifluoromethyl)phenoxy]cyclobutyl]acetamide;2-(3-amino-6-fluoroisoquinolin-5-yl)-N-[3-[4-fluoro-3-(trifluoromethyl)phenoxy]cyclobutyl]acetamide;3-[(2,6-difluoro-3-pyridinyl)oxy]-N-[(6-fluoroisoquinolin-5-yl)methyl]cyclobutan-1-amine;ethyl 4-[3-[(6-fluoroisoquinolin-5-yl)methylamino]cyclobutyl]oxybenzoate;(1R)-1-[6-fluoro-5-[[[3-[4-fluoro-3-(trifluoromethyl)phenoxy]cyclobutyl]amino]methyl]isoquinolin-8-yl]ethane-1,2-diol;bis(N-[(6-fluoroisoquinolin-5-yl)methyl]-3-[4-fluoro-3-(trifluoromethyl)phenoxy]-1-methylcyclobutan-1-amine);N-[(6-fluoroisoquinolin-5-yl)methyl]-3-[3-(trifluoromethyl)phenoxy]cyclobutan-1-amine;5-[[[3-[4-fluoro-3-(trifluoromethyl)phenoxy]cyclobutyl]amino]methyl]isoquinolin-8-amine;[5-[[[3-[4-fluoro-3-(trifluoromethyl)phenoxy]cyclobutyl]amino]methyl]isoquinolin-8-yl]methanol;3-[4-fluoro-3-(trifluoromethyl)phenoxy]-N-[(6-methylisoquinolin-5-yl)methyl]cyclobutan-1-amine;3-[4-fluoro-3-(trifluoromethyl)phenoxy]-N-(quinazolin-8-ylmethyl)cyclobutan-1-amine;methane is sourced from PubChem (CID 167682234), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).