N-[(3R,4S)-4-[[8-[(3-aminophenyl)methylamino]-6-(2,6-dichloro-3,5-dimethoxyphenyl)pyrido[3,4-d]pyrimidin-2-yl]amino]oxolan-3-yl]prop-2-enamide;1-[(3R,4S)-4-[[8-anilino-6-(2,6-dichloro-3,5-dimethoxyphenyl)pyrido[3,4-d]pyrimidin-2-yl]amino]oxolan-3-yl]but-3-en-2-one;1-[(3R,4S)-4-[[8-(benzylamino)-6-(2,6-dichloro-3,5-dimethoxyphenyl)pyrido[3,4-d]pyrimidin-2-yl]amino]oxolan-3-yl]but-3-en-2-one;N-[(3R,4S)-4-[[8-(cyclopentylmethylamino)-6-(2,6-dichloro-3,5-dimethoxyphenyl)pyrido[3,4-d]pyrimidin-2-yl]amino]oxolan-3-yl]prop-2-enamide;N-[(3R,4S)-4-[[6-(2,6-dichloro-3,5-dimethoxyphenyl)-8-[(3,3-difluorocyclopentyl)amino]pyrido[3,4-d]pyrimidin-2-yl]amino]oxolan-3-yl]prop-2-enamide;N-[(3R,4S)-4-[[6-(2,6-dichloro-3,5-dimethoxyphenyl)-8-[[1-(2-hydroxyethyl)pyrazol-4-yl]methylamino]pyrido[3,4-d]pyrimidin-2-yl]amino]oxolan-3-yl]prop-2-enamide;N-[(3R,4S)-4-[[6-(2,6-dichloro-3,5-dimethoxyphenyl)-8-[(1-methylpyrazol-4-yl)methylamino]pyrido[3,4-d]pyrimidin-2-yl]amino]oxolan-3-yl]prop-2-enamide;N-[(3R,4S)-4-[[6-(2,6-dichloro-3,5-dimethoxyphenyl)-8-(2-phenylethylamino)pyrido[3,4-d]pyrimidin-2-yl]amino]oxolan-3-yl]prop-2-enamide

C228H233Cl16F2N51O33 — CID 167696715

IUPACN-[(3R,4S)-4-[[8-[(3-aminophenyl)methylamino]-6-(2,6-dichloro-3,5-dimethoxyphenyl)pyrido[3,4-d]pyrimidin-2-yl]amino]oxolan-3-yl]prop-2-enamide;1-[(3R,4S)-4-[[8-anilino-6-(2,6-dichloro-3,5-dimethoxyphenyl)pyrido[3,4-d]pyrimidin-2-yl]amino]oxolan-3-yl]but-3-en-2-one;1-[(3R,4S)-4-[[8-(benzylamino)-6-(2,6-dichloro-3,5-dimethoxyphenyl)pyrido[3,4-d]pyrimidin-2-yl]amino]oxolan-3-yl]but-3-en-2-one;N-[(3R,4S)-4-[[8-(cyclopentylmethylamino)-6-(2,6-dichloro-3,5-dimethoxyphenyl)pyrido[3,4-d]pyrimidin-2-yl]amino]oxolan-3-yl]prop-2-enamide;N-[(3R,4S)-4-[[6-(2,6-dichloro-3,5-dimethoxyphenyl)-8-[(3,3-difluorocyclopentyl)amino]pyrido[3,4-d]pyrimidin-2-yl]amino]oxolan-3-yl]prop-2-enamide;N-[(3R,4S)-4-[[6-(2,6-dichloro-3,5-dimethoxyphenyl)-8-[[1-(2-hydroxyethyl)pyrazol-4-yl]methylamino]pyrido[3,4-d]pyrimidin-2-yl]amino]oxolan-3-yl]prop-2-enamide;N-[(3R,4S)-4-[[6-(2,6-dichloro-3,5-dimethoxyphenyl)-8-[(1-methylpyrazol-4-yl)methylamino]pyrido[3,4-d]pyrimidin-2-yl]amino]oxolan-3-yl]prop-2-enamide;N-[(3R,4S)-4-[[6-(2,6-dichloro-3,5-dimethoxyphenyl)-8-(2-phenylethylamino)pyrido[3,4-d]pyrimidin-2-yl]amino]oxolan-3-yl]prop-2-enamide
SMILESC=CC(=O)C[C@H]1COC[C@H]1Nc1ncc2cc(-c3c(Cl)c(OC)cc(OC)c3Cl)nc(NCc3ccccc3)c2n1.C=CC(=O)C[C@H]1COC[C@H]1Nc1ncc2cc(-c3c(Cl)c(OC)cc(OC)c3Cl)nc(Nc3ccccc3)c2n1.C=CC(=O)N[C@H]1COC[C@H]1Nc1ncc2cc(-c3c(Cl)c(OC)cc(OC)c3Cl)nc(NC3CCC(F)(F)C3)c2n1.C=CC(=O)N[C@H]1COC[C@H]1Nc1ncc2cc(-c3c(Cl)c(OC)cc(OC)c3Cl)nc(NCC3CCCC3)c2n1.C=CC(=O)N[C@H]1COC[C@H]1Nc1ncc2cc(-c3c(Cl)c(OC)cc(OC)c3Cl)nc(NCCc3ccccc3)c2n1.C=CC(=O)N[C@H]1COC[C@H]1Nc1ncc2cc(-c3c(Cl)c(OC)cc(OC)c3Cl)nc(NCc3cccc(N)c3)c2n1.C=CC(=O)N[C@H]1COC[C@H]1Nc1ncc2cc(-c3c(Cl)c(OC)cc(OC)c3Cl)nc(NCc3cnn(C)c3)c2n1.C=CC(=O)N[C@H]1COC[C@H]1Nc1ncc2cc(-c3c(Cl)c(OC)cc(OC)c3Cl)nc(NCc3cnn(CCO)c3)c2n1
InChIInChI=1S/C30H30Cl2N6O4.C30H29Cl2N5O4.C29H29Cl2N7O4.C29H27Cl2N5O4.C28H30Cl2N8O5.C28H32Cl2N6O4.C27H28Cl2F2N6O4.C27H28Cl2N8O4/c1-4-24(39)35-20-15-42-16-21(20)37-30-34-14-18-12-19(25-26(31)22(40-2)13-23(41-3)27(25)32)36-29(28(18)38-30)33-11-10-17-8-6-5-7-9-17;1-4-20(38)10-19-15-41-16-22(19)36-30-34-14-18-11-21(25-26(31)23(39-2)12-24(40-3)27(25)32)35-29(28(18)37-30)33-13-17-8-6-5-7-9-17;1-4-23(39)35-19-13-42-14-20(19)37-29-34-12-16-9-18(24-25(30)21(40-2)10-22(41-3)26(24)31)36-28(27(16)38-29)33-11-15-6-5-7-17(32)8-15;1-4-19(37)10-17-14-40-15-21(17)35-29-32-13-16-11-20(24-25(30)22(38-2)12-23(39-3)26(24)31)34-28(27(16)36-29)33-18-8-6-5-7-9-18;1-4-22(40)34-18-13-43-14-19(18)36-28-32-11-16-7-17(23-24(29)20(41-2)8-21(42-3)25(23)30)35-27(26(16)37-28)31-9-15-10-33-38(12-15)5-6-39;1-4-22(37)33-18-13-40-14-19(18)35-28-32-12-16-9-17(23-24(29)20(38-2)10-21(39-3)25(23)30)34-27(26(16)36-28)31-11-15-7-5-6-8-15;1-4-20(38)34-16-11-41-12-17(16)36-26-32-10-13-7-15(21-22(28)18(39-2)8-19(40-3)23(21)29)35-25(24(13)37-26)33-14-5-6-27(30,31)9-14;1-5-21(38)33-17-12-41-13-18(17)35-27-31-10-15-6-16(22-23(28)19(39-3)7-20(40-4)24(22)29)34-26(25(15)36-27)30-8-14-9-32-37(2)11-14/h4-9,12-14,20-21H,1,10-11,15-16H2,2-3H3,(H,33,36)(H,35,39)(H,34,37,38);4-9,11-12,14,19,22H,1,10,13,15-16H2,2-3H3,(H,33,35)(H,34,36,37);4-10,12,19-20H,1,11,13-14,32H2,2-3H3,(H,33,36)(H,35,39)(H,34,37,38);4-9,11-13,17,21H,1,10,14-15H2,2-3H3,(H,33,34)(H,32,35,36);4,7-8,10-12,18-19,39H,1,5-6,9,13-14H2,2-3H3,(H,31,35)(H,34,40)(H,32,36,37);4,9-10,12,15,18-19H,1,5-8,11,13-14H2,2-3H3,(H,31,34)(H,33,37)(H,32,35,36);4,7-8,10,14,16-17H,1,5-6,9,11-12H2,2-3H3,(H,33,35)(H,34,38)(H,32,36,37);5-7,9-11,17-18H,1,8,12-13H2,2-4H3,(H,30,34)(H,33,38)(H,31,35,36)/t20-,21+;19-,22+;19-,20+;17-,21+;2*18-,19+;14?,16-,17+;17-,18+/m00000000/s1
InChIKeyXTOFNSJXVVHNBJ-ZSSRQADQSA-N
MW4820.94 g/mol
LogP39.71
Rot. Bonds83

About N-[(3R,4S)-4-[[8-[(3-aminophenyl)methylamino]-6-(2,6-dichloro-3,5-dimethoxyphenyl)pyrido[3,4-d]pyrimidin-2-yl]amino]oxolan-3-yl]prop-2-enamide;1-[(3R,4S)-4-[[8-anilino-6-(2,6-dichloro-3,5-dimethoxyphenyl)pyrido[3,4-d]pyrimidin-2-yl]amino]oxolan-3-yl]but-3-en-2-one;1-[(3R,4S)-4-[[8-(benzylamino)-6-(2,6-dichloro-3,5-dimethoxyphenyl)pyrido[3,4-d]pyrimidin-2-yl]amino]oxolan-3-yl]but-3-en-2-one;N-[(3R,4S)-4-[[8-(cyclopentylmethylamino)-6-(2,6-dichloro-3,5-dimethoxyphenyl)pyrido[3,4-d]pyrimidin-2-yl]amino]oxolan-3-yl]prop-2-enamide;N-[(3R,4S)-4-[[6-(2,6-dichloro-3,5-dimethoxyphenyl)-8-[(3,3-difluorocyclopentyl)amino]pyrido[3,4-d]pyrimidin-2-yl]amino]oxolan-3-yl]prop-2-enamide;N-[(3R,4S)-4-[[6-(2,6-dichloro-3,5-dimethoxyphenyl)-8-[[1-(2-hydroxyethyl)pyrazol-4-yl]methylamino]pyrido[3,4-d]pyrimidin-2-yl]amino]oxolan-3-yl]prop-2-enamide;N-[(3R,4S)-4-[[6-(2,6-dichloro-3,5-dimethoxyphenyl)-8-[(1-methylpyrazol-4-yl)methylamino]pyrido[3,4-d]pyrimidin-2-yl]amino]oxolan-3-yl]prop-2-enamide;N-[(3R,4S)-4-[[6-(2,6-dichloro-3,5-dimethoxyphenyl)-8-(2-phenylethylamino)pyrido[3,4-d]pyrimidin-2-yl]amino]oxolan-3-yl]prop-2-enamide

N-[(3R,4S)-4-[[8-[(3-aminophenyl)methylamino]-6-(2,6-dichloro-3,5-dimethoxyphenyl)pyrido[3,4-d]pyrimidin-2-yl]amino]oxolan-3-yl]prop-2-enamide;1-[(3R,4S)-4-[[8-anilino-6-(2,6-dichloro-3,5-dimethoxyphenyl)pyrido[3,4-d]pyrimidin-2-yl]amino]oxolan-3-yl]but-3-en-2-one;1-[(3R,4S)-4-[[8-(benzylamino)-6-(2,6-dichloro-3,5-dimethoxyphenyl)pyrido[3,4-d]pyrimidin-2-yl]amino]oxolan-3-yl]but-3-en-2-one;N-[(3R,4S)-4-[[8-(cyclopentylmethylamino)-6-(2,6-dichloro-3,5-dimethoxyphenyl)pyrido[3,4-d]pyrimidin-2-yl]amino]oxolan-3-yl]prop-2-enamide;N-[(3R,4S)-4-[[6-(2,6-dichloro-3,5-dimethoxyphenyl)-8-[(3,3-difluorocyclopentyl)amino]pyrido[3,4-d]pyrimidin-2-yl]amino]oxolan-3-yl]prop-2-enamide;N-[(3R,4S)-4-[[6-(2,6-dichloro-3,5-dimethoxyphenyl)-8-[[1-(2-hydroxyethyl)pyrazol-4-yl]methylamino]pyrido[3,4-d]pyrimidin-2-yl]amino]oxolan-3-yl]prop-2-enamide;N-[(3R,4S)-4-[[6-(2,6-dichloro-3,5-dimethoxyphenyl)-8-[(1-methylpyrazol-4-yl)methylamino]pyrido[3,4-d]pyrimidin-2-yl]amino]oxolan-3-yl]prop-2-enamide;N-[(3R,4S)-4-[[6-(2,6-dichloro-3,5-dimethoxyphenyl)-8-(2-phenylethylamino)pyrido[3,4-d]pyrimidin-2-yl]amino]oxolan-3-yl]prop-2-enamide (PubChem CID 167696715) has the molecular formula C228H233Cl16F2N51O33 and a molecular weight of 4820.94 g/mol. Its IUPAC name is N-[(3R,4S)-4-[[8-[(3-aminophenyl)methylamino]-6-(2,6-dichloro-3,5-dimethoxyphenyl)pyrido[3,4-d]pyrimidin-2-yl]amino]oxolan-3-yl]prop-2-enamide;1-[(3R,4S)-4-[[8-anilino-6-(2,6-dichloro-3,5-dimethoxyphenyl)pyrido[3,4-d]pyrimidin-2-yl]amino]oxolan-3-yl]but-3-en-2-one;1-[(3R,4S)-4-[[8-(benzylamino)-6-(2,6-dichloro-3,5-dimethoxyphenyl)pyrido[3,4-d]pyrimidin-2-yl]amino]oxolan-3-yl]but-3-en-2-one;N-[(3R,4S)-4-[[8-(cyclopentylmethylamino)-6-(2,6-dichloro-3,5-dimethoxyphenyl)pyrido[3,4-d]pyrimidin-2-yl]amino]oxolan-3-yl]prop-2-enamide;N-[(3R,4S)-4-[[6-(2,6-dichloro-3,5-dimethoxyphenyl)-8-[(3,3-difluorocyclopentyl)amino]pyrido[3,4-d]pyrimidin-2-yl]amino]oxolan-3-yl]prop-2-enamide;N-[(3R,4S)-4-[[6-(2,6-dichloro-3,5-dimethoxyphenyl)-8-[[1-(2-hydroxyethyl)pyrazol-4-yl]methylamino]pyrido[3,4-d]pyrimidin-2-yl]amino]oxolan-3-yl]prop-2-enamide;N-[(3R,4S)-4-[[6-(2,6-dichloro-3,5-dimethoxyphenyl)-8-[(1-methylpyrazol-4-yl)methylamino]pyrido[3,4-d]pyrimidin-2-yl]amino]oxolan-3-yl]prop-2-enamide;N-[(3R,4S)-4-[[6-(2,6-dichloro-3,5-dimethoxyphenyl)-8-(2-phenylethylamino)pyrido[3,4-d]pyrimidin-2-yl]amino]oxolan-3-yl]prop-2-enamide.

Molecular Properties

Compound NameN-[(3R,4S)-4-[[8-[(3-aminophenyl)methylamino]-6-(2,6-dichloro-3,5-dimethoxyphenyl)pyrido[3,4-d]pyrimidin-2-yl]amino]oxolan-3-yl]prop-2-enamide;1-[(3R,4S)-4-[[8-anilino-6-(2,6-dichloro-3,5-dimethoxyphenyl)pyrido[3,4-d]pyrimidin-2-yl]amino]oxolan-3-yl]but-3-en-2-one;1-[(3R,4S)-4-[[8-(benzylamino)-6-(2,6-dichloro-3,5-dimethoxyphenyl)pyrido[3,4-d]pyrimidin-2-yl]amino]oxolan-3-yl]but-3-en-2-one;N-[(3R,4S)-4-[[8-(cyclopentylmethylamino)-6-(2,6-dichloro-3,5-dimethoxyphenyl)pyrido[3,4-d]pyrimidin-2-yl]amino]oxolan-3-yl]prop-2-enamide;N-[(3R,4S)-4-[[6-(2,6-dichloro-3,5-dimethoxyphenyl)-8-[(3,3-difluorocyclopentyl)amino]pyrido[3,4-d]pyrimidin-2-yl]amino]oxolan-3-yl]prop-2-enamide;N-[(3R,4S)-4-[[6-(2,6-dichloro-3,5-dimethoxyphenyl)-8-[[1-(2-hydroxyethyl)pyrazol-4-yl]methylamino]pyrido[3,4-d]pyrimidin-2-yl]amino]oxolan-3-yl]prop-2-enamide;N-[(3R,4S)-4-[[6-(2,6-dichloro-3,5-dimethoxyphenyl)-8-[(1-methylpyrazol-4-yl)methylamino]pyrido[3,4-d]pyrimidin-2-yl]amino]oxolan-3-yl]prop-2-enamide;N-[(3R,4S)-4-[[6-(2,6-dichloro-3,5-dimethoxyphenyl)-8-(2-phenylethylamino)pyrido[3,4-d]pyrimidin-2-yl]amino]oxolan-3-yl]prop-2-enamide
PubChem CID167696715
Molecular FormulaC228H233Cl16F2N51O33
Molecular Weight4820.94 g/mol
Exact Mass4810.31
IUPAC NameN-[(3R,4S)-4-[[8-[(3-aminophenyl)methylamino]-6-(2,6-dichloro-3,5-dimethoxyphenyl)pyrido[3,4-d]pyrimidin-2-yl]amino]oxolan-3-yl]prop-2-enamide;1-[(3R,4S)-4-[[8-anilino-6-(2,6-dichloro-3,5-dimethoxyphenyl)pyrido[3,4-d]pyrimidin-2-yl]amino]oxolan-3-yl]but-3-en-2-one;1-[(3R,4S)-4-[[8-(benzylamino)-6-(2,6-dichloro-3,5-dimethoxyphenyl)pyrido[3,4-d]pyrimidin-2-yl]amino]oxolan-3-yl]but-3-en-2-one;N-[(3R,4S)-4-[[8-(cyclopentylmethylamino)-6-(2,6-dichloro-3,5-dimethoxyphenyl)pyrido[3,4-d]pyrimidin-2-yl]amino]oxolan-3-yl]prop-2-enamide;N-[(3R,4S)-4-[[6-(2,6-dichloro-3,5-dimethoxyphenyl)-8-[(3,3-difluorocyclopentyl)amino]pyrido[3,4-d]pyrimidin-2-yl]amino]oxolan-3-yl]prop-2-enamide;N-[(3R,4S)-4-[[6-(2,6-dichloro-3,5-dimethoxyphenyl)-8-[[1-(2-hydroxyethyl)pyrazol-4-yl]methylamino]pyrido[3,4-d]pyrimidin-2-yl]amino]oxolan-3-yl]prop-2-enamide;N-[(3R,4S)-4-[[6-(2,6-dichloro-3,5-dimethoxyphenyl)-8-[(1-methylpyrazol-4-yl)methylamino]pyrido[3,4-d]pyrimidin-2-yl]amino]oxolan-3-yl]prop-2-enamide;N-[(3R,4S)-4-[[6-(2,6-dichloro-3,5-dimethoxyphenyl)-8-(2-phenylethylamino)pyrido[3,4-d]pyrimidin-2-yl]amino]oxolan-3-yl]prop-2-enamide
SMILESC=CC(=O)C[C@H]1COC[C@H]1Nc1ncc2cc(-c3c(Cl)c(OC)cc(OC)c3Cl)nc(NCc3ccccc3)c2n1.C=CC(=O)C[C@H]1COC[C@H]1Nc1ncc2cc(-c3c(Cl)c(OC)cc(OC)c3Cl)nc(Nc3ccccc3)c2n1.C=CC(=O)N[C@H]1COC[C@H]1Nc1ncc2cc(-c3c(Cl)c(OC)cc(OC)c3Cl)nc(NC3CCC(F)(F)C3)c2n1.C=CC(=O)N[C@H]1COC[C@H]1Nc1ncc2cc(-c3c(Cl)c(OC)cc(OC)c3Cl)nc(NCC3CCCC3)c2n1.C=CC(=O)N[C@H]1COC[C@H]1Nc1ncc2cc(-c3c(Cl)c(OC)cc(OC)c3Cl)nc(NCCc3ccccc3)c2n1.C=CC(=O)N[C@H]1COC[C@H]1Nc1ncc2cc(-c3c(Cl)c(OC)cc(OC)c3Cl)nc(NCc3cccc(N)c3)c2n1.C=CC(=O)N[C@H]1COC[C@H]1Nc1ncc2cc(-c3c(Cl)c(OC)cc(OC)c3Cl)nc(NCc3cnn(C)c3)c2n1.C=CC(=O)N[C@H]1COC[C@H]1Nc1ncc2cc(-c3c(Cl)c(OC)cc(OC)c3Cl)nc(NCc3cnn(CCO)c3)c2n1
InChIInChI=1S/C30H30Cl2N6O4.C30H29Cl2N5O4.C29H29Cl2N7O4.C29H27Cl2N5O4.C28H30Cl2N8O5.C28H32Cl2N6O4.C27H28Cl2F2N6O4.C27H28Cl2N8O4/c1-4-24(39)35-20-15-42-16-21(20)37-30-34-14-18-12-19(25-26(31)22(40-2)13-23(41-3)27(25)32)36-29(28(18)38-30)33-11-10-17-8-6-5-7-9-17;1-4-20(38)10-19-15-41-16-22(19)36-30-34-14-18-11-21(25-26(31)23(39-2)12-24(40-3)27(25)32)35-29(28(18)37-30)33-13-17-8-6-5-7-9-17;1-4-23(39)35-19-13-42-14-20(19)37-29-34-12-16-9-18(24-25(30)21(40-2)10-22(41-3)26(24)31)36-28(27(16)38-29)33-11-15-6-5-7-17(32)8-15;1-4-19(37)10-17-14-40-15-21(17)35-29-32-13-16-11-20(24-25(30)22(38-2)12-23(39-3)26(24)31)34-28(27(16)36-29)33-18-8-6-5-7-9-18;1-4-22(40)34-18-13-43-14-19(18)36-28-32-11-16-7-17(23-24(29)20(41-2)8-21(42-3)25(23)30)35-27(26(16)37-28)31-9-15-10-33-38(12-15)5-6-39;1-4-22(37)33-18-13-40-14-19(18)35-28-32-12-16-9-17(23-24(29)20(38-2)10-21(39-3)25(23)30)34-27(26(16)36-28)31-11-15-7-5-6-8-15;1-4-20(38)34-16-11-41-12-17(16)36-26-32-10-13-7-15(21-22(28)18(39-2)8-19(40-3)23(21)29)35-25(24(13)37-26)33-14-5-6-27(30,31)9-14;1-5-21(38)33-17-12-41-13-18(17)35-27-31-10-15-6-16(22-23(28)19(39-3)7-20(40-4)24(22)29)34-26(25(15)36-27)30-8-14-9-32-37(2)11-14/h4-9,12-14,20-21H,1,10-11,15-16H2,2-3H3,(H,33,36)(H,35,39)(H,34,37,38);4-9,11-12,14,19,22H,1,10,13,15-16H2,2-3H3,(H,33,35)(H,34,36,37);4-10,12,19-20H,1,11,13-14,32H2,2-3H3,(H,33,36)(H,35,39)(H,34,37,38);4-9,11-13,17,21H,1,10,14-15H2,2-3H3,(H,33,34)(H,32,35,36);4,7-8,10-12,18-19,39H,1,5-6,9,13-14H2,2-3H3,(H,31,35)(H,34,40)(H,32,36,37);4,9-10,12,15,18-19H,1,5-8,11,13-14H2,2-3H3,(H,31,34)(H,33,37)(H,32,35,36);4,7-8,10,14,16-17H,1,5-6,9,11-12H2,2-3H3,(H,33,35)(H,34,38)(H,32,36,37);5-7,9-11,17-18H,1,8,12-13H2,2-4H3,(H,30,34)(H,33,38)(H,31,35,36)/t20-,21+;19-,22+;19-,20+;17-,21+;2*18-,19+;14?,16-,17+;17-,18+/m00000000/s1
InChIKeyXTOFNSJXVVHNBJ-ZSSRQADQSA-N
XLogP39.71
TPSA1013.99 Ų
H-Bond Donors24
H-Bond Acceptors78
Rotatable Bonds83
Heavy Atoms330
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5004820.94
LogP ≤ 539.71
H-Bond Donors ≤ 524
H-Bond Acceptors ≤ 1078

Analyze N-[(3R,4S)-4-[[8-[(3-aminophenyl)methylamino]-6-(2,6-dichloro-3,5-dimethoxyphenyl)pyrido[3,4-d]pyrimidin-2-yl]amino]oxolan-3-yl]prop-2-enamide;1-[(3R,4S)-4-[[8-anilino-6-(2,6-dichloro-3,5-dimethoxyphenyl)pyrido[3,4-d]pyrimidin-2-yl]amino]oxolan-3-yl]but-3-en-2-one;1-[(3R,4S)-4-[[8-(benzylamino)-6-(2,6-dichloro-3,5-dimethoxyphenyl)pyrido[3,4-d]pyrimidin-2-yl]amino]oxolan-3-yl]but-3-en-2-one;N-[(3R,4S)-4-[[8-(cyclopentylmethylamino)-6-(2,6-dichloro-3,5-dimethoxyphenyl)pyrido[3,4-d]pyrimidin-2-yl]amino]oxolan-3-yl]prop-2-enamide;N-[(3R,4S)-4-[[6-(2,6-dichloro-3,5-dimethoxyphenyl)-8-[(3,3-difluorocyclopentyl)amino]pyrido[3,4-d]pyrimidin-2-yl]amino]oxolan-3-yl]prop-2-enamide;N-[(3R,4S)-4-[[6-(2,6-dichloro-3,5-dimethoxyphenyl)-8-[[1-(2-hydroxyethyl)pyrazol-4-yl]methylamino]pyrido[3,4-d]pyrimidin-2-yl]amino]oxolan-3-yl]prop-2-enamide;N-[(3R,4S)-4-[[6-(2,6-dichloro-3,5-dimethoxyphenyl)-8-[(1-methylpyrazol-4-yl)methylamino]pyrido[3,4-d]pyrimidin-2-yl]amino]oxolan-3-yl]prop-2-enamide;N-[(3R,4S)-4-[[6-(2,6-dichloro-3,5-dimethoxyphenyl)-8-(2-phenylethylamino)pyrido[3,4-d]pyrimidin-2-yl]amino]oxolan-3-yl]prop-2-enamide with MolForge

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Frequently Asked Questions

What is the IUPAC name of N-[(3R,4S)-4-[[8-[(3-aminophenyl)methylamino]-6-(2,6-dichloro-3,5-dimethoxyphenyl)pyrido[3,4-d]pyrimidin-2-yl]amino]oxolan-3-yl]prop-2-enamide;1-[(3R,4S)-4-[[8-anilino-6-(2,6-dichloro-3,5-dimethoxyphenyl)pyrido[3,4-d]pyrimidin-2-yl]amino]oxolan-3-yl]but-3-en-2-one;1-[(3R,4S)-4-[[8-(benzylamino)-6-(2,6-dichloro-3,5-dimethoxyphenyl)pyrido[3,4-d]pyrimidin-2-yl]amino]oxolan-3-yl]but-3-en-2-one;N-[(3R,4S)-4-[[8-(cyclopentylmethylamino)-6-(2,6-dichloro-3,5-dimethoxyphenyl)pyrido[3,4-d]pyrimidin-2-yl]amino]oxolan-3-yl]prop-2-enamide;N-[(3R,4S)-4-[[6-(2,6-dichloro-3,5-dimethoxyphenyl)-8-[(3,3-difluorocyclopentyl)amino]pyrido[3,4-d]pyrimidin-2-yl]amino]oxolan-3-yl]prop-2-enamide;N-[(3R,4S)-4-[[6-(2,6-dichloro-3,5-dimethoxyphenyl)-8-[[1-(2-hydroxyethyl)pyrazol-4-yl]methylamino]pyrido[3,4-d]pyrimidin-2-yl]amino]oxolan-3-yl]prop-2-enamide;N-[(3R,4S)-4-[[6-(2,6-dichloro-3,5-dimethoxyphenyl)-8-[(1-methylpyrazol-4-yl)methylamino]pyrido[3,4-d]pyrimidin-2-yl]amino]oxolan-3-yl]prop-2-enamide;N-[(3R,4S)-4-[[6-(2,6-dichloro-3,5-dimethoxyphenyl)-8-(2-phenylethylamino)pyrido[3,4-d]pyrimidin-2-yl]amino]oxolan-3-yl]prop-2-enamide?
The IUPAC name of N-[(3R,4S)-4-[[8-[(3-aminophenyl)methylamino]-6-(2,6-dichloro-3,5-dimethoxyphenyl)pyrido[3,4-d]pyrimidin-2-yl]amino]oxolan-3-yl]prop-2-enamide;1-[(3R,4S)-4-[[8-anilino-6-(2,6-dichloro-3,5-dimethoxyphenyl)pyrido[3,4-d]pyrimidin-2-yl]amino]oxolan-3-yl]but-3-en-2-one;1-[(3R,4S)-4-[[8-(benzylamino)-6-(2,6-dichloro-3,5-dimethoxyphenyl)pyrido[3,4-d]pyrimidin-2-yl]amino]oxolan-3-yl]but-3-en-2-one;N-[(3R,4S)-4-[[8-(cyclopentylmethylamino)-6-(2,6-dichloro-3,5-dimethoxyphenyl)pyrido[3,4-d]pyrimidin-2-yl]amino]oxolan-3-yl]prop-2-enamide;N-[(3R,4S)-4-[[6-(2,6-dichloro-3,5-dimethoxyphenyl)-8-[(3,3-difluorocyclopentyl)amino]pyrido[3,4-d]pyrimidin-2-yl]amino]oxolan-3-yl]prop-2-enamide;N-[(3R,4S)-4-[[6-(2,6-dichloro-3,5-dimethoxyphenyl)-8-[[1-(2-hydroxyethyl)pyrazol-4-yl]methylamino]pyrido[3,4-d]pyrimidin-2-yl]amino]oxolan-3-yl]prop-2-enamide;N-[(3R,4S)-4-[[6-(2,6-dichloro-3,5-dimethoxyphenyl)-8-[(1-methylpyrazol-4-yl)methylamino]pyrido[3,4-d]pyrimidin-2-yl]amino]oxolan-3-yl]prop-2-enamide;N-[(3R,4S)-4-[[6-(2,6-dichloro-3,5-dimethoxyphenyl)-8-(2-phenylethylamino)pyrido[3,4-d]pyrimidin-2-yl]amino]oxolan-3-yl]prop-2-enamide (CID 167696715) is N-[(3R,4S)-4-[[8-[(3-aminophenyl)methylamino]-6-(2,6-dichloro-3,5-dimethoxyphenyl)pyrido[3,4-d]pyrimidin-2-yl]amino]oxolan-3-yl]prop-2-enamide;1-[(3R,4S)-4-[[8-anilino-6-(2,6-dichloro-3,5-dimethoxyphenyl)pyrido[3,4-d]pyrimidin-2-yl]amino]oxolan-3-yl]but-3-en-2-one;1-[(3R,4S)-4-[[8-(benzylamino)-6-(2,6-dichloro-3,5-dimethoxyphenyl)pyrido[3,4-d]pyrimidin-2-yl]amino]oxolan-3-yl]but-3-en-2-one;N-[(3R,4S)-4-[[8-(cyclopentylmethylamino)-6-(2,6-dichloro-3,5-dimethoxyphenyl)pyrido[3,4-d]pyrimidin-2-yl]amino]oxolan-3-yl]prop-2-enamide;N-[(3R,4S)-4-[[6-(2,6-dichloro-3,5-dimethoxyphenyl)-8-[(3,3-difluorocyclopentyl)amino]pyrido[3,4-d]pyrimidin-2-yl]amino]oxolan-3-yl]prop-2-enamide;N-[(3R,4S)-4-[[6-(2,6-dichloro-3,5-dimethoxyphenyl)-8-[[1-(2-hydroxyethyl)pyrazol-4-yl]methylamino]pyrido[3,4-d]pyrimidin-2-yl]amino]oxolan-3-yl]prop-2-enamide;N-[(3R,4S)-4-[[6-(2,6-dichloro-3,5-dimethoxyphenyl)-8-[(1-methylpyrazol-4-yl)methylamino]pyrido[3,4-d]pyrimidin-2-yl]amino]oxolan-3-yl]prop-2-enamide;N-[(3R,4S)-4-[[6-(2,6-dichloro-3,5-dimethoxyphenyl)-8-(2-phenylethylamino)pyrido[3,4-d]pyrimidin-2-yl]amino]oxolan-3-yl]prop-2-enamide.
What is the SMILES notation for N-[(3R,4S)-4-[[8-[(3-aminophenyl)methylamino]-6-(2,6-dichloro-3,5-dimethoxyphenyl)pyrido[3,4-d]pyrimidin-2-yl]amino]oxolan-3-yl]prop-2-enamide;1-[(3R,4S)-4-[[8-anilino-6-(2,6-dichloro-3,5-dimethoxyphenyl)pyrido[3,4-d]pyrimidin-2-yl]amino]oxolan-3-yl]but-3-en-2-one;1-[(3R,4S)-4-[[8-(benzylamino)-6-(2,6-dichloro-3,5-dimethoxyphenyl)pyrido[3,4-d]pyrimidin-2-yl]amino]oxolan-3-yl]but-3-en-2-one;N-[(3R,4S)-4-[[8-(cyclopentylmethylamino)-6-(2,6-dichloro-3,5-dimethoxyphenyl)pyrido[3,4-d]pyrimidin-2-yl]amino]oxolan-3-yl]prop-2-enamide;N-[(3R,4S)-4-[[6-(2,6-dichloro-3,5-dimethoxyphenyl)-8-[(3,3-difluorocyclopentyl)amino]pyrido[3,4-d]pyrimidin-2-yl]amino]oxolan-3-yl]prop-2-enamide;N-[(3R,4S)-4-[[6-(2,6-dichloro-3,5-dimethoxyphenyl)-8-[[1-(2-hydroxyethyl)pyrazol-4-yl]methylamino]pyrido[3,4-d]pyrimidin-2-yl]amino]oxolan-3-yl]prop-2-enamide;N-[(3R,4S)-4-[[6-(2,6-dichloro-3,5-dimethoxyphenyl)-8-[(1-methylpyrazol-4-yl)methylamino]pyrido[3,4-d]pyrimidin-2-yl]amino]oxolan-3-yl]prop-2-enamide;N-[(3R,4S)-4-[[6-(2,6-dichloro-3,5-dimethoxyphenyl)-8-(2-phenylethylamino)pyrido[3,4-d]pyrimidin-2-yl]amino]oxolan-3-yl]prop-2-enamide?
The canonical SMILES for N-[(3R,4S)-4-[[8-[(3-aminophenyl)methylamino]-6-(2,6-dichloro-3,5-dimethoxyphenyl)pyrido[3,4-d]pyrimidin-2-yl]amino]oxolan-3-yl]prop-2-enamide;1-[(3R,4S)-4-[[8-anilino-6-(2,6-dichloro-3,5-dimethoxyphenyl)pyrido[3,4-d]pyrimidin-2-yl]amino]oxolan-3-yl]but-3-en-2-one;1-[(3R,4S)-4-[[8-(benzylamino)-6-(2,6-dichloro-3,5-dimethoxyphenyl)pyrido[3,4-d]pyrimidin-2-yl]amino]oxolan-3-yl]but-3-en-2-one;N-[(3R,4S)-4-[[8-(cyclopentylmethylamino)-6-(2,6-dichloro-3,5-dimethoxyphenyl)pyrido[3,4-d]pyrimidin-2-yl]amino]oxolan-3-yl]prop-2-enamide;N-[(3R,4S)-4-[[6-(2,6-dichloro-3,5-dimethoxyphenyl)-8-[(3,3-difluorocyclopentyl)amino]pyrido[3,4-d]pyrimidin-2-yl]amino]oxolan-3-yl]prop-2-enamide;N-[(3R,4S)-4-[[6-(2,6-dichloro-3,5-dimethoxyphenyl)-8-[[1-(2-hydroxyethyl)pyrazol-4-yl]methylamino]pyrido[3,4-d]pyrimidin-2-yl]amino]oxolan-3-yl]prop-2-enamide;N-[(3R,4S)-4-[[6-(2,6-dichloro-3,5-dimethoxyphenyl)-8-[(1-methylpyrazol-4-yl)methylamino]pyrido[3,4-d]pyrimidin-2-yl]amino]oxolan-3-yl]prop-2-enamide;N-[(3R,4S)-4-[[6-(2,6-dichloro-3,5-dimethoxyphenyl)-8-(2-phenylethylamino)pyrido[3,4-d]pyrimidin-2-yl]amino]oxolan-3-yl]prop-2-enamide is C=CC(=O)C[C@H]1COC[C@H]1Nc1ncc2cc(-c3c(Cl)c(OC)cc(OC)c3Cl)nc(NCc3ccccc3)c2n1.C=CC(=O)C[C@H]1COC[C@H]1Nc1ncc2cc(-c3c(Cl)c(OC)cc(OC)c3Cl)nc(Nc3ccccc3)c2n1.C=CC(=O)N[C@H]1COC[C@H]1Nc1ncc2cc(-c3c(Cl)c(OC)cc(OC)c3Cl)nc(NC3CCC(F)(F)C3)c2n1.C=CC(=O)N[C@H]1COC[C@H]1Nc1ncc2cc(-c3c(Cl)c(OC)cc(OC)c3Cl)nc(NCC3CCCC3)c2n1.C=CC(=O)N[C@H]1COC[C@H]1Nc1ncc2cc(-c3c(Cl)c(OC)cc(OC)c3Cl)nc(NCCc3ccccc3)c2n1.C=CC(=O)N[C@H]1COC[C@H]1Nc1ncc2cc(-c3c(Cl)c(OC)cc(OC)c3Cl)nc(NCc3cccc(N)c3)c2n1.C=CC(=O)N[C@H]1COC[C@H]1Nc1ncc2cc(-c3c(Cl)c(OC)cc(OC)c3Cl)nc(NCc3cnn(C)c3)c2n1.C=CC(=O)N[C@H]1COC[C@H]1Nc1ncc2cc(-c3c(Cl)c(OC)cc(OC)c3Cl)nc(NCc3cnn(CCO)c3)c2n1.
What is the InChIKey of N-[(3R,4S)-4-[[8-[(3-aminophenyl)methylamino]-6-(2,6-dichloro-3,5-dimethoxyphenyl)pyrido[3,4-d]pyrimidin-2-yl]amino]oxolan-3-yl]prop-2-enamide;1-[(3R,4S)-4-[[8-anilino-6-(2,6-dichloro-3,5-dimethoxyphenyl)pyrido[3,4-d]pyrimidin-2-yl]amino]oxolan-3-yl]but-3-en-2-one;1-[(3R,4S)-4-[[8-(benzylamino)-6-(2,6-dichloro-3,5-dimethoxyphenyl)pyrido[3,4-d]pyrimidin-2-yl]amino]oxolan-3-yl]but-3-en-2-one;N-[(3R,4S)-4-[[8-(cyclopentylmethylamino)-6-(2,6-dichloro-3,5-dimethoxyphenyl)pyrido[3,4-d]pyrimidin-2-yl]amino]oxolan-3-yl]prop-2-enamide;N-[(3R,4S)-4-[[6-(2,6-dichloro-3,5-dimethoxyphenyl)-8-[(3,3-difluorocyclopentyl)amino]pyrido[3,4-d]pyrimidin-2-yl]amino]oxolan-3-yl]prop-2-enamide;N-[(3R,4S)-4-[[6-(2,6-dichloro-3,5-dimethoxyphenyl)-8-[[1-(2-hydroxyethyl)pyrazol-4-yl]methylamino]pyrido[3,4-d]pyrimidin-2-yl]amino]oxolan-3-yl]prop-2-enamide;N-[(3R,4S)-4-[[6-(2,6-dichloro-3,5-dimethoxyphenyl)-8-[(1-methylpyrazol-4-yl)methylamino]pyrido[3,4-d]pyrimidin-2-yl]amino]oxolan-3-yl]prop-2-enamide;N-[(3R,4S)-4-[[6-(2,6-dichloro-3,5-dimethoxyphenyl)-8-(2-phenylethylamino)pyrido[3,4-d]pyrimidin-2-yl]amino]oxolan-3-yl]prop-2-enamide?
The InChIKey is XTOFNSJXVVHNBJ-ZSSRQADQSA-N. The full InChI is InChI=1S/C30H30Cl2N6O4.C30H29Cl2N5O4.C29H29Cl2N7O4.C29H27Cl2N5O4.C28H30Cl2N8O5.C28H32Cl2N6O4.C27H28Cl2F2N6O4.C27H28Cl2N8O4/c1-4-24(39)35-20-15-42-16-21(20)37-30-34-14-18-12-19(25-26(31)22(40-2)13-23(41-3)27(25)32)36-29(28(18)38-30)33-11-10-17-8-6-5-7-9-17;1-4-20(38)10-19-15-41-16-22(19)36-30-34-14-18-11-21(25-26(31)23(39-2)12-24(40-3)27(25)32)35-29(28(18)37-30)33-13-17-8-6-5-7-9-17;1-4-23(39)35-19-13-42-14-20(19)37-29-34-12-16-9-18(24-25(30)21(40-2)10-22(41-3)26(24)31)36-28(27(16)38-29)33-11-15-6-5-7-17(32)8-15;1-4-19(37)10-17-14-40-15-21(17)35-29-32-13-16-11-20(24-25(30)22(38-2)12-23(39-3)26(24)31)34-28(27(16)36-29)33-18-8-6-5-7-9-18;1-4-22(40)34-18-13-43-14-19(18)36-28-32-11-16-7-17(23-24(29)20(41-2)8-21(42-3)25(23)30)35-27(26(16)37-28)31-9-15-10-33-38(12-15)5-6-39;1-4-22(37)33-18-13-40-14-19(18)35-28-32-12-16-9-17(23-24(29)20(38-2)10-21(39-3)25(23)30)34-27(26(16)36-28)31-11-15-7-5-6-8-15;1-4-20(38)34-16-11-41-12-17(16)36-26-32-10-13-7-15(21-22(28)18(39-2)8-19(40-3)23(21)29)35-25(24(13)37-26)33-14-5-6-27(30,31)9-14;1-5-21(38)33-17-12-41-13-18(17)35-27-31-10-15-6-16(22-23(28)19(39-3)7-20(40-4)24(22)29)34-26(25(15)36-27)30-8-14-9-32-37(2)11-14/h4-9,12-14,20-21H,1,10-11,15-16H2,2-3H3,(H,33,36)(H,35,39)(H,34,37,38);4-9,11-12,14,19,22H,1,10,13,15-16H2,2-3H3,(H,33,35)(H,34,36,37);4-10,12,19-20H,1,11,13-14,32H2,2-3H3,(H,33,36)(H,35,39)(H,34,37,38);4-9,11-13,17,21H,1,10,14-15H2,2-3H3,(H,33,34)(H,32,35,36);4,7-8,10-12,18-19,39H,1,5-6,9,13-14H2,2-3H3,(H,31,35)(H,34,40)(H,32,36,37);4,9-10,12,15,18-19H,1,5-8,11,13-14H2,2-3H3,(H,31,34)(H,33,37)(H,32,35,36);4,7-8,10,14,16-17H,1,5-6,9,11-12H2,2-3H3,(H,33,35)(H,34,38)(H,32,36,37);5-7,9-11,17-18H,1,8,12-13H2,2-4H3,(H,30,34)(H,33,38)(H,31,35,36)/t20-,21+;19-,22+;19-,20+;17-,21+;2*18-,19+;14?,16-,17+;17-,18+/m00000000/s1.
What are the key properties of N-[(3R,4S)-4-[[8-[(3-aminophenyl)methylamino]-6-(2,6-dichloro-3,5-dimethoxyphenyl)pyrido[3,4-d]pyrimidin-2-yl]amino]oxolan-3-yl]prop-2-enamide;1-[(3R,4S)-4-[[8-anilino-6-(2,6-dichloro-3,5-dimethoxyphenyl)pyrido[3,4-d]pyrimidin-2-yl]amino]oxolan-3-yl]but-3-en-2-one;1-[(3R,4S)-4-[[8-(benzylamino)-6-(2,6-dichloro-3,5-dimethoxyphenyl)pyrido[3,4-d]pyrimidin-2-yl]amino]oxolan-3-yl]but-3-en-2-one;N-[(3R,4S)-4-[[8-(cyclopentylmethylamino)-6-(2,6-dichloro-3,5-dimethoxyphenyl)pyrido[3,4-d]pyrimidin-2-yl]amino]oxolan-3-yl]prop-2-enamide;N-[(3R,4S)-4-[[6-(2,6-dichloro-3,5-dimethoxyphenyl)-8-[(3,3-difluorocyclopentyl)amino]pyrido[3,4-d]pyrimidin-2-yl]amino]oxolan-3-yl]prop-2-enamide;N-[(3R,4S)-4-[[6-(2,6-dichloro-3,5-dimethoxyphenyl)-8-[[1-(2-hydroxyethyl)pyrazol-4-yl]methylamino]pyrido[3,4-d]pyrimidin-2-yl]amino]oxolan-3-yl]prop-2-enamide;N-[(3R,4S)-4-[[6-(2,6-dichloro-3,5-dimethoxyphenyl)-8-[(1-methylpyrazol-4-yl)methylamino]pyrido[3,4-d]pyrimidin-2-yl]amino]oxolan-3-yl]prop-2-enamide;N-[(3R,4S)-4-[[6-(2,6-dichloro-3,5-dimethoxyphenyl)-8-(2-phenylethylamino)pyrido[3,4-d]pyrimidin-2-yl]amino]oxolan-3-yl]prop-2-enamide?
N-[(3R,4S)-4-[[8-[(3-aminophenyl)methylamino]-6-(2,6-dichloro-3,5-dimethoxyphenyl)pyrido[3,4-d]pyrimidin-2-yl]amino]oxolan-3-yl]prop-2-enamide;1-[(3R,4S)-4-[[8-anilino-6-(2,6-dichloro-3,5-dimethoxyphenyl)pyrido[3,4-d]pyrimidin-2-yl]amino]oxolan-3-yl]but-3-en-2-one;1-[(3R,4S)-4-[[8-(benzylamino)-6-(2,6-dichloro-3,5-dimethoxyphenyl)pyrido[3,4-d]pyrimidin-2-yl]amino]oxolan-3-yl]but-3-en-2-one;N-[(3R,4S)-4-[[8-(cyclopentylmethylamino)-6-(2,6-dichloro-3,5-dimethoxyphenyl)pyrido[3,4-d]pyrimidin-2-yl]amino]oxolan-3-yl]prop-2-enamide;N-[(3R,4S)-4-[[6-(2,6-dichloro-3,5-dimethoxyphenyl)-8-[(3,3-difluorocyclopentyl)amino]pyrido[3,4-d]pyrimidin-2-yl]amino]oxolan-3-yl]prop-2-enamide;N-[(3R,4S)-4-[[6-(2,6-dichloro-3,5-dimethoxyphenyl)-8-[[1-(2-hydroxyethyl)pyrazol-4-yl]methylamino]pyrido[3,4-d]pyrimidin-2-yl]amino]oxolan-3-yl]prop-2-enamide;N-[(3R,4S)-4-[[6-(2,6-dichloro-3,5-dimethoxyphenyl)-8-[(1-methylpyrazol-4-yl)methylamino]pyrido[3,4-d]pyrimidin-2-yl]amino]oxolan-3-yl]prop-2-enamide;N-[(3R,4S)-4-[[6-(2,6-dichloro-3,5-dimethoxyphenyl)-8-(2-phenylethylamino)pyrido[3,4-d]pyrimidin-2-yl]amino]oxolan-3-yl]prop-2-enamide has a molecular weight of 4820.94 g/mol, XLogP of 39.71, 83 rotatable bonds, 24 hydrogen bond donors, and 78 hydrogen bond acceptors.
Where does this data come from?
All data for N-[(3R,4S)-4-[[8-[(3-aminophenyl)methylamino]-6-(2,6-dichloro-3,5-dimethoxyphenyl)pyrido[3,4-d]pyrimidin-2-yl]amino]oxolan-3-yl]prop-2-enamide;1-[(3R,4S)-4-[[8-anilino-6-(2,6-dichloro-3,5-dimethoxyphenyl)pyrido[3,4-d]pyrimidin-2-yl]amino]oxolan-3-yl]but-3-en-2-one;1-[(3R,4S)-4-[[8-(benzylamino)-6-(2,6-dichloro-3,5-dimethoxyphenyl)pyrido[3,4-d]pyrimidin-2-yl]amino]oxolan-3-yl]but-3-en-2-one;N-[(3R,4S)-4-[[8-(cyclopentylmethylamino)-6-(2,6-dichloro-3,5-dimethoxyphenyl)pyrido[3,4-d]pyrimidin-2-yl]amino]oxolan-3-yl]prop-2-enamide;N-[(3R,4S)-4-[[6-(2,6-dichloro-3,5-dimethoxyphenyl)-8-[(3,3-difluorocyclopentyl)amino]pyrido[3,4-d]pyrimidin-2-yl]amino]oxolan-3-yl]prop-2-enamide;N-[(3R,4S)-4-[[6-(2,6-dichloro-3,5-dimethoxyphenyl)-8-[[1-(2-hydroxyethyl)pyrazol-4-yl]methylamino]pyrido[3,4-d]pyrimidin-2-yl]amino]oxolan-3-yl]prop-2-enamide;N-[(3R,4S)-4-[[6-(2,6-dichloro-3,5-dimethoxyphenyl)-8-[(1-methylpyrazol-4-yl)methylamino]pyrido[3,4-d]pyrimidin-2-yl]amino]oxolan-3-yl]prop-2-enamide;N-[(3R,4S)-4-[[6-(2,6-dichloro-3,5-dimethoxyphenyl)-8-(2-phenylethylamino)pyrido[3,4-d]pyrimidin-2-yl]amino]oxolan-3-yl]prop-2-enamide is sourced from PubChem (CID 167696715), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).